LOCUS       gnlProkkaKCEKGKEI_336  32540 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCEKGKEI_336.
ACCESSION   gnlProkkaKCEKGKEI_336
VERSION     gnlProkkaKCEKGKEI_336
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:49:03
            Original ID  :: gnl|Prokka|KCEKGKEI_336
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 22628
            Orig. end    :: 55168
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..32540
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:22540]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..22540
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..32540
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..32540
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             complement(1063..1863)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 117.2; E-value:
                     1.3e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_19"
                     /transl_table=11
                     /translation="MKVVLLAGGFGSRISEESQFKPKPMIEICGMPILWHIMKEYAYYG
                     YNEFIICAGYKQEYIKEWFANYFLYNSDVSFNFRNGKNEITVHHSNLEPWKVTIVDTGY
                     NTLTGGRIKRIKEYVNNETFMMTYGDGVCDVDINKLVAFHKKHGKIATLTAVIQAQDKG
                     VLNIDENNSIRSFREKNINDGVPINAGYMVLEPRVFDYIEGDQTIFEKEPLNKLATEGE
                     LMSYTHKGFWQCMDNIREKNLLEQLLIDGVAPWKKWEREIPIIK"
     CDS             complement(1860..2336)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_20"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 2.3e-09,
                     bitscore: 30.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNITIDGVLLTPLKQITHPKGDVFHAMKCVDPGFEGFGEVYFSS
                     VLQGLVKAWKRHSRMTLNLVCIVGKIHFVLYDGRENSSTFGKYMEVILSPELPELYRRI
                     TIPAGVWMGFVGIGEGKSILLNVANIPHDPLEQVNIPIEESDIKFDFNKISRSI"
     CDS             complement(2346..3446)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     100.7; E-value: 1.7e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_21"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.3e-10, bitscore:
                     31.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.9e-14,
                     bitscore: 45.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFSNIYKNKKVIITGNTGFKGTWLSTWLKMMGAEVYGYSIGVPT
                     TPSMFDTLHLEDKICQHYGDIRNKREFNDFVQEVKPDFLIHLAAQALVLTSYREPFETM
                     TTNIVGTAVVCEAVMNIDWNCTCVLITSDKAYDNVEWIWGYRETDGIGGKDIYSGSKGA
                     AELVIKSYWHSFIKKMPNIKFGVARAGNVIGGGDWAKDRIIVDCVKAFSEGKTVEIRSP
                     KATRPWQHVLEPLSGYLTLAQYLCEGKCENGESYNFGPRAEQTKTVFELFQDLATLWGL
                     DKNKAAKLTGNVPFEEATLLKLNCDKALAYLHWHSTLHYDECVNFIAEWYRAFYVEQAK
                     DMFALTEKQINAYMEAAKKQNLDWAK"
     CDS             complement(3436..4698)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     162.8; E-value: 2.2e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_22"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.3e-52,
                     bitscore: 172.4, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRLLFTSEISSFISPSIDISEKQSDYEALIEAPNLDYVNRYEKE
                     LSQFLGGGHVVTFASGRMSFYSLLKSWGIREGDEVALTGFTCAVMANAVLRTGATPIYV
                     DIDKDTLGMSAESLVSKITNRTKVVVAQHSFGIPCKIDKIKEIAKSHSCYLVEDCALTF
                     GSKYKSIIVGNYGDAAIFSTDHTKPLNTLIGGFVYTNDIDIATSIRAMRDDCGDLSNEH
                     QRMILKTYIDEHRIETVNHKIYIMRNYKKALMNKLHIHNEISPYLELETSAKIAINPYY
                     SYPAKLPSVLAKIGLHVLEQYKANIHQRQSWLKEILQVVEKKEDMPAAYYDTGCDIIPL
                     RIAYSTYFALTVFSYIDDWIWFKTPIVATKENICDFGYHWGGCPVAEKIGKSIMNLPVI
                     IDSKQQNIFLRNIKKTYSYGI"
     CDS             complement(4762..6300)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_23"
                     /sec_met_domain="Polysacc_synt (E-value: 1.4e-08, bitscore:
                     27.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPMSISYRGKYFRIYIWQGLSIILGFLSLFIVMPLLSGNKTLFG
                     IYSVCTSLTIFFSYADLGFISSGLKYAAEYYIRGDRKNEIRTIGFTAFIMLSMFMLIAL
                     LFGIISIFPQILMPELEPDRENFYTARYLLILLSVSCPVIIGQRILNMIYSIRVEDYKL
                     QRISAVGSILKILSVFFFFGSENYLLVPYFAFVQFINLSVVLMAAFQVRKYQYSFVEFL
                     KAIRFDRIIFDKEKGLTGASFISILSWVLFYEFDQIAISNFVGLEAVAVYGIAFSALTF
                     VRTFVSLLYSPYSSRYNHLIGENDRVGLMKFVNRMLLMLSPMVVLPIVGLSMLSEPFII
                     SWVGFNYEESSSILSLLVFCFFPCFLSNPSSSYFIAIEKTTLLNRFNIFQPILYWLLIF
                     FTIDKWGVFSFAISKGLIPIFLGILYWYSLYRDFAKNAGQIVSLFLILKTLFLPLIVLL
                     VLSTLVKPYMAYEYNKISLCYNLLVMGLIVLISILVSVCCNREMYSLVKSIIRR"
     CDS             complement(6297..7940)
                     /locus_tag="ctg68_24"
                     /transl_table=11
                     /translation="MILNLNELTLEQSKLKAKLKKNVIADYNALTEQLIDYNRDSLEWL
                     VCNVNSRSTVFSSMLAELESLRLISELISSGEIIEEIIVDNDELRKTISNLYPKINVHG
                     KTSSLKNNIRLWKNNIRYGIWSLCSWLSGSKERRNKVCRGGRLTIIDTFIAKKVDAYWD
                     RFYGNSVDKLIDAQKEQIYFMPLYLPFASKKQLDIIVANSKENLFFMSDFLLFKDYLYA
                     WRYMGRFEKPDFASYTYQGFSLQWLLGKAYKESNQSYFYYAILMERAIMRMKELDVDIC
                     LFVDWFENQSYDKSVYYAMHQYYPEAKVHGYMGFIADSTIFPHIIASNKELFCHIAPKD
                     IYLCSSYLLKFYQNYNGYKHIAPALRNQEIYSSHRSTKPHDKFTLLVPFALDNYDMEYK
                     YELLTDFIKSSNANINILLKPHPDANSSWMVSCTNKAGGKLEVVKGNVNSFLLKADAIL
                     AANTSVMFEALSLGIPVINLKDPLSIILFDKIEEVNEVLWYTANNLAELSDAIVRILNL
                     NIEDAMTEGYRLRNYFFTKLEPQLIFQLFT"
     CDS             complement(7941..9098)
                     /locus_tag="ctg68_25"
                     /transl_table=11
                     /translation="MSNQNLPKLFFFNIEPWKEVYNDRFLLKQLQEKGFPIEYVWIGPL
                     VGLLSNVSSKGCETIPKSWKEIQRIINLDRNKDAILISLMPVFAPCLKLFRILSKAKQK
                     NVGYFNIGSMHLPLPKNRMEHRLKLLFNPIRVRYYFIHRSIPLLRKIGYLKDFDYAVTQ
                     GVHSINSASQLISDKTQKITIVDYDIEHFNKVDKMERYNDRKYIVFIDAYMPFHPDFEV
                     TASGHIDPEQYFKSVNNYLKRVEDKYGLPVVIAAHPSAQKYHEHNYFDGRPVLFGKTAE
                     LCKGCAWAINHLSTAITFLIIQHKPIKFITTDEVVNKYGIAAELSYSGFFQSPLVNIDA
                     EDADISVPVVFDSVYDEFIDKYLYTKDEIGKASADLLSEALLKIK"
     CDS             complement(9316..10008)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207:inositol monophosphatase (Score: 61.1; E-value:
                     2.3e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_26"
                     /transl_table=11
                     /translation="MNEPDICRSIHELIMLHLPEILSLRNTSELKSDHTFVSKGDKLCE
                     KLIFDFLDSNLKDYLVISEETETNLSRLEEVEYVITVDPIDGTENFVSGLKEWGVGISV
                     YKGMRHYQSMIMLPELGIRLCTGDQFSKIIGSRICGLSSYMQPEDFKRLEQGSEYRIMG
                     CCMYNMYNVIRGCYRQFLHLKGCYSWDILPGMNLALEQGLDVELEGEKYGGEFLYPGVK
                     YRFNIKAG"
     CDS             complement(10001..11578)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 64.8; E-value:
                     1.2e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_27"
                     /sec_met_domain="HMGL-like (E-value: 1.8e-22, bitscore:
                     73.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKIQLLDCTLRDGGYINNFRFGKYAIRKILQQLTHAGLDIVECG
                     FLEDGEYDEDTSIFNAAEQIASLLPNEHGRTMFVAMVCYGEYDLSQLSPCTRNSIDGIR
                     VTFHYDEVEGALEYCREIKEKGYKVFVQPVGTSSYTDIQLLHLIEKVNELQPYSFYLVD
                     TLGLMHKNDIARFFYLINTNLDKSINMGFHSHNNLQLSFSNSQEFFEYVGDRVISLDAS
                     IYGMGRGAGNLNTELIANYVNDREGHMYAIEPLLEVVDEFIIHIRQKHEWGYTVPYYLA
                     AINGCHPNYASYLAQKQTLAVKEISAILHMIPVEKRSLYNKELVNRIYLEYQSHEVDDT
                     YVLKNLKEKIGGRNIILMAPGGSITDCYDEIVQKQNSENCLLISVTFVPDFMDCDFTFL
                     ANAKRYATTFNPMKKEVSLIYTSNIRANQEQSGYCVNYVSLLNEVDIIRDNSALMALNL
                     LQKLSPRKVYLAGMDGYSMKKGNYYQERLNLIQDRDYVLEMNKAIKHRISEIGKVMDIE
                     FLTPSLYE"
     CDS             complement(11575..12327)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_28"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.1e-14, bitscore:
                     46.0, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIAVIPARYKSTRFEGKPLVNLCGKPMIWWVHHQLCQVKGLSE
                     IYVATDDERIGKVCSDYGIKYVMTSDSHPTHLDRLAEFAENIESDFYININGDEPLMMP
                     EYVERLLPTSDLNPADFYFANAMTKIKKTVEVADISRIKVVTDNLGYAMYMARTPIPYP
                     KASSDFDYMKFVGIQCFSRSALLFCKDNKRGKIESIEDIDEYRFLENGKKIKFVEIPAE
                     TLSVDTQADVKIVTEVLERRIKNKEIVL"
     CDS             complement(12347..13387)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 145; E-value:
                     4.4e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_29"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.3e-11, bitscore:
                     38.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNHSHIISQSLSIIDSIRCINEIHGEPLVLFVVDAEKRMQGTLTD
                     GDVRRALIKGIDVDAPISEAMHRNFNFLRRGVNDGVEDIHRQRDLKMRLVPVLDEENHI
                     CEIINLEHYITKLPIDAVLMAGGKGERLRPLTEKTPKPLIKVGDKCIIDYNIDRLLSYG
                     LNHISVTVNYLGNQIEEHFREERDGVKIVTVREPKYLGTIGSIKFVETFYNDTVLVMNS
                     DLFTNIDFEDFFLHFCQHDADMSVAAVPYVVKVPYGVFNLEGREIKGVTEKPTISYYAN
                     AGIYLIKRKLFDLIPDDIFFNATDFMDKLIEQGYKVIRYPISGYWLDIGQHDELARARE
                     MVKHLK"
     CDS             complement(13398..14087)
                     /locus_tag="ctg68_30"
