LOCUS       gnlProkkaAPIBCANP_86   19738 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|APIBCANP_86.
ACCESSION   gnlProkkaAPIBCANP_86
VERSION     gnlProkkaAPIBCANP_86
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:46:11
            Original ID  :: gnl|Prokka|APIBCANP_86
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19738
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..19738
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[6980:9738]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6981..9738
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..19738
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..19738
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             3..176
                     /locus_tag="ctg25_1"
                     /transl_table=11
                     /translation="MDVSIIGLTVKPFTNDRQHTAVFTTHIGKITDIIKMIQTGNTQHN
                     PSNFSTIRTKSW"
     CDS             complement(128..532)
                     /locus_tag="ctg25_2"
                     /transl_table=11
                     /translation="MQPLSSLRTKILEFMYSSEDLERFYFQYQTEALPHGESLQSFCVK
                     NKVPYNIFQKWYKDTRKKVVEVQVDGAPAIGHEEKSRASDQPQPVSPSRDDHPVRIWVG
                     IRISNGLHLSQKNLSYQDLVRMVEKLEGLC"
     CDS             complement(533..670)
                     /locus_tag="ctg25_3"
                     /transl_table=11
                     /translation="MNTDERSVEVVNLISELYWIESDCKIHFLSEDERRKERKQSKNGY
                     "
     CDS             complement(667..903)
                     /locus_tag="ctg25_4"
                     /transl_table=11
                     /translation="MEYKKQYIWGSKNPALKVAYYLYDWGSRSMAVAENHFKDFFGNIT
                     TDGYNVYKLFDRHRKGVTRYGCMAHVRRKFVDA"
     CDS             complement(855..1712)
                     /locus_tag="ctg25_5"
                     /transl_table=11
                     /translation="MANSEQEKSDLREALKALQQTRADDLFELERQKRQLYGRSSGKVK
                     SLKKLQERSVKEDKDDFDGFNPPGLPPHEGHALLDTMRSSDALVGQAAKSKPHRSDYGK
                     NATQIESTVMHYCNRDQVPADARPIDVRHWILYKMDWNVCKHVFEIPRLIDSEGAISNY
                     YASFEGDEALHPFENVLPGHHVGMDMIAQIMVDKYQYSLSSERGVARFSDAGAKFSSST
                     VLSWIQKHTDLLGKQETPLRNLLLSKDSFCSVMGLLNWSESKTRKRERWNTRSSISGAA
                     RIRP"
     CDS             complement(1705..1806)
                     /locus_tag="ctg25_6"
                     /transl_table=11
                     /translation="MQDKDIINILISQLLSKDDELRHQRSRLETPFG"
     CDS             complement(1915..2226)
                     /locus_tag="ctg25_7"
                     /transl_table=11
                     /translation="MNFYLCEGFVDMRKGIATLSELVRRKLHKDPESGDVFIFLGKDRR
                     NIKILRHEYNGYVLYWQKLNRERFLLPVFNSDLNQYEISWDKLVVLLQGTVRKGILVG"
     CDS             complement(2241..2663)
                     /locus_tag="ctg25_8"
                     /transl_table=11
                     /translation="MALDLYIFYFYFRDLNLKLFQVMNMSEFYSDFLYRYQTEAAPLNV
                     SIDSFCLREGVEYRNFIRWYRDNKKRLRESEMADIRISAIKVTGAPALTAPVNPPIAFC
                     TVSEFHLKLSNGIEIHKPDSHLEDITNLLSSLSRVC"
     CDS             complement(2786..3511)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     98.8; E-value: 5e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_9"
                     /transl_table=11
                     /translation="MGDDRGTLSMNSYKAFIEEREVSIYRFPYELVDSNMFFIPSGDTG
                     IVFDPNENEELLRVFQELGTRSVEIVLTHEHYDHTTGVKWLQSKIETRLFCHRACAEAI
                     ATEKGNDPKTLGYILTLRDAVDGGHRRENFLATAKRYMLRADEAFDGDCGLKVGELVLR
                     CHPAPGHSPGSALYFLGETAFFSGDSLIQHTPTIVHLPGSDRRAYKQETKPYLRSLDKD
                     MMVFPGHGEPFKLGEAEFL"
     CDS             complement(3487..3702)
                     /locus_tag="ctg25_10"
                     /transl_table=11
                     /translation="MSERPKKIFCFDNYPEAKMVLGKVTYPVIIKPYECEDKTFWFEAS
                     DYGKAGQVLYDAFEHTRNGWVMIEEH"
     CDS             complement(3699..4733)
                     /locus_tag="ctg25_11"
                     /transl_table=11
                     /translation="MDFLKKLPTPEELAKIYPLSKGMAKKKLEHDKEIKKIFSGESKRL
                     LLNIGPCSADRMDAVLEYAARLAEIQKEVVENILIVPRVYTSKPRTIGKGYMGMIHQPY
                     IGQGEDLSMGVAAVRNVHRQVVEETGLFPSDELLYPETIHYLADLLGYAVIGARSVENQ
                     QHRLVASGLNIPVGLKNPISGSINVMLNAIETAQHPHHFIFNGWEVMSKGNEYAHGVLR
                     GYLEEGGAATRNCDYEHLSEICDRFAVRNVENPAVVVDCNHSNSDKQYMRQIDNAMEVL
                     GLMKEYPKIKKLVKGLMIESYLEDGNQPIDGGVYGKSVTDPCLGWEKSKQLIYDINEKL
                     EGLK"
     CDS             complement(4736..5983)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 76.4; E-value: 4.3e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_12"
                     /transl_table=11
                     /translation="MGGKKTRTERVNEYYQNTKYLNMEQVTIGMAGAGRATELHIMALK
                     RFLGVPVRLKTIVARRKEQLEEAQRLYGFEQISYSFDDMINDPEIDVIDICTPPYAHEE
                     MIEKAMMAGKHVICEKPLTGYFGTPGDEEPIGDKVPKRVMYLKMLEQIRYLRTVIKKTG
                     KKFMYAENFVYAPAVRKTAEIIKAKKSRILFMKGEESLKGSSSPVAGEWSKTGGGTMIR
                     TGAHPLSAILWLKQQEAQARGVEIKVKSVLGVMDRITPQLNEYEHRHIAARPHDVEDFG
                     TIILDFTDGTKAVVIATDTLLGGSKNYVELYCNDAAINCNLTMSNLMSTYFLDEDNLDD
                     VYISEMLPSKTGWNNPFLEDEIIRGYTDEMRDFMECVYYDREPQSGFTLAYDTIKIIYA
                     AYMSAELGNKVELNAF"
     CDS             complement(6175..6600)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 118.9; E-value:
                     3.9e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_13"
                     /sec_met_domain="DHQ_synthase (E-value: 8.2e-52, bitscore:
                     167.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTLLFMVDASISGKTAVDLQAGKNLIGAFWQPSLVVADTQVVT
                     NLPADIFAEGMAEVIKSDLIANAGIVEMIRQNTIKERIDQMVASCIKMKRDVVEQDEYE
                     TKGLRKVLNMGHTVPHAIEKLSNYSISHGVAVATGLV"
     CDS             complement(6619..6933)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_14"
                     /sec_met_domain="DHQ_synthase (E-value: 3.8e-14, bitscore:
                     44.3, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGQGVIADLPRLVEPFCKGGKVGVITDDTVDALYAAKAVWAMEQY
                     GYDVCKYVIPYGESSKNINTLSGILEYFASCHFTRKDIFLSIGGGVIGDITGVPAALYM
                     "
     CDS             complement(6981..7931)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 93.1; E-value:
                     3.2e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_15"
                     /sec_met_domain="HMGL-like (E-value: 3.1e-24, bitscore:
                     77.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNIEGIKIVDATIRDGGLVNDFFFTDEFVKKVYETNVAAGVDYM
                     EFGYRADKKMFDPSKFGKWKFSSDEDIFSIVGDNPTGLKLCVMADVGRCDFKNDIHKKS
                     DSPLSLIRVATYIETFSEAIEMIEFAAKQGYEVTCNLMAISKCTMMQLSKALDALAQTP
                     VMGVYIVDSYGALYPKEVRKLTRHFQDHLSPYGKLTGIHAHNNQQCAFANTIEAHDLNA
                     KMLDATYYGMGRGAGNCHLEALLGYFNGKKYHVEPVLDLVGSDMLVMKDQEPTWGYNTS
                     YLIAGLANAHPRDAIAATKKKDTNFVEQYKFQIYK"
     CDS             complement(7939..8190)
                     /NRPS_PKS="Domain: PP-binding (29-72). E-value: 7.4e-07.
