LOCUS       gnlProkkaCGDIBNIP_126  15229 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGDIBNIP_126.
ACCESSION   gnlProkkaCGDIBNIP_126
VERSION     gnlProkkaCGDIBNIP_126
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 04:58:42
            Original ID  :: gnl|Prokka|CGDIBNIP_126
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15229
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15229
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3810:5229]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3811..5229
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15229
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15229
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(42..764)
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MDEEYYLLTLMAIARELNVFSIREADVHLAAGLPLTWIRNQREDF
                     RSYLLQNPEVHYRFNSKEYHLRFVGCSLYPQGYPAIVNRLGDFKGTNLLADIGNGTMNI
                     LYINNKKAQESRCWTEKFGVNQCMIAAKNAVLDNFGVKIEESTVEQILRFGTADISASY
                     LDCITAVARQYVTDIFATLRKYEYNPGLMRLYVVGGGGCLIRNFGAYDKSRVTILDDIC
                     ATAKGYESLAYMSLKRRG"
     CDS             1497..2252
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MRNVLATDIKNNIRSIRFILGIFLIVSATLMSEHEMLQKIINAGG
                     SAEGPGWFVAYTYCMNSVNMLLFVPIAVAFAGGENTEAELHSRFFLFSYIRSGRKQYLV
                     GKAAGLLVSGGLTAFLAMVFLLVICILRFGQYPSLIDGNYEMAVLVGRTAVSFLRLFLN
                     GAFWALIGGTSAVITKNRYMSYAVPFILYYVLTVFQERYYQKAFFLSPRYWAASIYYND
                     IFCIAILAVGSFLTALIFMCAIERRLRYA"
     CDS             2677..3138
                     /locus_tag="ctg42_3"
                     /transl_table=11
                     /translation="MLGYGGGESITVPVSIKTMESSTPYMCAAIVFGLVLLYTLFIAVL
                     MLFLNLAAGNMAGVIGAFAVSLYGLLLNPDVFRKLFHFTESQEYRANVFCGWLSPLNQA
                     TFPMHSFGYDYLPGIGMSMFIFAILIIALIGLSAVRIKGYNFSFTQTNE"
     CDS             3151..3792
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 165.4; E-value:
                     2.9e-50)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_4"
                     /transl_table=11
                     /translation="MEYAIRLKGLTKSFQKEKVLKNITHDFEKGKIHGIMGFNGSGKTV
                     MFKCICGFLQPESGTVLVGGKQIGKELDFPDSVGIIIENPGFFLDLSGFANLKRLASLK
                     HRISDDDVRATMRALGLDPLSKKKVGQYSLGMRERLGIAQAIMEDPELLILDEPFNGLD
                     KQGAGEVCELLRGLKERGKTILIAAHNMLEIEWLCDTICEMDAGVLTQIK"
     CDS             3811..5229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_5"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     3.1e-14, bitscore: 43.5, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.1e-16, bitscore: 51.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.2e-13, bitscore: 41.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKVLIKCIQTPMQKYFYDRSLDSVVMVNDEEYQILKTVEKTKLV
                     PDGVLRRFVKSGLLRETAIEEIEHPETENLHLLAEHYMGNLILQVTQQCNLRCKYCAYS
                     GNYYNRSHTSNRMDFETAKKAIDFYLKRSEKADQLALSFYGGEPLLEFELIKKCVSYIL
                     QRKGDKKILFTMTTNGTLMTEDVIEFLVKYEFNLMISLDGDKKSHDINRRFKTGKGSFD
                     IILENLSRLKAYNEEYYSKVLFNCVISSSSDLENIYRFYSEEELFEAGTVNFNYVNPVG
                     LKDETLSRITQKNFRVHRLAYIKMILSVLEKRKWDAQSRLLRRELQDIELLYEQLHSHV
                     AEGKKTHHGGPCIPAVRRLFVDTKGEFFPCERVSEEDSEMCIGSLDSGFDFDKMSFLLN
                     HGKMIKEKCLGCWNLRMCAYCLVQIPKDNQILTENMLLQQCENSKESTLLLLYKLCILV
                     EFGYKGNENLQVLK"
     CDS             5240..6289
