LOCUS       c00020_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGDIBNIP_104.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:27:51
            Original ID  :: gnl|Prokka|CGDIBNIP_104
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 23859
            Orig. end    :: 47108
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[33859:37108]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1575..3032
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_24"
                     /sec_met_domain="FGGY_C (E-value: 3.2e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 2e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3144..4079)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg20_25"
                     /sec_met_domain="LysR_substrate (E-value: 1.4e-33,
                     bitscore: 107.6, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.7e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLRNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFERYIYQKEQ
                     LLLAVPKNYSVNTRLQKYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4195..5619
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_26"
                     /sec_met_domain="Lyase_1 (E-value: 1.1e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.1e-22, bitscore:
                     70.1, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPI
                     HMTEPGISGKDYLIKK"
     CDS             complement(5728..7413)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_27"
                     /sec_met_domain="FTHFS (E-value: 2.7e-275, bitscore: 905.3,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGRTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_28"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2e-13, bitscore:
                     42.4, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.6e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQTAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEYLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_29"
                     /sec_met_domain="Spermine_synth (E-value: 1.5e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.2e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_30"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.8e-43, bitscore:
                     141.1, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.2e-35,
                     bitscore: 114.2, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKK
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRIRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_31"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 9.1e-15,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKDVCTRASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDGECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_32"
                     /sec_met_domain="PAD_porph (E-value: 2.6e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGDFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTQED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15406
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_33"
                     /sec_met_domain="CN_hydrolase (E-value: 1.6e-56, bitscore:
                     183.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGVYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALNFYGSSFITDNTGALCAELPRGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKISGMNFGSVTENGVNSN"
     CDS             15551..16012
                     /locus_tag="ctg20_34"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGSTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16216..20913
