LOCUS       c00080_gnlPro..        16540 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CHPNEDDB_136.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 04:57:41
            Original ID  :: gnl|Prokka|CHPNEDDB_136
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16540
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16540
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3122:6680](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3123..6680
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16540
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16540
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(550..1704)
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1884..3089
                     /locus_tag="ctg80_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3123..6680
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6805..6993
                     /locus_tag="ctg80_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNVNAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7004..7864)
                     /locus_tag="ctg80_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7892..8722)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg80_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8719..9945)
                     /locus_tag="ctg80_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10418..11704
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11667..11999)
                     /locus_tag="ctg80_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12027..14780)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPHFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAIRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15113..16339)
                     /locus_tag="ctg80_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGLQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGRRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 cacatagcag ctattagaga taaacaagtc aaccattatt agggaagtac aatcttcaaa
       61 gagtttccat tgcttgaaac cagagtttca tcggtgtgaa actgtagttt catcggtgag
      121 aaactagagt ttcatacgct tgaaacttta gttccaaacg ctcgaaacta tctgaaacta
      181 ctgttgattt gattgactta accgcatgtt ccaatcacat tgaacgcatc agctacttca
      241 atagtactgc tctctctgaa aacattaaat catatatcag tcaataatac ataaattatc
      301 agtccttaat acttgatttc tcaattatta atatctgaga aatcaaacgt taacagttga
      361 gatatcagat attaacatcc tgtaaatcaa agaataacac agtaaaaacg gtatttatca
      421 ggacgatgca gagtgagagc aagtccttgc tctcactctg ctaccactgg atctctaaca
      481 gctaaaacat cgatgaataa agggatacag acgaactgtt agagcatgag agcaaaagca
      541 ctatcttttt cactggggga gagtaagcaa aagaaacgca cgataccggc tttgaggcgt
      601 caccggtact aacggcaaat atccggcaca cacccgatta ttctctacgg acaaagggaa
      661 cgaagccgac atctgccgat gttcctccaa agcctgaccg gctaaaggat aataatcaat