                     /locus_tag="ctg42_6"
                     /transl_table=11
                     /translation="MEKLVVFPLNNDTEILIKGLKENKLYQVVAVSSYIEDRSRLELLQ
                     KKSSIYCSTEFEECLTRADAIVFSENTMGYSYDGYQKRVQMALDSGKKIYAGLALLDKI
                     QIDRDKVCILQESELSDEVVSPNKKEIDIPVISVMGLGENCDKFQLQVKIKKVIEKQGY
                     RVLALCSNVLGGFLGMENLPGFLYSKFMSYPEKIIALNHWIHTKVKQQEYDVILVGCPG
                     GVSEFEKYETNYFGELPLIISNALDVDIGFLALYRYTDLNYTVLKNISDFVLRKYNTPV
                     KEYILSRQFYKADHEWKKIRYYTMEDMNEKPAIPENSEYQVLDIFDDTKIEKEILKILE
                     ELANNIFVI"
     CDS             6303..6539
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MEELIKNVILKYTMIKVENSEQNLLDLPVVEECWIYVIMELENTY
                     NLPIIKLLDDIKVDEFNLQTICDKLNHIRKVAF"
     CDS             7003..8523
                     /locus_tag="ctg42_8"
                     /transl_table=11
                     /translation="MKKSVLAIMVGALCIILSSCQETPEESSVVSKVDGISEAAVCEPL
                     KKGEKRETNVPTHWKFEEKKSNDRVVIQADIKLGEQSIGNLPVIEMQNHELTQEELNGL
                     IDYFTDGEELYMPQMVTKDAYQEVLDRISSKEGSYLQSAYSTSIAGIQNATREGMELAP
                     DEASAPEKMEIKFQKKTEDHGVEAARSWMSTELENTDTEDYFTADVGEDRKAYIEAERY
                     NQEIDNDSSFLWMEGSNFIEEETIETEEMQSEYYSSFGMDTNGYTEKFHELADAYRKCM
                     DKITFTEEDGKEQAEQVLEDLGIDGMGLVDSDRTVWFPNGACSERNGLGLGSDALWQGD
                     LDRGLPGYLYCFSKSVEGITSVPDGVVAEETVDSYVPPFQVETISILITEEGIKYFKWD
                     GISEEVCTVTENTKLLPFEKIQAKLTDQIFYWYSGKGQSANDTTALEYDVVNAKLQYTY
                     TTAYQEPKHAWLVPAWIFTVRESIGGNSLQELSYVINAYDGSVIGEAY"
     CDS             8633..9733
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 53.9; E-value: 2.9e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_9"
                     /transl_table=11
                     /translation="MQMIKLALIDNGIPYHMRNNRNQRIVHKSFLASKCDPSEYKDDKS
                     FHGAVCVGIITSICSDIELWDLNVTDSAGTTQITVLLEALEWCIQNKIKLIHMSLGTIN
                     YFDIKPLWIQIKRLLDADAIIVAAYHNRNIKTYPAAYPGVFGVRQDRYGLLGNGQILFQ
                     EQKGYNIENSIIANFSWNGIVNQANSYAAPVVTGHIATYLNRKPTAGFDDVMDFLMTIA
                     THKSDYPDILENVIRDKTNIEIPVIAGIDLDYEEMIQLKVMFSQNGYYAINLQKNPLDE
                     NVIPLEYYDDSNESLNDILYTVYIAYEPDIILLNQEEEIFESSKASDIDMYIVRKNNMY
                     ELYAEDRIGITYNIEDIYELVCQYFA"
     CDS             9753..11438
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 239.1; E-value:
                     1.6e-72)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_10"
                     /transl_table=11
                     /translation="MDMRENGKTWYRICKMLCEYKKYFPGIICCLLGSSFITFIHPLLI
                     RQITDCGILQKNMKYILLFSVILIIISLTQQELNIIQTKLFSNVHNQFTHSLYKKTYWK
                     INRMKIQYFAERGSAEIINTIGMDIDNVSSVVDQITQFSISSILQIIGGVVGLSLLDWK
                     LAILIEAIIPLKFIIVSYCANKKREVFEQWIEDKRKFMSWFAECINGIHEMKLWNLFQV
                     KKSQFEGLQKDLMDSYKKNAMLDEYSTVSVVVIDTVVNALLYILSGLFIIKGEFTIGGA
                     FAFITYSAYVVNPISALINIKYYFAQIEPSAKRLFELWGQPEELEMKLCEMKPEKIYQD
                     RDMVFEVKNLVFGYEPGHPILNGISLCVKKGERIAIVGENGSGKSTLLNLLAGFYRPQK
                     GIIKLYGAPVELMDIQDMRNRIAVISQRPYLFQGTIEENVNIDGKASRDAVVEACRKSG
                     ALGFIEKLDHGFGQKIGQDGAKLSGGERQKIAVARALLKNADILLMDEATEGFDVESNE
                     ALRELLHSELKNKTIVFITHKYKELESVDKVYRLSKGILELVRS"
     CDS             11512..11658
                     /locus_tag="ctg42_11"
                     /transl_table=11