                     /locus_tag="ctg20_35"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFILQAILGLVPVCVTQAAPLTVETWD
                     SDKVVEYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAAASKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQFLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARPVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMLSFLCTVTEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLKVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEMVFKTESTEPEKIVNTAKA
                     RGDISPEITAQQEAYVKAKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGSGGSSYANSGGYGSYQGGSMAGSS
                     KTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20910..21797
                     /locus_tag="ctg20_36"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSQ
                     MAGVKNREGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSKS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             21989..23080
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_37"
                     /sec_met_domain="Peripla_BP_3 (E-value: 2.6e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCKKIL"
ORIGIN
        1 gttttccgat tcagctttct gagaagagac gtgcagcaat caaggaaact tataaaggtg
       61 aactttatga atgtcctgta actgttgaga atgaaaagga tatggagaaa gctcttgaag
      121 atgtaaacaa agcagagtgt aatgcgctgg ttgttttcct tggaaacttc ggacctgaaa
      181 ctcctgaaac tttgatcgca gagagatttg acggaccttg tatgtatgta gcagcagcag
      241 aaggtgacgg tgatatgatc aacggcagag gtgatgctta ctgtggtatg cttaactgct
      301 cctacaactt aaaaatgcgt catctgaaag catatattcc ggaataccct gttggaacag
      361 cagatgatat tgcaaagatg atcgctgatt tcgtaccggt tgcacgtgca gtcatcggtg
      421 tcagcaatct taagatcatt actttcggac cacgtccaca ggacttcttc gcatgcaacg
      481 cacctattaa aggcctctat gagctgggtg ttgagattga agagaactca gagcttgatc
      541 ttcttgtttc tttcaaagag catgaaaatg atcctcgtat cccggaagtt tgtgcagata
      601 tggcaaaaga gatgggcgaa ggcaaatatt atgctgacct taatgtgaaa atggcacagt
      661 ttgagcttac acttcttgac tgggcagagg ctcataaggg agcaagaaaa tacgttgcat
      721 ttgctgacaa atgctggcct gcattcccgt cacagtttgg atttgaacct tgctatgtaa
      781 atagccgtct ggcttccaga ggaattccgg tatcctgtga ggttgatatc tacggagcac
      841 tcagcgagta catcggactt tgcatttcca atgatgcagt tacactgctt gatatcaaca
      901 actctgttcc acagtatatc tatgatgaag atattaaagg aaaatacgat tataagctta
      961 ctgatacatt tatgggattc cattgtggaa atactcctgc atgcaagatg tgtgattcca
     1021 gagctgttaa atatcagctg atccagcaca gacttcttga gccggcagga tctgaaccag
     1081 atttcacaag aggaactctt gaaggtgata tcgctgcatc tgacattaca ttctatcgtt
     1141 tacagtgcaa ttccgagggc gagctggttt cttatgttgc agaaggtgaa gtactggatg
     1201 tacctacaag atcattcggt ggtatcggta ttttcgcaat caaagaaatg ggaagattct
     1261 accgtcacgt actgatcgag ggcaactatc cgcatcatgg agcagttatg tttggacatt
     1321 acggaaaagc attctatgag gtagtgaaat tccttggact ggatgttaag aagattggat
     1381 ataaccagcc ggcaggcgta agatacccga cagaaaatcc atggggttaa tgagaaatca
     1441 gtaaaacgga ttattaatgt tcatgtgaag tgaatgaatc tgaatacaga ataaataaac
     1501 tgacactata ttaaaggcat cccggggctt tgctctggga tgtattagat tagaaataga
     1561 aaaggagagc acttatgtat tatattggta ttgaccttgg tacttccgct gtaaaacttc
     1621 ttcttatgga agaatcagga aaaatctgta acatcgtatc cagagaatat cctttattct
     1681 tcccacatcc gggctggtct gagcagaaac cggaagactg gtttgcgcag agtatggaag
     1741 gcatgaaaga gctgacaaag gatatcgaca gagctcaggt agcaggaatt ggttttggcg
     1801 gccagatgca tggtctggta acacttgaca aggatgataa tgtgatccgt cctgcaatcc