      721 ccgaaaaact ccttccgcat ccgcagccaa ataacgatcc gtcaagagcc atgccaccac
      781 ccccatattc attcgcagat taatttcgac acaaggatga atccggtaaa caggcgcttc
      841 atccggaaaa tgacaaatca tcatatccac tcccaagtat ccatgataaa agccaccgaa
      901 caaagctgac aattcttctt ccaaacgagt ccgcagcctg ataaattctt cttgtggcac
      961 ataagccgat agtttctgca gaatcttctc gtcagacagc aagtcattcc ctgcatacat
     1021 cccactccca cccgtgtgga agaccgaata tccggcaaaa acaacccttc ctctcccgtc
     1081 agcataaaac tccatagcga aatcttccac cttattatat ataggttcgc ctaccacccc
     1141 accctgagaa gcagcgacac gggcacacca accggaaata aaagtagtaa atatgccttt
     1201 acaccaattc aatcctttcc cgcttccgga aagcggagct tttaacaagc acgcttcccg
     1261 cccttcgacg aacgcactgc actccgccaa agtactcaaa taaaaagatt ctccacagaa
     1321 gtattcattc aaccgcaacc caggcaacaa ctttaccgcc tgcagacgat gcgaatgctc
     1381 tctcagaata ttcatataat ccgcagaagg cagctccgtc tgatctgccc ccaatgtcat
     1441 caaacgcttc cgcaaagcag ggtcccaccc ccacggagag aacttccggt ctttaccgtc
     1501 agccacttcc ggttccgtca acaaggccac atccatgccc aaaagttcac tctttgtttt
     1561 caggaagtcc gcattataag cagacggtgc aagcaccgca cttcccgctt cggcatacca
     1621 cataggaagc aacgccaggt cactcgccat ctgtcgggcg gaagccggcg ccatatagtt
     1681 cgtctcaccg cttgccaacg ccatatcatg ctccggattg aatatataaa caggtctttt
     1741 cgtcatgtca aagatggatt caacacatta ttctgcaaat atatacagga aataatcagg
     1801 aacttacaca ataaagagaa acttataaat taaagcacat ttttgctatc tctactttgc
     1861 aaatcctaaa aaaagcacta tatttgccag ccgaaaaaca aagaaacgaa atggaatcat
     1921 tctatcgcac acacgcctac ctcgttgagc acaccaatgc ccccgttcgc cgcgatctta
     1981 tggacgagat cgactggagt gaccgtctga ttggtatcaa agggacacgt ggcgtaggaa
     2041 aaaccacttt cctcctgcag tacgccaaag agaaattcgg caccgaccgt tcctgtctgt
     2101 tcatcaatat gaacaacttt tatttctccg gtcacagcct tgttgacttc gccaacgagt
     2161 ttcagaaacg tggcggaaaa gtactgctga tcgaccaggt gttcaaacat cccgaatgga
     2221 gcaaagagct acgaatgtgc tatgaccgtt tccccagcct gaagattgtc ttcaccggtt
     2281 cttccgtcat gcgactcaaa gaggaaaacc tcgaattgcg tgacattgcg aaaagttata
     2341 acctgcgcgg attctctttc cgtgaatttc tgaacctgca gacaggaatg aaattccggg
     2401 catacagcct cgaagaaatc ctcagtacac atgaacagat agccaaagga gtactttcca
     2461 aagtacgacc gctggattat tttcaggatt acctgcatca tggtttctac cctttcttcc
     2521 ttgaaaaacg taatttctcg gagaatctgc tgaaaacaat gaacatgatg gtagaagtgg
     2581 atatcttgct gatcaaacaa attgagctga aatatctttc aaagataaaa aaattactat
     2641 atttgttggc tgtggacgga ccgaaagctc cgaacgtgag ccaactggca agtgacgtac
     2701 agacatcccg cgctacggta atgaactata tcaagtatct ggcagacgcg cgtctgatta
     2761 atctggttta cccgaaagga gaagaattcc caaagaaacc gtcaaagatt atgatgcaca
     2821 actctaacct gatgtactcc atttatccgg tgaaagtgga agaacaggat gtactcgaca
     2881 cgttcttcgt taacacttta tggaaagacc ataaggtaca taaaggagat aaaaacgtct
     2941 ctttcatggt agacgaagtg atgccgttca aaatttgtgc ggaaggtaca aaaataaaga