                     Score: 21.5. Matches aSDomain:
                     nrpspksdomains_ctg25_16_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_16"
                     /sec_met_domain="PP-binding (E-value: 7.5e-07, bitscore:
                     21.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDIKEFVTEYIQREYTVPEDVDIMTLNYIEAGYIDSMAFIQFIS
                     TIEDEYDIEFEVEDIENPKLRIVGKLIDFIQAKIDEQH"
     aSDomain        complement(7975..8103)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg25_16_PP-binding.1"
                     /evalue="7.40E-07"
                     /label="ctg25_16_PP-binding.1"
                     /locus_tag="ctg25_16"
                     /protein_end="72"
                     /protein_start="29"
                     /score="21.5"
                     /tool="antismash"
                     /translation="IEAGYIDSMAFIQFISTIEDEYDIEFEVEDIENPKLRIVGKLI"
     CDS             complement(8206..9738)
                     /NRPS_PKS="Domain: AMP-binding (9-409). E-value: 1.8e-80.
                     Score: 262.4. Matches aSDomain:
                     nrpspksdomains_ctg25_17_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     314.7; E-value: 1.5e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg25_17"
                     /sec_met_domain="AMP-binding (E-value: 8.5e-84, bitscore:
                     273.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSQLADLFYKNAAEMPDKQAIWCDGKTATYQEMANRVSRYSNYL
                     VAKGVQYGDHVAIPMNNSIESVALFFSAADLGVCLVPLNPTLPLESIKVAMKSGDMKHL
                     IARKSFLNECEKKGGVDVPGITVCLDGEFEGAFPFSEVATMPTTRPACENIKGDESLIL
                     TMTSGSTGTPKPIDISQQNKIDRSLAHIRVYGLVKEDRILAATPLYHSLAERLVIMPLL
                     LGATSILLPRFTPALWLKCAAEQKPTFTIAVSAQLAQILELLKQENTESIDSFHTIVSS
                     SALLEEKVKLELIDRLQCEFHEMYGTSETSTATDICFQKARNKQKSVGLPFDEAEVKIL
                     RDDEDTECAVGEVGEIAVKSKLTCKGYYKLKNMMDMATTEGFFRTGDLGYMDEDGYLYF
                     AGRKKELIITGAINVYPNDVDAVVNQLTAVEECAAFSYPDERLGEVVALAVVVKEDCEL
                     TERTIKTYCAKNLADFQQPHKIFFVDMLPKNTMGKLQRNRILDHIRNVGIDK"
     aSDomain        complement(8512..9711)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg25_17_AMP-binding.1"
                     /evalue="1.80E-80"
                     /label="ctg25_17_AMP-binding.1"
                     /locus_tag="ctg25_17"
                     /protein_end="409"
                     /protein_start="9"
                     /score="262.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="YKNAAEMPDKQAIWCDGKTATYQEMANRVSRYSNYLVAKGVQYGD
                     HVAIPMNNSIESVALFFSAADLGVCLVPLNPTLPLESIKVAMKSGDMKHLIARKSFLNE
                     CEKKGGVDVPGITVCLDGEFEGAFPFSEVATMPTTRPACENIKGDESLILTMTSGSTGT
                     PKPIDISQQNKIDRSLAHIRVYGLVKEDRILAATPLYHSLAERLVIMPLLLGATSILLP
                     RFTPALWLKCAAEQKPTFTIAVSAQLAQILELLKQENTESIDSFHTIVSSSALLEEKVK
                     LELIDRLQCEFHEMYGTSETSTATDICFQKARNKQKSVGLPFDEAEVKILRDDEDTECA
                     VGEVGEIAVKSKLTCKGYYKLKNMMDMATTEGFFRTGDLGYMDEDGYLYFAGRKKELII
                     T"
     CDS_motif       complement(9205..9249)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg25_17_0001"
                     /evalue="8.60E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg25_17"
                     /protein_end="178"
                     /protein_start="163"
                     /score="12.4"
                     /tool="antismash"
                     /translation="TMTSGSTGTPKPIDI"
     CDS             complement(9740..10843)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 204.5; E-value: 3.6e-62)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_18"
                     /sec_met_domain="fabH (E-value: 1.4e-50, bitscore: 164.1,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEGYPSVVETRITIMAKIKINNVRIKGIAACAPSKVEENSEYPY
                     FDENEFENIIPSIGVERRHVAKEGQTCADFAQRAAEKLMEELGWEKESIDLLIFGSPSK
                     DYIQPDTACVLQGKLDLPESCMAFDMTLGCTGWTYGMTNACSLMQTGCIKRVLLLNGIQ
                     GSAESCYYDKTGYPLFSDVATATALEYDPTAAPIYCELGTIGKQFDAILVPDGGRRNPV
                     TEGSLKLVEYEKNVKRNRLHTFMKGMDVFSFALKTAPKSTNAVLEFAGKEKDEIDYFFF
                     HQANFYMVKKIIKKLKIDPEKAPIVMKDFGNTGACSIPFTMVIGCAEKLRNGKHTNVGC
                     SFGVGLSWGSLCFETENLVIPELQIYD"
     CDS             complement(10815..11561)
                     /NRPS_PKS="Domain: PKS_KR (10-168). E-value: 1.3e-10.
                     Score: 33.3. Matches aSDomain:
                     nrpspksdomains_ctg25_19_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     177.9; E-value: 4.1e-54)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_19"
                     /transl_table=11
                     /translation="MYNPYSLTGKTILVTGASSGIGRATAIECAKLGAKVVITARNEDR
                     LKETLDTLEGEGHQMICFDLSETEKLNDFVASLPPVQGFVSNAGTTIIAPIKFIKEDSL
                     EGLLQVNTVSPILLLQRLLKKRILGKGSSVVFTSSMAALGKGTPGNTMYSASKGAISAF
                     IQNAALELSAQRIRVNAVCPGTVDTPLIHSGGITDEQLSEDAKKYPLGYGQPEDIALGI
                     AYLLSDAAKWVTGTNVIIDGGLSVSC"
     aSDomain        complement(11058..11531)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg25_19_PKS_KR.1"
                     /evalue="1.30E-10"
                     /label="ctg25_19_PKS_KR.1"
                     /locus_tag="ctg25_19"
                     /protein_end="168"
                     /protein_start="10"
                     /score="33.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TILVTGASSGIGRATAIECAKLGAKVVITARNEDRLKETLDTLEG
                     EGHQMICFDLSETEKLNDFVASLPPVQGFVSNAGTTIIAPIKFIKEDSLEGLLQVNTVS
                     PILLLQRLLKKRILGKGSSVVFTSSMAALGKGTPGNTMYSASKGAISAFIQNAA"
     CDS_motif       complement(11439..11531)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg25_19_0001"
                     /evalue="9.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg25_19"
                     /protein_end="41"
                     /protein_start="10"
                     /score="15.0"
                     /tool="antismash"
                     /translation="TILVTGASSGIGRATAIECAKLGAKVVITAR"
     CDS             complement(11567..11797)
                     /NRPS_PKS="Domain: PP-binding (6-70). E-value: 1.6e-08.
