LOCUS       c00023_gnlPro..        15579 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBLICJCB_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 13:03:08
            Original ID  :: gnl|Prokka|DBLICJCB_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15579
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15579
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2462:5579]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2463..5579
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15579
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15579
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             373..888
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1056..2045)
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MRMLEQIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARSLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2463..4721
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_3"
                     /sec_met_domain="Gly_radical (E-value: 4.2e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.9e-246, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             4758..5579
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_4"
                     /sec_met_domain="Radical_SAM (E-value: 6.8e-27, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             complement(5804..6115)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 67.1; E-value: 3.9e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg23_5"
                     /sec_met_domain="FeS_assembly_P (E-value: 1.1e-20,
                     bitscore: 67.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAEGTAEIT
                     MTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARMELGIHS"
     CDS             7176..8096
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAVDLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVILGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8266..8790
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTPNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(8885..9130)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_8"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00038, bitscore:
                     13.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSWSDK"
     CDS             9303..9731
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(9834..10475)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 2.5e-19, bitscore:
                     63.8, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAARYQAIPEDADFIAVFGGVNDYGRNQPLGQYGDCDMTTFYGA
                     LMVLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(11491..13158)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 410.4; E-value: 2.8e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_11"
                     /sec_met_domain="BCCT (E-value: 8e-125, bitscore: 410.4,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 ccctacacat ttgattcgtc gaaactttgt tcagttttca aagatctaat tccgtgtgtt
       61 aatcgcttaa cacaacttaa tcatcataac atcttaatca atatcttgtc aacaactttt
      121 ttaagaagta acttgattaa tttgtcgtgg ttgccattgc gacaacagaa actatcttac
      181 caattactga agaagttgtc aacaactaat ttcaataatt atttggtggt gagatgtatc
      241 tgccgtagca gcaacgttta ctaatatacc aattgaagta aaaagtgtca acactttttc
      301 tgaatttctt tttattaata gtcaaaccag ctttctttct ctatactatt taattaaagg
      361 agcgactaaa ttatgctagc ttggctacca ttctttttga tttcattaat gtttattgtt
      421 ctactatacg cttgtgcgcg atcagcgcgc acaaatatcc agcgttttaa gcaactcagt
      481 ttaattgcct ttctctgggt cttaactgct ttttgctaca cacctaccag ttacaatttt
      541 ggtacccaac tcgttattca atatattcaa tggggacccg ttaagctgaa cgtgattcct
      601 ttccaacaac ttgacattga attttggctc aacgttctcc tcactgttcc attgggcggt
      661 ttactggcat ggaattttcc cgacttgccc tggcgtcgtt ttatttggtt gggatttctt
      721 acggggctaa cactcgagct gggacaattc atccttgact ggttggttaa cctcaaacgt
      781 tgggttgata tcgatgatgt catcacaaat tgggctggtg tcattatcgg tgccgctggt
      841 tataaaattg cacgtcatgt tcccggactt cgctggttgc aaaaataacg tatatataga
      901 agcaaaaagc aaaatagcgt ttgcttagca cccacaagtg ccaaacactt cagcggtcta
      961 gctgtcatga aatcgtaatt aaataagcgt cgcagcctta agtggctgcg acgcttattt
     1021 aatttaacta ctaactatta atgaagctgc catcatcagg attcaaaaaa cagatcgaat
     1081 actcgcttac gatcttggtt ccagacctga ttgtcactag ttggataaac tcgatttgtt
     1141 aacacaacca gcccaatttg acgatccaaa tcaaaagcaa ctgccgggcc agtaaaacca
     1201 gtatggaaat attgatgtcg tcccgcacgt cgttcccaac ctaacgtccg gccattttcg
     1261 tcatactcgc ctaaccagtc aaagacattt tcatccagca cccgtttgcc ttgatattca
     1321 ccaaagttta acatcatttc aataaatacg gataaatccg tcagcgttga gaacaagcct
     1381 gcgtgaccac tctcaccatt caacaaaaag gctttataat catgcacctg tccttgaatc
     1441 tgaccccgcc gcggatcaaa ctccgtcggc acaaaccgaa tcttcggacg atttaagtta
     1501 taacccgtat tggtcatcgc tagtggatag caaacgtggt cttgaatact ccgagccaat
     1561 gagccgtcaa ccgcacgaat aatccatccc aataaaataa atcccaggtc tgaatagaca
     1621 tacgttgtcc ctggtgccgt gacgagtggc gcatcataaa ccgctttgat cagatcttca
     1681 cgttgcatct tatccaggtt atcaatatct gccggtagcc cactattatg aagtaacaag
     1741 tttttaatcg ttatttcagg atgagtgaac ccaggtaaag accgggcaac cgagtccgtt
     1801 aaatgaatcg tgtggtccga taacaactga aaaatcctcg tcgtggtccc tacaacctta
     1861 gttaccgatg ctaggtcata aatcatcgca ggatctaagc ccacggcaaa ctcatcgcgg
     1921 ccctgcttac catgatagta ttgattgata cctttagggg tgatcaagct aaacgacgcc
     1981 ccataaatgt cgccagcttc aatacaactg tcaatatatt gttcaatttg ttcgagcatc
     2041 cgcattacgc ccacctttca ctacattcac tagtttctgc ttatcttctt tatgataacg
     2101 aacttcctca taaaatcaac ggcaaacgct tttaacaccc tccacacctc gttgcacttt