     1861 tctggaatga cggacgtaca ggtgaagaga cagaatatct gaatacagtg atcggaaaag
     1921 acaaactttc acagtataca gcaaatattg ctttcgcagg ctttactgca ccgaagatcc
     1981 tctggatgca gaaaaacgag cctgagaact ttaagaaggt agtaaagatc atgcttccta
     2041 aggattatct ggcatatcgt ctgtccggtt ctttttgtac agatgtttct gatgcttccg
     2101 gtatgcttct tcttgatgtg aagaaccgct gctggtcaaa agaaatgctg gagatctgtg
     2161 gaatcacaga agagcagctt ccgaaactgt atgagagttg ggaagtagta ggaactctga
     2221 aacctgagat tgcgaaagaa cttggattca gtgagaatgt aaaagttgtt gcaggtgcag
     2281 gtgacaatgc ggcagctgct gtaggaacag gtacagttgg tgacggtcag tgtaatattt
     2341 ctcttggaac atccggaact gtgtttattt ccagtaaaaa ctttggtgtg gacgaaaata
     2401 acgcacttca ttctttctgt catgcagatg gaagctatca tctgatggga tgcatgctca
     2461 gcgcagcttc ctgtaacaaa tggtgggcag aggagattct tcagacaaag gatttcgcag
     2521 cagagcaggc tccaattcag aagctgggag agaatcatgt attcttcctt ccatatctga
     2581 tgggagaacg ttcacctcat aataatcctg atgcaagagg tgtattcttc ggaatgtcca
     2641 tggacagcac aagagcagac atgacacagg ctgttctgga aggtgttgcc tttggtcttc
     2701 gtgattccct ggaagttgca agaaaccttg gaatcaagat tgagagaacc aagatctgcg
     2761 gtggtggagc taagagccca ctgtggaaga agatcattgc aaacgttatg aacctgaagg
     2821 ttgatgttct ggagaacgaa gaaggaccgt ccatgggtgg agctatgctg gcagcagtag
     2881 gctgtggtgc ttacccggat gtagaaacca tcggtaagaa atttgccaaa gttgttgata
     2941 cggtagaacc ggatcctgaa ctggttgcaa aatatgaaga gagatatcag aagttcagaa
     3001 ctctgtatcc ggcgatgaag ccattgttct aatcgaatat ctgcctgaca tactggggtt
     3061 gttgtgctta tttagcacaa caaccccatt ttgacgtaca tctgatgatg accaatcacc
     3121 acagcctatt tgattatgac atatcaggaa aagggcagct tcaggaattc ttccatggct
     3181 ctgctgatat agcggccttt cttccagtaa aaaaacacag tgcgtttact gctctgaccg
     3241 ggcagcttat aaaaaacaag ttctgaattt gttggaactc tggagagcag aagatccccg
     3301 atgaaagtga tacccattcc caaacatgca atattatagg cagtcatctg ctgatctagg
     3361 cgaaatacta cagaaggcga aaagtgattt tcctgacaaa tggtaagtgc acgcttaccg
     3421 gtatcattat ctgaacgaag aataataaat ggttcgttct cgaatttgtt taatggaaca
     3481 gaaggaatat gagaagaacg gaactgcccg ttccggattt cctcaatagg aatctgatat
     3541 ttctgcagtc tggtatttac tgaataattt ttgggaactg caagaagaag ttgttctttc
     3601 tggtagatat aacgttcaaa aatctggtta tccagaatac agttatcaat caccagatct
     3661 aactttccgg cctggagaaa ctgggatagt tttgctgtac tttcttctac aagagaaatt
     3721 tgaacatggg ggaatttttg ggaaaaatca gcaataaggg gaggcagaat ccacgaagaa
     3781 aaaaagttac tgccacctac attaagagtt cctgttttga gatttctcag atccagtagg
     3841 tagttttcga gattattttc aatatccatg actttttcaa cagcctgtat ataatgtttt
     3901 ccaacttcag ttaactgcaa aggtttggta cttcgatcaa aaataggata gccaatacgg
     3961 ttttccacac gttttacatt ggcgcttaaa gaaggctgcg aaatgaaaag agcagcagca
     4021 gctttggaaa agcttttttc cttgtagacc tcatagatgt attccattcc ctgaaacata
     4081 taaactcctc cgatatataa tttaaacact atatatttta taaaaatata tgtatttgat
     4141 tatattatag cagagatata taatgagggc aaatacatgg gagggcgaat aactatgaaa
     4201 aaaacagact atcgtgtaga aagggattct attggtgtaa aggatattcc ggaagatgta
     4261 tattatggag tacaatcctt acgtgcggct gaaaatttcc acattacggg gctgaatatg
     4321 catccggaaa ttattaacag tcttgcatac ataaaaaaag cagcagcgat aaccaattgt
     4381 gaggtggggc ttcttgagaa gaaaaaagca caggcgattg tccaggcatg tgatgaaatt
     4441 gtttcaggaa aattccataa tgaatttatt gtggatcctg ttcagggagg agctggcaca
     4501 tctttaaata tgaatgccaa tgaagtaatt gcaaatcgcg cgattgagat actgggagga
     4561 aaaaagggcg attatacaat tataaatcct aacgatgatg tgaattgtgg acagtctacc
