LOCUS       gnlProkkaKCEKGKEI_356  10536 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KCEKGKEI_356.
ACCESSION   gnlProkkaKCEKGKEI_356
VERSION     gnlProkkaKCEKGKEI_356
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:49:03
            Original ID  :: gnl|Prokka|KCEKGKEI_356
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10536
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10536
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4261:5049]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4262..5049
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..10536
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10536
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(45..641)
                     /locus_tag="ctg88_1"
                     /transl_table=11
                     /translation="MIRMSEQKDMSGDKTLSGGGFNINPVDIIMYLLSKWYWFVLSVSL
                     FGGYAWYQYAKLPFIYSRSATVMIKDAYSNNIGRGLDRFNTYSYTNVSNEILQFQSHKL
                     MRDVVNRLHANVCYLIMDDLREEELYTQAPVKVSFPEEEDHLDFSLTVRIQNRKQVRLS
                     DFSTDATSITLTANLGDTIQSPIGKIVVSPTLYYR"
     CDS             complement(654..1463)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 72.7;
                     E-value: 3.7e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg88_2"
                     /sec_met_domain="Poly_export (E-value: 3.9e-14, bitscore:
                     42.2, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTIKLACLLAIIIFSSCASRKDFVYLQDMDELQEYPMVQKYEA
                     IIHRDDRLSIIVNSKNPELSLPFNMSGSRSYSVEADGSISNNEVGVLSDEKEKGYLVDI
                     NGNIDFPVLGQLHVEGLTRRQLTELIKKRLINEELLKDPMVTVNFLNFKFSVLGEVGHV
                     GTFEVKGDRITLLEALAMAGDLTPRSRLDRIAVIREYGNKRRILFHDIRSKDIFTSPYY
                     YLQQNDIVYVEPTNMKATEQAQRKLSTWSMILSFITTITSLVLLTTK"
     CDS             complement(1485..3173)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 221; E-value: 4.9e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg88_3"
                     /transl_table=11
                     /translation="MKELLKKFLQKLTRENLSNTCQLGWKAFKWVMQVTEGYHWLITFS
                     IFSGIFGVVMSLVNVAMSKWIIDVATGAQEGNIYLVATIVALSFLLGMGIKLVSPWIFG
                     KINMRISIRMQNSLSDALMMCSWKGAGKWHTGDLLTRISSDASEVLGMGMGILPNLLVT
                     GLQLASSFIYLWILDARLAWFILGVTPLVLLSKIYFRKVRELSCAQKKMNSEMGTVMQE
                     NLSKRILVRSLGATNYRKQKLHETQEKLFKLGMEQIKFSTFTQGVMGFTFGGGYLCAFL
                     WGIFQLHNHEITFGTMTAFLQLVGQVQGPFLGLISIPPSLIRGWTSVERLMALFEDVEP
                     DEHPVYIDQPLTLNFRKVSFGYEEGQPVLDRFTAAFHPGSSTAIAGPTGTGKTTIIRLI
                     LALVYPEKGRIDLTTDDGRTLSVTPDLRINFVYVPQGNTLLSGTIRENLWLGSPGADEE
                     ALHKVIRLACAEFVFSLPEGLDTKIGEHGYGLSEGQAQRIAIARALLRPGRIWLFDEAS
                     SALDTETTTHLMDNLLQWGKNNTLIFVTHDSRLMERCDQVIHIKE"
     CDS             complement(3170..4252)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_4"
                     /sec_met_domain="NTP_transf_5 (E-value: 4.4e-35, bitscore:
                     111.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISAPLQKAFMLLLRQGLWDRQEDCSALFPLDEKEWNEIHSMARK
                     QTVQGIIYDGIRLLPTEAVPPRKVLLGWMVEVDTLERVNRQHRETIKALQQIYVQSPSI
                     PFLLLKGIGTADFYPHPEHRIAGDIDLWFGNKTQTEQANQRMEKLGLPVKRGTNGEASC
                     LINRVLIEHHSRLIELHNPFLQKEIRQWEAGVFTNSQGKLPSEANHLLLSTHILKHLIN
                     EGIGLRQLCDIAMAFNALHSVTNKNELECICRKWHIHRWNRLLYALLIKYLGVPADLLP
                     FSTSLCPDKLMQEIWESGNFGHGDERYGERPTGKWANKRYTLKRIFHKTHLSLGYAFDE
                     TFWWLAGLALLRFKEMIKKK"
     CDS             complement(4262..4531)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_5"
                     /sec_met_domain="PF05402 (E-value: 4.7e-18, bitscore: 55.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.2e-10,
                     bitscore: 30.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLNSNLILRQVGGEYMIVNPFSETMDMAQVYSLNETAAWLWKQL
                     ENKEFTVDEAGALLCNEYEVNKDTARNDANELCRQWLETGLAIE"
     CDS             complement(4768..5049)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_6"
                     /sec_met_domain="PF05402 (E-value: 1.4e-17, bitscore: 53.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.2e-15,
                     bitscore: 45.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTKEFIKRNIAGEIVLVPSGQTAREFNGMVTLTETGEFIWEHI
                     EEAESFNHLVLLILEEYEVDKDTASQDAAGFIMQLLQAGMIRPTGINW"
     CDS             complement(5046..5486)
                     /locus_tag="ctg88_7"
                     /transl_table=11
                     /translation="MKTVDTKEYISMLRTLIEEGKQVSMIISGSSMAPFLIHARDHICL
                     KSPSGELRKGDMVFYQRSNGEYVMHRIYNVKNEEYYLIGDAQTVIEGPIQREQIFAIII
                     KVKRKGKWIVPEDFQWKFFAHIWPNIIPLRRTIIKTYRFFKR"
     CDS             complement(5505..6380)
                     /locus_tag="ctg88_8"
                     /transl_table=11
                     /translation="MRLNIGPLTIELSGVTEQEIPVNSRLFLDHKPATKEADRYYTFYF
                     VNRLPLPSNDWQITFQRNDIVVFRKEEQETRLLAVGNLNACYALYQERNERDANIYFIE
                     GLKRELQTDTLFISCLCLERPLSVQGCYILHCTFLDYRGQAILFSGPSGIGKSTHANLW
                     CRHIPGTQVLNGDRALLCPLPNGDYEITGWPVCGSSGICHNERRPLEAIVFIEQASDNT
                     IRPQTAMKHFKALCSQVTINWWNPKLTGKALDDLQVLTRQTSISTYACNMNPEAAFTLH
                     RYLTKLEIIR"
     CDS             complement(6393..7499)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_9"
                     /sec_met_domain="PF04055 (E-value: 8e-25, bitscore: 77.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLHDANLLERALVDKANQSRVPITTNFELTPTCTLNCDMCFIR
                     TERSVVERHGGLSPLQQWLDWAEQLQDMGTLFILLTGGEPMLYPHFKELYTRLREMGFI
                     LTLNTNGTLIDNEMVRILQTHKPRRINVTLYGDSRETYGRLCHNPQGYTLCMEALKRLK
                     KADIDVKLNVSIVRKNEKDYDEIIRLAQHLDIPAEVNSYMFPLSRPECGSLRNILTERL
                     DADEAARIEMQYMEYKKGNDMARYMHDLKYTLAHVEGTRACSLECRAAKSSCWINWQGI
