## Mon Jul  1 20:03:33 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_020687085.1/GCA_020687085.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_020687085.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_020687085.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
HGCANGJP_00001	1121115.AXVN01000048_gene1297	9.2e-242	664.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,3Y16C@572511|Blautia	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HGCANGJP_00002	1121115.AXVN01000048_gene1296	0.0	1177.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZBH@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_00003	457412.RSAG_01563	0.0	1076.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGE4@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_00004	1121115.AXVN01000048_gene1294	6.73e-103	298.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,3Y0DP@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HGCANGJP_00005	1121115.AXVN01000048_gene1293	1.65e-140	397.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3Y0XF@572511|Blautia	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
HGCANGJP_00006	457412.RSAG_01566	6.5e-124	352.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,3WIG7@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the Nudix hydrolase family	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HGCANGJP_00007	1121115.AXVN01000037_gene3239	0.0	1182.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3XYY0@572511|Blautia	186801|Clostridia	T	GTP-binding protein TypA BipA homolog	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
HGCANGJP_00008	1121115.AXVN01000037_gene3238	1.25e-148	418.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,3XZI3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
HGCANGJP_00009	457412.RSAG_02222	2.46e-108	312.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia	186801|Clostridia	H	Psort location Cytoplasmic, score	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
HGCANGJP_00010	1121115.AXVN01000125_gene3805	1.52e-207	574.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
HGCANGJP_00011	457412.RSAG_02224	1.49e-176	492.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
HGCANGJP_00012	457412.RSAG_02225	1.88e-274	754.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HGCANGJP_00013	1121115.AXVN01000104_gene847	9.54e-216	598.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
HGCANGJP_00014	1121115.AXVN01000104_gene846	0.0	1064.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,3Y116@572511|Blautia	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HGCANGJP_00015	1121115.AXVN01000104_gene845	7.3e-59	181.0	2C9HP@1|root,33Z9H@2|Bacteria,1W1CU@1239|Firmicutes,25441@186801|Clostridia,3Y0HT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00017	457412.RSAG_01508	1.76e-156	443.0	COG2755@1|root,COG2755@2|Bacteria,1VDI9@1239|Firmicutes,24MZY@186801|Clostridia	186801|Clostridia	E	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,SH3_3
HGCANGJP_00019	1121115.AXVN01000104_gene843	0.0	953.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3XYSR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
HGCANGJP_00020	457412.RSAG_01324	1.06e-118	349.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
HGCANGJP_00021	552396.HMPREF0863_00463	8.01e-290	807.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VPBW@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
HGCANGJP_00022	552396.HMPREF0863_00464	0.0	988.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,3VQ6D@526524|Erysipelotrichia	526524|Erysipelotrichia	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_00023	552396.HMPREF0863_00465	6.02e-163	457.0	COG0619@1|root,COG0619@2|Bacteria,1TTA6@1239|Firmicutes,3VQXS@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Cobalt transport protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
HGCANGJP_00024	552396.HMPREF0863_00466	8.71e-119	341.0	2BY0N@1|root,2ZBND@2|Bacteria,1TS3Y@1239|Firmicutes,3VRCG@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Hypothetical bacterial integral membrane protein (Trep_Strep)	-	-	-	-	-	-	-	-	-	-	-	-	Trep_Strep
HGCANGJP_00025	665956.HMPREF1032_02004	1.74e-225	622.0	COG2207@1|root,COG2207@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,3WH94@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
HGCANGJP_00026	1232453.BAIF02000004_gene1583	1.49e-73	225.0	2DH2E@1|root,2ZY5K@2|Bacteria,1UK9H@1239|Firmicutes,25FRH@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_00028	1121115.AXVN01000155_gene550	1.02e-182	508.0	COG1051@1|root,COG1051@2|Bacteria,1VD3G@1239|Firmicutes,25MXE@186801|Clostridia,3Y20J@572511|Blautia	186801|Clostridia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HGCANGJP_00029	471875.RUMLAC_02176	1.97e-63	193.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24PD0@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
HGCANGJP_00030	411470.RUMGNA_01472	3.71e-207	574.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,3Y2AQ@572511|Blautia	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
HGCANGJP_00031	411461.DORFOR_01985	2.34e-207	573.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ35@1239|Firmicutes,25BI3@186801|Clostridia	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_00032	411461.DORFOR_01984	1.82e-294	806.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
HGCANGJP_00033	397288.C806_00504	1.17e-58	188.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27KKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HGCANGJP_00034	1280698.AUJS01000060_gene931	5.98e-13	67.4	29VMD@1|root,30H4H@2|Bacteria,1UH45@1239|Firmicutes,250VP@186801|Clostridia,27WZ1@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00035	1280698.AUJS01000060_gene929	9.14e-13	62.4	28UT4@1|root,2ZGXB@2|Bacteria,1W41X@1239|Firmicutes,2573E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00036	457412.RSAG_01593	3.28e-17	75.1	2C9RV@1|root,32TR5@2|Bacteria,1VDVS@1239|Firmicutes,25AYH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00037	718252.FP2_17440	3.84e-37	127.0	COG1595@1|root,COG1595@2|Bacteria,1V1EX@1239|Firmicutes,24BBF@186801|Clostridia,3WJCJ@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
HGCANGJP_00038	478749.BRYFOR_06528	2.31e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00039	742765.HMPREF9457_03194	6.88e-234	645.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,27W13@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_00040	1235798.C817_01427	2.08e-12	71.2	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,27W8W@189330|Dorea	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HGCANGJP_00041	478749.BRYFOR_06534	2.86e-48	154.0	2C2RR@1|root,31NFE@2|Bacteria,1V905@1239|Firmicutes,24KRG@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00042	500632.CLONEX_00662	1.5e-151	426.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_00043	33035.JPJF01000087_gene866	0.0	1514.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3XZ9T@572511|Blautia	186801|Clostridia	MV	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HGCANGJP_00044	457412.RSAG_01517	4.22e-243	667.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
HGCANGJP_00045	457412.RSAG_01516	1.73e-183	512.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,3WIAX@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate ABC transporter, permease protein CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
HGCANGJP_00046	457412.RSAG_01515	6.02e-182	508.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,3WHKV@541000|Ruminococcaceae	186801|Clostridia	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
HGCANGJP_00047	457412.RSAG_01514	3.1e-246	677.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WSP6@541000|Ruminococcaceae	186801|Clostridia	E	ATPases associated with a variety of cellular activities	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
HGCANGJP_00048	1121115.AXVN01000104_gene849	0.0	1100.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HGCANGJP_00049	1121115.AXVN01000104_gene848	4.22e-74	221.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,3Y1XY@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
HGCANGJP_00050	411471.SUBVAR_04358	1.27e-73	221.0	COG1476@1|root,COG1476@2|Bacteria,1V4DH@1239|Firmicutes,24HSN@186801|Clostridia,3WPA3@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_00051	1121115.AXVN01000040_gene3780	5.06e-35	119.0	COG2909@1|root,COG2909@2|Bacteria,1VMYN@1239|Firmicutes	1239|Firmicutes	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00052	411467.BACCAP_03380	1.37e-150	424.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,268QZ@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00053	411467.BACCAP_03381	5.77e-228	635.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,268Q4@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_00054	411467.BACCAP_03382	3.32e-142	403.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,267ZI@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_00055	1226325.HMPREF1548_01839	0.0	1063.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,36DMM@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HGCANGJP_00056	457412.RSAG_02032	2.17e-39	130.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3WM0N@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HGCANGJP_00057	1121115.AXVN01000152_gene3982	4.48e-161	451.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,3XZF5@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00058	457412.RSAG_02030	1.14e-233	644.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,3WJ5X@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_00059	457412.RSAG_02029	1.67e-151	427.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WH0X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_00060	1235800.C819_00258	0.0	900.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,27I9M@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HGCANGJP_00061	1121115.AXVN01000148_gene3604	3.08e-43	141.0	2E98V@1|root,333H5@2|Bacteria,1VI8K@1239|Firmicutes,24RMD@186801|Clostridia	186801|Clostridia	S	BhlA holin family	-	-	-	-	-	-	-	-	-	-	-	-	Holin_BhlA
HGCANGJP_00062	1121115.AXVN01000148_gene3603	1.7e-118	339.0	2EGBC@1|root,33A36@2|Bacteria,1UKIB@1239|Firmicutes,24VNX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00063	1121115.AXVN01000148_gene3602	0.0	1791.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,3XZVN@572511|Blautia	186801|Clostridia	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
HGCANGJP_00065	1121115.AXVN01000148_gene3601	2.09e-81	254.0	COG3290@1|root,COG3290@2|Bacteria,1UFBB@1239|Firmicutes,24RSK@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_00066	891391.LAC30SC_01360	2.41e-49	179.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	int7	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HGCANGJP_00072	411459.RUMOBE_01397	4.89e-70	211.0	2DWWM@1|root,34290@2|Bacteria,1VWVN@1239|Firmicutes,251UC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00073	397290.C810_01426	1.56e-39	148.0	COG1674@1|root,COG1787@1|root,COG1674@2|Bacteria,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,27MRP@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
HGCANGJP_00074	411459.RUMOBE_01396	6.65e-23	89.0	2ESED@1|root,30GTB@2|Bacteria,1UGKB@1239|Firmicutes,25P2V@186801|Clostridia,3Y23S@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00075	411459.RUMOBE_01395	4.32e-32	112.0	29UVC@1|root,30G7T@2|Bacteria,1UFE0@1239|Firmicutes,25PDS@186801|Clostridia,3Y25R@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00076	411902.CLOBOL_02557	3.06e-16	84.0	2C3RZ@1|root,33PBS@2|Bacteria,1VSX3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00077	411470.RUMGNA_03232	4.25e-61	198.0	COG3646@1|root,COG3646@2|Bacteria,1VFZC@1239|Firmicutes,24AEZ@186801|Clostridia,3Y0MR@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	rha	-	-	-	-	-	-	-	-	-	-	-	ANT,ORF6C,Phage_pRha
HGCANGJP_00079	411459.RUMOBE_01384	0.0	986.0	COG5412@1|root,COG5412@2|Bacteria,1TRXJ@1239|Firmicutes,25MTF@186801|Clostridia,3Y04H@572511|Blautia	186801|Clostridia	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00080	411459.RUMOBE_01382	1.4e-62	195.0	2BXDI@1|root,2ZGQ2@2|Bacteria,1UGM8@1239|Firmicutes,25A8V@186801|Clostridia,3Y0U8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00083	411459.RUMOBE_01390	6.4e-51	162.0	2FKR9@1|root,2ZUC3@2|Bacteria,1W69M@1239|Firmicutes,255P4@186801|Clostridia,3Y25W@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00088	411459.RUMOBE_01378	4.04e-254	717.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia,3Y0S5@572511|Blautia	186801|Clostridia	S	D5 N terminal like	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
HGCANGJP_00092	1121115.AXVN01000001_gene1092	1.21e-75	226.0	COG1669@1|root,COG1669@2|Bacteria,1VFCZ@1239|Firmicutes,24N6Y@186801|Clostridia,3Y07H@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
HGCANGJP_00093	1121115.AXVN01000001_gene1093	1.99e-285	780.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3XYJM@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
HGCANGJP_00094	1121115.AXVN01000001_gene1094	5.95e-215	595.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
HGCANGJP_00095	1121115.AXVN01000001_gene1095	0.0	1937.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3XYK7@572511|Blautia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
HGCANGJP_00096	1121115.AXVN01000001_gene1096	8.03e-159	445.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3XZ9W@572511|Blautia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
HGCANGJP_00097	1121115.AXVN01000001_gene1097	6.78e-42	137.0	COG0236@1|root,COG0236@2|Bacteria,1UGNP@1239|Firmicutes,25P5Y@186801|Clostridia,3Y0KT@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HGCANGJP_00098	1121115.AXVN01000001_gene1098	2.93e-236	651.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3XYGR@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
HGCANGJP_00099	457412.RSAG_01204	0.0	1156.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,3WGT9@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HGCANGJP_00100	457412.RSAG_01205	4.74e-177	495.0	2ESCZ@1|root,33JXR@2|Bacteria,1VRFX@1239|Firmicutes,24YXB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00101	457412.RSAG_01206	3.82e-168	470.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,3WRJJ@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_00102	1121115.AXVN01000001_gene1102	0.0	1232.0	COG3290@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5002@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3Y0QU@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_00103	1121115.AXVN01000001_gene1103	0.0	1370.0	2E7W1@1|root,332AT@2|Bacteria,1UYG9@1239|Firmicutes,24B0R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00104	1121115.AXVN01000001_gene1104	1e-309	846.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYPG@572511|Blautia	186801|Clostridia	V	COG COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00105	1121115.AXVN01000001_gene1105	3.15e-38	127.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3Y0IR@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
HGCANGJP_00106	457412.RSAG_01211	2.07e-124	354.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHK@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
HGCANGJP_00107	457412.RSAG_01212	1.21e-305	833.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
HGCANGJP_00108	457412.RSAG_01213	1.34e-232	641.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
HGCANGJP_00109	457412.RSAG_04661	1.29e-313	856.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
HGCANGJP_00110	1121115.AXVN01000001_gene1110	4.43e-178	497.0	COG2865@1|root,COG2865@2|Bacteria,1TQXE@1239|Firmicutes,249ND@186801|Clostridia,3XZUK@572511|Blautia	186801|Clostridia	K	COG NOG11764 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00111	1121115.AXVN01000001_gene1111	8.76e-85	251.0	COG1340@1|root,COG1340@2|Bacteria,1V7S0@1239|Firmicutes,24KZW@186801|Clostridia	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
HGCANGJP_00112	457412.RSAG_01218	4.68e-98	287.0	2CJ2H@1|root,33QUA@2|Bacteria,1VSMM@1239|Firmicutes,24Z9D@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
HGCANGJP_00113	457412.RSAG_01219	1.91e-297	812.0	COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,24921@186801|Clostridia	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
HGCANGJP_00114	1121115.AXVN01000001_gene1114	9.05e-188	521.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3Y16A@572511|Blautia	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HGCANGJP_00115	457412.RSAG_01221	2.57e-200	557.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
HGCANGJP_00116	1121115.AXVN01000001_gene1116	3.29e-235	648.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
HGCANGJP_00117	457412.RSAG_01223	1.52e-263	721.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HGCANGJP_00118	457412.RSAG_01224	0.0	870.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
HGCANGJP_00119	1121115.AXVN01000001_gene1119	3.78e-57	177.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3Y0FS@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
HGCANGJP_00120	1121115.AXVN01000001_gene1120	3.06e-195	540.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3XYGN@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
HGCANGJP_00121	1121115.AXVN01000001_gene1121	2.34e-140	396.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3Y05Z@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
HGCANGJP_00122	457412.RSAG_01228	0.0	1789.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
HGCANGJP_00123	1121115.AXVN01000001_gene1123	1.61e-73	221.0	2ETPV@1|root,33M7I@2|Bacteria,1VNHF@1239|Firmicutes,25A5M@186801|Clostridia,3Y0Q4@572511|Blautia	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
HGCANGJP_00124	1121115.AXVN01000001_gene1124	0.0	1222.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XZ55@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HGCANGJP_00126	457412.RSAG_01231	1.43e-197	554.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	FMN_bind,Flg_new,LRR_5
HGCANGJP_00127	457412.RSAG_01232	0.0	916.0	COG0584@1|root,COG0584@2|Bacteria,1VB6Y@1239|Firmicutes,24KSW@186801|Clostridia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,GDPD
HGCANGJP_00128	1121115.AXVN01000001_gene1127	1.23e-51	162.0	2FADH@1|root,342MV@2|Bacteria,1VXR1@1239|Firmicutes,252AC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00129	1121115.AXVN01000001_gene1128	0.0	882.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3XZ9R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HGCANGJP_00130	1121115.AXVN01000001_gene1129	2.17e-209	578.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3XYV8@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
HGCANGJP_00131	457412.RSAG_04660	1.45e-181	510.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,3WGVT@541000|Ruminococcaceae	186801|Clostridia	P	Mg2 transporter protein CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
HGCANGJP_00132	457412.RSAG_01238	9.11e-261	714.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
HGCANGJP_00133	1121115.AXVN01000001_gene1132	2.96e-266	728.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia,3XZ28@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
HGCANGJP_00134	1121115.AXVN01000001_gene1133	3.95e-311	847.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HGCANGJP_00135	457412.RSAG_01241	1.03e-236	650.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WGUW@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
HGCANGJP_00136	1121115.AXVN01000001_gene1135	0.0	978.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3XZE7@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
HGCANGJP_00137	1121115.AXVN01000001_gene1136	9.93e-213	588.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3XYIS@572511|Blautia	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
HGCANGJP_00138	1121115.AXVN01000001_gene1137	6.25e-112	322.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,3Y08Y@572511|Blautia	186801|Clostridia	H	precorrin-2 oxidase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
HGCANGJP_00139	1121115.AXVN01000001_gene1138	3.92e-294	803.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3XZQJ@572511|Blautia	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,NAD_binding_7,Shikimate_DH
HGCANGJP_00140	1121115.AXVN01000001_gene1139	0.0	1139.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_00141	1121115.AXVN01000001_gene1140	3.66e-186	518.0	2DEAV@1|root,2ZM6Y@2|Bacteria,1V2HI@1239|Firmicutes,24GNN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00142	1121115.AXVN01000001_gene1141	6.61e-166	464.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,3XYRX@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00143	457412.RSAG_01250	0.0	979.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,3WG8P@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
HGCANGJP_00144	1121115.AXVN01000001_gene1143	2.75e-153	431.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3XZJS@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HGCANGJP_00145	1121115.AXVN01000001_gene1144	8.23e-305	833.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3XZ2Q@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HGCANGJP_00146	1121115.AXVN01000001_gene1145	5.32e-242	665.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,3Y01C@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
HGCANGJP_00147	457412.RSAG_02566	6.85e-132	374.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,3WKCT@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
HGCANGJP_00148	457412.RSAG_02565	1.57e-300	818.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HGCANGJP_00149	1121115.AXVN01000008_gene2686	3.86e-142	401.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_00150	457412.RSAG_02563	0.0	975.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,3WHIY@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
HGCANGJP_00151	457412.RSAG_02135	5.63e-198	550.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
HGCANGJP_00152	1121115.AXVN01000022_gene1735	1.78e-301	824.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,24IXJ@186801|Clostridia,3Y2B7@572511|Blautia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
HGCANGJP_00153	457412.RSAG_02133	3.05e-57	177.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,3WM6W@541000|Ruminococcaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HGCANGJP_00154	457412.RSAG_02132	0.0	1632.0	COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1V0DN@1239|Firmicutes,24BCJ@186801|Clostridia,3WGYS@541000|Ruminococcaceae	186801|Clostridia	D	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,YkuD
HGCANGJP_00155	1121115.AXVN01000153_gene3989	3.52e-297	809.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,3Y0YH@572511|Blautia	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HGCANGJP_00156	1121115.AXVN01000153_gene3988	1.14e-165	463.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,3Y0X3@572511|Blautia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
HGCANGJP_00157	457412.RSAG_03445	5.98e-242	664.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3WGM8@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
HGCANGJP_00158	457412.RSAG_03446	4.53e-132	375.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,3WK6N@541000|Ruminococcaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HGCANGJP_00159	1121115.AXVN01000153_gene3985	1.66e-101	294.0	COG3610@1|root,COG3610@2|Bacteria,1UVFM@1239|Firmicutes,257UX@186801|Clostridia,3Y1J9@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
HGCANGJP_00160	1121115.AXVN01000153_gene3984	3.4e-178	496.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,3Y0H6@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HGCANGJP_00161	411483.FAEPRAA2165_00895	1.98e-33	115.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3WM0N@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HGCANGJP_00162	33035.JPJF01000087_gene870	1.34e-153	432.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,3Y06R@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00163	500632.CLONEX_00652	1.19e-231	639.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
HGCANGJP_00164	33035.JPJF01000087_gene868	5.21e-178	496.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3XYJP@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_00165	411483.FAEPRAA2165_00899	0.0	1401.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3WGQ2@541000|Ruminococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HGCANGJP_00166	457412.RSAG_01692	1.29e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,3WH9J@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00167	457412.RSAG_01693	4.04e-264	725.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,3WSRQ@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_00168	457412.RSAG_01694	1.14e-252	693.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3WH25@541000|Ruminococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
HGCANGJP_00169	457412.RSAG_01696	6.48e-99	286.0	COG3543@1|root,COG3543@2|Bacteria,1VAZC@1239|Firmicutes,25DS7@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
HGCANGJP_00170	1121115.AXVN01000107_gene614	6.45e-203	563.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,3XYIR@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HGCANGJP_00171	1121115.AXVN01000098_gene2878	1.5e-299	816.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,3XZP1@572511|Blautia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
HGCANGJP_00172	457412.RSAG_01933	4.2e-222	615.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,24AF9@186801|Clostridia,3WNDD@541000|Ruminococcaceae	186801|Clostridia	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
HGCANGJP_00173	1121115.AXVN01000098_gene2880	1.27e-190	531.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
HGCANGJP_00174	1121115.AXVN01000098_gene2881	1.24e-79	236.0	2DYSA@1|root,34AWR@2|Bacteria,1VZ6D@1239|Firmicutes,250AC@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
HGCANGJP_00175	457412.RSAG_01930	2.27e-88	260.0	2CV0R@1|root,32SWK@2|Bacteria,1VDAN@1239|Firmicutes,24K0G@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
HGCANGJP_00176	1121115.AXVN01000107_gene613	1.3e-130	371.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3Y0SC@572511|Blautia	186801|Clostridia	S	Thiamine-precursor transporter protein (ThiW)	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
HGCANGJP_00177	1121115.AXVN01000107_gene612	1.92e-145	412.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3XZZP@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
HGCANGJP_00178	1121115.AXVN01000107_gene611	0.0	868.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XZ7Z@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00179	585394.RHOM_06060	1.17e-07	54.3	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,247QK@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
HGCANGJP_00180	1121115.AXVN01000107_gene610	2.81e-316	862.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3Y07Q@572511|Blautia	186801|Clostridia	P	Voltage gated chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
HGCANGJP_00181	1121115.AXVN01000167_gene720	0.0	2276.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Germane,Gmad1
HGCANGJP_00182	411469.EUBHAL_01615	4.67e-164	466.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HGCANGJP_00183	537007.BLAHAN_04059	2.16e-05	45.4	2EHNJ@1|root,33BEC@2|Bacteria,1VQF0@1239|Firmicutes,24V53@186801|Clostridia,3Y1V8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00184	500632.CLONEX_03998	2.91e-239	660.0	COG3843@1|root,COG3843@2|Bacteria,1UZXP@1239|Firmicutes	1239|Firmicutes	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HGCANGJP_00185	500632.CLONEX_03997	1.67e-67	205.0	2DJY1@1|root,307TR@2|Bacteria,1V50J@1239|Firmicutes,24I18@186801|Clostridia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HGCANGJP_00186	1226325.HMPREF1548_01583	2e-29	104.0	2E3DV@1|root,32YCY@2|Bacteria,1VH0W@1239|Firmicutes,24TDH@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00187	658655.HMPREF0988_03170	0.0	899.0	2CET6@1|root,2Z92J@2|Bacteria,1TQGV@1239|Firmicutes,24ARS@186801|Clostridia,27RTG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00188	457412.RSAG_03155	0.0	2471.0	COG2340@1|root,COG2340@2|Bacteria,1VQX9@1239|Firmicutes,24ZHD@186801|Clostridia	186801|Clostridia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00189	457412.RSAG_02194	2.42e-79	236.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WKJ7@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
HGCANGJP_00190	1121115.AXVN01000146_gene775	7.72e-165	461.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3Y00D@572511|Blautia	186801|Clostridia	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HGCANGJP_00191	1121115.AXVN01000146_gene774	1.2e-162	457.0	COG0568@1|root,COG0568@2|Bacteria,1VJ02@1239|Firmicutes,24RNB@186801|Clostridia,3Y0EP@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
HGCANGJP_00199	1121115.AXVN01000146_gene773	7.13e-115	328.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3Y05G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HGCANGJP_00200	457412.RSAG_02198	2.26e-135	383.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
HGCANGJP_00201	1121115.AXVN01000146_gene771	3.17e-282	770.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3XYQ3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
HGCANGJP_00202	1121115.AXVN01000146_gene770	7.16e-132	373.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3XZ4B@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HGCANGJP_00203	1121115.AXVN01000198_gene2447	4.26e-69	208.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,3Y0GN@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HGCANGJP_00204	1121115.AXVN01000198_gene2446	1.69e-33	115.0	2FGU2@1|root,348PD@2|Bacteria,1VZBU@1239|Firmicutes,252UE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00205	1121115.AXVN01000106_gene672	0.0	1075.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3XYGM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
HGCANGJP_00206	1121115.AXVN01000106_gene671	0.0	1024.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia,3XYUS@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
HGCANGJP_00207	1121115.AXVN01000106_gene670	9.56e-267	729.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia,3Y051@572511|Blautia	186801|Clostridia	K	Periplasmic binding protein-like domain	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
HGCANGJP_00208	457412.RSAG_03399	4.47e-199	553.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3WK8B@541000|Ruminococcaceae	186801|Clostridia	S	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
HGCANGJP_00209	1121115.AXVN01000106_gene668	0.0	2967.0	COG3468@1|root,COG4932@1|root,COG3468@2|Bacteria,COG4932@2|Bacteria,1UVFP@1239|Firmicutes,25MSF@186801|Clostridia,3Y1Y1@572511|Blautia	186801|Clostridia	M	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00210	457412.RSAG_03397	1.38e-91	269.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia,3WMFG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HGCANGJP_00211	1121115.AXVN01000128_gene272	1.45e-215	595.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
HGCANGJP_00212	1121115.AXVN01000128_gene273	1.1e-283	773.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia	186801|Clostridia	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
HGCANGJP_00213	1121115.AXVN01000128_gene274	6.88e-281	766.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3XYIP@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
HGCANGJP_00214	1121115.AXVN01000128_gene275	8.26e-309	841.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3XYN8@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
HGCANGJP_00215	1121115.AXVN01000128_gene276	9.27e-217	597.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3XZ5Q@572511|Blautia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
HGCANGJP_00216	1121115.AXVN01000128_gene277	0.0	947.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XZBZ@572511|Blautia	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain protein	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HGCANGJP_00217	457412.RSAG_03390	0.0	1102.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
HGCANGJP_00218	1121115.AXVN01000030_gene3606	0.0	930.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,3Y0Z4@572511|Blautia	186801|Clostridia	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
HGCANGJP_00219	1121115.AXVN01000030_gene3607	2.29e-225	620.0	COG0583@1|root,COG0583@2|Bacteria,1UYAI@1239|Firmicutes,24BA8@186801|Clostridia,3XZQR@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_00220	457412.RSAG_03387	0.0	975.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3WGAY@541000|Ruminococcaceae	186801|Clostridia	G	Sugar (pentulose and hexulose) kinases	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
HGCANGJP_00221	457412.RSAG_03386	0.0	1013.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
HGCANGJP_00222	457412.RSAG_03385	1.65e-147	415.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,3WIDK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
HGCANGJP_00223	1121115.AXVN01000030_gene3611	5.09e-203	561.0	COG2207@1|root,COG2207@2|Bacteria,1V48H@1239|Firmicutes,248BW@186801|Clostridia,3XZC4@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_00224	457412.RSAG_03383	7.32e-90	264.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,3WK1B@541000|Ruminococcaceae	186801|Clostridia	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
HGCANGJP_00225	1121115.AXVN01000030_gene3613	0.0	1002.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3XZAA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
HGCANGJP_00226	457412.RSAG_03365	0.0	913.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3WH2V@541000|Ruminococcaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
HGCANGJP_00227	1121115.AXVN01000030_gene3615	2.71e-240	662.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HGCANGJP_00228	457412.RSAG_03363	2.72e-173	482.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
HGCANGJP_00229	457412.RSAG_03362	5.71e-116	332.0	COG0454@1|root,COG0454@2|Bacteria,1V9X4@1239|Firmicutes,24G56@186801|Clostridia,3WSS2@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_00230	1121115.AXVN01000030_gene3618	2.31e-35	120.0	2DDM6@1|root,32U1S@2|Bacteria,1URV4@1239|Firmicutes,259SN@186801|Clostridia,3Y1XH@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00231	457412.RSAG_03360	1.37e-249	684.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3WG84@541000|Ruminococcaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
HGCANGJP_00232	457412.RSAG_03358	1.15e-278	763.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3WS0T@541000|Ruminococcaceae	186801|Clostridia	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2,LuxC
HGCANGJP_00233	457412.RSAG_03357	0.0	900.0	COG1964@1|root,COG1964@2|Bacteria,1TVES@1239|Firmicutes,248NC@186801|Clostridia,3WJ5T@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
HGCANGJP_00234	1121115.AXVN01000030_gene3623	5.63e-102	295.0	2E4P6@1|root,32ZHX@2|Bacteria,1VCAE@1239|Firmicutes,24PE5@186801|Clostridia,3Y172@572511|Blautia	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
HGCANGJP_00235	1121115.AXVN01000030_gene3624	3.99e-123	351.0	COG0500@1|root,COG2226@2|Bacteria,1UDBU@1239|Firmicutes,25I0S@186801|Clostridia,3Y12S@572511|Blautia	186801|Clostridia	H	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HGCANGJP_00236	1121115.AXVN01000030_gene3625	1.13e-48	154.0	2EGAW@1|root,33A2R@2|Bacteria,1VMAM@1239|Firmicutes,24WIE@186801|Clostridia,3Y1R7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00237	457412.RSAG_03353	0.0	1499.0	COG0247@1|root,COG0493@1|root,COG0247@2|Bacteria,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WNTW@541000|Ruminococcaceae	186801|Clostridia	CE	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_20,Pyr_redox_2
HGCANGJP_00238	1121115.AXVN01000030_gene3627	0.0	1855.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3Y192@572511|Blautia	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	mop	-	1.2.99.7	ko:K07469	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
HGCANGJP_00239	1121115.AXVN01000030_gene3628	5.52e-55	171.0	2E80U@1|root,3094H@2|Bacteria,1U4EU@1239|Firmicutes,2520R@186801|Clostridia,3Y1V4@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00240	1121115.AXVN01000030_gene3629	1.33e-223	616.0	COG2005@1|root,COG2068@1|root,COG2005@2|Bacteria,COG2068@2|Bacteria,1V2BH@1239|Firmicutes,25CV9@186801|Clostridia	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,NTP_transf_3
HGCANGJP_00241	1121115.AXVN01000030_gene3630	4.45e-253	694.0	COG0406@1|root,COG1418@1|root,COG0406@2|Bacteria,COG1418@2|Bacteria,1TTYI@1239|Firmicutes,25KH7@186801|Clostridia,3Y1F0@572511|Blautia	186801|Clostridia	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HGCANGJP_00242	1121115.AXVN01000030_gene3631	3.32e-240	660.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,3Y1BH@572511|Blautia	186801|Clostridia	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HGCANGJP_00243	411459.RUMOBE_01444	5.54e-209	577.0	COG4122@1|root,COG4122@2|Bacteria,1VKRG@1239|Firmicutes,24HG7@186801|Clostridia,3Y11Q@572511|Blautia	186801|Clostridia	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
HGCANGJP_00244	411459.RUMOBE_01442	2.79e-260	714.0	COG0614@1|root,COG0614@2|Bacteria,1TQ11@1239|Firmicutes,2482R@186801|Clostridia,3XZZ5@572511|Blautia	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HGCANGJP_00245	1121115.AXVN01000030_gene3634	5e-218	605.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3XZEF@572511|Blautia	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HGCANGJP_00246	1121115.AXVN01000030_gene3635	6.65e-192	532.0	COG1120@1|root,COG1120@2|Bacteria,1UYT8@1239|Firmicutes,24CJY@186801|Clostridia,3Y057@572511|Blautia	186801|Clostridia	HP	Psort location CytoplasmicMembrane, score	-	-	3.6.3.34	ko:K02013,ko:K09820	ko02010,map02010	M00240,M00243	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.15	-	-	ABC_tran
HGCANGJP_00247	411459.RUMOBE_01438	1.17e-114	329.0	COG1618@1|root,COG1618@2|Bacteria,1VGU5@1239|Firmicutes,24QRA@186801|Clostridia,3Y0TU@572511|Blautia	186801|Clostridia	F	NTPase	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
HGCANGJP_00249	1121115.AXVN01000030_gene3637	1.86e-270	743.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ8E@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HGCANGJP_00250	457412.RSAG_03345	5.43e-289	806.0	COG0845@1|root,COG0845@2|Bacteria,1UZA4@1239|Firmicutes,24BV0@186801|Clostridia,3WJXH@541000|Ruminococcaceae	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HGCANGJP_00251	1121115.AXVN01000030_gene3639	4.29e-171	478.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3XYST@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_00252	1121115.AXVN01000030_gene3640	0.0	895.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3XZF0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
HGCANGJP_00253	457412.RSAG_03342	0.0	1131.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,3WHYM@541000|Ruminococcaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
HGCANGJP_00254	1121115.AXVN01000030_gene3642	4.61e-167	468.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,3XZX5@572511|Blautia	186801|Clostridia	K	FCD domain	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
HGCANGJP_00255	1121115.AXVN01000030_gene3643	2.2e-61	188.0	2CA4P@1|root,33W70@2|Bacteria,1VVK6@1239|Firmicutes,251F5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00256	1121115.AXVN01000205_gene3700	1.45e-38	128.0	2EMF6@1|root,33F40@2|Bacteria,1VPJF@1239|Firmicutes,24VFH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00257	1121115.AXVN01000205_gene3699	2.02e-43	141.0	2CCVX@1|root,33G73@2|Bacteria,1VN7A@1239|Firmicutes,24W0K@186801|Clostridia,3Y25Z@572511|Blautia	186801|Clostridia	S	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
HGCANGJP_00258	1121115.AXVN01000117_gene3359	4.17e-88	259.0	COG1848@1|root,COG1848@2|Bacteria,1VFQN@1239|Firmicutes,24NXI@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
HGCANGJP_00260	1121115.AXVN01000117_gene3357	3.43e-96	280.0	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00262	1121115.AXVN01000117_gene3355	5.28e-127	360.0	2EWQA@1|root,33Q24@2|Bacteria,1VRMX@1239|Firmicutes,24NS4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00263	1121115.AXVN01000117_gene3354	2.05e-257	707.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3Y1W9@572511|Blautia	186801|Clostridia	M	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HGCANGJP_00265	1121115.AXVN01000117_gene3352	2.94e-172	479.0	29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes,24IF4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00266	319236.JCM19294_2253	3.95e-06	51.2	COG3682@1|root,COG3682@2|Bacteria,4NP4S@976|Bacteroidetes,1I229@117743|Flavobacteriia,3HKCN@363408|Nonlabens	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HGCANGJP_00267	273068.TTE1079	4.62e-12	77.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,42IB4@68295|Thermoanaerobacterales	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56
HGCANGJP_00268	1536770.R50345_25050	2.69e-39	139.0	COG1595@1|root,COG1595@2|Bacteria,1V9GU@1239|Firmicutes,4IPSQ@91061|Bacilli,26V2S@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HGCANGJP_00269	1121115.AXVN01000117_gene3349	7.29e-149	421.0	2EBGZ@1|root,335HI@2|Bacteria,1VI7Q@1239|Firmicutes,24RN0@186801|Clostridia,3Y218@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00277	457412.RSAG_03441	1.32e-171	480.0	COG2207@1|root,COG2207@2|Bacteria,1U23Q@1239|Firmicutes,25BMJ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HGCANGJP_00278	1121115.AXVN01000161_gene1326	2.85e-153	429.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3Y0I8@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HGCANGJP_00279	1121115.AXVN01000161_gene1325	3.25e-145	410.0	COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,249IY@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HGCANGJP_00280	1121115.AXVN01000161_gene1324	1.49e-153	432.0	COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,24823@186801|Clostridia	186801|Clostridia	P	acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HGCANGJP_00281	1121115.AXVN01000161_gene1323	1.95e-171	479.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HGCANGJP_00282	1235792.C808_03115	1.36e-57	183.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,24G35@186801|Clostridia,27MA3@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF2992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2992
HGCANGJP_00283	742738.HMPREF9460_02035	3.8e-106	308.0	COG1695@1|root,COG1695@2|Bacteria,1V1R5@1239|Firmicutes,24FU3@186801|Clostridia,26BM0@186813|unclassified Clostridiales	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
HGCANGJP_00284	445972.ANACOL_00956	8.99e-283	778.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WHPE@541000|Ruminococcaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00285	718252.FP2_17280	1.97e-108	313.0	COG1695@1|root,COG1695@2|Bacteria,1V1R5@1239|Firmicutes,24FU3@186801|Clostridia,3WIJF@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34,PadR,Vir_act_alpha_C
HGCANGJP_00286	457412.RSAG_01796	8.48e-145	408.0	COG1247@1|root,COG1247@2|Bacteria,1UKI4@1239|Firmicutes,25FXM@186801|Clostridia	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_00287	1121115.AXVN01000119_gene3268	0.0	949.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,3XZRQ@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
HGCANGJP_00288	1121115.AXVN01000119_gene3269	2.28e-121	347.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3Y01B@572511|Blautia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
HGCANGJP_00289	1232452.BAIB02000008_gene1831	3.65e-74	223.0	COG1476@1|root,COG1476@2|Bacteria,1V353@1239|Firmicutes,25KI0@186801|Clostridia,26BKJ@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00290	1121115.AXVN01000110_gene2332	0.0	993.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3Y14D@572511|Blautia	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HGCANGJP_00291	1121115.AXVN01000119_gene3271	0.0	896.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
HGCANGJP_00292	1121115.AXVN01000119_gene3270	0.0	1097.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,3Y0D1@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00293	411470.RUMGNA_00730	0.0	898.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3XZ6Y@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HGCANGJP_00294	742765.HMPREF9457_03295	1.97e-92	270.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,27VXG@189330|Dorea	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
HGCANGJP_00295	411459.RUMOBE_01930	7.03e-156	436.0	COG3506@1|root,COG3506@2|Bacteria,1TSXY@1239|Firmicutes,2484H@186801|Clostridia	186801|Clostridia	F	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
HGCANGJP_00296	658088.HMPREF0987_00288	2.28e-26	103.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia,27NHN@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HGCANGJP_00297	657322.FPR_07260	3.26e-108	317.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia,3WKUN@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HGCANGJP_00300	457412.RSAG_00904	0.0	891.0	COG5279@1|root,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HGCANGJP_00301	1121115.AXVN01000107_gene609	0.0	1423.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
HGCANGJP_00302	518637.EUBIFOR_00452	1.44e-220	614.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,3VQ1Q@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14
HGCANGJP_00303	411461.DORFOR_02070	8.44e-72	217.0	2DMY9@1|root,32UCT@2|Bacteria,1VAN7@1239|Firmicutes,24PHY@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_00304	742765.HMPREF9457_03057	2.25e-80	246.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia,27WDZ@189330|Dorea	186801|Clostridia	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
HGCANGJP_00305	1121115.AXVN01000131_gene739	0.000654	42.4	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_00306	457412.RSAG_02293	2.28e-113	325.0	COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia,3WJJI@541000|Ruminococcaceae	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_00307	1121115.AXVN01000038_gene3346	5.82e-105	302.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3Y0WP@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