     3001 ataacccgga cgtgacgtat gcgttgcaaa aggctgagat aggccgcggc aaccaaatac
     3061 ctctttggat gttcggattc ttatactaaa aagatttatt tacttaaata tttaatttag
     3121 ttatgactaa acagaagaaa ttcatcacat gtgatggtaa ccaagctgca gcacatatct
     3181 cgtatatgtt ctctgaagta gcagctatct accccatcac tccttcttcg actatggctg
     3241 agtacgtaga cgaatgggct gccgcaggac gtaagaacat cttcggcgaa acagtattgg
     3301 tacaggaaat gcaatctgaa ggtggtgctg ccggtgcagt tcacggttct cttcaggctg
     3361 gtgcattgac tactacttac actgcttctc agggtcttct tttgatgatc cctaacatgt
     3421 acaagattgc cggtgaattc ttgccttgtg tattccacgt ttctgctcgt acactggctt
     3481 ctcacgcatt gtgtatcttc ggtgaccatc aggacgtaat gtcagctcgt caaaccggct
     3541 tcgctatgtt ggcagaaggt tctgtacagg aagttatgga tttggcaggt gttgctcatc
     3601 tggctactat caaatcacgc gttccgttca tgaacttctt cgatggtttc cgtacttctc
     3661 acgaaatcca gaagatcgaa atgttggaaa acgacgacct cgctccgctg atcgaccagg
     3721 aagctttggc tgaattccgt gcccgtgcac tgaatccgat gaagccggtt gcccgtggta
     3781 tggctgaaaa ccccgaccac ttcttccaac atcgtgaatc atgcaataac tactatgaag
     3841 cagttcctgc tatcgtagaa gaatacatga acgaaatttc caagatcaca ggccgcaaat
     3901 acggtttgtt cgattactac ggtgcagaag atgcagaacg cgtaattatc gcaatgggtt
     3961 ctgtaactga agctgcccgc gaagctatcg accacttggt agcaaacggc gaaaaagtag
     4021 gtatggttgc cgtacacttg tatcgtccgt tctctgctaa acacttcctg gctgctgtac
     4081 ccaagactgc aaagagcatc gcagtgcttg accgtacaaa agaaccgggt gctaacggcg
     4141 aacctcttta ccttgacgtt aaagactgct tctatggcgc agaaaatgct cctgttatcg
     4201 ttggcggtcg ctacggtctg ggttcaaaag atacaactcc ggcacagatc atctctgtat
     4261 tcgaaaactt ggctatgcca atgccgaaga accacttcac tatcggtatc gtagacgacg
     4321 ttacgttcac ttctcttcct cagaaagaag aaatcgctct gggcggtgaa ggtatgttcg
     4381 aagctaaatt ctacggtctg ggtgctgacg gtactgtagg tgccaacaag aactctgtta
     4441 agattatcgg tgacaacacc gacaaacact gtcaggctta cttctcttac gactccaaga
     4501 agtcgggtgg tttcacttgt tctcacttgc gtttcggtga tactccgatc cgttctactt
     4561 acttggtaaa tactccgaac ttcgttgctt gtcacgttca ggcttacctg cacatgtacg
     4621 acgtaacacg tggtttgcgt aagaacggtt ctttcttgct gaataccatc tgggaaggcg
     4681 aagaactggc taagaacctg cctaacaagg tgaagaaata ctttgcacag aacaacatct
     4741 ctgtatacta tatcaacgca actcagattg caatggaaat tggtttgggc aaccgtacca
     4801 atacaatcct tcagtctgca ttcttccgta tcacaggcgt aatccctgta gatcaagctg
     4861 ttgaacagat gaagaaattc atcgttaagt cttacggcaa gaagggtgaa gacgttgtta
     4921 acaagaacta cgctgctgta gaccgcggtg gtgaatacaa gactctgact gtcgatcctg
     4981 cttgggctaa cctgccggat gatgcaaaag cagaaaacaa tgatcctgct ttcatcaacg
     5041 aagtagttcg tccgatcaat gcacaggacg gtgacttgct gccggtatct gcattcaagg
     5101 gtatcgaaga cggtacttgg tatcaaggta cttccaaata cgaaaaacgt ggtgtagctg
     5161 cattcgttcc cgaatggaat gctgaaaact gtattcagtg taacaagtgt gcttacgttt
     5221 gtcctcacgc ttctatccgt ccgttcgtac tcgatgctga agagcagaag ggtgctaagt