                     LTPCVMLDQPAVDLKKIPMTTAWQQLLEEAKELVSHTECEGCHLRPVCNVCYAAAHCEK
                     TITGSMDYLCQMAKAKERIITNYPPVIH"
     CDS             complement(7535..8638)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_10"
                     /sec_met_domain="PF04055 (E-value: 5.9e-31, bitscore: 97.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESLQDINPVERALVNKATANRTPINATIELTPTCNFRCDMCYIR
                     MEKSQAEKRGGLRSIEEWLHIADQLQEIGTLFILLTGGEPLLYPDFKELYIRLKEKGFI
                     LTINTNATLIDDETVRLFQRLKPRRVNVSLYGVTNGTYLNLCHATNGFDRCLEGLKRLK
                     EYGIDTKLNLTLTRQNIKEHRQMLELADEWDLPMLTNSYISVYSRPGCATTLPLDTCRP
                     VPDEVAHAEVEALEHKYGKEYTSYATHVLQQLERGESPVPAEGIGLACRAGKSSAWINW
                     QGVMTPCVDMETPAVSLLSTTVSDAWKQIVTKCEQLPFHKECAGCTLRSICDVCYANAR
                     NEKEQCGGIGYLCRIAKSKKKQMKGSL"
     CDS             complement(9094..9489)
                     /locus_tag="ctg88_11"
                     /transl_table=11
                     /translation="MKKDYQKPMLISEEFIPNEYVAACYNFKALFHCHYGENNTNNHGE
                     PCATTYVDINGIHATGHEGTIEKWGIPILNIDWNGFDLSDAKVGDKIRGIKWTSYDTVN
                     NTGEYNHQGWGEIRSAVEEIPGRPNHS"
     CDS             complement(9830..10219)
                     /locus_tag="ctg88_12"
                     /transl_table=11
                     /translation="MTKKVYTKPELKSEAFVPQTHVAACGDSGTVYKFTCDAPRGTLYY
                     FRDKPASGSQPTIGNRGIWLGNYHPCSAFHEAEAQSGFYWGYVDYNHNQIFEKSELVIV
                     WRGQKGWEGHATKNLDINSWETAKS"
ORIGIN
        1 agttctgctg tctgatacaa gaggataaat tgaattgata gaactcacct ataatataag
       61 gtgggtgaga ccactatttt tcctatgggc gattggatgg tgtcacccag attggctgtt
      121 agcgttatac ttgtggcgtc tgtcgagaaa tcggataacc ggacttgctt cctgttctgg
      181 attctgactg tcaggctgaa atcaagatga tcctcttctt ccgggaatga aaccttgaca
      241 ggggcttgcg tataaagttc ctcctcacgc aagtcatcca tgatgaggta gcatacattg
      301 gcgtgaagac ggttcaccac atcgcgcatg agtttgtgtg actggaattg caggatctca
      361 ttggatacat tggtatatga ataggtgtta aaacggtcca gcccgcgacc gatgttgttt
      421 gaataggcgt cctttatcat gacggtggct gaccgtgaat agataaaggg aagtttggca
      481 tattgatacc atgcatatcc gccgaacaga ctgaccgaca atacaaacca gtaccatttg
      541 gacaacaggt acatgatgat gtcaacgggg ttgatattga atcctccccc gcttaaggtc
      601 ttatctcccg acatatcttt ttgttcactc attcttatca tgtcgtttct tttttattta
      661 gtagtcagca ataccagcga ggtgattgtg gtgatgaagg acaggatcat actccatgtg
      721 ctcagttttc tctgggcttg ttcggtggcc ttcatgttgg taggttctac gtagacaatg
      781 tcattctgtt gcaggtaata gtaaggcgac gtgaagatgt ctttgctgcg gatgtcgtgg
      841 aacaggattc gtcgcttgtt cccatattcg cggatgacgg cgatacggtc cagacgggat
      901 cggggggtca ggtctccagc catggcaaga gcctctaaaa gagtgatgcg gtcgcctttc
      961 acttcaaagg ttcctacatg tccaacttct cctagcacgg agaatttgaa gttcaagaaa
     1021 ttgacggtga ccataggatc tttcagcaat tcttcgttga tcagtcgttt ttttatcagt
     1081 tcggttaatt gtcggcgggt cagtccttcc acatgcagtt gtcccagcac aggaaagtct