                     /transl_table=11
                     /translation="MNILVIIPVRGGSKGIPGKNIKILGGKPLIGYTIDAARAVTDNDH
                     ICVSTDDDRIIQVVEQYGLKVPFKRPEELATDTAGTYEVLLHALNYYESKGETFDVVVL
                     LQATSPFRTGNHIKEALKLYSKEIDMVVSVKETDSNPYYICFEDDANGMLHISKGDGHY
                     TRRQDCPPVYEYNGAIYIINPDSLKRMPLYKFTKRVKYVMDRGHSIDLDTMIDWQIAEY
                     MINNHLI"
     CDS             complement(14092..15246)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_31"
                     /sec_met_domain="Epimerase_2 (E-value: 4.1e-88, bitscore:
                     288.8, seeds: 187, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKICVVTGTRAEYGLLSRLMRLIDESADCQLQVIATNMHLLPEY
                     GNTYQEIECDGFHIDAKVPMRKLSDDSYGVIDSMAEEMKGMNEALLRLHPDMVVILGDR
                     YEMLVTATVAMLQRIPIAHLHGGEISEGAVDDSIRHAITKMSSLHFTSTEDYRRRVIQL
                     GEQPDRVFYVGAIGVENLKQIPLMSRQDLEDSLNFTFDRKIILVTYHPVTLGNRSPKDE
                     IDDFLFALDTFPGLKVLFTMPNSDEGSEVIRQAIEGYCSRNSDRCSCYSSLGLKRYLSA
                     LQYVTAVVGNSSSGLLEVPSVHIPTLNIGDRQKGRVHGNSVLDCASDKESIIRGLTMVL
                     SLSFKEVALKASNPYEKENTVQSVFDVISTYPLDELKRKSFYNL"
     CDS             complement(15243..16250)
                     /locus_tag="ctg68_32"
                     /transl_table=11
                     /translation="MKHTLIIAEAGVNHNGSLTIAKKLIKVAAEAGVDYVKFQSFKAEN
                     LVTKSAKQAEYQQHNIGDGNTSQYNMLKKLELSHEQHVELLTYCREKGVKFLSTAFDFE
                     SIDYLASLNLGFWKIPSGEVTNYPYLVKIAQTGFPVIMSTGMCEMEEIQSAFDVLTAHG
                     LQKEQITLLHCNTEYPTPMYDVNLSAMNEMRSQFGVSVGYSDHTQGIEVPIAAVAMGAE
                     IIEKHFTLDRSLPGPDHKASLEPDELKAMVTAIRNIEQAIGMGYKTVSASERKNKAVAR
                     KSIVAARDIKKGELFTEENLTVKRPGNGINPMRWPEIIGKRAVRDFNEDELIEI"
     CDS             complement(16250..17152)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 171.8;
                     E-value: 2.7e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_33"
                     /transl_table=11
                     /translation="MKKFRIGYFADGLWGHFTLDTLLKDETLEIVFIVPRNDTKDEYLK
                     NKALEYGIDYLMPVKVNSEEFYQKAINYGCDLFVSMSYNQIFKRKIFDLPPCKTINCHA
                     GKLPFYRGRNILNWVLINDEKEFGITVHYVDEGIDTGDIILQRTFPITDADSYNTLLQV
                     AYEACPKILYQAIKDIQAGKAKRVPQDMISHHGLYCGMRQIGDELIDWQMTSRELFNFV
                     RSICQPGPMATTFCKGIPVLINQVEYNENYPQYKGIPGQVIGLEHACPIVKTKDSYIKI
                     VQYESECKLKVGDRLQTNQ"
     CDS             complement(17170..17379)
                     /locus_tag="ctg68_34"
                     /transl_table=11
                     /translation="MKRPLILVGGGGHCKSVIEAAESAGYLIKRILDIPSQVGEEVLGY
                     TIIGTDNDSMYCSSMNTLSCEKAA"
     CDS             complement(17387..18532)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     270.3; E-value: 4.7e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_35"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.7e-88,
                     bitscore: 289.8, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNAEICEFIHHLFGTQDFVPLSAPKFIGNEKKYLNECIDTTFVS
                     SVGAFVDRFEHDMAVYTGAKRAVVCVSGTNALHMAMLLVGVERDDEVLTQALTFIATCN
                     AVSYIGAYPVFIDVDKETMGLSPRAVKAWLERNAELKEGVCYNKRTGRRVKACIPMHTF
                     GHPVKIDELADICREWHIELVEDAAESIGSFYKGRHTGTFGKVGAISFNGNKTITTGGG
                     GMLLFQDEELGAYAKHLTTQAKIPHRWEFRHDHIGYNYRMPNINAALGCAQLENLDRYV
                     ADKRETAARYVEFFKGKEDITFFTEPADCKSNYWLNAVVLKDKVAQLEFLEYTNDHGVM
                     TRPVWELMNRLPMFEHCETDGLENTEWLADRVVNIPSSVRL"
     CDS             complement(18554..19543)
                     /locus_tag="ctg68_36"
                     /transl_table=11
                     /translation="MNADKLTVVMYHYVRDLQNSRYPQIKGCDVRLFKEQIKFLQKHYN
                     FVTIEQVINAYRGGHSDKLPPHAVLLSFDDAYADHFEYVFPILEHEHIQGAFYPPVKAV
                     TEHTVLDVNKIHFILASTPEDNFPVLLNEIKQLILANTDEFGLKSYDEYFKELAVANRF
                     DPAEVIFVKRLLQVALPEALRKRMADILFEKIVGIEESAFSRELYMSVDQIKCMVDCGM
                     HIGSHGYDHYWLGSLPREKQEFEIKKSIEFINEVGGDVDNWTICYPYGDRNKETIQLLK
                     ENGCKLGMTTDVDLADLTDHEGDAIFNLPRLDTNDLPKDANAPVNQWY"
     CDS             complement(19561..20595)
                     /locus_tag="ctg68_37"
                     /transl_table=11
                     /translation="MESVYNIKQVPTCEVNKLVHFINMHWKHNHSLAVSRELLNFQHLD
                     KDKDCYNFLVAENKETGEYDALIGFIPVAQYDKDLVGNGDYWGAIWKIRDDIYNSELNT
                     VAFFLWRSLFKLPYFHSYAAIGISDIARQIYKVSRIPVDYLRQYYLRNSRIKNYQIAFF
                     PVGSQNGSAISDESYTLQLVHNVEWDKIAIKGEYAPFKTPLYFCHRFAEHPVYHYQFVE
                     VKKNGILESVWTVRIMRVGDSSAFRIVDVLGKLPNTCVKGQLLDILYQTGAEYMDFMNF
                     GLPEETFTKMGFELLDLDGETIVPNYFEPFEQRNVKIEIAYKTKGDNYVAFKADSDQDR
                     PNIL"
     CDS             complement(20607..21329)
                     /NRPS_PKS="Domain: PKS_KR (2-166). E-value: 1.8e-07. Score:
                     23.0. Matches aSDomain: nrpspksdomains_ctg68_38_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     156.9; E-value: 1.1e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_38"
                     /transl_table=11
                     /translation="MNFLVTGCSRGVGLEICRALLQQGHIVYGVARSYTNEFKFLETEY
                     AGRVFFKSIDLSDSENVRKTVFREFIHNGIQLHGYVNNAAMAYDDIVTNLNLEKLQAMY
                     AVNVFTPMMITKYALRNMLLHHTKGCIIHISSISAHTGYKGLAMYASSKGTLEAFSKNT
                     AREWGGLGIRSNVVVPGFMETAMSSTLSEEQKERIYKRTSLKAATSVRSVAETVVFLLS
                     DSACSITGQNIHVDNGTV"
     aSDomain        complement(20832..21323)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg68_38_PKS_KR.1"
                     /evalue="1.80E-07"
                     /label="ctg68_38_PKS_KR.1"
                     /locus_tag="ctg68_38"
                     /protein_end="166"
                     /protein_start="2"
                     /score="23.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="FLVTGCSRGVGLEICRALLQQGHIVYGVARSYTNEFKFLETEYAG
                     RVFFKSIDLSDSENVRKTVFREFIHNGIQLHGYVNNAAMAYDDIVTNLNLEKLQAMYAV
                     NVFTPMMITKYALRNMLLHHTKGCIIHISSISAHTGYKGLAMYASSKGTLEAFSKNTAR
                     E"
     CDS_motif       complement(21258..21320)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg68_38_0001"
                     /evalue="7.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg68_38"
                     /protein_end="24"
                     /protein_start="3"
                     /score="18.7"
                     /tool="antismash"
                     /translation="LVTGCSRGVGLEICRALLQQG"
     CDS             complement(21326..22540)
                     /NRPS_PKS="Domain: AMP-binding (99-316). E-value: 4e-27.
                     Score: 86.6. Matches aSDomain:
                     nrpspksdomains_ctg68_39_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 66.9;
                     E-value: 2e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_39"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-20, bitscore:
                     66.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVFLCDGECEYSYDDLLRHLNQDNYFPLLKTHHLFSYFGNLVKA
                     LTNDVPLVLLDSDLSPAELDGVDESLVNQSIPLSVKRLPSMGEVIEALVHSTSEITMFT
                     SGTTGQPKKVVHSIQTLTRSVRRGEKYNNQIWAYAYNPTHMAGLQVFFQAFENLNTLIN
                     VFNRTRSEIFNLIKKHSITHISATPTFYRLLLPYERAYSSVIRLTLGGEKSDGHLYNVI
                     RQIFPSAQINNVYASTEAGSLFAAKGENFQIPASIHDMFQVVDDELLIHRSLLGQSDSF
                     RFDGDYYHSGDLIEWINREEGVFKFKSRKNELINVGGYKVNPGEVENVLNAIKGIRQSL
                     VFGKANSVLGNILCAEVQLEEGVRLSELEIRRILKDSLQDFKIPRRIRFVESFSLTRTG
                     KLKRL"
     CDS_motif       complement(21560..21622)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg68_39_0002"
                     /evalue="2.00E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg68_39"
                     /protein_end="327"
                     /protein_start="306"
                     /score="11.0"
                     /tool="antismash"
                     /translation="KSRKNELINVGGYKVNPGEVE"
     aSDomain        complement(21593..22243)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg68_39_AMP-binding.1"
                     /evalue="4.00E-27"
                     /label="ctg68_39_AMP-binding.1"
                     /locus_tag="ctg68_39"
                     /protein_end="316"
                     /protein_start="99"
                     /score="86.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ITMFTSGTTGQPKKVVHSIQTLTRSVRRGEKYNNQIWAYAYNPTH
                     MAGLQVFFQAFENLNTLINVFNRTRSEIFNLIKKHSITHISATPTFYRLLLPYERAYSS
                     VIRLTLGGEKSDGHLYNVIRQIFPSAQINNVYASTEAGSLFAAKGENFQIPASIHDMFQ
                     VVDDELLIHRSLLGQSDSFRFDGDYYHSGDLIEWINREEGVFKFKSRKNELINV"
     CDS_motif       complement(22193..22237)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg68_39_0001"
                     /evalue="4.10E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg68_39"
                     /protein_end="116"
                     /protein_start="101"
                     /score="16.4"
                     /tool="antismash"
                     /translation="MFTSGTTGQPKKVVH"
     CDS             complement(22549..22773)
                     /NRPS_PKS="Domain: PP-binding (4-56). E-value: 9.8e-09.