     2161 ttattaatta actagttaaa cacttgttac attatggaca atattccact tatatatcaa
     2221 aacaagtctt gtttttagcc gttttctaaa tataattaag tgaattacca atgcctatct
     2281 agccatgtaa gtactgttat atcaacgtta atagtcaact tttcaataat agattgcaaa
     2341 aaaataaccc aaacgtgaaa taaatcacct gaaagcggtt acaaatccag caaaaaatgt
     2401 tatgattcaa atatagaatt ttatcaatca tttgattgga ttcaaattat ggaggcgaga
     2461 aaatgattac atcagaaaag acaacaaaac cagcagcttg gaaaggtttc aaaggcgggc
     2521 actggcagga agaaatcaac attcgtgatt ttattcaaaa taacttcaca cagtacaatg
     2581 gcgacgaaag cttcctggcc ggaccaacag ccgctactaa gaccttgaat gacaaagtct
     2641 tagaattaaa gaaacaagaa cgtgccgctg gtggtgtgtt ggatgctgat actaaagtcg
     2701 ttgcaacgat tacttcacac ggccctggtt atattcaaaa agatctcgaa aagattgttg
     2761 gtctccagac tgacaagcct ttgaagcggg ccttcatgcc atttggtggt attcgaatgg
     2821 ctgatgacgc tttgaaatca tacggttata cccctgatga agaaaacgac aagattttca
     2881 ctgaatatcg caagactcat aaccaaggcg tcttcgatgt ttatactcct gacatgcgga
     2941 aagcacgtca ctacaagatc atcaccggac taccagatgc atacgcacgt ggccgtctca
     3001 ttcctgatct tccacgggtc gctgtttatg ggatcgatcg tttaatggaa gacaaagcta
     3061 atgactttgc ccacattggt gatggtgaat tgactgatga tgttattcgc ctccgtgaag
     3121 aagttcaaga tcaataccgt gctttagcag atatgaagaa gatggctgcc agttatggct
     3181 acgacattag caagcctgca actaatgctc aagaagctat tcaatggatg tacttcgctt
     3241 acttagctgc tatcaagacc caaaacggcg ctgcaatgtc cgttggccgg attgatacaa
     3301 cgatggacat cttcatccaa cgtgacttgg acaatggtgt tctggacgaa agccaagctc
     3361 aagaattaat tgatcaattc gtcatgaaac tacggatggt tcggttcatc cgtactgaag
     3421 aatacaattc tctcttctct ggtgacccaa tctgggcaac cttatcaatg tgtggtttag
     3481 gcgtcgacgg tcaacaccat gtgactaaga ccgctttccg gattttaaag actttggaca
     3541 acatgggcgc cgcaccagaa ccaaacatca cgattttatg gtcagaccgc ttaccagaag
     3601 acttcaaacg ttacgcaact gaagtttcaa tcgacagttc aaccattcag tatgaaaatg
     3661 atgacttgat gcgggtacaa tggggtaccg attattatgg cattgcttgc tgtgtttccg
     3721 cacaaccaat tgctgatgga atccagtact tcggtgcccg ggcaaactta gccaaagcga
     3781 ttctttatgc catcaatggt ggccgcgacg aaattgctgg agatcaagtt ggccctgctt
     3841 acgaaccaat tacttcagaa tacatcgatt acgacgaatt catgaagaaa ttagacaagc
     3901 aaatggattg gttagctgac acttacgtta actcactgaa tgcaattcat tatatgcatg
     3961 ataagtacta ctatgaagct gcccaattag ctttgaagaa tactgatctt gatcggacct
     4021 ttgcaactgg gatttctggc ttatcacatg ccgcggattc aatctcagct atcaagtatg
     4081 gtcacgttaa agtaattcgt gacgaacgtg gtatcgccgt tgacttcaaa gccgacaatg
     4141 actacccacg ttatgggaac aatgacgatc gcgctgatga cattgctaaa tggttagtca
     4201 aagaattata cagcaagatg aacacgcatc acctctatcg gaatgccaaa ctttcaactt
     4261 ctgttttgac gattacctcc aacgttgttt atggtaagaa cactggtacc acaccaaatg
     4321 gccgtcaaaa aggcgaacca ttctcaccag gtgctaaccc tgcatacggt gctgaaaaga