                     /translation="MIVMYRRLNKQRSIFTSSQALMKAIYLDYKKFEIGGAKSVKKRKV
                     ILM"
     CDS             complement(11775..14084)
                     /locus_tag="ctg42_12"
                     /transl_table=11
                     /translation="MERCDFSSISTCLKNQISESNQMNQPDFLYELFEDFMNDPINEDF
                     SMDNGLICRWITGQAKISPKITSYYAKPSNQKKLATTIQRNLLPLMADCNMVIQDIYTL
                     FIQDDTISDTKKQELVSLYKPSDSRLLFLAKVLSFGMERQFIKRDTRNQKLIAGGVLSP
                     IVLDYIMDSEVPKPCRHFLGREEELDELHTLFEENRHIFLYGIAGIGKSELAKAYAKQY
                     RKQYTNILYMEYTGNLYQDIVDMDFIDDPPEISEQERFQRHNRFLRSLKSDTLLIIDNF
                     NVTSTQDSCLSVVLKYRCRVLFTTRSQLSEYCSFQLKELKDIPTLFQLTSVFYSEAEEN
                     RAIVEKIIETVHYHTFAVELAAKLLENGILTPEQLLIKLQEEKASLHNEDKIKVMKDGQ
                     SKKATYYNHIHTLFSLYSLSRKQQDIMCNMCFMPSSGISARIFSKWLELPTLNDVNDLI
                     ETGFVQSSLRHTISLHPMIQEIAVSETAPSVTSCHTLLDSLQKICLMHGIEVSYYKKLF
                     QTVENIMLFIEKDDIPQYLLFLEDVFPYMEKYHYQKGMKKIIQELQHFIKANTYGTASD
                     RALLLDYQATLEPKTEKAIKLEKEALAQIKETTKENAHLVSNLHSNLGGLYRINGQLDL
                     AKRHMKMGISLLQQYQLLYTNDSIPQINNYAVLLIEIQEPDLALSALQKLAQIIKEYNS
                     NHCLDYAQVQESLGSICLITANISQAKTHFKKALKIYEDIWADEPELIEEKYQAIQELY
                     PQAGIALAKSILLTKH"
     CDS             14341..14529
                     /locus_tag="ctg42_13"
                     /transl_table=11
                     /translation="MLKEAYSMNTLFDSVEVLDTKKEIQKENVSYEHAGYQIRVHFNGE
                     KTLIQCIQNLTERKIAG"
ORIGIN
        1 ttaaatcgca ggtttgtgtt gcggatatgg ttctgcatgg cttatcccct ccttttcagg
       61 ctcatataag ccagagattc ataacctttg gcagtggcac agatatcatc aaggatggta
      121 actcgtgatt tgtcatacgc tccaaagtta cggatcaggc atccaccgcc tccgaccaca
      181 tacaggcgca tcaggccagg attgtattca tatttgcgga gcgtggcaaa aatatctgtg
      241 acatactgtc tggcaacagc agtaatacaa tccagataag acgctgaaat gtcagcggtt
      301 ccaaaccgca gaatctgctc tacggtagat tcttcaatct ttactccgaa gttgtccaga
      361 acagcgtttt tagcggcaat catgcattgg tttacgccaa acttttctgt ccagcaccgg
      421 ctttcctgtg ctttcttatt attgatatac agaatgttca tggttccgtt gccgatatct
      481 gcaagaagat ttgtcccctt gaaatctcca agtcggttta cgatagccgg atatccctgc
      541 gggtaaaggc tgcatcccac aaaacggaga tgatactctt tgctgttaaa tcggtaatgg
      601 acttctggat tctggagcag ataggaacgg aaatcttctc tctggtttct gatccatgtc
      661 agaggaagcc cggcagccag atgaacgtct gcttcacgga tggaaaagac attcagttcc
      721 cttgcaatcg ccatgagagt tagaagataa tattcttcgt ccatagcttt atctgggata
      781 aattctttgt gtccttcgcc aatccggtag taaatgccgt tatattccag aatattcccg
      841 gtgaagatgg gttctgtttc ataggctttg attccggttg gtgtgacggt atttgctgtt
      901 ttcatgttgc cgtagccgtg atctacagca atgatttttg tgtttctgag ttctcgcata
      961 aaaaacacct ccattttcgt attgattaat tcagcaggct gtaccggtgt ggtactgctt
     1021 tgctgtgaga taagcatacg aaagttggag gaaaaagaca ttgagggaaa attgagttgg
     1081 aattgaaaaa taggatataa ttttgtaaaa tagagcaatt tctttagttt tttatagccc
     1141 tgcatttttt tgttataaac gttcattaaa tgttgacatg ttattatata aatagtaaaa
     1201 ttgtacaata aaatgtggaa agttggatgg aatttattga attataataa aactaatcgt
     1261 acttaactgg cggcttatgt atttgtagaa cttagaataa tagaaaattt aaaatattat
     1321 caatttttac agctgttgca atgctttcag taggaacaac agtttttgca agtccttaac
     1381 tgttgtttga taaggagtgt agttttatac aaatagtgat attattgcaa aaaactagga
     1441 ttttataaaa ataaaaaaat caagtctata gctgtttgaa gtgaggagaa aagcgtatga