                     Score: 26.8. Matches aSDomain:
                     nrpspksdomains_ctg25_20_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_20"
                     /sec_met_domain="PP-binding (E-value: 1.7e-08, bitscore:
                     26.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNEFIENFAEQFDDTDASEIKADTVFKELDEWSSLVALSVIAM
                     VDEEYDITIKGDEIWNSNTVEDLFNAIKAKA"
     aSDomain        complement(11588..11779)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg25_20_PP-binding.1"
                     /evalue="1.60E-08"
                     /label="ctg25_20_PP-binding.1"
                     /locus_tag="ctg25_20"
                     /protein_end="70"
                     /protein_start="6"
                     /score="26.8"
                     /tool="antismash"
                     /translation="IENFAEQFDDTDASEIKADTVFKELDEWSSLVALSVIAMVDEEYD
                     ITIKGDEIWNSNTVEDLFN"
     CDS             complement(11834..12469)
                     /locus_tag="ctg25_21"
                     /transl_table=11
                     /translation="MKHLVIIGGGGMGKDIYHSAKHSIGYGTEYDIKGFIDDNLNSLDG
                     CEGYPPVLDTIKNYQPSEDDVFTCSIGNVKTKRTLCEMIKDRGGKFITLLHETAQLGEN
                     VKLGDGCIIDSHAHIGSDTIIGENCLVQTFAGIGHDCRVGDYCRIDVRAFLVGGVRIEE
                     NVTIHTNAILNHHVVVEKDAVVAALSFVVRKVKAGTTVFGNPAKLLKY"
     CDS             complement(12484..13092)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 240; E-value: 8.8e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_22"
                     /sec_met_domain="Bac_transf (E-value: 8.3e-64, bitscore:
                     206.2, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKHFFKRPFDFIISLVALICLSPILLAVTIWLHFANKGAGAFFI
                     QARPGKDAEIFKVIKFKTMKDEFDEKGEPLPDEVRLTKVGKIVRSTSLDELPQLLNVLK
                     GDMALIGPRPLMPEYLELYTPEQMRRHEVRPGITGWAQIHGRNELPFTERFEYDVYYVD
                     HLTFGLDLKIFFMTIVKIFKREGISQKGQATVETFDGTN"
     CDS             13122..13316
                     /locus_tag="ctg25_23"
                     /transl_table=11
                     /translation="MPSITYHNARLNNYRRIAGYYGVGGGIFGYNSTCGYNAMISNGYT
                     GQNDTANTNHTILSNPSVK"
     CDS             complement(13578..14747)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_24"
                     /sec_met_domain="Wzy_C (E-value: 6.1e-08, bitscore: 24.7,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIPVKTSKWFTYYLLFLPLVMMYSVPGTGIRIPTLLTAIAMLYS
                     LLQLANRHMRVPIYMLLPLFMYLTYVMFKSSLQLAFLCGSVIIIISAICTGIVNVFLLR
                     KVLEKVAIVAAFCVIFQQIVHILTGIHFHFYLLPFFANDLLEQYNNAITTGAVEGMYRP
                     CAFFLEPAQYSQYCTIGLGSCLFTHRPKTKNALFISLGIFASTSGMGFVSVFAIWGAWA
                     LSRQKTKKNFIRSLPVILIALFLVFFLLDNISFTHNIINRFTSTSGDDYNAINGRLFWW
                     DTYFGDFNISDFLTGFGLDNLPDGVYFTGFMKLLYCYGLIGTTLLLLFLGMLIIKADIF
                     VKVCTSLYTGLLFFADLTYYHNLIFYIGVYLALYIFNKERVNIAGTLKA"
     CDS             complement(14752..15576)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 96.4;
                     E-value: 3.4e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_25"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.4e-27,
                     bitscore: 85.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLIPDVIAKLRGYKVILHAHNNGLQKGGRMYLMAHNLGKILSR
                     FCGFVMFTNSQLSSDYMFGKGVNSKLIYNAIDVGKFAFKQEHRDCIRKELDCQSKTVIG
                     FVGRLVDQKNPLFMLKVFAEIHKLRPNSELWIIGEGILRGKMEVEINEQGICSSVKWLG
                     RREDVNRLMQGMDLLLQPSVFEGLGIVLVEAQATGLAVVSSEVVIPKEAVISDRIKLLP
                     LSEKPAYWAAESVNLLDSCCESYDRTNAIVPDCYNIQHEAKRLESMLKELIS"
     CDS             complement(15888..17621)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.5;
                     E-value: 8.5e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_26"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-23, bitscore:
                     75.4, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKIKQVQQIVSLLKQNNIRHFVLSPGTRHVAFVHIVEMDPFFR
                     CYSIVDERSAAFFALGLSEALDEPVGFACTSATASCNYMPAMKEAYERNIQLVALTSDK
                     QRYQRFHGVSQVINQVDMFAPYCRYAVDLPEVNDSMDEWFCNRCINEALLEMDHHGRGP
                     IQINFLEPSSIDELSIFYDGNMPVCRKINRIEDWSQINEWKNVLAAKKRILVVCGQYQE
                     FTGCLRSSIRKFYEKYNCAVSFDAFSNVADKDFIQTMLLSITLNQKELLSLKPDLIITF
                     GTKYFSDIVSRFAGMGIEHWEINFEGRIFDTSRSLTKIFEFTPEEFFDKVSYNITTNDK
                     QYDKLWRALNESRDNSIDEFTNYYVAKKVLESLPEGSNVHASVLNSMKFTNMSKLPQNT
                     IATGNNCADGIDGALSTFIGQAEVLDSLSLLVIGDLSYLYDLNAAIHDFKNNTRVLLIN
                     NFAGGEFHFNIGKKKISTLEQHIAAGHHTKIQDAISLSNFQYIAVHNKGELEEKLSLFL
                     RESENPILMEVFTNPELDGSSLKKLIRNNIKMTPERLIAGFVNKFLDCRTKYAIKKFLH
                     R"
     CDS             complement(17627..18457)
                     /locus_tag="ctg25_27"
                     /transl_table=11
                     /translation="MIDSIISCLNAKGVVRFVNTTTQIKEKISYPSNIEWYYIEDVRSA
                     VFNAYGMSKISHSPVAIIVEEAYLPNTYTALTEAWLQRVQVIVLALNSMNLDSSFYLNR
                     CVDASILIDNVETIEGVVCNAIQHHGPSLIKIKEEVNEEKKIDYTNLFSIIDLCAKDKK