HGCANGJP_00308	1121115.AXVN01000038_gene3338	2.74e-88	258.0	2E2GC@1|root,32XKF@2|Bacteria,1VCKF@1239|Firmicutes,24QFN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00309	515620.EUBELI_20270	1.34e-86	257.0	COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,24HH2@186801|Clostridia,25W9B@186806|Eubacteriaceae	186801|Clostridia	S	Aminoacyl-tRNA editing domain	EbsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
HGCANGJP_00310	1121115.AXVN01000038_gene3326	6.34e-190	528.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3XYTE@572511|Blautia	186801|Clostridia	H	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
HGCANGJP_00311	1121115.AXVN01000038_gene3325	3.15e-295	807.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3XZ6H@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00312	457412.RSAG_02286	0.0	903.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3WHVA@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	gph	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
HGCANGJP_00313	457412.RSAG_02285	2.29e-252	691.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3WI2M@541000|Ruminococcaceae	186801|Clostridia	C	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
HGCANGJP_00314	457412.RSAG_02284	9.16e-264	723.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WH5F@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
HGCANGJP_00315	1121115.AXVN01000038_gene3321	4.41e-305	833.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,2481G@186801|Clostridia,3XYVW@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00316	1235792.C808_03815	1.32e-193	551.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,27I7H@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00317	457412.RSAG_02280	0.0	1604.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_00318	457412.RSAG_02279	1.41e-143	405.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,3WRQY@541000|Ruminococcaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
HGCANGJP_00319	1121115.AXVN01000038_gene3316	2.69e-91	266.0	COG1669@1|root,COG1669@2|Bacteria,1U3WZ@1239|Firmicutes,25933@186801|Clostridia,3Y22N@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
HGCANGJP_00320	1121115.AXVN01000038_gene3315	1.94e-60	186.0	COG1669@1|root,COG1669@2|Bacteria,1VEWI@1239|Firmicutes,25DNH@186801|Clostridia,3Y1WZ@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
HGCANGJP_00321	1121115.AXVN01000038_gene3314	1.9e-140	397.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3XZK2@572511|Blautia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
HGCANGJP_00324	1121115.AXVN01000175_gene3962	3.2e-95	278.0	2DNMV@1|root,32Y6A@2|Bacteria,1VFC4@1239|Firmicutes,24QMI@186801|Clostridia,3Y0RH@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00325	1121115.AXVN01000175_gene3963	2.79e-224	617.0	COG3103@1|root,COG3103@2|Bacteria,1VAHD@1239|Firmicutes,24NRJ@186801|Clostridia,3Y237@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
HGCANGJP_00326	1280664.AUIX01000072_gene1576	1.95e-124	369.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,4BYWZ@830|Butyrivibrio	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_00327	457412.RSAG_02270	6.6e-102	302.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,3WIMK@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_00328	1121115.AXVN01000028_gene229	2.23e-298	815.0	COG2610@1|root,COG2610@2|Bacteria,1TUM6@1239|Firmicutes,25MFA@186801|Clostridia,3Y1YR@572511|Blautia	186801|Clostridia	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
HGCANGJP_00329	457412.RSAG_02268	0.0	951.0	COG1680@1|root,COG1680@2|Bacteria,1TR9E@1239|Firmicutes,2480P@186801|Clostridia,3WG8D@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HGCANGJP_00330	1121115.AXVN01000028_gene227	1.01e-196	545.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,3XZ7C@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HGCANGJP_00331	1121115.AXVN01000028_gene226	3.46e-53	166.0	2DKC3@1|root,30954@2|Bacteria,1U4FV@1239|Firmicutes,258BV@186801|Clostridia,3Y1WH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
HGCANGJP_00332	1121115.AXVN01000028_gene225	2.4e-41	135.0	COG0425@1|root,COG0425@2|Bacteria,1VKDK@1239|Firmicutes,24RK7@186801|Clostridia,3Y1ZM@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
HGCANGJP_00333	1121115.AXVN01000028_gene224	9.73e-254	696.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,3Y10Q@572511|Blautia	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
HGCANGJP_00334	457412.RSAG_02261	2.47e-272	746.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
HGCANGJP_00335	457412.RSAG_02260	7.27e-211	583.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,3WRR9@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_00336	1121115.AXVN01000028_gene221	0.0	1768.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg
HGCANGJP_00337	457412.RSAG_02257	4.48e-173	483.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,3WMU4@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
HGCANGJP_00338	457412.RSAG_02256	1.5e-194	540.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WJGT@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
HGCANGJP_00339	457412.RSAG_02255	7.15e-164	458.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,3WIU3@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-2 C20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HGCANGJP_00340	1121115.AXVN01000028_gene217	1.46e-118	339.0	COG0614@1|root,COG0614@2|Bacteria,1V6JK@1239|Firmicutes,24KN9@186801|Clostridia,3Y12K@572511|Blautia	186801|Clostridia	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00341	1121115.AXVN01000028_gene216	0.0	942.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,24B8Y@186801|Clostridia,3XYWJ@572511|Blautia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
HGCANGJP_00342	1121115.AXVN01000028_gene215	0.0	1656.0	COG1305@1|root,COG1305@2|Bacteria,1TQGN@1239|Firmicutes,249YH@186801|Clostridia,3Y18M@572511|Blautia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HGCANGJP_00343	457412.RSAG_02251	5.03e-177	493.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
HGCANGJP_00344	457412.RSAG_02250	3.12e-177	494.0	COG1349@1|root,COG1349@2|Bacteria,1TSU1@1239|Firmicutes,25C4E@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, DeoR	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HGCANGJP_00345	457412.RSAG_04635	1.99e-237	652.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HGCANGJP_00346	457412.RSAG_02249	2.42e-236	650.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HGCANGJP_00347	1121115.AXVN01000028_gene210	1.17e-184	517.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZYG@572511|Blautia	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K13891	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1,OppC_N
HGCANGJP_00348	457412.RSAG_02247	5.05e-206	571.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WIW6@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13890	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1
HGCANGJP_00349	457412.RSAG_02246	0.0	1065.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WISX@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	SBP_bac_5
HGCANGJP_00350	457412.RSAG_02245	1.24e-196	546.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WHGA@541000|Ruminococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
HGCANGJP_00351	457412.RSAG_02244	6.78e-61	187.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,3WKTD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
HGCANGJP_00352	457412.RSAG_02243	3.56e-47	151.0	COG1925@1|root,COG1925@2|Bacteria,1VWWX@1239|Firmicutes,252H5@186801|Clostridia	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00353	1121115.AXVN01000028_gene204	2.01e-212	587.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZVT@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_00354	457412.RSAG_02241	0.0	1373.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,3WGWI@541000|Ruminococcaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
HGCANGJP_00355	457412.RSAG_02240	1.17e-308	841.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes	1239|Firmicutes	S	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HGCANGJP_00356	457412.RSAG_02239	5.41e-202	564.0	COG5523@1|root,COG5523@2|Bacteria,1TTE0@1239|Firmicutes,25M7C@186801|Clostridia,3WMQF@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
HGCANGJP_00357	1121115.AXVN01000028_gene200	3.3e-280	767.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYJN@572511|Blautia	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
HGCANGJP_00358	457412.RSAG_02237	2.37e-290	793.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGG4@541000|Ruminococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
HGCANGJP_00359	1121115.AXVN01000028_gene198	1.03e-101	295.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3XZTJ@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
HGCANGJP_00360	1121115.AXVN01000028_gene197	3.29e-234	644.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3XZ5R@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HGCANGJP_00361	1121115.AXVN01000028_gene195	5.49e-203	561.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia,3XZ57@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HGCANGJP_00362	457412.RSAG_02233	1.8e-192	535.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia,3WJQB@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_00363	457412.RSAG_02232	0.0	966.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HGCANGJP_00364	457412.RSAG_02231	0.0	1657.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WGPN@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
HGCANGJP_00365	1121115.AXVN01000125_gene3811	0.0	1006.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3XYYI@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
HGCANGJP_00366	1121115.AXVN01000125_gene3810	6.26e-118	338.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
HGCANGJP_00367	1121115.AXVN01000125_gene3809	3.28e-181	504.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,3XYK1@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisA	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
HGCANGJP_00368	1121115.AXVN01000125_gene3808	8.1e-28	108.0	2EYMV@1|root,33RVF@2|Bacteria,1VSPB@1239|Firmicutes,24XPM@186801|Clostridia,3Y0UE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00369	1121115.AXVN01000186_gene2049	0.0	1475.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_00370	1121115.AXVN01000191_gene1033	9.11e-198	548.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,3XZPS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HGCANGJP_00371	1121115.AXVN01000006_gene2168	8.05e-51	162.0	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes,259R7@186801|Clostridia,3Y0T8@572511|Blautia	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
HGCANGJP_00372	1121115.AXVN01000006_gene2169	1.35e-64	196.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,3Y0NH@572511|Blautia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
HGCANGJP_00373	411459.RUMOBE_00968	1.17e-17	73.9	COG3546@1|root,COG3546@2|Bacteria,1UF7I@1239|Firmicutes,25K8A@186801|Clostridia,3Y21Y@572511|Blautia	186801|Clostridia	P	Manganese containing catalase	-	-	-	-	-	-	-	-	-	-	-	-	Mn_catalase
HGCANGJP_00374	397291.C804_04260	2.42e-26	110.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27KKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HGCANGJP_00375	457412.RSAG_01912	1.25e-54	181.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,3WIAE@541000|Ruminococcaceae	186801|Clostridia	L	PFAM Transposase, Mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HGCANGJP_00376	665950.HMPREF1025_02924	1.96e-309	844.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,27JR7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
HGCANGJP_00377	397287.C807_00302	2.35e-285	781.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,27KR8@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HGCANGJP_00378	1408311.JNJM01000015_gene2587	2.59e-192	554.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1TQQY@1239|Firmicutes,2487W@186801|Clostridia,2PSRT@265975|Oribacterium	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,HTH_Tnp_1,rve,rve_2
HGCANGJP_00379	457412.RSAG_03498	1e-290	793.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3WGYW@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HGCANGJP_00380	457412.RSAG_03436	2.82e-215	597.0	COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,249IK@186801|Clostridia,3WMX0@541000|Ruminococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HGCANGJP_00381	698769.JFBD01000024_gene1884	2.65e-84	253.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00383	457412.RSAG_03284	1.1e-170	476.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia,3WIQF@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HGCANGJP_00384	1121115.AXVN01000021_gene1720	1.81e-132	375.0	2BWC2@1|root,33RSK@2|Bacteria,1VS2M@1239|Firmicutes,24YI2@186801|Clostridia,3Y093@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00385	1121115.AXVN01000021_gene1719	0.0	1594.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3XZN8@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HGCANGJP_00386	1121115.AXVN01000021_gene1718	0.0	1269.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3XYYE@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HGCANGJP_00387	1121115.AXVN01000021_gene1717	5.91e-198	549.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3XYJ8@572511|Blautia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
HGCANGJP_00388	1121115.AXVN01000021_gene1716	2.14e-177	494.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3XZ60@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
HGCANGJP_00389	1121115.AXVN01000021_gene1715	1.4e-204	567.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3XYM3@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
HGCANGJP_00390	457412.RSAG_03291	2.32e-234	645.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,3WI7S@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
HGCANGJP_00391	1121115.AXVN01000021_gene1713	6.51e-140	395.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia,3XZXN@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HGCANGJP_00392	1121115.AXVN01000021_gene1712	0.0	956.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XYX4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	speA_1	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
HGCANGJP_00393	1121115.AXVN01000021_gene1711	1.69e-161	452.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3XYGU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00394	1121115.AXVN01000021_gene1710	8.15e-266	729.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,3XZ9P@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_00395	1121115.AXVN01000021_gene1709	4.37e-285	778.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
HGCANGJP_00396	1121115.AXVN01000021_gene1708	1.35e-300	821.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3XZ1V@572511|Blautia	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HGCANGJP_00397	1121115.AXVN01000021_gene1707	6.42e-112	322.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,3Y00E@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HGCANGJP_00398	457412.RSAG_03298	2.86e-139	393.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HGCANGJP_00399	457412.RSAG_03299	0.0	1090.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
HGCANGJP_00400	1121115.AXVN01000021_gene1704	1.14e-200	557.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,3XZE6@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
HGCANGJP_00401	1121115.AXVN01000021_gene1703	9.78e-156	437.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3XZH1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HGCANGJP_00402	1121115.AXVN01000021_gene1702	1.84e-90	266.0	2EY21@1|root,33RAZ@2|Bacteria,1VSPZ@1239|Firmicutes,24YUD@186801|Clostridia,3Y1ZI@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
HGCANGJP_00403	1121115.AXVN01000021_gene1701	3.77e-217	599.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3XZGB@572511|Blautia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
HGCANGJP_00404	457412.RSAG_03304	0.0	1454.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia,3WGDF@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HGCANGJP_00405	1121115.AXVN01000021_gene1699	5.92e-260	712.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3XZEV@572511|Blautia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
HGCANGJP_00406	1121115.AXVN01000021_gene1698	6.32e-42	137.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,3Y0NB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
HGCANGJP_00407	457412.RSAG_03307	2.61e-259	711.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
HGCANGJP_00408	1121115.AXVN01000021_gene1696	0.0	889.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3XYQ0@572511|Blautia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
HGCANGJP_00409	457412.RSAG_03309	1.37e-21	84.3	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,3WM8B@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
HGCANGJP_00410	457412.RSAG_03310	6.74e-80	237.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3WKGV@541000|Ruminococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
HGCANGJP_00411	457412.RSAG_03311	1.52e-47	151.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
HGCANGJP_00412	457412.RSAG_03312	7.58e-287	786.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
HGCANGJP_00413	1121115.AXVN01000021_gene1693	1.07e-193	540.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3XZCW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
HGCANGJP_00414	1121115.AXVN01000021_gene1692	0.0	878.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3XYJS@572511|Blautia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
HGCANGJP_00415	1121115.AXVN01000021_gene1691	0.0	1219.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3XYJA@572511|Blautia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
HGCANGJP_00416	457412.RSAG_03316	1.69e-171	478.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WIRQ@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
HGCANGJP_00417	457412.RSAG_03317	7.9e-247	679.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_00418	1121115.AXVN01000021_gene1688	1.03e-184	516.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3XYVG@572511|Blautia	186801|Clostridia	N	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
HGCANGJP_00419	457412.RSAG_03319	0.0	943.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,3WIU9@541000|Ruminococcaceae	186801|Clostridia	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
HGCANGJP_00420	1121115.AXVN01000021_gene1686	2.56e-310	861.0	2DN2J@1|root,32V6S@2|Bacteria,1V1QE@1239|Firmicutes,25HR2@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
HGCANGJP_00421	1121115.AXVN01000021_gene1685	1.24e-232	639.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia,3XYQ9@572511|Blautia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HGCANGJP_00422	1121115.AXVN01000021_gene1684	1.32e-176	493.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3XYPE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HGCANGJP_00423	1121115.AXVN01000021_gene1683	1.77e-215	597.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3XZNQ@572511|Blautia	186801|Clostridia	K	chromosome partitioning protein	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HGCANGJP_00424	1121115.AXVN01000021_gene1682	1.11e-113	327.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,3XZYE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
HGCANGJP_00425	1121115.AXVN01000021_gene1681	2.28e-308	840.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3XYK5@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
HGCANGJP_00426	1121115.AXVN01000021_gene1680	3.81e-224	617.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,3XZ0E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
HGCANGJP_00427	457412.RSAG_03327	3.66e-185	515.0	292MS@1|root,2ZQ5N@2|Bacteria,1VRQ1@1239|Firmicutes,24ZSR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00429	500632.CLONEX_02363	1.84e-198	552.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HGCANGJP_00430	518637.EUBIFOR_00832	9.32e-176	491.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,3VPAB@526524|Erysipelotrichia	526524|Erysipelotrichia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HGCANGJP_00431	411461.DORFOR_02722	9.75e-201	557.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
HGCANGJP_00432	411459.RUMOBE_02085	1.55e-229	633.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,3XZD0@572511|Blautia	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HGCANGJP_00433	411461.DORFOR_02720	2.26e-55	173.0	2C39Y@1|root,32RBW@2|Bacteria,1V801@1239|Firmicutes,24JSG@186801|Clostridia,27WV7@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00434	411462.DORLON_01570	5.75e-88	258.0	28PX5@1|root,2ZCH7@2|Bacteria,1V32H@1239|Firmicutes,24GGF@186801|Clostridia,27WRI@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00435	411459.RUMOBE_03454	8.17e-242	663.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3Y087@572511|Blautia	186801|Clostridia	M	COG COG3049 Penicillin V acylase and related amidases	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
HGCANGJP_00436	411469.EUBHAL_01643	5.46e-161	451.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25WDM@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HGCANGJP_00437	585394.RHOM_13755	0.0	1055.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HGCANGJP_00438	411463.EUBVEN_02551	0.0	875.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HGCANGJP_00439	515620.EUBELI_20658	1.69e-93	273.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia,25Y5Y@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00440	411462.DORLON_01574	0.0	959.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,27WIC@189330|Dorea	186801|Clostridia	I	COG COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HGCANGJP_00441	511680.BUTYVIB_02272	5.44e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,4C156@830|Butyrivibrio	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00442	411469.EUBHAL_01647	1.42e-244	672.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,25VS1@186806|Eubacteriaceae	186801|Clostridia	T	CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_00443	411461.DORFOR_03004	1.43e-252	693.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,27WMG@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HGCANGJP_00444	411461.DORFOR_03005	5.15e-130	369.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia,27W1S@189330|Dorea	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HGCANGJP_00445	411462.DORLON_01580	8.65e-53	166.0	COG2856@1|root,COG2856@2|Bacteria,1V1KH@1239|Firmicutes,24GHH@186801|Clostridia,27WZE@189330|Dorea	186801|Clostridia	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
HGCANGJP_00446	1121115.AXVN01000045_gene2064	4.74e-176	492.0	2DM3M@1|root,31JZR@2|Bacteria,1V8CM@1239|Firmicutes,24KFB@186801|Clostridia	186801|Clostridia	M	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HGCANGJP_00447	457412.RSAG_01929	7.84e-70	222.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00449	1121115.AXVN01000057_gene2512	6.78e-42	137.0	2EJPA@1|root,33DE4@2|Bacteria,1VPMV@1239|Firmicutes,24VGY@186801|Clostridia,3Y26U@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00450	1121115.AXVN01000057_gene2511	3.68e-86	269.0	COG5421@1|root,COG5421@2|Bacteria,1UQ6M@1239|Firmicutes,24CF5@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_00451	411461.DORFOR_03170	1.17e-28	103.0	COG2197@1|root,COG2197@2|Bacteria,1UK4C@1239|Firmicutes,24WFK@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00452	445972.ANACOL_00947	1.22e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia,3WIWR@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00453	445972.ANACOL_00948	6.31e-230	635.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3WGIH@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase- DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_00454	445972.ANACOL_00949	2.02e-150	424.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_00455	445972.ANACOL_00953	0.0	1608.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WH8W@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HGCANGJP_00456	1121115.AXVN01000105_gene601	4.89e-91	266.0	COG1595@1|root,COG1595@2|Bacteria,1V0IC@1239|Firmicutes,25DT2@186801|Clostridia,3Y280@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
HGCANGJP_00457	428127.EUBDOL_00132	1.35e-78	233.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,3VRI2@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
HGCANGJP_00458	428127.EUBDOL_00133	1.65e-28	102.0	2FDZB@1|root,345ZK@2|Bacteria,1VZ2U@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00459	556261.HMPREF0240_02064	0.0	1025.0	COG1961@1|root,COG2265@1|root,COG1961@2|Bacteria,COG2265@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,36WA4@31979|Clostridiaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00460	742765.HMPREF9457_01357	9.08e-116	330.0	2CUHA@1|root,33IHG@2|Bacteria,1VPC1@1239|Firmicutes,24W2W@186801|Clostridia,27WQP@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00461	411459.RUMOBE_03443	9.03e-31	108.0	2C7EF@1|root,32Z0F@2|Bacteria,1VFPW@1239|Firmicutes,24VN9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00462	411459.RUMOBE_03444	3.96e-179	499.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HGCANGJP_00463	742765.HMPREF9457_01354	5.54e-212	586.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27W89@189330|Dorea	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HGCANGJP_00464	742765.HMPREF9457_01353	2.7e-216	604.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,27W5K@189330|Dorea	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HGCANGJP_00465	742765.HMPREF9457_01352	1.22e-70	213.0	2BAQE@1|root,3245B@2|Bacteria,1V86A@1239|Firmicutes,24MCZ@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00466	742765.HMPREF9457_01351	1.62e-71	216.0	COG1476@1|root,COG1476@2|Bacteria,1VWA1@1239|Firmicutes,250NE@186801|Clostridia,27X22@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00467	500632.CLONEX_01885	6.04e-27	98.2	2FJSN@1|root,34BFD@2|Bacteria,1W0X9@1239|Firmicutes,253HZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00468	500632.CLONEX_01884	3.05e-146	412.0	COG1595@1|root,COG1595@2|Bacteria,1VRCF@1239|Firmicutes,24HK7@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
HGCANGJP_00469	742765.HMPREF9457_01347	1.06e-91	268.0	COG1595@1|root,COG1595@2|Bacteria,1VRNI@1239|Firmicutes,24ZAW@186801|Clostridia,27X0C@189330|Dorea	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00470	742765.HMPREF9457_01346	0.0	3726.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,25BDZ@186801|Clostridia	186801|Clostridia	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind,Gram_pos_anchor
HGCANGJP_00471	500632.CLONEX_01881	4.25e-27	99.4	2CJ63@1|root,343BH@2|Bacteria,1W0TA@1239|Firmicutes,253UN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00472	742765.HMPREF9457_01344	2.29e-101	295.0	28I1B@1|root,2ZXR7@2|Bacteria,1V4MW@1239|Firmicutes,24E46@186801|Clostridia,27WRH@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
HGCANGJP_00473	500632.CLONEX_01879	1.35e-133	392.0	COG3505@1|root,COG3505@2|Bacteria,1VJMA@1239|Firmicutes,24RRR@186801|Clostridia	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf
HGCANGJP_00474	1280698.AUJS01000107_gene2478	0.0	1206.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
HGCANGJP_00475	658655.HMPREF0988_02972	1.7e-43	149.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,27IXT@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
HGCANGJP_00476	658655.HMPREF0988_02971	0.0	1249.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	HNH,RVT_1
HGCANGJP_00477	742765.HMPREF9457_01343	1.05e-215	609.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,27W8J@189330|Dorea	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
HGCANGJP_00478	742765.HMPREF9457_01342	2.97e-41	135.0	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,24MPR@186801|Clostridia,27X1R@189330|Dorea	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
HGCANGJP_00479	500632.CLONEX_01845	8.06e-199	551.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00480	742765.HMPREF9457_01340	8.83e-81	239.0	COG3451@1|root,COG3451@2|Bacteria,1TTTW@1239|Firmicutes,25MW3@186801|Clostridia,27WZH@189330|Dorea	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
HGCANGJP_00481	742765.HMPREF9457_01339	0.0	1734.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,27W15@189330|Dorea	186801|Clostridia	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
HGCANGJP_00482	500632.CLONEX_01842	1.74e-69	209.0	2C9KX@1|root,33Y5C@2|Bacteria,1VWH2@1239|Firmicutes,2516J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00483	742765.HMPREF9457_01337	0.0	1518.0	COG0791@1|root,COG3064@1|root,COG3584@1|root,COG0791@2|Bacteria,COG3064@2|Bacteria,COG3584@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27WB3@189330|Dorea	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HGCANGJP_00484	742765.HMPREF9457_01336	3.36e-68	207.0	2DVCW@1|root,33VBH@2|Bacteria,1VV1A@1239|Firmicutes,2501N@186801|Clostridia,27X5T@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
HGCANGJP_00485	742765.HMPREF9457_01335	6.99e-144	407.0	COG2433@1|root,COG2433@2|Bacteria,1VTF6@1239|Firmicutes,24ZWY@186801|Clostridia,27WWW@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
HGCANGJP_00486	742765.HMPREF9457_01334	0.0	1396.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24EWC@186801|Clostridia,27W64@189330|Dorea	186801|Clostridia	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim
HGCANGJP_00487	742765.HMPREF9457_01333	0.0	4452.0	COG0553@1|root,COG0827@1|root,COG3170@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3170@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,27WBT@189330|Dorea	186801|Clostridia	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ResIII,SNF2_N
HGCANGJP_00488	742765.HMPREF9457_01320	0.0	3424.0	COG1669@1|root,COG2003@1|root,COG4227@1|root,COG4734@1|root,COG1669@2|Bacteria,COG2003@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,27W0W@189330|Dorea	186801|Clostridia	L	Protein of unknown function (DUF3849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Peptidase_M78,YodL
HGCANGJP_00489	500632.CLONEX_02428	6.09e-53	166.0	2E255@1|root,32XC6@2|Bacteria,1VASU@1239|Firmicutes,24QEA@186801|Clostridia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
HGCANGJP_00490	742765.HMPREF9457_01318	4.95e-196	546.0	COG2003@1|root,COG4734@1|root,COG2003@2|Bacteria,COG4734@2|Bacteria,1UJWR@1239|Firmicutes,25FCK@186801|Clostridia	186801|Clostridia	L	Domain of unknown function (DUF4316)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,YodL
HGCANGJP_00491	742765.HMPREF9457_01317	9.71e-224	616.0	COG4823@1|root,COG4823@2|Bacteria,1UY67@1239|Firmicutes,24CBG@186801|Clostridia	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
HGCANGJP_00492	742765.HMPREF9457_01316	0.0	1003.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia,27W3Q@189330|Dorea	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HGCANGJP_00493	742765.HMPREF9457_01315	4.71e-81	240.0	2C2YH@1|root,31RJ6@2|Bacteria,1V7NS@1239|Firmicutes,24M7H@186801|Clostridia,27WZS@189330|Dorea	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HGCANGJP_00494	411469.EUBHAL_00443	2.5e-122	355.0	COG3208@1|root,COG3208@2|Bacteria,1V5K3@1239|Firmicutes,24HA1@186801|Clostridia,25XNA@186806|Eubacteriaceae	186801|Clostridia	Q	Thioesterase domain	grsT	-	-	-	-	-	-	-	-	-	-	-	Thioesterase
HGCANGJP_00495	759913.SDSE_1357	1.58e-20	85.1	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HGCANGJP_00496	1286170.RORB6_24455	7.7e-47	161.0	2E49B@1|root,32Z53@2|Bacteria,1NFZX@1224|Proteobacteria,1SGG5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00497	877420.ATVW01000028_gene175	2.99e-39	137.0	COG1961@1|root,COG1961@2|Bacteria,1UZM8@1239|Firmicutes,248B3@186801|Clostridia,27JNC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
HGCANGJP_00498	1410626.JHXB01000012_gene2729	8.14e-193	561.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,27IV0@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
HGCANGJP_00499	1410626.JHXB01000012_gene2729	5.18e-25	103.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,27IV0@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
HGCANGJP_00500	1232452.BAIB02000007_gene1632	5.54e-08	55.5	2ER7G@1|root,33IT2@2|Bacteria,1VPWQ@1239|Firmicutes,24RB1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00501	1280698.AUJS01000077_gene3303	1.08e-19	80.5	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,27X8Q@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00502	411461.DORFOR_03054	1.26e-189	528.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24IEC@186801|Clostridia,27VHG@189330|Dorea	186801|Clostridia	V	COG COG4823 Abortive infection bacteriophage resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
HGCANGJP_00503	457412.RSAG_02610	2.17e-35	120.0	2BJ3C@1|root,32DC9@2|Bacteria,1V88B@1239|Firmicutes,24K97@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00504	457412.RSAG_02637	0.0	1044.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
HGCANGJP_00505	1121115.AXVN01000023_gene1809	2.21e-258	708.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3XZ13@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HGCANGJP_00506	1121115.AXVN01000023_gene1808	0.0	887.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZ7Q@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00507	457412.RSAG_02640	3.1e-112	322.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3WJHQ@541000|Ruminococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
HGCANGJP_00509	1121115.AXVN01000023_gene1806	5.23e-256	701.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,3XZVW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00510	1121115.AXVN01000023_gene1805	6.92e-171	476.0	COG1180@1|root,COG1180@2|Bacteria,1V1GP@1239|Firmicutes,24G76@186801|Clostridia,3XZK7@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
HGCANGJP_00511	1121115.AXVN01000023_gene1804	9.89e-199	564.0	COG3584@1|root,COG3883@1|root,COG3584@2|Bacteria,COG3883@2|Bacteria,1UI15@1239|Firmicutes,25EA3@186801|Clostridia,3XZ75@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
HGCANGJP_00512	1121115.AXVN01000023_gene1803	5.64e-59	182.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
HGCANGJP_00513	1121115.AXVN01000023_gene1802	7.41e-255	700.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HGCANGJP_00514	1121115.AXVN01000023_gene1801	5.33e-304	829.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3XZGS@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HGCANGJP_00515	457412.RSAG_02647	0.0	924.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HGCANGJP_00516	457412.RSAG_02648	1.77e-282	772.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3WJJV@541000|Ruminococcaceae	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
HGCANGJP_00517	457412.RSAG_02649	5.45e-232	639.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HGCANGJP_00518	1121115.AXVN01000023_gene1797	4.08e-291	794.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3XYUR@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
HGCANGJP_00520	1121115.AXVN01000023_gene1796	1.62e-296	813.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia,3XZEZ@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
HGCANGJP_00521	1121115.AXVN01000023_gene1795	1.06e-261	716.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,3XZ47@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
HGCANGJP_00522	1121115.AXVN01000023_gene1794	0.0	940.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3XZAQ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
HGCANGJP_00523	457412.RSAG_02654	0.0	1509.0	COG2247@1|root,COG2755@1|root,COG2247@2|Bacteria,COG2755@2|Bacteria,1UKIA@1239|Firmicutes,25FXT@186801|Clostridia,3WMKI@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00524	1121115.AXVN01000023_gene1792	0.0	997.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3XZID@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
HGCANGJP_00525	1121115.AXVN01000023_gene1791	0.0	1581.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,3XYUK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
HGCANGJP_00526	457412.RSAG_02657	1.45e-280	766.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,3WSRX@541000|Ruminococcaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
HGCANGJP_00527	1121115.AXVN01000023_gene1789	5.84e-86	253.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24TCR@186801|Clostridia,3Y0HH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00528	1121115.AXVN01000023_gene1788	7.42e-162	453.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3XZ1X@572511|Blautia	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
HGCANGJP_00529	1121115.AXVN01000023_gene1787	9.1e-54	168.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3Y0NQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
HGCANGJP_00530	1121115.AXVN01000023_gene1786	0.0	1098.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3XZEM@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
HGCANGJP_00531	1121115.AXVN01000023_gene1785	8.21e-92	269.0	2EXFY@1|root,33QS9@2|Bacteria,1VU5K@1239|Firmicutes,24YDE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00532	1121115.AXVN01000023_gene1784	5.23e-256	702.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3XYKG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
HGCANGJP_00533	1121115.AXVN01000023_gene1783	9.42e-122	347.0	2DUBI@1|root,33PTJ@2|Bacteria,1VRWC@1239|Firmicutes,24Y88@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
HGCANGJP_00534	1121115.AXVN01000023_gene1782	5.29e-95	276.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3Y034@572511|Blautia	186801|Clostridia	FG	Psort location Cytoplasmic, score 8.87	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
HGCANGJP_00535	1121115.AXVN01000023_gene1781	1.83e-164	459.0	COG3852@1|root,COG3852@2|Bacteria,1VA7P@1239|Firmicutes,24J8F@186801|Clostridia,3Y29E@572511|Blautia	186801|Clostridia	H	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_00536	457412.RSAG_02667	1.07e-134	382.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,3WJRW@541000|Ruminococcaceae	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
HGCANGJP_00537	457412.RSAG_02668	0.0	949.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia,3WRV5@541000|Ruminococcaceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
HGCANGJP_00538	1121115.AXVN01000023_gene1778	1.24e-103	300.0	2EQ3G@1|root,33HPU@2|Bacteria,1VKDW@1239|Firmicutes,24V35@186801|Clostridia,3Y0MK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
HGCANGJP_00539	1121115.AXVN01000023_gene1777	2.57e-97	283.0	COG1989@1|root,COG1989@2|Bacteria,1VMFT@1239|Firmicutes	1239|Firmicutes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
HGCANGJP_00540	1121115.AXVN01000023_gene1776	6.42e-200	553.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,3Y0C5@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
HGCANGJP_00541	1121115.AXVN01000023_gene1775	0.0	934.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,3XZFX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00542	1121115.AXVN01000023_gene1774	1.49e-32	113.0	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,3Y0UH@572511|Blautia	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
HGCANGJP_00543	457412.RSAG_02674	3.69e-234	645.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,3WJSN@541000|Ruminococcaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HGCANGJP_00544	457412.RSAG_02675	4.1e-176	491.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia,3WJUZ@541000|Ruminococcaceae	186801|Clostridia	U	Flp pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
HGCANGJP_00545	1121115.AXVN01000023_gene1771	1.33e-276	757.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3XZAC@572511|Blautia	186801|Clostridia	U	flp pilus assembly ATPase CpaF	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
HGCANGJP_00546	1121115.AXVN01000023_gene1770	2.37e-249	684.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia,3XZ68@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HGCANGJP_00547	457412.RSAG_02678	7.06e-126	358.0	COG1989@1|root,COG1989@2|Bacteria,1VF54@1239|Firmicutes,24RX8@186801|Clostridia,3WKQB@541000|Ruminococcaceae	186801|Clostridia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
HGCANGJP_00548	457412.RSAG_02679	0.0	1611.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
HGCANGJP_00549	457412.RSAG_02681	9.42e-232	638.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3WGEJ@541000|Ruminococcaceae	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
HGCANGJP_00550	457412.RSAG_02682	0.0	971.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,3WJKE@541000|Ruminococcaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
HGCANGJP_00551	1121115.AXVN01000124_gene3946	6.42e-87	256.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3Y0C9@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
HGCANGJP_00552	1121115.AXVN01000124_gene3947	0.0	911.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3XYVU@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HGCANGJP_00553	1121115.AXVN01000124_gene3948	1.15e-206	572.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3XZ0D@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HGCANGJP_00554	457412.RSAG_02686	0.0	959.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
HGCANGJP_00555	1121115.AXVN01000124_gene3950	8.49e-111	319.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,3Y09Z@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HGCANGJP_00556	457412.RSAG_02688	1.16e-87	260.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WKJC@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
HGCANGJP_00557	1121115.AXVN01000124_gene3952	3.21e-32	113.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y0KZ@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
HGCANGJP_00558	1121115.AXVN01000124_gene3953	1.97e-151	426.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3XZ99@572511|Blautia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HGCANGJP_00559	457412.RSAG_02691	4.81e-160	449.0	COG2755@1|root,COG2755@2|Bacteria,1VT0W@1239|Firmicutes,25BMQ@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HGCANGJP_00560	457412.RSAG_02692	5.51e-195	539.0	COG0454@1|root,COG0456@2|Bacteria,1V37I@1239|Firmicutes,24IZQ@186801|Clostridia,3WNI3@541000|Ruminococcaceae	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_00561	457412.RSAG_03057	1.78e-67	204.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00562	457412.RSAG_04644	5.69e-140	396.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,3WIYQ@541000|Ruminococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
HGCANGJP_00563	457412.RSAG_04643	1.15e-144	408.0	COG2206@1|root,COG2206@2|Bacteria,1UKHX@1239|Firmicutes,25FXF@186801|Clostridia,3WP2X@541000|Ruminococcaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00564	457412.RSAG_03060	1.19e-59	186.0	2EBCY@1|root,335DN@2|Bacteria,1VF9P@1239|Firmicutes,24KM6@186801|Clostridia,3WMHH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00565	457412.RSAG_04725	5.25e-123	351.0	COG1595@1|root,COG1595@2|Bacteria,1V8A6@1239|Firmicutes,24CUW@186801|Clostridia,3WRUA@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_00567	1121115.AXVN01000005_gene2217	0.0	1410.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3XZ98@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HGCANGJP_00568	1121115.AXVN01000005_gene2216	0.0	974.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,3XYWZ@572511|Blautia	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
HGCANGJP_00569	457412.RSAG_03064	0.0	874.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
HGCANGJP_00570	457412.RSAG_03065	2.36e-269	737.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
HGCANGJP_00571	1121115.AXVN01000005_gene2213	5.3e-301	822.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3XYMS@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HGCANGJP_00572	1121115.AXVN01000005_gene2212	1.89e-95	277.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia,3Y0E6@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HGCANGJP_00573	457412.RSAG_03068	1.94e-215	595.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
HGCANGJP_00574	1121115.AXVN01000005_gene2210	1.09e-100	291.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3XZVS@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
HGCANGJP_00575	457412.RSAG_03070	0.0	1102.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3WI74@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
HGCANGJP_00576	457412.RSAG_03071	5.46e-187	519.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
HGCANGJP_00577	1121115.AXVN01000005_gene2207	7.14e-166	464.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3XZUP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
HGCANGJP_00578	1121115.AXVN01000005_gene2206	2.44e-234	649.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3XZ4I@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
HGCANGJP_00579	1121115.AXVN01000005_gene2205	0.0	1176.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3XYMV@572511|Blautia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
HGCANGJP_00580	457412.RSAG_03075	4.2e-240	660.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3WG8N@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
HGCANGJP_00582	457412.RSAG_03076	2.99e-309	842.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3WGZA@541000|Ruminococcaceae	186801|Clostridia	M	peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
HGCANGJP_00583	1469948.JPNB01000001_gene878	1.61e-29	114.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,36GMJ@31979|Clostridiaceae	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
HGCANGJP_00584	1121115.AXVN01000073_gene2023	0.0	1132.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_00585	457412.RSAG_03079	1.05e-160	450.0	2EX9H@1|root,33QK7@2|Bacteria,1VRP0@1239|Firmicutes,24YQ9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00586	1121115.AXVN01000073_gene2021	6.28e-164	459.0	COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,25CHE@186801|Clostridia,3Y0MN@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