     4381 gtggtgcatt agcttcactt ctttcaactg ccaaattacc ataccgttac gcaactgacg
     4441 ggatttccaa cacgttcggc gttactccta acacgttagg ccatgacctc gaatcacgga
     4501 aagacacgtt agtaaacatg ttagacggtt acatgaagaa cgatgggatg cacttgaaca
     4561 tcaacgtctt caataaagac actttgattg atgctcagaa acaccctgaa gaatacccaa
     4621 cattaacggt tcgggtttct ggctactgtg tctacttcgc agatttaacc aaggaacaac
     4681 aagatgacgt tatttcacgg acattcttcg aatcaatgta acatttaatc tttaatagtt
     4741 aagaaggcga aaggctcatg gaaaacaaac aagtttcaac aacgcaagcg gcggcaaagg
     4801 agcctttgat aggctacgtt cactccatcg aaacgtttgg ctccgttgac ggaccaggta
     4861 tccgttacgt ggcattcctt caaggatgcc acatgcgttg ccaatactgt cacaaccctg
     4921 atacttggaa actcaacgtt ggcgatcaaa tgacggccga cgagattctc gaagacgcgg
     4981 ctaaataccg ggctttctgg ggcaagacgg gtggcatcac agtcagtggt ggtgaatcac
     5041 tggtacaaat cgacttcatc ttagacttat tcgaaaaagc caaggcgatg aatatcagta
     5101 cttgtctgga tacctctgga cagcctttta cccgagaaca acctttcttt gacaagttcg
     5161 aacgtctaat gaaggtcacg gacatttcgt tggtcgacat taagcacatc gattctgcca
     5221 aacacaagca gttgacccag tatgggaacg aaaatatctt ggatatgatt cagtacatgg
     5281 cccaacacca cgatgatatg tggattcgtc acgtcctggt tccccaacgg actgattacg
     5341 atgaagactt gaagaaactc ggcgattaca ttgctaagat tccaaacgac gtcgttcaaa
     5401 aagtcgaagt attgccgtac catactttgg gcgttaaaaa atatcatgaa atgaagatca
     5461 agtaccggct tgaaggaatc gagtctccaa cccaagatcg ggtggcaaat gccgaaaaac
     5521 tactgcacac cgctgattac aacgggtaca agacatggat gccattgcca aaactttaaa
     5581 tcggcatttc tagcatgact aaaacaccag cgatacaatc gtctacggat ggttgtgtca
     5641 ctggtgtttt tttgctggct cgacgcatgc acgtattgct ggctggaatt agtacagtgg
     5701 cacgcaaaaa aggcgccgca agcctaaaac agcaacgtct ttccttaatc atgccctatc
     5761 caatgaccgt cagcccttga actagctgcg aacaggccgg ccactaacta tgaatgccta
     5821 gttccattcg agcttcgcgg gacatcatac tttcgttcca agcaggttcc cacacaatct
     5881 caatctcgat attgttaact tctggtaatt tgatcagttc atcgtgaatg tccttagcca
     5941 accattcggt caaaggacag cccgcaatgg tcaacgtcat ggtaatttca gcggtcccct
     6001 ccgccgtcaa ttgtgcatca tagatcaacc ccaagttaac tagatcaatt cctaattcag
     6061 ggtcaatgac atgtcctagc gcctcgaagg cccggtcttt aaacgttgtt gtcatcgtat
     6121 ctcgtccttc cataccagct tgaattcact gattaatcac gccaacgttt cgcggtataa
     6181 gtgccaccac acttgataca cgtcatcgtt atataaagcg ctttcttgtc tacttctatt
     6241 gtaccgtatg tcagcccata ttcaatcaat tattagcgct aattagccga cttttcaaac
     6301 gatcggtcaa tcagcaaatt atgcgactat ttctcgaaaa aatttactat aatccccgat
     6361 atagcagcgt tttgagtcac tattgatttt tattgcgaat tcgcggttgt ttttgttgta
     6421 agcgtttgcg gtttatgcta ttatactaag tgaggaaagg aattaatcct cgattagcaa
     6481 agcttctcaa aagagtttgg ctgtcgctgt aatgttagac agctagtatc acagtttggg
     6541 tcgttatcga aaccgtttta agcgccgtga agcgttatcg gtctagcgag tgtcgtgaga
     6601 tttacgttgg atgactgaac gttgaccctt agataaacga taaccgcaaa gaattaattg