                     VLCYNPQYGNKDYEFIPPEYKYGVISKYVGQLIGGKQSVLCIPEYLLALDTNIFNFRDF
                     PDGFKLIVKYSDGVCWGRLNTWMQRNNINTYVVDGRSFEYTTMNFKPNYAILVK"
     CDS             complement(18492..19139)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     94.4; E-value: 1.3e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg25_28"
                     /transl_table=11
                     /translation="MICGRQEETLRRACRELGESCQYIKFDVSSIIDIPSFLNEAFLRM
                     NGIDSLVSNAGISLHEGSFKNVTESGFDAQFKVNFKAPYFLAKYFVEKIENEKIDFANI
                     LFVTSERGSFCTSIPYGLTKASLKNYVGALCRYYCFNERIRVNAIAPGVTSSEMTGYSE
                     NGDFQTDDSPNGRIFHPAEMANVACFLLSDEASCISGETIHCDFGRHQSVID"
ORIGIN
        1 ataaagacgt ctccatcatt gggctcacgg tgaagccgtt cacgaatgac agacaacaca
       61 cggctgtgtt tacaacgcat atcggtaaaa tcacggacat aataaaaatg attcagaccg
      121 gtaacactca acataacccc tccaacttct ctaccatacg aaccaaatcc tggtagctta
      181 aattcttttg ggacaaatgc aagccattgc tgatacgaat cccaacccaa atacgaaccg
      241 ggtgatcatc tctgcttggt gataccggtt gaggttgatc actagccctg gatttttcct
      301 catgaccaat tgcaggagca ccatcaacct ggacttcaac tactttttta cgggtatcct
      361 tgtaccattt ctgaaagatg ttataaggaa ctttgttctt aacgcaaaac gattggagag
      421 attctccatg aggcaaagcc tcggtctggt attgaaagta aaacctttca agatcttcac
      481 tgctatacat aaattctaaa atttttgttc gcagcgaaga tagaggttgc aatcaatagc
      541 cattttttga ctgcttacgt tcctttctac gttcatcttc tgataaaaag tgtattttgc
      601 aatcagattc tatccagtaa agttcggaga tcaggttcac tacttcgaca gagcgttcat
      661 ccgtattcaa gcatctacaa attttcgccg cacatgcgcc atacatccat aacgggtaac
      721 tccctttcga tgccggtcaa aaagtttata aacattgtaa ccatccgtgg taatattacc
      781 aaaaaaatct ttgaaatggt tctcggcaac tgccatactg cggctacccc agtcatacag
      841 gtaataagca accttcaagg ccggattctt gctgccccag atatactgct tcttgtattc
      901 catctttccc gtttccttgt ttttgattct gaccagttca gtagtcccat cacagaacaa
      961 aaactgtctt tgctcaaaag aagattccgc aacggggttt cctgtttgcc caacagatct
     1021 gtgtgttttt gtatccaact cagtacagtg gaagaggaaa actttgcacc ggcatctgaa
     1081 aaacgagcta caccccgctc cgaagagagg ctatactgat atttatctac catgatctgt
     1141 gctatcatat ccatacctac atgatgtccc ggaagaacat tctcaaaggg gtgcaaggct
     1201 tcatcacctt caaacgaggc ataatagtta ctgatagcgc cttcggagtc aatcagtctg
     1261 ggaatttcga aaacatgctt acacacattc caatccattt tatacagtat ccaatgacga
     1321 acatcgattg ggcgggcatc agcagggact tgatcacggt tacagtagtg catcacggta
     1381 gattctatct gagtggcatt cttgccataa tccgaacggt ggggtttaga ctttgctgcc
     1441 tggcccacaa gagcatcaga tgatctcata gtatcaagga gggcatgtcc ctcatgagga
     1501 ggaagcccag ggggattgaa accatcaaaa tcatccttat cttctttcac gcttctttcc
     1561 tgtagcttct tcaggctttt aacctttcct gaactcctac cgtaaagttg ccgtttttgt
     1621 ctttcaagtt caaacaggtc atccgcacga gtttgctgca aagctttcaa ggcttccctc
     1681 agatcagact tttcctgttc agagttagcc aaacggagtc tccagacggg aacgttgatg
     1741 gcgtaactca tcatccttgg aaagtaattg agagattaat atgttgataa tatctttgtc
     1801 ttgcatgaag tgaatatact catttttaat aaattatgca aataaaaaac tgcgctgttt
     1861 atctgacaac caacatatta atcaacactc aaaagagcgt tttttgtatt cattttaacc
     1921 aaccaaaatc cctttacgaa cagtgccttg aagaagcact acaagcttat cccaactgat
     1981 ttcgtattgg tttaaatcgg aattgaaaac aggaagaagg aagcgttcac ggttcagttt
     2041 ctgccagtaa agcacatatc cattatactc atggcgcaga atctttatat tacgacggtc
     2101 ttttccaagg aaaataaata catcacccga ctcaggatcc ttatgcaatt tacggcgtac
     2161 caactccgaa agggtggcga tacctttacg catatcaaca aaaccttcac aaaggtagaa
     2221 attcatgtga gagctcaaac ctaacatacg cgtgacaaac tacttaaaag gttagtaata
     2281 tcttccaggt gggaatctgg tttatgaatc tcaatgccat tggaaagttt caaatgaaac
     2341 tcgctaacag tgcaaaaagc aatgggggga tttactggag cagtcaatgc cggagctccg
     2401 gtcactttga tagcactaat acgaatatca gccatttcac tttcgcgtaa acgtttcttg
     2461 ttatcacgat accaacggat aaaattgcgg tactcaacac cttcgcgcaa gcagaagcta
     2521 tcaatagata cgttcaaagg cgctgcctcg gtttgatagc gatataaaaa atcgctgtag
     2581 aattcagaca tgttcatgac ttggaataat tttaagttta agtcacgaaa gtaaaaatag
     2641 aagatataca aatcaagagc catacagtga gtgcttacat atcttagttt ttaaatcaat
     2701 tgcaaacaaa ttatgtacaa agcaccaact gccaccatgg cagcaagcaa tgtaatcttc
     2761 atcttcttac tcatagcacc aatatttaaa ggaattctgc ttcccccaac ttaaacggct
     2821 ccccgtgccc agggaaaacc atcatatctt tgtcaagtga ccgcaaatat ggcttggttt
     2881 cctgcttata ggctcttctg tcactccctg gcagatgcac tatggtcggt gtatgctgta
     2941 taagggaatc gcctgaaaaa aacgctgtct cacccaagaa atacaaggca ctccccgggc
     3001 tgtgcccagg tgccggatga catctcaaaa ccagttcacc tactttcaac ccacaatcac
     3061 cgtcaaatgc ctcgtctgca cgaagcatat accgcttagc ggtagccaga aagttctctc
     3121 ttctgtgtcc accgtcaacc gcatcacgta gcgtcagtat ataccccagt gtcttagggt
     3181 cattcccttt ctcagtggca atagcttctg cacaggcgcg atggcaaaac agtctcgtct
     3241 ctatcttcga ctgtaaccac tttacccccg tcgtatggtc ataatgctca tgcgtaagga
     3301 ctatttccac gctccttgtc cccagttcct gaaatactcg gagcaactct tcattctcat
     3361 ttgggtcaaa tacaatccca gtgtcccctg atggaataaa gaacatattg gaatccacca
     3421 actcataggg gaaccgatag attgacacct cgcgttcctc tataaaagcc ttataagagt