HGCANGJP_00587	1121115.AXVN01000073_gene2020	0.0	954.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,24BM3@186801|Clostridia,3Y2A9@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
HGCANGJP_00588	457412.RSAG_03081	1.07e-302	826.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
HGCANGJP_00589	457412.RSAG_03082	7.93e-270	739.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
HGCANGJP_00590	457412.RSAG_03083	7.04e-176	491.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3WH2Z@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
HGCANGJP_00591	1121115.AXVN01000073_gene2016	1.9e-170	475.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3XYZ5@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
HGCANGJP_00592	1121115.AXVN01000073_gene2015	1.12e-116	335.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3XZAV@572511|Blautia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
HGCANGJP_00593	1121115.AXVN01000073_gene2014	1.62e-160	450.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3XZ3X@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HGCANGJP_00594	1121115.AXVN01000073_gene2013	4.26e-177	503.0	2EY3W@1|root,33RCQ@2|Bacteria,1VU3P@1239|Firmicutes,24XPJ@186801|Clostridia,3XZZ1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00595	1121115.AXVN01000073_gene2012	6.48e-136	385.0	COG1102@1|root,COG1102@2|Bacteria,1V4EW@1239|Firmicutes,24IX7@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_00596	1121115.AXVN01000073_gene2011	3.28e-105	304.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3XZU0@572511|Blautia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
HGCANGJP_00597	1121115.AXVN01000073_gene2010	0.0	1465.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3XZBT@572511|Blautia	186801|Clostridia	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
HGCANGJP_00598	457412.RSAG_03091	1.24e-43	142.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,25N7Y@186801|Clostridia,3WM7P@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
HGCANGJP_00599	457412.RSAG_04639	1.19e-190	529.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HGCANGJP_00600	457412.RSAG_03094	0.0	1055.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,3WGJ0@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00601	457412.RSAG_03095	0.0	1111.0	COG1961@1|root,COG1961@2|Bacteria,1V29C@1239|Firmicutes,24GBE@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00602	457412.RSAG_03096	0.0	1059.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00604	457412.RSAG_03098	7.06e-81	239.0	COG2337@1|root,COG2337@2|Bacteria,1TTJP@1239|Firmicutes,25MHP@186801|Clostridia,3WQFT@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
HGCANGJP_00605	457412.RSAG_03100	5.23e-107	308.0	2DBT4@1|root,2ZAVD@2|Bacteria,1V0AF@1239|Firmicutes,24DH6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
HGCANGJP_00606	457412.RSAG_03101	3.04e-36	122.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HTH_34,HxlR
HGCANGJP_00607	457412.RSAG_03102	3.87e-169	471.0	COG2819@1|root,COG2819@2|Bacteria,1TR41@1239|Firmicutes,24EH0@186801|Clostridia,3WS55@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HGCANGJP_00608	457412.RSAG_03103	0.0	993.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,24EGZ@186801|Clostridia,3WI6H@541000|Ruminococcaceae	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
HGCANGJP_00609	457412.RSAG_03104	2.6e-111	319.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,3WJ4Z@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HGCANGJP_00610	457412.RSAG_03106	8.12e-91	265.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WKPB@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
HGCANGJP_00611	457412.RSAG_03413	6.23e-62	190.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00612	457412.RSAG_03414	5.02e-228	628.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WHUP@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
HGCANGJP_00613	411461.DORFOR_00178	1.46e-71	215.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes	1239|Firmicutes	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HGCANGJP_00614	411459.RUMOBE_03498	3.45e-155	436.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,3XZT1@572511|Blautia	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
HGCANGJP_00615	411459.RUMOBE_03497	0.0	1108.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3XZ97@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 9.98	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HGCANGJP_00616	411459.RUMOBE_03496	2.25e-70	212.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,3Y0JZ@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
HGCANGJP_00617	411459.RUMOBE_03495	2.05e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0FX@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HGCANGJP_00618	457412.RSAG_00178	2.23e-202	561.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HGCANGJP_00619	1121115.AXVN01000032_gene385	0.0	1659.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3XYXU@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
HGCANGJP_00620	1121115.AXVN01000032_gene386	5.69e-259	710.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia,3XZZR@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
HGCANGJP_00621	457412.RSAG_00175	2.12e-107	310.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
HGCANGJP_00622	1121115.AXVN01000032_gene388	4.42e-141	397.0	COG5423@1|root,COG5423@2|Bacteria,1V5IN@1239|Firmicutes,24JW6@186801|Clostridia,3XZUH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
HGCANGJP_00623	1121115.AXVN01000032_gene389	1.14e-62	191.0	2DVZX@1|root,33XWD@2|Bacteria,1U4E1@1239|Firmicutes,24VHN@186801|Clostridia,3Y0V7@572511|Blautia	186801|Clostridia	S	COG NOG13846 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	YabP
HGCANGJP_00624	457412.RSAG_00172	1.07e-285	780.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,3WJNK@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
HGCANGJP_00625	1121115.AXVN01000032_gene391	4.1e-227	627.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3XYTC@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
HGCANGJP_00626	457412.RSAG_00169	5.79e-112	322.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
HGCANGJP_00627	457412.RSAG_00167	4.99e-191	531.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
HGCANGJP_00628	1121115.AXVN01000032_gene394	2.05e-42	139.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,3Y0QD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
HGCANGJP_00629	1121115.AXVN01000032_gene395	5e-130	369.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,3XZW4@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
HGCANGJP_00630	457412.RSAG_00164	4.64e-294	803.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HGCANGJP_00631	1121115.AXVN01000032_gene397	2.55e-310	868.0	2DUK2@1|root,33R10@2|Bacteria,1VR47@1239|Firmicutes,24Z5G@186801|Clostridia,3Y0TJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00632	1121115.AXVN01000032_gene398	4.23e-215	593.0	COG2866@1|root,COG2866@2|Bacteria,1UEH5@1239|Firmicutes,25JE5@186801|Clostridia,3Y01R@572511|Blautia	186801|Clostridia	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
HGCANGJP_00633	457412.RSAG_00161	0.0	908.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
HGCANGJP_00634	457412.RSAG_00160	7.15e-312	851.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00635	457412.RSAG_00159	1.66e-67	204.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HGCANGJP_00636	1121115.AXVN01000032_gene402	0.0	1664.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
HGCANGJP_00637	1121115.AXVN01000032_gene403	2.2e-250	687.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,3XZ5Z@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HGCANGJP_00638	457412.RSAG_00449	0.0	1213.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WGJR@541000|Ruminococcaceae	186801|Clostridia	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HGCANGJP_00639	457412.RSAG_00448	0.0	878.0	28N3H@1|root,2ZB96@2|Bacteria,1V5KH@1239|Firmicutes,24I7W@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
HGCANGJP_00640	742765.HMPREF9457_03227	5.78e-46	152.0	2DQDG@1|root,3363Y@2|Bacteria,1VFB3@1239|Firmicutes,24S14@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00641	180332.JTGN01000001_gene4603	4.19e-95	288.0	COG4974@1|root,COG4974@2|Bacteria,1UYB1@1239|Firmicutes,24CA0@186801|Clostridia	186801|Clostridia	L	Phage integrase SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
HGCANGJP_00642	457412.RSAG_00442	3.26e-304	844.0	COG1061@1|root,COG1199@1|root,COG1061@2|Bacteria,COG1199@2|Bacteria,1URXJ@1239|Firmicutes,24FDA@186801|Clostridia	186801|Clostridia	KL	HELICc2	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_2,ResIII
HGCANGJP_00643	457412.RSAG_00441	4.75e-215	594.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HGCANGJP_00644	411469.EUBHAL_02504	0.0	1140.0	COG5635@1|root,COG5635@2|Bacteria,1V23Y@1239|Firmicutes,24H8R@186801|Clostridia	186801|Clostridia	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
HGCANGJP_00645	1046724.KB889908_gene993	0.000947	49.3	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,4659J@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HGCANGJP_00646	411459.RUMOBE_02280	5.68e-40	136.0	COG1396@1|root,COG1396@2|Bacteria,1UK3A@1239|Firmicutes,25FI1@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_00647	1121115.AXVN01000059_gene435	3.5e-67	253.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1V5Z6@1239|Firmicutes,24GM8@186801|Clostridia	186801|Clostridia	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,DUF4062,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8
HGCANGJP_00648	1121115.AXVN01000077_gene2636	3.74e-204	575.0	COG3950@1|root,COG3950@2|Bacteria,1TUXV@1239|Firmicutes,2585Y@186801|Clostridia,3Y246@572511|Blautia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00651	742738.HMPREF9460_01836	3.17e-179	505.0	COG2207@1|root,COG2207@2|Bacteria,1TS8C@1239|Firmicutes,25AZI@186801|Clostridia,268RN@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HGCANGJP_00652	748224.HMPREF9436_01947	6.28e-120	345.0	2BY0N@1|root,2ZA9H@2|Bacteria,1TT24@1239|Firmicutes,24CI6@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Trep_Strep
HGCANGJP_00653	748224.HMPREF9436_01946	3.87e-165	464.0	COG0619@1|root,COG0619@2|Bacteria,1TPUM@1239|Firmicutes,24AGX@186801|Clostridia	186801|Clostridia	P	cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HGCANGJP_00654	411483.FAEPRAA2165_02948	0.0	879.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,3WGDV@541000|Ruminococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HGCANGJP_00655	658659.HMPREF0983_01740	0.0	1112.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VPEH@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
HGCANGJP_00656	658659.HMPREF0983_01739	0.0	1080.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VPKR@526524|Erysipelotrichia	526524|Erysipelotrichia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
HGCANGJP_00658	1232453.BAIF02000019_gene3940	4.47e-116	334.0	COG1309@1|root,COG1309@2|Bacteria,1V2EH@1239|Firmicutes,24H5Z@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HGCANGJP_00659	1232453.BAIF02000019_gene3941	2.64e-126	361.0	COG0500@1|root,COG2226@2|Bacteria,1TR4Y@1239|Firmicutes,24DHJ@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HGCANGJP_00660	1232453.BAIF02000019_gene3944	1.4e-137	389.0	COG0500@1|root,COG2226@2|Bacteria,1TVU2@1239|Firmicutes,24AIJ@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
HGCANGJP_00661	1232453.BAIF02000019_gene3945	2.94e-213	590.0	COG0657@1|root,COG0657@2|Bacteria,1UZG9@1239|Firmicutes,24EPJ@186801|Clostridia	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
HGCANGJP_00662	1232453.BAIF02000019_gene3946	3.07e-33	121.0	COG0500@1|root,COG2226@2|Bacteria,1UVT3@1239|Firmicutes,24G51@186801|Clostridia,26CH8@186813|unclassified Clostridiales	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
HGCANGJP_00663	1232453.BAIF02000019_gene3948	4.74e-08	52.8	28NZK@1|root,30VZ5@2|Bacteria,1VBXY@1239|Firmicutes,24N0D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00664	1232453.BAIF02000019_gene3949	2.47e-183	511.0	COG3315@1|root,COG3315@2|Bacteria,1TR1Q@1239|Firmicutes,24BWW@186801|Clostridia	186801|Clostridia	Q	COG COG3315 O-Methyltransferase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	LCM
HGCANGJP_00665	1280679.ATVX01000015_gene640	2.45e-13	68.9	COG1893@1|root,COG1893@2|Bacteria,1V4R7@1239|Firmicutes,25BA6@186801|Clostridia,4C25H@830|Butyrivibrio	186801|Clostridia	H	Ketopantoate reductase PanE/ApbA	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA
HGCANGJP_00666	1121115.AXVN01000200_gene607	2.18e-88	263.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
HGCANGJP_00667	1226325.HMPREF1548_06046	2.34e-25	94.7	2FFQM@1|root,347MX@2|Bacteria,1VZ7D@1239|Firmicutes,24WVT@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
HGCANGJP_00668	1226325.HMPREF1548_06048	2.74e-50	159.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia,36PDP@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
HGCANGJP_00669	742741.HMPREF9475_01934	3.1e-91	268.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,25FBE@186801|Clostridia,2240K@1506553|Lachnoclostridium	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
HGCANGJP_00670	742738.HMPREF9460_03118	5.73e-239	656.0	COG0820@1|root,COG0820@2|Bacteria,1TQDD@1239|Firmicutes,24AXB@186801|Clostridia,26A0E@186813|unclassified Clostridiales	186801|Clostridia	H	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
HGCANGJP_00671	1226322.HMPREF1545_02565	5.17e-73	219.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,25BHS@186801|Clostridia,2N8I8@216572|Oscillospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_00672	1226322.HMPREF1545_02564	7.74e-68	206.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,2N8QM@216572|Oscillospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HGCANGJP_00673	552396.HMPREF0863_02717	3.37e-306	836.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,3VNWF@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HGCANGJP_00674	176279.SERP1585	0.0	975.0	COG1670@1|root,COG3173@1|root,COG1670@2|Bacteria,COG3173@2|Bacteria,1V1G0@1239|Firmicutes,4I3EZ@91061|Bacilli,4GYHN@90964|Staphylococcaceae	91061|Bacilli	F	Involved in resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region. The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides	-	-	2.3.1.82,2.7.1.190	ko:K19883	-	-	R11229	RC00002,RC00078	ko00000,ko01000,ko01504	-	-	-	APH,Acetyltransf_8
HGCANGJP_00675	1280.SAXN108_2178	1.92e-90	265.0	COG0454@1|root,COG0456@2|Bacteria,1TXSN@1239|Firmicutes,4I6UP@91061|Bacilli,4GZ1F@90964|Staphylococcaceae	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_00676	1234679.BN424_1079	2.14e-279	764.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HB0P@91061|Bacilli,27FPR@186828|Carnobacteriaceae	91061|Bacilli	L	L COG3328 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HGCANGJP_00678	1507.HMPREF0262_01054	2.13e-40	137.0	COG1476@1|root,COG1476@2|Bacteria,1UHV0@1239|Firmicutes,25E3M@186801|Clostridia,36UHF@31979|Clostridiaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_00679	877411.JMMA01000002_gene3035	1.93e-23	97.1	2EJ5W@1|root,33CX3@2|Bacteria,1V8TH@1239|Firmicutes,24QD4@186801|Clostridia,3WJ2W@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00680	1226325.HMPREF1548_06057	9.1e-33	114.0	2E9U2@1|root,33400@2|Bacteria,1VGEQ@1239|Firmicutes,24RRM@186801|Clostridia,36SH4@31979|Clostridiaceae	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
HGCANGJP_00681	742741.HMPREF9475_01927	0.0	1847.0	COG2003@1|root,COG4227@1|root,COG4734@1|root,COG2003@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,21ZD6@1506553|Lachnoclostridium	186801|Clostridia	L	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF4316,Peptidase_M78,YodL
HGCANGJP_00682	742741.HMPREF9475_01925	0.0	1344.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,21Z9P@1506553|Lachnoclostridium	186801|Clostridia	L	Bacterial DNA topoisomeraes I ATP-binding domain	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
HGCANGJP_00683	742741.HMPREF9475_01924	3.44e-140	399.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,24AUT@186801|Clostridia,21ZXN@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366,SH3_3
HGCANGJP_00684	1226325.HMPREF1548_06063	1.98e-49	157.0	2AF03@1|root,330GW@2|Bacteria,1VHVV@1239|Firmicutes,24KKT@186801|Clostridia,36W0D@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
HGCANGJP_00685	1226325.HMPREF1548_06064	0.0	1217.0	COG0791@1|root,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,36H24@31979|Clostridiaceae	186801|Clostridia	M	NlpC P60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HGCANGJP_00686	1226322.HMPREF1545_02555	2.09e-245	672.0	COG0863@1|root,COG0863@2|Bacteria,1TR56@1239|Firmicutes,248NR@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	cfr9IM	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
HGCANGJP_00687	552396.HMPREF0863_02709	0.0	1547.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,3VPNT@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,PrgI
HGCANGJP_00688	1226322.HMPREF1545_02553	4.11e-82	243.0	28PED@1|root,2ZC60@2|Bacteria,1V1JX@1239|Firmicutes,24G6H@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
HGCANGJP_00689	1226322.HMPREF1545_02552	1.67e-226	622.0	COG1032@1|root,COG1032@2|Bacteria,1TRY3@1239|Firmicutes,249Q1@186801|Clostridia,2N82M@216572|Oscillospiraceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00690	552396.HMPREF0863_02706	9.4e-197	546.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,3VP2T@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00691	1121115.AXVN01000013_gene3190	0.0	1065.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00692	1121115.AXVN01000013_gene3191	1.24e-39	131.0	2DNP9@1|root,32YE1@2|Bacteria,1VEMU@1239|Firmicutes,24N4S@186801|Clostridia,3Y0IW@572511|Blautia	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
HGCANGJP_00693	1121115.AXVN01000013_gene3192	6.01e-212	584.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3XZBX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HGCANGJP_00694	1121115.AXVN01000013_gene3193	4.49e-179	498.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,3Y084@572511|Blautia	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HGCANGJP_00695	658086.HMPREF0994_06819	0.0	1066.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia,27IJ8@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HGCANGJP_00696	1121115.AXVN01000013_gene3196	1.18e-86	255.0	2C2YH@1|root,2ZBKZ@2|Bacteria,1V3N8@1239|Firmicutes,24FYJ@186801|Clostridia,3Y082@572511|Blautia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HGCANGJP_00697	411902.CLOBOL_04284	1.6e-108	313.0	2EWMS@1|root,30FQV@2|Bacteria,1UEFU@1239|Firmicutes,25JCN@186801|Clostridia,2223E@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00698	1121115.AXVN01000013_gene3197	9.71e-74	220.0	2F2W4@1|root,33VRY@2|Bacteria,1VW1H@1239|Firmicutes,250T7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00699	742733.HMPREF9469_01266	4.09e-26	95.9	2CDEH@1|root,32YRT@2|Bacteria,1VFMR@1239|Firmicutes,24QUE@186801|Clostridia,2216Y@1506553|Lachnoclostridium	186801|Clostridia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
HGCANGJP_00700	1226325.HMPREF1548_03082	4.53e-47	156.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,36NGV@31979|Clostridiaceae	186801|Clostridia	U	TraM recognition site of TraD and TraG	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
HGCANGJP_00701	500632.CLONEX_01867	0.0	1299.0	2EMVJ@1|root,33FHT@2|Bacteria,1VND6@1239|Firmicutes,24UZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00702	658088.HMPREF0987_00276	1.45e-80	239.0	2F0Z1@1|root,33U0P@2|Bacteria,1VUKM@1239|Firmicutes,250HF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00703	500632.CLONEX_01869	0.0	1102.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00704	903814.ELI_0219	2.77e-30	107.0	2E5XN@1|root,330MH@2|Bacteria,1VJZ8@1239|Firmicutes,24S7N@186801|Clostridia,25Y03@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00705	903814.ELI_0218	0.0	910.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,25VCP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VirE
HGCANGJP_00706	500632.CLONEX_01872	3.56e-167	466.0	COG0358@1|root,COG0358@2|Bacteria,1TSS5@1239|Firmicutes,25C96@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
HGCANGJP_00707	500632.CLONEX_01873	1.06e-274	758.0	28JIM@1|root,2Z9BV@2|Bacteria,1TRP9@1239|Firmicutes,24DM5@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00708	500632.CLONEX_01874	3.41e-65	198.0	2AZMT@1|root,31RWJ@2|Bacteria,1V8FY@1239|Firmicutes,24JSC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00709	500632.CLONEX_01875	7.04e-63	192.0	2C0W3@1|root,32R7Q@2|Bacteria,1V8KS@1239|Firmicutes,24JJI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00710	500632.CLONEX_01877	5.16e-183	512.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_00711	500632.CLONEX_01878	2.1e-91	267.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,25CQN@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_00712	1226325.HMPREF1548_03082	2.63e-110	321.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,36NGV@31979|Clostridiaceae	186801|Clostridia	U	TraM recognition site of TraD and TraG	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
HGCANGJP_00713	1232453.BAIF02000006_gene1452	3.49e-84	248.0	28NST@1|root,2ZBRP@2|Bacteria,1V1QP@1239|Firmicutes,24FUC@186801|Clostridia,26BAD@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00714	552396.HMPREF0863_00450	6.68e-35	119.0	2E8ED@1|root,32T9Y@2|Bacteria,1VDIA@1239|Firmicutes	1239|Firmicutes	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
HGCANGJP_00715	1121115.AXVN01000013_gene3202	3.42e-199	552.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3XZBX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HGCANGJP_00716	657322.FPR_00580	2.03e-165	463.0	COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,249Q8@186801|Clostridia,3WK4V@541000|Ruminococcaceae	186801|Clostridia	L	Phage replisome organizer, N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
HGCANGJP_00717	1121115.AXVN01000013_gene3205	5.31e-58	179.0	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,24PQZ@186801|Clostridia	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
HGCANGJP_00718	1121115.AXVN01000013_gene3206	1.23e-49	159.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia,3Y0QQ@572511|Blautia	186801|Clostridia	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
HGCANGJP_00719	908340.HMPREF9406_3895	0.0	930.0	COG0507@1|root,COG1196@1|root,COG0507@2|Bacteria,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,36DJZ@31979|Clostridiaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HGCANGJP_00720	1232453.BAIF02000021_gene4380	1.61e-51	165.0	2BAGF@1|root,323X1@2|Bacteria,1V6WJ@1239|Firmicutes,24JBD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
HGCANGJP_00721	1121115.AXVN01000013_gene3209	8.96e-102	295.0	COG1595@1|root,COG1595@2|Bacteria,1VBQS@1239|Firmicutes,247JZ@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
HGCANGJP_00722	552396.HMPREF0863_00459	1.41e-103	299.0	COG1595@1|root,COG1595@2|Bacteria,1TRYZ@1239|Firmicutes	1239|Firmicutes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
HGCANGJP_00723	552396.HMPREF0863_00460	1.52e-94	275.0	COG1595@1|root,COG1595@2|Bacteria,1V70T@1239|Firmicutes	1239|Firmicutes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2,UPF0122
HGCANGJP_00724	585394.RHOM_15550	1.51e-206	572.0	COG0642@1|root,COG2205@2|Bacteria,1UZ8S@1239|Firmicutes,25E8V@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_00725	585394.RHOM_15555	2.29e-183	511.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
HGCANGJP_00726	585394.RHOM_15560	4.22e-214	592.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990,ko:K19309	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC_tran
HGCANGJP_00727	585394.RHOM_15565	2.31e-155	436.0	COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,24J6Y@186801|Clostridia	186801|Clostridia	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00728	585394.RHOM_15570	4.18e-38	127.0	COG2909@1|root,COG2909@2|Bacteria,1VGPU@1239|Firmicutes,24RRJ@186801|Clostridia	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HGCANGJP_00729	500632.CLONEX_01765	4.76e-84	248.0	COG1396@1|root,COG1396@2|Bacteria,1V331@1239|Firmicutes,24G00@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
HGCANGJP_00730	1280698.AUJS01000002_gene2702	1.03e-65	199.0	2E6DS@1|root,3311B@2|Bacteria,1VEV3@1239|Firmicutes,25931@186801|Clostridia,27VXS@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00731	742741.HMPREF9475_02785	3.16e-73	220.0	2C5R4@1|root,30EV5@2|Bacteria,1V4TD@1239|Firmicutes,25CQK@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_00732	1507.HMPREF0262_00536	3.67e-95	295.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,36DU1@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_00734	457412.RSAG_00907	1.28e-205	570.0	COG0679@1|root,COG0679@2|Bacteria,1TRAI@1239|Firmicutes,24HU9@186801|Clostridia,3WPNA@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HGCANGJP_00735	457412.RSAG_00908	4.89e-211	584.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,3WI1Q@541000|Ruminococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HGCANGJP_00736	457412.RSAG_00909	3.68e-171	478.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_00737	457412.RSAG_00910	0.0	883.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00738	742765.HMPREF9457_01244	1.67e-185	516.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,248UQ@186801|Clostridia	186801|Clostridia	S	Belongs to the D-glutamate cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1445
HGCANGJP_00739	1121115.AXVN01000061_gene498	1.02e-167	478.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3XYMM@572511|Blautia	186801|Clostridia	S	N-methylation of lysine residues in flagellin	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
HGCANGJP_00740	1410626.JHXB01000024_gene404	7.9e-26	106.0	2CHC9@1|root,346TJ@2|Bacteria,1VYZJ@1239|Firmicutes,253CK@186801|Clostridia,27QIU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00741	457412.RSAG_00912	9.31e-17	74.7	COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,248RZ@186801|Clostridia,3WHGZ@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186,DUF5131
HGCANGJP_00742	457412.RSAG_00913	6.78e-136	384.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,3WK2W@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
HGCANGJP_00743	457412.RSAG_04704	7.61e-95	280.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia,3WIG0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00744	457412.RSAG_00916	2.18e-211	583.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia,3WSCK@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HGCANGJP_00747	457412.RSAG_00919	8.42e-102	295.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
HGCANGJP_00748	457412.RSAG_00920	1.94e-245	673.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,24E6T@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
HGCANGJP_00749	457412.RSAG_00921	0.0	1484.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
HGCANGJP_00750	1121115.AXVN01000002_gene1364	1.79e-57	188.0	2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24UU3@186801|Clostridia,3Y0P6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00751	457412.RSAG_00923	0.0	1302.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
HGCANGJP_00752	457412.RSAG_00924	0.0	1044.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
HGCANGJP_00753	1121115.AXVN01000002_gene1361	2.47e-77	231.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,3Y05W@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
HGCANGJP_00754	457412.RSAG_00926	6.24e-39	129.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
HGCANGJP_00755	1121115.AXVN01000002_gene1360	2.15e-81	241.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,3Y06K@572511|Blautia	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
HGCANGJP_00756	457412.RSAG_00929	4.8e-229	632.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,3WM1N@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
HGCANGJP_00757	457412.RSAG_00930	1.18e-66	202.0	2CSSR@1|root,33IRN@2|Bacteria,1VG13@1239|Firmicutes,258FD@186801|Clostridia,3WMK4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00758	1121115.AXVN01000002_gene1357	4.04e-108	311.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,3XZUN@572511|Blautia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HGCANGJP_00759	1121115.AXVN01000002_gene1356	0.0	942.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,3XYMX@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
HGCANGJP_00760	1121115.AXVN01000002_gene1355	1.68e-310	848.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3XYN1@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
HGCANGJP_00761	1121115.AXVN01000002_gene1354	0.0	1464.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3XYUZ@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
HGCANGJP_00762	1121115.AXVN01000002_gene1353	2.16e-84	249.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,3Y0AS@572511|Blautia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
HGCANGJP_00763	1121115.AXVN01000002_gene1352	3.72e-238	655.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3XZK8@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
HGCANGJP_00764	457412.RSAG_00937	9.43e-132	375.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
HGCANGJP_00765	1121115.AXVN01000002_gene1350	5.72e-195	540.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3XZFG@572511|Blautia	186801|Clostridia	C	F420-non-reducing hydrogenase	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
HGCANGJP_00766	1121115.AXVN01000002_gene1349	9.51e-122	348.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3XYQD@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
HGCANGJP_00767	1121115.AXVN01000002_gene1348	2.48e-162	455.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3XYKR@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
HGCANGJP_00768	1121115.AXVN01000002_gene1347	4.29e-128	365.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3XZTQ@572511|Blautia	186801|Clostridia	P	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
HGCANGJP_00769	1121115.AXVN01000002_gene1346	5.22e-229	631.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3XYSH@572511|Blautia	186801|Clostridia	C	Electron transport complex	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
HGCANGJP_00770	1121115.AXVN01000002_gene1345	0.0	876.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XYXE@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
HGCANGJP_00771	457412.RSAG_00944	1.49e-252	692.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,3WPXI@541000|Ruminococcaceae	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
HGCANGJP_00772	1121115.AXVN01000002_gene1343	6.93e-154	432.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,25D1G@186801|Clostridia	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
HGCANGJP_00773	1121115.AXVN01000002_gene1342	2.15e-63	194.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
HGCANGJP_00774	1121115.AXVN01000002_gene1341	0.0	5911.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
HGCANGJP_00775	457412.RSAG_00948	0.0	1103.0	COG0534@1|root,COG0534@2|Bacteria,1V10K@1239|Firmicutes,24CIC@186801|Clostridia,3WJM8@541000|Ruminococcaceae	186801|Clostridia	TV	MatE	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MatE
HGCANGJP_00776	1121115.AXVN01000002_gene1339	0.0	973.0	COG1520@1|root,COG1520@2|Bacteria,1TQ7F@1239|Firmicutes,249BV@186801|Clostridia,3Y109@572511|Blautia	186801|Clostridia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
HGCANGJP_00777	1121115.AXVN01000002_gene1338	3.96e-89	261.0	2CJZW@1|root,30J0V@2|Bacteria,1UVFN@1239|Firmicutes,2596T@186801|Clostridia,3Y21H@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00779	457412.RSAG_00951	9.55e-206	568.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3WGB9@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
HGCANGJP_00781	457412.RSAG_04701	2.67e-101	293.0	2EB8P@1|root,33598@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00782	457412.RSAG_00953	4.19e-171	478.0	COG4916@1|root,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
HGCANGJP_00783	457412.RSAG_00969	4.32e-17	73.9	2EJPA@1|root,33DE4@2|Bacteria,1VPMV@1239|Firmicutes,24VGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00784	457412.RSAG_00955	4.23e-81	255.0	COG5421@1|root,COG5421@2|Bacteria,1UHBN@1239|Firmicutes,249CH@186801|Clostridia,3WPID@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_00785	1121115.AXVN01000006_gene2163	4.19e-265	728.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3XYUT@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HGCANGJP_00786	1121115.AXVN01000006_gene2162	1.02e-46	150.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3Y0HG@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
HGCANGJP_00787	457412.RSAG_00781	4.92e-213	589.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
HGCANGJP_00788	457412.RSAG_00780	1.43e-166	466.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
HGCANGJP_00789	457412.RSAG_00779	6.9e-298	812.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
HGCANGJP_00790	457412.RSAG_00778	4.68e-99	288.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3WJAY@541000|Ruminococcaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
HGCANGJP_00791	1121115.AXVN01000006_gene2157	1.43e-95	278.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3Y04Q@572511|Blautia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
HGCANGJP_00792	1121115.AXVN01000006_gene2156	0.0	889.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3XZMB@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HGCANGJP_00793	1121115.AXVN01000006_gene2155	0.0	1122.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3XYX8@572511|Blautia	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
HGCANGJP_00794	1121115.AXVN01000006_gene2154	0.0	976.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3XZIU@572511|Blautia	186801|Clostridia	H	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
HGCANGJP_00795	1121115.AXVN01000006_gene2153	0.0	1158.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,3XYTS@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HGCANGJP_00796	1121115.AXVN01000006_gene2152	2.8e-135	382.0	COG2091@1|root,COG2091@2|Bacteria,1UFUD@1239|Firmicutes,25MRV@186801|Clostridia,3Y03Q@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
HGCANGJP_00797	1121115.AXVN01000006_gene2151	1.28e-265	727.0	COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,24K83@186801|Clostridia,3Y0X1@572511|Blautia	186801|Clostridia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00798	457412.RSAG_00770	4.03e-240	659.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
HGCANGJP_00799	1121115.AXVN01000006_gene2149	4.35e-120	343.0	2CEWW@1|root,3181X@2|Bacteria,1U7IP@1239|Firmicutes,2590I@186801|Clostridia,3Y0MY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
HGCANGJP_00800	457412.RSAG_00768	9.49e-35	119.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HGCANGJP_00801	1121115.AXVN01000006_gene2147	1.25e-80	240.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,3Y0FF@572511|Blautia	186801|Clostridia	S	COG NOG13205 non supervised orthologous group	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
HGCANGJP_00802	457412.RSAG_00766	1.86e-269	740.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3WITJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
HGCANGJP_00803	457412.RSAG_00765	4.38e-121	347.0	29TPZ@1|root,30EY4@2|Bacteria,1UD4F@1239|Firmicutes,2591T@186801|Clostridia,3WMKP@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AF (Spore_III_AF)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AF
HGCANGJP_00804	1121115.AXVN01000006_gene2144	5.3e-50	159.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,3Y0J8@572511|Blautia	186801|Clostridia	S	COG NOG11553 non supervised orthologous group	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
HGCANGJP_00805	457412.RSAG_00763	1.4e-159	449.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
HGCANGJP_00806	457412.RSAG_00762	0.0	1051.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,3WGUR@541000|Ruminococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
HGCANGJP_00807	1121115.AXVN01000006_gene2141	4.65e-78	233.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3Y075@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
HGCANGJP_00808	1121115.AXVN01000006_gene2140	5.6e-73	219.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3Y08R@572511|Blautia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
HGCANGJP_00809	1121115.AXVN01000006_gene2139	8.27e-273	749.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3XZS9@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
HGCANGJP_00810	1121115.AXVN01000006_gene2138	2.03e-47	152.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,3Y0QF@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
HGCANGJP_00811	457412.RSAG_00757	2.94e-204	566.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
HGCANGJP_00812	1121115.AXVN01000006_gene2136	0.0	1233.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3XYQF@572511|Blautia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
HGCANGJP_00813	457412.RSAG_00755	5.27e-194	538.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
HGCANGJP_00814	1121115.AXVN01000006_gene2134	5.1e-205	567.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3XZAI@572511|Blautia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
HGCANGJP_00815	457412.RSAG_00753	6.17e-99	288.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
HGCANGJP_00816	457412.RSAG_00752	0.0	1030.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
HGCANGJP_00817	1121115.AXVN01000006_gene2131	2.19e-291	795.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,3XZ8A@572511|Blautia	186801|Clostridia	T	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
HGCANGJP_00818	457412.RSAG_00750	6.11e-188	522.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,3WGU4@541000|Ruminococcaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
HGCANGJP_00819	1121115.AXVN01000006_gene2129	0.0	1001.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
HGCANGJP_00820	1121115.AXVN01000006_gene2128	3.38e-251	689.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3XZ9Q@572511|Blautia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
HGCANGJP_00821	457412.RSAG_00747	4.55e-131	372.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,3WM72@541000|Ruminococcaceae	186801|Clostridia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
HGCANGJP_00822	457412.RSAG_00746	2.79e-299	825.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
HGCANGJP_00823	457412.RSAG_00744	6.99e-136	385.0	2DUTP@1|root,33S73@2|Bacteria,1US3V@1239|Firmicutes,25A29@186801|Clostridia,3WR2A@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00824	457412.RSAG_00743	3.08e-210	581.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
HGCANGJP_00825	1121115.AXVN01000006_gene2123	2.12e-253	694.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3XYX3@572511|Blautia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
HGCANGJP_00826	457412.RSAG_00741	5.78e-304	830.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WGTJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HGCANGJP_00827	1121115.AXVN01000006_gene2121	1.09e-104	303.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0AW@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HGCANGJP_00828	1121115.AXVN01000006_gene2120	2.73e-284	776.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HGCANGJP_00829	1121115.AXVN01000006_gene2119	6.48e-104	300.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3XZVP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
HGCANGJP_00830	457412.RSAG_00737	0.0	1590.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WHCP@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
HGCANGJP_00831	457412.RSAG_04756	0.0	1309.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WH4U@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
HGCANGJP_00832	457412.RSAG_00734	5.75e-204	563.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,3WHRZ@541000|Ruminococcaceae	186801|Clostridia	E	histidinol phosphate phosphatase HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
HGCANGJP_00833	1121115.AXVN01000006_gene2115	2.84e-240	660.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
HGCANGJP_00834	457412.RSAG_00732	1.86e-288	787.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
HGCANGJP_00835	1121115.AXVN01000006_gene2113	9.02e-176	490.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3XYGS@572511|Blautia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
HGCANGJP_00836	1121115.AXVN01000006_gene2112	3.11e-291	794.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZS4@572511|Blautia	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
HGCANGJP_00837	1121115.AXVN01000006_gene2111	1.83e-116	332.0	COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,24JT6@186801|Clostridia,3Y06X@572511|Blautia	186801|Clostridia	K	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_00838	1121115.AXVN01000006_gene2110	0.0	918.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3XZRA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
HGCANGJP_00839	457412.RSAG_00727	1.15e-39	131.0	COG3655@1|root,COG3655@2|Bacteria,1TU95@1239|Firmicutes,25804@186801|Clostridia,3WQZ7@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
HGCANGJP_00840	457412.RSAG_00726	3.32e-56	174.0	2C1AP@1|root,33ZCD@2|Bacteria,1VYDT@1239|Firmicutes,2529X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00841	1121115.AXVN01000006_gene2107	2.03e-307	838.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XZMY@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
HGCANGJP_00842	457412.RSAG_00723	0.0	1036.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
HGCANGJP_00843	1121115.AXVN01000006_gene2105	4.41e-305	833.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZQ9@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00844	457412.RSAG_00721	0.0	1049.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WH27@541000|Ruminococcaceae	186801|Clostridia	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HGCANGJP_00845	1121115.AXVN01000006_gene2103	2.48e-44	145.0	2DWAP@1|root,33ZBJ@2|Bacteria,1VWWH@1239|Firmicutes,25203@186801|Clostridia,3Y23P@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
HGCANGJP_00846	457412.RSAG_00719	6.62e-257	704.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
HGCANGJP_00847	1121115.AXVN01000061_gene485	9.97e-245	672.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,3XYRU@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HGCANGJP_00848	1121115.AXVN01000061_gene486	3.55e-162	454.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3Y0B6@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
HGCANGJP_00849	457412.RSAG_00716	3.04e-156	438.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24EFS@186801|Clostridia,3WRPD@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00850	457412.RSAG_00715	0.0	1457.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3WGKN@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
HGCANGJP_00851	1121115.AXVN01000061_gene489	7.23e-85	250.0	2DRY9@1|root,33DNC@2|Bacteria,1VJXZ@1239|Firmicutes,25NY6@186801|Clostridia,3Y0SG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00852	1121115.AXVN01000061_gene490	6.17e-165	460.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia,3XZVI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
HGCANGJP_00853	457412.RSAG_00712	8.73e-191	529.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia,3WJ5M@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
HGCANGJP_00854	1121115.AXVN01000061_gene492	0.0	1608.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3Y0G0@572511|Blautia	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
HGCANGJP_00855	1121115.AXVN01000061_gene493	0.0	1827.0	COG3459@1|root,COG3459@2|Bacteria,1UYFP@1239|Firmicutes,24A8A@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
HGCANGJP_00856	457412.RSAG_00709	0.0	924.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
HGCANGJP_00857	1121115.AXVN01000061_gene495	6.23e-217	600.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_00858	1121115.AXVN01000061_gene496	2.71e-177	496.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_00859	1121115.AXVN01000061_gene497	0.0	1636.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3Y07X@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_00860	1121115.AXVN01000061_gene498	3.58e-308	837.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3XYMM@572511|Blautia	186801|Clostridia	S	N-methylation of lysine residues in flagellin	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
HGCANGJP_00861	457412.RSAG_00704	6.22e-207	571.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3WIGP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
HGCANGJP_00862	1121115.AXVN01000061_gene500	0.0	1483.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,3XZ5G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
HGCANGJP_00863	457412.RSAG_00702	1.83e-259	710.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
HGCANGJP_00864	1121115.AXVN01000043_gene3360	0.0	962.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3XYH4@572511|Blautia	186801|Clostridia	O	AAA domain (dynein-related subfamily)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
HGCANGJP_00865	457412.RSAG_00700	1.84e-261	717.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WG7W@541000|Ruminococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
HGCANGJP_00866	457412.RSAG_00699	1.83e-149	421.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
HGCANGJP_00867	457412.RSAG_00698	9.66e-292	796.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WGA9@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
HGCANGJP_00868	1121115.AXVN01000043_gene3364	5.25e-106	306.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,3XZWN@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