     1501 gaaatgtgtt ggcaacggac ataaaaaaca atattcgaag cattcgcttt attttgggga
     1561 tttttctaat cgtttcggct accctgatgt ctgagcatga gatgttgcag aagatcataa
     1621 atgcaggcgg atctgcagaa ggaccaggct ggttcgtagc atacacctat tgtatgaaca
     1681 gcgttaatat gcttctgttt gttcccattg ccgttgcttt tgcgggtgga gagaatacgg
     1741 aggctgagct gcacagtcgt ttttttctgt tcagttatat ccgttcaggg agaaaacagt
     1801 atctcgtagg aaaagcagca ggattgttgg tctccggagg tttgacagct tttttagcca
     1861 tggtgttcct tcttgtaatc tgtatactga ggttcggtca gtatccttct ctgattgacg
     1921 gaaattatga gatggcagtg cttgtgggca gaacggcggt aagctttctg agattgtttt
     1981 taaatggcgc tttttgggcg ctaattggcg gtacgtcggc tgtcataaca aaaaatcgct
     2041 atatgtccta tgccgttcct tttattcttt attatgtcct gaccgtattt caggagcgtt
     2101 actatcaaaa agcattcttt ctgagtcccc gctattgggc ggcgtctatt tactacaatg
     2161 atatcttctg cattgctata ttagcggttg gaagtttttt aacggcactg atctttatgt
     2221 gcgcaataga aagaaggttg cggtatgcgt gatattaaac aggctttttg gattgcaggc
     2281 cagaatttct atggatggaa aaaaagtccg aggatctgga tgacctttat tttggcagct
     2341 atattatgtc tgatgctgtc ggatcagatt atttcccatg cgataaaata tgagacaatc
     2401 cttcaggtat tcgagccgtt tatttggaca tatggggatg catcctctgt tatgctgtcc
     2461 tccctgcttt taatcctgct ctttgcggac atgccattta tcagtcaggc aactccgtat
     2521 tggcttgtac gcacaaaacg gaagatatgg cttgcgggtc agattatcta tgtgatcctg
     2581 gcgactgtga tctataatat ttttttggct gtgatgcttg gaattatggg agctcccttt
     2641 tcctttacgg gaaatgtgtg gagcgaaaca gcggcaatgt tgggctatgg cggtggggag
     2701 agcataaccg ttcctgtttc cataaaaaca atggaaagct caactcctta tatgtgcgca
     2761 gcaatagtgt ttggacttgt acttttatat actcttttta tcgcagttct catgttgttt
     2821 ttaaatctgg ctgcgggaaa tatggcaggg gtgatcggtg cttttgcagt cagtctgtat
     2881 gggctcctgc tgaacccaga tgttttccgg aaactgtttc attttacaga aagtcaggaa
     2941 tatagggcga acgtgttctg cggctggctg tctccgttga accaagctac ctttcccatg
     3001 cacagctttg gttatgatta cctgccaggg atcgggatga gcatgttcat atttgcaata
     3061 ttaatcatag cgctgatcgg cttgtcagcc gtccgaatta agggctataa tttctctttt
     3121 acgcagacaa acgaataaat ggagggcaaa atggaatatg caatcaggtt gaagggactg
     3181 acaaaatcct ttcaaaaaga aaaagtatta aagaacatta cccatgattt tgaaaaaggg
     3241 aagattcatg ggattatggg gtttaacggt tcagggaaaa ccgtaatgtt taaatgcatc
     3301 tgtggatttt tacaacctga gagcggcaca gtgctcgtag ggggaaaaca gatcgggaag
     3361 gagctggact ttccagattc cgtaggcatt atcattgaaa accctggctt ctttctggat
     3421 ctcagcggtt ttgcgaattt aaagagactg gcgtctctga aacaccgtat ttccgatgac
     3481 gatgtgaggg cgacgatgcg tgccctaggg cttgatcctc tgtctaaaaa gaaggtagga
     3541 cagtattctc ttggaatgcg tgaacgtctt ggtatcgcac aggcaatcat ggaagatccg
     3601 gagcttttga tattggacga gccttttaat ggtctggaca agcagggggc aggagaggtc
     3661 tgcgagcttt tgcggggatt aaaggaacga gggaagacta ttcttatcgc agcacataac
     3721 atgctggaga tcgaatggct ctgcgatacg atctgtgaga tggatgcagg tgtcctgacg
     3781 cagataaaat aaaaatacgg gggaaagaat atgggaaagg tattaattaa atgcattcaa
     3841 acaccaatgc agaaatattt ttatgatcgt tctttggatt ctgtagttat ggtgaatgat
     3901 gaagaatatc agatattaaa aactgtggaa aagacaaaat tggttcctga tggagtgtta
     3961 agacggtttg tgaaaagcgg attattgcgt gagactgcga tagaagaaat tgagcatcct
     4021 gagacagaaa acttacattt gttggcagaa cattatatgg gcaatctgat tttgcaggta
     4081 actcagcagt gtaatttgag atgcaaatat tgtgcatatt ctggaaacta ctataatcgt
     4141 tcccatacgt caaataggat ggatttcgag acagccaaaa aagcaataga cttttatttg
     4201 aaaagaagcg aaaaagcgga tcaacttgca ttatcatttt atgggggtga gcctcttctg