     3481 tcatactcag tgttcctcta tcatcaccca tccatttcgg gtgtgttcaa aggcatcata
     3541 cagcacctga ccggctttac catagtccga cgcttcaaac cagaacgtct tgtcttcaca
     3601 ctcgtatggc ttgatgatga cagggtacgt cacttttccc aataccattt tcgcctccgg
     3661 gtagttgtca aaacagaata tcttcttcgg tcgctcgctc atttcagtcc ctctaatttt
     3721 tcgttaatgt catatattag ttgtttggac ttctcccaac caaggcatgg gtcagtcaca
     3781 gactttccat acactcctcc atcaatgggc tggttgccat cttccagata gctctctatc
     3841 atcagcccct tcaccaattt tttaatcttg gggtattcct tcatcaggcc cagcacctcc
     3901 attgcgttgt ctatctgacg catatactgc ttgtcggaat tgctgtggtt gcagtccacc
     3961 accaccgcag gattttcaac attccttact gcgaaacggt cacaaatctc cgacaggtgc
     4021 tcatagtcgc agtttctggt tgcggcaccg ccttcttcca gataacctcg aagtacgccg
     4081 tgtgcatact cattgccctt tgacatcact tcccatccat tgaaaataaa atggtgcgga
     4141 tgctgggcgg tctcaatggc attcagcatt acgttgatac tgccacttat gggattcttt
     4201 aggccaacag gaatatttag tccactggcc accagcctat gctgctggtt ctctaccgaa
     4261 cgtgctccaa taacagcata gcccaacagg tctgccagat agtgaatagt ttcagggtac
     4321 aagagctcat ccgatgggaa caatccagtc tcttccacta cttgccggtg tacgttccgc
     4381 acagccgcca cacccatcga caggtcttca ccctgcccga tatagggttg gtgaatcata
     4441 cccatatacc ctttaccaat ggttctgggc ttgctggtat agacacgagg cacaataaga
     4501 atattctcga ccacctcttt ctgtatctct gcaaggcgtg cagcgtactc cagtacggca
     4561 tccatcctgt ctgcagagca aggaccgata ttcaatagca gtctttttga ctccccggag
     4621 aatatctttt ttatctcttt atcgtgctcc aacttctttt tggccattcc cttactcaac
     4681 gggtatatct tagccaattc ttccggtgta ggaagtttct tcaggaaatc cataatcaga
     4741 atgcgtttag ttccactttg ttgccaagtt ctgctgacat ataggctgca taaataatct
     4801 ttatggtatc atatgccaaa gtgaaacccg actgaggctc acggtcataa tacacgcact
     4861 ccataaaatc acgcatctcg tcagtatagc ctcgtattat ctcatcctcc aggaaggggt
     4921 tgttccatcc tgtcttggaa ggaagcatct ctgaaatata gacatcatcc aagttgtcct
     4981 catccaggaa gtaagtgctc atcaggttgg acatggtgag gttgcagttg atggcagcat
     5041 cgttacaata cagttccaca tagttcttcg aaccgccaag cagggtgtcg gtagctatca
     5101 ccacggcctt ggtgccgtcg gtaaagtcca gtatgatagt cccgaaatct tctacgtcat
     5161 gcggtctggc ggcaatatgc cggtgctcgt attcattcaa ttggggtgtg atccgatcca
     5221 tcacgcccag cacgctcttt actttaatct ctactccacg ggcttgggct tcctgctgtt
     5281 tcagccagag gatggccgaa agaggatgtg caccggtacg aatcatggtg ccaccgccgg
     5341 tcttgctcca ttctccggcc acgggcgaac tggatccctt caggctctcc tctcctttca
     5401 tgaacaggat acggctcttc ttggccttga taatctctgc ggtctttctc acggcagggg
     5461 catacacgaa gttctctgca tacatgaact tcttgccggt tttcttgata acagtgcgca
     5521 ggtagcgtat ctgctccaac atcttcagat acatcacgcg tttcggcacc ttgtcaccga
     5581 taggctcttc atcgccggga gttccgaaat agcccgtcag cggcttttcg catatcacgt
     5641 gcttgcctgc catcatagcc ttctctatca tctcctcgtg agcgtaggga ggcgtacaga
     5701 tgtctatgac atctatctca gggtcgttga tcatatcgtc aaagctgtac gaaatctgct
     5761 caaagccata aagacgctgg gcttcctcta gctgttcctt acgtcttgca acgatggtct
     5821 tcaacctgac aggcacacct aaaaagcgct tcaatgccat aatgtgcaat tccgtagcgc
     5881 gtccggcacc cgccattcca atggttactt gctccatatt cagatattta gtgttttgat
     5941 aatattcatt aactctttct gttctagtct tctttcctcc catttactgt actcgatagg
     6001 gaatacgaag tctatcctgc tgtcgtcatt cttcttgtcg tttttcatgg cttccaccat
     6061 attctatacg gtatagggta cgtcgtagta gagttggtag gcatccaccg cagcgcgtat
     6121 ctcatcaaca agcccggaag cacacagtcc cagatgacaa gctatcttag cctctcatac
     6181 cagtcccgtt gcaacagcaa caccatgtga aatactatag ttggagagtt tctcaatagc
     6241 atggggaacg gtatgtccca tgttcagcac tttccggagt cctttggtct cgtactcatc
     6301 ctgttccacc acgtcgcgtt tcatcttgat gcaactggcc accatctggt ctatacgctc
     6361 cttgattgtg ttctgtcgta tcatctccac aataccggca ttagctatca agtcgctctt
     6421 gatgacctct gccatgcctt ctgcaaagat gtctgctggt aggttggtta ccacttgtgt
     6481 gtctgccacc actaatgaag gttgccagaa agcgcctatc aagttcttcc ctgcctgcag
     6541 atcaacagct gtcttgccac ttattgaggc atcaaccata aagagtagcg tagtaggcat
     6601 ttgaataaaa tggatgcctc acatatacag tgcagcgggc actcccgtaa tgtcccctat
     6661 cacaccacca ccaatggaga ggaaaatgtc ctttctcgta aaatgacagg aagcgaaata
     6721 ctccaaaata cctgacagag tatttatgtt cttggaactc tctccgtatg ggatgacgta
     6781 tttacataca tcatatccgt attgttccat tgcccatacc gcctttgcag catacagggc
     6841 atctacggta tcatccgtga tgacccccac cttccctcct ttacagaatg gctctaccag
     6901 ccggggcaag tcagcaatga ctccctgccc caacaggaca tcctacttcc ttgaggtgtt
     6961 taccactatc gtttccacgc ttacttgtat atctggaact tatactgctc cacaaaatta
     7021 gtatcttttt tctttgtggc ggcaatagca tccctcggat gggcattggc cagtccggca
     7081 atcagatacg atgtattgta gccccaagtg ggctcctggt ctttcatgac caacatatca
     7141 cttcccacca agtccaacac gggctccaca tgatacttct tgccgttaaa atagccaagc
     7201 aatgcctcca ggtgacagtt gccagcacct cgtcccatgc cataataggt ggcatccagc
     7261 atcttggcat tcaggtcgtg tgcctctatg gtgttagcga aggcacactg ctggttgttg
     7321 tgggcatgga tgcctgtcaa tttgccgtag ggtgacaaat ggtcttggaa gtgcctggtc
     7381 agtttacgga cttccttggg atagagcgct ccgtaactgt ccactatata cacgcccatc
     7441 actggtgtct gggccagtgc atccaaggct ttcgacaact gcatcatcgt acattttgag
     7501 atggccataa ggttacaagt cacctcatag ccttgcttgg cggcaaattc tatcatctcg