HGCANGJP_00869	457412.RSAG_00696	1.09e-249	685.0	COG0564@1|root,COG0564@2|Bacteria,1VS66@1239|Firmicutes,25M7T@186801|Clostridia,3WP3U@541000|Ruminococcaceae	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
HGCANGJP_00870	457412.RSAG_00695	5.18e-222	612.0	COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,249UK@186801|Clostridia,3WGSB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
HGCANGJP_00871	1121115.AXVN01000043_gene3367	0.0	1068.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3XYJY@572511|Blautia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
HGCANGJP_00872	1121115.AXVN01000043_gene3368	7.09e-155	437.0	2E03H@1|root,333DZ@2|Bacteria,1VJ8Q@1239|Firmicutes,24RNP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00873	1121115.AXVN01000043_gene3369	1.47e-76	228.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,3Y07N@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
HGCANGJP_00874	457412.RSAG_00691	6.73e-243	667.0	COG4637@1|root,COG4637@2|Bacteria,1V0EX@1239|Firmicutes,24B14@186801|Clostridia,3WIPF@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
HGCANGJP_00875	1121115.AXVN01000043_gene3372	3.02e-111	319.0	COG4728@1|root,COG4728@2|Bacteria,1UQCA@1239|Firmicutes,24HXT@186801|Clostridia,3Y0R7@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DUF1653
HGCANGJP_00876	1121115.AXVN01000043_gene3373	5.72e-121	345.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,3Y05Q@572511|Blautia	186801|Clostridia	Q	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
HGCANGJP_00877	1121115.AXVN01000043_gene3374	2.01e-141	399.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3XZZD@572511|Blautia	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
HGCANGJP_00878	1121115.AXVN01000043_gene3375	1.57e-116	337.0	COG2227@1|root,COG2227@2|Bacteria,1V1MT@1239|Firmicutes,24FTN@186801|Clostridia,3Y29B@572511|Blautia	186801|Clostridia	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,NUDIX
HGCANGJP_00879	1121115.AXVN01000043_gene3376	0.0	1427.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
HGCANGJP_00880	397290.C810_03197	5.09e-78	252.0	COG2333@1|root,COG2333@2|Bacteria,1VCK5@1239|Firmicutes,24ISE@186801|Clostridia,27QBY@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HGCANGJP_00882	397290.C810_03195	4.92e-142	466.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	sidE	GO:0000338,GO:0003674,GO:0003824,GO:0003956,GO:0005575,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009987,GO:0016567,GO:0016579,GO:0016740,GO:0016757,GO:0016763,GO:0016787,GO:0018995,GO:0019538,GO:0019783,GO:0019784,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0061578,GO:0070011,GO:0070536,GO:0070646,GO:0070647,GO:0071704,GO:0101005,GO:0140096,GO:1901564	-	ko:K10110,ko:K15473	ko02010,ko05134,map02010,map05134	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	iLJ478.TM1202	AAA_23,BPD_transp_1,SidE
HGCANGJP_00884	1121115.AXVN01000043_gene3381	6.2e-109	314.0	2E53T@1|root,32ZWT@2|Bacteria,1VJS8@1239|Firmicutes,24S8H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00885	1121115.AXVN01000043_gene3382	6.52e-86	252.0	COG2461@1|root,COG2461@2|Bacteria,1V9ZF@1239|Firmicutes,24F8Y@186801|Clostridia	186801|Clostridia	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00886	1121115.AXVN01000043_gene3383	8.01e-14	70.5	COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,25FVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
HGCANGJP_00887	1121115.AXVN01000043_gene3384	2.16e-267	739.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_00889	742765.HMPREF9457_02207	7.09e-275	764.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,27W7Y@189330|Dorea	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_00890	411459.RUMOBE_00755	6.97e-95	283.0	COG1309@1|root,COG1309@2|Bacteria,1TYNZ@1239|Firmicutes,24IV3@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HGCANGJP_00891	457412.RSAG_00675	0.0	873.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,3WGZS@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
HGCANGJP_00892	457412.RSAG_00674	1.94e-240	661.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia,3WPQY@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
HGCANGJP_00893	1256908.HMPREF0373_00285	7.1e-253	709.0	COG1672@1|root,COG1672@2|Bacteria,1TPQR@1239|Firmicutes,24AIK@186801|Clostridia,25YER@186806|Eubacteriaceae	186801|Clostridia	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PDDEXK_3
HGCANGJP_00894	457412.RSAG_04751	1.86e-254	697.0	COG5279@1|root,COG5279@2|Bacteria,1UT8R@1239|Firmicutes,24CQF@186801|Clostridia,3WRJU@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HGCANGJP_00895	1121115.AXVN01000003_gene1638	1.53e-155	436.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,3Y0FV@572511|Blautia	186801|Clostridia	L	YjbR	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
HGCANGJP_00896	411459.RUMOBE_00520	7.6e-80	241.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,3Y08H@572511|Blautia	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
HGCANGJP_00897	457412.RSAG_00670	0.0	931.0	COG2733@1|root,COG2733@2|Bacteria,1UKI3@1239|Firmicutes,24WBV@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
HGCANGJP_00898	1121115.AXVN01000003_gene1636	0.0	1000.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia,3XZ8V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
HGCANGJP_00899	1121115.AXVN01000003_gene1635	1.14e-175	489.0	COG0500@1|root,COG0500@2|Bacteria,1UKI1@1239|Firmicutes,25FXJ@186801|Clostridia	186801|Clostridia	Q	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
HGCANGJP_00900	457412.RSAG_04750	3.25e-29	104.0	28RQE@1|root,2ZE30@2|Bacteria,1W6E6@1239|Firmicutes,254WA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00901	1121115.AXVN01000003_gene1633	2e-204	565.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3XYHC@572511|Blautia	186801|Clostridia	O	Psort location Extracellular, score	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
HGCANGJP_00902	1121115.AXVN01000003_gene1632	1.81e-293	800.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3XZ3V@572511|Blautia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HGCANGJP_00903	1121115.AXVN01000003_gene1631	0.0	1171.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYWT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
HGCANGJP_00904	1121115.AXVN01000003_gene1630	6.39e-150	422.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3XZKT@572511|Blautia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
HGCANGJP_00905	1121115.AXVN01000003_gene1629	0.0	982.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3XZEG@572511|Blautia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
HGCANGJP_00906	1121115.AXVN01000003_gene1628	1.44e-277	758.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3XYKK@572511|Blautia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
HGCANGJP_00907	457412.RSAG_00644	1.2e-76	228.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3WJE1@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
HGCANGJP_00908	1121115.AXVN01000003_gene1626	8.31e-310	845.0	COG1253@1|root,COG1253@2|Bacteria,1U77R@1239|Firmicutes,25CBE@186801|Clostridia,3XZ2E@572511|Blautia	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HGCANGJP_00909	1121115.AXVN01000003_gene1625	1.38e-167	469.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
HGCANGJP_00910	1121115.AXVN01000003_gene1624	7.9e-166	465.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3XZDI@572511|Blautia	186801|Clostridia	OU	Psort location Cytoplasmic, score 8.87	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HGCANGJP_00911	1121115.AXVN01000003_gene1623	9.66e-219	602.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3XZM3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
HGCANGJP_00912	1121115.AXVN01000003_gene1622	0.0	900.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ00@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
HGCANGJP_00913	457412.RSAG_00638	5.78e-225	622.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
HGCANGJP_00914	457412.RSAG_00637	0.0	1570.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
HGCANGJP_00915	1121115.AXVN01000003_gene1618	9.19e-149	418.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia,3Y2AD@572511|Blautia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HGCANGJP_00916	1121115.AXVN01000094_gene768	1.3e-94	276.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HGCANGJP_00917	457412.RSAG_02035	3.13e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
HGCANGJP_00918	1121115.AXVN01000094_gene766	1.05e-101	294.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3XZVZ@572511|Blautia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
HGCANGJP_00919	1121115.AXVN01000094_gene765	3.85e-180	501.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3XYU9@572511|Blautia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
HGCANGJP_00920	1121115.AXVN01000094_gene764	2.89e-181	505.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3XYPD@572511|Blautia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
HGCANGJP_00921	1121115.AXVN01000094_gene763	1.8e-248	683.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZ7W@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HGCANGJP_00922	1121115.AXVN01000094_gene762	8.15e-204	563.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZE9@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HGCANGJP_00923	457412.RSAG_02041	1.46e-139	394.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3WH1B@541000|Ruminococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
HGCANGJP_00924	457412.RSAG_02042	0.0	1464.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WH4M@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
HGCANGJP_00925	457412.RSAG_02043	9.38e-312	850.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HGCANGJP_00926	1121115.AXVN01000094_gene758	2.01e-133	378.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3XYT9@572511|Blautia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
HGCANGJP_00927	1121115.AXVN01000094_gene757	4.22e-287	786.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
HGCANGJP_00928	457412.RSAG_02046	1.17e-124	355.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WJ0K@541000|Ruminococcaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
HGCANGJP_00929	1121115.AXVN01000094_gene755	0.0	976.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3XZGT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HGCANGJP_00930	457412.RSAG_02051	1.3e-104	302.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,3WJHM@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
HGCANGJP_00931	1121115.AXVN01000189_gene1038	3.39e-183	510.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3XZDC@572511|Blautia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
HGCANGJP_00932	457412.RSAG_02053	9.97e-103	297.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
HGCANGJP_00933	1121115.AXVN01000180_gene2884	1.8e-105	315.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3Y1CE@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_00934	457412.RSAG_02056	3.58e-148	417.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,3WJ59@541000|Ruminococcaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
HGCANGJP_00935	1121115.AXVN01000133_gene744	9.19e-313	853.0	2CGG8@1|root,30FQ1@2|Bacteria,1UEDU@1239|Firmicutes,25JA2@186801|Clostridia,3Y0ZN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00936	1121115.AXVN01000133_gene743	1.39e-294	805.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3Y0A6@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_00937	1121115.AXVN01000133_gene742	6.37e-152	427.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,2487E@186801|Clostridia,3Y0AH@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00939	1121115.AXVN01000133_gene741	2.11e-272	745.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HGCANGJP_00940	1121115.AXVN01000133_gene740	5.38e-131	372.0	COG1595@1|root,COG1595@2|Bacteria,1V9GU@1239|Firmicutes,24KTH@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_00941	457412.RSAG_02064	3.34e-183	511.0	COG5464@1|root,COG5464@2|Bacteria,1V2ZE@1239|Firmicutes,25DF2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
HGCANGJP_00942	1121115.AXVN01000079_gene2733	0.0	932.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,258QF@186801|Clostridia,3Y1Z2@572511|Blautia	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00943	1121115.AXVN01000079_gene2734	1.14e-69	210.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,3Y1TV@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HGCANGJP_00944	1121115.AXVN01000079_gene2735	1.33e-227	625.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,3Y1A4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00945	1121115.AXVN01000079_gene2736	1.57e-37	126.0	2C4UK@1|root,346TK@2|Bacteria,1W0FK@1239|Firmicutes,2530T@186801|Clostridia,3Y21U@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00946	457412.RSAG_02083	1.44e-35	120.0	2E7J1@1|root,33DKE@2|Bacteria,1VM3N@1239|Firmicutes,24VIG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00947	457412.RSAG_02086	8e-131	371.0	COG0400@1|root,COG0400@2|Bacteria,1VBK0@1239|Firmicutes,24N89@186801|Clostridia,3WJI9@541000|Ruminococcaceae	186801|Clostridia	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00948	457412.RSAG_02087	0.0	907.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3WHQP@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
HGCANGJP_00949	457412.RSAG_02088	6.95e-159	444.0	COG1028@1|root,COG1028@2|Bacteria,1V0T9@1239|Firmicutes,24ASP@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HGCANGJP_00950	1121115.AXVN01000079_gene2743	5.17e-123	351.0	COG3275@1|root,COG3275@2|Bacteria,1UZUT@1239|Firmicutes,25BAU@186801|Clostridia,3Y2E5@572511|Blautia	186801|Clostridia	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF_trnsprt
HGCANGJP_00951	1121115.AXVN01000079_gene2744	2.86e-244	670.0	COG1957@1|root,COG1957@2|Bacteria,1TRQQ@1239|Firmicutes,25C8Y@186801|Clostridia,3Y2EI@572511|Blautia	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
HGCANGJP_00952	457412.RSAG_02096	4.77e-225	622.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,3WHSG@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
HGCANGJP_00953	1121115.AXVN01000063_gene713	3.33e-266	729.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
HGCANGJP_00954	1121115.AXVN01000063_gene712	1.83e-259	711.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,25N06@186801|Clostridia,3XYXQ@572511|Blautia	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
HGCANGJP_00955	457412.RSAG_04588	1.84e-263	720.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia,3WGIR@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
HGCANGJP_00956	1121115.AXVN01000063_gene710	2.03e-154	434.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,3XZF3@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
HGCANGJP_00957	1121115.AXVN01000063_gene709	1.01e-181	509.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,3Y07V@572511|Blautia	186801|Clostridia	P	COG COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
HGCANGJP_00958	1121115.AXVN01000063_gene708	2.67e-39	130.0	COG3585@1|root,COG3585@2|Bacteria,1VEPR@1239|Firmicutes,24QTI@186801|Clostridia	186801|Clostridia	H	pfam tobe	mopI	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	TOBE
HGCANGJP_00959	457412.RSAG_02102	1.65e-214	593.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,3WHAS@541000|Ruminococcaceae	186801|Clostridia	P	TIGRFAM DNA binding domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
HGCANGJP_00960	457412.RSAG_02103	8.42e-237	652.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
HGCANGJP_00961	457412.RSAG_02104	0.0	2089.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
HGCANGJP_00962	1121115.AXVN01000063_gene704	7.86e-268	732.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3XYS9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
HGCANGJP_00964	457412.RSAG_02106	3.24e-271	742.0	COG4733@1|root,COG4733@2|Bacteria,1VDWT@1239|Firmicutes,24ZKB@186801|Clostridia,3WMCI@541000|Ruminococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
HGCANGJP_00965	1121115.AXVN01000063_gene702	0.0	892.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1VRK1@1239|Firmicutes,25KN7@186801|Clostridia,3Y1XU@572511|Blautia	186801|Clostridia	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00966	1121115.AXVN01000063_gene701	1.67e-101	298.0	2DR5I@1|root,33A9E@2|Bacteria,1VM5P@1239|Firmicutes,24JQJ@186801|Clostridia,3Y0KF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
HGCANGJP_00967	1121115.AXVN01000063_gene700	0.0	907.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,3XYQ7@572511|Blautia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
HGCANGJP_00976	457412.RSAG_03209	1.62e-192	535.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3WIE9@541000|Ruminococcaceae	186801|Clostridia	D	Stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
HGCANGJP_00977	1121115.AXVN01000115_gene2457	9.42e-202	560.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,3Y09E@572511|Blautia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
HGCANGJP_00978	1121115.AXVN01000115_gene2456	7.18e-234	644.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ29@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HGCANGJP_00979	1121115.AXVN01000115_gene2455	0.0	1217.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3XZ3A@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HGCANGJP_00980	1121115.AXVN01000115_gene2454	0.0	998.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XZ5W@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
HGCANGJP_00981	1121115.AXVN01000115_gene2453	5.28e-53	166.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3Y0F0@572511|Blautia	186801|Clostridia	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
HGCANGJP_00982	457412.RSAG_03203	1.54e-181	511.0	COG5263@1|root,COG5263@2|Bacteria,1UJWN@1239|Firmicutes,25FCE@186801|Clostridia,3WKY6@541000|Ruminococcaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
HGCANGJP_00983	1121115.AXVN01000115_gene2450	3.1e-154	433.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3XYGI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
HGCANGJP_00984	457412.RSAG_03201	5.46e-188	522.0	COG1192@1|root,COG1192@2|Bacteria,1UPGE@1239|Firmicutes,24A5R@186801|Clostridia,3WPYK@541000|Ruminococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,HTH_3
HGCANGJP_00985	1121115.AXVN01000031_gene322	1.24e-31	110.0	2CA4Q@1|root,349NE@2|Bacteria,1VYK2@1239|Firmicutes,253VZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_00986	1121115.AXVN01000031_gene323	2.33e-237	653.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HGCANGJP_00987	1121115.AXVN01000031_gene324	7.83e-284	778.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,3Y07A@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
HGCANGJP_00988	1121115.AXVN01000031_gene325	0.0	919.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia,3XZSU@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
HGCANGJP_00989	1121115.AXVN01000031_gene326	3.54e-195	542.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia,3XZSX@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
HGCANGJP_00990	1121115.AXVN01000031_gene327	2.46e-173	484.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3Y013@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
HGCANGJP_00991	1121115.AXVN01000031_gene330	0.0	1374.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
HGCANGJP_00992	1121115.AXVN01000031_gene331	0.0	2214.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3XZQG@572511|Blautia	186801|Clostridia	KL	Psort location Cytoplasmic, score 8.87	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
HGCANGJP_00993	457412.RSAG_03196	8.3e-123	350.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3WITH@541000|Ruminococcaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
HGCANGJP_00994	1121115.AXVN01000031_gene333	4.54e-291	795.0	COG1408@1|root,COG1408@2|Bacteria,1TS43@1239|Firmicutes,248XA@186801|Clostridia,3XZND@572511|Blautia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HGCANGJP_00995	457412.RSAG_03194	0.0	957.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3WGKF@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
HGCANGJP_00997	1121115.AXVN01000031_gene339	0.0	881.0	COG2942@1|root,COG2942@2|Bacteria,1UQC2@1239|Firmicutes,24D2T@186801|Clostridia,3Y1CF@572511|Blautia	186801|Clostridia	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
HGCANGJP_00998	1121115.AXVN01000031_gene342	3.02e-173	483.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XYV6@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_00999	1121115.AXVN01000031_gene343	0.0	1731.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,3XYZD@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_01000	1121115.AXVN01000031_gene344	1.15e-176	491.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,3XZPR@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
HGCANGJP_01001	1121115.AXVN01000031_gene345	5.75e-206	568.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3XZSF@572511|Blautia	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
HGCANGJP_01002	1121115.AXVN01000031_gene346	2.83e-174	484.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
HGCANGJP_01003	457412.RSAG_03185	7.3e-287	784.0	2EVYD@1|root,33PC0@2|Bacteria,1VUAR@1239|Firmicutes,24ZRA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01004	457412.RSAG_03184	4.54e-201	556.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3WIPT@541000|Ruminococcaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
HGCANGJP_01005	1121115.AXVN01000031_gene349	2.81e-194	539.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,3XZD5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
HGCANGJP_01006	457412.RSAG_03182	0.0	2278.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
HGCANGJP_01007	457412.RSAG_03181	1.65e-240	660.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
HGCANGJP_01008	457412.RSAG_03180	0.0	892.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HGCANGJP_01009	1121115.AXVN01000031_gene353	5.03e-148	417.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3XZZU@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HGCANGJP_01010	1121115.AXVN01000031_gene354	1.82e-179	500.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3XYZF@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
HGCANGJP_01011	1121115.AXVN01000055_gene1900	4.78e-90	265.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3Y0IA@572511|Blautia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
HGCANGJP_01012	1121115.AXVN01000055_gene1901	1.41e-151	434.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
HGCANGJP_01013	1121115.AXVN01000055_gene1902	1.17e-245	674.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3XYMZ@572511|Blautia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
HGCANGJP_01014	1121115.AXVN01000055_gene1903	3.05e-192	533.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3XZNZ@572511|Blautia	186801|Clostridia	H	Biotin-- acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HGCANGJP_01015	1121115.AXVN01000055_gene1904	7.06e-81	239.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,3Y06J@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01016	457412.RSAG_03172	5.96e-240	659.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3WGDN@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
HGCANGJP_01017	1121115.AXVN01000055_gene1906	1.94e-99	290.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3XZTG@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HGCANGJP_01018	457412.RSAG_03271	1.17e-248	682.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,3WJKX@541000|Ruminococcaceae	186801|Clostridia	S	Spore coat protein, CotS family	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
HGCANGJP_01019	457412.RSAG_03270	1.89e-316	862.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
HGCANGJP_01020	1121115.AXVN01000135_gene969	0.0	988.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3XZ9B@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
HGCANGJP_01021	457412.RSAG_03268	3.12e-120	342.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WRVA@541000|Ruminococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
HGCANGJP_01022	1121115.AXVN01000135_gene972	1.38e-102	296.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
HGCANGJP_01023	1121115.AXVN01000135_gene973	4.39e-245	674.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3XZ73@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
HGCANGJP_01024	457412.RSAG_03265	2.77e-260	714.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HGCANGJP_01025	1121115.AXVN01000058_gene2556	0.0	1476.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3XZJV@572511|Blautia	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
HGCANGJP_01026	457412.RSAG_04579	0.0	1315.0	COG5427@1|root,COG5427@2|Bacteria,1UXXM@1239|Firmicutes,24EF9@186801|Clostridia,3WHFN@541000|Ruminococcaceae	186801|Clostridia	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01027	457412.RSAG_03261	1.81e-157	442.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3WIGM@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HGCANGJP_01028	457412.RSAG_03260	0.0	1063.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,3WIAH@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl hydrolase	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
HGCANGJP_01029	1121115.AXVN01000058_gene2552	1.72e-40	133.0	2EHIK@1|root,3498W@2|Bacteria,1VYKX@1239|Firmicutes,252YA@186801|Clostridia,3Y0QM@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01030	457412.RSAG_03258	3.26e-173	483.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
HGCANGJP_01031	1121115.AXVN01000058_gene2550	1.42e-39	131.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,3Y0MQ@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
HGCANGJP_01032	457412.RSAG_03256	1.17e-221	612.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WIJ5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HGCANGJP_01033	457412.RSAG_03255	9e-254	696.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHQZ@541000|Ruminococcaceae	186801|Clostridia	S	transport system permease	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HGCANGJP_01034	457412.RSAG_03254	0.0	979.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
HGCANGJP_01035	457412.RSAG_03253	2.44e-286	781.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,3WSBG@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
HGCANGJP_01036	1121115.AXVN01000058_gene2545	3.78e-20	81.6	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3Y0Q0@572511|Blautia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HGCANGJP_01037	457412.RSAG_03250	5.86e-99	288.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24VXI@186801|Clostridia,3WRY4@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HGCANGJP_01038	1121115.AXVN01000058_gene2543	2.12e-310	847.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3XYP7@572511|Blautia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
HGCANGJP_01039	1121115.AXVN01000058_gene2542	1.21e-94	276.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3XZYF@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
HGCANGJP_01040	1121115.AXVN01000058_gene2541	0.0	1303.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3XYI8@572511|Blautia	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
HGCANGJP_01041	1121115.AXVN01000058_gene2540	3.05e-57	177.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
HGCANGJP_01042	457412.RSAG_03244	3.85e-98	286.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJ32@541000|Ruminococcaceae	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HGCANGJP_01043	1121115.AXVN01000058_gene2538	1.39e-62	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
HGCANGJP_01044	1121115.AXVN01000058_gene2537	1.4e-40	133.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3Y0KE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
HGCANGJP_01045	457412.RSAG_03241	2.71e-177	493.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3WGSY@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
HGCANGJP_01046	1121115.AXVN01000058_gene2535	2.38e-197	546.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3XZ9S@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
HGCANGJP_01047	457412.RSAG_03239	0.0	999.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
HGCANGJP_01048	457412.RSAG_03238	2.87e-311	846.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3WH2V@541000|Ruminococcaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
HGCANGJP_01049	1121115.AXVN01000039_gene3303	7.16e-64	196.0	2F5U3@1|root,33YD0@2|Bacteria,1VVXV@1239|Firmicutes,250VV@186801|Clostridia,3Y21G@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01050	457412.RSAG_03236	0.0	1117.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGRP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_01051	457412.RSAG_03235	1.46e-303	827.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HGCANGJP_01052	1121115.AXVN01000039_gene3300	9.57e-304	832.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	xanP	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
HGCANGJP_01053	457412.RSAG_03233	0.0	1153.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,3WI3C@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HGCANGJP_01054	457412.RSAG_03232	1.3e-194	538.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,3WSCN@541000|Ruminococcaceae	186801|Clostridia	M	Prolipoprotein diacylglyceryl transferase	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HGCANGJP_01055	1121115.AXVN01000039_gene3297	4.93e-208	574.0	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,24K01@186801|Clostridia,3Y08B@572511|Blautia	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
HGCANGJP_01056	457412.RSAG_03230	1.54e-190	530.0	COG3247@1|root,COG3247@2|Bacteria,1VAQW@1239|Firmicutes,24QIF@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
HGCANGJP_01057	457412.RSAG_03229	1.75e-185	516.0	COG2755@1|root,COG2755@2|Bacteria,1VAV9@1239|Firmicutes	1239|Firmicutes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HGCANGJP_01058	457412.RSAG_03228	1.41e-120	344.0	2DNPY@1|root,32YIB@2|Bacteria,1VHHM@1239|Firmicutes,24NJ3@186801|Clostridia,3WMNS@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
HGCANGJP_01059	457412.RSAG_03227	0.0	909.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
HGCANGJP_01060	457412.RSAG_03226	1.21e-284	778.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
HGCANGJP_01061	1121115.AXVN01000039_gene3291	4.31e-172	481.0	COG3279@1|root,COG3279@2|Bacteria,1V3QY@1239|Firmicutes,24IT9@186801|Clostridia,3Y1IK@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_01062	1121115.AXVN01000039_gene3290	8.12e-48	152.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S3M@186801|Clostridia,3Y0WH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01063	1121115.AXVN01000039_gene3289	1.68e-138	390.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,3Y0B0@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
HGCANGJP_01067	556261.HMPREF0240_02035	1.21e-55	174.0	2AJWP@1|root,31AJM@2|Bacteria,1V6IZ@1239|Firmicutes,24NNT@186801|Clostridia,36P76@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01068	1121115.AXVN01000132_gene726	4e-68	206.0	2E6DS@1|root,32JWH@2|Bacteria,1UR8V@1239|Firmicutes,25932@186801|Clostridia,3Y1S7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01069	585394.RHOM_01940	5.16e-72	216.0	2DFD5@1|root,2ZRE1@2|Bacteria,1V4FG@1239|Firmicutes,25CTT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HGCANGJP_01070	665956.HMPREF1032_00028	7.14e-189	525.0	COG4227@1|root,COG4227@2|Bacteria,1TRWD@1239|Firmicutes,248KN@186801|Clostridia,3WGS0@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3846,DUF3848,DUF3849,YodL
HGCANGJP_01071	665956.HMPREF1032_00027	0.0	1315.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,3WGBP@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,MutS_I,N6_Mtase,SNF2_N
HGCANGJP_01072	411471.SUBVAR_04350	0.0	1282.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WGFQ@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,Intron_maturas2,RVT_1
HGCANGJP_01073	665956.HMPREF1032_00027	0.0	4204.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia,3WGBP@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,MutS_I,N6_Mtase,SNF2_N
HGCANGJP_01074	428127.EUBDOL_00095	5.3e-44	142.0	2DP0F@1|root,32TXN@2|Bacteria,1UHKP@1239|Firmicutes	1239|Firmicutes	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
HGCANGJP_01075	657322.FPR_14260	0.0	2167.0	COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,3WI43@541000|Ruminococcaceae	186801|Clostridia	L	YodL-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,Peptidase_M78,YodL,zf-CHC2
HGCANGJP_01076	411470.RUMGNA_00748	2.53e-56	175.0	2AFRJ@1|root,315TI@2|Bacteria,1TUBT@1239|Firmicutes,257XJ@186801|Clostridia,3Y1SN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01077	428127.EUBDOL_00098	0.0	1355.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,3VP6Z@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim
HGCANGJP_01078	428127.EUBDOL_00099	1.82e-155	437.0	28IU3@1|root,2Z8SX@2|Bacteria,1UZB0@1239|Firmicutes,3VSYV@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01079	428127.EUBDOL_00100	2.28e-44	143.0	2CC3W@1|root,3377Z@2|Bacteria,1VJCT@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01080	411461.DORFOR_03211	9.02e-158	445.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,24AUT@186801|Clostridia,27VZI@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
HGCANGJP_01081	411461.DORFOR_03212	2.66e-48	154.0	2AF03@1|root,314Y6@2|Bacteria,1V7JC@1239|Firmicutes,24MUD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
HGCANGJP_01082	585394.RHOM_01875	0.0	1117.0	COG0791@1|root,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
HGCANGJP_01083	585394.RHOM_01870	6.41e-84	248.0	2DZH5@1|root,32VAM@2|Bacteria,1V1MR@1239|Firmicutes,24GI9@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3851
HGCANGJP_01084	585394.RHOM_01865	0.0	1573.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
HGCANGJP_01085	658659.HMPREF0983_01767	9.87e-102	295.0	COG3451@1|root,COG3451@2|Bacteria,1V74G@1239|Firmicutes,3VRCI@526524|Erysipelotrichia	526524|Erysipelotrichia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
HGCANGJP_01086	428127.EUBDOL_01400	2.81e-199	553.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,3VQ0C@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01087	428127.EUBDOL_01399	6.43e-41	135.0	2CDEH@1|root,32RXK@2|Bacteria,1VA17@1239|Firmicutes,3VR9H@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Maff2 family	-	-	-	-	-	-	-	-	-	-	-	-	Maff2
HGCANGJP_01088	742735.HMPREF9467_03093	2.68e-185	523.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,21XRZ@1506553|Lachnoclostridium	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
HGCANGJP_01089	411473.RUMCAL_01420	1.81e-27	99.8	2E8ED@1|root,332SU@2|Bacteria,1VJ6A@1239|Firmicutes,24SJK@186801|Clostridia,3WKU3@541000|Ruminococcaceae	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
HGCANGJP_01090	1232443.BAIA02000032_gene1953	0.0	1231.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia,26CSZ@186813|unclassified Clostridiales	186801|Clostridia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
HGCANGJP_01091	411462.DORLON_00197	0.0	968.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,27WFG@189330|Dorea	186801|Clostridia	D	COG COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HGCANGJP_01092	411462.DORLON_00196	3.51e-73	221.0	292P2@1|root,2ZQ6W@2|Bacteria,1V4YF@1239|Firmicutes,24I6C@186801|Clostridia,27WS7@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
HGCANGJP_01093	1226322.HMPREF1545_00002	1.2e-134	382.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,24I94@186801|Clostridia,2N8G1@216572|Oscillospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_01094	411462.DORLON_00194	0.0	1234.0	COG4652@1|root,COG4652@2|Bacteria,1U507@1239|Firmicutes,249H3@186801|Clostridia,27WFW@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1430
HGCANGJP_01095	411459.RUMOBE_00651	1.07e-74	223.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,3Y0N9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_01096	411459.RUMOBE_00652	0.0	1723.0	COG1961@1|root,COG3505@1|root,COG1961@2|Bacteria,COG3505@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
HGCANGJP_01097	556261.HMPREF0240_03660	3.08e-108	312.0	28I1B@1|root,2Z860@2|Bacteria,1TT6W@1239|Firmicutes,24BUI@186801|Clostridia,36GSP@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
HGCANGJP_01098	556261.HMPREF0240_03659	1.83e-96	280.0	28NFE@1|root,324KA@2|Bacteria,1UQUR@1239|Firmicutes,257SV@186801|Clostridia,36TJW@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4313
HGCANGJP_01099	556261.HMPREF0240_03658	3.43e-71	214.0	2B1PF@1|root,2ZYHN@2|Bacteria,1V614@1239|Firmicutes,24HJ9@186801|Clostridia,36VTN@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01100	411470.RUMGNA_00784	1.29e-179	499.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia,3Y0G5@572511|Blautia	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ANT,Bro-N
HGCANGJP_01101	552398.HMPREF0866_02410	4.28e-178	499.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia,3WKE9@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36,RepA_N
HGCANGJP_01102	552398.HMPREF0866_02409	4.7e-39	129.0	2E5WX@1|root,330KV@2|Bacteria,1VFRK@1239|Firmicutes,24N91@186801|Clostridia,3WQ4U@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01103	658659.HMPREF0983_01777	1.04e-59	184.0	2B1PF@1|root,31U4Y@2|Bacteria,1V8C1@1239|Firmicutes,3VTMM@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01104	428127.EUBDOL_01390	1.62e-203	565.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,3VQ3M@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HGCANGJP_01105	585394.RHOM_01480	6.33e-188	523.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HGCANGJP_01106	1121115.AXVN01000132_gene728	0.0	899.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ78@572511|Blautia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
HGCANGJP_01107	1121115.AXVN01000132_gene729	7.81e-29	104.0	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24NT8@186801|Clostridia,3Y0CG@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01108	1121115.AXVN01000132_gene730	1.45e-161	452.0	COG0546@1|root,COG0546@2|Bacteria,1UHUD@1239|Firmicutes,25E2T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HGCANGJP_01109	457412.RSAG_02429	0.0	1433.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
HGCANGJP_01110	457412.RSAG_04538	3.37e-88	270.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
HGCANGJP_01111	1121115.AXVN01000002_gene1390	3.21e-178	496.0	COG0463@1|root,COG0463@2|Bacteria,1TRRK@1239|Firmicutes,24CHM@186801|Clostridia,3Y03K@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HGCANGJP_01112	1121115.AXVN01000002_gene1391	2.51e-56	175.0	2F99N@1|root,340RC@2|Bacteria,1VX34@1239|Firmicutes,257JQ@186801|Clostridia,3Y26Y@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01113	457412.RSAG_00028	0.0	1019.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1V1JE@1239|Firmicutes,24GTB@186801|Clostridia,3WK9S@541000|Ruminococcaceae	186801|Clostridia	D	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01114	1121115.AXVN01000002_gene1393	0.0	1203.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HGCANGJP_01115	1121115.AXVN01000002_gene1394	1.09e-270	739.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,3XZ06@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
HGCANGJP_01116	457412.RSAG_00031	2.57e-28	110.0	COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,247TS@186801|Clostridia	186801|Clostridia	Q	PFAM Collagen triple helix	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
HGCANGJP_01117	1121115.AXVN01000002_gene1396	0.0	1066.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_01118	457412.RSAG_00033	4.17e-194	538.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,3WHDE@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
HGCANGJP_01119	1121115.AXVN01000002_gene1398	9.38e-317	863.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3Y170@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
HGCANGJP_01120	1121115.AXVN01000002_gene1399	2.86e-217	600.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
HGCANGJP_01121	457412.RSAG_00036	5.29e-196	542.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,3WHKS@541000|Ruminococcaceae	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
HGCANGJP_01122	1121115.AXVN01000002_gene1401	1.56e-90	265.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
HGCANGJP_01123	457412.RSAG_00038	0.0	1286.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3WGR6@541000|Ruminococcaceae	186801|Clostridia	C	NAD(P)-binding Rossmann-like domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
HGCANGJP_01124	1121115.AXVN01000002_gene1403	5.15e-109	313.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,3Y10T@572511|Blautia	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
HGCANGJP_01125	1121115.AXVN01000002_gene1404	9.19e-243	665.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,3Y13N@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
HGCANGJP_01126	1121115.AXVN01000002_gene1405	3.17e-264	721.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3Y1ET@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
HGCANGJP_01127	1121115.AXVN01000002_gene1406	1.87e-215	593.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3Y1HE@572511|Blautia	186801|Clostridia	CH	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
HGCANGJP_01128	1121115.AXVN01000002_gene1407	2.32e-166	464.0	COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7,Fer4_9
HGCANGJP_01129	457412.RSAG_00043	0.0	1063.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
HGCANGJP_01130	1121115.AXVN01000002_gene1409	1.41e-208	575.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3XZ8S@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
HGCANGJP_01131	1121115.AXVN01000002_gene1410	7.64e-131	371.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3XZI9@572511|Blautia	186801|Clostridia	C	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
HGCANGJP_01132	457412.RSAG_00046	1.76e-165	462.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3WIT8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
HGCANGJP_01133	1121115.AXVN01000002_gene1412	4.82e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HGCANGJP_01134	1121115.AXVN01000002_gene1413	0.0	1226.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3XZ6P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HGCANGJP_01135	457412.RSAG_00049	0.0	1142.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3WGMQ@541000|Ruminococcaceae	186801|Clostridia	C	hydrogenase large subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
HGCANGJP_01136	457412.RSAG_00050	0.0	901.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,3WSIQ@541000|Ruminococcaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
HGCANGJP_01137	457412.RSAG_00051	2.54e-84	248.0	COG5341@1|root,COG5341@2|Bacteria,1UQFQ@1239|Firmicutes,25873@186801|Clostridia,3WM3Y@541000|Ruminococcaceae	186801|Clostridia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
HGCANGJP_01138	1121115.AXVN01000002_gene1417	0.0	1008.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3XZ0V@572511|Blautia	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HGCANGJP_01139	1121115.AXVN01000002_gene1418	3.5e-218	600.0	COG0152@1|root,COG0152@2|Bacteria,1UF8J@1239|Firmicutes,25K96@186801|Clostridia,3XZ70@572511|Blautia	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
HGCANGJP_01140	457412.RSAG_00054	5.96e-240	659.0	2DUPT@1|root,33RMR@2|Bacteria,1UKHV@1239|Firmicutes,25FXD@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HGCANGJP_01141	1121115.AXVN01000002_gene1420	1.53e-36	125.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,3Y0MU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01142	457412.RSAG_00056	4.75e-214	595.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,3WGPF@541000|Ruminococcaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
HGCANGJP_01143	1121115.AXVN01000002_gene1422	0.0	922.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
HGCANGJP_01144	1121115.AXVN01000002_gene1423	7.39e-247	682.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,3XZ1Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
HGCANGJP_01145	1121115.AXVN01000002_gene1424	4.54e-63	192.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,3Y0F2@572511|Blautia	186801|Clostridia	S	COG NOG21970 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
HGCANGJP_01146	457412.RSAG_00060	7.14e-39	129.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3WKEV@541000|Ruminococcaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HGCANGJP_01147	457412.RSAG_00061	1.14e-42	140.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,3WKEJ@541000|Ruminococcaceae	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
HGCANGJP_01148	457412.RSAG_00063	0.0	1414.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
HGCANGJP_01149	1410632.JHWW01000021_gene418	3.44e-11	58.5	2DRWB@1|root,33DDT@2|Bacteria,1VKGH@1239|Firmicutes,24VWG@186801|Clostridia,27PQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
HGCANGJP_01150	457412.RSAG_00065	6.61e-110	316.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,3WM1R@541000|Ruminococcaceae	186801|Clostridia	L	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HGCANGJP_01151	1121115.AXVN01000002_gene1429	1.46e-48	157.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3Y0EI@572511|Blautia	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01152	1121115.AXVN01000002_gene1430	0.0	1317.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3XYS4@572511|Blautia	186801|Clostridia	P	COG COG2217 Cation transport ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
HGCANGJP_01153	457412.RSAG_00488	2.24e-93	278.0	2FCDN@1|root,344H7@2|Bacteria,1W31R@1239|Firmicutes,256SW@186801|Clostridia	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01154	1121115.AXVN01000026_gene999	5.76e-37	130.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
HGCANGJP_01157	1121115.AXVN01000026_gene997	3.56e-193	539.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3XZ81@572511|Blautia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