                     Score: 27.6. Matches aSDomain:
                     nrpspksdomains_ctg68_40_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_40"
                     /sec_met_domain="PP-binding (E-value: 2.5e-08, bitscore:
                     27.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKVLEIVNEIRVAKELSAITQLHAEDNLRDDLEFTSFDLAELT
                     VRIEDEFDIDIFEDGLVNTIGEVYSKLQK"
     aSDomain        complement(22606..22761)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg68_40_PP-binding.1"
                     /evalue="9.80E-09"
                     /label="ctg68_40_PP-binding.1"
                     /locus_tag="ctg68_40"
                     /protein_end="56"
                     /protein_start="4"
                     /score="27.6"
                     /tool="antismash"
                     /translation="VLEIVNEIRVAKELSAITQLHAEDNLRDDLEFTSFDLAELTVRIE
                     DEFDIDI"
     CDS             complement(22792..24000)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_41"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.8e-39,
                     bitscore: 128.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFNLQQFIADHVICRPTSMFAADIEANKETLQAEIRNKSVCVIGG
                     AGSIGSSFIKAVLPFKPSKLIVIDLNENGLAELTRDLRSTYGMYVPAEYRAYTLNFADP
                     IFERIFREEKGFDIVANFSAHKHVRSEKDKYSVQALIENNDIKAKRFLDLLAVYPPRHF
                     FCVSTDKAANPVNIMGASKRIMEDMIMAYSSKFKVTTARFANVAFSNGSLPDGWIQRVM
                     KKQPLAAPNDVKRYFVSPEESGQICMLACILGKNGEIFFPKLGERQMLTFSSICDEYIK
                     AVGCEKKEFATDEEAKKFASEMAFNNKDYPVVYFKSDTTGEKAYEEFYVPGEKINMDRF
                     CSLGVIEEVVKRPMAEIDAFFTEMENIFAEPDFTKEEVVMAIKRFIPNFEHEEKGKNLD
                     QKM"
     CDS             complement(24237..24671)
                     /locus_tag="ctg68_42"
                     /transl_table=11
                     /translation="MDNETHFSIVFNIYGGSNQILPNATSATQNYYGDEAELEKDDVSK
                     DKEPALSPEATRLFSYINKVEDLRIYLVQIAECTNAVELARVIVKMGEREPKITSEEMV
                     KERFISLFFPLTPLFVSGKTVSNIRARINNAWARRPRKRL"
     CDS             24859..25359
                     /locus_tag="ctg68_43"
                     /transl_table=11
                     /translation="MIDYSVFMMGNPMDVDAAQKAYAKAQVSEIMPFSQFVKHIADHNG
                     VFTRGTVKGVIADMCECLVEMLLEGKKVQLAELGNFWISIGSEGAEDLKKFTESNITAV
                     NIVFTPGEDFQNLRSRATFNPVASRIAQAATLKAEKAGKGTVDLDAAKGKTSASTNENN
                     PSL"
     CDS             25380..25748
                     /locus_tag="ctg68_44"
                     /transl_table=11
                     /translation="MGNASDRTMPKKAYAKCVANEKVSHKKLVKKVTEHLRFFSHGMME
                     AVLEEVFNRLSEHLAQGDRVTLDGLGTFSVSLKCEGAASEALFSKKNIKGAHIVFAPCR
                     KLKETFADMEYKMAPRIF"
     CDS             25792..25890
                     /locus_tag="ctg68_45"
                     /transl_table=11
                     /translation="MKKNWKNVLLYIVRIIELLITGAAGGALGSGL"
     CDS             25887..26306
                     /locus_tag="ctg68_46"
                     /transl_table=11
                     /translation="MRTVSLIIVHCSANKAGSALRAEDIDRYHRSLGWKCCGYHYVIPT
                     DGTIEAGRPPKMIGAHCKSHNSHSIGICYIGGLDADGKTPKDTRTEAQKVALRKLIEHL
                     HQRYPKALIVGHHDLNPQKTCPCFNVTAEYIDLQP"
     CDS             complement(26372..27202)
                     /locus_tag="ctg68_47"
                     /transl_table=11
                     /translation="MVTENSMELENQAFLSNQDITGEAPKLLLCSSIASGSDLGSNEGI
                     TPMAGIGKEYPEFSWYYLYLSNKELKRYISVFSGRKAVRLRTPSGTVEERFFCFKVFSY
                     TATDHRKRFEQCAYTKEEYTVRRDSARIVKEAFATGSIQKLNTLTDEKGIEGNGWLFVC
                     APLGQLECILSAMLPRQYLVTDYNTHRAAVIPHRQMEEFIYLYESMPYNIELMNRPLED
                     YLQKKQRIRITGGVFRGKEGCIMRLHRNTRLVFAFGNMTVAVSYLHAFPFEKID"
     CDS             complement(27626..29665)
                     /locus_tag="ctg68_48"
                     /transl_table=11
                     /translation="MKKLIYTLLLLLVTFPAMAQSLFEQYERFLTEPRTYVCYRPDGKL
                     KIDGKLNESSWNKAASTAPFVDISGEGFPTPKYETTAKMLWDDEFLYVGAVLQEEDIKA
                     RLTQRDTIIYYDNDFEVFIDPDSDGHNYFEIETNARGVIFDLMLDKPYRSGGNFMVQWD
                     CPGLKTAIHCEGTLNKSKDKDKYWSVEMAIPHQALTMNFNNPLKAGNTWRINFSRVQWL
                     KEKGPEENWVWTPTGRIDMHMPDRWGYLYFVDKKVGTSQDELVYPYNQAIYKLLWAMFY
                     AQQDNYSKQHNYLRATEQFFLTDKELKDLPADARIAVEATQNTYQIAITNPAEGIRYVI
                     NNEGRFRTEKIPAREVKNWLWMRLNNRSDAEWQKWFALLKECGISGVMFEGYNENIYRL
                     CKEAGLEAHYWKWTMNRRELLDKHPDWYAVNRKGESCHDKPAYVDYYRFLCPNHQGVAE
                     YLAEDYVKEAHKPYVDGVHLDYVRMPDVILPVSLWKNYGIEQKEELPEYDYCYCDVCRE
                     LFKAKTGQDPLELKYPMENQSWINFRLDAITRVVDAITKAVKADHKAISAAVFPGPSMA
                     RHMVRQDWGEWTLDAYYPMIYNKFYYEGPEWIGRSVKESVETVNGRAKIYAGLMFGDIK
                     DNFEEVLDEAYNNGASGVSFFDGPDEEYLHKFKAYLDKRGFVVK"
     CDS             complement(29684..31033)
                     /locus_tag="ctg68_49"
                     /transl_table=11
                     /translation="MKKNRLSLAFLGLLIAASPLRAQDTPQTETAEQKDKRMEWFSQAK
                     LGIFIHWGIYSVRGVSESWSFFNNYLPYDEYMEQEKGFTASKYDPKNWVDLIKESGAKY
                     TVITTKHHDGVALWDTKVGDISVVKSTPAKRDLIAPFVKEVRKQGLKLGFYYSLLDWSH
                     PDYPNKTRTEVRYKNDPERWARFNKFNFGQLAELNKTWKPDLYWFDGDWEQSSEAWNSK
                     GIVDLLRSDNKNVIINSRIQGYGDYATPEQGVPVVRPEDKYWELCMTMNDSWGYQHTDS
                     NYKSPYILLRTFVDCLSMGGNLLLDIGPKEDGSIPEEQIAVLKEFGRWTKKHKEAIYET
                     RAGIPTEHFQGYTTLNKAGDILYLYLPYKPNGPVEVKGLMNKVNRIWVVGNGAMLNYKV
                     YNKNYWNSVPGNLYIDVPQQVQDEQITVLAVLLDGPIKLYRGVGQVQDNN"
     CDS             31158..32015
                     /locus_tag="ctg68_50"
                     /transl_table=11
                     /translation="MSAKKKKQSNSSLRVIIILVLLGLLAYKHQLFDGKLLENIPTIES
                     NEEKPEILTSPQHGGALEIPTMQSGTGGQILKRKGYTLSYNADYKTPQWVAWELTKKET
                     KGKEGRTDKFLPDPDVRGAKAYTGDYTKSGYDRGHMAPAADMKWSKQAMKESFYMSNIC
                     PQNPNLNRGDWNDLEEKSRQWAKKYGAVYIACGPIYDTKRPKRIGNNKVAVPHAFYKVI
                     LINDKKNPQAIGFIFPNSAGHKPLKKYIVTVDSVEKRTNIDFFPALPDEVENRIEAERV
                     QELP"
ORIGIN
        1 gtaatggaag agtgatgagt tgttcgtaaa tctcgtccgt atgcttaaga gtcgtattat
       61 tttgattacc tgtaaacaat gtaagcaaat ggttggggcg ataatgtatg cctgttgcca
      121 ccccattgtc attcaaacat tgtttcacaa tatccctctt gccacaagtt attctaataa
      181 caaagatatg aggaaccact tcattataat tacagggtat aatttttatt ccctttacat
      241 tatcaagttc ttgctgataa atttttgcca gcctttgacg tatttcttta aacttaggaa
      301 atttcttcag ctgagtataa cctattgcgg ccatgatatt actcatatga taacgccacc
      361 ccggttgatt gacatcaaac acccatgttc ttgtaccctt gaatctacta tcggtatcat
      421 tctgtacact caaaaggcga gcatccttaa ttattttctg tacatcaagg tcctcagtaa
      481 ttatcatccc tccttcacca gatgttatat tcttgatacc atccatactt atacacacca
      541 catcaccaaa agatcctatt aaccgacctt tataataagt gccaaatgca tgtgatgcat
      601 cttctattac tcgtagatta tgcttttttg caaattcata tatagcatca agattaccac
      661 attgtccagc ataatgtaca ggcattatag ccttcgtttt tggagtcagt ttacgttcgg
      721 catcatccaa atcgatagta agcgtatcat catccacatc gcacgccaca ggtatcccac
      781 ctgtagctct tatagcttga aaacaagcca catatgtaag agactgtaca agtacttcat
      841 ctccatcttt tattcctaca ccttgtactg caagatgcaa agctgccgta ccagtattta
      901 caagtgtcac gtcacgccca aagaaatctt ttaaatcatc ttcaaattta tgtacatcct
      961 gtcccatacc caaatactct ctatgaagaa cgtctgttac ggcatctatt tcttccttac
     1021 caatgcaaga tttggacaat ctaatatttc tcataaacat catcatttta ttatcggtat
     1081 ttctctttcc cattttttcc atggagcaac tccatcaata agcaactgtt ccaatagatt
     1141 tttttcacgt atattatcca tacattgcca gaacccctta tgtgtataag acattagttc
     1201 accttcggta gccaacttat tcaatggttc tttttcaaat atggtttgat ctccttctat
     1261 ataatcgaac actctaggtt ccaacaccat atatccggca ttaataggta caccatcatt
