LOCUS       gnlProkkaPBKCDDFI_110  32541 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PBKCDDFI_110.
ACCESSION   gnlProkkaPBKCDDFI_110
VERSION     gnlProkkaPBKCDDFI_110
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:18:07
            Original ID  :: gnl|Prokka|PBKCDDFI_110
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 22628
            Orig. end    :: 55169
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..32541
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:22541]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..22541
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..32541
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..32541
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(1063..1863)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 117.2; E-value:
                     1.3e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_19"
                     /transl_table=11
                     /translation="MKVVLLAGGFGSRISEESQFKPKPMIEICGMPILWHIMKEYAYYG
                     YNEFIICAGYKQEYIKEWFANYFLYNSDVSFNFRNGKNEITVHHSNLEPWKVTIVDTGY
                     NTLTGGRIKRIKEYVNNETFMMTYGDGVCDVDINKLVAFHKKHGKIATLTAVIQAQDKG
                     VLNIDENNSIRSFREKNINDGVPINAGYMVLEPRVFDYIEGDQTIFEKEPLNKLATEGE
                     LMSYTHKGFWQCMDNIREKNLLEQLLIDGVAPWKKWEREIPIIK"
     CDS             complement(1860..2336)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_20"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 2.4e-09,
                     bitscore: 30.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNITIDGVLLTPLKQITHPKGDVFHAMKCVDPGFEGFGEVYFSS
                     VLQGLVKAWKRHSRMTLNLVCIVGKIHFVLYDGRENSSTFGKYMEVILSPELPELYRRI
                     TIPAGVWMGFVGIGEGKSILLNVANIPHDPLEQVNIPIEESDIKFDFNKISRSI"
     CDS             complement(2346..3446)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     100.7; E-value: 1.7e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_21"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.4e-10, bitscore:
                     31.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5e-14, bitscore:
                     45.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFSNIYKNKKVIITGNTGFKGTWLSTWLKMMGAEVYGYSIGVPT
                     TPSMFDTLHLEDKICQHYGDIRNKREFNDFVQEVKPDFLIHLAAQALVLTSYREPFETM
                     TTNIVGTAVVCEAVMNIDWNCTCVLITSDKAYDNVEWIWGYRETDGIGGKDIYSGSKGA
                     AELVIKSYWHSFIKKMPNIKFGVARAGNVIGGGDWAKDRIIVDCVKAFSEGKTVEIRSP
                     KATRPWQHVLEPLSGYLTLAQYLCEGKCENGESYNFGPRAEQTKTVFELFQDLATLWGL
                     DKNKAAKLTGNVPFEEATLLKLNCDKALAYLHWHSTLHYDECVNFIAEWYRAFYVEQAK
                     DMFALTEKQINAYMEAAKKQNLDWAK"
     CDS             complement(3436..4698)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     162.8; E-value: 2.2e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_22"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.3e-52,
                     bitscore: 172.4, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRLLFTSEISSFISPSIDISEKQSDYEALIEAPNLDYVNRYEKE
                     LSQFLGGGHVVTFASGRMSFYSLLKSWGIREGDEVALTGFTCAVMANAVLRTGATPIYV
                     DIDKDTLGMSAESLVSKITNRTKVVVAQHSFGIPCKIDKIKEIAKSHSCYLVEDCALTF
                     GSKYKSIIVGNYGDAAIFSTDHTKPLNTLIGGFVYTNDIDIATSIRAMRDDCGDLSNEH
                     QRMILKTYIDEHRIETVNHKIYIMRNYKKALMNKLHIHNEISPYLELETSAKIAINPYY
                     SYPAKLPSVLAKIGLHVLEQYKANIHQRQSWLKEILQVVEKKEDMPAAYYDTGCDIIPL
                     RIAYSTYFALTVFSYIDDWIWFKTPIVATKENICDFGYHWGGCPVAEKIGKSIMNLPVI
                     IDSKQQNIFLRNIKKTYSYGI"
     CDS             complement(4762..6291)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_23"
                     /sec_met_domain="Polysacc_synt (E-value: 1.4e-08, bitscore:
                     27.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISYRGKYFRIYIWQGLSIILGFLSLFIVMPLLSGNKTLFGIYS
                     VCTSLTIFFSYADLGFISSGLKYAAEYYIRGDRKNEIRTIGFTAFIMLSMFMLIALLFG
                     IISIFPQILMPELEPDRENFYTARYLLILLSVSCPVIIGQRILNMIYSIRVEDYKLQRI
                     SAVGSILKILSVFFFFGSENYLLVPYFAFVQFINLSVVLMAAFQVRKYQYSFVEFLKAI
                     RFDRIIFDKEKGLTGASFISILSWVLFYEFDQIAISNFVGLEAVAVYGIAFSALTFVRT
                     FVSLLYSPYSSRYNHLIGENDRVGLMKFVNRMLLMLSPMVVLPIVGLSMLSEPFIISWV
                     GFNYEESSSILSLLVFCFFPCFLSNPSSSYFIAIEKTTLLNRFNIFQPILYWLLIFFTI
                     DKWGVFSFAISKGLIPIFLGILYWYSLYRDFAKNAGQIVSLFLILKTLFLPLIVLLVLS
                     TLVKPYMAYEYNKISLCYNLLVMGLIVLISILVSVCCNREMYSLVKSIIRR"
     CDS             complement(6297..7940)
                     /locus_tag="ctg73_24"
                     /transl_table=11
                     /translation="MILNLNELTLEQSKLKAKLKKNVIADYNALTEQLIDYNRDSLEWL
                     VCNVNSRSTVFSSMLAELESLRLISELISSGEIIEEIIVDNDELRKTISNLYPKINVHG
                     KTSSLKNNIRLWKNNIRYGIWSLCSWLSGSKERRNKVCRGGRLTIIDTFIAKKVDAYWD
                     RFYGNSVDKLIDAQKEQIYFMPLYLPFASKKQLDIIVANSKENLFFMSDFLLFKDYLYA
                     WRYMGRFEKPDFASYTYQGFSLQWLLGKAYKESNQSYFYYAILMERAIMRMKELDVDIC
                     LFVDWFENQSYDKSVYYAMHQYYPEAKVHGYMGFIADSTIFPHIIASNKELFCHIAPKD
                     IYLCSSYLLKFYQNYNGYKHIAPALRNQEIYSSHRSTKPHDKFTLLVPFALDNYDMEYK
                     YELLTDFIKSSNANINILLKPHPDANSSWMVSCTNKAGGKLEVVKGNVNSFLLKADAIL
                     AANTSVMFEALSLGIPVINLKDPLSIILFDKIEEVNEVLWYTANNLAELSDAIVRILNL
                     NIEDAMTEGYRLRNYFFTKLEPQLIFQLFT"
     CDS             complement(7941..9098)
                     /locus_tag="ctg73_25"
                     /transl_table=11
                     /translation="MSNQNLPKLFFFNIEPWKEVYNDRFLLKQLQEKGFPIEYVWIGPL
                     VGLLSNVSSKGCETIPKSWKEIQRIINLDRNKDAILISLMPVFAPCLKLFRILSKAKQK
                     NVGYFNIGSMHLPLPKNRMEHRLKLLFNPIRVRYYFIHRSIPLLRKIGYLKDFDYAVTQ
                     GVHSINSASQLISDKTQKITIVDYDIEHFNKVDKMERYNDRKYIVFIDAYMPFHPDFEV
                     TASGHIDPEQYFKSVNNYLKRVEDKYGLPVVIAAHPSAQKYHEHNYFDGRPVLFGKTAE
                     LCKGCAWAINHLSTAITFLIIQHKPIKFITTDEVVNKYGIAAELSYSGFFQSPLVNIDA
                     EDADISVPVVFDSVYDEFIDKYLYTKDEIGKASADLLSEALLKIK"
     CDS             complement(9316..10008)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207:inositol monophosphatase (Score: 61.1; E-value:
                     2.3e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_26"
                     /transl_table=11
                     /translation="MNEPDICRSIHELIMLHLPEILSLRNTSELKSDHTFVSKGDKLCE
                     KLIFDFLDSNLKDYLVISEETETNLSRLEEVEYVITVDPIDGTENFVSGLKEWGVGISV
                     YKGMRHYQSMIMLPELGIRLCTGDQFSKIIGSRICGLSSYMQPEDFKRLEQGSEYRIMG
                     CCMYNMYNVIRGCYRQFLHLKGCYSWDILPGMNLALEQGLDVELEGEKYGGEFLYPGVK
                     YRFNIKAG"
     CDS             complement(10001..11578)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 64.8; E-value:
                     1.2e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_27"
                     /sec_met_domain="HMGL-like (E-value: 1.8e-22, bitscore:
                     73.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIQLLDCTLRDGGYINNFRFGKYAIRKILQQLTHAGLDIVECG
                     FLEDGEYDEDTSIFNAAEQIASLLPNEHGRTMFVAMVCYGEYDLSQLSPCTRNSIDGIR
                     VTFHYDEVEGALEYCREIKEKGYKVFVQPVGTSSYTDIQLLHLIEKVNELQPYSFYLVD
                     TLGLMHKNDIARFFYLINTNLDKSINMGFHSHNNLQLSFSNSQEFFEYVGDRVISLDAS
                     IYGMGRGAGNLNTELIANYVNDREGHMYAIEPLLEVVDEFIIHIRQKHEWGYTVPYYLA
                     AINGCHPNYASYLAQKQTLAVKEISAILHMIPVEKRSLYNKELVNRIYLEYQSHEVDDT
                     YVLKNLKEKIGGRNIILMAPGGSITDCYDEIVQKQNSENCLLISVTFVPDFMDCDFTFL
                     ANAKRYATTFNPMKKEVSLIYTSNIRANQEQSGYCVNYVSLLNEVDIIRDNSALMALNL
                     LQKLSPRKVYLAGMDGYSMKKGNYYQERLNLIQDRDYVLEMNKAIKHRISEIGKVMDIE
                     FLTPSLYE"
     CDS             complement(11575..12327)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_28"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.2e-14, bitscore:
                     46.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIAVIPARYKSTRFEGKPLVNLCGKPMIWWVHHQLCQVKGLSE
                     IYVATDDERIGKVCSDYGIKYVMTSDSHPTHLDRLAEFAENIESDFYININGDEPLMMP
                     EYVERLLPTSDLNPADFYFANAMTKIKKTVEVADISRIKVVTDNLGYAMYMARTPIPYP
                     KASSDFDYMKFVGIQCFSRSALLFCKDNKRGKIESIEDIDEYRFLENGKKIKFVEIPAE
                     TLSVDTQADVKIVTEVLERRIKNKEIVL"
     CDS             complement(12347..13387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 145; E-value:
                     4.4e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_29"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.3e-11, bitscore:
                     38.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHSHIISQSLSIIDSIRCINEIHGEPLVLFVVDAEKRMQGTLTD
                     GDVRRALIKGIDVDAPISEAMHRNFNFLRRGVNDGVEDIHRQRDLKMRLVPVLDEENHI
                     CEIINLEHYITKLPIDAVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLLSYG
                     LNHISVTVNYLGNQIEEHFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNS
                     DLFTNIDFEDFFLHFCQHDADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYAN
                     AGIYLIKRKLFDLIPDDIFFNATDFMDKLIEQGYKVIRYPISGYWLDIGQHDELARARE
                     MVKHLK"
     CDS             complement(13398..14087)
                     /locus_tag="ctg73_30"
                     /transl_table=11