HGCANGJP_01158	457412.RSAG_00494	7.11e-172	480.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
HGCANGJP_01159	1121115.AXVN01000026_gene995	1.67e-174	487.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3XZSS@572511|Blautia	186801|Clostridia	J	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HGCANGJP_01160	457412.RSAG_00496	0.0	1316.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
HGCANGJP_01161	1121115.AXVN01000026_gene993	1.94e-216	597.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,3XYHB@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_01162	1121115.AXVN01000026_gene992	2.53e-80	238.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,3Y09K@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HGCANGJP_01163	1121115.AXVN01000026_gene991	9.19e-168	470.0	COG1266@1|root,COG1266@2|Bacteria,1W749@1239|Firmicutes,25MB2@186801|Clostridia,3Y0CJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HGCANGJP_01164	457412.RSAG_00500	1.29e-149	421.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HGCANGJP_01165	457412.RSAG_00501	3.13e-120	357.0	2CAM6@1|root,33TP6@2|Bacteria,1VTBW@1239|Firmicutes,24Z6R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01166	457412.RSAG_00502	1.52e-300	820.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
HGCANGJP_01167	1121115.AXVN01000026_gene987	0.0	1161.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3XZ10@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
HGCANGJP_01168	457412.RSAG_00504	7.78e-202	559.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,3WGV0@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HGCANGJP_01169	1121115.AXVN01000026_gene985	0.0	1016.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HGCANGJP_01170	1121115.AXVN01000026_gene984	2.97e-54	169.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HGCANGJP_01171	1121115.AXVN01000026_gene983	1.88e-290	794.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ33@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HGCANGJP_01172	457412.RSAG_00508	0.0	1285.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,3WI0T@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
HGCANGJP_01173	457412.RSAG_00509	7.73e-155	435.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_01174	457412.RSAG_00510	9.91e-307	842.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,3WI4Z@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HGCANGJP_01175	457412.RSAG_00511	3.13e-274	752.0	COG2247@1|root,COG2247@2|Bacteria,1TUN7@1239|Firmicutes,24Y24@186801|Clostridia,3WMU5@541000|Ruminococcaceae	186801|Clostridia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01176	1121115.AXVN01000029_gene634	4.97e-170	476.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,3XZD6@572511|Blautia	186801|Clostridia	S	Sulfite exporter TauE/SafE	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
HGCANGJP_01177	1121115.AXVN01000029_gene635	0.0	1172.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3XZ1M@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
HGCANGJP_01178	1121115.AXVN01000029_gene636	4.11e-293	800.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3XYX1@572511|Blautia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
HGCANGJP_01179	457412.RSAG_00515	8.1e-160	447.0	COG2206@1|root,COG2206@2|Bacteria,1V54U@1239|Firmicutes,24HUA@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
HGCANGJP_01180	457412.RSAG_00516	0.0	1003.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HGCANGJP_01181	1121115.AXVN01000029_gene639	1.59e-156	438.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3Y04N@572511|Blautia	186801|Clostridia	S	COG COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HGCANGJP_01182	1121115.AXVN01000029_gene640	0.0	1503.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3XZ3M@572511|Blautia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
HGCANGJP_01183	1121115.AXVN01000029_gene641	4.17e-119	340.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3XZ59@572511|Blautia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
HGCANGJP_01184	1121115.AXVN01000029_gene642	0.0	1115.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3XZHQ@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HGCANGJP_01185	1121115.AXVN01000029_gene643	0.0	1439.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3XYSY@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
HGCANGJP_01186	1121115.AXVN01000029_gene644	0.0	943.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3XZ42@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
HGCANGJP_01187	1121115.AXVN01000029_gene645	1.83e-20	81.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3Y0JJ@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
HGCANGJP_01188	1121115.AXVN01000029_gene646	8.43e-73	219.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,3Y0RE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
HGCANGJP_01189	1121115.AXVN01000029_gene647	3.98e-253	706.0	2ENTE@1|root,33GEK@2|Bacteria,1VSB4@1239|Firmicutes,24YR1@186801|Clostridia,3XZII@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01190	1121115.AXVN01000029_gene648	2.26e-286	785.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3XZS0@572511|Blautia	186801|Clostridia	S	COG COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
HGCANGJP_01191	457412.RSAG_00527	2.54e-144	406.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia,3WITP@541000|Ruminococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HGCANGJP_01192	1121115.AXVN01000029_gene650	4.72e-150	425.0	COG0860@1|root,COG0860@2|Bacteria,1TS91@1239|Firmicutes,25B1N@186801|Clostridia,3XZHM@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SPOR
HGCANGJP_01193	411459.RUMOBE_02892	0.0	1055.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYKU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_01194	1121115.AXVN01000008_gene2688	0.0	1127.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HGCANGJP_01195	457412.RSAG_02568	9.88e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3WJE7@541000|Ruminococcaceae	186801|Clostridia	E	Small subunit of acetolactate synthase	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
HGCANGJP_01196	457412.RSAG_02569	1.65e-304	830.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WGV5@541000|Ruminococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HGCANGJP_01197	457412.RSAG_02570	7.44e-169	471.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3WIW2@541000|Ruminococcaceae	186801|Clostridia	E	PHP domain protein	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
HGCANGJP_01198	1121115.AXVN01000008_gene2689	2e-74	225.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3XZ1J@572511|Blautia	186801|Clostridia	E	COG COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
HGCANGJP_01199	1121115.AXVN01000008_gene2712	8.49e-128	365.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3XZCZ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
HGCANGJP_01200	1121115.AXVN01000008_gene2713	3.01e-226	624.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia,3XZ5P@572511|Blautia	186801|Clostridia	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
HGCANGJP_01201	1121115.AXVN01000008_gene2690	9.43e-24	99.8	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3XYYM@572511|Blautia	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HGCANGJP_01202	1121115.AXVN01000008_gene2715	1.55e-274	752.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3XYNH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HGCANGJP_01203	457412.RSAG_02578	3.54e-180	501.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
HGCANGJP_01204	1121115.AXVN01000008_gene2717	1.05e-36	124.0	2FAZC@1|root,34364@2|Bacteria,1VXA9@1239|Firmicutes,252GU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01205	457412.RSAG_02580	6.84e-156	438.0	COG2364@1|root,COG2364@2|Bacteria,1US08@1239|Firmicutes,24DPK@186801|Clostridia,3WIPK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01206	1121115.AXVN01000008_gene2719	0.0	925.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3XZ4X@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
HGCANGJP_01207	1121115.AXVN01000008_gene2720	8.09e-127	360.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3Y0MC@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
HGCANGJP_01208	457412.RSAG_02584	0.0	1073.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
HGCANGJP_01210	1121115.AXVN01000157_gene539	0.0	1168.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
HGCANGJP_01211	33035.JPJF01000009_gene1487	1.42e-19	89.4	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_01212	457412.RSAG_02589	4.64e-178	501.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3WGP1@541000|Ruminococcaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_01213	411490.ANACAC_02243	2.64e-49	157.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NM2@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
HGCANGJP_01214	411489.CLOL250_00469	4.44e-134	387.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,36DVE@31979|Clostridiaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
HGCANGJP_01215	537007.BLAHAN_04047	2.47e-62	199.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,3Y0KB@572511|Blautia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
HGCANGJP_01216	411490.ANACAC_02245	1.9e-92	272.0	COG1468@1|root,COG1468@2|Bacteria,1V781@1239|Firmicutes,24IBG@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
HGCANGJP_01217	411469.EUBHAL_00994	2.18e-288	820.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,25W5E@186806|Eubacteriaceae	186801|Clostridia	L	DEAD-like helicases superfamily	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
HGCANGJP_01218	537007.BLAHAN_04050	7.83e-128	368.0	COG1688@1|root,COG1688@2|Bacteria,1UYJD@1239|Firmicutes,24BJA@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein Cas5	cas5	-	-	ko:K19090	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
HGCANGJP_01219	537007.BLAHAN_04051	5.99e-163	461.0	COG1857@1|root,COG1857@2|Bacteria,1TRGS@1239|Firmicutes,24CU1@186801|Clostridia	186801|Clostridia	L	CRISPR-associated regulatory protein, DevR family	cst2	-	-	ko:K19075	-	-	-	-	ko00000,ko02048	-	-	-	DevR
HGCANGJP_01220	537007.BLAHAN_04052	4.8e-227	645.0	28HTI@1|root,2Z80D@2|Bacteria,1TPRZ@1239|Firmicutes,24BPP@186801|Clostridia	186801|Clostridia	S	CRISPR-associated cxxc_cxxc protein Cst1	cst1	-	-	ko:K19088	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CXXC_CXXC
HGCANGJP_01221	483218.BACPEC_01855	6.44e-88	267.0	COG1583@1|root,COG1583@2|Bacteria,1VC7U@1239|Firmicutes,24CJS@186801|Clostridia	186801|Clostridia	L	CRISPR-associated endoribonuclease Cas6	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
HGCANGJP_01222	457412.RSAG_02597	0.0	1213.0	COG0426@1|root,COG1773@1|root,COG1853@1|root,COG0426@2|Bacteria,COG1773@2|Bacteria,COG1853@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
HGCANGJP_01223	457412.RSAG_02598	2.52e-282	771.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HGCANGJP_01224	457412.RSAG_02599	0.0	1250.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
HGCANGJP_01225	457412.RSAG_02600	2.62e-207	573.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3WIV4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
HGCANGJP_01226	457412.RSAG_04618	0.0	1898.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,SBP_bac_3
HGCANGJP_01227	1121115.AXVN01000089_gene2816	0.0	1228.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,3Y15J@572511|Blautia	186801|Clostridia	FG	ABC transporter substrate-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_01228	1121115.AXVN01000089_gene2815	0.0	1374.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3Y1FS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HGCANGJP_01229	1121115.AXVN01000089_gene2814	8.74e-194	537.0	COG0834@1|root,COG0834@2|Bacteria,1UYKY@1239|Firmicutes,24C0B@186801|Clostridia,3Y14K@572511|Blautia	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HGCANGJP_01230	1121115.AXVN01000089_gene2813	3.24e-308	842.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYX6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01231	1121115.AXVN01000089_gene2812	1.64e-103	299.0	COG1522@1|root,COG1522@2|Bacteria,1V1DR@1239|Firmicutes,25DYB@186801|Clostridia,3Y283@572511|Blautia	186801|Clostridia	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
HGCANGJP_01232	457412.RSAG_04623	1.05e-115	342.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WHF6@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01233	411461.DORFOR_02091	6.49e-81	246.0	COG1396@1|root,COG1396@2|Bacteria,1UYE6@1239|Firmicutes,24CI9@186801|Clostridia,27WW1@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HGCANGJP_01234	411459.RUMOBE_03514	1.94e-66	202.0	COG1695@1|root,COG1695@2|Bacteria,1TTYT@1239|Firmicutes,25ND6@186801|Clostridia,3Y0W1@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HGCANGJP_01235	411459.RUMOBE_03513	9.09e-100	292.0	2BFW1@1|root,329RG@2|Bacteria,1V9MM@1239|Firmicutes,24JYR@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
HGCANGJP_01236	411467.BACCAP_02985	6.26e-66	216.0	28MEH@1|root,2ZAS4@2|Bacteria,1UYV3@1239|Firmicutes,25HJD@186801|Clostridia,269QX@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01238	1121115.AXVN01000116_gene2324	0.0	1046.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3XZJV@572511|Blautia	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
HGCANGJP_01239	1235800.C819_02851	4.85e-82	263.0	2E4RQ@1|root,32ZK7@2|Bacteria,1VI66@1239|Firmicutes,24TZR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01240	511680.BUTYVIB_02250	2.11e-78	240.0	COG1595@1|root,COG1595@2|Bacteria,1UZ1M@1239|Firmicutes,24AUS@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_01242	1121115.AXVN01000034_gene3891	2.02e-270	739.0	2BF19@1|root,328T3@2|Bacteria,1VAXF@1239|Firmicutes,258NW@186801|Clostridia,3Y0UJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01243	1121115.AXVN01000034_gene3890	2.27e-271	753.0	COG0845@1|root,COG0845@2|Bacteria,1V156@1239|Firmicutes,24E26@186801|Clostridia,3Y06F@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
HGCANGJP_01244	1121115.AXVN01000034_gene3889	1.56e-199	554.0	COG0395@1|root,COG0395@2|Bacteria,1TS82@1239|Firmicutes,2488S@186801|Clostridia,3XYW1@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_01245	1121115.AXVN01000034_gene3888	2.28e-222	613.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,3Y0K9@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_01246	1121115.AXVN01000034_gene3887	0.0	1519.0	COG1653@1|root,COG1653@2|Bacteria,1V04I@1239|Firmicutes,247SU@186801|Clostridia,3XZJE@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_01247	1121115.AXVN01000034_gene3886	1.98e-157	441.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia,3XYX9@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_01248	1121115.AXVN01000034_gene3885	5.94e-295	806.0	COG5002@1|root,COG5002@2|Bacteria,1URKI@1239|Firmicutes,248WK@186801|Clostridia,3XZE3@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_01249	1121115.AXVN01000034_gene3884	4.88e-49	155.0	2EMT3@1|root,33FFH@2|Bacteria,1VMD0@1239|Firmicutes,24V8U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01250	1121115.AXVN01000034_gene3883	1.43e-135	383.0	2DKVF@1|root,30GMW@2|Bacteria,1V8RI@1239|Firmicutes,250I2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
HGCANGJP_01251	1121115.AXVN01000034_gene3882	3.49e-48	153.0	2EIQY@1|root,33CGC@2|Bacteria,1VN28@1239|Firmicutes,24WWB@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
HGCANGJP_01252	742765.HMPREF9457_02920	8.38e-42	137.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,HTH_26,HTH_3
HGCANGJP_01253	1121115.AXVN01000034_gene3880	7.63e-72	215.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia,3Y20H@572511|Blautia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
HGCANGJP_01254	1121115.AXVN01000034_gene3879	6.2e-122	349.0	COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia,3Y0DC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	Cytidylate_kin2
HGCANGJP_01255	1121115.AXVN01000034_gene3878	2.09e-93	273.0	COG1846@1|root,COG1846@2|Bacteria,1V9N7@1239|Firmicutes,24NET@186801|Clostridia,3Y0N0@572511|Blautia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HGCANGJP_01256	1121115.AXVN01000034_gene3876	1.91e-261	723.0	COG2199@1|root,COG4684@1|root,COG2199@2|Bacteria,COG4684@2|Bacteria	2|Bacteria	S	ECF transporter, substrate-specific component	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	EAL,ECF_trnsprt,GGDEF,HATPase_c,HisKA,PAS_3
HGCANGJP_01257	1121115.AXVN01000034_gene3874	0.0	1081.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,3XZSV@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_01258	1121115.AXVN01000034_gene3873	0.0	1111.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,3XZ4W@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_01259	1121115.AXVN01000034_gene3872	1.2e-151	426.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,3XZTU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HGCANGJP_01260	1121115.AXVN01000034_gene3871	1.96e-170	476.0	COG2138@1|root,COG2138@2|Bacteria,1V7F7@1239|Firmicutes,24JKU@186801|Clostridia	186801|Clostridia	S	Cobalamin (vitamin B12) biosynthesis CbiX protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01261	1121115.AXVN01000034_gene3870	5.42e-254	696.0	COG4977@1|root,COG4977@2|Bacteria,1UK39@1239|Firmicutes,25FHZ@186801|Clostridia,3Y1JI@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HGCANGJP_01262	1256908.HMPREF0373_01304	2.8e-185	515.0	COG1073@1|root,COG1073@2|Bacteria,1TQ63@1239|Firmicutes,24A0A@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01263	1121115.AXVN01000034_gene3868	1.7e-239	656.0	COG1073@1|root,COG1073@2|Bacteria,1TTB0@1239|Firmicutes,24ATA@186801|Clostridia,3Y186@572511|Blautia	186801|Clostridia	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	BAAT_C
HGCANGJP_01264	1121115.AXVN01000034_gene3867	1.75e-186	518.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,3Y152@572511|Blautia	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
HGCANGJP_01265	411461.DORFOR_02199	4.27e-177	494.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01266	1121115.AXVN01000034_gene3865	4.53e-158	442.0	COG0500@1|root,COG2226@2|Bacteria,1UVT3@1239|Firmicutes,25B9E@186801|Clostridia,3Y2DZ@572511|Blautia	186801|Clostridia	Q	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
HGCANGJP_01267	1280698.AUJS01000017_gene1816	1.08e-160	461.0	COG1397@1|root,COG1397@2|Bacteria,1TQPF@1239|Firmicutes,24AQ2@186801|Clostridia	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,SseB
HGCANGJP_01268	796945.HMPREF1145_0817	8.3e-198	562.0	COG4268@1|root,COG4268@2|Bacteria,1TQEF@1239|Firmicutes,24DVI@186801|Clostridia,2PT42@265975|Oribacterium	186801|Clostridia	V	McrBC 5-methylcytosine restriction system component	-	-	-	-	-	-	-	-	-	-	-	-	McrBC
HGCANGJP_01269	796945.HMPREF1145_0816	0.0	944.0	COG0507@1|root,COG1401@1|root,COG0507@2|Bacteria,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia,2PST6@265975|Oribacterium	186801|Clostridia	V	AAA domain (dynein-related subfamily)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
HGCANGJP_01270	457412.RSAG_02495	0.0	1085.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_5,Glycos_transf_1
HGCANGJP_01271	1121115.AXVN01000034_gene3863	1.04e-136	387.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_01272	1121115.AXVN01000034_gene3862	3.54e-311	850.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYNC@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01273	457412.RSAG_02498	8.14e-120	342.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia,3WSF7@541000|Ruminococcaceae	186801|Clostridia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
HGCANGJP_01274	1121115.AXVN01000034_gene3860	5.41e-47	150.0	2CD8N@1|root,3400U@2|Bacteria,1VWX5@1239|Firmicutes,252JF@186801|Clostridia,3Y1RB@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01275	457412.RSAG_02504	0.0	1631.0	COG2909@1|root,COG2909@2|Bacteria,1TT0M@1239|Firmicutes,24BMZ@186801|Clostridia,3WHDT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
HGCANGJP_01276	1121115.AXVN01000060_gene468	3.35e-39	132.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HGCANGJP_01277	457412.RSAG_00850	4.8e-308	842.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01278	457412.RSAG_00851	4.42e-249	684.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3WRV6@541000|Ruminococcaceae	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
HGCANGJP_01279	457412.RSAG_00852	0.0	1329.0	COG0642@1|root,COG3452@1|root,COG0642@2|Bacteria,COG3452@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,dCache_1
HGCANGJP_01280	457412.RSAG_00853	0.0	1720.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WN7G@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
HGCANGJP_01281	457412.RSAG_00854	9.41e-164	458.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HGCANGJP_01282	457412.RSAG_00855	4.86e-175	487.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3WGU7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
HGCANGJP_01283	457412.RSAG_00856	0.0	1056.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3WGG6@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
HGCANGJP_01284	457412.RSAG_00857	8.62e-222	610.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V0PV@1239|Firmicutes,24BUX@186801|Clostridia,3WRIE@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
HGCANGJP_01285	457412.RSAG_00858	5.01e-294	802.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3WHA7@541000|Ruminococcaceae	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HGCANGJP_01286	457412.RSAG_00859	1.26e-88	259.0	2DH0B@1|root,2ZXXZ@2|Bacteria,1W4MJ@1239|Firmicutes,257EH@186801|Clostridia	457412.RSAG_00859|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01287	457412.RSAG_02983	1.17e-149	420.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,3WHN9@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
HGCANGJP_01288	457412.RSAG_02982	2.41e-111	319.0	2AJD7@1|root,319YQ@2|Bacteria,1V83F@1239|Firmicutes,24FWU@186801|Clostridia,3WP2T@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01289	1158610.UC3_00416	8.38e-05	50.4	2DFJB@1|root,2ZS2G@2|Bacteria,1W6B0@1239|Firmicutes,4IA6K@91061|Bacilli,4B55W@81852|Enterococcaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HGCANGJP_01290	742765.HMPREF9457_00650	2.38e-50	159.0	2AD7W@1|root,312WU@2|Bacteria,1V7M4@1239|Firmicutes,24M52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01291	397288.C806_04703	1.52e-177	510.0	COG0534@1|root,COG0534@2|Bacteria,1TQWU@1239|Firmicutes,24BZG@186801|Clostridia,27JMH@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01292	457415.HMPREF1006_01658	1.9e-36	129.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HGCANGJP_01293	411470.RUMGNA_00823	2.57e-135	387.0	2DBGG@1|root,2Z94H@2|Bacteria,1V0JX@1239|Firmicutes,24CAV@186801|Clostridia,3Y11T@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01294	411459.RUMOBE_03477	0.0	944.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,25EHI@186801|Clostridia,3XZKG@572511|Blautia	186801|Clostridia	S	COG COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HGCANGJP_01295	411459.RUMOBE_03478	8.39e-59	182.0	28NQR@1|root,2ZBQ4@2|Bacteria,1V3BU@1239|Firmicutes,24FVP@186801|Clostridia,3Y035@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01296	411459.RUMOBE_03479	9.51e-47	150.0	2DAN3@1|root,32TVS@2|Bacteria,1VABD@1239|Firmicutes,2598P@186801|Clostridia,3Y0GU@572511|Blautia	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
HGCANGJP_01297	500632.CLONEX_02356	6.82e-133	378.0	COG1396@1|root,COG1396@2|Bacteria,1TRKK@1239|Firmicutes,24C0F@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01298	411459.RUMOBE_03481	8.82e-302	824.0	COG0582@1|root,COG0582@2|Bacteria,1TSQW@1239|Firmicutes,249T6@186801|Clostridia,3XZQW@572511|Blautia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HGCANGJP_01299	457412.RSAG_02969	5.76e-216	597.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HGCANGJP_01300	457412.RSAG_02967	2.74e-96	280.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
HGCANGJP_01301	457412.RSAG_02966	0.0	876.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WNWQ@541000|Ruminococcaceae	186801|Clostridia	V	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01302	457412.RSAG_02964	9.45e-152	426.0	COG0454@1|root,COG0456@2|Bacteria,1V7I8@1239|Firmicutes,24G1V@186801|Clostridia,3WMG1@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_01303	457412.RSAG_02963	1.37e-87	256.0	2DH0B@1|root,2ZXXZ@2|Bacteria,1W4MJ@1239|Firmicutes,257EH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01304	457412.RSAG_02962	6.48e-306	833.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,249UX@186801|Clostridia,3WGND@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
HGCANGJP_01305	1121115.AXVN01000035_gene3820	0.0	875.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,258AG@186801|Clostridia,3Y0AF@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
HGCANGJP_01306	457412.RSAG_02958	1.93e-64	196.0	COG0655@1|root,33Y36@2|Bacteria,1VWHE@1239|Firmicutes,25123@186801|Clostridia	186801|Clostridia	S	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01307	457412.RSAG_02956	8.15e-167	468.0	COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,24AY1@186801|Clostridia,3WJ6R@541000|Ruminococcaceae	186801|Clostridia	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
HGCANGJP_01308	457412.RSAG_02955	6.6e-255	700.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3WIF6@541000|Ruminococcaceae	186801|Clostridia	S	PFAM YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
HGCANGJP_01309	457412.RSAG_02954	4.75e-246	674.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3WGRE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
HGCANGJP_01310	457412.RSAG_02953	8.38e-152	427.0	COG1418@1|root,COG1418@2|Bacteria,1UI0F@1239|Firmicutes,24GIY@186801|Clostridia,3WSS1@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
HGCANGJP_01311	457412.RSAG_02951	2.06e-143	405.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3WG7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HGCANGJP_01312	1121115.AXVN01000035_gene3829	4.02e-304	828.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3XYM5@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
HGCANGJP_01313	457412.RSAG_02949	2.06e-150	423.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,3WI82@541000|Ruminococcaceae	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
HGCANGJP_01314	1121115.AXVN01000035_gene3831	1.86e-89	262.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia,3Y0GT@572511|Blautia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
HGCANGJP_01315	1121115.AXVN01000035_gene3832	6.22e-74	221.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia,3Y0MG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
HGCANGJP_01316	457412.RSAG_02946	0.0	1228.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
HGCANGJP_01317	1121115.AXVN01000035_gene3834	4.26e-45	146.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,3Y0M4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HGCANGJP_01318	457412.RSAG_02944	9.05e-93	271.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
HGCANGJP_01319	1121115.AXVN01000035_gene3836	2.28e-58	180.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3Y0G3@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
HGCANGJP_01320	1121115.AXVN01000008_gene2684	5.19e-273	748.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y04D@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HGCANGJP_01321	1121115.AXVN01000008_gene2683	1.84e-155	436.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
HGCANGJP_01322	1121115.AXVN01000008_gene2682	6.09e-254	697.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
HGCANGJP_01323	457412.RSAG_02553	2.61e-147	415.0	COG2364@1|root,COG2364@2|Bacteria,1V1ZQ@1239|Firmicutes,24GEW@186801|Clostridia,3WRWZ@541000|Ruminococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
HGCANGJP_01324	1121115.AXVN01000008_gene2680	2.31e-198	550.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,3XYU6@572511|Blautia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
HGCANGJP_01325	1121115.AXVN01000008_gene2679	5.47e-159	445.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3XZ6R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
HGCANGJP_01326	1121115.AXVN01000008_gene2678	7.75e-299	819.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3XZ1B@572511|Blautia	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
HGCANGJP_01327	457412.RSAG_02549	0.0	1119.0	COG0642@1|root,COG2199@1|root,COG2199@2|Bacteria,COG2205@2|Bacteria,1UQA9@1239|Firmicutes,24G0P@186801|Clostridia,3WSRV@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_9
HGCANGJP_01328	1121115.AXVN01000008_gene2676	1.01e-225	622.0	COG0583@1|root,COG0583@2|Bacteria,1V5MW@1239|Firmicutes,24J0X@186801|Clostridia,3Y0IH@572511|Blautia	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
HGCANGJP_01329	1121115.AXVN01000008_gene2675	1.62e-206	573.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZG8@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HGCANGJP_01330	1121115.AXVN01000008_gene2674	2.91e-196	545.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZRV@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HGCANGJP_01331	1121115.AXVN01000008_gene2673	0.0	1030.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3XZGV@572511|Blautia	186801|Clostridia	E	Psort location Cellwall, score	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HGCANGJP_01332	1121115.AXVN01000008_gene2672	4.82e-183	509.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,24B9N@186801|Clostridia,3XZCY@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_01333	1121115.AXVN01000008_gene2671	4.28e-176	491.0	COG4608@1|root,COG4608@2|Bacteria,1UV6D@1239|Firmicutes,25BCP@186801|Clostridia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_01334	411470.RUMGNA_01947	7.07e-112	327.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3Y01S@572511|Blautia	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HGCANGJP_01335	515620.EUBELI_20205	2.47e-270	746.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,25WGH@186806|Eubacteriaceae	186801|Clostridia	EG	gluconate H symporter	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
HGCANGJP_01336	515620.EUBELI_20204	5.38e-27	100.0	2DPN0@1|root,332QI@2|Bacteria,1VH4E@1239|Firmicutes,24R2M@186801|Clostridia	186801|Clostridia	S	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01337	457412.RSAG_01545	0.0	1102.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD3	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HGCANGJP_01338	457412.RSAG_01544	1.79e-218	607.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WI8G@541000|Ruminococcaceae	186801|Clostridia	H	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
HGCANGJP_01339	478749.BRYFOR_09258	2.28e-116	337.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
HGCANGJP_01340	457412.RSAG_02539	6.57e-119	340.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,3WIP4@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
HGCANGJP_01341	1121115.AXVN01000008_gene2666	1.48e-200	558.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,3Y2CN@572511|Blautia	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HGCANGJP_01342	457412.RSAG_02535	3.27e-294	804.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3WHPN@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
HGCANGJP_01343	457412.RSAG_02534	8.16e-154	431.0	COG2819@1|root,COG2819@2|Bacteria,1V1TT@1239|Firmicutes,24GDE@186801|Clostridia,3WIMM@541000|Ruminococcaceae	186801|Clostridia	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
HGCANGJP_01344	1121115.AXVN01000008_gene2663	3.01e-192	535.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3XZSJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
HGCANGJP_01345	1121115.AXVN01000008_gene2662	5.04e-39	129.0	COG4608@1|root,COG4608@2|Bacteria,1W0U9@1239|Firmicutes,252YQ@186801|Clostridia	186801|Clostridia	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01346	411461.DORFOR_02067	2.7e-193	540.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,27VKR@189330|Dorea	186801|Clostridia	EG	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HGCANGJP_01347	457412.RSAG_02530	1.59e-245	673.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WK39@541000|Ruminococcaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
HGCANGJP_01348	1121115.AXVN01000008_gene2659	0.0	952.0	COG1020@1|root,COG1020@2|Bacteria,1TQP2@1239|Firmicutes,24AMK@186801|Clostridia,3Y0AJ@572511|Blautia	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
HGCANGJP_01349	1121115.AXVN01000008_gene2658	8.84e-43	140.0	2DP4E@1|root,330GX@2|Bacteria,1VEZ7@1239|Firmicutes,24SE1@186801|Clostridia,3Y0WR@572511|Blautia	186801|Clostridia	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
HGCANGJP_01350	457412.RSAG_02527	0.0	1001.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia,3WI3M@541000|Ruminococcaceae	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
HGCANGJP_01351	457412.RSAG_02526	8.24e-137	387.0	COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,24G4C@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HGCANGJP_01352	1121115.AXVN01000163_gene910	2.44e-54	170.0	COG1396@1|root,COG1396@2|Bacteria,1VARC@1239|Firmicutes,24NFJ@186801|Clostridia,3Y0DI@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01353	1121115.AXVN01000163_gene909	1.29e-282	771.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,3Y049@572511|Blautia	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
HGCANGJP_01354	457412.RSAG_02523	2.13e-111	320.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24HI8@186801|Clostridia,3WIP1@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
HGCANGJP_01355	457412.RSAG_02522	1.47e-131	374.0	COG1102@1|root,COG1102@2|Bacteria,1UXGP@1239|Firmicutes,259Y0@186801|Clostridia,3WQJG@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_01356	457412.RSAG_02521	1.52e-175	491.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia,3WNCH@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
HGCANGJP_01357	411470.RUMGNA_02829	2.76e-171	518.0	COG1409@1|root,COG1409@2|Bacteria,1TSSR@1239|Firmicutes,248DJ@186801|Clostridia,3Y0EJ@572511|Blautia	186801|Clostridia	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,SLH
HGCANGJP_01358	411470.RUMGNA_02828	5.3e-133	392.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3Y0R0@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Sortase,YibE_F
HGCANGJP_01359	518637.EUBIFOR_00794	1.3e-151	430.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
HGCANGJP_01360	1121115.AXVN01000001_gene1050	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3Y0K6@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
HGCANGJP_01361	1121115.AXVN01000001_gene1049	0.0	1052.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3XZ8D@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HGCANGJP_01362	457412.RSAG_01068	1.64e-283	775.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HGCANGJP_01363	457412.RSAG_01067	6.3e-251	688.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3WI4Q@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
HGCANGJP_01364	457412.RSAG_01066	1.5e-197	547.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJK2@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
HGCANGJP_01365	1121115.AXVN01000001_gene1045	4.82e-186	518.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3XYTH@572511|Blautia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
HGCANGJP_01366	457412.RSAG_01064	1.94e-129	368.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WJD2@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
HGCANGJP_01367	1121115.AXVN01000001_gene1043	2.32e-190	528.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3Y02I@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
HGCANGJP_01368	457412.RSAG_01061	2.83e-302	823.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HGCANGJP_01369	457412.RSAG_01060	1.81e-179	500.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3WJBW@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
HGCANGJP_01370	411469.EUBHAL_00665	1.44e-185	532.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia	186801|Clostridia	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
HGCANGJP_01371	411469.EUBHAL_00664	1.18e-69	215.0	COG4393@1|root,COG4393@2|Bacteria,1V670@1239|Firmicutes,24HZF@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
HGCANGJP_01372	457412.RSAG_01059	2.61e-206	572.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,3WJ83@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_01373	457412.RSAG_01058	2.74e-206	570.0	COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,248RM@186801|Clostridia,3WN3B@541000|Ruminococcaceae	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HGCANGJP_01374	457412.RSAG_01057	0.0	1267.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae	186801|Clostridia	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
HGCANGJP_01375	457412.RSAG_01056	1.71e-207	574.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WI65@541000|Ruminococcaceae	186801|Clostridia	C	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HGCANGJP_01376	457412.RSAG_01055	2.56e-271	744.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia,3WKIP@541000|Ruminococcaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
HGCANGJP_01377	457412.RSAG_01054	0.0	882.0	COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,249RX@186801|Clostridia,3WSRN@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	BenE
HGCANGJP_01378	457412.RSAG_01053	7.29e-64	194.0	2B2ZF@1|root,32PN8@2|Bacteria,1V7B5@1239|Firmicutes,24JQY@186801|Clostridia,3WKHW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01379	457412.RSAG_01052	4.89e-63	192.0	29PJD@1|root,30AHI@2|Bacteria,1VC64@1239|Firmicutes,24N2Y@186801|Clostridia,3WQ27@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
HGCANGJP_01380	457412.RSAG_01051	0.0	1174.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,25KDV@186801|Clostridia,3WPDU@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
HGCANGJP_01381	457412.RSAG_01050	2.6e-233	641.0	COG0407@1|root,COG0407@2|Bacteria,1TNYE@1239|Firmicutes,25NJX@186801|Clostridia,3WQG7@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
HGCANGJP_01382	457412.RSAG_01049	2.34e-303	827.0	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,2496C@186801|Clostridia,3WK4C@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_01383	1121115.AXVN01000019_gene178	6.96e-207	572.0	COG1175@1|root,COG1175@2|Bacteria,1TQB1@1239|Firmicutes,25C4P@186801|Clostridia,3XZG3@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HGCANGJP_01384	457412.RSAG_01047	4.65e-194	539.0	COG0395@1|root,COG0395@2|Bacteria,1UYHV@1239|Firmicutes,25C4Q@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_01385	457412.RSAG_01046	0.0	992.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia,3WJQQ@541000|Ruminococcaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_18,Response_reg
HGCANGJP_01386	1121115.AXVN01000019_gene175	0.0	959.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3Y17X@572511|Blautia	186801|Clostridia	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
HGCANGJP_01387	457412.RSAG_01044	9.71e-224	616.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,3WHCX@541000|Ruminococcaceae	186801|Clostridia	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HGCANGJP_01388	1121115.AXVN01000019_gene173	1.22e-282	778.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3XYV4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
HGCANGJP_01389	457412.RSAG_01042	6.53e-171	478.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3WIPP@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
HGCANGJP_01390	457412.RSAG_01041	2.64e-210	581.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HGCANGJP_01391	457412.RSAG_01040	0.0	1326.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WJT6@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
HGCANGJP_01392	457412.RSAG_01038	0.0	919.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
HGCANGJP_01393	457412.RSAG_01037	3.77e-129	371.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia,3WJXG@541000|Ruminococcaceae	186801|Clostridia	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
HGCANGJP_01394	1121115.AXVN01000019_gene167	7.37e-54	171.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
HGCANGJP_01395	1121115.AXVN01000019_gene166	3.46e-265	727.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3XZ7I@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
HGCANGJP_01396	457412.RSAG_01034	0.0	924.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
HGCANGJP_01397	457412.RSAG_01033	3.85e-315	859.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WGDB@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HGCANGJP_01398	1121115.AXVN01000019_gene163	1.27e-144	409.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3XZMG@572511|Blautia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
HGCANGJP_01399	457412.RSAG_04679	6.76e-213	587.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,3WI4G@541000|Ruminococcaceae	186801|Clostridia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
HGCANGJP_01400	457412.RSAG_01031	2.98e-247	680.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
HGCANGJP_01401	457412.RSAG_01030	1.91e-181	504.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3WK04@541000|Ruminococcaceae	186801|Clostridia	GM	capsular polysaccharide biosynthesis protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
HGCANGJP_01402	457412.RSAG_01029	1.35e-166	468.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24G4J@186801|Clostridia,3WRUK@541000|Ruminococcaceae	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
HGCANGJP_01403	457412.RSAG_04680	4.65e-167	467.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,3WI2V@541000|Ruminococcaceae	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
HGCANGJP_01404	457412.RSAG_01028	2.29e-193	540.0	2E1XM@1|root,32X6K@2|Bacteria,1VCEM@1239|Firmicutes,24NS0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01405	457412.RSAG_01027	9.17e-223	617.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia,3WJFR@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HGCANGJP_01406	457412.RSAG_01026	8.36e-138	390.0	2EB5C@1|root,335VY@2|Bacteria,1VI1F@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01407	1121115.AXVN01000044_gene2027	2.15e-73	224.0	COG0250@1|root,COG0250@2|Bacteria,1V3BF@1239|Firmicutes,24G49@186801|Clostridia	186801|Clostridia	K	Transcription termination	-	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HGCANGJP_01408	457412.RSAG_01024	0.0	946.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3WHG7@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
HGCANGJP_01409	457412.RSAG_01023	4.49e-185	514.0	COG1922@1|root,COG1922@2|Bacteria,1UIHR@1239|Firmicutes,25BDH@186801|Clostridia,3WS61@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	CoA_binding_3,Glyco_tran_WecB
HGCANGJP_01410	1266845.Q783_07015	1.95e-132	392.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes	1239|Firmicutes	M	Glycosyltransferase, group 1 family protein	rfaG3	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
HGCANGJP_01412	1304885.AUEY01000015_gene2975	2.92e-29	126.0	COG0125@1|root,COG0125@2|Bacteria,1NXCJ@1224|Proteobacteria	1224|Proteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Thymidylate_kin
HGCANGJP_01413	180332.JTGN01000005_gene3056	6.79e-74	243.0	COG0438@1|root,COG0438@2|Bacteria,1UBCE@1239|Firmicutes,24DYC@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HGCANGJP_01414	1121101.HMPREF1532_00091	2.31e-51	176.0	COG1216@1|root,COG1216@2|Bacteria,4NGHQ@976|Bacteroidetes,2G0BP@200643|Bacteroidia,4AV56@815|Bacteroidaceae	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
HGCANGJP_01416	1500301.JQMF01000001_gene85	1.24e-05	55.8	COG3307@1|root,COG3307@2|Bacteria,1N0EK@1224|Proteobacteria,2UCUX@28211|Alphaproteobacteria,4B9IT@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	O-Antigen ligase	exoQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16567	-	-	-	-	ko00000	-	-	-	Wzy_C
HGCANGJP_01417	388467.A19Y_1081	7.87e-49	181.0	COG0438@1|root,COG1215@1|root,COG1216@1|root,COG3914@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,COG3914@2|Bacteria,1FZUY@1117|Cyanobacteria,1H72J@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23
HGCANGJP_01418	1226325.HMPREF1548_04602	1.35e-169	493.0	COG2244@1|root,COG2244@2|Bacteria,1TPSH@1239|Firmicutes,2492X@186801|Clostridia,36FXH@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
HGCANGJP_01421	397287.C807_03643	4.12e-86	284.0	2BCHK@1|root,3263H@2|Bacteria,1US2N@1239|Firmicutes,24YAW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01422	397287.C807_03642	3.54e-62	207.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
HGCANGJP_01423	445970.ALIPUT_00300	4.67e-15	77.8	COG5423@1|root,COG5423@2|Bacteria,4NSZ1@976|Bacteroidetes,2FMDP@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
HGCANGJP_01425	457412.RSAG_04683	0.0	1951.0	COG1208@1|root,COG2605@1|root,COG1208@2|Bacteria,COG2605@2|Bacteria,1VU5A@1239|Firmicutes,24BK8@186801|Clostridia,3WJ16@541000|Ruminococcaceae	186801|Clostridia	JM	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HGCANGJP_01426	457412.RSAG_01004	3.93e-216	595.0	COG2207@1|root,COG2207@2|Bacteria,1V1VJ@1239|Firmicutes,24G3A@186801|Clostridia,3WRI1@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_01427	457412.RSAG_01003	1.45e-259	710.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia,3WHBN@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
HGCANGJP_01428	457412.RSAG_01002	8.4e-234	642.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia,3WH5N@541000|Ruminococcaceae	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
HGCANGJP_01429	457412.RSAG_01001	0.0	867.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,3WI9R@541000|Ruminococcaceae	186801|Clostridia	M	Mannose-1-phosphate guanylyltransferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
HGCANGJP_01430	457412.RSAG_04684	1.08e-243	668.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia,3WRRD@541000|Ruminococcaceae	186801|Clostridia	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