     6661 gcattagaat gacgaacaga ttttaactaa gttttagttg gaaacaggtg tctctgatga
     6721 ccagttgtta gttccacatt accagttcca tttgtagact caggtattac aaagtttaaa
     6781 cggaggtgca tgtctgttac gaagacattc ccaagtttta aacgcgagtt tgactttcgt
     6841 taaaacccgt ctaacgagtc gcaatcaagt aacaacctta ctttagatcg actatagcag
     6901 atagttacaa taaatacggg ttagtccgtt agaagttgga cacgcgtaaa attgaatagc
     6961 atgaaggtgt atcatattaa cactgaacaa tttttcattg ctaatcagga ttattcctca
     7021 taagtagaac tcaagtagag aagccttggg ttctattttt tttgctctaa aatcagattt
     7081 accaacagtc ggcaccagtc gtaaccgttt acatcctctt acgaaaaccg tatactgaat
     7141 ttaaatcaag ttgcacattg aggaggactt tagttttgaa aacgattaat ttaggtcaca
     7201 gcaatattca agcttccagc gtggcgcttg gcatcatgcg catggacgcc ttggatgtcg
     7261 ctcaagccac caaggttatc gataccgctg ttgatttagg catcaattac gttgattcag
     7321 ctgatatcta cggtggtggt caatcatcga ccatcttcgg tcaagcactc aagcaggctc
     7381 acgtatcgcg tgatcagctc tatattcagt caaaaggcgg catcgttcct ggcaagcgtt
     7441 acgacttttc caaacagcac atactggcag ccgtggatgg cgaacttcaa cgcttaggtg
     7501 ttgattatct cgacaccttc ctcctccatc gaccggacgc cctgatggaa cccgaagaag
     7561 ttgctgccgc ttttgacaag ttgcaaacta gcggcaaggt gcgccacttt ggcgtctcta
     7621 acttcaatcc catgcaagtt gacatgcttc aagcggcact aaaccaacgg ctcatcatca
     7681 accaactcca atttggtatc atgcataccg gtgcgatcga ctttggcttg cacacgaaca
     7741 tgcaggacga acgtagtctt aaccacgacg gcgagatgat cgaatactca cggctccata
     7801 agatgacgat tcaagcttgg tcgccttatc aatacggtaa cttcgcgggt atcttcttag
     7861 acaatccgaa gtttccagaa cttaataatg ccatgcaagc actcgccgat gagaaacagg
     7921 tcactaaatc agctattgcg accgcatgga ttctccggca cccagcccac ttccaagtca
     7981 tccttggtac gatgaatccg gaacatctag ctcaaaatgc tgctggagca gacgttacgc
     8041 tttctcggca agaatggtac gacatttact ttgcagctgg caacgattta ccttaatcac
     8101 gatcgaccta acagaattga cgattagttt ttacaatcaa aacgacgacc ccaaatcagg
     8161 attgattttc aggtcgtcgt tttttagacg tttcactaac atttttgatg tactcaccac
     8221 atctacgcgt atacttaatc ttatcaagac tcaggaggcg agcgaatgac atccacttgc
     8281 acgatctgtg aacgaatcaa actaattcag gcacatcaga atccttattt cgtttacgaa
     8341 ctcacaacgg gctacgtggt ccttgctgat agccagtact ttgaaggcta cacgctcttt
     8401 ttagccaaac atcacgttac cgaattacat catttaccgg cacacgagaa gttacgatac
     8461 cttgaggaga tgagtatcgt ccaggaagct tgtgcgcagg cctttcatgc agacaaaatg
     8521 aacattgaac tactcgggaa tggtgacgcg catgttcatt ggcacttatt tcctcgccat
     8581 aacggtgata cgcccaaccc cggtcccgtc tggtggacac cgctggaaac aatttatggt
     8641 gatgatgtca gtctagacat tccccgttta agccggttaa agcgcacgct cagcgtagca
     8701 attgaggcca cgcttaatgc tcgggaagca gaattgcagg ctttagaggc actcacaagg
     8761 cctgctagcc acagaattga cagcaattag accaaatcag gacccagacc cgcttagatc
     8821 ttggtggcta caccccaatt cttaatcgca atccgtcacc gtatttcaaa ttgccaaaat