     1141 atattcccgt tgatatccac taaataacct ttttcttttt catcacttaa tacccccact
     1201 tcattgttgg aaatgcttcc gtctgcttct acagaatagc ttctgcttcc ggacatattg
     1261 aaaggcaggg acagttctgg gtttttgctg ttcacaataa tactcaatct gtcatcccta
     1321 tggatgatgg cttcatattt ttgaaccata ggatattcct gtagttcatc catatcttgt
     1381 aaatagacaa aatctttgcg tgaagcgcac gaactaaaaa tgattattgc caacagacag
     1441 gccagtttga ttgttttatc cattgtttta taattaattg ttttttattc ctttatatga
     1501 atcacttggt cacatcgttc catcagtcgt gaatcgtgtg tcacaaatat taatgtgtta
     1561 ttctttcccc attgcaacaa attgtccatg aggtgtgtgg tggtctcggt gtcaagtgcc
     1621 gatgatgctt catcaaacag ccagatccgc ccgggacgca acagtgcgcg ggctattgca
     1681 atccgttggg cttgtccttc agacaagcca tatccatgtt cccctatctt ggtatctagt
     1741 ccttccggca gactgaacac aaattcagcg caggccagcc ggatgacttt atgcagagcc
     1801 tcttcgtctg ctcccggact acccagccat aaattctccc ggatggtacc gctcagcaac
     1861 gtatttcctt ggggcacata gacgaagttg atgcgtaaat cgggggtcac actgagtgtc
     1921 cgtccgtcat cagttgtcaa atcgatgcgt cccttttccg gataaaccaa agccagtatc
     1981 agccggataa tggtcgtttt tcctgttccg gtaggtccgg ctatggcggt ggaacttccc
     2041 ggatgaaagg cagctgtaaa ccggtcgagt accggctgtc cctcttcata gccaaaagac
     2101 actttccgaa agttcagtgt cagtggttgg tctatgtaga ccgggtgttc gtccggttct
     2161 acatcttcaa agagggccat taaccgttcc acggaggtcc atccccgtat cagactggga
     2221 gggatggata ttaaccctaa aaaaggtccc tgtacctgtc cgaccagttg aagaaaggct
     2281 gtcattgttc cgaatgttat ctcgtggtta tgcagttgga aaatacccca aaggaatgca
     2341 cataagtacc ctcctccaaa tgtaaatccc atgacccctt gcgtaaaagt ggaaaatttg
     2401 atttgttcca ttcccaattt gaacaacttc tcttgtgttt catgtaattt ctgtttccgg
     2461 tagttggtgg ctccgagcga gcggactaga atccgtttgg acagattttc ttgcatgacg
     2521 gtacccatct cgctgttcat ctttttttgg gcacagctca gttcccggac ctttctgaaa
     2581 taaatctttg acaataaaac aagaggggtg actcccagta tgaaccaagc taaacgcgcg
     2641 tcaagaatcc acaagtagat aaaagagctt gccaattgca agccggtaac cagcaggttg
     2701 ggtagaatgc ccattcccat tcccaacact tcggaagcgt cactgctgat acgggtcagc
     2761 aggtcgcctg tgtgccattt ccctgctcct ttccatgaac acatcattag ggcgtcggac
     2821 agcgaatttt gcatgcggat actgatgcgc atgttgatct tgccaaaaat ccagggagat
     2881 acaagtttta tccccatacc cagcaggaag gataaggcta ctattgtggc taccaggtaa
     2941 atattccctt cctgtgctcc ggtagctaca tcgatgatcc atttggacat ggccacattg
     3001 accaatgaca tgaccactcc gaaaataccc gaaaagatag agaaggtgat gagccaatgg
     3061 tatccttctg ttacctgcat aacccatttg aaagctttcc atcctaactg acatgtattg
     3121 ctcagattct cccgtgtgag cttctgcaaa aattttttca gcaattcttt catttctttt
     3181 ttatcatttc cttgaaacgt aagagggcta atccggccag ccaccagaaa gtttcgtcga
     3241 aagcataacc taacgataag tgcgttttgt gaaagatccg cttcaacgtg tatcgtttgt
     3301 tcgcccattt cccggtggga cgttcaccgt aacgttcgtc tccatgtcca aaattgccac
     3361 tttcccaaat ctcttgcatt aacttgtccg gacagagact ggtactgaat ggtaaaaggt
     3421 cggccggcac gccaagatat tttatcaata gggcataaag taaccggttc caccggtgaa