     5281 tcgagcaact gaaagctgta ggtaaagcat tcgatggtat gacattccgt attcaggtag
     5341 acgttctcga ttgtctgggt tgcggtaact gtgccgacat ctgtccgggt aatccgaaga
     5401 agggtggcaa ggcattgacc atgaaacacc ttgaaagcca gttggccgaa gctgataact
     5461 ggacttactg cgctgaaaac gtgaagagca aacaacacct ggtagacatc aaggctaacg
     5521 tgaagaactc tcagttcgca actccgttgt ttgagttctc aggcgcttgc tccggttgtg
     5581 gtgaaactcc gtacgtgaaa ctgatttctc agttgttcgg tgaccgtgaa atggttgcta
     5641 acgctacagg atgttcttct atctactccg gttcagttcc ttctactccg tacactatga
     5701 acgaaaaggg tcacggtcct gcatgggcta actccttgtt cgaagacttc tgtgaatttg
     5761 gtctgggtat ggaactggct aacgaaaaga tgcgtgcccg tctggtgaaa gtaatgaacg
     5821 aagctatcgc ttctgattgc tgcccggctg aatacaaaga agtatttgct gaatggatca
     5881 acaatatgct ggatgcagaa aagactaagg aactggccga aaagatcatt ccgatggtag
     5941 aagctgctaa agataaatgc aaccactgca agcaaatcgc tgatctgcaa caatatcttg
     6001 ttaaacgcag ccaatggatc atcggtggtg acggtgcttc ttatgatatc ggttacggtg
     6061 gtcttgacca tgtaatcgct tccggtaagg acgttaacat ccttgtattg gatactgagg
     6121 tttactctaa cacaggtggt cagtcttcta aagctactcc ggtaggcgct atcgctaagt
     6181 ttgctgctgc aggtaagcgt gtacgtaaga aagacctcgg tctgatggct actacttacg
     6241 gttatgtata tgttgctcag attgctatgg gtgctgacca ggctcagact ctgaaagcta
     6301 tccgtgaagc tgaagcatat ccgggaccat cactgatcat cgcttacgct ccatgtatca
     6361 accacggtct gaaagccggt atgggtaaga gccaggaaga agaagaaaag gctgttaagt
     6421 gcggttactg gcacttgtgg cgttacaacc ctgctttgga agaagaaggc aagaatccgt
     6481 tccaactgga tagcaaagaa cctaactggg aagacttcca aggtttcttg aagggtgaag
     6541 ttcgttacgc ttctgtaatg aaacaatatc ctgctgaagc tgaagaactg tttaaagctg
     6601 ctgaagaaaa cgctaaatgg cgttacaaca gctacaaacg tcttgccaga gaaaactggg
     6661 gagctgatac agctgaataa taagtagaaa tactttgtac ataataaaag gcaggaatcc
     6721 tggaaacaga ttcctgcctt ttttgtttat atcttagaag taacgattac ttctcacgaa
     6781 gatattcatt aaaactctaa agatatgatc ggatttgtta tttggattat cggtttgata
     6841 ctgactttca gagctgccat agagatttgg aatgtaaatg cggctgtaga gaaaagactt
     6901 atagcgattg tattaatcgt tcttaccagc tggctgggac tacttttcta ctacttctat
     6961 ggtaaagaaa gaatggcggg atggttgaag tagtgtttgc atatcaatct ttctcaggaa
     7021 tccaactgtt caccagttcc tgatgttctt ccatccattg acgggcagcc tgtctttccg
     7081 ttgtctgcgc ctcttccaga gcagtcatta aggagctgat ttccgcatct gtcagacgaa
     7141 tgttgcccaa aagttcggca gcaaaagggt ctttctcgct aaaacctttc catgctatgg
     7201 tatgaatgga ttccgtattt ccatatatca gcttcgggtc ctgaagaact ttcagcttga
     7261 aacggtcgaa catccagtga ggcgtccatc ccgtcacgac aatccagtct ttcttatcaa
     7321 tcgctttctt tagggaagca gtcatggcag gtccgctcga agtcatcagt ttataatcca
     7381 atccatagtc tttgatggcc tgatcggtag ctttcataat accggctccg gcatcaatac
     7441 cgacaatctg accggagaaa cgttcctttt ccgcgttcag ttcttcgatt gagttgatcg