                     /translation="MNILVIIPVRGGSKGIPGKNIKILGGKPLIGYTIDAARAVTDNDH
                     ICVSTDDDRIIQVVEQYGLKVPFKRPEELATDTAGTYEVLLHALNYYESKGETFDVVVL
                     LQATSPFRTGNHIKEALKLYSKEIDMVVSVKETDSNPYYICFEDDANGMLHISKGDGHY
                     TRRQDCPPVYEYNGAIYIINPDSLKRMPLYKFTKRVKYVMDRGHSIDLDTMIDWQIAEY
                     MINNHLI"
     CDS             complement(14092..15246)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_31"
                     /sec_met_domain="Epimerase_2 (E-value: 4.1e-88, bitscore:
                     288.8, seeds: 187, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKICVVTGTRAEYGLLSRLMRLIDESADCQLQVIATNMHLLPEY
                     GNTYQEIECDGFHIDAKVPMRKLSDDSYGVIDSMAEEMKGMNEALLRLHPDMVVILGDR
                     YEMLVTATVAMLQRIPIAHLHGGEISEGAVDDSIRHAITKMSSLHFTSTEDYRRRVIQL
                     GEQPDRVFYVGAIGVENLKQIPLMSRQDLEDSLNFTFDRKIILVTYHPVTLGNRSPKDE
                     IDDFLFALDTFPGLKVLFTMPNSDEGSEVIRQAIEGYCSRNSDRCSCYSSLGLKRYLSA
                     LQYVTAVVGNSSSGLLEVPSVHIPTLNIGDRQKGRVHGNSVLDCASDKESIIRGLTMVL
                     SLSFKEVALKASNPYEKENTVQSVFDVISTYPLDELKRKSFYNL"
     CDS             complement(15243..16250)
                     /locus_tag="ctg73_32"
                     /transl_table=11
                     /translation="MKHTLIIAEAGVNHNGSLTIAKKLIKVAAEAGVDYVKFQSFKAEN
                     LVTKSAKQAEYQQHNIGDGNTSQYNMLKKLELSHEQHVELLTYCREKGVKFLSTAFDFE
                     SIDYLASLNLGFWKIPSGEVTNYPYLVKIAQTGFPVIMSTGMCEMEEIQSAFDVLTAHG
                     LQKEQITLLHCNTEYPTPMYDVNLSAMNEMRSQFGVSVGYSDHTQGIEVPIAAVAMGAE
                     IIEKHFTLDRSLPGPDHKASLEPDELKAMVTAIRNIEQAIGMGYKTVSASERKNKAVAR
                     KSIVAARDIKKGELFTEENLTVKRPGNGINPMRWPEIIGKRAVRDFNEDELIEI"
     CDS             complement(16250..17152)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 171.8;
                     E-value: 2.7e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_33"
                     /transl_table=11
                     /translation="MKKFRIGYFADGLWGHFTLDTLLKDETLEIVFIVPRNDTKDEYLK
                     NKALEYGIDYLMPVKVNSEEFYQKAINYGCDLFVSMSYNQIFKRKIFDLPPCKTINCHA
                     GKLPFYRGRNILNWVLINDEKEFGITVHYVDEGIDTGDIILQRTFPITDADSYNTLLQV
                     AYEACPKILYQAIKDIQAGKAKRVPQDMISHHGLYCGMRQIGDELIDWQMTSRELFNFV
                     RSICQPGPMATTFCKGIPVLINQVEYNENYPQYKGIPGQVIGLEHACPIVKTKDSYIKI
                     VQYESECKLKVGDRLQTNQ"
     CDS             complement(17170..17379)
                     /locus_tag="ctg73_34"
                     /transl_table=11
                     /translation="MKRPLILVGGGGHCKSVIEAAESAGYLIKRILDIPSQVGEEVLGY
                     TIIGTDNDSMYCSSMNTLSCEKAA"
     CDS             complement(17387..18532)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     270.3; E-value: 4.7e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_35"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.7e-88,
                     bitscore: 289.8, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNAEICEFIHHLFGTQDFVPLSAPKFIGNEKKYLNECIDTTFVS
                     SVGAFVDRFEHDMAVYTGAKRAVVCVSGTNALHMAMLLVGVERDDEVLTQALTFIATCN
                     AVSYIGAYPVFIDVDKETMGLSPRAVKAWLERNAELKEGVCYNKRTGRRVKACIPMHTF
                     GHPVKIDELADICREWHIELVEDAAESIGSFYKGRHTGTFGKVGAISFNGNKTITTGGG
                     GMLLFQDEELGAYAKHLTTQAKIPHRWEFRHDHIGYNYRMPNINAALGCAQLENLDRYV
                     ADKRETAARYVEFFKGKEDITFFTEPADCKSNYWLNAVVLKDKVAQLEFLEYTNDHGVM
                     TRPVWELMNRLPMFEHCETDGLENTEWLADRVVNIPSSVRL"
     CDS             complement(18554..19384)
                     /locus_tag="ctg73_36"
                     /transl_table=11
                     /translation="MHIGGGHSDKLPPHAVLLSFDDAYADHFEYVFPILEHEHIQGAFY
                     PPVKAVTEHTVLDVNKIHFILASTPEDNFPVLLNEIKQLILANTDEFGLKSYDEYFKEL
                     AVANRFDPAEVIFVKRLLQVALPEALRKRMADILFEKIVGIEESAFSRELYMSVDQIKC
                     MVDCGMHIGSHGYDHYWLGSLPREKQEFEIKKSIEFINEVGGDVDNWTICYPYGDRNKE
                     TIQLLKENGCKLGMTTDVDLADLTDHEGDAIFNLPRLDTNDLPKDANAPVNQWY"
     CDS             complement(19362..19544)
                     /locus_tag="ctg73_37"
                     /transl_table=11
                     /translation="MNADKLTVVMYHYVRDLQNSRYPQIKGCDVRLFKEQIKFLQKHYN
                     FVTIEQVINAYRGGA"
     CDS             complement(19562..20596)
                     /locus_tag="ctg73_38"
                     /transl_table=11
                     /translation="MESVYNIKQVPTCEVNKLVHFINMHWKHNHSLAVSRELLNFQHLD
                     KDKDCYNFLVAENKETGEYDALIGFIPVAQYDKDLVGNGDYWGAIWKIRDDIYNSELNT
                     VAFFLWRSLFKLPYFHSYAAIGISDIARQIYKVSRIPVDYLRQYYLRNSRIKNYQIAFF
                     PVGSQNGSAISDESYTLQLVHNVEWDKIAIKGEYAPFKTPLYFCHRFAEHPVYHYQFVE
                     VKKNGILESVWTVRIMRVGDSSAFRIVDVLGKLPNTCVKGQLLDILYQTGAEYMDFMNF
                     GLPEETFTKMGFELLDLDGETIVPNYFEPFEQRNVKIEIAYKTKGDNYVAFKADSDQDR
                     PNIL"
     CDS             complement(20608..21330)
                     /NRPS_PKS="Domain: PKS_KR (2-166). E-value: 1.8e-07. Score:
                     23.0. Matches aSDomain: nrpspksdomains_ctg73_39_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     156.9; E-value: 1.1e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_39"
                     /transl_table=11
                     /translation="MNFLVTGCSRGVGLEICRALLQQGHIVYGVARSYTNEFKFLETEY
                     AGRVFFKSIDLSDSENVRKTVFREFIHNGIQLHGYVNNAAMAYDDIVTNLNLEKLQAMY
                     AVNVFTPMMITKYALRNMLLHHTKGCIIHISSISAHTGYKGLAMYASSKGTLEAFSKNT
                     AREWGGLGIRSNVVVPGFMETAMSSTLSEEQKERIYKRTSLKAATSVRSVAETVVFLLS
                     DSACSITGQNIHVDNGTV"
     aSDomain        complement(20833..21324)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg73_39_PKS_KR.1"
                     /evalue="1.80E-07"
                     /label="ctg73_39_PKS_KR.1"
                     /locus_tag="ctg73_39"
                     /protein_end="166"
                     /protein_start="2"
                     /score="23.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="FLVTGCSRGVGLEICRALLQQGHIVYGVARSYTNEFKFLETEYAG
                     RVFFKSIDLSDSENVRKTVFREFIHNGIQLHGYVNNAAMAYDDIVTNLNLEKLQAMYAV
                     NVFTPMMITKYALRNMLLHHTKGCIIHISSISAHTGYKGLAMYASSKGTLEAFSKNTAR
                     E"
     CDS_motif       complement(21259..21321)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg73_39_0001"
                     /evalue="7.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg73_39"
                     /protein_end="24"
                     /protein_start="3"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LVTGCSRGVGLEICRALLQQG"
     CDS             complement(21327..22541)
                     /NRPS_PKS="Domain: AMP-binding (99-316). E-value: 4e-27.
                     Score: 86.6. Matches aSDomain:
                     nrpspksdomains_ctg73_40_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 66.9;
                     E-value: 2e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_40"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-20, bitscore:
                     66.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVFLCDGECEYSYDDLLRHLNQDNYFPLLKTHHLFSYFGNLVKA
                     LTNDVPLVLLDSDLSPAELDGVDESLVNQSIPLSVKRLPSMGEVIEALVHSTSEITMFT
                     SGTTGQPKKVVHSIQTLTRSVRRGEKYNNQIWAYAYNPTHMAGLQVFFQAFENLNTLIN
                     VFNRTRSEIFNLIKKHSITHISATPTFYRLLLPYERAYSSVIRLTLGGEKSDGHLYNVI
                     RQIFPSAQINNVYASTEAGSLFAAKGENFQIPASIHDMFQVVDDELLIHRSLLGQSDSF
                     RFDGDYYHSGDLIEWINREEGVFKFKSRKNELINVGGYKVNPGEVENVLNAIKGIRQSL
                     VFGKANSVLGNILCAEVQLEEGVRLSELEIRRILKDSLQDFKIPRRIRFVESFSLTRTG
                     KLKRL"
     CDS_motif       complement(21561..21623)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg73_40_0002"
                     /evalue="2.00E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg73_40"
                     /protein_end="327"
                     /protein_start="306"
                     /score="11.0"
                     /tool="antismash"
                     /translation="KSRKNELINVGGYKVNPGEVE"
     aSDomain        complement(21594..22244)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg73_40_AMP-binding.1"
                     /evalue="4.00E-27"
                     /label="ctg73_40_AMP-binding.1"
                     /locus_tag="ctg73_40"
                     /protein_end="316"
                     /protein_start="99"
                     /score="86.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ITMFTSGTTGQPKKVVHSIQTLTRSVRRGEKYNNQIWAYAYNPTH
                     MAGLQVFFQAFENLNTLINVFNRTRSEIFNLIKKHSITHISATPTFYRLLLPYERAYSS
                     VIRLTLGGEKSDGHLYNVIRQIFPSAQINNVYASTEAGSLFAAKGENFQIPASIHDMFQ
                     VVDDELLIHRSLLGQSDSFRFDGDYYHSGDLIEWINREEGVFKFKSRKNELINV"
     CDS_motif       complement(22194..22238)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg73_40_0001"
                     /evalue="4.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg73_40"
                     /protein_end="116"
                     /protein_start="101"
                     /score="16.4"
                     /tool="antismash"
                     /translation="MFTSGTTGQPKKVVH"
     CDS             complement(22550..22774)
                     /NRPS_PKS="Domain: PP-binding (4-56). E-value: 9.8e-09.