     3481 tgtgccattt gcgacagata cactctaatt cgtttttgtt tgtaacagaa tgtaatgcgt
     3541 taaaagccat ggctatatca cacaattgtc gtagtccgat cccttcattg ataagatgct
     3601 tcaatatgtg ggtggaaagt aatagatgat tcgcttcgct cggaagtttg ccttggctgt
     3661 tggtaaagac ccccgcttcc cattggcgga tttctttttg gaggaaaggg ttgtgcaact
     3721 ctatcagcct gctgtgatgt tcaatcagaa ctctgtttat cagacaggaa gcctcaccat
     3781 tggttcctct ttttaccggt aatcctaatt tttccatccg ttggttggct tgttcggttt
     3841 gtgtcttgtt tccgaaccac aggtcgatgt ctccggctat gcgatgttcc ggatgagggt
     3901 agaagtcagc tgtccctatc ccttttagca gcaggaaagg gatagaaggt gattgtacat
     3961 aaatctgttg gagggcttta atcgtttccc ggtgttgccg gttcacccgt tccaaggtgt
     4021 caacttccac catccagcca agcaatacct tccggggagg tacggcttca gtcggcaaca
     4081 ggcggatgcc atcgtaaata ataccttgta cggtttgttt tcttgccatg ctgtgaattt
     4141 cattccattc cttttcatct agaggaaaaa gggcggaaca gtcttcctgc cggtcccaca
     4201 gtccttgcct tagcaaaagc atgaaagcct tttgtaatgg ggctgagatc atctttttgt
     4261 cttattctat ggctaaccca gtttctaacc attgtcggca cagctcgttg gcatcgtttc
     4321 gggctgtatc tttatttact tcatattcat tgcacagcag tgctccggct tcatctaccg
     4381 tgaattcctt gttttccaat tgtttccata accaggcggc tgtttcattc aaggaataga
     4441 cctgtgccat atccatggtt tcagaaaacg gattgacaat catatattct ccacctactt
     4501 ggcgaagaat taaattagaa ttgagtctca ttgtctttat attattgcat tatcctattt
     4561 atagttaaaa ttacatcgac cttcacaggc agatgtaatg gggaataaaa tgtaagttca
     4621 ttctattatc cgctgataac atagggtctt gaacttacct gatctaacat tttttacaga
     4681 tccggcgctt ctcgcgaaga aaacgaatct ctcttctaac atttcttatt gtattgtttg
     4741 tcatatctga attgaacaga ttactgttta ccagtttata cctgtgggac ggatcatgcc
     4801 ggcttgcagc agttgcatga taaatcctgc ggcatcttgc gatgcggtgt ctttatccac
     4861 ttcgtattcc tccagaatca acagtactag atggttgaag ctttctgctt cttcgatatg
     4921 ctcccagata aattctccgg tttcggtcag ggtgaccatt ccgttgaact ctcgggcggt
     4981 ctgtccggaa ggaaccagta cgatttctcc ggctatgttt cgtttgataa attctttggt
     5041 tcttttcatc ttttgaaaaa acgatatgtt ttaatgatgg tcctgcgtaa aggaattatg
     5101 ttcggccata tgtgggcgaa gaatttccac tggaaatctt ctggaactat ccatttccct
     5161 tttcgcttca ccttgataat gatggcgaaa atctgttctc tttgaattgg accttcgatg
     5221 acagtctggg cgtcaccgat aagataatat tcttcatttt taacattata aatacggtgc
     5281 atgacatatt caccgttgct tcgctgatag aacaccatat ctcctttccg aagttcaccg
     5341 gaggggcttt tcaggcagat gtggtctctt gcgtggatca ggaatggagc catgctgctg
     5401 cccgagatga tcatgctcac ctgctttcct tcctcaatga gggtacgcag catggatatg
     5461 tattctttcg tatcgacagt cttcataatg gggcgtattt cacattatcg gataatttcc
     5521 agtttggtca gatacctgtg cagggtgaag gctgcttccg gattcatgtt gcacgcatag
     5581 gtgctgatgc ttgtctgtct ggtcaaaacc tgcagatcgt cgagtgcttt gccggtgagc
     5641 tttggattcc accagttgat tgtaacctgc gagcagagag ctttgaaatg cttcatggct
     5701 gtctggggac ggatggtgtt atcagatgcc tgttcgatga atacaatggc ctccaacggg
     5761 cggcgttcat tgtgacagat accgctggaa ccgcatacag gccatcccgt tatctcgtag