     7501 taacgtaatc cggaaccacc agcccgatac gggcaccatc ataaatatcc ccgataactt
     7561 cgagtttatc cccgtattgt ttcatataat cttccatagt gacaggcatc cagacatcca
     7621 taaatacgtc tgctttctta cgggagatag aggtaaatat aggtgcaagg tcggcattca
     7681 gcaactttac atcgtacccc tgatcttcaa aaatcgcttt ggcaaggttt gtcattgcaa
     7741 taccttccga ccagttggca taagcgatac ttatcttctt actctttccg ttgtctccgc
     7801 aggaaacgaa ggttaagagt atgccggcaa taaacattgc cgcaatcatt tttatcttat
     7861 tcattgatta ttcctttctt tggtgtgatt cttatttctt tttacttttt ctgttatctg
     7921 ccataccctg agtgatgcgg tccagcacga tcgccaatat cacgactgcg ataccgcctt
     7981 caaatccgag tccgattttc atttgggtga tacctttcag cacgatttct cccaatcctc
     8041 cggcagaaat catggcagca atcactacca tcgaaagtga catcatgatc gtctggttga
     8101 ttcccgtcag aatagtaggc aacgccaaag gcaattgcac cttataaaga agctgccagg
     8161 gagtagctcc aaaagagcgg gaggcttcta ctacgttttt aggaacctga cgaatgccca
     8221 gaccggtcag acgaaccaca ggaggcattg caaagatgat ggtggcaaaa gctcccggca
     8281 cagttcccaa tccgaagaat agaacggcag gaatcagata gacaaaggca ggcattgtct
     8341 gcataaagtc gaggacaggg cgcattatct tgttacaacg atcactgttg gcagtccaga
     8401 ttcccaacgg aacgcctaaa agcaatgcca gacaagtgga agaaagtacc aatgccaatg
     8461 tctgcatcgt ttcttcccaa aagcccatgc cgtaaataag caataaaccc aagagggtaa
     8521 atacggctgt ccccttaccc gacttaaacc aggcgagcgc agccagcact gcaattgtga
     8581 tataaaaagg tattccaaac agtacgtgct gaaaaccgtc tatgaatcct ccgatcccca
     8641 tgctgagagc atcaaaaaag gaagcaaaat gttctgtgag ccaattaatg gcagtctcta
     8701 tatattgtcc gatatttatc ataattctat tgcgttttga atgatttcat taatttcttc
     8761 tttatctttt cccgttactt cgatgatcaa tgaggaaagt ggcactacgc cttcaaactc
     8821 ccgattctca tttacgaccc agattggcga gttcgttttt gtcatcaacg gaagaatatc
     8881 ttccagcacc gtatcaccca gcactgaatg aacttcatgc cttactacgg actcgatgga
     8941 gcggatttgc tcttttcgta gtttcagcaa gtcattcaac cgcacctctc ctactaacag
     9001 attattggaa tcgactaccg gaagaacggt cagattccgt tcgcgcatct tacggatcag
     9061 cacctccggg ccttctttct tcaaacgtgc cactatgggt ttatctacca taacagagga
     9121 agctgttata atcttgcttc gatctacatt ctccacaaat cgttctacat aagcgttggc
     9181 aggttcggtc aggatttctt ccgatgtacc gatttgtaca atttctccat ccttcatgat
     9241 agcaatccgg tcacccaatt taatcgcttc actcaggtcg tgagtaataa agacaatcgt
     9301 ttttttcatc ttcgactgca aagtcagcag ttcatcctgc atctgcacac ggatcaaagg
     9361 atcgagtgcc gagaaggcct catccatcaa caggacttcg ggattattgg ccaaagcccg
     9421 cgccagcccg acacgctgct gcatcccacc cgacagttca cttaccatct gattctcgta
     9481 gcctttcagc cccaccagtt gcatactttc catcgctttc tgctcccgtt ctcccttttt
     9541 tactccctgt agttcgagcc cgaaagctat attatgcaag acagaacggt gaggaagcag
     9601 accgaagttc tgaaagacca tagccagttc tttccggcga atctgcaaca gttccttatc
     9661 cgacactttg gctatgtctg ttccattgat aatcacttct ccggaagtag ggcgtatcaa
     9721 acggttgatg cagcggagta aagtggactt tccactaccg gacagcccca taatgacgaa