     4261 gaatttgaat tgattaagaa atgtgtttcc tatattttac aacgtaaagg ggataaaaaa
     4321 attcttttta ctatgacgac taatgggact ttaatgacag aagatgtcat agaatttttg
     4381 gtaaaatatg agtttaatct tatgattagc cttgatggtg ataagaaaag tcacgatata
     4441 aatcgaagat ttaaaacagg aaaaggttca tttgacatta ttttagaaaa tttgagtaga
     4501 ctgaaagctt acaatgaaga gtactattca aaagttttgt ttaattgtgt tattagttct
     4561 tcatcagatc ttgaaaatat atatcgattt tattcggaag aagagctgtt tgaagcaggg
     4621 acagtgaatt tcaattatgt aaatccagtt ggtttaaaag atgagacatt gtcgcgcata
     4681 acacaaaaaa atttcagagt acatcgacta gcatatataa agatgatttt atctgtatta
     4741 gagaagcgaa aatgggatgc acaaagtcga ttgttgcgaa gagaactgca agatattgag
     4801 ttattatatg aacagctaca tagtcatgtt gctgaaggca aaaaaacaca tcatggtggt
     4861 ccatgcattc ctgcagttag aagactattt gtggatacaa aaggtgaatt ttttccatgt
     4921 gaaagagttt cggaagaaga ttcagaaatg tgcatcggaa gtttggattc gggatttgat
     4981 tttgataaaa tgagtttcct acttaaccat ggtaagatga ttaaagaaaa atgtttagga
     5041 tgttggaatt tgagaatgtg tgcatattgt ttggtgcaaa ttccaaaaga taatcagata
     5101 ttaacagaaa atatgttgct acagcaatgt gaaaactcaa aagaaagtac acttttattg
     5161 ctatataaat tgtgtatact tgttgagttt ggatataaag gaaatgaaaa tttgcaagta
     5221 ttaaaataaa ggagtgcata tggaaaaatt agttgtgttt ccattaaata atgacacaga
     5281 aatacttatc aagggattga aagaaaacaa attatatcag gtggttgcgg tatccagcta
     5341 tatagaagat aggagtaggc ttgaactatt acaaaagaag agttcgatat attgtagtac
     5401 agaatttgaa gaatgtctta ctcgagctga tgctattgtt ttttcagaaa atacaatggg
     5461 atatagttat gacggatacc aaaaaagagt gcaaatggca ttagactcag ggaaaaagat
     5521 ttatgctggt ttagcactgc tagataagat tcaaattgac agagataaag tatgtatatt
     5581 acaggaaagt gaattgtcag atgaagttgt ttcgccaaat aaaaaagaaa tagatattcc
     5641 ggtaatatca gtcatgggat tgggcgaaaa ttgcgataaa ttccaattgc aagtgaagat
     5701 taaaaaggtg attgaaaaac aggggtatcg tgtactggca ctttgctcta acgttctcgg
     5761 tggattttta ggaatggaaa atcttcctgg ctttctatat tcaaaattca tgtcttatcc
     5821 agaaaagatt attgctttaa atcattggat acatacaaaa gtaaaacaac aggagtacga
     5881 tgtgattctt gtgggttgcc ctggtggtgt ttcggaattt gaaaaatatg aaacaaatta
     5941 ttttggcgag ttacctctga ttatttcaaa cgcattggat gtagatatag gctttttggc
     6001 tttgtatagg tatactgatt tgaattatac tgtattaaaa aatataagcg attttgttct
     6061 aagaaaatat aatacaccag tgaaagaata tattctttca cgacaatttt ataaggcgga
     6121 tcatgaatgg aaaaagatac ggtattatac catggaggat atgaatgaaa aaccagcgat
     6181 acctgaaaat tctgaatatc aagtccttga tatatttgat gatactaaaa ttgaaaaaga
     6241 aattttgaaa attttggaag aacttgcaaa taatattttt gtaatataag tgaggagata
     6301 ggatggaaga gctaattaaa aatgtgatat tgaaatacac aatgataaaa gtagaaaatt
     6361 cagaacagaa tctattggat ttgcctgtag tagaagagtg ctggatatat gtgataatgg
     6421 aattagagaa tacatataat ttgccgatta taaaattgct ggatgatata aaagtggatg
     6481 agtttaattt gcaaacaata tgcgataaat taaatcacat acgaaaagta gcattttgaa
     6541 ttagtttatt ctatatccgg aaattataat atgaaatatc atatatctgt ttctcttggc
     6601 accaatgaag cggaaatatt gatattattt taacagaaag gaggagaacc gtatgaagaa
     6661 actcaacaaa aatatgaaga aaaacaggaa cacgattgag tcttttgggt gcgtttgtgg
     6721 atgtggttgc ccatgttcat attgtgctgc gacttggtta tctcagcata atgcggatgc
     6781 ttcaagagtg gttattagta atgacaatag cgtaatgtac taacaagtta tagttactag
     6841 tacatagaac agactgcctt atacattaaa ataaataagg tagtctgttt ctaaaaaata
     6901 tacgaaaacg ttaatagtgt caggaaggta tttataagtt aaagagttta taattgaagt
     6961 ttcgtgaaaa agcgacaatt ctataagata tatggaggaa aaatgaaaaa aagtgttcta
