Select genomic region:
Overview
2.1
5.1
8.1
8.2
9.1
13.1
16.1
23.1
23.2
34.1
34.2
78.1
78.2

### Identified primary metabolite regions

c00002_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_2)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 2.1 | Acetyl-CoA_pathway | SCFA | 62,911 | 97,046 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%

c00005_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_35)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 5.1 | GR_eut-pdu-related | Putative | 72,813 | 109,019 | Propanediol degradation S. enterica | PDU | 37%

c00008_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_64)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 8.1 | Others_HGD_unassigned | Putative | 4,323 | 23,858 |
Region 8.2 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 51,824 | 85,040 |

c00009_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_71)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 9.1 | succinate2propionate | SCFA | 1 | 19,997 | Succinate to propionate B. theta | PRO | 33%

c00013_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_75)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 13.1 | Rnf_complex | E-MGC | 40,918 | 65,929 | Rnf complex C. sporogenes | RNF | 100%

c00016_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_78)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 16.1 | Fumarate2succinate | SCFA | 60,786 | 79,653 |

c00023_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_85)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 23.1 | TPP_AA_metabolism | Putative | 41,195 | 70,032 |
Region 23.2 | Others_HGD_unassigned | Putative | 176,324 | 198,336 |

c00034_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_96)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 34.1 | Rnf_complex | E-MGC | 85,955 | 112,489 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%
Region 34.2 | Putrescine2spermidine | Aliphatic_amine | 138,613 | 161,861 | Putrescine2spermidine E. rectale | SPRM | 100%

c00078_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_140)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 78.1 | PFOR_II_pathway | SCFA | 6,288 | 29,824 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 78.2 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 34,077 | 71,727 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 2.1 | Acetyl-CoA_pathway | SCFA | 62,911 | 97,046 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%
Region 5.1 | GR_eut-pdu-related | Putative | 72,813 | 109,019 | Propanediol degradation S. enterica | PDU | 37%
Region 8.1 | Others_HGD_unassigned | Putative | 4,323 | 23,858 |
Region 8.2 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 51,824 | 85,040 |
Region 9.1 | succinate2propionate | SCFA | 1 | 19,997 | Succinate to propionate B. theta | PRO | 33%
Region 13.1 | Rnf_complex | E-MGC | 40,918 | 65,929 | Rnf complex C. sporogenes | RNF | 100%
Region 16.1 | Fumarate2succinate | SCFA | 60,786 | 79,653 |
Region 23.1 | TPP_AA_metabolism | Putative | 41,195 | 70,032 |
Region 23.2 | Others_HGD_unassigned | Putative | 176,324 | 198,336 |
Region 34.1 | Rnf_complex | E-MGC | 85,955 | 112,489 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%
Region 34.2 | Putrescine2spermidine | Aliphatic_amine | 138,613 | 161,861 | Putrescine2spermidine E. rectale | SPRM | 100%
Region 78.1 | PFOR_II_pathway | SCFA | 6,288 | 29,824 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 78.2 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 34,077 | 71,727 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_1)
  c00003_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_13)
  c00004_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_24)
  c00006_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_44)
  c00007_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_53)
  c00010_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_72)
  c00011_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_73)
  c00012_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_74)
  c00014_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_76)
  c00015_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_77)
  c00017_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_79)
  c00018_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_80)
  c00019_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_81)
  c00020_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_82)
  c00021_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_83)
  c00022_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_84)
  c00024_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_86)
  c00025_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_87)
  c00026_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_88)
  c00027_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_89)
  c00028_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_90)
  c00029_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_91)
  c00030_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_92)
  c00031_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_93)
  c00032_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_94)
  c00033_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_95)
  c00035_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_97)
  c00036_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_98)
  c00037_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_99)
  c00038_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_100)
  c00039_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_101)
  c00040_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_102)
  c00041_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_103)
  c00042_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_104)
  c00043_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_105)
  c00044_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_106)
  c00045_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_107)
  c00046_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_108)
  c00047_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_109)
  c00048_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_110)
  c00049_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_111)
  c00050_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_112)
  c00051_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_113)
  c00052_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_114)
  c00053_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_115)
  c00054_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_116)
  c00055_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_117)
  c00056_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_118)
  c00057_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_119)
  c00058_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_120)
  c00059_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_121)
  c00060_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_122)
  c00061_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_123)
  c00062_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_124)
  c00063_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_125)
  c00064_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_126)
  c00065_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_127)
  c00066_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_128)
  c00067_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_129)
  c00068_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_130)
  c00069_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_131)
  c00070_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_132)
  c00071_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_133)
  c00072_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_134)
  c00073_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_135)
  c00074_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_136)
  c00075_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_137)
  c00076_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_138)
  c00077_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_139)
  c00079_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_141)
  c00080_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_142)
  c00081_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_143)
  c00082_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_144)
  c00083_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_145)
  c00084_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_146)
  c00085_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_147)
  c00086_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_148)
  c00087_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_149)
  c00088_gnlPro.. (original name was: gnl|Prokka|MHLMBBNI_151)

Compact view
c00002_gnlPro.. - Region 1 - Acetyl-CoA_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 62,911 - 97,046 nt. (total: 34,136 nt) Show pHMM detection rules used
Acetyl-CoA_pathway: (CdhC and CdhD and minimum(8, [CbiA, FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane, Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter, THF_DHG_CYH, THF_DHG_CYH_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00005_gnlPro.. - Region 1 - GR_eut-pdu-related
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 72,813 - 109,019 nt. (total: 36,207 nt) Show pHMM detection rules used
GR_eut-pdu-related: (minimum(1, [Gly_430_pcre, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2, [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not EutC and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00008_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 4,323 - 23,858 nt. (total: 19,536 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00008_gnlPro.. - Region 2 - Others_HGD_unassigned,TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 51,824 - 85,040 nt. (total: 33,217 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00009_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 19,997 nt. (total: 19,997 nt) Show pHMM detection rules used
Region on contig edge.
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00013_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 40,918 - 65,929 nt. (total: 25,012 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00016_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 60,786 - 79,653 nt. (total: 18,868 nt) Show pHMM detection rules used
Region on contig edge.
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00023_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 41,195 - 70,032 nt. (total: 28,838 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00023_gnlPro.. - Region 2 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 176,324 - 198,336 nt. (total: 22,013 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00034_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 85,955 - 112,489 nt. (total: 26,535 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00034_gnlPro.. - Region 2 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 138,613 - 161,861 nt. (total: 23,249 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00078_gnlPro.. - Region 1 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 6,288 - 29,824 nt. (total: 23,537 nt) Show pHMM detection rules used
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00078_gnlPro.. - Region 2 - GR_AA_metabolism,Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 34,077 - 71,727 nt. (total: 37,651 nt) Show pHMM detection rules used
GR_AA_metabolism: (minimum(1, [Gly_430_pcre, Gly_8-9_TMA, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and not NRDD and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.