HGCANGJP_01431	457412.RSAG_04685	0.0	1081.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HGCANGJP_01432	1235799.C818_01943	2.35e-136	401.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,27M2S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
HGCANGJP_01433	1232452.BAIB02000013_gene2258	2.63e-21	92.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HGCANGJP_01434	457412.RSAG_01024	1.86e-251	698.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3WHG7@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
HGCANGJP_01436	742765.HMPREF9457_02807	0.0	1033.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,27VAI@189330|Dorea	186801|Clostridia	GM	RmlD substrate binding domain	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
HGCANGJP_01437	1160721.RBI_I00597	1.95e-316	861.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3WI7G@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
HGCANGJP_01438	887325.HMPREF0381_2024	3.2e-121	353.0	COG2148@1|root,COG2148@2|Bacteria,1TP49@1239|Firmicutes,249F1@186801|Clostridia,1HWD6@1164882|Lachnoanaerobaculum	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Glycos_transf_2
HGCANGJP_01439	1160721.RBI_I00598	4.69e-117	351.0	COG0463@1|root,COG2148@1|root,COG0463@2|Bacteria,COG2148@2|Bacteria,1TP49@1239|Firmicutes,249F1@186801|Clostridia,3WGJ8@541000|Ruminococcaceae	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,Glycos_transf_2
HGCANGJP_01442	746697.Aeqsu_2919	1.34e-15	74.7	COG0110@1|root,COG0110@2|Bacteria,4NQQG@976|Bacteroidetes,1I3DQ@117743|Flavobacteriia	976|Bacteroidetes	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HGCANGJP_01443	865937.Gilli_0685	4.53e-21	104.0	COG0438@1|root,COG0438@2|Bacteria,4NMR6@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
HGCANGJP_01445	1077285.AGDG01000032_gene4421	7.41e-60	204.0	COG1143@1|root,COG1143@2|Bacteria,4PMG7@976|Bacteroidetes,2G0JG@200643|Bacteroidia,4AV9G@815|Bacteroidaceae	976|Bacteroidetes	C	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
HGCANGJP_01446	1301100.HG529227_gene5469	4.74e-80	266.0	COG0728@1|root,COG0728@2|Bacteria,1TPFI@1239|Firmicutes,247N3@186801|Clostridia,36FH2@31979|Clostridiaceae	186801|Clostridia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
HGCANGJP_01447	37919.EP51_08405	2.81e-29	112.0	COG0110@1|root,COG0110@2|Bacteria,2GTYF@201174|Actinobacteria,4G8JH@85025|Nocardiaceae	201174|Actinobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
HGCANGJP_01448	457412.RSAG_01020	3.95e-73	241.0	COG1035@1|root,COG1143@1|root,COG1035@2|Bacteria,COG1143@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,3WIVM@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N
HGCANGJP_01449	1408287.AXUR01000004_gene1988	2.55e-26	113.0	COG0110@1|root,COG2089@1|root,COG0110@2|Bacteria,COG2089@2|Bacteria,379XE@32066|Fusobacteria	32066|Fusobacteria	M	SAF	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
HGCANGJP_01450	411470.RUMGNA_01827	8.41e-133	389.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia	186801|Clostridia	M	synthase	neuB	-	2.5.1.101,2.5.1.56	ko:K01654,ko:K18430	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R10304	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
HGCANGJP_01451	203119.Cthe_2639	1.23e-91	275.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,24G5I@186801|Clostridia,3WK7R@541000|Ruminococcaceae	186801|Clostridia	M	Cytidylyltransferase	neuA	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
HGCANGJP_01452	411470.RUMGNA_01825	7.94e-147	428.0	COG0381@1|root,COG0381@2|Bacteria,1TQKQ@1239|Firmicutes,24A0H@186801|Clostridia	186801|Clostridia	M	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing	neuC	-	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
HGCANGJP_01453	411459.RUMOBE_02913	4.34e-281	770.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,3XZF2@572511|Blautia	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_3,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
HGCANGJP_01454	411459.RUMOBE_02914	0.0	1100.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HGCANGJP_01455	525255.HMPREF0077_1024	1.3e-36	143.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,247Z9@186801|Clostridia,22I10@1570339|Peptoniphilaceae	186801|Clostridia	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
HGCANGJP_01457	411459.RUMOBE_02914	7.89e-27	108.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
HGCANGJP_01459	457412.RSAG_00991	7.29e-61	187.0	COG1813@1|root,COG1813@2|Bacteria,1UI13@1239|Firmicutes,25FPX@186801|Clostridia,3WSNY@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01460	478749.BRYFOR_09314	2.77e-126	370.0	COG2333@1|root,COG2333@2|Bacteria,1VWU3@1239|Firmicutes,24RH9@186801|Clostridia	186801|Clostridia	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HGCANGJP_01462	1121115.AXVN01000036_gene2435	4.52e-17	79.3	COG5421@1|root,COG5421@2|Bacteria,1UHBN@1239|Firmicutes,249CH@186801|Clostridia,3Y11E@572511|Blautia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_01463	457412.RSAG_00970	3.99e-269	745.0	COG5421@1|root,COG5421@2|Bacteria,1UHBN@1239|Firmicutes,249CH@186801|Clostridia,3WPID@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_01464	457412.RSAG_00969	5.33e-44	143.0	2EJPA@1|root,33DE4@2|Bacteria,1VPMV@1239|Firmicutes,24VGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01465	1121115.AXVN01000091_gene2616	1.27e-56	185.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HGCANGJP_01466	1121115.AXVN01000091_gene2616	3.81e-64	205.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HGCANGJP_01467	865861.AZSU01000002_gene2613	4.53e-77	260.0	2C9CN@1|root,2ZFFI@2|Bacteria,1VUK9@1239|Firmicutes,250GY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01469	457412.RSAG_00966	4.49e-297	811.0	2DEDR@1|root,2ZMJC@2|Bacteria,1V31W@1239|Firmicutes,24FHB@186801|Clostridia,3WPN4@541000|Ruminococcaceae	186801|Clostridia	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
HGCANGJP_01470	457412.RSAG_00965	0.0	1372.0	COG3972@1|root,COG3972@2|Bacteria,1U80C@1239|Firmicutes,24EBG@186801|Clostridia,3WKQH@541000|Ruminococcaceae	186801|Clostridia	S	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
HGCANGJP_01471	457412.RSAG_00964	2.15e-158	443.0	COG5619@1|root,COG5619@2|Bacteria,1VATP@1239|Firmicutes,24Q9K@186801|Clostridia,3WPND@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized conserved protein (DUF2290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2290
HGCANGJP_01472	1121115.AXVN01000077_gene2642	4.34e-22	87.4	2C9RV@1|root,32UDR@2|Bacteria,1VD3D@1239|Firmicutes,24NEV@186801|Clostridia,3Y1XJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01473	1121115.AXVN01000077_gene2644	1.13e-87	258.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,3Y1QS@572511|Blautia	186801|Clostridia	H	Aspartate decarboxylase	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
HGCANGJP_01474	1121115.AXVN01000077_gene2645	2.24e-200	555.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3Y13Y@572511|Blautia	186801|Clostridia	H	Pantoate-beta-alanine ligase	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
HGCANGJP_01475	1121115.AXVN01000077_gene2646	2.44e-219	607.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3Y1N1@572511|Blautia	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
HGCANGJP_01476	1121115.AXVN01000077_gene2647	6.26e-92	268.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,25NF4@186801|Clostridia,3Y0JQ@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HGCANGJP_01477	1121115.AXVN01000035_gene3825	8.96e-10	60.1	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3XZ2T@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
HGCANGJP_01478	1121115.AXVN01000077_gene2649	7.48e-188	521.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3XZY2@572511|Blautia	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
HGCANGJP_01479	457412.RSAG_00958	0.0	926.0	COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,24C6R@186801|Clostridia,3WNTJ@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
HGCANGJP_01480	457412.RSAG_00957	0.0	1880.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WGSH@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	ADC,Oxidored_FMN,Pyr_redox_2
HGCANGJP_01481	457412.RSAG_00956	1.38e-171	479.0	COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24DU0@186801|Clostridia,3WS77@541000|Ruminococcaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
HGCANGJP_01482	1121115.AXVN01000037_gene3266	0.0	1495.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3XYPZ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
HGCANGJP_01483	457412.RSAG_01390	5.46e-169	471.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3WHF8@541000|Ruminococcaceae	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HGCANGJP_01484	1121115.AXVN01000037_gene3264	1.06e-257	707.0	COG1879@1|root,COG1879@2|Bacteria,1UZFA@1239|Firmicutes,249QV@186801|Clostridia,3XYTX@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	rbsB_4	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
HGCANGJP_01485	1121115.AXVN01000037_gene3263	2.9e-56	175.0	2EC1A@1|root,3360H@2|Bacteria,1VHMT@1239|Firmicutes,24S6Y@186801|Clostridia,3Y1SK@572511|Blautia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
HGCANGJP_01486	1121115.AXVN01000037_gene3262	7.79e-93	271.0	2BAXA@1|root,324CZ@2|Bacteria,1UQP9@1239|Firmicutes,258FM@186801|Clostridia,3Y1K7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01487	457412.RSAG_04512	1.81e-172	482.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
HGCANGJP_01488	1121115.AXVN01000037_gene3260	1.25e-56	176.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y1RW@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
HGCANGJP_01489	1121115.AXVN01000037_gene3259	1.94e-91	270.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,258VV@186801|Clostridia,3Y0ZV@572511|Blautia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_B
HGCANGJP_01490	457412.RSAG_01381	1.5e-119	342.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24JWN@186801|Clostridia,3WS23@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
HGCANGJP_01491	1121115.AXVN01000037_gene3257	0.0	976.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3Y1A3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
HGCANGJP_01492	1121115.AXVN01000037_gene3256	8.05e-197	546.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3Y0ZD@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
HGCANGJP_01493	1121115.AXVN01000037_gene3255	0.0	909.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3Y1D7@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
HGCANGJP_01494	1121115.AXVN01000037_gene3254	1.73e-89	262.0	COG0355@1|root,COG0355@2|Bacteria,1TTR7@1239|Firmicutes,25MVC@186801|Clostridia,3Y1KM@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_DE,ATP-synt_DE_N
HGCANGJP_01495	457412.RSAG_01375	8.68e-44	142.0	29UA8@1|root,3489I@2|Bacteria,1VZGI@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01496	457412.RSAG_01374	5.75e-147	413.0	COG0500@1|root,COG2226@2|Bacteria,1TVU2@1239|Firmicutes,24AIJ@186801|Clostridia,3WJ6T@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
HGCANGJP_01497	457412.RSAG_04508	3.35e-105	303.0	COG0454@1|root,COG0456@2|Bacteria,1V3IC@1239|Firmicutes,24HK5@186801|Clostridia,3WJ6B@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,Acetyltransf_7
HGCANGJP_01498	457412.RSAG_04637	5.71e-48	153.0	2EA3V@1|root,3348U@2|Bacteria,1VFVI@1239|Firmicutes,24RVZ@186801|Clostridia,3WQVA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01499	411459.RUMOBE_01921	8.39e-78	231.0	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HGCANGJP_01500	1280698.AUJS01000042_gene3268	6.83e-76	226.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,25NNG@186801|Clostridia,27X9B@189330|Dorea	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
HGCANGJP_01501	411459.RUMOBE_02225	6.43e-88	258.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,3Y0NF@572511|Blautia	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
HGCANGJP_01502	1121115.AXVN01000037_gene3253	2.17e-286	782.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3XZCR@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
HGCANGJP_01503	1121115.AXVN01000037_gene3252	5.56e-308	841.0	COG1070@1|root,COG1070@2|Bacteria,1TSEJ@1239|Firmicutes,24AT3@186801|Clostridia,3Y1CK@572511|Blautia	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
HGCANGJP_01504	1121115.AXVN01000037_gene3251	0.0	1132.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3Y19R@572511|Blautia	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HGCANGJP_01505	1121115.AXVN01000037_gene3250	4.78e-55	171.0	2DWC0@1|root,33ZIT@2|Bacteria,1VY40@1239|Firmicutes,252ED@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01506	97139.C824_00876	4.93e-16	75.5	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01507	626939.HMPREF9443_00988	8.32e-78	238.0	2DC3T@1|root,2ZCSW@2|Bacteria,1W4K9@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01508	500632.CLONEX_02762	1.3e-146	413.0	COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,24ACT@186801|Clostridia	186801|Clostridia	S	IA, variant 1	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HGCANGJP_01509	500632.CLONEX_02763	4.37e-147	414.0	COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,2496B@186801|Clostridia	186801|Clostridia	F	Hydrolase, nudix family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
HGCANGJP_01510	500632.CLONEX_02764	5.17e-179	499.0	COG3093@1|root,COG3093@2|Bacteria,1UXZS@1239|Firmicutes,24BNR@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01511	411462.DORLON_00490	2.77e-93	274.0	28NID@1|root,2ZBYW@2|Bacteria,1V1SS@1239|Firmicutes,257MZ@186801|Clostridia,27VT9@189330|Dorea	186801|Clostridia	S	Cysteine-rich VLP	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_VLP
HGCANGJP_01512	411462.DORLON_00493	9.84e-212	586.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,247S8@186801|Clostridia,27V0D@189330|Dorea	186801|Clostridia	D	COG NOG17369 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HGCANGJP_01513	658659.HMPREF0983_00052	3.8e-39	130.0	2C3T4@1|root,32S28@2|Bacteria,1VB78@1239|Firmicutes,3VTWK@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01514	658659.HMPREF0983_00051	0.0	1023.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,3VP5W@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_01516	457412.RSAG_02211	2.61e-236	650.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WM8X@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
HGCANGJP_01517	457412.RSAG_02212	9.69e-274	748.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WICI@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
HGCANGJP_01518	1121115.AXVN01000037_gene3247	0.0	1065.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
HGCANGJP_01519	1121115.AXVN01000037_gene3246	2.88e-17	75.9	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
HGCANGJP_01520	457412.RSAG_02214	5.85e-77	230.0	2CFUE@1|root,33V7A@2|Bacteria,1VUR9@1239|Firmicutes,250BS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01521	457412.RSAG_02215	3.88e-118	338.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,3WIVQ@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
HGCANGJP_01522	457412.RSAG_02216	7.3e-246	676.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,3WHMJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
HGCANGJP_01523	457412.RSAG_02217	0.0	1050.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3WGSV@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
HGCANGJP_01524	1121115.AXVN01000037_gene3241	1e-253	697.0	COG3347@1|root,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,25BHR@186801|Clostridia,3Y16D@572511|Blautia	186801|Clostridia	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
HGCANGJP_01525	1121115.AXVN01000037_gene3240	0.0	1729.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
HGCANGJP_01526	1121115.AXVN01000103_gene866	3.19e-66	201.0	COG1879@1|root,COG1879@2|Bacteria,1VX4B@1239|Firmicutes,251P0@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01527	1121115.AXVN01000103_gene865	6.46e-83	245.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes	1239|Firmicutes	K	repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HGCANGJP_01528	457412.RSAG_02805	1.92e-159	446.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia,3WIY4@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
HGCANGJP_01529	457412.RSAG_02804	0.0	1403.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia,3WI61@541000|Ruminococcaceae	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
HGCANGJP_01530	457412.RSAG_02803	0.0	1382.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia,3WKD2@541000|Ruminococcaceae	186801|Clostridia	GM	Domain of unknown function (DUF4118)	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
HGCANGJP_01531	457412.RSAG_02802	4.17e-205	568.0	28H6W@1|root,2Z7J7@2|Bacteria,1TPV9@1239|Firmicutes,24CD2@186801|Clostridia,3WMQ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01532	457412.RSAG_02801	0.0	1233.0	COG4878@1|root,COG4878@2|Bacteria,1TT2Y@1239|Firmicutes,24A4C@186801|Clostridia,3WIQH@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
HGCANGJP_01533	457412.RSAG_02800	0.0	987.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia,3WGGZ@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
HGCANGJP_01534	457412.RSAG_02799	0.0	938.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia,3WKMX@541000|Ruminococcaceae	186801|Clostridia	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
HGCANGJP_01535	457412.RSAG_02798	0.0	1199.0	COG5337@1|root,COG5337@2|Bacteria,1U5H9@1239|Firmicutes,249YX@186801|Clostridia,3WI9H@541000|Ruminococcaceae	186801|Clostridia	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
HGCANGJP_01536	457412.RSAG_02797	6.38e-181	503.0	COG5036@1|root,COG5036@2|Bacteria,1TYFN@1239|Firmicutes,24AGZ@186801|Clostridia,3WJCF@541000|Ruminococcaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
HGCANGJP_01537	457412.RSAG_02796	2.78e-148	418.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3WHWK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
HGCANGJP_01538	457412.RSAG_02795	0.0	941.0	COG1874@1|root,COG1874@2|Bacteria,1TRPS@1239|Firmicutes,24AH9@186801|Clostridia,3WIPR@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_42
HGCANGJP_01539	457412.RSAG_02794	8.26e-274	748.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,3WK14@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
HGCANGJP_01540	457412.RSAG_02793	1.29e-277	760.0	COG1609@1|root,COG1609@2|Bacteria,1UZFZ@1239|Firmicutes,24H13@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01541	457412.RSAG_02792	0.0	1034.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HGCANGJP_01542	457412.RSAG_02791	1.72e-216	598.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WN70@541000|Ruminococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HGCANGJP_01543	457412.RSAG_02790	5.2e-188	523.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIZI@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15586	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
HGCANGJP_01544	457412.RSAG_04542	9.73e-181	503.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WNXH@541000|Ruminococcaceae	186801|Clostridia	EP	ATPases associated with a variety of cellular activities	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
HGCANGJP_01545	457412.RSAG_04541	6.62e-231	635.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN6I@541000|Ruminococcaceae	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
HGCANGJP_01546	457412.RSAG_02788	1.18e-307	840.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01547	457412.RSAG_02787	4.15e-46	148.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HGCANGJP_01548	457412.RSAG_02786	0.0	1174.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HGCANGJP_01549	457412.RSAG_02785	1.55e-79	236.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	czrA	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HGCANGJP_01550	457412.RSAG_02784	9.83e-260	712.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3WJ0E@541000|Ruminococcaceae	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
HGCANGJP_01551	1121115.AXVN01000103_gene855	4.58e-119	340.0	COG5423@1|root,COG5423@2|Bacteria,1VBHK@1239|Firmicutes,24XGW@186801|Clostridia,3Y0MP@572511|Blautia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
HGCANGJP_01552	457412.RSAG_02782	8.61e-75	223.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
HGCANGJP_01553	457412.RSAG_02781	1.86e-89	262.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24RT7@186801|Clostridia,3WMCM@541000|Ruminococcaceae	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
HGCANGJP_01554	457412.RSAG_02780	1e-137	389.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia,3WRWC@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HGCANGJP_01555	457412.RSAG_02779	1.55e-272	746.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHER@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
HGCANGJP_01556	457412.RSAG_02778	1.06e-146	413.0	COG2357@1|root,COG2357@2|Bacteria,1UZBZ@1239|Firmicutes,24FD2@186801|Clostridia,3WJCI@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HGCANGJP_01557	457412.RSAG_02777	0.0	1071.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3WJUQ@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
HGCANGJP_01558	1121115.AXVN01000012_gene3143	0.0	1221.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
HGCANGJP_01559	1121115.AXVN01000012_gene3142	1.72e-269	740.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,3XZFH@572511|Blautia	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
HGCANGJP_01560	1235802.C823_05668	1.87e-43	142.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
HGCANGJP_01561	457412.RSAG_02755	7.3e-210	578.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,3WJRY@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
HGCANGJP_01562	1121115.AXVN01000018_gene63	5.1e-43	142.0	2EC7P@1|root,33668@2|Bacteria,1VHK0@1239|Firmicutes,24R0C@186801|Clostridia,3Y0UW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01563	1121115.AXVN01000018_gene64	2.61e-161	451.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3XZ71@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
HGCANGJP_01565	457412.RSAG_01617	0.0	907.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,3WHXK@541000|Ruminococcaceae	186801|Clostridia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
HGCANGJP_01566	1121115.AXVN01000018_gene67	0.0	1660.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XZ46@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
HGCANGJP_01567	457412.RSAG_01615	0.0	1051.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
HGCANGJP_01568	938289.CAJN020000001_gene1164	8.42e-115	329.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,26B2Y@186813|unclassified Clostridiales	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HGCANGJP_01569	428125.CLOLEP_03211	6.81e-34	116.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,3WM8N@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01570	938289.CAJN020000001_gene1165	9.56e-267	729.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,2689P@186813|unclassified Clostridiales	186801|Clostridia	L	Site-specific recombinase, phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HGCANGJP_01571	411460.RUMTOR_02161	1.43e-64	197.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,25MZ5@186801|Clostridia,3Y0P8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01572	478749.BRYFOR_06470	4.53e-245	676.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia	186801|Clostridia	L	COG NOG19743 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
HGCANGJP_01573	428125.CLOLEP_03219	6.18e-201	565.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HGCANGJP_01574	938289.CAJN020000001_gene1169	1.3e-87	257.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,24IHH@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_01575	1280696.ATVY01000024_gene1018	4.92e-259	723.0	COG0488@1|root,COG0488@2|Bacteria,1TU6J@1239|Firmicutes,24APJ@186801|Clostridia,4BX94@830|Butyrivibrio	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_01576	679937.Bcop_0088	1.9e-72	222.0	COG0617@1|root,COG0617@2|Bacteria,4NZY6@976|Bacteroidetes,2FQ7N@200643|Bacteroidia,4ARIS@815|Bacteroidaceae	976|Bacteroidetes	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	Aminoglyc_resit
HGCANGJP_01577	742740.HMPREF9474_03275	9.39e-231	640.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,220KX@1506553|Lachnoclostridium	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,HTH_3
HGCANGJP_01578	742740.HMPREF9474_03276	1.45e-216	605.0	2C4CB@1|root,2Z7XX@2|Bacteria,1V8K4@1239|Firmicutes,24NW3@186801|Clostridia	186801|Clostridia	L	EcoRII C terminal	-	-	-	-	-	-	-	-	-	-	-	-	EcoRII-C,EcoRII-N
HGCANGJP_01579	742740.HMPREF9474_03277	2.09e-75	228.0	COG3727@1|root,COG3727@2|Bacteria,1VA1Q@1239|Firmicutes,25AZ7@186801|Clostridia,2246G@1506553|Lachnoclostridium	186801|Clostridia	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
HGCANGJP_01580	1487923.DP73_03155	5.29e-217	625.0	COG0497@1|root,COG3593@1|root,COG0497@2|Bacteria,COG3593@2|Bacteria,1VCSI@1239|Firmicutes,24TJZ@186801|Clostridia,26370@186807|Peptococcaceae	186801|Clostridia	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15
HGCANGJP_01581	720554.Clocl_0183	3.25e-62	206.0	2BU13@1|root,32P9R@2|Bacteria,1V8XK@1239|Firmicutes,24M09@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01582	720554.Clocl_0184	3.97e-103	315.0	COG3344@1|root,COG3344@2|Bacteria,1UZGS@1239|Firmicutes,247Z6@186801|Clostridia,3WIXG@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
HGCANGJP_01584	397291.C804_03695	5.87e-294	803.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,27IGC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HGCANGJP_01585	411461.DORFOR_01989	1.22e-80	243.0	COG1476@1|root,COG1476@2|Bacteria,1V7I5@1239|Firmicutes,24KRY@186801|Clostridia,27WTV@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01586	411461.DORFOR_01990	6.29e-250	686.0	COG1396@1|root,COG1396@2|Bacteria,1V5AK@1239|Firmicutes,25EWQ@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01587	411461.DORFOR_01992	1.34e-51	162.0	COG2161@1|root,COG2161@2|Bacteria,1VA5D@1239|Firmicutes,24NDD@186801|Clostridia	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
HGCANGJP_01588	1410674.JNKU01000050_gene1928	4.36e-49	157.0	COG3668@1|root,COG3668@2|Bacteria,1VGR8@1239|Firmicutes	1239|Firmicutes	S	Addiction module toxin RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
HGCANGJP_01589	471875.RUMLAC_01450	1.17e-186	525.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24EQM@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HGCANGJP_01590	471875.RUMLAC_01449	6.53e-36	122.0	2DPW7@1|root,333NJ@2|Bacteria,1TUXF@1239|Firmicutes,25NXH@186801|Clostridia,3WQNR@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3173
HGCANGJP_01591	411459.RUMOBE_02513	1.08e-51	162.0	2AJW5@1|root,32RUV@2|Bacteria,1UHK2@1239|Firmicutes,24TE6@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
HGCANGJP_01592	471875.RUMLAC_01446	9.58e-90	264.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,24FTZ@186801|Clostridia,3WSS6@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
HGCANGJP_01593	411469.EUBHAL_01614	2.41e-313	855.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,25UVF@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
HGCANGJP_01594	411469.EUBHAL_01613	1.37e-151	427.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25VYC@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_01595	411469.EUBHAL_01612	6.07e-185	515.0	28JBR@1|root,2Z96E@2|Bacteria,1V0A1@1239|Firmicutes,24D16@186801|Clostridia,25Y22@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	ko:K20489	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	-
HGCANGJP_01596	411459.RUMOBE_02508	5.01e-170	475.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
HGCANGJP_01597	411469.EUBHAL_01610	1.13e-165	464.0	COG4200@1|root,COG4200@2|Bacteria,1V78D@1239|Firmicutes,25D9T@186801|Clostridia,25V0J@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	mutE	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
HGCANGJP_01598	411459.RUMOBE_02506	2.39e-163	457.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3XZKN@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	mutF	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
HGCANGJP_01599	411459.RUMOBE_02505	3.57e-29	107.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,25BHS@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_01600	1121115.AXVN01000067_gene3467	1.34e-176	492.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
HGCANGJP_01601	457412.RSAG_01608	5.03e-177	493.0	COG4200@1|root,COG4200@2|Bacteria,1V78D@1239|Firmicutes,25D9T@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	mutE	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
HGCANGJP_01602	457412.RSAG_01607	1.82e-163	457.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3WHM4@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
HGCANGJP_01603	1280698.AUJS01000020_gene1392	5.32e-34	123.0	2EJ89@1|root,33CZF@2|Bacteria,1VNWZ@1239|Firmicutes,24RJS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01604	411459.RUMOBE_01821	1.43e-151	428.0	2DBS8@1|root,2ZAQF@2|Bacteria,1UY30@1239|Firmicutes,249BS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HGCANGJP_01605	457412.RSAG_00145	0.0	1701.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
HGCANGJP_01606	1121115.AXVN01000020_gene83	0.0	1317.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3XYSA@572511|Blautia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
HGCANGJP_01607	457412.RSAG_00143	6.54e-222	612.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
HGCANGJP_01608	1121115.AXVN01000020_gene85	1.05e-310	846.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3XZKZ@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
HGCANGJP_01609	457412.RSAG_00141	1.62e-277	759.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,3WHRI@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
HGCANGJP_01610	457412.RSAG_00140	0.0	1068.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3WGFA@541000|Ruminococcaceae	186801|Clostridia	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
HGCANGJP_01611	1121115.AXVN01000020_gene88	2.22e-171	478.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3XZVG@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
HGCANGJP_01612	1121115.AXVN01000020_gene89	1.2e-240	661.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,3XZ2N@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HGCANGJP_01613	457412.RSAG_00137	5.94e-208	576.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
HGCANGJP_01614	457412.RSAG_00136	8.38e-120	342.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,3WJYV@541000|Ruminococcaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
HGCANGJP_01615	457412.RSAG_00135	0.0	1858.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3WGCH@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
HGCANGJP_01616	1121115.AXVN01000020_gene93	3.12e-178	497.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3XZ45@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
HGCANGJP_01617	457412.RSAG_00133	1.38e-59	184.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,3WJJQ@541000|Ruminococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
HGCANGJP_01618	1121115.AXVN01000020_gene95	2.14e-245	677.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3XZJI@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
HGCANGJP_01619	457412.RSAG_00131	4.32e-279	764.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HGCANGJP_01620	1121115.AXVN01000020_gene97	2.05e-126	359.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia,3Y0IJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
HGCANGJP_01621	457412.RSAG_00129	6.89e-75	223.0	2F70J@1|root,33ZG8@2|Bacteria,1VX30@1239|Firmicutes,251WZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01622	457412.RSAG_00127	4.22e-45	145.0	2EPN8@1|root,33H8W@2|Bacteria,1VM4B@1239|Firmicutes,24VJ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01623	1121115.AXVN01000020_gene100	9.73e-55	171.0	COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,25CY3@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
HGCANGJP_01624	457412.RSAG_00125	4.54e-63	192.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia,3WJV4@541000|Ruminococcaceae	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
HGCANGJP_01625	1121115.AXVN01000020_gene101	1.97e-63	193.0	2DZYH@1|root,32VN8@2|Bacteria,1VB55@1239|Firmicutes,24P04@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
HGCANGJP_01626	457412.RSAG_00123	3.87e-155	435.0	2CX3M@1|root,32T12@2|Bacteria,1VTDD@1239|Firmicutes,24Z9E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01627	1121115.AXVN01000020_gene104	4.08e-117	335.0	2C2F1@1|root,33RFH@2|Bacteria,1VSIV@1239|Firmicutes,24ZQ7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01628	457412.RSAG_00121	8.07e-163	455.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WHDU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
HGCANGJP_01629	1121115.AXVN01000020_gene106	1.7e-92	270.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3Y046@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01630	1121115.AXVN01000020_gene107	5.13e-55	171.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,3Y20U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01631	1121115.AXVN01000020_gene108	7.46e-258	707.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,3XYHX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	xerS	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
HGCANGJP_01632	1121115.AXVN01000020_gene110	6.36e-98	284.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3Y0GI@572511|Blautia	186801|Clostridia	S	Thioesterase-like superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
HGCANGJP_01633	1121115.AXVN01000020_gene111	3.91e-237	667.0	COG4942@1|root,COG5263@1|root,COG4942@2|Bacteria,COG5263@2|Bacteria,1VH35@1239|Firmicutes,25KD3@186801|Clostridia,3Y04J@572511|Blautia	186801|Clostridia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_M23
HGCANGJP_01634	1121115.AXVN01000020_gene112	0.0	939.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3XZ5I@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HGCANGJP_01635	1121115.AXVN01000020_gene113	1.58e-153	431.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
HGCANGJP_01636	457412.RSAG_00112	8.26e-220	606.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HGCANGJP_01637	1121115.AXVN01000020_gene115	2.06e-119	341.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3Y0CB@572511|Blautia	186801|Clostridia	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
HGCANGJP_01638	457412.RSAG_00110	1.46e-261	716.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
HGCANGJP_01639	457412.RSAG_00109	1.83e-180	502.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
HGCANGJP_01640	1121115.AXVN01000020_gene118	5.64e-107	313.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3XZSZ@572511|Blautia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
HGCANGJP_01641	1121115.AXVN01000020_gene119	4.63e-161	451.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3XYQJ@572511|Blautia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
HGCANGJP_01642	457412.RSAG_00105	0.0	916.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,3WIPB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01643	1121115.AXVN01000003_gene1617	0.0	1009.0	COG0497@1|root,COG0497@2|Bacteria,1UJV8@1239|Firmicutes,25FAU@186801|Clostridia	186801|Clostridia	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
HGCANGJP_01644	1121115.AXVN01000003_gene1616	3.62e-185	519.0	COG2885@1|root,COG2885@2|Bacteria,1V6HB@1239|Firmicutes,24ARV@186801|Clostridia,3Y17K@572511|Blautia	186801|Clostridia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
HGCANGJP_01645	1121115.AXVN01000003_gene1615	5.65e-220	606.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZRD@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
HGCANGJP_01646	1121115.AXVN01000003_gene1614	1.64e-74	223.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
HGCANGJP_01647	1121115.AXVN01000003_gene1613	1.71e-138	392.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia,3XZTM@572511|Blautia	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HGCANGJP_01648	1121115.AXVN01000003_gene1612	1.46e-202	560.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3XYWP@572511|Blautia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
HGCANGJP_01649	1121115.AXVN01000003_gene1611	3.38e-172	481.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3XZF8@572511|Blautia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
HGCANGJP_01650	457412.RSAG_00628	1.6e-86	254.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WMJ4@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
HGCANGJP_01651	1121115.AXVN01000003_gene1609	1.12e-211	583.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3XYQB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
HGCANGJP_01652	457412.RSAG_00626	1.07e-283	775.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
HGCANGJP_01653	1121115.AXVN01000003_gene1607	0.0	917.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3XYRJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
HGCANGJP_01654	457412.RSAG_00624	2.91e-312	851.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
HGCANGJP_01655	1121115.AXVN01000003_gene1605	8.07e-148	416.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3XZ7V@572511|Blautia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
HGCANGJP_01656	1121115.AXVN01000003_gene1604	4.37e-241	663.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3XYNR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
HGCANGJP_01657	1121115.AXVN01000003_gene1603	1.45e-202	561.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3XYQK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
HGCANGJP_01658	457412.RSAG_00620	1.16e-68	209.0	2CEVS@1|root,30HAB@2|Bacteria,1UHCU@1239|Firmicutes,25Q3B@186801|Clostridia,3WR1K@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01659	1121115.AXVN01000003_gene1601	1.02e-34	118.0	2FK7C@1|root,34BV3@2|Bacteria,1W6KA@1239|Firmicutes,254TZ@186801|Clostridia,3Y0MF@572511|Blautia	186801|Clostridia	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
HGCANGJP_01660	1121115.AXVN01000003_gene1600	1.83e-183	510.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYPW@572511|Blautia	186801|Clostridia	D	cell division inhibitor, membrane ATPase MinD	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
HGCANGJP_01661	1121115.AXVN01000003_gene1599	0.0	1263.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3XZEI@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
HGCANGJP_01662	457412.RSAG_00616	4.82e-178	496.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,3WNTV@541000|Ruminococcaceae	186801|Clostridia	D	Anion-transporting ATPase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
HGCANGJP_01663	457412.RSAG_00615	0.0	1398.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
HGCANGJP_01664	1121115.AXVN01000003_gene1595	1.85e-212	588.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
HGCANGJP_01665	457412.RSAG_00613	0.0	880.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3WNR9@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
HGCANGJP_01666	457412.RSAG_00612	2.8e-185	515.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3WNXA@541000|Ruminococcaceae	186801|Clostridia	E	Pterin binding enzyme	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HGCANGJP_01667	457412.RSAG_00611	0.0	1286.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3WI2J@541000|Ruminococcaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
HGCANGJP_01668	1121115.AXVN01000003_gene1591	3.97e-162	453.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,3XZ4M@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
HGCANGJP_01669	457412.RSAG_00609	3.83e-139	394.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3WJ4I@541000|Ruminococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
HGCANGJP_01670	1121115.AXVN01000003_gene1589	1.91e-199	553.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia	186801|Clostridia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
HGCANGJP_01671	1121115.AXVN01000003_gene1588	7.14e-194	538.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
HGCANGJP_01672	457412.RSAG_00606	5.4e-226	623.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
HGCANGJP_01673	1121115.AXVN01000003_gene1586	1.03e-172	483.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3Y1BD@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
HGCANGJP_01674	1121115.AXVN01000003_gene1585	6.15e-128	364.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3Y1PX@572511|Blautia	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HGCANGJP_01675	457412.RSAG_00603	1.3e-240	660.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia,3WH98@541000|Ruminococcaceae	186801|Clostridia	KT	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
HGCANGJP_01676	457412.RSAG_00602	0.0	967.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,3WJ03@541000|Ruminococcaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
HGCANGJP_01677	457412.RSAG_00601	8.72e-280	764.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1,Amidohydro_3
HGCANGJP_01678	457412.RSAG_00600	7.21e-236	647.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3WGAM@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
HGCANGJP_01679	457412.RSAG_00599	0.0	1177.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3WIA6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
HGCANGJP_01680	1121115.AXVN01000005_gene2281	7.85e-241	662.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
HGCANGJP_01681	1121115.AXVN01000005_gene2280	6.9e-166	463.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3XYM6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
HGCANGJP_01682	457412.RSAG_02988	2.94e-184	511.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3WK2R@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
HGCANGJP_01683	1121115.AXVN01000005_gene2278	3.76e-141	400.0	COG1207@1|root,COG1207@2|Bacteria,1UH92@1239|Firmicutes,25PYU@186801|Clostridia,3XYPK@572511|Blautia	186801|Clostridia	M	UDP-N-acetylglucosamine diphosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
HGCANGJP_01684	1121115.AXVN01000005_gene2277	0.0	1374.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3XYKF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
HGCANGJP_01685	1121115.AXVN01000005_gene2276	7.72e-178	495.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,3XZWD@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	fnt	-	-	ko:K02598	-	-	-	-	ko00000,ko02000	1.A.16.3	-	-	Form_Nir_trans
HGCANGJP_01686	1121115.AXVN01000005_gene2275	2.65e-249	684.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3XZ8H@572511|Blautia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
HGCANGJP_01687	1121115.AXVN01000005_gene2274	8e-49	155.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3Y0TN@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
HGCANGJP_01688	1121115.AXVN01000005_gene2273	1.58e-264	724.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3XZ7K@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HGCANGJP_01689	1121115.AXVN01000005_gene2272	0.0	911.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3XYGK@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
HGCANGJP_01690	457412.RSAG_02996	9.54e-153	428.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,3WGWP@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
HGCANGJP_01691	1121115.AXVN01000005_gene2270	4.09e-220	607.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,3XYYF@572511|Blautia	186801|Clostridia	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
HGCANGJP_01692	1121115.AXVN01000005_gene2269	3.41e-136	386.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,3XZVV@572511|Blautia	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
HGCANGJP_01693	457412.RSAG_02999	4.84e-234	645.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3WHJD@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
HGCANGJP_01694	457412.RSAG_03000	1.1e-179	500.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3WIAB@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
HGCANGJP_01695	1121115.AXVN01000005_gene2266	2.45e-176	493.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3XZ84@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
HGCANGJP_01696	457412.RSAG_03002	6.91e-299	815.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,3WH3A@541000|Ruminococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HGCANGJP_01697	457412.RSAG_03003	0.0	1041.0	29WVX@1|root,30IHI@2|Bacteria,1UPZS@1239|Firmicutes,257M6@186801|Clostridia,3WIT7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01698	1121115.AXVN01000005_gene2263	3.34e-305	836.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYK2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01699	1121115.AXVN01000005_gene2262	4.38e-161	452.0	2DPYM@1|root,333Z5@2|Bacteria,1VFMY@1239|Firmicutes,24SP4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01700	1121115.AXVN01000005_gene2261	3.38e-253	693.0	COG1835@1|root,COG1835@2|Bacteria,1VIE2@1239|Firmicutes,24SHJ@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HGCANGJP_01701	1121115.AXVN01000005_gene2260	1.71e-190	527.0	COG1278@1|root,COG1278@2|Bacteria,1URQI@1239|Firmicutes,259M3@186801|Clostridia,3Y0QB@572511|Blautia	186801|Clostridia	K	Domain of unknown function (DUF3825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3825
HGCANGJP_01702	1121115.AXVN01000005_gene2259	1.02e-291	796.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,3Y1FI@572511|Blautia	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
HGCANGJP_01703	1121115.AXVN01000005_gene2258	3.65e-220	606.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3XZAG@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
HGCANGJP_01704	1121115.AXVN01000005_gene2257	2.31e-261	714.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3XZ56@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
HGCANGJP_01705	1121115.AXVN01000005_gene2256	1.5e-231	636.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3XZI0@572511|Blautia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