     7021 gcaattatgg taggtgcgtt gtgtattatt ctttccagct gtcaggaaac accagaggag
     7081 agttcggtag tcagcaaagt ggatgggatt agcgaggcgg ctgtctgtga acctcttaaa
     7141 aaaggagaaa agagagagac aaatgttcca acgcattgga aatttgaaga aaagaaaagc
     7201 aacgaccgtg tggttatcca ggcagatatt aagttgggcg aacaaagcat tggcaatctt
     7261 ccagtcatag agatgcaaaa tcacgagtta acgcaggaag aactgaatgg attgattgat
     7321 tattttacgg acggtgagga actatatatg ccacagatgg tgacaaagga tgcgtatcag
     7381 gaagtgttag acaggatttc cagcaaggaa ggaagttact tgcaatcagc atattctaca
     7441 tcgattgcag ggattcaaaa cgcaacccga gaggggatgg agcttgcacc ggatgaagcg
     7501 tctgcaccgg aaaagatgga gataaaattt caaaaaaaaa cagaggatca cggtgtggaa
     7561 gcggcacgga gttggatgag tactgaattg gaaaacacag atacagagga ttattttact
     7621 gcagatgtgg gcgaggacag gaaggcatat atagaagcag agcggtataa tcaggaaatt
     7681 gacaatgaca gtagttttct ctggatggag ggttctaatt ttatagaaga agaaacaata
     7741 gaaactgagg aaatgcagag tgagtattac agtagctttg gcatggatac caacggctat
     7801 acagagaaat ttcatgaact ggcagatgcg tatcgaaagt gcatggacaa gatcaccttt
     7861 acagaggaag atggaaagga acaggcagaa caagttttag aggatttagg tatcgatgga
     7921 atgggccttg tagattctga tcgtaccgtg tggttcccga atggcgcatg ttcagagcgc
     7981 aatggtctgg gacttggtag tgatgctttg tggcagggag atctggatag aggattaccg
     8041 ggatatctgt attgtttttc gaaaagtgta gagggtatta cttcagttcc tgatggcgtg
     8101 gttgcggaag aaacagtgga tagttatgtg cctccgttcc aggtagaaac aatctctatt
     8161 ctgataacag aggaaggaat taaatatttt aaatgggatg ggatatcgga agaagtctgt
     8221 acggtgacgg aaaatacaaa gcttctgcct tttgaaaaaa tacaggcaaa gctgacagat
     8281 cagatttttt attggtattc cggaaaaggc cagtctgcca acgacactac cgcactggag
     8341 tatgatgtgg taaacgcaaa attgcagtat acttatacca cagcctatca ggagccgaaa
     8401 cacgcatggt tggttccagc atggattttt actgtcaggg aaagtattgg tggaaattct
     8461 ctacaggagc tttcttatgt gatcaatgct tatgatggca gtgtgattgg agaagcatat
     8521 tagggttcag cgacacttga atttttattg accatagaat tacaaggttt atcatgagaa
     8581 taataaatat gcgatatttg gcttggatat ataacaggta agaataggaa tagtgcaaat
     8641 gattaagctc gcattgattg ataacggtat accttatcat atgagaaata acaggaatca
     8701 aaggattgtt cataaatctt ttttggcttc taaatgcgat ccaagtgagt ataaagacga
     8761 taaatcattc catggcgctg tatgcgtcgg aattatcaca agcatatgta gtgatataga
     8821 attatgggac ttgaatgtga ctgactctgc aggaacaaca cagatcacag ttttgctgga
     8881 agctttggaa tggtgtattc aaaataaaat aaagttaatt cacatgagtc ttggaacaat
     8941 caattatttt gatattaaac ccttatggat tcaaataaaa agattacttg atgctgatgc
     9001 gattatagta gcagcatatc ataacagaaa tataaagact tatccagctg catatccagg
     9061 tgtttttggt gtcaggcagg atcgttatgg tcttttggga aatggtcaaa ttctgtttca
     9121 agaacaaaaa ggttataata ttgagaattc tattatagca aatttttcgt ggaatgggat
     9181 cgtaaatcaa gccaatagtt atgcggctcc tgttgtcact ggacatattg ctacatattt
     9241 aaacagaaag cccacagcag gatttgatga tgttatggac tttttgatga ctatagcaac
     9301 gcataaatct gattatccgg atatactaga aaatgtaata agggataaaa ccaatataga
     9361 gataccggta attgccggta ttgatttaga ttacgaggaa atgatacagc taaaagtgat
     9421 gtttagtcag aacggttatt acgcaataaa tctgcagaaa aatcctttag atgaaaatgt
     9481 aattccttta gaatattatg acgattccaa tgagtcattg aacgatatcc tttatacagt
     9541 atatatagct tatgaacctg atattattct tttgaatcaa gaggaagaaa tatttgaaag
     9601 tagtaaggca tcagatatag atatgtatat tgtgcgtaaa aataatatgt atgaattgta
     9661 tgcagaagat cgaataggaa taacttacaa tatagaggat atatatgagc ttgtttgtca