     9781 tatttcgcct tcattaatgg aaagattcgc atctttcacc gcaactgtac atccggtcgc
     9841 tttcaatatt tcactttttg ttttaccttc tttcaacatc ttcaaagcct tctgcttctc
     9901 attgccaaaa accagataga gatctttaat ttctatttta ctcatacaat aaaatggttt
     9961 aggttattaa aataatatac acagcaagac aagaacaaac gataacagga atctttcttt
    10021 atatcgtata aagttctgat ttaaataagg gacaaataac aatgaatccc gaaataatta
    10081 ataaaatgat tattgacaga ctgagtaatt aaaaaaggaa tagaatttga taagataatc
    10141 ctttcaacga atagcaaaaa atagcatttt tatgtataaa aacagcctgt tccagtatct
    10201 tgctggcaca aagatacaaa aaacggatta aacatacaaa ttatattcaa aatccggggc
    10261 atacagaggg ctttatttgt aatgatatgg aaagtttccg ggtaatattc ccctatcact
    10321 cagcaaaata gaacaaaccg gcagataaat ataaaataag tttgaatatt tcacttaaac
    10381 accgtatatt tggcgtcaat aactaaacta gatttatatg ttcaacaggg ctattacaat
    10441 tttcctgggg aaggataatt gtcattacac aacaaaagaa aaacaaacag gtactgccac
    10501 actagacgac aaaagccaag tacagttcct tagtaaaaag aaccccaaaa tgccgttttt
    10561 ctatagccgg cggaatctct acatgatagg tttcctgctc gcttttatag tgactctgct
    10621 cgaatttata cgaggacggc atcaaaactt tatggtcttc tcggacgcta ctcaattctt
    10681 ctggcaaggc atcagcccat acacaactga atttgtagaa gctcacggac gctacttcct
    10741 ttattctcca gttttcacgg tattgttcgc tccgtttgcg tatctgcctg catggctggg
    10801 acctttcgcg tggaatctat tcaattattc gctgttcttt atggcgatct tcacgctgcc
    10861 ccaacaattc acccagcagc agaaatgccg tatgttcctt tttctgttac tgattttagg
    10921 acaaagttta ctttcatttc agtataacat aacggtagcc tatttattct tattcgccta
    10981 tacgttattg gaaaaagacc gtggatttct ggctgttctg ttaatcatga tttcgggatg
    11041 taccaaagta tatggaattt tcgaactggc attgttgctg tgctatcctc acgtatggcg
    11101 taactttggc tatgccgtta caatgggcat tgtattgctt gcattaccgt taataaaaat
    11161 agctcctgca gatttgctcc cctattatga agaatggtgc catagtcttg ctgttcatca
    11221 gtccgccgga gcttatgatt catttttcta tgcccgcccc attgcagcat ggacattgcc
    11281 acacttccgt gcacttcaga taggaatgct cggcttgctg actctgctct ttttggggaa
    11341 tttccgcaaa tggtcgtctt ttgccttccg tgcccaggct ttgggcattc tcatgggctg
    11401 ggtagtatta ctgagtgact ccgccgagaa gcatacctat attatcgcat tggcaggttt
    11461 catgctctgg tattggagca gaccaacacg taccgcaaca gacaagattc tattttggtg
    11521 ctgttttgtg ctgttatgta tcgttcctat cgacatattc gtccctgtac ccatcagaga
    11581 tttcattacc aggaccttat ggcttcatgt atgggttttc tttattgtat ggatacggat
    11641 gatatggctt accttccttg catccttcat tcatccacgt gccacaaatg ttctttcaga
    11701 ttaacgcatc cgttagcttt gaaagaaact tcttctgcca gcaagagttg tttttgttcc
    11761 acccaaccgg gcaccagcct tccggtggaa tttacaactc tatggcaggg aatggataat
    11821 tcatccggca cttctttcaa tgcacgtccc accatccgcg agcattgggg tgcccccaac
    11881 agcaaagcaa tacctccata agtagatact tttcccacag gtatctggga tacgacttcg
    11941 tacacttcct tccgaaagga ttcggaaaag ctctctttat ctactttata atctttcata