HGCANGJP_01706	457412.RSAG_03013	0.0	1211.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,3WN2E@541000|Ruminococcaceae	186801|Clostridia	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
HGCANGJP_01707	457412.RSAG_03014	4.02e-237	652.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WIYW@541000|Ruminococcaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
HGCANGJP_01708	1121115.AXVN01000005_gene2253	3.67e-149	419.0	COG1102@1|root,COG1102@2|Bacteria,1V5TS@1239|Firmicutes,24HRW@186801|Clostridia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_01709	1121115.AXVN01000005_gene2252	3.96e-178	496.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,3Y0Y6@572511|Blautia	186801|Clostridia	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
HGCANGJP_01710	457412.RSAG_03018	5.45e-312	851.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3WHD3@541000|Ruminococcaceae	186801|Clostridia	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
HGCANGJP_01711	1121115.AXVN01000005_gene2250	1.67e-95	278.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
HGCANGJP_01712	1121115.AXVN01000005_gene2249	1.25e-241	664.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia,3Y17T@572511|Blautia	186801|Clostridia	E	Pfam:AHS2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
HGCANGJP_01713	457412.RSAG_03021	2.93e-177	493.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia,3WNN6@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:AHS1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
HGCANGJP_01714	457412.RSAG_03022	7.09e-258	710.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,248DM@186801|Clostridia,3WGJU@541000|Ruminococcaceae	186801|Clostridia	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
HGCANGJP_01715	397288.C806_01618	4.56e-78	233.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,27MSR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HGCANGJP_01716	1121115.AXVN01000158_gene1656	4.86e-206	570.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3XZ9A@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_01717	457412.RSAG_02315	7.69e-134	380.0	28PIW@1|root,2ZC8Q@2|Bacteria,1V1ZT@1239|Firmicutes,24FWM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
HGCANGJP_01718	1121115.AXVN01000158_gene1655	5.59e-213	598.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,3XYR2@572511|Blautia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HGCANGJP_01719	411459.RUMOBE_00356	0.0	999.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_01720	500632.CLONEX_03953	0.0	1032.0	COG1961@1|root,COG1961@2|Bacteria,1VRH6@1239|Firmicutes,24ZMB@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_01721	411459.RUMOBE_00359	2.42e-32	112.0	2CKK8@1|root,344MA@2|Bacteria,1W164@1239|Firmicutes,254GB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01722	411459.RUMOBE_00360	0.0	1463.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
HGCANGJP_01723	1408323.JQKK01000009_gene1234	0.000435	43.1	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27KKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HGCANGJP_01724	411459.RUMOBE_00362	0.0	1070.0	COG1132@1|root,COG1132@2|Bacteria,1TT2V@1239|Firmicutes,24AKS@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_01725	411459.RUMOBE_00363	4.39e-268	733.0	COG1404@1|root,COG1404@2|Bacteria,1VIFX@1239|Firmicutes,25BFS@186801|Clostridia	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HGCANGJP_01726	411459.RUMOBE_00364	0.0	1003.0	2F1TN@1|root,33UTQ@2|Bacteria,1VV6Q@1239|Firmicutes,24A9G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01729	411459.RUMOBE_00366	3.25e-251	689.0	2ACYN@1|root,32TJA@2|Bacteria,1VD19@1239|Firmicutes,24PI1@186801|Clostridia	186801|Clostridia	S	Peptide maturation system protein, TIGR04066 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01730	411459.RUMOBE_00367	0.0	948.0	COG0641@1|root,COG0641@2|Bacteria,1TT6S@1239|Firmicutes,248QW@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
HGCANGJP_01731	411459.RUMOBE_00368	2.3e-152	428.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3XZV2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_01732	411459.RUMOBE_00369	6.45e-209	578.0	28ITJ@1|root,2Z8SG@2|Bacteria,1V0TD@1239|Firmicutes,24AI9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01733	411459.RUMOBE_00371	2.48e-174	486.0	2C82F@1|root,32YEJ@2|Bacteria,1UPYJ@1239|Firmicutes,24FW9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01734	411459.RUMOBE_00372	2.65e-224	620.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia,3Y166@572511|Blautia	186801|Clostridia	-	-	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
HGCANGJP_01735	411459.RUMOBE_00373	2.93e-85	251.0	28ZZK@1|root,2ZMPX@2|Bacteria,1V41I@1239|Firmicutes,24RFQ@186801|Clostridia,3Y1MK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01736	411459.RUMOBE_00374	3.98e-169	472.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,3Y084@572511|Blautia	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HGCANGJP_01737	411459.RUMOBE_00375	1.35e-204	566.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3XZBX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HGCANGJP_01738	411459.RUMOBE_00376	8.07e-40	132.0	2E6BP@1|root,330ZG@2|Bacteria,1VEZW@1239|Firmicutes,24MZZ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
HGCANGJP_01739	500632.CLONEX_03971	0.0	1092.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,25EHI@186801|Clostridia	186801|Clostridia	S	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HGCANGJP_01740	411459.RUMOBE_00379	4.86e-157	440.0	28II2@1|root,2Z8J8@2|Bacteria,1UZV1@1239|Firmicutes,24FF4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01741	411459.RUMOBE_00380	4.69e-86	253.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,24IHH@186801|Clostridia,3XZWF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_01742	411459.RUMOBE_00381	2.97e-30	107.0	2CKK9@1|root,34AQN@2|Bacteria,1W083@1239|Firmicutes,253H1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01743	1121115.AXVN01000158_gene1655	6e-193	547.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,3XYR2@572511|Blautia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
HGCANGJP_01745	1408323.JQKK01000003_gene2624	9.39e-23	94.4	29UAT@1|root,30FM1@2|Bacteria,1UE7T@1239|Firmicutes,25J2Y@186801|Clostridia,27T5M@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
HGCANGJP_01746	1121115.AXVN01000131_gene734	5.74e-204	565.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,3XZUG@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_01747	457412.RSAG_02311	1.9e-229	630.0	COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,3WSRT@541000|Ruminococcaceae	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	dsvA	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr
HGCANGJP_01748	457412.RSAG_02310	0.0	1062.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3WGHR@541000|Ruminococcaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
HGCANGJP_01749	457412.RSAG_02307	1.13e-54	172.0	2BQ4H@1|root,32IYV@2|Bacteria,1US27@1239|Firmicutes,25A0K@186801|Clostridia,3WQZK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01750	457412.RSAG_02303	2.11e-175	490.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WG7F@541000|Ruminococcaceae	186801|Clostridia	P	Metal cation transporter, ZIP family	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
HGCANGJP_01751	457412.RSAG_02302	1.13e-89	263.0	COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,24ZZZ@186801|Clostridia	186801|Clostridia	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
HGCANGJP_01752	1121115.AXVN01000038_gene3335	1.35e-127	363.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,3Y025@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
HGCANGJP_01753	457412.RSAG_02294	2.46e-75	229.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01754	1121115.AXVN01000010_gene2746	4.03e-47	151.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HGCANGJP_01755	483218.BACPEC_00281	2.32e-125	362.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,268Z5@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_01756	1121115.AXVN01000010_gene2772	2.25e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,3Y04C@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_01757	1121115.AXVN01000010_gene2773	5.6e-81	239.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3Y05X@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
HGCANGJP_01758	457412.RSAG_02262	5.13e-87	256.0	COG1943@1|root,COG1943@2|Bacteria,1V5MU@1239|Firmicutes,24HFH@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
HGCANGJP_01759	457412.RSAG_02263	4.42e-271	742.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,24CV7@186801|Clostridia,3WR4V@541000|Ruminococcaceae	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
HGCANGJP_01760	1121115.AXVN01000010_gene2774	2.3e-213	591.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01761	1121115.AXVN01000010_gene2775	2.29e-88	259.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,3Y06A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
HGCANGJP_01762	1121115.AXVN01000010_gene2776	7.58e-187	521.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3XYMF@572511|Blautia	186801|Clostridia	P	COG COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
HGCANGJP_01763	457412.RSAG_01431	2.88e-190	530.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,3WGFX@541000|Ruminococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HGCANGJP_01764	1121115.AXVN01000010_gene2778	1.26e-192	537.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3XYWM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
HGCANGJP_01765	1121115.AXVN01000010_gene2779	4.13e-178	496.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3XYGV@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
HGCANGJP_01766	457412.RSAG_01428	1.05e-153	432.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3WIXN@541000|Ruminococcaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
HGCANGJP_01767	1121115.AXVN01000010_gene2781	0.0	941.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZMN@572511|Blautia	186801|Clostridia	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
HGCANGJP_01768	457412.RSAG_01421	0.0	1650.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_01769	1121115.AXVN01000010_gene2788	2.21e-133	377.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HGCANGJP_01770	1121115.AXVN01000010_gene2789	1.64e-123	353.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
HGCANGJP_01771	457412.RSAG_01418	0.0	932.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	atsB	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
HGCANGJP_01772	1121115.AXVN01000010_gene2791	0.0	1056.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3Y1DA@572511|Blautia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
HGCANGJP_01773	1121115.AXVN01000010_gene2792	0.0	914.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3Y10H@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
HGCANGJP_01774	411459.RUMOBE_03025	1.6e-213	593.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
HGCANGJP_01775	457412.RSAG_01414	0.0	949.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WH2F@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, ATPase component	araG_1	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
HGCANGJP_01776	1121115.AXVN01000010_gene2795	1.78e-224	622.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia,3Y10U@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	ytfT	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HGCANGJP_01777	1121115.AXVN01000010_gene2796	5.06e-205	572.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia,3Y1F9@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
HGCANGJP_01778	1235792.C808_04326	9.35e-191	536.0	COG1397@1|root,COG1397@2|Bacteria,1U2AQ@1239|Firmicutes,24KT9@186801|Clostridia	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HGCANGJP_01779	1274374.CBLK010000055_gene47	4.01e-82	256.0	COG1175@1|root,COG1175@2|Bacteria,1TSIQ@1239|Firmicutes,4HC0D@91061|Bacilli,26VDF@186822|Paenibacillaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_01780	97139.C824_03450	1.38e-98	297.0	COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,24AZD@186801|Clostridia,36FB4@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
HGCANGJP_01781	97139.C824_03451	1.96e-103	322.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia,36DXR@31979|Clostridiaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
HGCANGJP_01782	1033743.CAES01000099_gene2650	4.09e-35	134.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,4HM9S@91061|Bacilli,27672@186822|Paenibacillaceae	91061|Bacilli	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HGCANGJP_01783	1262449.CP6013_1543	1.39e-82	257.0	COG1082@1|root,COG1082@2|Bacteria,1TRCB@1239|Firmicutes,24HY3@186801|Clostridia,36J3X@31979|Clostridiaceae	186801|Clostridia	G	sugar phosphate isomerase epimerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
HGCANGJP_01784	592026.GCWU0000282_003077	3.8e-61	198.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia	186801|Clostridia	E	MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
HGCANGJP_01785	1235792.C808_04328	4.76e-64	207.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia	186801|Clostridia	K	UbiC transcription regulator-associated domain protein	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
HGCANGJP_01789	478749.BRYFOR_06660	4.63e-55	178.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_01790	622312.ROSEINA2194_03142	2e-144	418.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_01791	1235802.C823_03611	2.04e-62	198.0	2ENMS@1|root,33G93@2|Bacteria,1VMF6@1239|Firmicutes,24QEZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01793	411483.FAEPRAA2165_00220	2.81e-140	402.0	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia,3WSPR@541000|Ruminococcaceae	186801|Clostridia	D	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HGCANGJP_01794	411459.RUMOBE_03557	6.49e-30	115.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,3Y0YZ@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HGCANGJP_01795	1121115.AXVN01000041_gene2574	3.05e-129	370.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,24HHG@186801|Clostridia,3XYJI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yicG	-	-	-	-	-	-	-	-	-	-	-	UPF0126
HGCANGJP_01796	1121115.AXVN01000041_gene2581	0.0	1108.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3XYYP@572511|Blautia	186801|Clostridia	P	COG COG0004 Ammonia permease	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
HGCANGJP_01797	457412.RSAG_01359	0.0	1387.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
HGCANGJP_01798	457412.RSAG_01358	0.0	939.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
HGCANGJP_01799	1121115.AXVN01000041_gene2584	2.26e-46	149.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia,3Y0M0@572511|Blautia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
HGCANGJP_01800	457412.RSAG_01356	0.0	1082.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
HGCANGJP_01801	1121115.AXVN01000041_gene2586	0.0	2973.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3XZ2S@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
HGCANGJP_01802	1121115.AXVN01000041_gene2587	0.0	993.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3XZHX@572511|Blautia	186801|Clostridia	C	NADH-dependent glutamate synthase small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
HGCANGJP_01803	457412.RSAG_01351	5.42e-20	80.1	2C5R4@1|root,2ZP19@2|Bacteria,1W6F9@1239|Firmicutes,255YP@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_01804	457412.RSAG_01350	8.63e-190	528.0	COG0789@1|root,COG0789@2|Bacteria,1UZ91@1239|Firmicutes,249BQ@186801|Clostridia,3WS79@541000|Ruminococcaceae	186801|Clostridia	K	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,MerR_1,RDD
HGCANGJP_01805	1121115.AXVN01000041_gene2592	1.02e-163	458.0	COG1131@1|root,COG1131@2|Bacteria,1V4NG@1239|Firmicutes	1239|Firmicutes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_01806	457412.RSAG_01348	2.51e-262	721.0	2F0KS@1|root,33TPE@2|Bacteria,1VTU9@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01807	1121115.AXVN01000041_gene2593	3.09e-56	174.0	2CM8T@1|root,32SE0@2|Bacteria,1VBP1@1239|Firmicutes,24Q65@186801|Clostridia	186801|Clostridia	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
HGCANGJP_01808	1121115.AXVN01000041_gene2594	1.38e-82	244.0	COG1598@1|root,COG1598@2|Bacteria,1VAII@1239|Firmicutes,24I04@186801|Clostridia	186801|Clostridia	S	HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
HGCANGJP_01809	1121115.AXVN01000041_gene2595	0.0	893.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3XYYT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
HGCANGJP_01810	1121115.AXVN01000041_gene2596	2.66e-120	344.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,3Y020@572511|Blautia	186801|Clostridia	K	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
HGCANGJP_01811	1121115.AXVN01000041_gene2597	3e-156	451.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3XZ7F@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
HGCANGJP_01812	1121115.AXVN01000041_gene2600	0.0	950.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,3XYZ1@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
HGCANGJP_01813	1121115.AXVN01000041_gene2599	0.0	961.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,3XZNT@572511|Blautia	186801|Clostridia	H	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
HGCANGJP_01814	1121115.AXVN01000041_gene2598	3.23e-59	183.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,3Y0HE@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
HGCANGJP_01815	1121115.AXVN01000041_gene2597	6.06e-145	418.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3XZ7F@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
HGCANGJP_01816	1121115.AXVN01000041_gene2601	2.27e-196	549.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3XYT4@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HGCANGJP_01817	1121115.AXVN01000187_gene1813	1.97e-33	115.0	2EI8P@1|root,332BW@2|Bacteria,1VFSF@1239|Firmicutes,24RRY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01818	1121115.AXVN01000187_gene1812	3.12e-292	797.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia,3XZIJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
HGCANGJP_01819	1121115.AXVN01000001_gene1147	5.76e-146	410.0	COG0731@1|root,COG0731@2|Bacteria,1UJ6S@1239|Firmicutes,25EWY@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
HGCANGJP_01820	457412.RSAG_01274	6.07e-114	328.0	COG4720@1|root,COG4720@2|Bacteria,1V8B5@1239|Firmicutes,24J8T@186801|Clostridia,3WJ8C@541000|Ruminococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
HGCANGJP_01821	1121115.AXVN01000001_gene1149	4.53e-205	567.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,3XZZQ@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
HGCANGJP_01822	457412.RSAG_01276	1.67e-310	847.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WHQS@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
HGCANGJP_01823	1121115.AXVN01000001_gene1151	2.31e-147	415.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,3XZ03@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
HGCANGJP_01824	457412.RSAG_01278	0.0	973.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,3WHB7@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
HGCANGJP_01825	457412.RSAG_01279	7.42e-256	701.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
HGCANGJP_01826	457412.RSAG_01280	1.75e-227	627.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,3WGT1@541000|Ruminococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
HGCANGJP_01827	457412.RSAG_01281	0.0	940.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3WH17@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
HGCANGJP_01828	1121115.AXVN01000001_gene1156	0.0	1336.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3XYK0@572511|Blautia	186801|Clostridia	H	precorrin-6B methylase decarboxylase cbiT cbiE	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
HGCANGJP_01829	1121115.AXVN01000001_gene1157	2.31e-175	488.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3XZR9@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HGCANGJP_01830	1121115.AXVN01000001_gene1158	1.21e-265	728.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3XZ11@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
HGCANGJP_01831	457412.RSAG_01285	2.49e-182	507.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
HGCANGJP_01832	1121115.AXVN01000001_gene1160	2.28e-272	746.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3XYN5@572511|Blautia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
HGCANGJP_01833	457412.RSAG_01287	4.27e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WHZE@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01834	457412.RSAG_01288	8.91e-217	598.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
HGCANGJP_01835	457412.RSAG_01289	2.2e-174	487.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WHZV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
HGCANGJP_01836	457412.RSAG_01290	3.59e-284	777.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3WGXA@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
HGCANGJP_01837	457412.RSAG_01291	6.57e-136	384.0	COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,24JEE@186801|Clostridia,3WIXW@541000|Ruminococcaceae	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
HGCANGJP_01838	457412.RSAG_01292	2.14e-158	448.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,3WS4C@541000|Ruminococcaceae	186801|Clostridia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
HGCANGJP_01839	1121115.AXVN01000001_gene1167	1.03e-115	331.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3XZVQ@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
HGCANGJP_01840	1121115.AXVN01000001_gene1168	4.02e-76	231.0	COG3103@1|root,COG3103@2|Bacteria,1UHDJ@1239|Firmicutes,25Q4A@186801|Clostridia,3Y0IP@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
HGCANGJP_01841	457412.RSAG_01296	3.07e-240	660.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
HGCANGJP_01842	457412.RSAG_01297	7.36e-273	748.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HGCANGJP_01843	1121115.AXVN01000001_gene1171	2.72e-141	399.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3Y06N@572511|Blautia	186801|Clostridia	O	COG NOG13230 non supervised orthologous group	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
HGCANGJP_01844	1121115.AXVN01000001_gene1172	0.0	917.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,3XZ6S@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
HGCANGJP_01845	457412.RSAG_01300	1.07e-150	423.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,3WM7H@541000|Ruminococcaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
HGCANGJP_01846	457412.RSAG_01301	1.4e-298	815.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia,3WS78@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_01847	457412.RSAG_01302	4.65e-168	469.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3WJ2Q@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_01848	1121115.AXVN01000001_gene1176	5.14e-42	137.0	2FI33@1|root,349VV@2|Bacteria,1VYV4@1239|Firmicutes,253ZQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01849	457412.RSAG_01304	2.23e-119	341.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01850	1121115.AXVN01000170_gene502	9.63e-248	679.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
HGCANGJP_01851	1121115.AXVN01000170_gene503	5.14e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3Y022@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
HGCANGJP_01852	457412.RSAG_04656	4.65e-256	701.0	COG2365@1|root,COG2365@2|Bacteria,1V639@1239|Firmicutes,25CGQ@186801|Clostridia	186801|Clostridia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
HGCANGJP_01853	457412.RSAG_00418	9.24e-213	587.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3WGYB@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
HGCANGJP_01854	457412.RSAG_00417	0.0	2097.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HGCANGJP_01855	1121115.AXVN01000004_gene1984	0.0	910.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	uidB_2	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
HGCANGJP_01856	1121115.AXVN01000004_gene1983	6.37e-189	525.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia,3Y2AU@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_01857	1121115.AXVN01000004_gene1982	5.09e-203	561.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
HGCANGJP_01858	457412.RSAG_00413	0.0	1206.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WHK3@541000|Ruminococcaceae	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
HGCANGJP_01859	1121115.AXVN01000004_gene1980	0.0	1114.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XYGZ@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_01860	1121115.AXVN01000004_gene1979	0.0	1108.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTP@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_01861	1121115.AXVN01000004_gene1978	1.42e-309	843.0	COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,3Y0V9@572511|Blautia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
HGCANGJP_01862	1121115.AXVN01000004_gene1977	0.0	1087.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,3Y04S@572511|Blautia	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC_1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
HGCANGJP_01863	1121115.AXVN01000004_gene1976	0.0	895.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HGCANGJP_01864	1121115.AXVN01000004_gene1975	3.58e-209	579.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3XZ0R@572511|Blautia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HGCANGJP_01865	1121115.AXVN01000004_gene1974	0.0	1184.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3XZB2@572511|Blautia	186801|Clostridia	GT	Psort location CytoplasmicMembrane, score 10.00	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
HGCANGJP_01866	1121115.AXVN01000004_gene1973	3.46e-54	169.0	COG1925@1|root,COG1925@2|Bacteria,1VE7N@1239|Firmicutes,24Q2D@186801|Clostridia,3Y0JB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	ptsH	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
HGCANGJP_01867	1121115.AXVN01000004_gene1972	1.32e-167	469.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3XYWN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
HGCANGJP_01868	457412.RSAG_00403	6.5e-268	734.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3WH9B@541000|Ruminococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
HGCANGJP_01869	1121115.AXVN01000004_gene1969	0.0	1986.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,3XZKX@572511|Blautia	186801|Clostridia	L	Psort location	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
HGCANGJP_01870	1121115.AXVN01000004_gene1968	3.14e-132	374.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3Y04A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
HGCANGJP_01871	1121115.AXVN01000004_gene1967	2.14e-100	290.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3Y024@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
HGCANGJP_01872	457412.RSAG_00399	1.75e-229	630.0	COG2207@1|root,COG2207@2|Bacteria,1UZED@1239|Firmicutes,2490G@186801|Clostridia,3WKBN@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
HGCANGJP_01873	1121115.AXVN01000004_gene1965	5.44e-315	859.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZ7G@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01874	457412.RSAG_00397	3.71e-147	414.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,3WJ44@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	-	-	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
HGCANGJP_01875	1121115.AXVN01000004_gene1962	1.7e-60	186.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
HGCANGJP_01876	457412.RSAG_00395	2.96e-91	267.0	COG2172@1|root,COG2172@2|Bacteria,1VAPM@1239|Firmicutes,24J9J@186801|Clostridia,3WKBK@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
HGCANGJP_01877	1121115.AXVN01000004_gene1960	6.85e-266	733.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3Y16V@572511|Blautia	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
HGCANGJP_01878	457412.RSAG_00393	9.23e-270	737.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01879	1121115.AXVN01000004_gene1958	5.16e-186	518.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,257P6@186801|Clostridia,3Y1PM@572511|Blautia	186801|Clostridia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
HGCANGJP_01880	457412.RSAG_00391	2.29e-178	497.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	pyrL	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
HGCANGJP_01881	1121115.AXVN01000004_gene1956	5.19e-169	473.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_01882	1121115.AXVN01000004_gene1955	1.41e-264	724.0	COG1835@1|root,COG1835@2|Bacteria,1U1IX@1239|Firmicutes,25J4S@186801|Clostridia,3Y0VP@572511|Blautia	186801|Clostridia	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
HGCANGJP_01883	1121115.AXVN01000004_gene1954	3.59e-268	734.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,3Y04U@572511|Blautia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
HGCANGJP_01884	1121115.AXVN01000004_gene1953	6.7e-271	738.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
HGCANGJP_01885	1121115.AXVN01000004_gene1952	6.94e-316	858.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3Y1R0@572511|Blautia	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
HGCANGJP_01886	1121115.AXVN01000004_gene1951	2.94e-97	282.0	COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,24HAQ@186801|Clostridia	186801|Clostridia	IM	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
HGCANGJP_01887	457412.RSAG_00384	1.15e-300	820.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3WR0Q@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
HGCANGJP_01888	1121115.AXVN01000004_gene1949	0.0	1958.0	COG0438@1|root,COG1887@1|root,COG0438@2|Bacteria,COG1887@2|Bacteria,1TSEW@1239|Firmicutes,25KH4@186801|Clostridia,3Y05H@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
HGCANGJP_01889	1121115.AXVN01000004_gene1948	3.37e-176	492.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3XZ0B@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HGCANGJP_01890	1121115.AXVN01000004_gene1947	7.57e-61	186.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,25P5S@186801|Clostridia,3Y0IV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PRC
HGCANGJP_01891	1121115.AXVN01000004_gene1946	4.38e-102	295.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3XZYK@572511|Blautia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
HGCANGJP_01892	1121115.AXVN01000004_gene1945	0.0	878.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
HGCANGJP_01893	1121115.AXVN01000004_gene1944	0.0	899.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XYZV@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HGCANGJP_01894	1121115.AXVN01000004_gene1943	7.3e-121	344.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3XZXE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
HGCANGJP_01895	1121115.AXVN01000004_gene1942	1.7e-118	339.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3Y095@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
HGCANGJP_01896	1121115.AXVN01000004_gene1941	3.66e-132	374.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
HGCANGJP_01897	1121115.AXVN01000004_gene1940	4.13e-231	637.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,3Y032@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
HGCANGJP_01899	1121115.AXVN01000004_gene1939	8.87e-162	453.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3XZ4H@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_01900	457412.RSAG_00367	0.0	1004.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WSQQ@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_01901	457412.RSAG_00365	1.58e-153	431.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HGCANGJP_01902	1121115.AXVN01000004_gene1936	6.86e-177	493.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3XZ31@572511|Blautia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
HGCANGJP_01903	1121115.AXVN01000004_gene1935	4.9e-172	478.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,3XYSN@572511|Blautia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
HGCANGJP_01904	1121115.AXVN01000004_gene1934	0.0	1010.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3XZ3N@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
HGCANGJP_01905	1121115.AXVN01000004_gene1933	0.0	2796.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3XYXK@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
HGCANGJP_01906	1121115.AXVN01000004_gene1932	2.08e-287	783.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3XZ2I@572511|Blautia	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
HGCANGJP_01907	1121115.AXVN01000004_gene1930	8.14e-63	192.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia	186801|Clostridia	U	COG COG1862 Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
HGCANGJP_01908	1121115.AXVN01000004_gene1929	4.82e-254	697.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3XZ5D@572511|Blautia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
HGCANGJP_01909	1121115.AXVN01000004_gene1928	0.0	1098.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3XYR1@572511|Blautia	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
HGCANGJP_01910	457412.RSAG_00355	0.0	1106.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HGCANGJP_01911	1121115.AXVN01000004_gene1926	1.4e-262	719.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3XZDW@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
HGCANGJP_01912	457412.RSAG_00353	4.65e-277	758.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
HGCANGJP_01913	1121115.AXVN01000009_gene1456	3.3e-234	644.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
HGCANGJP_01914	457412.RSAG_00349	0.0	1509.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HGCANGJP_01916	1121115.AXVN01000020_gene79	0.0	895.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
HGCANGJP_01917	1121115.AXVN01000009_gene1459	5.84e-274	751.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XZ16@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
HGCANGJP_01918	1121115.AXVN01000009_gene1460	4.66e-197	547.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,24F3Z@186801|Clostridia,3XZMZ@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
HGCANGJP_01919	1121115.AXVN01000009_gene1461	4.4e-171	479.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,3XZ3R@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iHN637.CLJU_RS10670	BPD_transp_1
HGCANGJP_01920	457412.RSAG_00345	7.08e-250	686.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
HGCANGJP_01921	1121115.AXVN01000009_gene1463	7.09e-184	512.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3XYI0@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
HGCANGJP_01922	457412.RSAG_00343	0.0	1142.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WHCV@541000|Ruminococcaceae	186801|Clostridia	P	Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
HGCANGJP_01923	1121115.AXVN01000009_gene1465	6.04e-249	683.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3XZJT@572511|Blautia	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
HGCANGJP_01924	1121115.AXVN01000009_gene1466	0.0	1055.0	COG1080@1|root,COG1080@2|Bacteria,1VRHN@1239|Firmicutes,24YXY@186801|Clostridia,3XZB5@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
HGCANGJP_01925	1121115.AXVN01000009_gene1467	1.47e-265	728.0	COG1146@1|root,COG2006@1|root,COG1146@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,3XZST@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
HGCANGJP_01926	1121115.AXVN01000009_gene1468	2e-201	559.0	COG0646@1|root,COG0646@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3XZSY@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
HGCANGJP_01927	1121115.AXVN01000009_gene1469	1.13e-224	617.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3XZNJ@572511|Blautia	186801|Clostridia	G	COG COG2017 Galactose mutarotase and related enzymes	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
HGCANGJP_01928	1121115.AXVN01000009_gene1470	1.11e-302	825.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XZA1@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
HGCANGJP_01929	1121115.AXVN01000009_gene1471	0.0	1743.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia	186801|Clostridia	G	Phosphoenolpyruvate synthase pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
HGCANGJP_01930	457412.RSAG_00274	4.31e-177	493.0	COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,24IY3@186801|Clostridia,3WKX0@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	cas6	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
HGCANGJP_01931	457412.RSAG_00273	0.0	1570.0	COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,24BI3@186801|Clostridia,3WNZQ@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated protein, Csm1 family	csm1	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
HGCANGJP_01932	457412.RSAG_00272	6.81e-86	253.0	COG1421@1|root,COG1421@2|Bacteria,1VGBY@1239|Firmicutes,24R4K@186801|Clostridia,3WQNQ@541000|Ruminococcaceae	186801|Clostridia	L	Pfam:DUF310	csm2	-	-	ko:K19138	-	-	-	-	ko00000,ko02048	-	-	-	Csm2_III-A
HGCANGJP_01933	457412.RSAG_00271	8.32e-149	419.0	COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,24IQD@186801|Clostridia,3WPKV@541000|Ruminococcaceae	186801|Clostridia	L	RAMP superfamily	csm3	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
HGCANGJP_01934	457412.RSAG_00270	5.42e-226	622.0	COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes,24IT6@186801|Clostridia,3WPNR@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
HGCANGJP_01935	457412.RSAG_00269	2.43e-265	726.0	COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes,24IAY@186801|Clostridia,3WPY4@541000|Ruminococcaceae	186801|Clostridia	L	RAMP superfamily	csm5	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
HGCANGJP_01936	457412.RSAG_00268	8.22e-246	674.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,3WG8Q@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
HGCANGJP_01937	457412.RSAG_04730	9.69e-72	216.0	COG1343@1|root,COG1343@2|Bacteria,1VFRC@1239|Firmicutes,24R2N@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
HGCANGJP_01938	457412.RSAG_00265	0.0	869.0	28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes,24F8S@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein (Cas_Csm6)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Csm6
HGCANGJP_01940	457412.RSAG_00263	1.98e-163	457.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,3WJDW@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
HGCANGJP_01941	457412.RSAG_00262	3.96e-253	694.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WG95@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
HGCANGJP_01942	457412.RSAG_00261	0.0	986.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,3WHZ9@541000|Ruminococcaceae	186801|Clostridia	L	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
HGCANGJP_01943	545694.TREPR_0820	9.03e-152	439.0	COG0732@1|root,COG0732@2|Bacteria,2J8T9@203691|Spirochaetes	203691|Spirochaetes	V	Type I R-M system	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
HGCANGJP_01944	483218.BACPEC_01348	4.78e-134	384.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,26AXC@186813|unclassified Clostridiales	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
HGCANGJP_01945	457412.RSAG_00258	2.15e-104	301.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V1UV@1239|Firmicutes,25CWU@186801|Clostridia,3WS04@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01946	457412.RSAG_00256	0.0	2182.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia,3WGBZ@541000|Ruminococcaceae	186801|Clostridia	L	EcoEI R protein C-terminal	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
HGCANGJP_01947	457412.RSAG_00255	1.54e-142	401.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia,3WI1J@541000|Ruminococcaceae	186801|Clostridia	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
HGCANGJP_01948	1121115.AXVN01000017_gene270	3.16e-158	443.0	COG1787@1|root,COG1787@2|Bacteria,1TTX3@1239|Firmicutes,25P6F@186801|Clostridia,3Y1RR@572511|Blautia	186801|Clostridia	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat
HGCANGJP_01949	457412.RSAG_00253	1e-166	467.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3WIP0@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HGCANGJP_01950	457412.RSAG_00252	0.0	925.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3WHMF@541000|Ruminococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase	ywdH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
HGCANGJP_01951	457412.RSAG_00251	6.07e-292	797.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,3WJCU@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
HGCANGJP_01952	1121115.AXVN01000017_gene266	3.99e-166	464.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3Y11K@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_01953	1121115.AXVN01000017_gene265	0.0	1510.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,3Y19B@572511|Blautia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HGCANGJP_01954	1121115.AXVN01000017_gene264	5.86e-70	214.0	2BBFY@1|root,324Z7@2|Bacteria,1UR44@1239|Firmicutes,258XU@186801|Clostridia,3Y266@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01955	457412.RSAG_00247	3.61e-316	863.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_01956	1121115.AXVN01000017_gene262	3.15e-126	359.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3Y0A5@572511|Blautia	186801|Clostridia	I	COG COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
HGCANGJP_01957	1121115.AXVN01000017_gene261	5.19e-277	756.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,3XZNX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
HGCANGJP_01958	1121115.AXVN01000018_gene19	7.39e-53	168.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes,250D1@186801|Clostridia,3Y0U5@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_01959	457412.RSAG_01649	8.68e-129	365.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
HGCANGJP_01960	457412.RSAG_01648	7.82e-97	281.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3WKYJ@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
HGCANGJP_01961	1232446.BAIE02000077_gene709	6.76e-40	136.0	2DMQ8@1|root,32SZ9@2|Bacteria,1VD1R@1239|Firmicutes,24MPF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
HGCANGJP_01962	1232446.BAIE02000077_gene710	3.63e-42	143.0	29VD9@1|root,30XVA@2|Bacteria,1V5XW@1239|Firmicutes,24IBP@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
HGCANGJP_01963	1121115.AXVN01000018_gene36	0.0	1318.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3XYH1@572511|Blautia	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
HGCANGJP_01964	1121115.AXVN01000018_gene37	1.44e-109	315.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,3Y01J@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
HGCANGJP_01965	457412.RSAG_01644	1.95e-109	315.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WHT9@541000|Ruminococcaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
HGCANGJP_01966	457412.RSAG_01643	7.41e-102	294.0	COG2258@1|root,COG2258@2|Bacteria,1UIYW@1239|Firmicutes,25FCC@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
HGCANGJP_01967	1121115.AXVN01000018_gene40	9.39e-183	508.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3XZFC@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
HGCANGJP_01968	457412.RSAG_01641	0.0	908.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3WIMU@541000|Ruminococcaceae	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
HGCANGJP_01969	1121115.AXVN01000018_gene42	3.05e-96	281.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,3Y09U@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
HGCANGJP_01970	1121115.AXVN01000018_gene43	8.17e-266	728.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
HGCANGJP_01971	457412.RSAG_01638	3.14e-254	697.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
HGCANGJP_01972	1121115.AXVN01000018_gene45	2.6e-231	636.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3Y1G9@572511|Blautia	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
HGCANGJP_01973	1121115.AXVN01000018_gene46	0.0	1517.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
HGCANGJP_01974	1121115.AXVN01000018_gene47	5.88e-258	709.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
HGCANGJP_01975	1121115.AXVN01000018_gene48	6.69e-135	382.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3Y15Q@572511|Blautia	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
HGCANGJP_01976	457412.RSAG_01633	3.1e-137	388.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3WI1I@541000|Ruminococcaceae	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
HGCANGJP_01977	1121115.AXVN01000018_gene50	1.78e-145	409.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
HGCANGJP_01978	457412.RSAG_01630	0.0	1599.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WHET@541000|Ruminococcaceae	186801|Clostridia	P	Calcium-translocating P-type ATPase, PMCA-type	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
HGCANGJP_01979	1121115.AXVN01000018_gene52	3.28e-173	484.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,3Y1I1@572511|Blautia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
HGCANGJP_01980	1235799.C818_01134	2.38e-127	366.0	COG2013@1|root,COG2013@2|Bacteria,1TSVH@1239|Firmicutes,24DQR@186801|Clostridia,27JVP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
HGCANGJP_01981	397291.C804_02849	6.77e-77	241.0	COG2310@1|root,COG2310@2|Bacteria,1V26C@1239|Firmicutes,24GMA@186801|Clostridia,27N1D@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	-	-	-	-	-	-	-	-	-	-	-	-	TerD
HGCANGJP_01982	1121115.AXVN01000018_gene53	0.0	1154.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,3XYKE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
HGCANGJP_01983	457412.RSAG_01628	3.15e-145	412.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3WRJN@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
HGCANGJP_01984	1121115.AXVN01000018_gene55	3.03e-134	381.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3XYVE@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