                     Score: 27.6. Matches aSDomain:
                     nrpspksdomains_ctg73_41_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_41"
                     /sec_met_domain="PP-binding (E-value: 2.5e-08, bitscore:
                     27.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKVLEIVNEIRVAKELSAITQLHAEDNLRDDLEFTSFDLAELT
                     VRIEDEFDIDIFEDGLVNTIGEVYSKLQK"
     aSDomain        complement(22607..22762)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg73_41_PP-binding.1"
                     /evalue="9.80E-09"
                     /label="ctg73_41_PP-binding.1"
                     /locus_tag="ctg73_41"
                     /protein_end="56"
                     /protein_start="4"
                     /score="27.6"
                     /tool="antismash"
                     /translation="VLEIVNEIRVAKELSAITQLHAEDNLRDDLEFTSFDLAELTVRIE
                     DEFDIDI"
     CDS             complement(22793..24001)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_42"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.8e-39,
                     bitscore: 128.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNLQQFIADHVICRPTSMFAADIEANKETLQAEIRNKSVCVIGG
                     AGSIGSSFIKAVLPFKPSKLIVIDLNENGLAELTRDLRSTYGMYVPAEYRAYTLNFADP
                     IFERIFREEKGFDIVANFSAHKHVRSEKDKYSVQALIENNDIKAKRFLDLLAVYPPRHF
                     FCVSTDKAANPVNIMGASKRIMEDMIMAYSSKFKVTTARFANVAFSNGSLPDGWIQRVM
                     KKQPLAAPNDVKRYFVSPEESGQICMLACILGKNGEIFFPKLGERQMLTFSSICDEYIK
                     AVGCEKKEFATDEEAKKFASEMAFNNKDYPVVYFKSDTTGEKAYEEFYVPGEKINMDRF
                     CSLGVIEEVVKRPMAEIDAFFTEMENIFAEPDFTKEEVVMAIKRFIPNFEHEEKGKNLD
                     QKM"
     CDS             complement(24238..24672)
                     /locus_tag="ctg73_43"
                     /transl_table=11
                     /translation="MDNETHFSIVFNIYGGSNQILPNATSATQNYYGDEAELEKDDVSK
                     DKEPALSPEATRLFSYINKVEDLRIYLVQIAECTNAVELARVIVKMGEREPKITSEEMV
                     KERFISLFFPLTPLFVSGKTVSNIRARINNAWARRPRKRL"
     CDS             24860..25360
                     /locus_tag="ctg73_44"
                     /transl_table=11
                     /translation="MIDYSVFMMGNPMDVDAAQKAYAKAQVSEIMPFSQFVKHIADHNG
                     VFTRGTVKGVIADMCECLVEMLLEGKKVQLAELGNFWISIGSEGAEDLKKFTESNITAV
                     NIVFTPGEDFQNLRSRATFNPVASRIAQAATLKAEKAGKGTVDLDAAKGKTSASTNENN
                     PSL"
     CDS             25381..25749
                     /locus_tag="ctg73_45"
                     /transl_table=11
                     /translation="MGNASDRTMPKKAYAKCVANEKVSHKKLVKKVTEHLRFFSHGMME
                     AVLEEVFNRLSEHLAQGDRVTLDGLGTFSVSLKCEGAASEALFSKKNIKGAHIVFAPCR
                     KLKETFADMEYKMAPRIF"
     CDS             25793..25891
                     /locus_tag="ctg73_46"
                     /transl_table=11
                     /translation="MKKNWKNVLLYIVRIIELLITGAAGGALGSGL"
     CDS             25888..26307
                     /locus_tag="ctg73_47"
                     /transl_table=11
                     /translation="MRTVSLIIVHCSANKAGSALRAEDIDRYHRSLGWKCCGYHYVIPT
                     DGTIEAGRPPKMIGAHCKSHNSHSIGICYIGGLDADGKTPKDTRTEAQKVALRKLIEHL
                     HQRYPKALIVGHHDLNPQKTCPCFNVTAEYIDLQP"
     CDS             complement(26373..27203)
                     /locus_tag="ctg73_48"
                     /transl_table=11
                     /translation="MVTENSMELENQAFLSNQDITGEAPKLLLCSSIASGSDLGSNEGI
                     TPMAGIGKEYPEFSWYYLYLSNKELKRYISVFSGRKAVRLRTPSGTVEERFFCFKVFSY
                     TATDHRKRFEQCAYTKEEYTVRRDSARIVKEAFATGSIQKLNTLTDEKGIEGNGWLFVC
                     APLGQLECILSAMLPRQYLVTDYNTHRAAVIPHRQMEEFIYLYESMPYNIELMNRPLED
                     YLQKKQRIRITGGVFRGKEGCIMRLHRNTRLVFAFGNMTVAVSYLHAFPFEKID"
     CDS             complement(27627..29666)
                     /locus_tag="ctg73_49"
                     /transl_table=11
                     /translation="MKKLIYTLLLLLVTFPAMAQSLFEQYERFLTEPRTYVCYRPDGKL
                     KIDGKLNESSWNKAASTAPFVDISGEGFPTPKYETTAKMLWDDEFLYVGAVLQEEDIKA
                     RLTQRDTIIYYDNDFEVFIDPDSDGHNYFEIETNARGVIFDLMLDKPYRSGGNFMVQWD
                     CPGLKTAIHCEGTLNKSKDKDKYWSVEMAIPHQALTMNFNNPLKAGNTWRINFSRVQWL
                     KEKGPEENWVWTPTGRIDMHMPDRWGYLYFVDKKVGTSQDELVYPYNQAIYKLLWAMFY
                     AQQDNYSKQHNYLRATEQFFLTDKELKDLPADARIAVEATQNTYQIAITNPAEGIRYVI
                     NNEGRFRTEKIPAREVKNWLWMRLNNRSDAEWQKWFALLKECGISGVMFEGYNENIYRL
                     CKEAGLEAHYWKWTMNRRELLDKHPDWYAVNRKGESCHDKPAYVDYYRFLCPNHQGVAE
                     YLAEDYVKEAHKPYVDGVHLDYVRMPDVILPVSLWKNYGIEQKEELPEYDYCYCDVCRE
                     LFKAKTGQDPLELKYPMENQSWINFRLDAITRVVDAITKAVKADHKAISAAVFPGPSMA
                     RHMVRQDWGEWTLDAYYPMIYNKFYYEGPEWIGRSVKESVETVNGRAKIYAGLMFGDIK
                     DNFEEVLDEAYNNGASGVSFFDGPDEEYLHKFKAYLDKRGFVVK"
     CDS             complement(29685..31034)
                     /locus_tag="ctg73_50"
                     /transl_table=11
                     /translation="MKKNRLSLAFLGLLIAASPLRAQDTPQTETAEQKDKRMEWFSQAK
                     LGIFIHWGIYSVRGVSESWSFFNNYLPYDEYMEQEKGFTASKYDPKNWVDLIKESGAKY
                     TVITTKHHDGVALWDTKVGDISVVKSTPAKRDLIAPFVKEVRKQGLKLGFYYSLLDWSH
                     PDYPNKTRTEVRYKNDPERWARFNKFNFGQLAELNKTWKPDLYWFDGDWEQSSEAWNSK
                     GIVDLLRSDNKNVIINSRIQGYGDYATPEQGVPVVRPEDKYWELCMTMNDSWGYQHTDS
                     NYKSPYILLRTFVDCLSMGGNLLLDIGPKEDGSIPEEQIAVLKEFGRWTKKHKEAIYET
                     RAGIPTEHFQGYTTLNKAGDILYLYLPYKPNGPVEVKGLMNKVNRIWVVGNGAMLNYKV
                     YNKNYWNSVPGNLYIDVPQQVQDEQITVLAVLLDGPIKLYRGVGQVQDNN"
     CDS             31159..32016
                     /locus_tag="ctg73_51"
                     /transl_table=11
                     /translation="MSAKKKKQSNSSLRVIIILVLLGLLAYKHQLFDGKLLENIPTIES
                     NEEKPEILTSPQHGGALEIPTMQSGTGGQILKRKGYTLSYNADYKTPQWVAWELTKKET
                     KGKEGRTDKFLPDPDVRGAKAYTGDYTKSGYDRGHMAPAADMKWSKQAMKESFYMSNIC
                     PQNPNLNRGDWNDLEEKSRQWAKKYGAVYIACGPIYDTKRPKRIGNNKVAVPHAFYKVI
                     LINDKKNPQAIGFIFPNSAGHKPLKKYIVTVDSVEKRTNIDFFPALPDEVENRIEAERV
                     QELP"
ORIGIN
        1 gtaatggaag agtgatgagt tgttcgtaaa tctcgtccgt atgcttaaga gtcgtattat
       61 tttgattacc tgtaaacaat gtaagcaaat ggttggggcg ataatgtatg cctgttgcca
      121 ccccattgtc attcaaacat tgtttcacaa tatccctctt gccacaagtt attctaataa
      181 caaagatatg aggaaccact tcattataat tacagggtat aatttttatt ccctttacat
      241 tatcaagttc ttgctgataa atttttgcca gcctttgacg tatttcttta aacttaggaa
      301 atttcttcag ctgagtataa cctattgcgg ccatgatatt actcatatga taacgccacc
      361 ccggttgatt gacatcaaac acccatgttc ttgtaccctt gaatctacta tcggtatcat
      421 tctgtacact caaaaggcga gcatccttaa ttattttctg tacatcaagg tcctcagtaa
      481 ttatcatccc tccttcacca gatgttatat tcttgatacc atccatactt atacacacca
      541 catcaccaaa agatcctatt aaccgacctt tataataagt gccaaatgca tgtgatgcat
      601 cttctattac tcgtagatta tgcttttttg caaattcata tatagcatca agattaccac
      661 attgtccagc ataatgtaca ggcattatag ccttcgtttt tggagtcagt ttacgttcgg
      721 catcatccaa atcgatagta agcgtatcat catccacatc gcacgccaca ggtatcccac
      781 ctgtagctct tatagcttga aaacaagcca catatgtaag agactgtaca agtacttcat
      841 ctccatcttt tattcctaca ccttgtactg caagatgcaa agctgccgta ccagtattta
      901 caagtgtcac gtcacgccca aagaaatctt ttaaatcatc ttcaaattta tgtacatcct
      961 gtcccatacc caaatactct ctatgaagaa cgtctgttac ggcatctatt tcttccttac
     1021 caatgcaaga tttggacaat ctaatatttc tcataaacat catcatttta ttatcggtat
     1081 ttctctttcc cattttttcc atggagcaac tccatcaata agcaactgtt ccaatagatt
     1141 tttttcacgt atattatcca tacattgcca gaacccctta tgtgtataag acattagttc
     1201 accttcggta gccaacttat tcaatggttc tttttcaaat atggtttgat ctccttctat
     1261 ataatcgaac actctaggtt ccaacaccat atatccggca ttaataggta caccatcatt