     5821 tcgccgtttg gaagtggaca gagcagggca cggtcgccat tgagtacctg ggtgccggga
     5881 atatgccggc accacaggtt ggcatgcgtc gatttgccaa tgccgctagg accactgaat
     5941 aagatggctt gcccacgata atccagaaaa gtacaatgta gtatgtaaca tccctggaca
     6001 gataaaggac gttccaggca caggcaggaa atgaacaggg tatctgtttg cagttctctt
     6061 ttcagacctt cgatgaaata gatgttggca tctctttcgt ttctttcctg atagagagca
     6121 tagcaggcat tcaggtttcc tacagccagc aggcgtgttt cttgttcttc cttccggaaa
     6181 actacgatgt cgttgcgttg gaatgtgatc tgccagtcgt tggacggcaa aggcagacgg
     6241 ttgacaaaat agaatgtata gtaccggtcc gcttctttgg tagcgggttt atggtcgaga
     6301 aacaaacggc tgttaacagg aatctcctgt tctgtcactc ctgacaattc aatcgttagc
     6361 gggccgatat tcagtctcac aatcttcagt ttttaatgta ttacgggggg ataattcgta
     6421 atgatccgtt ctttggcttt cgccatctgg caaagatagt ccatgcttcc ggtgattgtt
     6481 ttttcacagt gtgcggcggc atagcatacg ttgcatacgg gacgaaggtg gcaaccctcg
     6541 cattcggtat gggataccag ttccttggct tcttctaaaa gttgttgcca tgcagttgtc
     6601 atcggaatct ttttcaggtc aacggccggt tgatccagca tcacacaggg ggtgaggatg
     6661 ccttgccagt tgatccagca tgaactcttg gcagctctgc actccaaaga gcaggctcgt
     6721 gttccttcca catgggcaag cgtatatttc aagtcgtgca tgtatcgtgc catgtcattc
     6781 ccttttttgt actccatata ttgcatctcg atgcgggccg cctcgtcggc atccagtctt
     6841 tcagttagaa tgttacgcag acttccgcat tcggggcgtg agagaggaaa catgtatgag
     6901 tttacttctg ccggaatgtc cagatgctgg gccagacgga tgatctcgtc gtaatctttt
     6961 tcattctttc gtacgatact tacgttcagt ttcacatcaa tgtctgcctt tttcaaccgt
     7021 ttcagggctt ccatgcacag ggtgtatcct tgcggattgt ggcacaagcg tccgtaagtt
     7081 tctctgctgt ctccatacag ggtgacgttt atccgccgcg gcttgtgggt ctgcaagatg
     7141 cgtaccattt cgttgtcgat gagtgtgccg ttcgtattga gagtcaggat gaatcccatt
     7201 tcgcgcagcc gggtgtacag ctccttgaag tgtggataga gcatcggttc acctccggtg
     7261 agaaggatga agagtgtacc catgtcttga agttgttctg cccagtcgag ccattgttgc
     7321 aaaggcgaca aacctccgtg ccgttccacc acgctgcgtt cggtgcgtat gaagcacatg
     7381 tcgcagttga gcgtacaggt gggagtcagc tcgaagttgg tagtgatcgg gacacggctc
     7441 tgattggctt tgtccaccaa tgcccgttcc aaaaggttgg catcgtgaag atgatccata
     7501 acttggaatg tatatgtatt tatgagaaaa gtctttatag acttcctttc atttgtttct
     7561 ttttactttt tgcaatgcgg caaaggtagc cgatgccgcc gcattgctct ttttcattgc
     7621 gggcattggc atagcagaca tcacagatag agcgtaaggt acaacctgcg cattctttat
     7681 ggaacggaag ttgttcgcat ttggttacta tttgtttcca ggcatcgctt acggttgtgg
     7741 aaagtagcga aacggctggt gtttccatat cgacgcacgg agtcatgacg ccctgccagt
     7801 tgatccatgc ggaactttta cctgcccggc aggcaagtcc gatgccttca gcaggtacgg
     7861 gagattctcc acgttccaat tgctggagga catgagtggc gtatgatgtg tattccttgc
     7921 catatttatg ttccagtgcc tcaacctcgg catgtgccac ttcatccggt acggggcggc
     7981 acgtatcaag gggtagcgtg gtggcgcatc ccggccgtga atagactgaa atgtaactgt
     8041 tggtcagcat aggtaagtcc cattcgtcag ctagttccag catttgccgg tgttctttta
     8101 tattttgtcg tgtcaaggtg aggttcagtt tggtatctat gccatattct tttaatcgtt
     8161 tcagtccttc caggcaacgg tcgaaaccgt ttgtcgcgtg gcacagattg agataagttc