    12001 tatccctctt tacgatatca atgaaatcat cctttccttt tcaggaaatc tgtcgggctc
    12061 tctccaaact gctctttata gcacttggcg aaataagaag gtgaactgaa accgacttca
    12121 taaccaatct ccgctacggt catgtccgaa gaagcaagca aagaagctgc cttcttcaaa
    12181 cgggcgatac ggagcaattc attcggagag tagttagtca atgatttaat cttgcgataa
    12241 agctgcacac ggcttagtcc catgtctttg cccaagtcct ccacattcaa accggagtct
    12301 cccattttct cttcaatcaa tgacttgaat ctttctacaa aatccttgtc catatcgcag
    12361 acatcttctt ttgccaatgt ctgcccgtca ccaaagaact gtttcagacg acggtgagaa
    12421 tcgatcagat tgcggacacg tgccagcaac agctgtgaac tgaacggctt tgaaatataa
    12481 gaatccgcac caccgtcata tccctgaata cgctgttcgt ccagtgaaca cgctgtcagc
    12541 agaataaccg gaatatgaca ggtctgtaac tcacttttca gccggcggca acattcaatg
    12601 ccatcaatgc ccggcatcat cacatcagaa atgatcaggt ccggaacata cttcatagcc
    12661 ttacggattc cttcggagcc gtctgccgct tcaatcaccg tatagtctgt atgcaacagc
    12721 gtatggacat acgaacggat atcctcatta tcatcaataa tcagtacgga cggtttggaa
    12781 gagtcatatc ctttttccag ttcttcctct tctgccaata gaacatctgt tgtacgggaa
    12841 tccgcagaaa caagggtggt atccggttcg gcagcaacag cctcacaaga ctgtacaggc
    12901 agttcaacgg taaagaccgt gccctgtttc tcatcgctct ctacggagat cataccaccg
    12961 tgcatttcta cgaaggcttt taccaatgcc agtccgattc ccgaaccggt atggtgcata
    13021 tcaatcttat agaaacggtc gaatacattg cggatatgtt cggcagaaat catggaaccg
    13081 gtatttgcca ccgtgaaacg tatccatcgc ttgtcctctt tactaaggga agacagacgg
    13141 atggctattt tcccgttttc cggtgtaaac ttaaaggcat tggacaggag attgaaataa
    13201 atacgttcca gcttctccat gtctgccagt gtatgataat ccgtatccgg catactatca
    13261 aaagaaaaat ggatatgctt cttacgggct gccgcctgaa aagactcatt ccatccttcg
    13321 aaagaagaaa ggacatccac cgtaaccgga gtatattcca tcttgccgtt ttcatattta
    13381 cggaaatcca aaatctgatt gaccaggcgc aaaaggatat tcacatttcg ctgaatcagc
    13441 atgagcatcc ggtgctgatc tccactcaat gtcttgtccg ccaataaatg ttctaccggg
    13501 tcggcaacca atgtcaacgg agtacggaag tcgtgagaaa tattggtgaa aaagaccagc
    13561 ttggcatggg tagcttcttc cagttgatga gagagctgta tcaattggtc acgctgttct
    13621 tccagtttgt cacgctgctc ttccaattgc tgcttctgct taaaaagctc tttattcaag
    13681 cgattcttag agcggagtga tttataaacg accaataata agccggctac caataaaagg
    13741 ataatcagac tgccgtataa aacgacctgt tgtgtagcta cctgagagag gtatccaccg
    13801 atacgtccgt tgagcgtttc aatcttttta tcgagttcgg agatgtgtgt agtctgcaac
    13861 tgcatgacgt gtgcgttggt acggtccaca acagcggtat tcatcaccgt ttctttggga
    13921 tagggtttct tctccagaat gtccatagcc agttgcagta ccttatcgcc attggtcgga
    13981 tagataaagg tggcatccag cacactgtcc aaaaccagtt ccagtccgtt tcccttaccc
    14041 ggcaaggcat ctatgccgac aaaaatcatt tccttctccc gccctgccat ctttgctgcc
    14101 tgataggcac ccggagcgat acggtcatta tgggcataca cagcatcaat cttaggatgc
    14161 ctccgaagca tactatccat ttctatctct gccggaccac gttcccacgc agcatccgct
    14221 ttatcaatca gctttatatc cgggaattta ctgatggcag ccataaatcc ctgatgccgt