     1321 gatattcttc tcacgaaatg aacgaatgga attattttca tcaatattta aaaccccctt
     1381 gtcttgtgct tgaataacag cagtaagagt tgctatttta ccatgctttt tatgaaatgc
     1441 cacaagctta ttgatgtcaa catcacacac accatcacca tatgtcatca taaaggtttc
     1501 attgttaaca tattccttta tacgtttgat acggcctccg gtcaatgtgt tatatcctgt
     1561 atcaactatc gttactttcc aaggttcaag atttgaatga tgtacagtta tttcattctt
     1621 accgttacgg aagttgaagc taacatcgga attgtaaaga aaatagtttg caaaccattc
     1681 cttaatatat tcctgtttgt atccagcaca aattatgaat tcattatatc cataatatgc
     1741 atattccttc attatatgcc aaagaatggg cataccgcaa atttcaatca tgggctttgg
     1801 cttaaattgg ctctcttcac taatacgcga gccaaaaccg cctgctaaaa gaactacctt
     1861 catatagatc tgctaatttt gttgaaatca aactttatat cactctcttc tattggaatg
     1921 tttacctgct ctagaggatc atgaggaata ttggctacat ttagaagaat gcttttacct
     1981 tcacctattc caacgaagcc catccatact ccagccggta ttgtgatcct tcgatacaat
     2041 tcaggtaatt caggtgacaa tatcacttcc atgtactttc caaatgtaga agagttctca
     2101 cgcccatcat ataaaacgaa atgtatcttt cctacaatac atactaggtt taatgtcatt
     2161 ctagaatgac gtttccatgc ctttaccaaa ccttgtaaaa cacttgagaa ataaacttca
     2221 ccaaatcctt caaatccagg gtcaacacat ttcattgcat gaaatacatc ccctttggga
     2281 tgagttatct gttttaaggg agtcagcaaa actccgtcaa ttgtgatatt gtccattatt
     2341 tccaattatt ttgcccaatc aagattctgt ttttttgcag cttccatata tgcattgatt
     2401 tgtttttctg tcaaagcaaa catatcctta gcctgctcta catagaatgc acgataccat
     2461 tcagcaataa aattcacaca ttcgtcataa tgcaaggttg aatgccaatg taaataagcc
     2521 aaggccttat cacagttcag cttaagcaat gtagcttcct caaaaggtac attgcctgtg
     2581 agttttgcag ctttgttctt atccaatccc cataaagtag caagatcttg aaacagttca
     2641 aatacggttt ttgtctgttc tgcacgtgga ccaaagttgt aagattcccc attttcgcat
     2701 ttgccttcac ataaatattg cgccaacgtc agatatccac ttaatggctc aagaacatgt
     2761 tgccaaggac gagtcgcctt tggacttctg atttctacag tctttccttc tgaaaaagct
     2821 ttcacacaat ctacaataat tctatctttt gcccaatcac cgccaccgat aacgttacca
     2881 gctctagcca caccaaactt aatgtttggc attttcttga taaatgaatg ccaataactc
     2941 ttaatgacaa gttcggcagc acctttagat ccagaatata tatccttacc tccaatacca
     3001 tctgtttcac gataccccca aatccactct acattatcat acgctttatc agaagtaatt
     3061 agaacacaag tacaattcca atcaatgttc atgacagctt cacatacaac agctgtaccc
     3121 acaatgttag tagtcattgt ttcaaatggt tcgcgataac ttgtcaagac caaagcttgt
     3181 gcggcaagat gaatcaaaaa atcaggtttc acttcctgca caaaatcatt aaattccctt
     3241 ttgtttctaa tatcaccata gtgttgacat atcttatctt caagatgaag tgtatcaaac
     3301 atcgatggag ttgtcggcac accaatcgaa tatccataaa cctcagctcc catcatttta
     3361 agccatgtag acagccaagt ccctttaaac ccagtattac cagtaataat aaccttctta
     3421 ttcttataaa tattactaaa tgccataact atatgttttt tttatattcc gcaaaaagat
     3481 attttgttgt tttgaatcta taataaccgg tagattcata atcgattttc ctattttttc
     3541 cgcaactggg catcctcccc aatgatatcc aaagtcacat atattttctt ttgttgcaac
     3601 aatcggagtt ttaaaccaaa tccaatcatc aatgtatgag aatacagtaa gagcgaaata
     3661 agttgaataa gcaatacgca aaggaataat gtcacaacca gtatcataat aagctgcagg
     3721 catatcttct tttttttcta caacctgtaa aatttcttta agccaactct gcctttgatg
     3781 aatattagct ttatattgtt caagaacatg taatccaatc tttgccaaaa cagaaggtag
     3841 tttagcagga taactgtaat aagggtttat tgcgattttg gcagatgttt ccaactccaa
     3901 ataaggagat atttcattat gaatatgtag cttattcatc aaagcctttt tatagttccg
     3961 cattatgtat attttatgat ttacagtttc tatgcggtgt tcatcaatat aagtctttaa
     4021 gatcattcgc tgatgttcgt tgcttaaatc cccacaatca tcacgcattg cccgaataga
     4081 tgtagctatg tctatatcat tagtataaac aaagcctcct ataagtgtat taagaggttt
     4141 ggtatgatct gttgaaaata ttgcagcatc accataattg ccaactataa tacttttata
     4201 ttttgaacca aaggtcaacg cacaatcttc cactaaatag caactatgag atttagcaat
     4261 ctcctttatt ttatcaatct tacatggaat tccaaaagaa tgctgagcca caactacttt
     4321 tgtccgattc gtaattttgg acactaaaga ttctgcagac attcctaagg tatccttgtc
     4381 gatatccaca taaattggag ttgctccagt tcgcaaaaca gcattagcca taacagcaca
     4441 agtaaatcct gtaagagcaa cttcatcgcc ttctcttatt ccccagcttt ttaataaaga
     4501 atagaatgac atacgtcctg atgcgaaagt cacgacatgc cctcctccaa gaaattggct
     4561 tagttctttt tcatagcgat taacataatc aagattagga gcctctatca gtgcttcata
     4621 gtctgactgt ttttctgata tatcaatact tggagaaata aagctactga tttcagacgt
     4681 aaacaatagt ctaaacattt ttttcatttt tgatattatc ataatctcta aatggtttcg
     4741 ttttccataa ttcctttcta ttcaacgtct aataattgac ttcaccaatg aatacatttc
     4801 tctattacaa cacactgata ctagaattga tattaaaaca atcaatccca taaccaataa
     4861 attataacaa agggaaatct tattatattc ataagccata taaggcttta caagagtact
     4921 taatactaat agtacaatta aaggtaaaaa caaagttttc aaaattagga atagtgaaac
     4981 tatctgacca gcattctttg caaaatctct gtataatgaa taccaataaa gaatacccaa
     5041 aaatatagga atcagtcctt tagatatagc gaacgaaaat acgccccatt tatcaatagt
     5101 aaaaaaaatc aacaaccagt atagtatagg ttgaaatata ttaaacctat taagtaaagt
     5161 agttttttca attgcaataa aataagaaga actagggttt gagagaaagc aaggaaagaa
     5221 acaaaacacc aaaagtgata aaatagaact ggattcctca taattgaatc caacccaact
     5281 tataataaat ggttcactca gcatagacaa tccaacaatg ggcagaacta ccattggcga
     5341 gagcattaat aacatccgat tcacaaattt catcagtccc accctgtcat tttcaccaat
     5401 caaatgatta tatcgcgatg aataaggtga ataaagtaat gacacaaagg ttcgtacaaa
     5461 ggtcaatgca gaaaaagcta tgccataaac tgctactgcc tccagaccaa caaaatttga
     5521 aatcgcgatt tgatcaaatt catagaacaa cacccaagaa agtatagata taaatgaagc
     5581 tcccgtcaag cccttttctt tatcaaatat aatacggtca aaacggatag ctttaagaaa
     5641 ttccacaaat gaatattgat actttcggac ctgaaaagct gccatcaata ctacggatag
     5701 gttgataaac tgcacgaatg caaaataagg taccaacaaa taattttcac ttccaaaaaa
     5761 aaagaaaact gataaaatct tcagaatact gcctaccgca gagatacgct gtaatttata
     5821 atcttccaca cgtatggaat aaatcatatt aagaattcgt tggccaatga ttaccggaca
     5881 ggaaacagac aacagaatca gcaaataacg tgccgtataa aaattttcac gatccggttc
     5941 caattcaggc atgagaattt gagggaatat gctgattatt ccaaatagca aagctatcag
     6001 cataaacatg ctaagcataa taaatgcagt aaaacctatc gtacgaattt cattctttcg
     6061 gtcaccacga atataatatt ccgctgcata tttcaatccc gatgaaataa aacctaaatc
     6121 agcatacgaa aagaatatag tcagagacgt acaaacactg taaataccaa agagtgtttt
     6181 atttccagaa agtaaaggca tcacaataaa aagcgaaaga aaacctaaaa ttatggataa
     6241 tccttgccaa atgtaaatcc taaaatattt tccgcgatat gatatactca taggtatcaa
     6301 gtgaaaagtt ggaaaattaa ctgaggctct agtttggtaa agaaatagtt tctcaaccga
     6361 tagccctcgg tcattgcatc ctcaatattt agattcaata tcctaacaat agcatccgaa
     6421 agttcagcca aattattggc agtataccac aatacttcat tcacctcttc tattttatca
     6481 aaaagaatga tggaaagcgg atctttcaga ttaataacag ggattcccaa acttaaggct
     6541 tcaaacatca cagatgtgtt agctgcaaga attgcgtctg ctttcagcaa gaaagagttt
     6601 acattacctt ttactacttc tagctttccc cctgccttgt ttgtacagga aaccatccat
     6661 gatgaatttg catcaggatg gggcttcaaa agtatattaa tattagcatt agaagattta
     6721 ataaaatcag tgagcaattc gtatttatac tccatatcat aattatcgag tgcaaatggc
     6781 accaagagcg tgaacttatc atgaggtttg gtgcttctat gactgctata tatctcttga
     6841 tttctcagtg caggagctat atgcttatac ccgttataat tttgatagaa ctttagcaga
     6901 taactgctac ataaataaat atcttttgga gcaatatgac aaaataattc tttattcgat
     6961 gctataatat gtggaaaaat tgttgaatca gcaataaatc ccatatatcc atgaactttt
     7021 gcctctggat agtattgatg cattgcgtaa tatactgatt tgtcgtagct ttggttctca
     7081 aaccaatcca caaataagca aatgtcaaca tccaattctt tcattctcat aatagctctt
     7141 tccatcaaaa tggcatagta gaaataactc tgattactct ctttgtatgc ctttcccaaa
     7201 agccattgaa gactgaatcc ctgataagta taacttgcaa aatctggctt ttcaaaacgc
     7261 cccatatagc gccatgcgta gagataatct ttaaaaagta aaaaatcact cataaagaac
     7321 aagttttcct tagaattggc aacaataata tccaattgct tttttgaggc aaagggcaaa
     7381 tacaaaggca tgaaatatat ttgttctttt tgggcatcaa tcaatttatc tacagaattt
     7441 ccataaaaac gatcccaata ggcatcaacc ttttttgcaa taaaggtatc aatgatagtt
     7501 aatcttcccc ctcggcacac cttattacgc ctctctttcg aaccgctaag ccatgaacag