     4621 aatgacgtga ttcctactgc cggtaaaatg acttctcttc gtttgttgca gaatctgaaa
     4681 aaacagcttc ttcgcctcta tgatgctctt aatgaaaaag ctacagagtt tgatcacata
     4741 ataaaaatgg ggcgtacaca gatgcaggat gcagtaccaa ttcgtctggg acaggaattt
     4801 aaggcatatt cggtagcaat catgcgtgat atccacagaa tggataaagc aatggatgaa
     4861 atgcggactc ttaatatggg aggtactgct attggaacag gaattaatgc agatgagggc
     4921 tatctgagaa gaattgttcc aaatctcact gaaatatcgg gaatggactt tatacaggct
     4981 tttgatctga ttgattccac tcagaatctg gatccatttg tagctgtttc cggtgctgtg
     5041 aaagcatgtg cggtaactct ttccaaaatg tcaaatgatc tccgtctgat gtcctccggt
     5101 ccacgtactg gttttgggga gattaatctt ccggcaaaac agaatggttc ctctattatg
     5161 ccaggtaaag ttaatccggt tattcctgaa gtagtgaatc aggttgcttt taatattatt
     5221 ggtaatgatg ttaccattac catggctgca gaggctggtc agctggaatt aaatgcgttt
     5281 gagccgatta ttttctattg catgtttcag tctatcgata ctcttggcta tgcagtccag
     5341 acattggtag ataattgtat tgtaggaatt acggcaaatg aagaaagatg ccgttatctg
     5401 gtagaaaaca gtgtaggtat tatcactgca atcagccccc atcttggata tcagaaggct
     5461 gcggatattg caaaaaaggc aattaagaca ggcgaatctg taagaagtct gattctgaaa
     5521 gaaaagctta tggacgagga tgaacttaat cgcattctgg atccgatcca tatgacggaa
     5581 cctggtattt ccggaaaaga ttatcttata aaaaaataaa gaaaaaaaca ggcgggaaaa
     5641 tcttcccgcc tgtaaaatcg tctggacaca tatcatatat aaatatgatt tttatatttt
     5701 tgaattattc gattgatttc aaccggatta gaacagacct gtgatcttac ctgtctcgtc
     5761 tacgtcgatt ctctcagcag ccggaacttt aggaagacct ggcattgtca tgatctcgcc
     5821 tgtaagagct acgatgaatc ctgcaccagc ggaaatcttc aggttacgta ctgtaacttc
     5881 gaagtcagta ggagcaccca gtttagtctg gtcatctgtt aagctgtact gtgtcttagc
     5941 tacacagatc gggcagttgc caaagccaag agcttctaac tgtttcgcct gtttctgagc
     6001 gttagctgtc agaactactt tcttaccgcc atatactttc tgaacgatct ggttcagttt
     6061 gtcttcgata gaaccttcca gttcatatgc ataggagaag tcgtttggtt cttcaacaag
     6121 acggataact tcttctgcaa gtttgattcc gccttcgccg ccttttgccc atacttcaga
     6181 aagagcaacg ttaacgccca gttctttaca tttagcttct acaaagtcaa gctctgcttt
     6241 tgtatctgta gggaatgcgt tgatagcaac aacacatgga agtttgtata cgtttttgat
     6301 gttggaaacg tgttttaaca ggttcgggat acctttttca agagcttcca ggttttcatt
     6361 gttaaggtca gctttagcaa cgccgccgtt gtatttcagg gcacgtactg tagctacgat
     6421 tacaactgcg cttggtttta aaccagccat acggcatttg atatcaagga atttctcagc
     6481 accaaggtca gcaccgaaac cagcttctgt gattgcataa tcagcaagct tcatagccat
     6541 ctttgtagct gttacagagt tacatccatg agcgatgttt gcgaatggtc cgccatgtac
     6601 gattgcagga acgtgttcca gagtctgtac aaggtttggt ttcagagcat cttttaacag
     6661 agctgtcata gcgccttctg cgtgaaggtc accggctgtt accggtttct gctcggaaac
     6721 tttaccatat gtataaccga tgatgatctt ggataatctt tctttcaggt ctttgatgtc
     6781 acttgcgagg caaagaactg ccatgatctc agatgcaact gtgatgtcgt atccgtcttc
     6841 acgaggcata ccgtttgttc ttccgccaag gccgtctact acgttacgaa gctgacggtc
     6901 gttcatatcc acacatcttc tccatgtgat cttacgtggg tcaatgttta atgcgttgcc
     6961 ctggaagata tggttatcga tcatagctgc cagtaagttg ttagctgcgc cgattgcatg
     7021 gaagtcacct gtgaagtgaa ggttgatgtc ttccatagga acaacctgtg catatccgcc
     7081 gcctgctgca ccgcctttaa caccgaatac cggtcctaag gatggctcac gaagagctac
     7141 cataacactc ttgccaagtc tctgcatacc atctgcaaga cctacagtag tagtagtttt
     7201 accttctcct gcaggagttg ggttgatagc tgtaacgagg attaattttc cgtccttctt
     7261 atcgctttct ttcagaagat tgtagtcgat ttttgctttg tattttccgt actgctccag
     7321 atatttgtcg tcaatacctg ctttttctgc aatctgagta attggaagca tctcgcattc
     7381 ctgtgcaatt tcaatgtctg atttgaatcc cataattgtt tttctccttt cgtttccgca