     7561 atagcttccg aaaaggtctc tatataggta gccacacgaa taaggctcag cggactatcc
     7621 gacttcttgt ggatatcgtt cttgaagtca cagcgtccaa cgtctgccat gacacacagt
     7681 ttcagccccg tcgggttgtc acccacaatg ctgaagatgt cctcgtccga ggaaaatttc
     7741 cacttaccga acttactggg atcaaacatc ttcttgtctg cacggtagcc aaactccatg
     7801 tagtcaacac ctgcagccac attggtttca tagaccttct ttacaaactc atcggtaaag
     7861 aagaagtcgt tcaccagtcc cccgtcacgg atagtggcat ctactatttt tattccttct
     7921 atatttctca tgacggtctt aatgctgttc gtctatcttg gcttggataa aatcaatcaa
     7981 cttgcctact atcctcagtt taggattctc tatgtcctcc acctcaaact caatatcata
     8041 ctcgtcttcg atggtagaga taaactgaat gaaagccata gagtcaatat agcctgcctc
     8101 aatatagttg agagtcataa tatcgacgtc ttcaggtacg gtgtattcgc gctgaatata
     8161 ttctgtcacg aattctttaa tatctgtcat agtcgtaatt tctttttatt tgtctattcc
     8221 tacatttctt atatggtcta gtatgcggtt gcgctgcagc ttacccattg tgttcttcgg
     8281 tagcatatcc acaaagaaaa tcttgtgtgg ctgctggaag tctgccaggt tcttggcgca
     8341 ataggttttg atggtgcgct ctgtcagttc gcaatcttcc ttcaccacca cagccagtgc
     8401 cactacttca ccaagccttt cgtcaggata ggagaaagct gcgcattctt ccacagcggt
     8461 caactggttc actacggcat ccacatcatt tggatatacg ttgatggctc ctgtgataat
     8521 caactccttc ttgcgtccgg caaagtagag atagccatcc tcgtccatat agcctaagtc
     8581 accagtacgg aagaaccctt cggtggtagc catatccatc atgtttttca gcttatagta
     8641 gcccttacag gtcagcttcg acttcacggc aatctctccc acttcgccca cagcgcattc
     8701 ggtatcctcg tcgtcacgta gtatcttcac ttccgcttca tcaaagggca ggccaacact
     8761 cttttgcttg ttacgggcct tctggaagca aatatcagta gccgtagatg tctctgaggt
     8821 gccatacatc tcgtggaact cgcactgcaa acggtctatc agttccagct tcaccttctc
     8881 ctccagcagg gctgatgaag aaacgattgt gtggaagctg tctatacttt cggtattctc
     8941 ctgcttcagc agttcaagta tctgcgccaa ctgggcagaa accgcaatgg taaacgtcgg
     9001 tttctgttct gcggcacact tcagccacaa ggccggagtg aatcgtggca gcaggataga
     9061 ggtcgcaccc aaaagcaacg gcataatcac caggcgctct gccaaggagt ggtacagcgg
     9121 tgtagcagcc agtattctgt cttccttcac cagtccatac actcggatat gagccagcga
     9181 gcggtctatt ttgttctgct gagaaatgtc aattggcttc ggtgttcccg tagagccgga
     9241 ggtcatggtc agtatcaaac tctcatcgcc cttgatattc tcacaggcag gacgtgtagt
     9301 aggcatcgtt gccacctcac tgaaagggaa tgctccttca aactctccgt ctaggcatac
     9361 ggtgatgcca ggcacgtcca ctccaccttt cttctcgcat tcgttcagga aactcttgcg
     9421 ggctatcagg tgtttcatgt cgcccgactt catggccacc ttaattgact ccaaagggag
     9481 tgtagggttc agcggaacca gacatacgcc caggtctgcc gcactgaaaa acagcgcaac
     9541 tgactctatg ctattgttca tggggatggc cacatggtca ccatactgaa cacctttcgc
     9601 aacaaggtag ttcgaatagc ggctcacccg atttgccatc tcttgatagg tggctgtttt
     9661 tccgtcgcac cagatagcct gcttatcagg catctctgct gcgttcttat aaaacaaatc
     9721 tgctaactga cttctcatat taatcgtata tttgcagttc gggtatcact aagttttctg
     9781 tctcaaagca caagcttccc catgaaagac ccacgccaaa cgaacagccc acattggtat
     9841 gctttccgtt gcgcagtttc tctgcgcaac ctatcaccat cgtaaagggt atactgcaag
     9901 cacctgtgtt tccgaagtct ttcatcacta tgggtgcctt ctccgggtct atcttcagct
     9961 ttttgatgat tttcttcacc atatagaagt tggcctgatg gaagaagaag tagtcaatct
    10021 cgtccttttc cttacctgca aactccagca ctgcattggt gctcttgggg gcagtcttca
    10081 gggcaaagga gaacacatcc attcccttca taaaggtgtg cagacggttt cgcttcacat
    10141 tcttttcata ctccaccagt ttcagactcc cttctgtcac gggattcctg cgacctccgt
    10201 caggaacaag aatggcatca aactgtttac ctatggtgcc cagttcacaa tagatgggtg
    10261 ccgctgttgg atcatattct aaagcagtag cagtggccac atcgctgaac agcgggtagc
    10321 cggtcttgtc gtagtagcag ctctccgcag aaccctgtat accattgagt aacagtacac
    10381 gcttgatgca ccctgtctgc atcagtgaac aggcattggt catgccgtat gtccagcctg
    10441 tgcagcccag agtcatgtcg aatgccatgc acgattccgg caggtcaagc ttgccttgca
    10501 gcacacaagc cgtgtccggc tggatatagt ctttggaagg ggagccaaag atgagcaggt
    10561 ctatgctttc tttctcccat cccaactctt ccatcagttt ctcagcggct cgctgggcaa
    10621 agtcagcaca cgtctgacct tccttagcta catggcggcg ttccacgcct atacttggta
    10681 taatgttttc gaactcgttc tcgtcaaagt aaggatattc gctgttctcc tccaccttcg
    10741 atggtgcaca ggctgcgatg cccttgattc ttacgttgtt tatttttatt tttgccataa
    10801 tagtaatcct tgtttcaaca actgacggat aaccctccgt caataattac atttgttccc
    10861 gtaacccact tggctgcatc tgaaaggagg tatgctattc ccaatgcaat gtcttcaggc
    10921 tgtccatagc cgagaggata tttttttgca tcttcactca actgttcatc agtaatgcca
    10981 ccactatgaa taaggggagt gtcaacagtg cccggacaca ctgcattgac cctgattctc
    11041 tgggcactca attccagtgc agcattctgg atgaaagcac taatggcacc tttagatgca
    11101 ctgtacatcg tattaccggg tgtgcctttt ccaagtgcag ccatgctgct tgtgaataca
    11161 acagaagagc ccttgcctaa tattcttttc ttaagtagtc tttgcaaaag tagaataggg
    11221 gaaaccgtat ttacttgtag caatccttcg agactatctt ccttaataaa tttaatagga
    11281 gctattattg tagttccagc attgctcaca aagccttgta ctggaggaag gcttgcaaca
    11341 aagtcattca gtttctccgt ttcagacaag tcgaaacaaa tcatctgatg tccttcaccc
    11401 tccagcgtat caagcgtttc tttcagccta tcctcattac gggctgtaat gacaaccttt
    11461 gctccaagct tagcacattc gatagccgtt gcacggccta tgccggacga agcaccggtc
    11521 accagaatgg tcttccctgt tagagaatat ggattataca tattgtttat gctttggctt
    11581 ttatagcgtt gaacaagtcc tcaacggtat tggaattcca gatttcatca cccttgatgg