     7561 agtgaccata ttccatatcg aatattattt ttccataaac gaatattatt tttcaaagaa
     7621 cttgtcttac catgcacatt tatcttagga tacagatttg aaatggtttt tcgcaactca
     7681 tcattatcca ctatgatttc ttctattatt tctccgctac ttataagctc tgatatcaat
     7741 cgcaaggact caagttctgc cagcattgaa gaaaaaacgg tactacgaga atttacgtta
     7801 caaaccagcc attccaaact atcacgatta taatcaatta actgttcggt caatgcatta
     7861 tagtcggcaa tcacattttt tttcagcttt gcctttaatt tactctgttc cagagttagt
     7921 tcatttagat ttaatatcat ctattttatc tttaataaag cttcactcaa taaatctgca
     7981 cttgcttttc caatctcatc ttttgtataa agatatttat caataaattc atcgtacacg
     8041 ctatcaaaca ccacagggac ggatatatca gcatcttctg catcaatatt taccaatgga
     8101 ctttggaaaa aaccagagta actcaactca gctgcaatgc catacttgtt aacgacttca
     8161 tcagtcgtga taaacttgat tggtttgtgc tgtattataa gaaaagtaat agctgtactc
     8221 aaatgattaa tagcccatgc acaaccctta cacaactccg cagtctttcc aaataatacg
     8281 ggtctgccgt caaaatagtt atgttcatga tatttttgag cactaggatg tgcagctata
     8341 actacaggta acccatactt atcctccaca cgtttcaggt aattatttac tgatttaaaa
     8401 tattgttcag gatcaatatg tccactggca gttacttcaa aatcaggatg gaaaggcata
     8461 taagcatcaa taaacacaat atatttccta tcattatacc tttccatttt atccacctta
     8521 ttaaaatgct ctatatcata gtctacaatt gttattttct gcgtcttgtc ggaaataagt
     8581 tgagatgcag agttaatact gtgtacacct tgagtcacag cataatcaaa atcttttaaa
     8641 taaccaattt ttctcaatag aggaatagac ctatgaatga aataatacct cactctaatc
     8701 gggttaaaca aaagtttaag tctatgctcc attctatttt tggggagagg caaatgcata
     8761 cttccaatat tgaaatagcc aacatttttt tgttttgctt tgcttaaaat tctaaacaac
     8821 ttcaaacaag gagcaaatac aggcattaat gaaatgagaa tagcatcttt attgcgatct
     8881 agatttataa tccgctgaat ttctttccaa gatttgggta tagtttcaca acctttggaa
     8941 gatacattac ttaataaacc aactaacggt ccaatccaaa catactcaat tgggaatccc
     9001 ttttcttgca attgttttaa cagaaaccta tcattataga cttctttcca aggttcaata
     9061 ttaaaaaaaa acagttttgg cagattttga tttgacatcc ttatttttta ttataattat
     9121 ctctaatatt taaagtatta accacttttt ctgtttcaaa aaataccata tttgtcctaa
     9181 atatcaaaat tctctttcac aatcattggc tttatattat acccataaat atccatagtt
     9241 gctacccttc aaactcaaaa tatagagaat tctttaaact cattttcacc agtcaagtat
     9301 acttccccat aatccttatc cagcctttat gttaaagcgg tatttaacac cggggtataa
     9361 aaactcccca ccatattttt ccccttccag ttccacatcc aatccttgtt ccagtgccag
     9421 attcataccc ggaagaatat cccaagaata acatcctttc agatgtaaaa actgtctgta
     9481 acagcctcgt ataacattat acatattata catgcaacac cccataatac gatattcaga
     9541 gccctgttcc aacctcttaa aatcttcagg ttgcatataa gatgacagcc cacaaattct
     9601 tgaaccaata attttagaaa actgatcacc tgtacataaa cgaattccca attcgggtaa
     9661 cataatcata ctttgataat gcctcattcc tttataaaca gaaatgccga ctccccattc
     9721 cttcagacct gaaacaaaat tctccgtacc gtctatcggg tctaccgtta tcacatactc
     9781 aacttcttcc aaacgtgaca aattcgtttc tgtttcctct gaaataacca aataatcctt
     9841 cagattggag tccaagaaat caaaaatgag tttttcacac aatttgtccc ctttggaaac
     9901 aaaggtatga tcggatttca actctgaagt attccgtaag gagagaattt caggcaaatg
     9961 aagcataatc agttcatgta tgcttctaca aatatccggt tcattcatat agagacggag
    10021 ttaaaaattc aatatccata acctttccta tttcactgat gcgatgcttt atcgctttat
    10081 tcatttccaa gacataatcc ctatcctgaa tcagattcaa acgctcctga tagtagtttc
    10141 cctttttcat agagtaaccg tccatacctg ccagataaac ttttcgagga gacagtttct
    10201 gtaaaaggtt caaagccatc agagccgaat tatcacgaat aatgtccact tcgttcagca
    10261 aagaaacata attgacacaa tagccagatt gttcttgatt tgcacgaata ttggacgtat
    10321 aaatcaaact cacctccttt ttcatcggat taaaagtcgt agcataccgc ttggcattag
    10381 ccaagaaagt aaagtcacaa tccataaaat caggaacaaa ggtcacagaa ataagcagac
    10441 agttctccga attctgtttc tggacaattt cgtcataaca gtctgtaatt gaacctcctg
    10501 gagccatcag tataatattt cttccaccta ttttttcttt caagttcttt aagacataag
    10561 tatcatccac ctcatgagat tgatactcca aataaatcct atttaccaat tccttattgt
    10621 ataaagaacg cttttcgaca ggaatcatat gcaatatggc agaaatttcc ttcacagcaa
    10681 gcgtctgttt ctgagccaga taagaggcat aattaggatg gcaaccatta atagccgcca
    10741 aataataagg aacagtatac ccccactcat gtttctgcct aatatgaatg atgaattcat
    10801 caacaacctc caacaatggc tctatagcat acatatgccc ttcacggtca ttaacataat
    10861 tggcaatcag ttccgtattc aggtttccgg cccctcgtcc cattccatag atagaagcat
    10921 ccaacgaaat gacacggtcg cctacatatt caaaaaactc ctgagagttg gaaaaggaaa
    10981 gctgtaagtt attgtgggaa tgaaaaccca tatttattga cttgtccaga ttagtattga
    11041 tcagataaaa aaatctggct atatcattct tgtgcatcag tcccaaagtg tctaccagat
    11101 aaaaggaata gggttgcaac tcattcacct tctctatcag atggagaagc tggatatcag
    11161 tataactgga cgtgcctacc ggttgcacaa aaaccttata gcctttttct tttatttccc
    11221 gacagtattc caaagcaccc tccacttcat cataatgaaa agtgacccgt attccatcta
    11281 tggaatttct agtacaagga ctcagctgac tcagatcgta ttcaccataa cagaccatcg
    11341 ctacaaacat ggtacgtcca tgttcattag gtaacaggga ggctatctgc tctgcggcat
    11401 taaaaatgga ggtatcctcg tcgtattcac catcctccaa aaatccacat tccactatat
    11461 ccaaacctgc atgggtcagt tgttgaagaa ttttccgtat ggcatattta ccgaatcgga
    11521 aattattgat gtaccctcca tcacgcaaag tacaatctaa tagttggatt ttgctcataa
    11581 tacgatctcc ttatttttaa tcctgcgctc taagacttct gtcacaattt tcacatcagc
    11641 ctgcgtatct acagataaag tttcagctgg aatctctaca aactttattt tttttccgtt
    11701 ttccaaaaaa cgatattcgt caatatcctc tatactttca atttttccgc gtttattatc
    11761 cttgcagaaa agcaaggcag aacgtgagaa acattgtatt ccaacaaatt tcatatagtc
    11821 aaaatccgag ctggcctttg gatatggaat aggagtccta gccatataca ttgcatatcc
    11881 taaattatcc gttaccacct ttatacgaga aatgtccgcc acctccactg tcttttttat
    11941 tttagtcata gcattagcaa aataaaaatc agcaggattc aagtcggaag taggtaaaag
    12001 tcgttctaca tattcgggca tcatcaaagg ttcatcacca ttaatattaa tataaaaatc
    12061 agactctata ttttcggcga attcagccaa gcgatcaaga tgcgtgggat gactatctga
    12121 agtcatcaca tatttaattc cataatccga acagaccttt ccaatacgtt catcatccgt
    12181 tgccacataa atttcactca atccttttac ttgacaaagc tgatgatgaa cccaccaaat
    12241 cataggttta ccacaaaggt ttactaacgg tttaccttca aaacgcgtag acttatagcg
    12301 cgcaggaatt actgctatta ctttcattgt atgttgtatt ttaaatttat ttcaaatgtt
    12361 tcaccatctc tctagccctc gccaattcat catgctggcc aatatccagc caatatccac
    12421 taataggata gcgaatcacc ttgtatccct gttcaatgag tttatccatg aagtcagtgg
    12481 cattaaagaa gatatcatca ggaataaggt caaacagttt gcgtttgata aggtatatac
    12541 cggcgtttgc ataataactg atggtgggtt tctcggtaac gcccttgatt tctcgtcctt
    12601 cgagattgaa cacaccgtat ggcaccttca ctacgtaggg cacagctgcc acactcatgt
    12661 cagcatcatg ctgacagaaa tgaaggaaaa agtcctcaaa atcaatattc gtaaaaaggt
    12721 ctgagttcat taccagcacc gtatcattgt aaaaagtttc cacgaacttg atactgccaa
    12781 tggtacctag atatttcggt tcacgcacag taactatctt caccccatcg cgttcctccc
    12841 ggaaatgttc ctcaatctgg ttgccaagat agttaaccgt tacagatata tgattcaaac
    12901 cgtatgaaag caaacgatca atattataat caatgataca cttgtcacct accttaatta
    12961 ggggcttagg agttttctcc gttaacgggc gaaggcgctc ccccttacca cctgccatca
    13021 gtacagcatc aataggtagt ttggttatat aatgttccaa attgatgatt tcgcaaatat
    13081 gattctcttc atcaagtacg ggtactaaac gcatctttaa atcacgttgg cggtgaatat
    13141 cctccacacc atcgttcact ccgcgacgta aaaagttaaa attacgatgc atggcctcac
    13201 taataggagc atccacatct atacctttaa tcaaggcacg acgcacatca ccatcggtaa
    13261 gggtaccttg catccttttt tcagcatcta ccacaaaaag cactaacggt tcaccatgaa
    13321 tctcgttgat gcaacggatg gaatcaatga tggaaaggga ttgggagatg atatgggaat
    13381 gattcatctt atttcaatta tattagatgg ttatttatca tgtattcagc tatctgccaa
    13441 tctatcattg tatcaagatc aatagaatgc cctcgatcca tcacatactt gacacgttta
    13501 gtgaatttat aaagtggcat ccgcttcaag ctatcgggat taatgatata aattgcacca
    13561 ttgtattcgt aaaccggtgg acaatcttga cgacgggtat aatgtccatc cccttttgaa
    13621 atgtgcaaca ttccattggc atcgtcctcg aaacaaatat aatatggatt agaatccgtt
    13681 tctttcacac tgactaccat atcaatctct ttggaataca acttaagtgc ttcctttatg
    13741 tgattacccg tccgaaaagg agatgtggcc tgaagcagca caaccacatc aaaagtttct