     8881 ccacctattt atccgaccaa ctatcatacg ctcgcttaga tttatagcca gctcgaaaaa
     8941 ccgtcttcat aacttcaatg tgccgttcct tagttgcttg tgccttagtt ccaaaaataa
     9001 agcgggccca ttcgcgctga taaccaggtg tcaaagccac aaagaacgtt tgcaattcag
     9061 catcaaccgc taacaattcg gttaccgccg gaatattttt ttcaaatgaa ctgaggggtg
     9121 ctgtactcat aatcaaacct ccgattagtt ttacttaaat ttactgtaag aaagggaaaa
     9181 tccctaattt tcaggttttt atatttcgaa ttttcataaa attgcgctat cattatagta
     9241 taagtattat tatttgacta ctataattaa ccatactgct attcaccaag gggagccctg
     9301 ctatgccaaa atttgatatc accctcatca gtcccgaacg cgctaaagcg atgttgactg
     9361 aatataaaga acaacgtaag aactctgtcc cacatctggc ccatcctggc cgctatatct
     9421 tgccggatta caaattaact cgtcgccggg ccgcattcaa aattgttaaa catacctttt
     9481 taacgcccca ctacaagtct tacgttgcca tggactctga caacggccac acactctggt
     9541 ttcataattt cggttcccta accgaagctt tattctggtt agaaaccggc cttaaaatca
     9601 gcgataccga ctcccattct aactacaagg aatggatggc taagcacact acggaaatcg
     9661 aaaccttcaa agacttgctg cgcgagcaga agcataaaca agggcccaag actaagaaaa
     9721 aagccaagta gcccgttttg acacctagat tcagataagc agcagtacgc ccattagcgt
     9781 gctgctgctt ttatttacga tcaactgtgc cattcattac tgactaggcc aacctaaaag
     9841 tggctatcca aaaacgactg cagcttgcgt gcaatcacgc gatgaccggc attgttcgga
     9901 tgcaaagtat ccaccgaata aatggccgct tgagcgggaa tcgcaaacgt cattcccgca
     9961 tcacggtaca agctcaaatg tgggacgcca tagtccgcag tcatctgggc aatcgctgct
    10021 tcataatctg actgacgata cccgagacca ttagtcaccg cactaaaact gccgccaaaa
    10081 tcagagccaa tatgaattgc tgaaataaat aacttcggca cggtcggcca attcgtctgt
    10141 aatcccgtca gtaacaccat taacgcgcca taaaatgtcg tcatatcgca atcaccgtat
    10201 tgccctaacg gctgattccg accatagtca ttgacgcccc caaagacagc aataaaatca
    10261 gcatcttcag gaatagcttg atagcgcgcc gccatcgcat cgtagcgact cccaatcgtt
    10321 gaaccagaga ttcccaaatt atcgctccgc tcgacatccc aatcagccgc caaaatatca
    10381 tgataatgca ccgtcgccaa cccattattc gccgtaatcg aatctcccaa ccacgccggc
    10441 cgcttaaaac taacatgccc attactaatc gccatagcca atcctccctt tactatcatc
    10501 gctatcattc taatccatcc cacctgaatt atggtagaaa gatgcctttt agggttggtt
    10561 ttctgttcgt cagccagtga gcgtcctatt ccgacctccg gggctgggtg acaattgctg
    10621 gaacgcagcc gacatcgatt tgagctaacg aataacccgc gtcatctcaa atacgagtct
    10681 tattctaagc cggaaggaaa tcacttccga ctaagaataa tttggctact gagcattgtc
    10741 acccagcccc tccagtctca agccacgggt tgaagccgag cattgtctag ccaacggatt
    10801 aatgcggttt gggcatttgt ccgttggcat agcaagcaca gactttagtg gcaccgaaca
    10861 cgtttcagga agccgctcga atggctgatg aacggccact taactcggca caattggtcg
    10921 ttggttattt tgatacagga actttaaacg agacgttagg gttaccctaa ccactttgtt
    10981 gaggtgttct attattacta tagtaattcc gaaatagcga gctatcccaa tatcttttcg
    11041 acctaacagt tgattaacaa aattactgtt tatggagaac aatgacaaat tcatcaaaag