     7441 taacatgaaa aacttctgtt gctgttcact ccgcgatcag caacaattat taattgaaag
     7501 aagtatcggc cggtctgtct gacatttctg atttctgctc cggaaattat aaaaaaaggc
     7561 cagtatctga atacttcaaa tactgcccag acggtcggcg tccacaaacc tccgactcca
     7621 cgtggtttgc actccactct ttccgtcagt actcgaaggt tctttcaatt gatgaataca
     7681 atatatcatt ttgagaaaaa aatgtcaaga aaatttttgt tgaaacgtca aaaaatgtga
     7741 gtaaactgga taaaagttgt gcaaattgat aagagaaaag aagcgtaatc cctggtaatg
     7801 aaagaaaatg tgtttcctca aggaaatgaa ttgttaaaaa ataaacaaag tttttcctga
     7861 taaatgaaga aaatatcaaa agaaggtaaa gcctgtgcaa aatatggaaa atggaattga
     7921 caacagttaa agaggtatgt tattctcatc tttagtatga aaagacacta tcgttttcat
     7981 gcaaatattt gctcacattc agagacagtt tctgaatgtt aagccatacg gacaggcggg
     8041 gcagttgccg ggtggggaaa caccacatta ttgattgagt tagaagctca aattttataa
     8101 gttgattact ttataataat cagtgcgtaa gcacacatca tcttgtgaaa cggtcaataa
     8161 gagcatagca tatatttgcc agcgattgaa gacgacagca gtcatgaata tttcagaata
     8221 cgggaacagg cacaggatac agacggattt atacgggaaa tccggtcagt atataaagag
     8281 acagagcctg agaaattcta tagatcatga gagaagcaga tggtgaatga acttatctgc
     8341 ttcttttttt gtgcagatat agcaaatata aaggatatgg ttggagataa acgctttgcg
     8401 aggatgtgtc tcacatgcgt tcgacttgaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactggaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtatccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggttgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccattgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacaga cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctgggga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaata tcttcaggtt ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtatttt ctgacaagga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg attatcggtg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctctcaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agtagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaacagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaaa agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgcc tatgccttga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgatttccc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggatccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgttata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg attggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttccg gctttgctct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagatgtgt gtaccagagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg caatctatga
    12541 tccctgtgcg ccgggttcca ggctgggggt taccagagag aactttgacg gggaatgtct
    12601 gaaatggatc gacggactgc atttccatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcagtag aggagaagtt tggagaattt ctgtctgagg tttcctggtt
    12721 gaatatgggc ggcggacatc acattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tttggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 ctatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt aatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ctatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agctggggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggagga gactttgatg gactttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtctct ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccag gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtattacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aactttgaga gtcatgtgtt tgagggttat tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatatgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagct ggggattgtg atcccggtca gcttttatga