    13801 ccttttgatt cataataatt caaagcatga agaagaactt cgtatgttcc cgcagtatcc
    13861 gtagcaagtt cttccggtcg tttaaatggc actttcaatc catattgttc aactacttga
    13921 attattctgt catcatcagt ggatacacaa atatgatcat tatcggtgac tgctcttgca
    13981 gcatcaatag tatatccaat caaaggcttg ccaccaagta tcttaatatt cttaccagga
    14041 atgcctttac ttccccctcg gacaggaatg ataaccaata tattcatact tctatagatt
    14101 ataaaatgat ttccgtttca gttcatcaag cggatatgta gaaattacat cgaaaacaga
    14161 ttgtaccgta ttctcttttt cgtagggatt ggaagctttc aatgcgactt ccttaaatga
    14221 taaagaaagc accatggtaa gcccccttat aatagattct ttatcacttg cacaatcgag
    14281 caccgaattt ccgtgaacgc gtcctttttg acgatcccca atattgagtg tcggaatatg
    14341 aacggaaggt acttcaagca acccactgga ggaattgcct actacagccg ttacatactg
    14401 taaagctgaa agataacgtt tcagacctaa cgaactgtaa caactgcaac ggtcactatt
    14461 ccgactgcaa tagccctcaa tagcctggcg tatcacttca ctgccctcat ctgaattagg
    14521 catggtgaaa agcaccttca gtccggggaa agtatccaac gcaaacagaa aatcatcgat
    14581 ctcatccttc ggactacgat tgcccaaagt gaccggatga taggttacta aaatgatttt
    14641 tctatcgaaa gtgaagttta atgaatcttc caagtcttgt ctgctcatca aaggtatttg
    14701 cttcaagttt tccactccaa tggctccaac atagaatact ctatccggct gttcacctaa
    14761 ttggattaca cgacgacgat aatcttcagt ggatgtaaaa tgaagagaac tcatttttgt
    14821 aatggcatgg cgaatgctat cgtctacggc tccttcactg atttccccgc catgaagatg
    14881 tgctatggga atccgttgca acatggcaac ggtagccgtc accaacattt catatctgtc
    14941 tcccaagatt accaccatat cgggatggag ccggagaagt gcttcattca tacctttcat
    15001 ctcttctgcc atggaatcaa tcaccccata agagtcatcg gacagctttc tcatgggcac
    15061 tttagcatca atatgaaaac cgtcacattc tatctcctga taggtatttc catattcagg
    15121 aagcaaatgc atattggtag caatgacttg aagctgacaa tctgctgatt catcgattag
    15181 acgcatcaac ctgctgagta atccgtactc ggcacgagtg ccggtaacta cacaaatttt
    15241 tctcatatct ctatcaattc atcttcattg aagtcacgaa cagctctctt gcctattatt
    15301 tcgggccacc gcataggatt tataccgttg cctggacgtt tcaccgtaag gttctcttcg
    15361 gtgaacaact cacctttctt aatgtcccga gcagccacga tactcttgcg tgcaacggct
    15421 ttgttcttac gttcggaagc ggagacggtt ttgtatccca tgccgatagc ttgttcaata
    15481 ttacgaatgg cagttaccat ggcttttaat tcatcaggtt ctaatgatgc tttatggtcc
    15541 ggaccgggaa gggaacggtc gagcgtaaaa tgcttctcta taatctcagc tcccatagcg
    15601 acagcggcaa tgggcacttc aataccttgt gtatggtcag aatagcctac cgatacgccg
    15661 aactgagaac gcatctcatt catggcggag agattgacat catacatcgg ggtgggatac
    15721 tcagtgttgc aatggagcaa agttatctgc tctttctgca agccatgggc tgtcaataca
    15781 tcaaaagcag attgaatctc ctccatctcg cacatacctg ttgacatgat gacaggaaag
    15841 ccagtctgag ctatttttac cagataagga taattggtaa cttcgcctga agggattttc
    15901 caaaagccca aattcaagga tgccagatag tcaatactct caaaatcgaa agcagtggag
    15961 agaaatttca cgcctttctc acggcaataa gttaaaagtt ccacatgctg ttcgtgcgaa
    16021 agctcaagct ttttgagcat attgtattga gaggtattgc catcaccaat attatgttgc
    16081 tgatactcgg cttgttttgc ggattttgta accagattct cagccttgaa actctgaaac
    16141 tttacatagt caacacctgc ctcagctgca acttttataa gctttttggc tatggtcaga
    16201 gaaccgttgt gattaactcc ggcttcagca ataataagcg tatgtttcat tattgattcg
    16261 tttgtagtct gtctcccact ttcaacttac attccgattc gtattgcaca attttaatgt
    16321 aggaatcttt tgtttttaca atagggcaag catgctccaa tccgatgact tgtcccggaa
    16381 tacctttata ttgcggataa ttttcattat attccacctg attgataagt acaggaatgc
    16441 ccttgcagaa agtggttgcc atcggaccag gctggcagat agagcgaaca aagttaaaca
    16501 attcccgtga agtcatctgc caatcaatca actcatcccc tatttgccgc attccacaat
    16561 aaagtccatg atgagaaatc atgtcttgcg gcacgcgctt ggctttacct gcttgaatgt
    16621 ctttaatggc ttgataaaga atcttgggac acgcttcgta agcgacttga agcaaggtat
    16681 tgtaactgtc tgcatctgta atgggaaagg ttcgttgcag gatgatgtcg cctgtatcta
    16741 tgccttcgtc tacatagtgt acagtgatac cgaattcttt ttcatcattg ataagtaccc
    16801 aattcaagat gttacgacca cggtagaaag gcaattttcc ggcatggcag ttgatcgttt
    16861 tacatggagg caaatcgaat attttgcgtt tgaagatttg gttgtaactc atagatacaa
    16921 acaaatcgca accataattt atagccttct gataaaactc ttctgagttt accttaaccg
    16981 gcatcaagta atcaatgcca tattctaagg ctttattctt cagatactca tctttggtat
    17041 cattacgagg aacaataaaa acaatttcta aagtttcatc cttcagtaaa gtgtctaaag
    17101 taaaatgtcc ccaaagacca tcggcaaaat aaccaattct aaatttcttc atttttgtat
    17161 agtaattaat taagctgctt tctcgcagga aagagtattc atactgctac aatacatact
    17221 atcattgtct gtaccgataa tggtataacc caaaacttct tcaccaacct gtgaaggaat
    17281 atctaaaatt ctctttataa ggtatcctgc actttcggca gcctctatca ctgacttaca
    17341 atgaccgcca ccaccgacta aaatcaaagg tcgtttcatt attctgttac aatcttacag
    17401 aactgggaat attcaccacc cggtcagcca gccactcagt gttctcaagc ccgtccgtct
    17461 cgcaatgctc gaacatgggc agacggttca tcaattccca aactggacga gtcatcacac
    17521 cgtgatcatt tgtatattcc aaaaattcaa gttgagcaac cttatccttt agtaccaccg
    17581 cattgagcca ataattcgat ttgcaatcag caggttcagt aaagaaagta atatcttcct
    17641 tacccttgaa aaactcaaca taacgagcgg ctgtctcacg cttatctgcc acatagcggt
    17701 ctagattctc caactgggca caacctagag cggcattgat attcggcatc cggtaattat
    17761 aaccaatatg gtcatgacga aactcccaac gatgaggtat cttagcctgg gtagtaaggt
    17821 gcttggcgta tgcgcccagt tcttcatcct ggaaaagcaa catgcctcca ccacctgtag
    17881 tgatggtttt gtttccatta aagctaatag cacccacctt tccgaatgta ccggtatggc
    17941 ggcctttata aaaactgccg atactttcgg ctgcgtcttc aaccaattcg atatgccact
    18001 cacggcagat atccgccagt tcatctattt ttacgggatg gccgaaagtg tgcatgggaa
    18061 tacaagcttt tacacggcga ccggtacgct tgttatagca aactccttct ttcagttcag
    18121 cattcctctc cagccatgcc ttgacagctc ggggcgaaag tcccatcgtt tctttgtcca
    18181 catcaataaa aacaggatat gctccgatat aactgacagc attgcaagta gcgatgaagg
    18241 tcagagcttg ggtgagcacc tcatcatcgc gttctacacc cactagcagc atggccatgt
    18301 gaagggcatt ggtaccactc acacagacta cggcacgctt ggcaccggtg tacacagcca
    18361 tatcgtgctc aaagcggtca acaaaagcac cgacacttga cacgaaagtc gtatcaatac
    18421 attcgttgag gtattttttc tcgtttccga taaacttggg agcactcagg ggaacaaaat
    18481 cttgtgttcc aaaaagatgg tgaatgaatt cacagatttc agcgttgttc attgctgtat
    18541 gttgaattat tatttaatac cactgattga caggcgcatt ggcatcttta ggcaaatcat
    18601 tagtgtccaa ccggggaaga ttaaatatag catcgccttc atggtcagta aggtctgcca
    18661 aatccacatc ggtagtcatg cccaatttgc atccgttttc cttcagcagc tgaatggttt
    18721 ctttattacg gtcaccgtat ggataacaga tagtccaatt gtcgacatcc ccacccactt
    18781 catttataaa ttcgatggac ttcttaattt caaattcctg tttctcacgt ggcaatgagc
    18841 ctagccaata atggtcataa ccatggctgc caatgtgcat gccacaatca accatacact
    18901 tgatttggtc aaccgacata taaagttccc tgctaaaggc agattcctca atacctacaa
    18961 ttttctcaaa cagaatatca gccatcctct ttcttaatgc ttcaggcaaa gccacttgaa
    19021 gcagccgttt tacgaagata acctcggcag gatcgaaacg gttagccact gccagttcct
    19081 tgaaatattc atcgtatgat tttaacccga actcatccgt attggccaga atgagctgtt
    19141 ttatctcatt caataaaacg ggaaaattat cttcgggtgt agaggcaaga ataaaatgta
    19201 tcttatttac atccagtacc gtatgctctg taactgcctt cactggagga tagaaggcac
    19261 cttgaatatg ctcatgctcc aaaatcggga aaacatattc aaaatggtcg gcataagcat
    19321 catcgaaaga gagaagcacg gcatgaggtg gcaatttgtc actatgcccc ccccctatat
    19381 gcatttataa cctgttcaat agtgacaaaa ttatagtgtt tctgcagaaa tttgatctgt
    19441 tccttaaaaa gtcgcacatc gcatcctttt atttggggat agcgtgaatt ttgcaaatcg
    19501 cgcacatagt ggtacatgac cacggtaagt ttatcagcat tcataatagt atgaattaaa
    19561 attagagtat gttggggcgg tcctgatcgg aatccgcttt aaatgcgaca taattatcac
    19621 cctttgtctt atatgctatt tcaatcttca cattacgctg ttcaaaaggt tcaaaatagt
    19681 tggggacgat tgtctcacca tccaaatcca acagctcaaa tcccattttt gtaaaggtct
    19741 cttcaggcag cccaaaattc ataaaatcca tatattccgc tcccgtctga taaagtatat
    19801 cgagtagctg tcccttgaca catgtattgg gaagtttacc caatacatca acaattctaa
    19861 aggctgatga atcgcccact ctcataatcc gcactgtcca aacggattcc aatattccat
    19921 tcttctttac ctcgacaaac tgataatggt aaacaggatg ttccgcaaag cgatggcaaa
    19981 aatacaaagg ggtcttgaag ggagcgtatt ctccttttat agctatttta tcccattcta