     1321 gatattcttc tcacgaaatg aacgaatgga attattttca tcaatattta aaaccccctt
     1381 gtcttgtgct tgaataacag cagtaagagt tgctatttta ccatgctttt tatgaaatgc
     1441 cacaagctta ttgatgtcaa catcacacac accatcacca tatgtcatca taaaggtttc
     1501 attgttaaca tattccttta tacgtttgat acggcctccg gtcaatgtgt tatatcctgt
     1561 atcaactatc gttactttcc aaggttcaag atttgaatga tgtacagtta tttcattctt
     1621 accgttacgg aagttgaagc taacatcgga attgtaaaga aaatagtttg caaaccattc
     1681 cttaatatat tcctgtttgt atccagcaca aattatgaat tcattatatc cataatatgc
     1741 atattccttc attatatgcc aaagaatggg cataccgcaa atttcaatca tgggctttgg
     1801 cttaaattgg ctctcttcac taatacgcga gccaaaaccg cctgctaaaa gaactacctt
     1861 catatagatc tgctaatttt gttgaaatca aactttatat cactctcttc tattggaatg
     1921 tttacctgct ctagaggatc atgaggaata ttggctacat ttagaagaat gcttttacct
     1981 tcacctattc caacgaagcc catccatact ccagccggta ttgtgatcct tcgatacaat
     2041 tcaggtaatt caggtgacaa tatcacttcc atgtactttc caaatgtaga agagttctca
     2101 cgcccatcat ataaaacgaa atgtatcttt cctacaatac atactaggtt taatgtcatt
     2161 ctagaatgac gtttccatgc ctttaccaaa ccttgtaaaa cacttgagaa ataaacttca
     2221 ccaaatcctt caaatccagg gtcaacacat ttcattgcat gaaatacatc ccctttggga
     2281 tgagttatct gttttaaggg agtcagcaaa actccgtcaa ttgtgatatt gtccattatt
     2341 tccaattatt ttgcccaatc aagattctgt ttttttgcag cttccatata tgcattgatt
     2401 tgtttttctg tcaaagcaaa catatcctta gcctgctcta catagaatgc acgataccat
     2461 tcagcaataa aattcacaca ttcgtcataa tgcaaggttg aatgccaatg taaataagcc
     2521 aaggccttat cacagttcag cttaagcaat gtagcttcct caaaaggtac attgcctgtg
     2581 agttttgcag ctttgttctt atccaatccc cataaagtag caagatcttg aaacagttca
     2641 aatacggttt ttgtctgttc tgcacgtgga ccaaagttgt aagattcccc attttcgcat
     2701 ttgccttcac ataaatattg cgccaacgtc agatatccac ttaatggctc aagaacatgt
     2761 tgccaaggac gagtcgcctt tggacttctg atttctacag tctttccttc tgaaaaagct
     2821 ttcacacaat ctacaataat tctatctttt gcccaatcac cgccaccgat aacgttacca
     2881 gctctagcca caccaaactt aatgtttggc attttcttga taaatgaatg ccaataactc
     2941 ttaatgacaa gttcggcagc acctttagat ccagaatata tatccttacc tccaatacca
     3001 tctgtttcac gataccccca aatccactct acattatcat acgctttatc agaagtaatt
     3061 agaacacaag tacaattcca atcaatgttc atgacagctt cacatacaac agctgtaccc
     3121 acaatgttag tagtcattgt ttcaaatggt tcgcgataac ttgtcaagac caaagcttgt
     3181 gcggcaagat gaatcaaaaa atcaggtttc acttcctgca caaaatcatt aaattccctt
     3241 ttgtttctaa tatcaccata gtgttgacat atcttatctt caagatgaag tgtatcaaac
     3301 atcgatggag ttgtcggcac accaatcgaa tatccataaa cctcagctcc catcatttta
     3361 agccatgtag acagccaagt ccctttaaac ccagtattac cagtaataat aaccttctta
     3421 ttcttataaa tattactaaa tgccataact atatgttttt tttatattcc gcaaaaagat
     3481 attttgttgt tttgaatcta taataaccgg tagattcata atcgattttc ctattttttc
     3541 cgcaactggg catcctcccc aatgatatcc aaagtcacat atattttctt ttgttgcaac
     3601 aatcggagtt ttaaaccaaa tccaatcatc aatgtatgag aatacagtaa gagcgaaata
     3661 agttgaataa gcaatacgca aaggaataat gtcacaacca gtatcataat aagctgcagg
     3721 catatcttct tttttttcta caacctgtaa aatttcttta agccaactct gcctttgatg
     3781 aatattagct ttatattgtt caagaacatg taatccaatc tttgccaaaa cagaaggtag
     3841 tttagcagga taactgtaat aagggtttat tgcgattttg gcagatgttt ccaactccaa
     3901 ataaggagat atttcattat gaatatgtag cttattcatc aaagcctttt tatagttccg
     3961 cattatgtat attttatgat ttacagtttc tatgcggtgt tcatcaatat aagtctttaa
     4021 gatcattcgc tgatgttcgt tgcttaaatc cccacaatca tcacgcattg cccgaataga
     4081 tgtagctatg tctatatcat tagtataaac aaagcctcct ataagtgtat taagaggttt
     4141 ggtatgatct gttgaaaata ttgcagcatc accataattg ccaactataa tacttttata
     4201 ttttgaacca aaggtcaacg cacaatcttc cactaaatag caactatgag atttagcaat
     4261 ctcctttatt ttatcaatct tacatggaat tccaaaagaa tgctgagcca caactacttt
     4321 tgtccgattc gtaattttgg acactaaaga ttctgcagac attcctaagg tatccttgtc
     4381 gatatccaca taaattggag ttgctccagt tcgcaaaaca gcattagcca taacagcaca
     4441 agtaaatcct gtaagagcaa cttcatcgcc ttctcttatt ccccagcttt ttaataaaga
     4501 atagaatgac atacgtcctg atgcgaaagt cacgacatgc cctcctccaa gaaattggct
     4561 tagttctttt tcatagcgat taacataatc aagattagga gcctctatca gtgcttcata
     4621 gtctgactgt ttttctgata tatcaatact tggagaaata aagctactga tttcagacgt
     4681 aaacaatagt ctaaacattt ttttcatttt tgatattatc ataatctcta aatggtttcg
     4741 ttttccataa ttcctttcta ttcaacgtct aataattgac ttcaccaatg aatacatttc
     4801 tctattacaa cacactgata ctagaattga tattaaaaca atcaatccca taaccaataa
     4861 attataacaa agggaaatct tattatattc ataagccata taaggcttta caagagtact
     4921 taatactaat agtacaatta aaggtaaaaa caaagttttc aaaattagga atagtgaaac
     4981 tatctgacca gcattctttg caaaatctct gtataatgaa taccaataaa gaatacccaa
     5041 aaatatagga atcagtcctt tagatatagc gaacgaaaat acgccccatt tatcaatagt
     5101 aaaaaaaatc aacaaccagt atagtatagg ttgaaatata ttaaacctat taagtaaagt
     5161 agttttttca attgcaataa aataagaaga actagggttt gagagaaagc aaggaaagaa
     5221 acaaaacacc aaaagtgata aaatagaact ggattcctca taattgaatc caacccaact
     5281 tataataaat ggttcactca gcatagacaa tccaacaatg ggcagaacta ccattggcga
     5341 gagcattaat aacatccgat tcacaaattt catcagtccc accctgtcat tttcaccaat
     5401 caaatgatta tatcgcgatg aataaggtga ataaagtaat gacacaaagg ttcgtacaaa
     5461 ggtcaatgca gaaaaagcta tgccataaac tgctactgcc tccagaccaa caaaatttga
     5521 aatcgcgatt tgatcaaatt catagaacaa cacccaagaa agtatagata taaatgaagc
     5581 tcccgtcaag cccttttctt tatcaaatat aatacggtca aaacggatag ctttaagaaa
     5641 ttccacaaat gaatattgat actttcggac ctgaaaagct gccatcaata ctacggatag
     5701 gttgataaac tgcacgaatg caaaataagg taccaacaaa taattttcac ttccaaaaaa
     5761 aaagaaaact gataaaatct tcagaatact gcctaccgca gagatacgct gtaatttata
     5821 atcttccaca cgtatggaat aaatcatatt aagaattcgt tggccaatga ttaccggaca
     5881 ggaaacagac aacagaatca gcaaataacg tgccgtataa aaattttcac gatccggttc
     5941 caattcaggc atgagaattt gagggaatat gctgattatt ccaaatagca aagctatcag
     6001 cataaacatg ctaagcataa taaatgcagt aaaacctatc gtacgaattt cattctttcg
     6061 gtcaccacga atataatatt ccgctgcata tttcaatccc gatgaaataa aacctaaatc
     6121 agcatacgaa aagaatatag tcagagacgt acaaacactg taaataccaa agagtgtttt
     6181 atttccagaa agtaaaggca tcacaataaa aagcgaaaga aaacctaaaa ttatggataa
     6241 tccttgccaa atgtaaatcc taaaatattt tccgcgatat gatatactca taggtatcaa
     6301 gtgaaaagtt ggaaaattaa ctgaggctct agtttggtaa agaaatagtt tctcaaccga
     6361 tagccctcgg tcattgcatc ctcaatattt agattcaata tcctaacaat agcatccgaa
     6421 agttcagcca aattattggc agtataccac aatacttcat tcacctcttc tattttatca
     6481 aaaagaatga tggaaagcgg atctttcaga ttaataacag ggattcccaa acttaaggct
     6541 tcaaacatca cagatgtgtt agctgcaaga attgcgtctg ctttcagcaa gaaagagttt
     6601 acattacctt ttactacttc tagctttccc cctgccttgt ttgtacagga aaccatccat
     6661 gatgaatttg catcaggatg gggcttcaaa agtatattaa tattagcatt agaagattta
     6721 ataaaatcag tgagcaattc gtatttatac tccatatcat aattatcgag tgcaaatggc
     6781 accaagagcg tgaacttatc atgaggtttg gtgcttctat gactgctata tatctcttga
     6841 tttctcagtg caggagctat atgcttatac ccgttataat tttgatagaa ctttagcaga
     6901 taactgctac ataaataaat atcttttgga gcaatatgac aaaataattc tttattcgat
     6961 gctataatat gtggaaaaat tgttgaatca gcaataaatc ccatatatcc atgaactttt
     7021 gcctctggat agtattgatg cattgcgtaa tatactgatt tgtcgtagct ttggttctca
     7081 aaccaatcca caaataagca aatgtcaaca tccaattctt tcattctcat aatagctctt
     7141 tccatcaaaa tggcatagta gaaataactc tgattactct ctttgtatgc ctttcccaaa
     7201 agccattgaa gactgaatcc ctgataagta taacttgcaa aatctggctt ttcaaaacgc
     7261 cccatatagc gccatgcgta gagataatct ttaaaaagta aaaaatcact cataaagaac
     7321 aagttttcct tagaattggc aacaataata tccaattgct tttttgaggc aaagggcaaa
     7381 tacaaaggca tgaaatatat ttgttctttt tgggcatcaa tcaatttatc tacagaattt
     7441 ccataaaaac gatcccaata ggcatcaacc ttttttgcaa taaaggtatc aatgatagtt
     7501 aatcttcccc ctcggcacac cttattacgc ctctctttcg aaccgctaag ccatgaacag