    14761 aaaagaggtc aataatacct ataacagcgt tgcggttctg gatgcagatg ggaagaatct
    14821 cggcgtttac cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gataccggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac ggcaagatgt atggcactgc agggagcaga
    15001 gcttctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgcg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaac ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aacggaatgc agaaatctgc
    15181 tcttaatttt tacggctctt cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccagaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 tagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaatttccgg
    15361 aatgaatttt ggctcagtta ctgagaacgg agtgaacagt aactgagttt ataagaattt
    15421 cataaaaagt ttatgattat attagttgct acctgcggta tatatggtaa aataagagta
    15481 cgaacgttac tgataacgga gcgagcagta gagttttgac atgtatttct ggcaaaatgg
    15541 agtgtagaag atgaacagaa aagaattttt ggaaatcctg agaagccagc ttgccggtca
    15601 gatgcaggag ggcaaagcag cagcacatat caggtattat gaagattata tacagtctca
    15661 ggtacgtggc ggacgttcag agcaggaagt actgcaggaa ctgggagacc cgcatctgat
    15721 agcaaaaact ctgatcgata cagatgatgg aagtacacag gaagattacg gagagtattc
    15781 ttcttatgga agcagttatg gcaatgagac agagcttcct catcagcagg agaaaagatg
    15841 gaaaaaagta atcgatcttt ctacctggca tggcagggct gttgttattg cagcggcggc
    15901 tgttataatt gttttactga tactgataat cggagttgcg attccgtttt ttattattct
    15961 tgcaattatt ctttattttc tttcatggct gaagaaaaga aatgatcaat gaaaatctgt
    16021 gcagggtttc agaaaagaaa ccctgcgcag aatcttaaaa atcttaagtg taaacgttct
    16081 tgtttcacga tattaattcc ccttgaatat ttataatcat acaatctcaa cttatttcta
    16141 ttctttaatc ctgccaggtg cagggaaaaa tcccacattc atttttatat tttttgttcg
    16201 gaaaggagac ggaaaatgaa acacaatttc aaactgaaag aacgccttgg agctttgctg
    16261 cttgcaatgc tttttattct gcaggcaatt ctggggcttg tgcctgtctg cgtaactcag
    16321 gcggcaccgt taactgtaga aacatgggac agtgacaagg tggtagagta tggttatcgc
    16381 tttaacatga agtttcagcc cggaattacc acatatgaat cttttgggtg tgataatctg
    16441 gacagggaag ctttttcaga caatggaaaa agcgaacgtg acacagagtg cgttcgtgta
    16501 ggagcggact ataaagccgg aagcgcaggg atgcgttata acaatgtagg aaaagatgga
    16561 aatggaaata ttgttgatgt cagactcatt cttgtgggag tagagaatgc agaaccccgt
    16621 tatgatctgc gcactgcaga atcgattgtt cagaataaag gcggagctac gtttgcatgg
    16681 aaagataatg aagcttatcc aatggttggc ttttccaaaa acagtatcgg tgtatttatt
    16741 tattctgtag gatacgcaaa ggttaagttt cagtttctga agcatggaac agaagaaaca
    16801 ctgccgatca gtggccatgg aaccatacgt gatattgatg cgggacaggg agtccgtatt
    16861 ccgtcagaca gcagtctgga taatgcatat gttctgaaaa acaatgatta tctgacggta
    16921 gatggaaatt ctgtaagctc accccttggt tccgttgagc cggatgatcc gagaggatgg
    16981 ctgaatcttt tttataatac agataatttt acggtagaat tctgtcatca gttcagactg
    17041 gataaatggg ataaaagtcg tgaagatgcc attgcaaaag ccggttctca ggaaagatgg
    17101 gcagagatta caagaaataa atatctggat ccatcaggca acagttattg tccgaacttt
    17161 aaaggacaga aatactgtaa agcatatgca tattttgatt ttacatccta ttgtttcggc
    17221 gatgttgaga tgaaaaaagc acctgagaaa cgtgtgggag aggcaaactg tacatgggaa
    17281 caggcagctg ctgcatcaaa agaaaaacct tttggcattc gtcagggaca ggaatttcag
    17341 tatatgatcc gggcagaggt gacacccaat agactgaaat cctttgtggt acaggatata
    17401 cttgaggatt gtcttactat agaggatgca tcaaaagtca gtattgtgaa tgatgcaggg
    17461 cagacagtga cagactggtt tgatgttgct gttgaaggac agaaagtgac ctgcagggcc
    17521 aaagcagaga gccttcagga tgaagcattt acagataatc agacttacac atttacttta
    17581 aaagtacgcc agagaccgga atcagaaatt aacatttcaa aataccttgc agaggatgga