    20041 cattatggac caattgcagg gtatacgatt catcggaaat ggcagaacca ttctggcttc
    20101 ctacaggaaa gaaggctatt tgataattct ttatgcggct gttgcgaagg taatattgac
    20161 gaaggtagtc aaccggtatg cgggagactt tataaatctg cctggcaatg tcacttatac
    20221 ctatagccgc ataggagtga aaatatggta atttgaagag gctgcgccac aaaaagaaag
    20281 ctaccgtgtt taactccgag ttataaatat catctcgtat tttccatatc gctccccaat
    20341 aatcgccatt tccaaccaaa tccttatcat attgcgcaac cggaatgaaa cctatcaaag
    20401 catcatattc accggtctct ttattttccg caacaaggaa attgtaacaa tccttatctt
    20461 tgtccagatg ctggaaattg agtaattccc gggatacggc aagcgaatga ttgtgtttcc
    20521 aatgcatatt gataaaatga accaacttat tgacttcaca agttggaact tgctttatat
    20581 tataaacact ctccatacat attcttctta aaccgttccg ttatctacat gaatgttttg
    20641 tcctgtaatg ctacatgccg agtctgacaa caagaaaacg acagtctcag caactgaacg
    20701 gaccgatgtg gcagccttta acgaggtgcg tttataaata cgttctttct gttcctcaga
    20761 aagagtggaa ctcatagccg tctccatgaa acccggtacc acaacattgc tacggatacc
    20821 aagaccaccc cattcacggg ccgtattctt agaaaaagct tccaaggttc ctttgctgga
    20881 agcatacatg gccagtcctt tgtaacctgt atgagcagaa atggaagata tgtgaataat
    20941 acaacctttg gtatgatgaa gcaacatatt acgaagtgca tacttggtta tcatcatcgg
    21001 tgtaaataca ttgaccgcat acatggcttg cagcttttcc aaattgaggt tggtcacaat
    21061 atcgtcataa gccatggccg cattgttcac atatccatga agctggatgc cgttgtgtat
    21121 aaattctcta aaaactgtct tgcgtacatt ttcactatca cttaagtcga tacttttgaa
    21181 aaatacacgt ccggcatatt cggtttccaa aaatttaaac tcattggtgt aagagcgggc
    21241 tactccatag acaatatgcc cttgttgtaa aagcgcccgg cagatttcaa gacccactcc
    21301 acgtgagcac ccggttacta agaaattcat aatcgtttta atttacctgt tcttgttaac
    21361 gagaaggatt cgacgaatct gatgcgacgg gggattttaa aatcctgaag actgtctttc
    21421 aggatacggc gaatttcaag ttctgaaagc cgtactcctt cttcaagttg cacctccgca
    21481 caaagtatat tgcccaaaac tgaattggct ttgccgaata ccaaagactg acgaatgcct
    21541 tttatggcat tgagcacatt ctcaacttcg cccggattca ctttatatcc cccaacattg
    21601 atcagctcat tttttctact tttgaatttg aacactccct cttcgcgatt tatccattct
    21661 atcaaatcac cggaatgata ataatcacca tcaaacctga aactgtcgga ttgtcctaac
    21721 agagagcgat gaatcaggag ttcgtcatcg actacctgga acatatcatg aatcgatgca
    21781 ggaatctgaa agttttctcc tttggccgca aacaaggacc ccgcttctgt agaagcatag
    21841 acattgttta tttgagctga cgggaatatc tgacggatga cattataaag atgtccatca
    21901 ctcttttccc cccccaacgt cagacggata accgaagaat aagctctttc atagggcaat
    21961 aatagacgat agaaagtagg agtggcggaa atatgggtta tagagtgttt ttttatcaga
    22021 ttgaagattt cggaacgggt acgattaaat acattaatta atgtattgag attttcaaat
    22081 gcctggaaaa acacttgcaa acctgccata tgcgtaggat tgtaagcata cgcccaaatt
    22141 tgattgttgt acttttctcc ccggcgcaca gagcgagtta aagtctgtat gctgtgcact
    22201 acctttttgg gttgaccggt agtgcctgaa gtaaacatgg ttatttcaga agttgaatgt
    22261 actagcgctt ctatcacttc tcccatggat ggcaaccgct tcacagaaag ggggatagac
    22321 tgattgacca ggctttcatc cacaccatca agttccgcag ggctaagatc tgaatcgagc
    22381 aagacaagcg gaacgtcgtt tgtcaatgcc ttgaccaaat tgccaaaata ggaaaaaagg
    22441 tgatgcgtct ttaataaagg aaaatagttg tcctgattca ggtgacggag caagtcatca
    22501 taagagtact cacattcgcc atcgcataaa aatacagtca tattatatct tacttttgaa
    22561 gttttgagta aacttcaccg atagtattta ccaaaccatc ctcaaaaata tcaatgtcaa
    22621 attcatcctc aattcgaact gtcagttctg ccagatcgaa tgatgtgaat tccaagtcat
    22681 cacgaagatt gtcttcggca tgaagttggg ttatggcaga caattctttt gccaccctga
    22741 tttcatttac tatttccaat actttttctt tcatatcatt cactcgttta aattacattt
    22801 tctggtccag attcttcccc ttttcctcat gttcaaagtt ggggatgaaa cgctttatcg
    22861 ccataaccac ctcttccttg gtaaaatccg gttcggcaaa tatattctcc atttcagtaa
    22921 agaatgcgtc tatctcagcc atcggccgtt tcaccacttc ctcaatcacc cctaggctgc
    22981 aaaaacgatc catattaatt ttttccccag gaacatagaa ctcctcgtag gctttctctc
    23041 ctgtcgtgtc acttttaaaa tacaccacag gataatcctt attgttaaat gccatttccg
    23101 aagcaaattt cttcgcttcc tcatccgttg caaactcttt cttctcgcag ccaaccgctt
    23161 ttatatactc atcacaaatg gaagagaaag tgagcatctg tctttcaccc aactttggga
    23221 agaatatttc accattctta cctagtatgc aggcaagcat acatatctgg ccgctttcct
    23281 ccggagagac aaagtagcgt ttcacatcat tgggtgcagc caacggctgc tttttcatga
    23341 cacgctgtat ccagccatcc ggcaaagaac cgttggaaaa agccacattg gcaaaacggg
    23401 cggtggtcac cttgaacttg gaagaatacg ccataatcat atcttccata atacgtttgc
    23461 tggctcccat gatattcacc ggattggcgg ccttgtcagt ggagacacag aagaagtgcc
    23521 taggcgggta aacggccaac aggtcaagga atctttttgc cttgatatca ttgttttcaa
    23581 tgagtgcctg taccgaatat ttgtccttct cactacggac atgcttgtga gccgaaaaat
    23641 tcgccacaat gtcaaagcct ttctcctcac ggaagatcct ttcaaagata ggatcggcaa
    23701 agttcaaggt atatgcccga tattccgcag gtacatacat gccgtatgtg gaacgcaggt
    23761 cacgtgtcag ttctgccaat ccgttctcgt tcaggtctat tacaatcagt ttggagggct
    23821 tgaacggcaa gactgcttta atgaaagaag aaccgatgga accggcacct cctatgacgc
    23881 atacactttt attccttatt tctgcttgaa gcgtttcttt attagcttca atatctgctg
    23941 caaacatact tgtcggacga caaatcacat ggtctgcaat gaattgctgt aaattaaaca
    24001 tggatttatt aggattagca tctcattttg acacatccta taaagaaaac cgcattaaag
    24061 cagtttcctt ataaattggg tcaaaaattg gattatcttt taatgcttat ttaacgaaaa
    24121 agtaagatat attcccgagc aaagtaagta gacttaaatc gcaaagtaag tgaacttact
    24181 ttgcccacga acatatctta cttttttcca cacttgtcac cggtttttca cctccggtca
    24241 taaccgcttt ctcggtcgtc ttgcccaagc gttattgata cgcgcacgga tattactgac
    24301 agtcttgccc gatacgaaca aaggtgtgag aggaaagaac aacgagataa aacgctcctt
    24361 caccatctct tccgaagtaa tcttcggttc ccgttcgccc atcttaacta taaccctggc
    24421 cagttccacc gcattggtac attctgctat ctgtaccaga tagatacgta aatcctccac
    24481 cttatttata taagagaaaa ggcgcgtagc ctcgggagat aaagcaggtt ccttgtcctt
    24541 gcttacatca tccttctcta gttccgcctc atcaccataa taattctgtg tggcggaagt
    24601 agcattggga agaatctggt tgctgcctcc ataaatgttg aagacgatgc tgaagtgtgt
    24661 ctcattatcc ataagcttat tgtttgaatg attcgtcaac gggtagttaa cggtcagtca
    24721 atagctagtg aacggcagtc aacagttagt aaacgataat aaatagattt ttttacggta
    24781 ttttcccgca ttaattttgt cgtgtcggaa ggatgaacga acatcccgga aacacaaaac
    24841 ttttaaactt tattttatta tgattgatta cagtgtattt atgatgggca acccgatgga
    24901 tgtcgatgcc gcccaaaaag cgtatgcaaa agctcaagtt tctgaaatca tgccattcag
    24961 ccagtttgtc aaacacattg ccgaccacaa tggcgtattc actcgcggaa cggtaaaagg
    25021 tgtaatagcc gatatgtgcg agtgccttgt agagatgctt ctggagggaa agaaagtaca
    25081 actggctgaa ttgggtaatt tctggatttc tataggctcg gaaggtgcgg aagacctgaa
    25141 gaaatttaca gaaagcaaca tcaccgccgt caacattgtg ttcacgccgg gagaagactt
    25201 ccaaaatctt cgttcccgcg ccactttcaa tcccgtagca agccgcatag cccaagccgc
    25261 caccctgaag gccgaaaagg ccggtaaagg cacagtcgac ttggatgccg ccaaaggaaa
    25321 gacctcggct tccacgaatg aaaacaatcc gtcattatga taaaatacca cgttttctcg
    25381 atgggaaatg cgtccgacag gacgatgccc aagaaagcat atgcaaagtg tgtggccaac
    25441 gaaaaggttt cgcataagaa actcgtaaag aaagtgacgg aacatctccg ctttttctca
    25501 cacggcatga tggaagcggt gctggaggaa gtcttcaacc gcctgtccga gcatcttgcc
    25561 caaggcgacc gagtcaccct ggacggcctc ggaacattca gtgtctccct gaaatgcgaa
    25621 ggagccgctt cggaggcttt gttctccaag aagaacatca agggcgcgca catcgtgttt
    25681 gccccgtgtc gcaaactcaa ggaaacattt gcagatatgg aatataaaat ggctccacga
    25741 atcttttaac gtcatggaac ttatattatt catctattta aagacaaagc gtatgaaaaa
    25801 gaactggaaa aatgtactgc tgtacatcgt ccgcatcatt gagctgctta ttacaggcgc
    25861 tgccggagga gcgcttggaa gcggtttatg agaacggttt cgttgattat cgtgcactgc
    25921 tctgccaaca aggcgggcag tgccttgcga gcagaggaca ttgaccgcta ccatcgttca
    25981 ttgggctgga agtgctgtgg ttaccactat gtgattccta cagacggaac tatagaagcc
    26041 ggacgcccac cgaaaatgat cggcgcacat tgcaaaagcc acaacagtca cagtataggt
    26101 atatgctata taggtggtct ggatgccgac ggaaagactc cgaaggatac ccggacggaa
    26161 gcacaaaagg tagctctgag aaaactgatt gaacatctgc atcagcgtta tcccaaggca
    26221 ttgattgtcg gtcatcatga cttgaatccg caaaaaacct gtccctgttt caatgtcact