    11641 taatatcata ttcctcgtcc accatagcta tcacgctcag agccacaagc gatgaccact
    11701 cgtccagttc cttaaaaacg gtgtctgcct taatctcgct ggcatcggtg tcgtcaaact
    11761 gctctgcaaa attctcaata aattcgttta attccataat tttcaataat tcaattatta
    11821 ttacttgttt tatttaatat ttcaacagtt tggctggatt accgaaaacg gtagttccag
    11881 ctttgacctt tctaaccaca aagcttaatg cagctaccac tgcatctttc tccactacta
    11941 catggtggtt caatatggca ttggtatgta tagttacatt ttcttctatt cgtacgcctc
    12001 caacaagaaa tgccctgaca tcaatgcggc aataatcacc aaccctacag tcgtgaccaa
    12061 ttccagcaaa cgtctgcacc aaacaattct cgcctataat cgtatctgat cctatgtggg
    12121 cgtgactatc gatgatacac ccatcaccaa gtttcacatt ttctcccaat tgggctgtct
    12181 catgtagcaa ggtaatgaac ttcccccccc tgtcttttat catttcgcag agcgttctct
    12241 ttgttttcac attaccgata gagcaggtaa atacatcatc ttctgaaggc tgatagttct
    12301 ttattgtatc taagactggc ggatacccct cacaaccatc caaggaattc agattgtcat
    12361 ctatgaatcc ttttatgtca tactctgttc cataaccaat ggaatgcttg gctgaatggt
    12421 aaatatcctt acccattcct ccgccgccta ttattaccaa atgtttcatt atgttattcc
    12481 atattagttt gtcccatcaa atgtctctac tgtagcctga cctttctggg atattccttc
    12541 tcttttgaaa attttaacaa tggtcataaa gaatattttc aggtctaagc caaaggtcag
    12601 atgatccaca taatacacgt catactcgaa gcgctcggta aaaggcaact cattacgccc
    12661 gtgtatctgt gcccatccgg taatgcctgg tcttacctcg tgacggcgca tttgctcagg
    12721 cgtataaagc tccagatatt ccggcatcag aggtctgggg cctatcaatg ccatatcacc
    12781 tttcaacaca ttaagcagct gtggcaattc gtctaatgat gttgagcgta ctatttttcc
    12841 cactttggta agcctgacct catcaggtaa cggttcgcct ttttcgtcaa actcatcctt
    12901 cattgtttta aacttgatca ccttgaatat ctcagcatcc ttaccgggtc tggcttgaat
    12961 aaagaatgct ccagcccctt tgttggcaaa atgaagccaa atggtcacag ccaacaatat
    13021 ggggctaaga caaatcagag cgaccaaact gataataaaa tcaaatggac gtttaaagaa
    13081 gtgcttatac atatttatat tttttctccg cattcaataa tttgccctcc atcacttatc
    13141 acaacgcccg tcttaataac taccgcagga ttgccggcta ttatggagtt ggggggggca
    13201 tttttggtta caacagcacc tgcggctaca acgcaatgat ctccaacggt tacaccgggc
    13261 agaatgatac tgcgaatacc aatcacacaa ttctttccaa tccgagtgtc aaataacctt
    13321 cctttcccat ttttgcctct gcagtgatca tatgccagaa taatagcatc tctcaacacc
    13381 catgtatttt taccaatatg aataccttgg gggttaatgt ttttatccag aactgcggtc
    13441 cgtgctatta ctgcattctc acctatatcc atcttaaaat gccatttaag atatttgggg
    13501 tataaagatg tcatcttacc ccataaccaa gcacgaagat taaaagaatt atttttatcc
    13561 atttttttat atccatttca ggctttcaat gttcctgcaa tattgactct ttccttatta
    13621 aaaatataca atgcaagata tactcctatg taaaagatta aattatgata ataagtcaaa
    13681 tcagcaaaaa acagcaatcc cgtgtataga gatgtacaca cctttacaaa gatgtccgct
    13741 ttgattatta gcatgccaag gaatagtagc aatagtgtcg ttcctatcaa accgtaacag
    13801 tataatagtt tcataaaacc cgtaaaatag actccatcag gtaaattatc caagccaaaa
    13861 cctgttaaaa aatcagatat attaaaatca ccaaaatatg tatcccacca aaacagcctc
    13921 ccattaatgg cattataatc atcacctgag gttgaagtaa aacggtttat aatattatgt
    13981 gtaaaactaa tattgtctaa taaaaaaaac accaaaaaaa gtgcgataag gattacaggt
    14041 aaactcctga taaagttttt cttagttttt tgccttgaaa gagcccaggc cccccaaata
    14101 gcaaacactg aaacaaatcc cattcctgaa gtacttgcaa atataccaag agaaataaaa
    14161 agagcattct tcgtctttgg tctatgggta aacaaacaag acccaagacc gattgtacaa
    14221 tattgtgaat actgtgcagg ttctaagaaa aatgcacatg gcctatacat tccctcaaca
    14281 gctccggtag taatcgcatt gttgtattgt tccaacaaat catttgcaaa aaaaggaagg
    14341 aggtaaaaat ggaaatgtat gcctgtcagg atatgaacga tttgctggaa gattacacag
    14401 aatgcagcga caattgcgac cttttccagt acttttctta ataaaaaaac atttactata
    14461 cctgtacaga ttgccgatat aataattatc acactgccgc aaagaaatgc aagttgtaaa
    14521 gaactcttaa acatcacata tgtcaagtac atgaacaatg gtaataacat ataaattggc
    14581 actctcatat gcctattggc taactgcaag agagaataca acattgcaat tgctgtcaaa
    14641 agcgtaggaa tccgtattcc agtaccaggc acactgtaca tcattactaa cgggagaaat
    14701 aatagataat aagtgaacca cttactggtt ttaacaggta taatcatctt attaactaat
    14761 cagttctttt aacatgcttt caagtctctt tgcctcatgc tgtatattgt aacaatctgg
    14821 aactattgca ttggttctat cataagattc acagcacgaa tctaaaagat taacactttc
    14881 agcagcccaa tatgcaggtt tttcgctaag cggtaagagc tttattctat cagaaattac
    14941 tgcctctttt ggtataacga cttctgagga aacaacggca aggcctgttg cttgagcttc
    15001 aacaagtact attcctaagc cttcaaatac tgacggctgt aacaaaagat ccattccttg
    15061 catcaatcta ttgacatcct ctcttcgtcc aagccatttt actgatgaac atatcccttg
    15121 ctcgtttatt tctacttcca tttttcctct caaaattcct tctccaatta tccaaagctc
    15181 actattcgga cgaagtttat gaatttcagc gaagacttta agcatgaaca aaggattctt
    15241 ctggtctaca agtctaccaa caaatcctat taccgtcttg ctctgacagt ccaattcttt
    15301 tcttatacaa tctctatgtt cttgtttaaa agcgaacttc ccaacatcaa tagcattata
    15361 tataagcttc gaattaacac ccttcccaaa catataatct gaggacaact gggaatttgt
    15421 gaacatcaca aaaccacaga atctcgaaag aatttttcct aaattgtgtg ccatcaaata
    15481 cattcttccg cctttctgta gtccattatt atgagcatgt aaaattacct tatatcccct
    15541 aagttttgca ataacatctg gtatgaggtt agacattgta aatagttgat gatataatat
    15601 atttgtgcca gacttcttct cttcaccaaa aatacgccac aatttgttta tatacccaag