     9721 atattttgct taacgaatag tgaggatggc aattggatat gagagaaaat gggaaaacat
     9781 ggtatcgaat ttgtaaaatg ttgtgtgaat ataaaaagta ttttccaggg attatctgtt
     9841 gccttttggg ttcatcattc ataacgttta tacacccact gcttataaga caaataacag
     9901 attgtggtat attgcagaaa aacatgaaat acattctttt attttctgtt atattaataa
     9961 taatttcttt aacccagcaa gagttaaata taatccaaac aaaattattt tcaaatgtac
    10021 ataatcagtt tacacattct ctctataaaa agacttactg gaaaatcaat aggatgaaaa
    10081 tacagtattt tgctgaaaga ggaagtgcag agattataaa tacaattggt atggatattg
    10141 ataatgtgtc atctgttgtg gatcagatta ctcagttttc tatatcatca attctccaaa
    10201 taataggagg agtagttggg ctgtccttat tagactggaa attagcaata ttgatagaag
    10261 caattattcc actgaaattt ataatagtgt cctattgtgc aaacaagaaa cgggaagtgt
    10321 ttgaacagtg gattgaggat aaacgaaagt ttatgagttg gtttgccgag tgtataaatg
    10381 gaattcatga aatgaagctc tggaatctgt ttcaggtaaa aaaatctcaa tttgaaggtc
    10441 tgcaaaaaga tttgatggat tcatataaaa agaacgcaat gctagatgaa tatagtactg
    10501 tcagtgttgt agtaatagac acggttgtaa atgcgttatt atatatatta agtgggcttt
    10561 ttataataaa aggagaattc actataggcg gagcatttgc ttttattaca tatagtgcat
    10621 atgttgtaaa tccaatttca gcattgataa acattaaata ttattttgcg caaattgagc
    10681 catcggcaaa acgtcttttt gagttatggg gacaaccgga agaattggaa atgaaattat
    10741 gtgaaatgaa acctgagaaa atttatcaag atagggatat ggtttttgaa gtaaaaaatc
    10801 ttgtctttgg ttatgaacca ggacacccta ttttaaatgg tatttcacta tgtgtaaaaa
    10861 aaggggaacg aattgcgatc gtaggagaaa atggaagtgg caaatcaaca cttttgaacc
    10921 ttttggcggg attctaccgg ccacaaaaag gaataataaa attgtatgga gctcctgtgg
    10981 aattgatgga tatacaagat atgagaaata gaattgcggt tataagccaa agaccatatc
    11041 tattccaagg gactatagag gagaatgtta atatcgatgg aaaggcgtca agagatgcag
    11101 ttgttgaagc atgtagaaaa agtggtgctt taggttttat tgaaaaattg gatcatggat
    11161 ttggacaaaa aattggacaa gatggtgcaa aactttctgg aggagaaaga caaaagatag
    11221 ctgtagctag ggctctgctg aaaaatgcag acattttact tatggatgag gctacagaag
    11281 gatttgatgt tgaatcaaat gaagctttac gtgagttatt acatagtgaa ttaaaaaata
    11341 agactatcgt ttttattacg cataagtata aagaactgga aagtgttgat aaagtatatc
    11401 gcctttcaaa aggaatttta gaattggtgc ggagttagag atataaattt ctaatagaac
    11461 tgagccacta tgcatttgac atattgtatc aaacagtagg ttgatgacga gatgattgta
    11521 atgtatcgca gattgaacaa gcagaggagc atatttacaa gttctcaggc attgatgaag
    11581 gcaatatacc tagactataa aaaatttgag ataggaggag cgaaaagtgt caaaaaaaga
    11641 aaagtgatcc ttatgtaaac gctccatgtc taagaaaaaa tggaaatgga caagcgccta
    11701 gtcttggagt gtatctcaaa actaggcgtt tacattattg aggcaatata ttttacaagt
    11761 gtttgtagga accgttagtg cttggtgaga agaatacttt ttgccagagc aattccagct
    11821 tgtggataca attcttgaat tgcttgatat ttttcttcaa tcaattcggg ttcgtctgcc
    11881 catatatcct cataaatttt caaggctttt ttaaaatggg ttttcgcttg cgaaatattt
    11941 gcagtgatca ggcagatact tccaagggat tcctgtacct gggcataatc caaacagtgg
    12001 tttgaattat attctttgat aatctgtgct aatttctgaa gagcagacag ggcaaggtca
    12061 ggttcttgta tttcaattaa gaggacagca taattattaa tctgaggaat actgtcatta
    12121 gtataaagaa gctggtattg ttgtaaaaga gagataccca ttttcatgtg ccttttagcg
    12181 agatcaagtt gtccgttgat tcggtaaagc cctccaagat tggaatggag gttggaaacc
    12241 aggtgggcat tttcttttgt ggtttctttt atttgagcaa gtgcttcttt ttctaatttt
    12301 atcgcttttt ctgttttggg ttccagagtt gcctgataat ccaatagtaa ggcacggtca
    12361 gatgcagtcc cgtaagtatt tgcttttata aaatgctgta gttcctggat gatttttttc
    12421 ataccctttt gatagtggta cttctccata tatggaaaaa catcttctaa aaataacagg