     8221 cgttggtcac accatataac gagacattca ccctccgggg tttcaaacgt tgaaacagac
     8281 gtactgtttc gtcatctatc aaagtcgcgt ttgtattgat ggtgaggatg aatccttttt
     8341 ctttcagccg gatatataat tctttgaaat caggatagag taggggctcg cctcctgtca
     8401 gtaagatgaa gagcgttcct atttcctgta gctggtcggc aatgtgcagc cattcctcta
     8461 tgctccgtaa tcctcctctt ttctcggctt gtgacttctc catgcggata tagcacatat
     8521 cacaacggaa attgcacgtc ggtgtcaatt caatagtggc attgatcgga gtacggtttg
     8581 ccgtcgcttt gttcaccaat gcccgttcca cagggtttat gtcttgcagg gattccacta
     8641 ggataatgat tttttttcaa agaaaagttt ttgagtctag tgtattggat ttcatttact
     8701 tccgtggtcg tatatgttac cgaaatttgt ctcgatggaa aatatataga ttatcttccc
     8761 tttttgaagc tcaacaaaag ttaatactta atttagagca tatccttttt ataaggcacc
     8821 agaattggca tctcacaaaa agatattatc aaattcgatt gatttttaac tattggcata
     8881 caaccaagtc tatattttac gatgatagac ccaaagatag ggaaagtaga atctttcaag
     8941 gtcttcattg ctttgcataa ttcgtaaatt ttgattcgca gcgaagatag atattttaga
     9001 accctaattt gagaggttta cagtatagac tttactttta aggtccaagt ctatactgtt
     9061 atttgatgcg aatttcataa ataggggaat gtcttaagag tggttaggac gacctggtat
     9121 ttcttcaaca gcagatctga tttcacccca accttgatga ttgtattctc cagtgttatt
     9181 tactgtatca tagctagtcc acttgatgcc tctaatcttg tcacctactt ttgcgtcact
     9241 taaatcgaat ccattccaat caatattgag aataggtata ccccattttt ctatagtccc
     9301 ttcgtgccct gtagcatgga taccattaat atctacatag gttgtagcgc atggttctcc
     9361 atgattgttt gtattgtttt ctccataatg acaatgaaat agtgctttaa agttatagca
     9421 tgcagctaca tattcgttcg gaatgaactc ttcgctaata agcatcggtt tttgataatc
     9481 tttcttcata ctattttttt cttttttgat tcctgtttcg gaggaaagga aatcagaaaa
     9541 ggtttgaagc gaaatagtga ttgggtcccg gagaaactcc ggtgtgaaag aattttgaaa
     9601 taattgatat attgcgattt accatctaca atatgatcct ttcattttcc ttttcattac
     9661 actaattctt tgcagctcaa acgatattct gacttagttc ctccagtagt ctgatcatat
     9721 attatttaat ctctatttct attaatgaga atcaataaat ttatctaagc gttaggaatc
     9781 aagattgaaa taaatgaata agattgctat ttactgtttt atttaccgat taggatttag
     9841 cagtttccca agaatttatg tcaaggttct tggtggcgtg accctcccag cccttttgtc
     9901 ctctccaaac aatgactaat tcacttttct caaatatctg attatggttg taatcaacat
     9961 atccccaata aaaaccagat tgggcttcgg cttcatgaaa tgcactacat ggatgatagt
    10021 ttcctagcca aatacctcga tttcctatag tgggttgtga accagaagca ggcttatctc
    10081 taaaataata caacgttcct cttggtgcat cacaagtaaa cttataaaca gttccactat
    10141 ctccacaagc agccacatgc gtttgcggca cgaaagcctc gcttttcagc tccggctttg
    10201 tataaacttt ctttgtcatc ttttttttct tgttttgcca gacttcttat tctgtaagag
    10261 ggcaaaagtt tgaaaagaga aaaacatgac cgagttctgc aagaactcaa tcaataagaa
    10321 tcaagaataa aaaggatgaa acgactgtga tttacagtct ttaccgattt acggagataa
    10381 atatccggat gtgacatgtc gctttcggct tgttcacgtt ccatctccaa attcctaaca
    10441 tcttacaatt ttctctttac tatgaaactt tcatatagcc aagttcttgc agaactctgt
    10501 ctgttattaa ataaattatc tatctcatac tccgta
//