    15661 aggatgtctt cttacccaag gaacaaaaaa tatttttcca cctcttttcg ttatccgttc
    15721 tctatatgca cattcatccc cgtcaacaat ataatcaaac acacaatcat cagacatgta
    15781 ttcgctcata ttgagggtat atacctcaat cccccctaaa acgtttccgg taaaaccgta
    15841 tattaataca cgcattaatc gaataatact aaaagattat attactttta tctatgtaag
    15901 aattttttta tcgcatattt agtcctacaa tctaggaact tgttaacgaa cccagctatc
    15961 agcctttctg gtgtcatttt tatattattt cgaataagtt ttttcaagga agaaccatcg
    16021 agttcagggt tggtaaagac ctccattaaa attggatttt cactttcccg caaaaaaagt
    16081 gaaagttttt cttctaattc gcctttatta tgaacagcta tgtattgaaa attagataaa
    16141 ctaatagcat cttgtatttt tgtatgatgt ccagccgcta tatgctgttc aagtgtggat
    16201 atttttttct tcccaatatt aaaatggaat tcgccccccg caaaattatt aatgagtaaa
    16261 actctagtgt tatttttaaa gtcatggata gctgcattta gatcatacaa atagctcaaa
    16321 tcccctataa caagcagcga gagactatca agcacttcgg cttggccaat aaaagtagag
    16381 agagctccat ctattccatc tgcacaattg ttacctgttg caatagtatt ttgtgggagc
    16441 ttactcatat ttgtgaattt catactattc agaacacttg catgaacatt actgccttcg
    16501 ggcaaagatt ccaaaacctt ttttgcaaca taataattag taaattcatc tatagaatta
    16561 tctcggcttt cattcaaagc cctccacaat ttatcatact gcttatcgtt tgtcgtgata
    16621 ttataggaaa ctttgtcaaa aaattcctct ggagtaaact cgaatatttt agtaagcgac
    16681 ctgcttgtgt caaaaatacg accttcaaaa ttgatttccc agtgttcaat tcccattccc
    16741 gcaaaacgtg agacaatgtc tgagaaatat tttgttccaa atgtaataat aagatctggt
    16801 ttcaaactta gcagttcctt ctgattaagt gttattgaca acaacattgt ttgaataaag
    16861 tctttgtctg caacatttga aaacgcatca aatgataccg cacaattata tttctcataa
    16921 aactttctta tacttgacct taaacaccct gtaaactcct gatactgacc acaaacaaca
    16981 agaattcttt tttttgctgc aagtacattt ttccactcat taatttgtga ccaatcctca
    17041 attctattta tttttcgaca cacaggcata ttaccatcgt aaaagatgga tagttcatca
    17101 atgctactgg gctctagaaa gtttatttga atagggcctc ttccatgatg atccatttct
    17161 aacaatgctt cattaataca acgattgcag aaccattcat ccatggaatc attcacttcg
    17221 ggcaaatcta cagcatatcg acaatatggt gcgaacatat caacttggtt tattacttga
    17281 ctaacaccat gaaatctctg atatctttgc ttgtctgaag ttaatgctac caactgaata
    17341 tttctctcat aagcctcctt catagccggc atataattgc atgatgcagt agctgatgta
    17401 caagcaaaac caacgggttc atctaatgcc tcagagagtc caagagcaaa aaatgcggca
    17461 cttcgctcgt ctacgataga ataacaccta aaaaagggat ccatttcaac aatatgtaca
    17521 aaggccacat gtctcgtccc tggcgaaagg acaaaatgtc gtatattatt ttgttttaat
    17581 aatgatacaa tctgctgtac ctgttttatc tttgtcttca taacctctat tttactaaga
    17641 ttgcataatt gggcttaaaa ttcattgtcg tatattcaaa cgaacgaccg tctacaacat
    17701 atgtgttgat gttattcctc tgcatccaag tattaagacg cccccaacaa acaccgtcgg
    17761 agtattttac aattaatttg aaaccgtcag gaaaatccct gaaattaaat atatttgtat
    17821 ccaatgccaa taagtattct ggaatacata aaaccgattg ctttcctcct ataagttgtc
    17881 ctacatattt tgaaataaca ccatatttat actctggtgg tataaattca tagtctttat
    17941 taccatattg aggattataa cataaaactt ttttatcctt cgcgcacaaa tctataattg
    18001 aaaatagatt ggtataatca atcttttttt cttcgtttac ctcctccttt atttttataa
    18061 gagaaggtcc atgatgttga atagcattac atactacacc ttcaattgtt tccacattat
    18121 cgattaggat agatgcatca acgcacctat tcaaatagaa cgaactatcc aaattcatac
    18181 tattcaatgc caatacaatc acttgcactc tttgaagcca tgcttccgtg agtgcagtat
    18241 atgtattagg taagtaggcc tcctccacta taatagcaac tggagaatgg ctaatctttg
    18301 acattccata tgcgttaaaa acagcacttc taacatcttc aatataatac cattctatat
    18361 tggaagggta tgatattttt tcttttatct gtgtagttgt attaacaaat cttactacac
    18421 ctttagcgtt taaacacgaa ataatgctat caatcataaa aaacctattt gatgttcatg
    18481 tttttcctat actaatcgat tacactctga tgtctcccaa aatcacaatg aatagtctct
    18541 ccactaatac acgatgcttc atcactgagt aagaagcaag caacattagc catttctgcc
    18601 ggatgaaata tacggccgtt tgggctgtca tcagtttgaa aatctccgtt ttcactatat
    18661 cctgtcattt cagacgaagt tactcctggg gcaattgcat ttactcgtat acgttcatta
    18721 aaacaataat aacgacacaa tgccccaaca tagtttttta aagatgcctt agtaaggccg
    18781 tatggtatag aagtacaaaa gcttccacgt tctgatgtaa cgaatagaat attagcaaag
    18841 tctatctttt cattttcgat tttttcaacg aaatatttag caagaaaata tggtgcctta
    18901 aaattaactt tgaactgagc atcaaaacca ctctccgtta catttttaaa agagccctca
    18961 tgtaaagata tacccgcatt actcacaagg ctatctatac cattcattct taagaacgct
    19021 tcatttaaaa aagatggtat gtcaataata ctagaaacat caaacttaat atattgacaa
    19081 gattcgccta attcccggca ggctctgcgg agagtttctt cttgccttcc gcaaatcaac
    19141 acttttgctc cttcagatac gcattttttg gcaatccaat aacctattcc cttgccacca
    19201 ccagttatta aaatttttct tccttcaaga cgtcgtgtcg taaaattttt taccgcaata
    19261 cttatatgcg gccgtggtat tccccgaaaa atgtatctaa acgccctttt aacaattgct
    19321 gtattcatac aatatttcca aaaatatatt tataaaaatt gtcatactct tgtctataag
    19381 tcgataagac gtcatctaca agcgaataat ttatattatt attatcaata tgaattgtat
    19441 tgtatctatc ggataaattt agtaatgcca acaaatctgt tattcttgat gactgagatt
    19501 gtttatgcac atattgccta tcaaacacat aaaaattttt atgaaataat aaagcgaaca
    19561 ctgtggcatg aaaggaatcc gtcatcacat attccgcccc atcaatcata gaaagaaact
    19621 cccatggtcc accatctata tgattctcta tgtttttttg catgtaaccg aaactaacaa
    19681 catgatatcc tgtctgttgt gccaactgca ttgtggagtc aatagctaaa accgaagg
//