    17641 tacagtattc ttgtaccaaa ccatgcatcc atgagttatg aacgtacaaa cggaagcgga
    17701 gatacaatgg atacggaaac agtgtgggta aagggtgtga ttccaccgga actggaagta
    17761 aagaaaaata cttctcagta tgaatggaaa acgggagata tcatagatta tgaggttctg
    17821 gtttctcaga caaaacagga tgtaaaagca gtaaatgttg ttattacaga cgagcttcca
    17881 tcatgtctgc agtttctgga agggcagtat gctgtagaga caagtcaggg aggcgagaac
    17941 tgtacgctta ccggacaggg agaaaatgga tggaaagcag agtgtccgtc cctgaagtat
    18001 ggggagacga tcacaatccg ttttaaatgt caggcatctg cggattccaa tggacaggaa
    18061 tgggaaaata ttgtgactgc aacagcggat aatctgatca atcctgagac aggagaacag
    18121 gaatccagaa aggatatggc agaagtatgg ccgaacagtc cacagcttga aattgataaa
    18181 acagcagaca aatatgaatg gcaggcagga gagcaggtag cttaccggat cgtggtgaat
    18241 aatgtaacgg caggaacaat tgcaaaagat gtaactatta ctgatattgg tctgccgcag
    18301 ggactggttc tggcaggtgg tgcacagagc atggaagtac tgggagttca gcaacaggta
    18361 aactatcccg taccggataa gaaaacagga caggcatatg aagcgagacc tgtggattct
    18421 cagttgaatg cagatgagaa cggattttcc ttttattgtt cttatgtgcc atacagtcag
    18481 cctgtaacga ttattttcca ttgtatcgca caggaagagg caaatggaca cgaaagcgta
    18541 aatgcagcaa ctgtaaaagc tgctaataca gatgagagat ctgatgatgc agaagtatat
    18601 gtaaattcag gagaattctg gattgagaaa tctgcagatc attatgaatg gcaggtcgga
    18661 gaacaggtac agtacaatgt ggtggtggag aataaaaaag caggtacagt ggcccggaac
    18721 gtaactgtct gggataccgg tatgccggca ggacttgcac tttcatcggc agaggatgta
    18781 tcggtaagcg gaatcccaca gaatattacg cagctgacag cagggaccaa agatgttttg
    18841 aaccagctca atccggaatt ttataatgag acatcagaga aaccagtgaa ttatgaattt
    18901 cttcaggagg gaagcggatg gagactgaac atttcagatc ttccggcaaa tactccggtt
    18961 atgctttctt tcctttgcac agttacggaa gcggcaaatg gaatggaaag cattaatgtt
    19021 gccaatgtgc aggcgcagaa tgcccctgtt tcacaggatg acgcagaagt gtatgtaaat
    19081 acagcagttc tttctattga gaaaagtttt cagaatccat atctggcagc cggggacgga
    19141 cgtgcggaaa atgaatttcg ggtaggagaa caggtgaatt atcaggttac ggttaataat
    19201 cttcagaagg gatctatcgc aagaaatctt gtgatcagtg atctttccct tcctgaaggg
    19261 ctggctctgg acggagctga agatgctgtt actgtaagcg gtgttccggc tgttattcag
    19321 aatccggtgg caggaactga tgatgcagga aatcagctga atccggaaaa ttataaagaa
    19381 acagtggaaa aaccggtcag ctgtcaggtt acacgtcagg gaaccggatg gatcgtgacg
    19441 atttcagatc ttccgtatca gacacctgtg actgttaatt tccgctgtac tgcgcaggaa
    19501 agcgtaaatg ggatggagat tgtaaataca gcacaggcgt atgcagataa tgcacagaaa
    19561 gtaaaggact cctcaaaaat ctgggtgaac tcacctgttc ttaaagtaga gaagacgacg
    19621 gacaaaccat tttacaaata tggtgatatt attacatacc gcattgtcct gacacaggag
    19681 cagaccggat gtgtggcgcg taatgttact ctgcaggatg tgatcgatac tcagggagta
    19741 cgtcttctga aggattcggt gattctgatg gatgagaaag gaaatgtggc agatgctgat
    19801 gtacagatca atgatgataa tactttcctg atgtcaacag gcaggacact ggtcagggac
    19861 agcagatata gtatctgcga taatgataaa ggcggtcttt ttgagcaggt aatgtataat
    19921 cctctggact gtcaggaaca gaaaagtatg atcgtggaat atcaggcagc ggtgattgat
    19981 gcagccctgg caggacagaa agtgcacaat actgcagttg cagacagcag tgaaaagata
    20041 cctgcaaccg gggaaacaga gacagaggta cacagtccga ttctggaaat tgtgaaggaa
    20101 tcagataaga aagagtatgc gtccggtgag aaaggatact ataaactgac agtaagacaa
    20161 ctgcgtgagg atgtcacaga tcagaatatt gttatcgaag ataaactgga aacccaaggg
    20221 gcttccattg taaaagacag catttttgtg aagaaaaacg gtatagaact gaaagatgcc
    20281 aaaatagagg cagatgatac aggatttgta attcagacag gagcatcgtt gtcagatatg
    20341 gataaaattg aagtctgcta tgaaatggta tttaaaacag aaagcacaga gcctgaaaaa
    20401 attgtaaaca cagcgaaagc aagaggtgat atttcaccgg aaattactgc acagcaggag