    12481 tattggggaa tatcgtcctt ttcaatgaaa agcatgatgt tttctactgt ttgaaataat
    12541 tttttataat agctaacttc aatgccatgc atcaaacata ttttttgcag agaatccaat
    12601 aacgtgtggc agcttgtaac agaaggtgcg gtctcggaaa ctgcaatttc ctgaatcatt
    12661 ggatgcagag aaatagtatg ccggagactt gactgtacaa aacctgtctc gatcagatca
    12721 ttcacgtcat ttaaagtagg cagctccagc catttggaaa atatacgggc agaaatacca
    12781 gatgaaggca taaaacacat attgcacata atatcctgct gtttccgtga taaggagtat
    12841 aacgaaaaca gggtatggat atggttgtaa taggtggctt ttttgctctg accatctttc
    12901 attactttaa tcttatcttc attatgaaga gaagcctttt cctcttgaag ttttatcaat
    12961 aattgctctg gagttaaaat tccattttcc agaagtttgg ctgccagttc gacagcaaaa
    13021 gtatggtagt gtacagtttc tatgattttt tctacgattg cccggttttc ctctgcttct
    13081 gaataaaata cagatgtcag ttgaaaaaga gtgggtatat ctttcagttc ttttaattga
    13141 aaactacagt attcagacag ttggcttctg gttgtaaata aaacccggca acggtatttt
    13201 aatacgactg acaggcaact gtcctgtgtg gatgtgacat taaaattgtc tatgatcagc
    13261 agtgtatcag atttcaaaga gcgtaagaaa cggttatgtc tttgaaaacg ttcctgctca
    13321 ctgatttctg gtggatcatc aataaaatcc atgtctacaa tatcttgata tagattaccg
    13381 gtgtattcca tatagagaat attggtgtac tgttttctgt attgctttgc ataggcttta
    13441 gcaagctcgc tttttccaat tccggcaatt ccataaagaa atatatgtcg gttctcttca
    13501 aacaaagtat ggagttcatc cagttcttct tctcttccta gaaaatgacg gcatggtttt
    13561 gggacttcgc tgtccataat gtaatccaga acaatcggag atagaacacc tcctgcaatc
    13621 agtttttgat ttcttgtatc acgtttaata aattgccgtt ccataccaaa agaaagtact
    13681 tttgctaaaa acaacagcct tgaatcagaa ggtttatata gagatacaag ttcctgcttt
    13741 tttgtatccg aaatcgtatc gtcctgtatg aataacgtgt aaatgtcctg tataaccatg
    13801 ttgcagtctg ccattaaggg aagtaagttc cgctgaatgg ttgttgccag ttttttctga
    13861 ttgctgggtt ttgcataata tgaggttatt ttgggactga tttttgcttg tccggttatc
    13921 cagcggcaaa ttagaccatt atccatagaa aaatcttcat ttatcggatc attcataaaa
    13981 tcttcaaata attcgtataa aaaatcaggt tggttcatct gattgctttc actgatttga
    14041 ttttttaggc atgtgctaat agaagaaaaa tcacatcgtt ccaacagaaa tccctccttt
    14101 ggttttcgtg ttttatattc ttaaagtctt tttattataa cacgaacaaa tgttccggac
    14161 aataggaatt gatactgtat aggaagaaaa tgaatcttaa aaactcaatc tgcggtcaat
    14221 ttcaattcaa tgtgattggt gcagaataat tttagaatgt aatcaggctt tcgaaagccg
    14281 aattcaattc atacagaact tttgtacaat cctgccggca taggatgtag agagaactgt
    14341 atgctgaagg aggcatatag catgaatacg ttatttgatt ctgtagaagt tctggataca
    14401 aaaaaagaaa tccaaaaaga gaatgtaagc tatgaacatg caggatatca gattcgagtg
    14461 cattttaatg gggaaaagac attgatccag tgcattcaga atcttactga acgaaaaatt
    14521 gcaggttgat tttcttaagt tcttgttgta aaataaagac aattaaagac aatgactacg
    14581 caagaccgat gaaaagaggg atagaatgta tcaggcagga atttattgcc gaatttccat
    14641 tgaagagcaa aataaagagg gtgaatacag caatagtatt cactctcaga ttcagatggc
    14701 aagagattat attgcagaga ataaagatat tgcagagaaa aaagtttatg tagacgatgg
    14761 ggcttctgga agtaattttg aaagaactga atttcggagg atgctggcag atattgagct
    14821 tggtgttatc aatatggtga tttttaagga cgtatctcga cttggaagag aacatattga
    14881 taccaactat tatctaggca aatatttccc ggagaaacag attcggattg tttcgattct
    14941 ggataattat gattcagccg ttggaactta tgatgaaatg ttagaaataa aaactttgct
    15001 gaatgatatg tatttgagag atacatccag aaagattaag acaacgattc agaccaaaag
    15061 aagtatgggc gaatatactc cgaaacagcc cccctttgga tatgtgaaaa gtaaaacaat
    15121 tcataatcat ctggaaattg atccttatgc agccgaggtt gttcgaagaa tttacagaat
    15181 gtatcaaaat ggatttggct gtacggttat ttgcaggact ttgaatgaa
//