    11101 ttgggtacat cttcgtccgc cattcgaata ctgtcccgac tggaaggcgt ttcggccaat
    11161 gctcagcggt gaaattccac ttagcaagcg tccttggctt ggttagtgga agaccagtat
    11221 ttaagacgtg gtcttcggct taaatctgtg tccaccgcgt tccagcaatt ggcagaaatg
    11281 cctggagggc ggcgtaggac gaacgaacta agcaggttta cgctaaccgg aactgtttcc
    11341 agcgggccta agctggtggc tgttgacttt aaataaaggc atctttatac cattatttca
    11401 aacaggtggg ccaagcttaa aaggctcgta ttatggaaat ccataatacg agcctagttt
    11461 aattgatata tttagttcaa ctgagtagcg ctaatcggct tccgtttcac gtttccgtgc
    11521 agtacgccgt tcgcgtgcgt agtcagtttt agttgtgatt tcaacgtcac gtgctagccg
    11581 tttccggcgt gctaattcag ctgctttggc attggctttc gcagcttcct tgactggatc
    11641 agtcgttaag tcgtgatgga tcgagtacag taagacgagc gcgacaatcg ttaatgggaa
    11701 gccagacatc gcacagatgg actgaatcga ttcaaagcca ccgaccgtga caagccccaa
    11761 tgagaagact aggaagataa cgacccagct catccgattg aaacgacttg gttgttcccc
    11821 cgcggccaac tttttactag taaatgacga ggtaatgaag gcaaatgaag ataccgtcgt
    11881 tgctaagaaa ataaagcaag ataggcagta caaagccagc ataatcatct tcaatggtaa
    11941 ggtcgacaat actgctgcaa tcacagcggc ttgtccttgc gtatttaaga tatgaactaa
    12001 gttaacgatg cccatccgtt gcaagtataa ggcataacca cccaagatgg cgtagaaact
    12061 gacacaacct aacgagcccc atagcaacat accaccgagt acctgacgaa tcgtccggcc
    12121 ccgagaaatc cgggcaatga ataagcccat gactggcata aaggataacc accagcccca
    12181 gtagaagatc gtctgccgtt gcatggccgt tgcgtgacca tttggtgcag tattcgtgct
    12241 caacgtaata aacttattga caaacaagcc aatactatta gtttccgagt ttaaaatata
    12301 caaagttggg ccaacaatta aaacaacgat taggaagcca atcgctaacc aaacatgggc
    12361 agcacttagc cgaccgattc ccttcttcaa gccattaaaa acagccatgg cgaaaattac
    12421 gaataataag gcaaataacc ctaactttaa agtcatcgta tcggcaatcc cggtaacggc
    12481 actcaaaact tttgaaatga cggggatttc catcccgact gaagtaccaa caccacccat
    12541 aatcccaata ataacgagaa aatcaatcgt gttccgggca atttgcttac ccttaccagg
    12601 accttgtagt actgaaattg cggcactgag ccgctgaacc ttgatgtgtt taacatacat
    12661 tgcataggca attgcaatcg tggctggcgc aaacatcatc cacgccattg gtccccaatt
    12721 aaattgtccc agcatgtgcg cataattata tgcagaagtt gaaaacggct tgacgccgaa
    12781 tgaagggctt tggaggtacc gtaacgggtc aaccatgctc aacattaaaa tgctggcatc
    12841 gatcccggtc gcgtaaacca tactgcccca gtgatacgtt gaaaattctg gtttgtcatc
    12901 aggatcacca agtttggttt tccctaactt actaaaccct aagtaaatga aaaagataaa
    12961 agtgatcaca tataccgaca tataaagcca gctcatgtta tttgtgagcc agttcaagat
    13021 gccacttaaa ctcgtctcca gcgaatggcc ccccattaat aaaacaacgg aagccgccgc
    13081 aaagagccca attgttggta aatagaccca ccaatcaata ttcttacttt ttaaaataat
    13141 aaacctgcta ctgagcatat actctctata tttagatcaa attcgtggtt cttcctacca
    13201 gcaatggtag tccccacgcg taaatttccg actagcaatc ggtacacccc tccgagttaa
    13261 tcctcggagc actcagcacc ctgactgtat caggtttgac cggcattgtc atccgcattc