     7561 agtgaccata ttccatatcg aatattattt ttccataaac gaatattatt tttcaaagaa
     7621 cttgtcttac catgcacatt tatcttagga tacagatttg aaatggtttt tcgcaactca
     7681 tcattatcca ctatgatttc ttctattatt tctccgctac ttataagctc tgatatcaat
     7741 cgcaaggact caagttctgc cagcattgaa gaaaaaacgg tactacgaga atttacgtta
     7801 caaaccagcc attccaaact atcacgatta taatcaatta actgttcggt caatgcatta
     7861 tagtcggcaa tcacattttt tttcagcttt gcctttaatt tactctgttc cagagttagt
     7921 tcatttagat ttaatatcat ctattttatc tttaataaag cttcactcaa taaatctgca
     7981 cttgcttttc caatctcatc ttttgtataa agatatttat caataaattc atcgtacacg
     8041 ctatcaaaca ccacagggac ggatatatca gcatcttctg catcaatatt taccaatgga
     8101 ctttggaaaa aaccagagta actcaactca gctgcaatgc catacttgtt aacgacttca
     8161 tcagtcgtga taaacttgat tggtttgtgc tgtattataa gaaaagtaat agctgtactc
     8221 aaatgattaa tagcccatgc acaaccctta cacaactccg cagtctttcc aaataatacg
     8281 ggtctgccgt caaaatagtt atgttcatga tatttttgag cactaggatg tgcagctata
     8341 actacaggta acccatactt atcctccaca cgtttcaggt aattatttac tgatttaaaa
     8401 tattgttcag gatcaatatg tccactggca gttacttcaa aatcaggatg gaaaggcata
     8461 taagcatcaa taaacacaat atatttccta tcattatacc tttccatttt atccacctta
     8521 ttaaaatgct ctatatcata gtctacaatt gttattttct gcgtcttgtc ggaaataagt
     8581 tgagatgcag agttaatact gtgtacacct tgagtcacag cataatcaaa atcttttaaa
     8641 taaccaattt ttctcaatag aggaatagac ctatgaatga aataatacct cactctaatc
     8701 gggttaaaca aaagtttaag tctatgctcc attctatttt tggggagagg caaatgcata
     8761 cttccaatat tgaaatagcc aacatttttt tgttttgctt tgcttaaaat tctaaacaac
     8821 ttcaaacaag gagcaaatac aggcattaat gaaatgagaa tagcatcttt attgcgatct
     8881 agatttataa tccgctgaat ttctttccaa gatttgggta tagtttcaca acctttggaa
     8941 gatacattac ttaataaacc aactaacggt ccaatccaaa catactcaat tgggaatccc
     9001 ttttcttgca attgttttaa cagaaaccta tcattataga cttctttcca aggttcaata
     9061 ttaaaaaaaa acagttttgg cagattttga tttgacatcc ttatttttta ttataattat
     9121 ctctaatatt taaagtatta accacttttt ctgtttcaaa aaataccata tttgtcctaa
     9181 atatcaaaat tctctttcac aatcattggc tttatattat acccataaat atccatagtt
     9241 gctacccttc aaactcaaaa tatagagaat tctttaaact cattttcacc agtcaagtat
     9301 acttccccat aatccttatc cagcctttat gttaaagcgg tatttaacac cggggtataa
     9361 aaactcccca ccatattttt ccccttccag ttccacatcc aatccttgtt ccagtgccag
     9421 attcataccc ggaagaatat cccaagaata acatcctttc agatgtaaaa actgtctgta
     9481 acagcctcgt ataacattat acatattata catgcaacac cccataatac gatattcaga
     9541 gccctgttcc aacctcttaa aatcttcagg ttgcatataa gatgacagcc cacaaattct
     9601 tgaaccaata attttagaaa actgatcacc tgtacataaa cgaattccca attcgggtaa
     9661 cataatcata ctttgataat gcctcattcc tttataaaca gaaatgccga ctccccattc
     9721 cttcagacct gaaacaaaat tctccgtacc gtctatcggg tctaccgtta tcacatactc
     9781 aacttcttcc aaacgtgaca aattcgtttc tgtttcctct gaaataacca aataatcctt
     9841 cagattggag tccaagaaat caaaaatgag tttttcacac aatttgtccc ctttggaaac
     9901 aaaggtatga tcggatttca actctgaagt attccgtaag gagagaattt caggcaaatg
     9961 aagcataatc agttcatgta tgcttctaca aatatccggt tcattcatat agagacggag
    10021 ttaaaaattc aatatccata acctttccta tttcactgat gcgatgcttt atcgctttat
    10081 tcatttccaa gacataatcc ctatcctgaa tcagattcaa acgctcctga tagtagtttc
    10141 cctttttcat agagtaaccg tccatacctg ccagataaac ttttcgagga gacagtttct
    10201 gtaaaaggtt caaagccatc agagccgaat tatcacgaat aatgtccact tcgttcagca
    10261 aagaaacata attgacacaa tagccagatt gttcttgatt tgcacgaata ttggacgtat
    10321 aaatcaaact cacctccttt ttcatcggat taaaagtcgt agcataccgc ttggcattag
    10381 ccaagaaagt aaagtcacaa tccataaaat caggaacaaa ggtcacagaa ataagcagac
    10441 agttctccga attctgtttc tggacaattt cgtcataaca gtctgtaatt gaacctcctg
    10501 gagccatcag tataatattt cttccaccta ttttttcttt caagttcttt aagacataag
    10561 tatcatccac ctcatgagat tgatactcca aataaatcct atttaccaat tccttattgt
    10621 ataaagaacg cttttcgaca ggaatcatat gcaatatggc agaaatttcc ttcacagcaa
    10681 gcgtctgttt ctgagccaga taagaggcat aattaggatg gcaaccatta atagccgcca
    10741 aataataagg aacagtatac ccccactcat gtttctgcct aatatgaatg atgaattcat
    10801 caacaacctc caacaatggc tctatagcat acatatgccc ttcacggtca ttaacataat
    10861 tggcaatcag ttccgtattc aggtttccgg cccctcgtcc cattccatag atagaagcat
    10921 ccaacgaaat gacacggtcg cctacatatt caaaaaactc ctgagagttg gaaaaggaaa
    10981 gctgtaagtt attgtgggaa tgaaaaccca tatttattga cttgtccaga ttagtattga
    11041 tcagataaaa aaatctggct atatcattct tgtgcatcag tcccaaagtg tctaccagat
    11101 aaaaggaata gggttgcaac tcattcacct tctctatcag atggagaagc tggatatcag
    11161 tataactgga cgtgcctacc ggttgcacaa aaaccttata gcctttttct tttatttccc
    11221 gacagtattc caaagcaccc tccacttcat cataatgaaa agtgacccgt attccatcta
    11281 tggaatttct agtacaagga ctcagctgac tcagatcgta ttcaccataa cagaccatcg
    11341 ctacaaacat ggtacgtcca tgttcattag gtaacaggga ggctatctgc tctgcggcat
    11401 taaaaatgga ggtatcctcg tcgtattcac catcctccaa aaatccacat tccactatat
    11461 ccaaacctgc atgggtcagt tgttgaagaa ttttccgtat ggcatattta ccgaatcgga
    11521 aattattgat gtaccctcca tcacgcaaag tacaatctaa tagttggatt ttgctcataa
    11581 tacgatctcc ttatttttaa tcctgcgctc taagacttct gtcacaattt tcacatcagc
    11641 ctgcgtatct acagataaag tttcagctgg aatctctaca aactttattt tttttccgtt
    11701 ttccaaaaaa cgatattcgt caatatcctc tatactttca atttttccgc gtttattatc
    11761 cttgcagaaa agcaaggcag aacgtgagaa acattgtatt ccaacaaatt tcatatagtc
    11821 aaaatccgag ctggcctttg gatatggaat aggagtccta gccatataca ttgcatatcc
    11881 taaattatcc gttaccacct ttatacgaga aatgtccgcc acctccactg tcttttttat
    11941 tttagtcata gcattagcaa aataaaaatc agcaggattc aagtcggaag taggtaaaag
    12001 tcgttctaca tattcgggca tcatcaaagg ttcatcacca ttaatattaa tataaaaatc
    12061 agactctata ttttcggcga attcagccaa gcgatcaaga tgcgtgggat gactatctga
    12121 agtcatcaca tatttaattc cataatccga acagaccttt ccaatacgtt catcatccgt
    12181 tgccacataa atttcactca atccttttac ttgacaaagc tgatgatgaa cccaccaaat
    12241 cataggttta ccacaaaggt ttactaacgg tttaccttca aaacgcgtag acttatagcg
    12301 cgcaggaatt actgctatta ctttcattgt atgttgtatt ttaaatttat ttcaaatgtt
    12361 tcaccatctc tctagccctc gccaattcat catgctggcc aatatccagc caatatccac
    12421 taataggata gcgaatcacc ttgtatccct gttcaatgag tttatccatg aagtcagtgg
    12481 cattaaagaa gatatcatca ggaataaggt caaacagttt gcgtttgata aggtatatac
    12541 cggcgtttgc ataataactg atggtgggtt tctcggtaac gcccttgatt tctcgtcctt
    12601 cgagattgaa cacaccgtat ggcaccttca ctacgtaggg cacagctgcc acactcatgt
    12661 cagcatcatg ctgacagaaa tgaaggaaaa agtcctcaaa atcaatattc gtaaaaaggt
    12721 ctgagttcat taccagcacc gtatcattgt aaaaagtttc cacgaacttg atactgccaa
    12781 tggtacctag atatttcggt tcacgcacag taactatctt caccccatcg cgttcctccc
    12841 ggaaatgttc ctcaatctgg ttgccaagat agttaaccgt tacagatata tgattcaaac
    12901 cgtatgaaag caaacgatca atattataat caatgataca cttgtcacct accttaatta
    12961 ggggcttagg agttttctcc gttaacgggc gaaggcgctc ccccttacca cctgccatca
    13021 gtacagcatc aataggtagt ttggttatat aatgttccaa attgatgatt tcgcaaatat
    13081 gattctcttc atcaagtacg ggtactaaac gcatctttaa atcacgttgg cggtgaatat
    13141 cctccacacc atcgttcact ccgcgacgta aaaagttaaa attacgatgc atggcctcac
    13201 taataggagc atccacatct atacctttaa tcaaggcacg acgcacatca ccatcggtaa
    13261 gggtaccttg catccttttt tcagcatcta ccacaaaaag cactaacggt tcaccatgaa
    13321 tctcgttgat gcaacggatg gaatcaatga tggaaaggga ttgggagatg atatgggaat
    13381 gattcatctt atttcaatta tattagatgg ttatttatca tgtattcagc tatctgccaa
    13441 tctatcattg tatcaagatc aatagaatgc cctcgatcca tcacatactt gacacgttta
    13501 gtgaatttat aaagtggcat ccgcttcaag ctatcgggat taatgatata aattgcacca
    13561 ttgtattcgt aaaccggtgg acaatcttga cgacgggtat aatgtccatc cccttttgaa
    13621 atgtgcaaca ttccattggc atcgtcctcg aaacaaatat aatatggatt agaatccgtt
    13681 tctttcacac tgactaccat atcaatctct ttggaataca acttaagtgc ttcctttatg
    13741 tgattacccg tccgaaaagg agatgtggcc tgaagcagca caaccacatc aaaagtttct