    14281 tccattgcag gagtcgaacc gctcaatcct gtcagttcta ctatatttcc cttccctttc
    14341 agactggagg caatatagtt tcctaccgaa cgaccgattt cataattatc ggctccgata
    14401 taggcagtat atttatccga aagaatcttc cggtctacaa gaataacggg gatgcctttc
    14461 tgataagctt cttctacaat cggagtcata ggagcagctt cgttagcgga aataatcagc
    14521 agatcgactc cttcgtccat aaaataatgg acatcttccg cctgcttact gttatcatct
    14581 cctgccgaac ggatttccac cgaaacgcca ttataaaaca ttgcttcccg aagaatctca
    14641 tcattcatct tatgtcgcca tgaatcatcg ctgcattgag ccaccccaat acgaaaatgg
    14701 ggtgtatcct gccggcaagc cgtcatcccg attaaaccaa acagcaccag catccacttc
    14761 agatatctca tcgtcttcat ccatctcatc atttcatagt tctttctgta atccaattaa
    14821 gaacaaaaat aagaaataat actgtaaagt tctctaactt cagctattta ttattctaaa
    14881 aagaaggaaa gcagtcctct ttcagaccat cggaaagtat taacaaaagt ataaagcgta
    14941 aaacaaacac ttaatcaatg ttataaaaca tagcgtttta cttggataat ttgcagattt
    15001 cacagaagtc cgtatctttg cactgtgttt ttcatagtat tagatttaag gttaacaaag
    15061 gttggagcaa ggcgttgctc ctttttttat gccctgacct ttcatctacc ggttagtttt
    15121 catcccattc cttttccagt ttaccatcaa tagtgtagcg tttccatcgt cctacacggc
    15181 gaccattctt atattcccca cattcacgaa gctggtcatt ctttacataa cgagcttcga
    15241 acggtccgtt ctgccttccg ttcacatagg tagaagtttc ccaataatca aagcggttgc
    15301 tcactatcag ccgtcgttcc ttgccatgca atctgccggc ctgataggta gcttcatatc
    15361 tcaattcacc attttccaga ttatattcac ggtataaacc gtctttacga tcgttcttca
    15421 tataatattc tttctgcctt accccacttc cgttggcaaa tgagacatgg agtccatctt
    15481 cttttccatc cagataggtt tcaatcatca gcgtatctcc gctttcagca aaagtagtcc
    15541 accgaccatt cttctttcca ttcttataac tacccagtat acgtggcgag ccaaacgtaa
    15601 acacggacga atattcaccg tcctgcaaac cttcttcatt gaaataaacg gtctcataca
    15661 aatcatatgt acctttcaga aaagtatact gtttgcctac ctgcttcccg tccttgtaat
    15721 tatgctcttt ccgcaaagta ccgtcagatt cgtacgacag ttgcttcccg tgctctttcc
    15781 ccatccggaa gtttctttca ctttccactt ttccggtagt aaagtaactt ttgctcgtac
    15841 cgtccagctt accttcctta taggactttt cttctttcag cttaccgtca aacttggagt
    15901 taatcttgaa gaggccatcc ttccgccctt ctttataact tccttccgtt attaatatat
    15961 tgtccacata ttctttgtat ccgccatcat aaaaaccatc tttaaaagat gccagcacat
    16021 aggcggaatg ataaccatct atgatgcgat gttcgccatt caatgctttt tccgttttca
    16081 gttcctgaaa caacagtctg ccatcgccta cattaacaac agatacctga tcgatcttat
    16141 attccttttg cgcaaacaaa ggaagagcaa gatataaaaa caaaaatacg ttccagcttt
    16201 ttgatctgag gaagttcgaa atgtgtttca taaagtagtt ttctcttttt gatttattat
    16261 ttaaaaacct gccgcaaaga taggcaatcg gcttataaaa caaggcaaga aagaggggga
    16321 caattagaaa aaagaacatc tgttattatc attctaataa ttaacagatt aagtagtaaa
    16381 tcaaaacaca gggaaggggg acatttactg aaataagaaa cagaaaagaa gatgtgtcaa
    16441 aagcaactaa attcccctcc ttcaggaagg aggagagttt agttgctttt gacacattta
    16501 catttgcagt attaaatatc acaacaaaat ataagtgtat
//