    26281 gctgaatata tagatttgca accttagttg cgtctgtagt cttatctgcc atccatcgtc
    26341 ctgcaaggga tgtgtggatg gctttaatta aactaatcaa ttttttcaaa cggaaacgca
    26401 tgaagatagc tcacagccac cgtcatattt ccgaaagcga ataccagcct tgtattgcgg
    26461 tgcaaacgca tgatgcatcc ttccttcccc cggaaaacac caccggtgat acggattcgt
    26521 tgctttttct gaagatagtc ctccaaaggc cggttcatca gctcgatatt gtaaggcatg
    26581 gattcataca aatagataaa ttcttccatc tgacggtgag ggattaccgc cgcacggtgg
    26641 gtgttatagt ccgtcaccag atactggcgg ggaagcatgg cagacagaat acattccaac
    26701 tgccccaagg gggcacatac aaacagccaa ccgttgcctt caattccttt ctcgtccgtc
    26761 aacgtattca gtttttggat ggagccggta gcaaaagcct ctttcacgat ccgtgcagag
    26821 tcacggcgca cggtatattc ctctttggta taagcacatt gctcgaaacg ttttctatga
    26881 tcggtggcag tgtaagaaaa caccttgaaa caaaaaaatc tctcttctac ggtacctgat
    26941 ggtgtacgaa gccgaacagc tttcctgcca ctgaaaacac tgatatagcg tttcagttct
    27001 ttgttggaaa gatacaggta ataccaactg aattcaggat attcttttcc tattcccgcc
    27061 attggcgtga ttccttcatt tgaccccagg tctgagccgg aagcgattga actgcagagc
    27121 agtaacttag gcgcttcgcc cgttatgtct tgatttgaaa ggaacgcttg attttcaagc
    27181 tccatactat tttctgttac catcaaaaca ttacttttta tgtatgtctt tttggggttc
    27241 tcttagtaag agaaccccaa aaagacatat actgctgaca ataaaatatt tacgcataat
    27301 cagagatgga taatttgcaa acaaatatca taagaatcct tatcagagac tgattcctga
    27361 ataaaatatt tccgtatttg aattattata gctacatttg cagcggaatg gggttctctt
    27421 actaagagaa ctccattttt tttattctaa cacattcatt ttcaagacaa atccaagaaa
    27481 gcagaaaaag ggatacataa attccttttc cgcactcatc gaaaggacaa acgataaaac
    27541 acaaaagcgg ccacttacga taaaaatcga aagtgaccgc taaaaagaga tttatttctc
    27601 tgatataagg atctatcagt ccagggttac ttcaccacaa accctctctt atccagataa
    27661 gctttgaatt tatgcaaata ttcttcatcc ggaccatcaa agaaggatac accggatgcc
    27721 ccgttattgt atgcttcatc cagcacctct tcaaaattgt ccttaatatc accaaacatc
    27781 agtccggcat atatcttggc acgaccattc accgtttcaa cgctttcctt taccgaacgc
    27841 ccgatccatt caggaccttc ataatagaat ttattataaa tcatcggata ataagcatcc
    27901 agcgtccatt ctccccaatc ttggcgtacc atgtgacgag ccatggacgg tcccgggaat
    27961 acggcggcag aaatagcttt atgatccgct ttcactgctt tagtgatggc atccaccaca
    28021 cgagtgatgg catccagacg gaaattaatc caactctggt tttccatcgg atactttaat
    28081 tccaacggat cctgtcctgt tttagcttta aacaattcac ggcatacatc acaataacaa
    28141 tagtcatatt ccggcaactc ttctttctgc tcgataccat agtttttcca taagctgaca
    28201 ggcaagatta catccggcat acggacataa tccagatgaa caccatccac gtagggttta
    28261 tgagcttcct ttacatagtc ttctgccaga tattcggcca caccttggtg attagggcac
    28321 aagaagcgat aataatccac gtaggccggt ttgtcgtgac aagactcgcc tttacggttc
    28381 acggcatacc agtcgggatg cttgtccagc agttccctgc ggttcatcgt ccatttccaa
    28441 taatgcgcct ccaatccggc ttctttgcag aggcggtaaa tattctcatt gtatccctcg
    28501 aacatgacac ccgaaatacc acattctttc aacaacgcaa accacttttg ccattcggca
    28561 tccgaacggt tattcagacg catccacaac cagtttttaa cttcacgggc aggtatcttt
    28621 tctgtccgga aacgtccttc attattgatc acataacgga ttccttcagc aggattggtt
    28681 atagctatct gatacgtgtt ctgagtcgct tccaccgcaa tccgggcatc agccggaaga
    28741 tctttcaact ctttatcagt caaaaagaat tgttctgtgg cacgcagata attatgttgt
    28801 ttactataat tatcctgttg tgcgtagaac atggcccaca gcaatttata aatggcctga
    28861 ttgtacgggt aaaccaactc atcttgcgag gttcccactt tcttgtctac gaaataaaga
    28921 tatccccaac ggtcgggcat gtgcatatcg attcttccgg taggagtcca tacccaattt
    28981 tcctcgggtc ctttctcctt cagccactgt acacgcgaaa agttgatgcg ccaggtattg
    29041 ccagccttca acggattgtt aaagttcatg gtcagcgcct gatgaggaat ggccatttcc
    29101 acactccaat acttatcttt atcttttgat ttattcagtg taccttcgca atggatggca
    29161 gtcttcaatc cggggcagtc ccattgcacc atgaaatttc cacccgaacg ataaggtttg
    29221 tccagcatca gatcgaaaat cacgccacgc gcattggttt ctatttcaaa ataattgtgt
    29281 ccgtcgctat ccggatcaat aaacacttca aagtcattgt cataatagat gatggtatca
    29341 cgctgggtaa gacgcgcctt gatatcctct tcttgaagaa cagctcctac atataaaaat
    29401 tcatcatccc acagcatctt ggcggtagtt tcatatttgg gagtcgggaa tccttctccg
    29461 cttatatcta caaacggggc agtagacgcc gccttgttcc aggaactttc attcagttta
    29521 ccatctattt tcaactttcc atccggacga taacatacat aagtacgcgg ttcggtcaga
    29581 aaacgctcat attgttcaaa aaggctttgt gccattgccg gaaaagtaac cagcagaagt
    29641 aacagggtat aaataagttt cttcatgtat ttttcagatt caagttagtt attatcttgc
    29701 acttgtccca ctccgcgata tagtttgatc ggtccatcca gcaacacggc cagcacggta
    29761 atctgctcat cctgcacctg ttggggtaca tcaatgtaga gattacccgg cactgaattc
    29821 caataatttt tattgtagac cttgtaattc aacatagctc cgttaccaac cacccatata
    29881 cggttcactt tgttcatcag cccttttact tccaccggac cgttaggttt gtaaggaagg
    29941 tataaataca aaatatcccc cgccttattc agtgtggtat atccctggaa atgctcggta
    30001 ggaatacctg cgcgagtttc ataaatagct tctttatgct tcttggtcca tcggccgaac
    30061 tccttcaaca cagcgatctg ttcttcagga atggaaccgt cctctttggg accgatatcc
    30121 aataaaagat taccacccat gctcaggcag tctacaaatg tacgaagcag gatatagggt
    30181 gatttatagt tgctgtctgt atgctgatat ccccatgaat cattcatggt catacaaagt
    30241 tcccaatatt tatcttcggg acgcaccacc ggcactcctt gttcgggagt ggcatagtca
    30301 ccatacccct gtatacgcga gttgataatc acatttttat tatccgaacg aagcaaatct
    30361 acaattcctt tggaattcca tgcttccgaa ctttgctccc aatctccgtc aaaccaatac
    30421 agatccggtt tccaggtctt gttcagctcc gccaattgtc cgaaattgaa cttgttgaat
    30481 cgggcccaac gttcaggatc atttttataa cgtacttccg tacgggtttt gttgggataa
    30541 tcaggatgcg accagtccaa taaagaataa tagaaaccaa gcttcaatcc ttgttttctc
    30601 acttccttta caaagggagc gataaggtca cgttttgccg gagtgctttt cacgacgctg
    30661 atatctccta ctttggtatc ccataacgca actccgtcat ggtgcttggt ggttatcact
    30721 gtgtatttgg ccccactctc tttgatcaga tccacccagt ttttcggatc atacttggag
    30781 gctgtgaaac ctttttcctg ctccatgtat tcatcgtagg gcaggtagtt gttaaagaag
    30841 gaccagcttt cggacactcc tctaacagaa taaatccccc aatggataaa aatacccaac
    30901 ttggcttgtg aaaaccattc cattcttttg tccttttgct cggctgtttc agtctgcggc
    30961 gtatcctgtg cccgtaaagg ggaagctgca atcagcaaac ccaggaacgc taacgataat
    31021 cggttctttt tcatatataa taggtttgat tagttaggat agcatgtcag tattattaaa
    31081 atttacagct atataatgga caaagataat gtatttttat attttattct atctttgcac
    31141 ccctaaaaca gaacaaatat gagcgcaaag aaaaagaaac aatccaatag ttccctgaga
    31201 gtcatcatta ttttagtatt actgggactt ttggcatata aacatcaatt gtttgacggg
    31261 aaactgcttg aaaatatccc cactatcgaa agcaatgaag aaaagccaga aatactgacc
    31321 tcgccccaac atggcggtgc attggaaatc ccgacgatgc aatcgggcac aggcggacag
    31381 atattgaaac gtaaaggata taccctatct tataatgccg attacaaaac tccacaatgg
    31441 gtagcatggg agcttactaa aaaagaaaca aaaggaaaag aagggcgaac agacaaattc
    31501 ttgcccgacc cggacgtacg tggagccaaa gcatatacgg gagattatac aaaatcagga
    31561 tacgaccggg gacacatggc ccctgccgcc gatatgaaat ggagcaaaca agccatgaaa
    31621 gaatcttttt atatgagcaa catttgtccg caaaacccta atctgaaccg cggtgactgg
    31681 aatgacctgg aggaaaagtc acgccaatgg gcaaaaaaat atggagcagt gtacattgcc
    31741 tgcggcccca tatatgatac taaacgcccc aaacgaatcg gcaacaacaa agtggcagtc
    31801 ccccatgctt tctataaagt catattgata aatgataaga aaaatccgca agccatagga
    31861 tttatcttcc ccaacagcgc cggacataag ccgctgaaga aatatatagt aacagtggac
    31921 agcgtagaga aaagaacgaa tatagatttc ttccctgccc tgccggatga ggtagaaaac
    31981 agaattgaag cagagagggt acaagagtta ccgtaaccca tcacatacgt acgtgtggcg
    32041 caatatatac gtatgcatag ccctacactg acgtatgtga agggctacac gtacgtacgt
    32101 gatttatttc acttccaaca ccacgataga cttggcagga agagtcactt tcaagcttcc
    32161 cttattaacc ttggctccgg taaattcttt cggggcaacc acactcggtt tctcgaaact
    32221 attgtaatca cctatattgt tagcggtcaa aatacggccg gtaacactct tagctttcac
    32281 ctcacccaga ttcaactcta tttcctgcga ttcctgcaaa tctacattag acaaggaaat
    32341 atgaataaaa ccgtttgcat cccgtgaagc ggtagcactt accatcggaa caatgcggtc
    32401 gtcacgtacc accttgcgtt cacagttcag ttccaaagga agataagtag catcttgatg
    32461 cactttatac atttcaaaga catgataggt cggtgtcaaa accatcttgt cttccttggt
    32521 cagaatcata gattgaagca c
//