    13801 ccttttgatt cataataatt caaagcatga agaagaactt cgtatgttcc cgcagtatcc
    13861 gtagcaagtt cttccggtcg tttaaatggc actttcaatc catattgttc aactacttga
    13921 attattctgt catcatcagt ggatacacaa atatgatcat tatcggtgac tgctcttgca
    13981 gcatcaatag tatatccaat caaaggcttg ccaccaagta tcttaatatt cttaccagga
    14041 atgcctttac ttccccctcg gacaggaatg ataaccaata tattcatact tctatagatt
    14101 ataaaatgat ttccgtttca gttcatcaag cggatatgta gaaattacat cgaaaacaga
    14161 ttgtaccgta ttctcttttt cgtagggatt ggaagctttc aatgcgactt ccttaaatga
    14221 taaagaaagc accatggtaa gcccccttat aatagattct ttatcacttg cacaatcgag
    14281 caccgaattt ccgtgaacgc gtcctttttg acgatcccca atattgagtg tcggaatatg
    14341 aacggaaggt acttcaagca acccactgga ggaattgcct actacagccg ttacatactg
    14401 taaagctgaa agataacgtt tcagacctaa cgaactgtaa caactgcaac ggtcactatt
    14461 ccgactgcaa tagccctcaa tagcctggcg tatcacttca ctgccctcat ctgaattagg
    14521 catggtgaaa agcaccttca gtccggggaa agtatccaac gcaaacagaa aatcatcgat
    14581 ctcatccttc ggactacgat tgcccaaagt gaccggatga taggttacta aaatgatttt
    14641 tctatcgaaa gtgaagttta atgaatcttc caagtcttgt ctgctcatca aaggtatttg
    14701 cttcaagttt tccactccaa tggctccaac atagaatact ctatccggct gttcacctaa
    14761 ttggattaca cgacgacgat aatcttcagt ggatgtaaaa tgaagagaac tcatttttgt
    14821 aatggcatgg cgaatgctat cgtctacggc tccttcactg atttccccgc catgaagatg
    14881 tgctatggga atccgttgca acatggcaac ggtagccgtc accaacattt catatctgtc
    14941 tcccaagatt accaccatat cgggatggag ccggagaagt gcttcattca tacctttcat
    15001 ctcttctgcc atggaatcaa tcaccccata agagtcatcg gacagctttc tcatgggcac
    15061 tttagcatca atatgaaaac cgtcacattc tatctcctga taggtatttc catattcagg
    15121 aagcaaatgc atattggtag caatgacttg aagctgacaa tctgctgatt catcgattag
    15181 acgcatcaac ctgctgagta atccgtactc ggcacgagtg ccggtaacta cacaaatttt
    15241 tctcatatct ctatcaattc atcttcattg aagtcacgaa cagctctctt gcctattatt
    15301 tcgggccacc gcataggatt tataccgttg cctggacgtt tcaccgtaag gttctcttcg
    15361 gtgaacaact cacctttctt aatgtcccga gcagccacga tactcttgcg tgcaacggct
    15421 ttgttcttac gttcggaagc ggagacggtt ttgtatccca tgccgatagc ttgttcaata
    15481 ttacgaatgg cagttaccat ggcttttaat tcatcaggtt ctaatgatgc tttatggtcc
    15541 ggaccgggaa gggaacggtc gagcgtaaaa tgcttctcta taatctcagc tcccatagcg
    15601 acagcggcaa tgggcacttc aataccttgt gtatggtcag aatagcctac cgatacgccg
    15661 aactgagaac gcatctcatt catggcggag agattgacat catacatcgg ggtgggatac
    15721 tcagtgttgc aatggagcaa agttatctgc tctttctgca agccatgggc tgtcaataca
    15781 tcaaaagcag attgaatctc ctccatctcg cacatacctg ttgacatgat gacaggaaag
    15841 ccagtctgag ctatttttac cagataagga taattggtaa cttcgcctga agggattttc
    15901 caaaagccca aattcaagga tgccagatag tcaatactct caaaatcgaa agcagtggag
    15961 agaaatttca cgcctttctc acggcaataa gttaaaagtt ccacatgctg ttcgtgcgaa
    16021 agctcaagct ttttgagcat attgtattga gaggtattgc catcaccaat attatgttgc
    16081 tgatactcgg cttgttttgc ggattttgta accagattct cagccttgaa actctgaaac
    16141 tttacatagt caacacctgc ctcagctgca acttttataa gctttttggc tatggtcaga
    16201 gaaccgttgt gattaactcc ggcttcagca ataataagcg tatgtttcat tattgattcg
    16261 tttgtagtct gtctcccact ttcaacttac attccgattc gtattgcaca attttaatgt
    16321 aggaatcttt tgtttttaca atagggcaag catgctccaa tccgatgact tgtcccggaa
    16381 tacctttata ttgcggataa ttttcattat attccacctg attgataagt acaggaatgc
    16441 ccttgcagaa agtggttgcc atcggaccag gctggcagat agagcgaaca aagttaaaca
    16501 attcccgtga agtcatctgc caatcaatca actcatcccc tatttgccgc attccacaat
    16561 aaagtccatg atgagaaatc atgtcttgcg gcacgcgctt ggctttacct gcttgaatgt
    16621 ctttaatggc ttgataaaga atcttgggac acgcttcgta agcgacttga agcaaggtat
    16681 tgtaactgtc tgcatctgta atgggaaagg ttcgttgcag gatgatgtcg cctgtatcta
    16741 tgccttcgtc tacatagtgt acagtgatac cgaattcttt ttcatcattg ataagtaccc
    16801 aattcaagat gttacgacca cggtagaaag gcaattttcc ggcatggcag ttgatcgttt
    16861 tacatggagg caaatcgaat attttgcgtt tgaagatttg gttgtaactc atagatacaa
    16921 acaaatcgca accataattt atagccttct gataaaactc ttctgagttt accttaaccg
    16981 gcatcaagta atcaatgcca tattctaagg ctttattctt cagatactca tctttggtat
    17041 cattacgagg aacaataaaa acaatttcta aagtttcatc cttcagtaaa gtgtctaaag
    17101 taaaatgtcc ccaaagacca tcggcaaaat aaccaattct aaatttcttc atttttgtat
    17161 agtaattaat taagctgctt tctcgcagga aagagtattc atactgctac aatacatact
    17221 atcattgtct gtaccgataa tggtataacc caaaacttct tcaccaacct gtgaaggaat
    17281 atctaaaatt ctctttataa ggtatcctgc actttcggca gcctctatca ctgacttaca
    17341 atgaccgcca ccaccgacta aaatcaaagg tcgtttcatt attctgttac aatcttacag
    17401 aactgggaat attcaccacc cggtcagcca gccactcagt gttctcaagc ccgtccgtct
    17461 cgcaatgctc gaacatgggc agacggttca tcaattccca aactggacga gtcatcacac
    17521 cgtgatcatt tgtatattcc aaaaattcaa gttgagcaac cttatccttt agtaccaccg
    17581 cattgagcca ataattcgat ttgcaatcag caggttcagt aaagaaagta atatcttcct
    17641 tacccttgaa aaactcaaca taacgagcgg ctgtctcacg cttatctgcc acatagcggt
    17701 ctagattctc caactgggca caacctagag cggcattgat attcggcatc cggtaattat
    17761 aaccaatatg gtcatgacga aactcccaac gatgaggtat cttagcctgg gtagtaaggt
    17821 gcttggcgta tgcgcccagt tcttcatcct ggaaaagcaa catgcctcca ccacctgtag
    17881 tgatggtttt gtttccatta aagctaatag cacccacctt tccgaatgta ccggtatggc
    17941 ggcctttata aaaactgccg atactttcgg ctgcgtcttc aaccaattcg atatgccact
    18001 cacggcagat atccgccagt tcatctattt ttacgggatg gccgaaagtg tgcatgggaa
    18061 tacaagcttt tacacggcga ccggtacgct tgttatagca aactccttct ttcagttcag
    18121 cattcctctc cagccatgcc ttgacagctc ggggcgaaag tcccatcgtt tctttgtcca
    18181 catcaataaa aacaggatat gctccgatat aactgacagc attgcaagta gcgatgaagg
    18241 tcagagcttg ggtgagcacc tcatcatcgc gttctacacc cactagcagc atggccatgt
    18301 gaagggcatt ggtaccactc acacagacta cggcacgctt ggcaccggtg tacacagcca
    18361 tatcgtgctc aaagcggtca acaaaagcac cgacacttga cacgaaagtc gtatcaatac
    18421 attcgttgag gtattttttc tcgtttccga taaacttggg agcactcagg ggaacaaaat
    18481 cttgtgttcc aaaaagatgg tgaatgaatt cacagatttc agcgttgttc attgctgtat
    18541 gttgaattat tatttaatac cactgattga caggcgcatt ggcatcttta ggcaaatcat
    18601 tagtgtccaa ccggggaaga ttaaatatag catcgccttc atggtcagta aggtctgcca
    18661 aatccacatc ggtagtcatg cccaatttgc atccgttttc cttcagcagc tgaatggttt
    18721 ctttattacg gtcaccgtat ggataacaga tagtccaatt gtcgacatcc ccacccactt
    18781 catttataaa ttcgatggac ttcttaattt caaattcctg tttctcacgt ggcaatgagc
    18841 ctagccaata atggtcataa ccatggctgc caatgtgcat gccacaatca accatacact
    18901 tgatttggtc aaccgacata taaagttccc tgctaaaggc agattcctca atacctacaa
    18961 ttttctcaaa cagaatatca gccatcctct ttcttaatgc ttcaggcaaa gccacttgaa
    19021 gcagccgttt tacgaagata acctcggcag gatcgaaacg gttagccact gccagttcct
    19081 tgaaatattc atcgtatgat tttaacccga actcatccgt attggccaga atgagctgtt
    19141 ttatctcatt caataaaacg ggaaaattat cttcgggtgt agaggcaaga ataaaatgta
    19201 tcttatttac atccagtacc gtatgctctg taactgcctt cactggagga tagaaggcac
    19261 cttgaatatg ctcatgctcc aaaatcggga aaacatattc aaaatggtcg gcataagcat
    19321 catcgaaaga gagaagcacg gcatgaggtg gcaatttgtc actatgcccc cccctatatg
    19381 catttataac ctgttcaata gtgacaaaat tatagtgttt ctgcagaaat ttgatctgtt
    19441 ccttaaaaag tcgcacatcg catcctttta tttggggata gcgtgaattt tgcaaatcgc
    19501 gcacatagtg gtacatgacc acggtaagtt tatcagcatt cataatagta tgaattaaaa
    19561 ttagagtatg ttggggcggt cctgatcgga atccgcttta aatgcgacat aattatcacc
    19621 ctttgtctta tatgctattt caatcttcac attacgctgt tcaaaaggtt caaaatagtt
    19681 ggggacgatt gtctcaccat ccaaatccaa cagctcaaat cccatttttg taaaggtctc
    19741 ttcaggcagc ccaaaattca taaaatccat atattccgct cccgtctgat aaagtatatc
    19801 gagtagctgt cccttgacac atgtattggg aagtttaccc aatacatcaa caattctaaa
    19861 ggctgatgaa tcgcccactc tcataatccg cactgtccaa acggattcca atattccatt
    19921 cttctttacc tcgacaaact gataatggta aacaggatgt tccgcaaagc gatggcaaaa
    19981 atacaaaggg gtcttgaagg gagcgtattc tccttttata gctattttat cccattctac