    13321 tgtttgtgct aactcaaaat cagtagcaga atttccttct ttccgttggt tgaatccgga
    13381 caacgccata ctgacaaatg atttttaatt gcttaatcga cgttggtgtt catcttgttt
    13441 agctagtgtt tctattacca tcgtgccttt agcacacgac cgtcgtcaca ccacgtaacg
    13501 attaatggtt acactgctct tgctaataga taaccccctt gaatcaccag ataagcccac
    13561 cgcacaactg ttagattaat tgcttggtgc accaaaaaag cgcttagtac cgggtaacaa
    13621 gttaccacct gcacagcgca cgttggctta tacaaatgct gatttcagta ttttctgata
    13681 tctgatgttc gtttataagt atactagtat taaatcagaa gtaaaatcaa ccattttgag
    13741 ccgtcgaggc ctaacccgtc aaggattaga cgagttttac acccatattt tttctgaaac
    13801 tttttaaaag ttttcgtaat aattagtttt tagtttagaa tcattcttat ctgtttcaat
    13861 taaaccgatt tcatgttatt cttgtaacaa gtaaaaaaac gttatcatct aaaaggaggg
    13921 gaactgcatg cggcactact ataaattaat tttaacggtc agcgtcggta tcattgcggt
    13981 tattttacag tttggtttgc actaccaatt ggcagcacaa atcatcatta cattaatggg
    14041 gtcacttatg gccttatcaa tgttagttga gatgatcaaa accttacgtt caggtaagta
    14101 cggggttgat ttattagcaa ttacggcgat tgtggcaaca ctagctgtcg gcgaatattg
    14161 ggctagcctt gtcgttctaa ttatgctcac tgggggtgac tcgttagaag attatgcggc
    14221 caaacgagcg aataccgaat tgaaagcctt gctcgataat tcaccacgta ttgcccaccg
    14281 ctcagtcgcc ggccaattaa cagatattgc cgttgaagat gtccaaattg gtgatcagct
    14341 agtcgtcaaa cctggtgagc tagttccagt agacggtcac cttattcaag gaacggcact
    14401 ctttgatgaa tcttcattga cgggtgaatc taaaccagtc gacaagcacg ttggcgatga
    14461 cattatgtct ggtgcggtca acggcgatag tgccgttaca atggttgttg ataaattagc
    14521 cattgatagt caataccaac agttagtcaa attggttaaa gaatccgaat cacgaccagc
    14581 caaattcgta cggctggccg atcgctatgc agtcccattc accttggtag catacgtcat
    14641 tgccggagta gcttgggcat tcagcggtga tccccaccga tttgcagaag tcctcgtagt
    14701 ggcttcacct tgcccgctga ttctcgccgc acccgttgca ctcgtctcag ggatgagccg
    14761 aactagtcgg aacggaatcg tggtcaagac tggggacatg ttggagaagt tatctacggc
    14821 taagtccgcc gcgtttgata agacggggac cattaccagt ggtcaattaa cagtcaacca
    14881 aattgttcct cagcctggtt ttactgccga acaaatcttg cacctcgcag cgagcgctga
    14941 acaaaactca agtcatatcc tggcccgctc actcgtcaag tatgcgagtg ccactagcct
    15001 cagcccggca acacaattag cagaagtaac gggtaatggg gtcacggcaa cgattgagca
    15061 gcaacaggtc aaagtgggca aacttaaatt cgtcgcaccg actacgaccg ccgagccact
    15121 tgctactact gctatctacg tcggcatcga tgaccagtac gcgggttaca tcacgtttat
    15181 cgacaatgtc cgccccgaag cagccgccac gcttcaagca ctccacgctg agggcgttca
    15241 aaacgtcatg atgcttactg gtgaccaaca ggcaattgct gatcatattg ccgccgatgt
    15301 cggtatcgat accgttgctg ccgacctcct acccgcagat aagattgccc acttaaaggc
    15361 tgtaccagcg gccgaacgcc ccgttatcat ggttggtgat ggtgttaatg acgcgccttc
    15421 cttggctgtt gctgacgtcg gcattgccat gggcgcccat ggctcaactg ctgctagtga
    15481 atcggccgac gtcgtcatct taaaagacga tctcagtcgc gtggtcacgg cggtgcgcat
    15541 tgctaaagat accatgcaag tggctaaaca agccgtttg
//