    20461 gcatatgtga aagcaaaagc agaaccgact gccacaccaa caccgtctgc aacaccgaaa
    20521 ccaacagaaa caccaaagcc gacagagaca ccaaaaccta cagaagtacc gaaaccgacg
    20581 gagcagccaa aagccacacc aacaccatct gtaccgggaa cctgcccgaa aatgactcct
    20641 gtaccgacga aagcaccgtt agcatcttac aatggtggaa ataatggagg cacgacttcc
    20701 ggaagcggag gcagcagtta cgcaaattcg ggtggatacg gaagctatca gggtggttcc
    20761 atggcaggaa gttctaaaac aggagatgtc agaccgttta aaatgatggc tgttcttggc
    20821 cttatcggaa tgggactgct gacaggaggt gtggtgatct acagaagaac tgtttccggg
    20881 aaaagaaata taaagggtat gccgcggaaa tgaaaaaact cagaacattt gcagtaagta
    20941 tgatcatagc agcaattggg cttcttatat attgtgccgg tttctatata aaaagttatg
    21001 aacagaatct tgcagcaagg caggaatatg cagagctttc ccaaatggca ggggtgaaga
    21061 acagagaagg tgccggatta ttggcagatg gcaaaaaaac tgatgaagac agcagtacaa
    21121 aaaacagtga aaaaaaacgc aggaaaaaac agagaagatc ttctgaatca aaaaacaaaa
    21181 actgtacaga tgaaatcagg gaatccttcg ggatttcctg ggaaaattta agaaagatca
    21241 actctcagac agttgcctgg attactgtcc cgggagccga tatttcttat cctgtagttc
    21301 aggcggcaga tgatgaatat tacctgaaac ataatttcag aggagaggaa gatctgtttg
    21361 gatgtatttt tctggaacat gacataaaaa agaattttac agattcccac agtattcttt
    21421 acgggcataa tatagaaggt aatatgatgt ttgcaaatct gaaccgttat gaacagcctg
    21481 aatttctgaa aaaatgtcct gaaattgaga tcacaacacc aaaaagaaag tttctgtaca
    21541 aaattttttc tgtggaacag gcatcttcca aaagcccggc atttgaatat ggatacaagt
    21601 tatccagtcc tgcatacagg agacaattat ctatattgaa aaataattcc atgtatgaca
    21661 caggagtaga gcctgatgaa agggagagaa tggtgactct gatcacctgt aattcacgtc
    21721 tggataaaga aatacgtatg gcggtacatg ggatttgcca tgaatgttat ggtatagaaa
    21781 aagctgagcc gaagtgatgt tgaaatcaat cggatattgg taattttcgt aaaggatgaa
    21841 ctgttactgt tcacacatca ctatctctcg aggtgttttg gaaaaaacta atgaaaaatc
    21901 tcccgatatt ttgtataatt tatgcataaa aaacaacttg ttcgtacgtg cgtacaagtt
    21961 gtatcctaaa tacaggaggg aagaagacat gacagataat ggaaagccga aatatttctc
    22021 actgatggaa cagctcagaa gtgatattat gtcaggagct atccgaccgg gagagaagct
    22081 tccttcagaa aacgagcttt cgcagaaata ttccctgagt agacatacag ttcgtaaagc
    22141 actgggaatc ctggagcagg acggatatgt agaggcattt cacggaagag gtacttattg
    22201 ctctgagaat atgcgccaca taaagaattc aaagaatatt gcggtagtga ccacatatat
    22261 ttctgattat atttttccga gactgataca gggaatggat aatgtccttt cagaaagcgg
    22321 ttacagtatt atcctgaaaa acacagcaaa cagcagacag aaagaggcca gatgtctgga
    22381 ggaacttctg aagaaagata ttgatggact gatcattgaa ccaagcaaaa gtgagatgat
    22441 ctgtaaacac agaaatcttt atcagaatct ggataaattt gaaattccgt atgtgtttat
    22501 tcagggaatc tattcagaaa tgagggataa acctcatatt cttatggatg atgcacaggg
    22561 aggctatctt gtaacaaaat atctgctgga actgggacat aaaaagatca agggtttctt
    22621 taaggcagac gatatgcagg gactggagcg ccacaaggga tatgtgaagg ccttacagga
    22681 gtcagggatt gcctatgatc ctgatgatgt tgtctggttt catacagagg acaggaaagt
    22741 aaaacctgca ctgatggcaa aagaaatggt acagagcgga cagcttccgg atggaatcgt
    22801 ttgttacaat gatcagattg ctgttcaggt tatggaagaa ctggagaaaa tgggagtcag
    22861 gataccggat gatatttcca ttaccggtta tgacaattca ctgtatgctc agcgaggaag
    22921 cggaatcaca acgatagctc atccgcagga aaagctggga gaaatggcag cagagcttat
    22981 acttgagaag atcaacggag ttcctgaaga agaaagtaag gttgaaagac tgatttatcc
    23041 ggaactgatc atacggggat catgcaaaaa aatattgtaa acaaatgaaa taaataaaaa
    23101 ataaatccag gaggaatttt atcatgaaaa caggaagaaa ctataagttc tggttttgta
    23161 caggttcaca ggatctttac ggagatgagt gcttaagaaa agttgctgag cattccagaa
    23221 tcattgttga ggaattaaac aagagcggt
//