    20041 attatggacc aattgcaggg tatacgattc atcggaaatg gcagaaccat tctggcttcc
    20101 tacaggaaag aaggctattt gataattctt tatgcggctg ttgcgaaggt aatattgacg
    20161 aaggtagtca accggtatgc gggagacttt ataaatctgc ctggcaatgt cacttatacc
    20221 tatagccgca taggagtgaa aatatggtaa tttgaagagg ctgcgccaca aaaagaaagc
    20281 taccgtgttt aactccgagt tataaatatc atctcgtatt ttccatatcg ctccccaata
    20341 atcgccattt ccaaccaaat ccttatcata ttgcgcaacc ggaatgaaac ctatcaaagc
    20401 atcatattca ccggtctctt tattttccgc aacaaggaaa ttgtaacaat ccttatcttt
    20461 gtccagatgc tggaaattga gtaattcccg ggatacggca agcgaatgat tgtgtttcca
    20521 atgcatattg ataaaatgaa ccaacttatt gacttcacaa gttggaactt gctttatatt
    20581 ataaacactc tccatacata ttcttcttaa accgttccgt tatctacatg aatgttttgt
    20641 cctgtaatgc tacatgccga gtctgacaac aagaaaacga cagtctcagc aactgaacgg
    20701 accgatgtgg cagcctttaa cgaggtgcgt ttataaatac gttctttctg ttcctcagaa
    20761 agagtggaac tcatagccgt ctccatgaaa cccggtacca caacattgct acggatacca
    20821 agaccacccc attcacgggc cgtattctta gaaaaagctt ccaaggttcc tttgctggaa
    20881 gcatacatgg ccagtccttt gtaacctgta tgagcagaaa tggaagatat gtgaataata
    20941 caacctttgg tatgatgaag caacatatta cgaagtgcat acttggttat catcatcggt
    21001 gtaaatacat tgaccgcata catggcttgc agcttttcca aattgaggtt ggtcacaata
    21061 tcgtcataag ccatggccgc attgttcaca tatccatgaa gctggatgcc gttgtgtata
    21121 aattctctaa aaactgtctt gcgtacattt tcactatcac ttaagtcgat acttttgaaa
    21181 aatacacgtc cggcatattc ggtttccaaa aatttaaact cattggtgta agagcgggct
    21241 actccataga caatatgccc ttgttgtaaa agcgcccggc agatttcaag acccactcca
    21301 cgtgagcacc cggttactaa gaaattcata atcgttttaa tttacctgtt cttgttaacg
    21361 agaaggattc gacgaatctg atgcgacggg ggattttaaa atcctgaaga ctgtctttca
    21421 ggatacggcg aatttcaagt tctgaaagcc gtactccttc ttcaagttgc acctccgcac
    21481 aaagtatatt gcccaaaact gaattggctt tgccgaatac caaagactga cgaatgcctt
    21541 ttatggcatt gagcacattc tcaacttcgc ccggattcac tttatatccc ccaacattga
    21601 tcagctcatt ttttctactt ttgaatttga acactccctc ttcgcgattt atccattcta
    21661 tcaaatcacc ggaatgataa taatcaccat caaacctgaa actgtcggat tgtcctaaca
    21721 gagagcgatg aatcaggagt tcgtcatcga ctacctggaa catatcatga atcgatgcag
    21781 gaatctgaaa gttttctcct ttggccgcaa acaaggaccc cgcttctgta gaagcataga
    21841 cattgtttat ttgagctgac gggaatatct gacggatgac attataaaga tgtccatcac
    21901 tcttttcccc ccccaacgtc agacggataa ccgaagaata agctctttca tagggcaata
    21961 atagacgata gaaagtagga gtggcggaaa tatgggttat agagtgtttt tttatcagat
    22021 tgaagatttc ggaacgggta cgattaaata cattaattaa tgtattgaga ttttcaaatg
    22081 cctggaaaaa cacttgcaaa cctgccatat gcgtaggatt gtaagcatac gcccaaattt
    22141 gattgttgta cttttctccc cggcgcacag agcgagttaa agtctgtatg ctgtgcacta
    22201 cctttttggg ttgaccggta gtgcctgaag taaacatggt tatttcagaa gttgaatgta
    22261 ctagcgcttc tatcacttct cccatggatg gcaaccgctt cacagaaagg gggatagact
    22321 gattgaccag gctttcatcc acaccatcaa gttccgcagg gctaagatct gaatcgagca
    22381 agacaagcgg aacgtcgttt gtcaatgcct tgaccaaatt gccaaaatag gaaaaaaggt
    22441 gatgcgtctt taataaagga aaatagttgt cctgattcag gtgacggagc aagtcatcat
    22501 aagagtactc acattcgcca tcgcataaaa atacagtcat attatatctt acttttgaag
    22561 ttttgagtaa acttcaccga tagtatttac caaaccatcc tcaaaaatat caatgtcaaa
    22621 ttcatcctca attcgaactg tcagttctgc cagatcgaat gatgtgaatt ccaagtcatc
    22681 acgaagattg tcttcggcat gaagttgggt tatggcagac aattcttttg ccaccctgat
    22741 ttcatttact atttccaata ctttttcttt catatcattc actcgtttaa attacatttt
    22801 ctggtccaga ttcttcccct tttcctcatg ttcaaagttg gggatgaaac gctttatcgc
    22861 cataaccacc tcttccttgg taaaatccgg ttcggcaaat atattctcca tttcagtaaa
    22921 gaatgcgtct atctcagcca tcggccgttt caccacttcc tcaatcaccc ctaggctgca
    22981 aaaacgatcc atattaattt tttccccagg aacatagaac tcctcgtagg ctttctctcc
    23041 tgtcgtgtca cttttaaaat acaccacagg ataatcctta ttgttaaatg ccatttccga
    23101 agcaaatttc ttcgcttcct catccgttgc aaactctttc ttctcgcagc caaccgcttt
    23161 tatatactca tcacaaatgg aagagaaagt gagcatctgt ctttcaccca actttgggaa
    23221 gaatatttca ccattcttac ctagtatgca ggcaagcata catatctggc cgctttcctc
    23281 cggagagaca aagtagcgtt tcacatcatt gggtgcagcc aacggctgct ttttcatgac
    23341 acgctgtatc cagccatccg gcaaagaacc gttggaaaaa gccacattgg caaaacgggc
    23401 ggtggtcacc ttgaacttgg aagaatacgc cataatcata tcttccataa tacgtttgct
    23461 ggctcccatg atattcaccg gattggcggc cttgtcagtg gagacacaga agaagtgcct
    23521 aggcgggtaa acggccaaca ggtcaaggaa tctttttgcc ttgatatcat tgttttcaat
    23581 gagtgcctgt accgaatatt tgtccttctc actacggaca tgcttgtgag ccgaaaaatt
    23641 cgccacaatg tcaaagcctt tctcctcacg gaagatcctt tcaaagatag gatcggcaaa
    23701 gttcaaggta tatgcccgat attccgcagg tacatacatg ccgtatgtgg aacgcaggtc
    23761 acgtgtcagt tctgccaatc cgttctcgtt caggtctatt acaatcagtt tggagggctt
    23821 gaacggcaag actgctttaa tgaaagaaga accgatggaa ccggcacctc ctatgacgca
    23881 tacactttta ttccttattt ctgcttgaag cgtttcttta ttagcttcaa tatctgctgc
    23941 aaacatactt gtcggacgac aaatcacatg gtctgcaatg aattgctgta aattaaacat
    24001 ggatttatta ggattagcat ctcattttga cacatcctat aaagaaaacc gcattaaagc
    24061 agtttcctta taaattgggt caaaaattgg attatctttt aatgcttatt taacgaaaaa
    24121 gtaagatata ttcccgagca aagtaagtag acttaaatcg caaagtaagt gaacttactt
    24181 tgcccacgaa catatcttac ttttttccac acttgtcacc ggtttttcac ctccggtcat
    24241 aaccgctttc tcggtcgtct tgcccaagcg ttattgatac gcgcacggat attactgaca
    24301 gtcttgcccg atacgaacaa aggtgtgaga ggaaagaaca acgagataaa acgctccttc
    24361 accatctctt ccgaagtaat cttcggttcc cgttcgccca tcttaactat aaccctggcc
    24421 agttccaccg cattggtaca ttctgctatc tgtaccagat agatacgtaa atcctccacc
    24481 ttatttatat aagagaaaag gcgcgtagcc tcgggagata aagcaggttc cttgtccttg
    24541 cttacatcat ccttctctag ttccgcctca tcaccataat aattctgtgt ggcggaagta
    24601 gcattgggaa gaatctggtt gctgcctcca taaatgttga agacgatgct gaagtgtgtc
    24661 tcattatcca taagcttatt gtttgaatga ttcgtcaacg ggtagttaac ggtcagtcaa
    24721 tagctagtga acggcagtca acagttagta aacgataata aatagatttt tttacggtat
    24781 tttcccgcat taattttgtc gtgtcggaag gatgaacgaa catcccggaa acacaaaact
    24841 tttaaacttt attttattat gattgattac agtgtattta tgatgggcaa cccgatggat
    24901 gtcgatgccg cccaaaaagc gtatgcaaaa gctcaagttt ctgaaatcat gccattcagc
    24961 cagtttgtca aacacattgc cgaccacaat ggcgtattca ctcgcggaac ggtaaaaggt
    25021 gtaatagccg atatgtgcga gtgccttgta gagatgcttc tggagggaaa gaaagtacaa
    25081 ctggctgaat tgggtaattt ctggatttct ataggctcgg aaggtgcgga agacctgaag
    25141 aaatttacag aaagcaacat caccgccgtc aacattgtgt tcacgccggg agaagacttc
    25201 caaaatcttc gttcccgcgc cactttcaat cccgtagcaa gccgcatagc ccaagccgcc
    25261 accctgaagg ccgaaaaggc cggtaaaggc acagtcgact tggatgccgc caaaggaaag
    25321 acctcggctt ccacgaatga aaacaatccg tcattatgat aaaataccac gttttctcga
    25381 tgggaaatgc gtccgacagg acgatgccca agaaagcata tgcaaagtgt gtggccaacg
    25441 aaaaggtttc gcataagaaa ctcgtaaaga aagtgacgga acatctccgc tttttctcac
    25501 acggcatgat ggaagcggtg ctggaggaag tcttcaaccg cctgtccgag catcttgccc
    25561 aaggcgaccg agtcaccctg gacggcctcg gaacattcag tgtctccctg aaatgcgaag
    25621 gagccgcttc ggaggctttg ttctccaaga agaacatcaa gggcgcgcac atcgtgtttg
    25681 ccccgtgtcg caaactcaag gaaacatttg cagatatgga atataaaatg gctccacgaa
    25741 tcttttaacg tcatggaact tatattattc atctatttaa agacaaagcg tatgaaaaag
    25801 aactggaaaa atgtactgct gtacatcgtc cgcatcattg agctgcttat tacaggcgct
    25861 gccggaggag cgcttggaag cggtttatga gaacggtttc gttgattatc gtgcactgct
    25921 ctgccaacaa ggcgggcagt gccttgcgag cagaggacat tgaccgctac catcgttcat
    25981 tgggctggaa gtgctgtggt taccactatg tgattcctac agacggaact atagaagccg
    26041 gacgcccacc gaaaatgatc ggcgcacatt gcaaaagcca caacagtcac agtataggta
    26101 tatgctatat aggtggtctg gatgccgacg gaaagactcc gaaggatacc cggacggaag
    26161 cacaaaaggt agctctgaga aaactgattg aacatctgca tcagcgttat cccaaggcat
    26221 tgattgtcgg tcatcatgac ttgaatccgc aaaaaacctg tccctgtttc aatgtcactg
    26281 ctgaatatat agatttgcaa ccttagttgc gtctgtagtc ttatctgcca tccatcgtcc
    26341 tgcaagggat gtgtggatgg ctttaattaa actaatcaat tttttcaaac ggaaacgcat
    26401 gaagatagct cacagccacc gtcatatttc cgaaagcgaa taccagcctt gtattgcggt
    26461 gcaaacgcat gatgcatcct tccttccccc ggaaaacacc accggtgata cggattcgtt
    26521 gctttttctg aagatagtcc tccaaaggcc ggttcatcag ctcgatattg taaggcatgg
    26581 attcatacaa atagataaat tcttccatct gacggtgagg gattaccgcc gcacggtggg
    26641 tgttatagtc cgtcaccaga tactggcggg gaagcatggc agacagaata cattccaact
    26701 gccccaaggg ggcacataca aacagccaac cgttgccttc aattcctttc tcgtccgtca
    26761 acgtattcag tttttggatg gagccggtag caaaagcctc tttcacgatc cgtgcagagt
    26821 cacggcgcac ggtatattcc tctttggtat aagcacattg ctcgaaacgt tttctatgat
    26881 cggtggcagt gtaagaaaac accttgaaac aaaaaaatct ctcttctacg gtacctgatg
    26941 gtgtacgaag ccgaacagct ttcctgccac tgaaaacact gatatagcgt ttcagttctt
    27001 tgttggaaag atacaggtaa taccaactga attcaggata ttcttttcct attcccgcca
    27061 ttggcgtgat tccttcattt gaccccaggt ctgagccgga agcgattgaa ctgcagagca
    27121 gtaacttagg cgcttcgccc gttatgtctt gatttgaaag gaacgcttga ttttcaagct
    27181 ccatactatt ttctgttacc atcaaaacat tactttttat gtatgtcttt ttggggttct
    27241 cttagtaaga gaaccccaaa aagacatata ctgctgacaa taaaatattt acgcataatc
    27301 agagatggat aatttgcaaa caaatatcat aagaatcctt atcagagact gattcctgaa
    27361 taaaatattt ccgtatttga attattatag ctacatttgc agcggaatgg ggttctctta
    27421 ctaagagaac tccatttttt ttattctaac acattcattt tcaagacaaa tccaagaaag
    27481 cagaaaaagg gatacataaa ttccttttcc gcactcatcg aaaggacaaa cgataaaaca
    27541 caaaagcggc cacttacgat aaaaatcgaa agtgaccgct aaaaagagat ttatttctct
    27601 gatataagga tctatcagtc cagggttact tcaccacaaa ccctctctta tccagataag
    27661 ctttgaattt atgcaaatat tcttcatccg gaccatcaaa gaaggataca ccggatgccc
    27721 cgttattgta tgcttcatcc agcacctctt caaaattgtc cttaatatca ccaaacatca
    27781 gtccggcata tatcttggca cgaccattca ccgtttcaac gctttccttt accgaacgcc
    27841 cgatccattc aggaccttca taatagaatt tattataaat catcggataa taagcatcca
    27901 gcgtccattc tccccaatct tggcgtacca tgtgacgagc catggacggt cccgggaata
    27961 cggcggcaga aatagcttta tgatccgctt tcactgcttt agtgatggca tccaccacac
    28021 gagtgatggc atccagacgg aaattaatcc aactctggtt ttccatcgga tactttaatt
    28081 ccaacggatc ctgtcctgtt ttagctttaa acaattcacg gcatacatca caataacaat
    28141 agtcatattc cggcaactct tctttctgct cgataccata gtttttccat aagctgacag
    28201 gcaagattac atccggcata cggacataat ccagatgaac accatccacg tagggtttat
    28261 gagcttcctt tacatagtct tctgccagat attcggccac accttggtga ttagggcaca
    28321 agaagcgata ataatccacg taggccggtt tgtcgtgaca agactcgcct ttacggttca
    28381 cggcatacca gtcgggatgc ttgtccagca gttccctgcg gttcatcgtc catttccaat
    28441 aatgcgcctc caatccggct tctttgcaga ggcggtaaat attctcattg tatccctcga
    28501 acatgacacc cgaaatacca cattctttca acaacgcaaa ccacttttgc cattcggcat
    28561 ccgaacggtt attcagacgc atccacaacc agtttttaac ttcacgggca ggtatctttt
    28621 ctgtccggaa acgtccttca ttattgatca cataacggat tccttcagca ggattggtta
    28681 tagctatctg atacgtgttc tgagtcgctt ccaccgcaat ccgggcatca gccggaagat
    28741 ctttcaactc tttatcagtc aaaaagaatt gttctgtggc acgcagataa ttatgttgtt
    28801 tactataatt atcctgttgt gcgtagaaca tggcccacag caatttataa atggcctgat
    28861 tgtacgggta aaccaactca tcttgcgagg ttcccacttt cttgtctacg aaataaagat
    28921 atccccaacg gtcgggcatg tgcatatcga ttcttccggt aggagtccat acccaatttt
    28981 cctcgggtcc tttctccttc agccactgta cacgcgaaaa gttgatgcgc caggtattgc
    29041 cagccttcaa cggattgtta aagttcatgg tcagcgcctg atgaggaatg gccatttcca
    29101 cactccaata cttatcttta tcttttgatt tattcagtgt accttcgcaa tggatggcag
    29161 tcttcaatcc ggggcagtcc cattgcacca tgaaatttcc acccgaacga taaggtttgt
    29221 ccagcatcag atcgaaaatc acgccacgcg cattggtttc tatttcaaaa taattgtgtc
    29281 cgtcgctatc cggatcaata aacacttcaa agtcattgtc ataatagatg atggtatcac
    29341 gctgggtaag acgcgccttg atatcctctt cttgaagaac agctcctaca tataaaaatt
    29401 catcatccca cagcatcttg gcggtagttt catatttggg agtcgggaat ccttctccgc
    29461 ttatatctac aaacggggca gtagacgccg ccttgttcca ggaactttca ttcagtttac
    29521 catctatttt caactttcca tccggacgat aacatacata agtacgcggt tcggtcagaa
    29581 aacgctcata ttgttcaaaa aggctttgtg ccattgccgg aaaagtaacc agcagaagta
    29641 acagggtata aataagtttc ttcatgtatt tttcagattc aagttagtta ttatcttgca
    29701 cttgtcccac tccgcgatat agtttgatcg gtccatccag caacacggcc agcacggtaa
    29761 tctgctcatc ctgcacctgt tggggtacat caatgtagag attacccggc actgaattcc
    29821 aataattttt attgtagacc ttgtaattca acatagctcc gttaccaacc acccatatac
    29881 ggttcacttt gttcatcagc ccttttactt ccaccggacc gttaggtttg taaggaaggt
    29941 ataaatacaa aatatccccc gccttattca gtgtggtata tccctggaaa tgctcggtag
    30001 gaatacctgc gcgagtttca taaatagctt ctttatgctt cttggtccat cggccgaact
    30061 ccttcaacac agcgatctgt tcttcaggaa tggaaccgtc ctctttggga ccgatatcca
    30121 ataaaagatt accacccatg ctcaggcagt ctacaaatgt acgaagcagg atatagggtg
    30181 atttatagtt gctgtctgta tgctgatatc cccatgaatc attcatggtc atacaaagtt
    30241 cccaatattt atcttcggga cgcaccaccg gcactccttg ttcgggagtg gcatagtcac
    30301 catacccctg tatacgcgag ttgataatca catttttatt atccgaacga agcaaatcta
    30361 caattccttt ggaattccat gcttccgaac tttgctccca atctccgtca aaccaataca
    30421 gatccggttt ccaggtcttg ttcagctccg ccaattgtcc gaaattgaac ttgttgaatc
    30481 gggcccaacg ttcaggatca tttttataac gtacttccgt acgggttttg ttgggataat
    30541 caggatgcga ccagtccaat aaagaataat agaaaccaag cttcaatcct tgttttctca
    30601 cttcctttac aaagggagcg ataaggtcac gttttgccgg agtgcttttc acgacgctga
    30661 tatctcctac tttggtatcc cataacgcaa ctccgtcatg gtgcttggtg gttatcactg
    30721 tgtatttggc cccactctct ttgatcagat ccacccagtt tttcggatca tacttggagg
    30781 ctgtgaaacc tttttcctgc tccatgtatt catcgtaggg caggtagttg ttaaagaagg
    30841 accagctttc ggacactcct ctaacagaat aaatccccca atggataaaa atacccaact
    30901 tggcttgtga aaaccattcc attcttttgt ccttttgctc ggctgtttca gtctgcggcg
    30961 tatcctgtgc ccgtaaaggg gaagctgcaa tcagcaaacc caggaacgct aacgataatc
    31021 ggttcttttt catatataat aggtttgatt agttaggata gcatgtcagt attattaaaa
    31081 tttacagcta tataatggac aaagataatg tatttttata ttttattcta tctttgcacc
    31141 cctaaaacag aacaaatatg agcgcaaaga aaaagaaaca atccaatagt tccctgagag
    31201 tcatcattat tttagtatta ctgggacttt tggcatataa acatcaattg tttgacggga
    31261 aactgcttga aaatatcccc actatcgaaa gcaatgaaga aaagccagaa atactgacct
    31321 cgccccaaca tggcggtgca ttggaaatcc cgacgatgca atcgggcaca ggcggacaga
    31381 tattgaaacg taaaggatat accctatctt ataatgccga ttacaaaact ccacaatggg
    31441 tagcatggga gcttactaaa aaagaaacaa aaggaaaaga agggcgaaca gacaaattct
    31501 tgcccgaccc ggacgtacgt ggagccaaag catatacggg agattataca aaatcaggat
    31561 acgaccgggg acacatggcc cctgccgccg atatgaaatg gagcaaacaa gccatgaaag
    31621 aatcttttta tatgagcaac atttgtccgc aaaaccctaa tctgaaccgc ggtgactgga
    31681 atgacctgga ggaaaagtca cgccaatggg caaaaaaata tggagcagtg tacattgcct
    31741 gcggccccat atatgatact aaacgcccca aacgaatcgg caacaacaaa gtggcagtcc
    31801 cccatgcttt ctataaagtc atattgataa atgataagaa aaatccgcaa gccataggat
    31861 ttatcttccc caacagcgcc ggacataagc cgctgaagaa atatatagta acagtggaca
    31921 gcgtagagaa aagaacgaat atagatttct tccctgccct gccggatgag gtagaaaaca
    31981 gaattgaagc agagagggta caagagttac cgtaacccat cacatacgta cgtgtggcgc
    32041 aatatatacg tatgcatagc cctacactga cgtatgtgaa gggctacacg tacgtacgtg
    32101 atttatttca cttccaacac cacgatagac ttggcaggaa gagtcacttt caagcttccc
    32161 ttattaacct tggctccggt aaattctttc ggggcaacca cactcggttt ctcgaaacta
    32221 ttgtaatcac ctatattgtt agcggtcaaa atacggccgg taacactctt agctttcacc
    32281 tcacccagat tcaactctat ttcctgcgat tcctgcaaat ctacattaga caaggaaata
    32341 tgaataaaac cgtttgcatc ccgtgaagcg gtagcactta ccatcggaac aatgcggtcg
    32401 tcacgtacca ccttgcgttc acagttcagt tccaaaggaa gataagtagc atcttgatgc
    32461 actttataca tttcaaagac atgataggtc ggtgtcaaaa ccatcttgtc ttccttggtc
    32521 agaatcatag attgaagcac
//