HGCANGJP_01985	1121115.AXVN01000018_gene56	0.0	913.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
HGCANGJP_01986	1121115.AXVN01000018_gene57	0.0	1170.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3XYVX@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
HGCANGJP_01987	1121115.AXVN01000018_gene58	2.95e-127	363.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,3Y0B1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
HGCANGJP_01988	1121115.AXVN01000018_gene59	5.62e-69	208.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3Y07R@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
HGCANGJP_01989	1121115.AXVN01000018_gene60	1.37e-84	251.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,3Y0BA@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
HGCANGJP_01990	1121115.AXVN01000018_gene61	0.0	1263.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
HGCANGJP_01991	457412.RSAG_01620	4.29e-255	699.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,3WGJ9@541000|Ruminococcaceae	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
HGCANGJP_01992	1121115.AXVN01000076_gene2617	2.59e-96	280.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3Y0J7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
HGCANGJP_01993	1121115.AXVN01000076_gene2618	2.62e-121	346.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3Y0KM@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HGCANGJP_01994	1121115.AXVN01000076_gene2619	4.24e-290	791.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia,3XZQQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
HGCANGJP_01995	1121115.AXVN01000076_gene2620	2.62e-197	546.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,3Y059@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HGCANGJP_01996	1121115.AXVN01000076_gene2621	3.57e-261	720.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,3Y03A@572511|Blautia	186801|Clostridia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
HGCANGJP_01997	1121115.AXVN01000076_gene2622	0.0	2147.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3XZME@572511|Blautia	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
HGCANGJP_01998	1121115.AXVN01000076_gene2623	1.32e-138	391.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3XYSI@572511|Blautia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
HGCANGJP_01999	457412.RSAG_03114	9.1e-235	645.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3WGKW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
HGCANGJP_02000	1121115.AXVN01000076_gene2625	7.37e-209	585.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3XYNY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
HGCANGJP_02001	457412.RSAG_03117	6.13e-48	153.0	2E6AD@1|root,330Y9@2|Bacteria,1VFG8@1239|Firmicutes,24RI6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02002	457412.RSAG_03118	0.0	1323.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
HGCANGJP_02003	457412.RSAG_03119	2.66e-269	743.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24MJ1@186801|Clostridia,3WRJS@541000|Ruminococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CW_binding_1,Cu_amine_oxidN1,DUF3298,Polysacc_deac_1,SH3_3
HGCANGJP_02004	1121115.AXVN01000076_gene2630	3.6e-271	746.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3Y00S@572511|Blautia	186801|Clostridia	M	COG COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
HGCANGJP_02005	1121115.AXVN01000076_gene2631	0.0	920.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3XZA7@572511|Blautia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HGCANGJP_02006	457412.RSAG_03122	0.0	1008.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
HGCANGJP_02007	1121115.AXVN01000091_gene2603	7.73e-72	219.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,3Y02Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02008	1121115.AXVN01000091_gene2604	5.7e-105	303.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,3Y0D5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
HGCANGJP_02009	1121115.AXVN01000091_gene2605	2.61e-196	544.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3XZR8@572511|Blautia	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
HGCANGJP_02010	1121115.AXVN01000091_gene2606	4.25e-50	159.0	2C5NI@1|root,33W5Y@2|Bacteria,1VWK5@1239|Firmicutes,2519Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02011	1121115.AXVN01000091_gene2607	0.0	1108.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25FHY@186801|Clostridia,3XZUD@572511|Blautia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
HGCANGJP_02012	457412.RSAG_03128	0.0	941.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3WHDF@541000|Ruminococcaceae	186801|Clostridia	EG	spore germination protein	gerA	-	-	ko:K06295,ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
HGCANGJP_02013	1121115.AXVN01000091_gene2609	4.75e-157	442.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3XZAU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HGCANGJP_02014	1121115.AXVN01000091_gene2610	1.11e-202	561.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3XZ86@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
HGCANGJP_02015	457412.RSAG_03131	0.0	999.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHGK@541000|Ruminococcaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
HGCANGJP_02016	1121115.AXVN01000091_gene2612	3.16e-93	272.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,3Y0BV@572511|Blautia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
HGCANGJP_02017	457412.RSAG_03133	1.62e-173	484.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WI78@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
HGCANGJP_02018	1121115.AXVN01000091_gene2614	0.0	984.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,3Y0NN@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_02019	1121115.AXVN01000091_gene2615	4.27e-313	852.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24A83@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
HGCANGJP_02020	457412.RSAG_03136	8.03e-223	615.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24FIE@186801|Clostridia,3WRZY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
HGCANGJP_02021	457412.RSAG_03170	0.0	1271.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3WH32@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
HGCANGJP_02022	1280698.AUJS01000020_gene1386	1.56e-51	163.0	2EBZC@1|root,335YN@2|Bacteria,1V8B8@1239|Firmicutes,24TTD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02023	1280698.AUJS01000020_gene1387	2.54e-46	149.0	28N4M@1|root,2ZBA1@2|Bacteria,1V0M7@1239|Firmicutes,24FM3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348,Tn916-Xis
HGCANGJP_02024	1280698.AUJS01000020_gene1388	1.52e-79	237.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia,27VRF@189330|Dorea	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_02025	1280698.AUJS01000020_gene1389	3.9e-34	117.0	2FGU8@1|root,348PJ@2|Bacteria,1W0KZ@1239|Firmicutes,24QZ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02026	1256908.HMPREF0373_03437	2.14e-47	153.0	2EJ89@1|root,33CZF@2|Bacteria,1VNWZ@1239|Firmicutes,24RJS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02027	518637.EUBIFOR_00788	4.03e-85	251.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes	1239|Firmicutes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
HGCANGJP_02028	742765.HMPREF9457_02920	1.19e-41	136.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,HTH_26,HTH_3
HGCANGJP_02029	1410624.JNKK01000001_gene628	0.0	1356.0	COG1002@1|root,COG1002@2|Bacteria,1TRZH@1239|Firmicutes,249I6@186801|Clostridia	186801|Clostridia	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
HGCANGJP_02030	1235790.C805_03488	4.36e-106	314.0	2B7B4@1|root,320E7@2|Bacteria,1V8P5@1239|Firmicutes,24NNJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02031	1235790.C805_03487	1.39e-140	411.0	COG0542@1|root,COG0542@2|Bacteria,1UZ7G@1239|Firmicutes,24C8B@186801|Clostridia,25YCY@186806|Eubacteriaceae	186801|Clostridia	O	Torsin	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2
HGCANGJP_02032	1195236.CTER_2626	2.65e-237	691.0	COG4694@1|root,COG4694@2|Bacteria,1TQ19@1239|Firmicutes,25B75@186801|Clostridia	186801|Clostridia	K	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
HGCANGJP_02033	518637.EUBIFOR_00775	3.18e-61	192.0	2F3XK@1|root,33WPP@2|Bacteria,1VWC7@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
HGCANGJP_02034	1280698.AUJS01000020_gene1401	0.0	1016.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HGCANGJP_02035	1280698.AUJS01000020_gene1402	0.0	1172.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia,27VNS@189330|Dorea	186801|Clostridia	L	COG NOG14428 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
HGCANGJP_02036	742765.HMPREF9457_01864	1.5e-64	197.0	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24JNU@186801|Clostridia	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
HGCANGJP_02037	471875.RUMLAC_00031	3.78e-74	222.0	COG3668@1|root,COG3668@2|Bacteria,1VD9X@1239|Firmicutes,24I2T@186801|Clostridia,3WKSU@541000|Ruminococcaceae	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
HGCANGJP_02038	1280698.AUJS01000020_gene1405	6.02e-14	65.5	2E3CH@1|root,32YBT@2|Bacteria,1VHJT@1239|Firmicutes,24RED@186801|Clostridia,27X7K@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02039	457412.RSAG_03169	0.0	1035.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,3WJCS@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
HGCANGJP_02040	1121115.AXVN01000055_gene1909	1.08e-243	669.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HGCANGJP_02041	1121115.AXVN01000055_gene1910	1.88e-220	607.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3Y14P@572511|Blautia	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
HGCANGJP_02042	1121115.AXVN01000055_gene1911	2.25e-239	658.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZP5@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HGCANGJP_02043	1121115.AXVN01000055_gene1912	1.02e-204	567.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZFZ@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
HGCANGJP_02044	1121115.AXVN01000055_gene1913	0.0	1112.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HGCANGJP_02045	1121115.AXVN01000055_gene1914	2.57e-52	164.0	2CDIT@1|root,338T3@2|Bacteria,1VJ1M@1239|Firmicutes,24SF4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HGCANGJP_02046	1121115.AXVN01000055_gene1915	1.52e-264	725.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3XYVJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
HGCANGJP_02047	1121115.AXVN01000055_gene1916	3.45e-240	659.0	COG5018@1|root,COG5018@2|Bacteria,1TQJZ@1239|Firmicutes,24845@186801|Clostridia,3XYID@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
HGCANGJP_02048	457412.RSAG_03160	1.45e-299	816.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HGCANGJP_02049	457412.RSAG_03158	0.0	2168.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
HGCANGJP_02050	457412.RSAG_03157	0.0	1642.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WHEI@541000|Ruminococcaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HGCANGJP_02051	457412.RSAG_04645	0.0	1042.0	COG5263@1|root,COG5263@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02052	1121115.AXVN01000024_gene312	1.88e-96	281.0	COG3238@1|root,COG3238@2|Bacteria,1V6J0@1239|Firmicutes,24JM9@186801|Clostridia,3Y03G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
HGCANGJP_02053	457412.RSAG_02177	1.32e-158	449.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WM12@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
HGCANGJP_02054	457412.RSAG_02176	9.41e-164	458.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3WIDV@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_02055	1121115.AXVN01000024_gene315	3.66e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
HGCANGJP_02056	457412.RSAG_02173	0.0	1220.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
HGCANGJP_02057	457412.RSAG_02172	0.0	1860.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,3WRQH@541000|Ruminococcaceae	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
HGCANGJP_02058	457412.RSAG_02171	0.0	1128.0	COG2221@1|root,COG4624@1|root,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24YQ5@186801|Clostridia,3WGXS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,PAS
HGCANGJP_02059	457412.RSAG_02170	1.81e-292	798.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,3WGNY@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
HGCANGJP_02060	457412.RSAG_02169	2.57e-103	298.0	COG2258@1|root,COG2258@2|Bacteria,1W5YX@1239|Firmicutes,255UB@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02061	1121115.AXVN01000022_gene1765	2.74e-304	829.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3Y0HF@572511|Blautia	186801|Clostridia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
HGCANGJP_02062	457412.RSAG_02167	1.25e-118	339.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,3WKCP@541000|Ruminococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
HGCANGJP_02063	457412.RSAG_02166	7.22e-198	548.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia,3WPB6@541000|Ruminococcaceae	186801|Clostridia	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
HGCANGJP_02064	457412.RSAG_02165	6.95e-238	653.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WHWT@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
HGCANGJP_02065	1121115.AXVN01000022_gene1761	4.91e-148	417.0	COG0746@1|root,COG0746@2|Bacteria,1UQ1Y@1239|Firmicutes,257PR@186801|Clostridia,3Y0VI@572511|Blautia	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
HGCANGJP_02066	457412.RSAG_02162	4.35e-143	404.0	2CKNK@1|root,306D0@2|Bacteria,1TZJW@1239|Firmicutes,2513T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02067	1121115.AXVN01000022_gene1759	3.75e-114	332.0	2F19F@1|root,33UAG@2|Bacteria,1VUX8@1239|Firmicutes,250KD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02068	1121115.AXVN01000022_gene1758	6.05e-69	208.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,3Y0R2@572511|Blautia	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
HGCANGJP_02069	1121115.AXVN01000022_gene1757	1.22e-272	750.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia	186801|Clostridia	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,RicinB_lectin_2
HGCANGJP_02071	1121115.AXVN01000022_gene1756	0.0	944.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XYXC@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_02072	457412.RSAG_02157	1.53e-215	596.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,3WJJR@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
HGCANGJP_02073	457412.RSAG_02156	0.0	1496.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WH2S@541000|Ruminococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
HGCANGJP_02074	1121115.AXVN01000022_gene1753	2.91e-316	860.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3XZEH@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 9.36	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HGCANGJP_02075	1121115.AXVN01000022_gene1752	3.14e-193	537.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3XZ2V@572511|Blautia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
HGCANGJP_02076	457412.RSAG_02153	2.75e-116	334.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3WJC2@541000|Ruminococcaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
HGCANGJP_02077	457412.RSAG_02152	1.18e-224	618.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
HGCANGJP_02078	1121115.AXVN01000022_gene1749	2.2e-227	627.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3XZ4T@572511|Blautia	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
HGCANGJP_02079	457412.RSAG_02150	6.44e-18	78.2	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
HGCANGJP_02080	1121115.AXVN01000022_gene1747	7.81e-209	578.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3XYQQ@572511|Blautia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
HGCANGJP_02081	1121115.AXVN01000022_gene1746	6.04e-262	724.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3XZD8@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
HGCANGJP_02082	457412.RSAG_01736	0.0	1133.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
HGCANGJP_02083	1121115.AXVN01000042_gene3008	2.69e-46	153.0	2F1AC@1|root,33UBB@2|Bacteria,1VUR2@1239|Firmicutes,2503K@186801|Clostridia,3Y24T@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02084	457412.RSAG_01734	5.75e-135	382.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
HGCANGJP_02085	1121115.AXVN01000042_gene3010	1.11e-162	454.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,3XZXU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
HGCANGJP_02086	1121115.AXVN01000042_gene3011	9.4e-192	532.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3XZTP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HGCANGJP_02087	457412.RSAG_01731	2.36e-51	162.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,3WKYT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02088	457412.RSAG_01730	0.0	1480.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,CHU_C,DUF11,IgGFc_binding,LTD,NPCBM_assoc,Peptidase_M11,SprB
HGCANGJP_02089	1121115.AXVN01000042_gene3014	0.0	1360.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3XZ94@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
HGCANGJP_02090	1121115.AXVN01000042_gene3015	7.42e-75	223.0	COG0745@1|root,COG0745@2|Bacteria,1UK3F@1239|Firmicutes,25FI6@186801|Clostridia,3Y0KY@572511|Blautia	186801|Clostridia	KT	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
HGCANGJP_02091	1121115.AXVN01000042_gene3016	4.58e-119	340.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,3Y05S@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02092	1121115.AXVN01000042_gene3017	2.51e-197	547.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3XYU8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HGCANGJP_02093	1121115.AXVN01000042_gene3018	7.64e-61	192.0	2DUBB@1|root,33PT0@2|Bacteria,1VSM4@1239|Firmicutes,24YVT@186801|Clostridia,3Y0NE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02094	1121115.AXVN01000042_gene3019	1.04e-41	136.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,3Y0CS@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
HGCANGJP_02095	1121115.AXVN01000042_gene3020	0.0	864.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3XYP9@572511|Blautia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
HGCANGJP_02096	1121115.AXVN01000042_gene3021	4.46e-226	622.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3XZ6C@572511|Blautia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
HGCANGJP_02097	1121115.AXVN01000042_gene3022	4.17e-192	532.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3XZA9@572511|Blautia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
HGCANGJP_02098	457412.RSAG_01720	2.17e-213	589.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3WGC5@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
HGCANGJP_02099	1121115.AXVN01000042_gene3024	2.7e-161	451.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3XYW9@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
HGCANGJP_02100	1121115.AXVN01000042_gene3025	6.09e-24	90.9	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,3Y0RQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02101	457412.RSAG_01717	3.03e-106	306.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,3WK49@541000|Ruminococcaceae	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HGCANGJP_02102	1121115.AXVN01000042_gene3027	4.05e-64	196.0	2EENY@1|root,338GS@2|Bacteria,1VJM1@1239|Firmicutes,24T09@186801|Clostridia,3Y0JX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02103	1121115.AXVN01000042_gene3028	0.0	1356.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,3XYTQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
HGCANGJP_02104	1121115.AXVN01000042_gene3029	1.31e-109	316.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
HGCANGJP_02105	1121115.AXVN01000042_gene3030	4.78e-249	683.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3XYWD@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
HGCANGJP_02106	1121115.AXVN01000042_gene3031	1.83e-148	418.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3XYPA@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
HGCANGJP_02107	1121115.AXVN01000042_gene3032	1.14e-314	856.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3XYZ3@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
HGCANGJP_02108	457412.RSAG_01710	9.73e-179	498.0	28NW4@1|root,32MWE@2|Bacteria,1TUAZ@1239|Firmicutes,259BP@186801|Clostridia,3WPWQ@541000|Ruminococcaceae	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
HGCANGJP_02109	457412.RSAG_01709	9.51e-81	239.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,3WJKW@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HGCANGJP_02110	1121115.AXVN01000042_gene3036	0.0	1553.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3XYKC@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 9.98	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HGCANGJP_02111	1121115.AXVN01000042_gene3037	1.4e-90	265.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,3Y05D@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02112	1121115.AXVN01000042_gene3038	0.0	887.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3XYVQ@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
HGCANGJP_02113	457412.RSAG_01705	2.06e-158	444.0	COG0637@1|root,COG0637@2|Bacteria,1V1IW@1239|Firmicutes,24FZZ@186801|Clostridia,3WRQ7@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	CpXC,HAD_2
HGCANGJP_02114	1121115.AXVN01000042_gene3040	0.0	871.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3Y1DM@572511|Blautia	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HGCANGJP_02115	1121115.AXVN01000042_gene3041	3.21e-209	578.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,24AYF@186801|Clostridia,3Y06U@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_02116	1121115.AXVN01000006_gene2188	1.52e-124	354.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,3XZU8@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
HGCANGJP_02117	457412.RSAG_00839	4.48e-120	343.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
HGCANGJP_02118	1121115.AXVN01000006_gene2186	2.04e-209	579.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3XYQC@572511|Blautia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
HGCANGJP_02119	1121115.AXVN01000006_gene2185	2.65e-203	563.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,3Y05C@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
HGCANGJP_02120	1121115.AXVN01000006_gene2184	5.6e-159	446.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3XZGI@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
HGCANGJP_02121	457412.RSAG_00835	3.9e-268	733.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3WHUE@541000|Ruminococcaceae	186801|Clostridia	C	pyruvate formate lyase activating	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
HGCANGJP_02122	457412.RSAG_00834	0.0	919.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3WGU8@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
HGCANGJP_02123	457412.RSAG_00833	0.0	869.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3WGP4@541000|Ruminococcaceae	186801|Clostridia	P	K transport systems, NAD-binding component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
HGCANGJP_02124	1121115.AXVN01000006_gene2180	5.3e-109	313.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3XYJ2@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
HGCANGJP_02125	457412.RSAG_00801	0.0	919.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WIPD@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_02127	457412.RSAG_00798	2.97e-42	142.0	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia,3WQH6@541000|Ruminococcaceae	186801|Clostridia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
HGCANGJP_02128	1121115.AXVN01000192_gene2633	5.86e-122	362.0	COG3039@1|root,COG3039@2|Bacteria,1U377@1239|Firmicutes,24ASA@186801|Clostridia,3Y1AH@572511|Blautia	186801|Clostridia	L	COG NOG25267 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
HGCANGJP_02129	1121115.AXVN01000006_gene2172	1.15e-25	95.1	2FGK7@1|root,348FZ@2|Bacteria,1W09F@1239|Firmicutes,25375@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02130	511680.BUTYVIB_00702	2.12e-20	89.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,4BWG0@830|Butyrivibrio	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HGCANGJP_02131	511680.BUTYVIB_00701	4.01e-88	267.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,4BX3E@830|Butyrivibrio	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
HGCANGJP_02133	397291.C804_04886	1.17e-90	277.0	COG4977@1|root,COG4977@2|Bacteria,1UJZB@1239|Firmicutes,25FFH@186801|Clostridia,27NE9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HGCANGJP_02134	1226325.HMPREF1548_05324	2.63e-246	690.0	COG3664@1|root,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia,36GCA@31979|Clostridiaceae	186801|Clostridia	K	family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Glyco_hydro_39,HTH_18
HGCANGJP_02135	642492.Clole_1281	1.85e-302	828.0	COG3534@1|root,COG3534@2|Bacteria,1TPJ0@1239|Firmicutes,25EH6@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
HGCANGJP_02136	1392493.JIAB01000001_gene893	2.8e-94	307.0	COG3693@1|root,COG3693@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,27K6N@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate family 9 binding domain-like	-	-	3.2.1.4,3.2.1.8	ko:K01179,ko:K01181	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM9_1,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1,SLH
HGCANGJP_02137	1122918.KB907282_gene4946	1.28e-133	412.0	COG3250@1|root,COG3250@2|Bacteria,1TQYV@1239|Firmicutes,4HZPR@91061|Bacilli,26XZD@186822|Paenibacillaceae	91061|Bacilli	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
HGCANGJP_02138	1469948.JPNB01000002_gene2919	2.81e-200	580.0	COG2972@1|root,COG2972@2|Bacteria,1TPUF@1239|Firmicutes,2491H@186801|Clostridia,36DCG@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
HGCANGJP_02139	585394.RHOM_05765	2.4e-216	616.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UYK2@1239|Firmicutes,247MJ@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
HGCANGJP_02140	397291.C804_04825	0.0	889.0	COG1653@1|root,COG1653@2|Bacteria,1TQWF@1239|Firmicutes,24CWD@186801|Clostridia,27IIE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02141	585394.RHOM_05775	4.69e-185	519.0	COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,24YP3@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
HGCANGJP_02142	397291.C804_04827	3.06e-176	495.0	COG0395@1|root,COG0395@2|Bacteria,1TP14@1239|Firmicutes,2481Z@186801|Clostridia,27KBY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
HGCANGJP_02143	658655.HMPREF0988_00807	0.0	997.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27J28@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_02144	658086.HMPREF0994_04889	3.03e-40	145.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,27MVA@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
HGCANGJP_02145	1121115.AXVN01000012_gene3117	1.46e-289	799.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3Y0TG@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HGCANGJP_02146	1121115.AXVN01000006_gene2104	8.01e-17	81.6	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3XYNG@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HGCANGJP_02148	457412.RSAG_00426	0.0	1008.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae	186801|Clostridia	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
HGCANGJP_02149	1121115.AXVN01000004_gene1989	2.44e-42	140.0	2CIA0@1|root,341N9@2|Bacteria,1VY7T@1239|Firmicutes,251RU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
HGCANGJP_02152	1256908.HMPREF0373_02455	7.72e-69	209.0	COG4219@1|root,COG4219@2|Bacteria,1V1YX@1239|Firmicutes,24FVT@186801|Clostridia	186801|Clostridia	KT	Domain of unknown function (DUF4825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825
HGCANGJP_02153	658088.HMPREF0987_00262	2.32e-42	141.0	2BCGS@1|root,3262J@2|Bacteria,1US1R@1239|Firmicutes,25A02@186801|Clostridia,27PFM@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
HGCANGJP_02157	1280685.AUKC01000016_gene450	6.06e-38	130.0	295RU@1|root,2ZT35@2|Bacteria,1V63F@1239|Firmicutes,25J4F@186801|Clostridia,4C1CX@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
HGCANGJP_02158	1256908.HMPREF0373_03362	6.11e-277	759.0	COG1277@1|root,COG1277@2|Bacteria,1TSXC@1239|Firmicutes,24CZ4@186801|Clostridia,25VPR@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
HGCANGJP_02159	742740.HMPREF9474_04629	3.06e-206	571.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,2203T@1506553|Lachnoclostridium	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_02160	1256908.HMPREF0373_03360	5.5e-241	664.0	COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,24AV5@186801|Clostridia,25VNN@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	vanS	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_02161	1256908.HMPREF0373_03359	3.04e-105	305.0	COG4767@1|root,COG4767@2|Bacteria,1V7FP@1239|Firmicutes,24IQ9@186801|Clostridia,25WTP@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HGCANGJP_02162	411469.EUBHAL_01193	7.36e-161	451.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25UVX@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K18349	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_02163	457412.RSAG_00432	1.44e-76	232.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WRUB@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_02164	457412.RSAG_00431	3.9e-209	593.0	2E6HB@1|root,3314J@2|Bacteria,1VGBM@1239|Firmicutes,24T1M@186801|Clostridia,3WMCU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02165	457412.RSAG_00433	0.0	1047.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,24A30@186801|Clostridia,3WJX1@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
HGCANGJP_02166	457412.RSAG_00434	1.62e-83	247.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes,24R6S@186801|Clostridia,3WKEQ@541000|Ruminococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HGCANGJP_02167	457412.RSAG_00435	2.42e-161	457.0	2EYFT@1|root,33RPP@2|Bacteria,1VSB0@1239|Firmicutes,24XZU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02168	457412.RSAG_04743	7.8e-54	174.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS_7,Response_reg
HGCANGJP_02169	515620.EUBELI_20438	9.66e-92	279.0	COG0834@1|root,COG0834@2|Bacteria,1UYKY@1239|Firmicutes,24C0B@186801|Clostridia,25VI4@186806|Eubacteriaceae	186801|Clostridia	ET	substrate-binding protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HGCANGJP_02170	1121115.AXVN01000004_gene1998	2.32e-303	827.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,3Y01I@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,HisKA
HGCANGJP_02171	1121115.AXVN01000004_gene1999	2.49e-166	465.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3Y09B@572511|Blautia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_02172	457412.RSAG_00475	1.4e-188	523.0	COG0768@1|root,COG0768@2|Bacteria,1V1CI@1239|Firmicutes,24GWI@186801|Clostridia,3WRJI@541000|Ruminococcaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
HGCANGJP_02173	457412.RSAG_00476	5.43e-194	539.0	COG1266@1|root,COG1266@2|Bacteria,1USCY@1239|Firmicutes,24F5M@186801|Clostridia,3WMPA@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
HGCANGJP_02174	1121115.AXVN01000004_gene2002	0.0	1196.0	2EXAA@1|root,33QKY@2|Bacteria,1VU9D@1239|Firmicutes,24Y4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02175	1121115.AXVN01000004_gene2003	2.19e-111	320.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3Y0EF@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_02176	457412.RSAG_00479	2.48e-135	384.0	2DPKP@1|root,332J8@2|Bacteria,1VU7P@1239|Firmicutes,24YII@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02177	457412.RSAG_00480	1.53e-47	152.0	2CAM5@1|root,3441D@2|Bacteria,1VZ09@1239|Firmicutes,252SV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02178	457412.RSAG_00481	1.09e-105	305.0	2A2TB@1|root,30R6U@2|Bacteria,1V47K@1239|Firmicutes,24IKY@186801|Clostridia,3WPJ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02179	457412.RSAG_00482	0.0	967.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WH27@541000|Ruminococcaceae	186801|Clostridia	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HGCANGJP_02180	457412.RSAG_00483	0.0	926.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3WM85@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HGCANGJP_02181	457412.RSAG_00484	7.22e-119	340.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3WJXC@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_02182	457412.RSAG_00485	1.94e-71	215.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia	186801|Clostridia	G	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
HGCANGJP_02183	457412.RSAG_00486	1.11e-263	722.0	2ACB9@1|root,311W7@2|Bacteria,1V49X@1239|Firmicutes,24NF4@186801|Clostridia,3WJZP@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HGCANGJP_02184	457412.RSAG_00487	1.18e-121	347.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WJQH@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_02185	457412.RSAG_02479	0.0	1644.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
HGCANGJP_02186	1121115.AXVN01000101_gene821	1.44e-35	120.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3Y0SX@572511|Blautia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
HGCANGJP_02187	457412.RSAG_02477	0.0	1011.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
HGCANGJP_02188	457412.RSAG_02476	7.25e-240	659.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_02189	1121115.AXVN01000101_gene818	0.0	888.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYY1@572511|Blautia	186801|Clostridia	P	COG COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HGCANGJP_02190	1121115.AXVN01000101_gene817	2.6e-208	576.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3Y0AZ@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_02191	1121115.AXVN01000101_gene816	7.17e-104	300.0	COG1846@1|root,COG1846@2|Bacteria,1VFS1@1239|Firmicutes,24QXV@186801|Clostridia,3Y0D8@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
HGCANGJP_02192	1121115.AXVN01000101_gene815	0.0	1323.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_02193	457412.RSAG_02471	0.0	1168.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
HGCANGJP_02194	1121115.AXVN01000051_gene792	0.0	1327.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,3XZ0C@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	helD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
HGCANGJP_02195	1121115.AXVN01000051_gene793	8.53e-192	541.0	2EWK9@1|root,33PYD@2|Bacteria,1VTXK@1239|Firmicutes,24ZC9@186801|Clostridia,3Y0MZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02196	457412.RSAG_02468	2.07e-196	544.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,3WSIZ@541000|Ruminococcaceae	186801|Clostridia	S	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
HGCANGJP_02197	1121115.AXVN01000051_gene795	1.35e-203	564.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3XYXT@572511|Blautia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
HGCANGJP_02198	457412.RSAG_02465	0.0	1287.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
HGCANGJP_02199	457412.RSAG_02464	1.72e-88	261.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,3WK5R@541000|Ruminococcaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02200	1121115.AXVN01000051_gene798	0.0	2149.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3XYMT@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
HGCANGJP_02201	1121115.AXVN01000051_gene799	0.0	2399.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3XYPU@572511|Blautia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
HGCANGJP_02202	457412.RSAG_02461	0.0	947.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3WGN3@541000|Ruminococcaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
HGCANGJP_02203	1121115.AXVN01000051_gene801	2.25e-70	212.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3Y09J@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
HGCANGJP_02204	1121115.AXVN01000051_gene802	4.49e-121	350.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia,3Y0B4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HGCANGJP_02205	1121115.AXVN01000051_gene803	2.06e-143	414.0	2DN7I@1|root,32VZ1@2|Bacteria,1UJVJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HGCANGJP_02206	1121115.AXVN01000051_gene804	6.14e-39	129.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,3Y0IZ@572511|Blautia	186801|Clostridia	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	PspC
HGCANGJP_02207	1121115.AXVN01000051_gene805	2.36e-33	115.0	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
HGCANGJP_02209	1121115.AXVN01000118_gene3305	3.32e-135	383.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,3XZYB@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
HGCANGJP_02210	457412.RSAG_01740	5.22e-173	483.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WGPU@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
HGCANGJP_02211	457412.RSAG_01741	2.48e-106	307.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
HGCANGJP_02212	457412.RSAG_01742	0.0	923.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
HGCANGJP_02213	1121115.AXVN01000118_gene3309	7.92e-113	323.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3XZW5@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
HGCANGJP_02214	1121115.AXVN01000118_gene3310	2.64e-304	830.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25AGX@186801|Clostridia,3XZXG@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
HGCANGJP_02215	457412.RSAG_01745	0.0	875.0	COG2367@1|root,COG2367@2|Bacteria,1VCFX@1239|Firmicutes,24D4X@186801|Clostridia,3WKRB@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HGCANGJP_02216	457412.RSAG_01746	0.0	1582.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3WGEC@541000|Ruminococcaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
HGCANGJP_02217	397290.C810_01428	2.14e-99	300.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,27K2N@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HGCANGJP_02218	500632.CLONEX_04241	3.47e-35	132.0	COG3039@1|root,COG3039@2|Bacteria,1TRUS@1239|Firmicutes,24AH8@186801|Clostridia	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2,DUF772
HGCANGJP_02219	710685.MycrhN_1488	5.07e-27	127.0	COG4403@1|root,COG4403@2|Bacteria,2GKVV@201174|Actinobacteria,2373A@1762|Mycobacteriaceae	201174|Actinobacteria	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
HGCANGJP_02223	1125973.JNLC01000014_gene2410	8.92e-06	57.4	COG0790@1|root,COG4249@1|root,COG0790@2|Bacteria,COG4249@2|Bacteria,1MX7B@1224|Proteobacteria,2TUDI@28211|Alphaproteobacteria,3JRZ9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Caspase domain	MA20_30665	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_C14,SH3_3
HGCANGJP_02229	411483.FAEPRAA2165_03283	2.75e-113	394.0	COG1674@1|root,COG1674@2|Bacteria,1V7UZ@1239|Firmicutes,24PWS@186801|Clostridia,3WQ7W@541000|Ruminococcaceae	186801|Clostridia	D	FtsK SpoIIIE family protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
HGCANGJP_02232	1408473.JHXO01000008_gene2686	2.14e-107	330.0	COG0476@1|root,COG0476@2|Bacteria,4NY30@976|Bacteroidetes,2FW27@200643|Bacteroidia	976|Bacteroidetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
HGCANGJP_02233	411483.FAEPRAA2165_03286	2.84e-63	211.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
HGCANGJP_02234	1408473.JHXO01000008_gene2684	2.08e-43	149.0	2FBW9@1|root,3440U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02236	525919.Apre_1655	1.52e-07	52.4	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia,22HXG@1570339|Peptoniphilaceae	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HGCANGJP_02237	1235799.C818_01943	8.58e-84	267.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,27M2S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
HGCANGJP_02238	1123263.AUKY01000003_gene276	1.17e-48	158.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,3VS4H@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_02239	518637.EUBIFOR_00810	1.84e-29	105.0	2EI8P@1|root,332BW@2|Bacteria,1VFSF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02240	1123298.KB904121_gene1917	3.62e-133	382.0	COG0582@1|root,COG0582@2|Bacteria,1UMEE@1239|Firmicutes,4ITVG@91061|Bacilli	91061|Bacilli	L	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
HGCANGJP_02241	457412.RSAG_04645	0.0	1123.0	COG5263@1|root,COG5263@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02242	457412.RSAG_01929	5.85e-15	75.5	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02243	1121115.AXVN01000098_gene2883	1.29e-26	98.2	COG5464@1|root,COG5464@2|Bacteria,1UHIM@1239|Firmicutes,25QA6@186801|Clostridia,3Y22B@572511|Blautia	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02244	457412.RSAG_00152	2.62e-09	55.1	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02245	457412.RSAG_03051	0.0	1844.0	COG5263@1|root,COG5492@1|root,COG5263@2|Bacteria,COG5492@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02247	457412.RSAG_01929	1.15e-27	110.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02248	457412.RSAG_03050	0.0	1327.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,3WIA4@541000|Ruminococcaceae	186801|Clostridia	L	TopoisomeraseII	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
HGCANGJP_02249	1121115.AXVN01000005_gene2219	0.0	1447.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,3XZJ2@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
HGCANGJP_02250	1121115.AXVN01000005_gene2220	9.83e-106	305.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3Y03N@572511|Blautia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
HGCANGJP_02251	1121115.AXVN01000005_gene2221	1.78e-254	702.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3XZH6@572511|Blautia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
HGCANGJP_02252	1121115.AXVN01000005_gene2222	4.94e-58	179.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3Y0GX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
HGCANGJP_02253	457412.RSAG_03045	4.9e-64	195.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,3WM5W@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
HGCANGJP_02254	457412.RSAG_03044	0.0	1601.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
HGCANGJP_02255	1121115.AXVN01000005_gene2225	4.61e-84	248.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3Y0A9@572511|Blautia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
HGCANGJP_02256	457412.RSAG_03042	3.3e-234	644.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
HGCANGJP_02257	457412.RSAG_03041	5.33e-211	583.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,3WH28@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
HGCANGJP_02258	1121115.AXVN01000005_gene2228	1.04e-217	600.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3XZMT@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
HGCANGJP_02259	1121115.AXVN01000005_gene2229	8.72e-53	166.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3Y0EQ@572511|Blautia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
HGCANGJP_02260	457412.RSAG_03038	0.0	1358.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
HGCANGJP_02261	1121115.AXVN01000005_gene2231	5.93e-115	328.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3XZW3@572511|Blautia	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HGCANGJP_02262	1121115.AXVN01000005_gene2232	4.95e-120	343.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24GHG@186801|Clostridia,3XZTE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
HGCANGJP_02263	1121115.AXVN01000005_gene2233	1.92e-284	777.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,249TW@186801|Clostridia,3XZSQ@572511|Blautia	186801|Clostridia	I	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
HGCANGJP_02264	1121115.AXVN01000005_gene2234	3.68e-190	527.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia,3XZCT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02265	1121115.AXVN01000005_gene2235	0.0	1721.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,3Y17B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HGCANGJP_02266	411462.DORLON_00869	3.84e-162	454.0	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia,27W1X@189330|Dorea	186801|Clostridia	L	COG COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
HGCANGJP_02267	1121115.AXVN01000036_gene2429	0.0	1300.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
HGCANGJP_02268	1121115.AXVN01000036_gene2428	5.7e-262	716.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3XYHE@572511|Blautia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
HGCANGJP_02269	1121115.AXVN01000036_gene2427	2.64e-109	315.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,3XZYM@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
HGCANGJP_02270	457412.RSAG_02341	0.0	898.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,3WGZQ@541000|Ruminococcaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
HGCANGJP_02271	1121115.AXVN01000036_gene2417	1.02e-46	149.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3Y0G4@572511|Blautia	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
HGCANGJP_02272	1121115.AXVN01000036_gene2416	7.04e-221	610.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3XYUQ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
HGCANGJP_02273	1121115.AXVN01000036_gene2415	1.69e-232	639.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3XZ9I@572511|Blautia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
HGCANGJP_02274	1121115.AXVN01000036_gene2414	1.09e-249	686.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3XYXD@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
HGCANGJP_02275	457412.RSAG_02345	8.57e-218	601.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3WHDJ@541000|Ruminococcaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HGCANGJP_02276	1121115.AXVN01000036_gene2412	0.0	886.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3XYSV@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
HGCANGJP_02277	457412.RSAG_02347	2.31e-235	649.0	COG0457@1|root,COG0457@2|Bacteria,1V6VP@1239|Firmicutes,258AK@186801|Clostridia,3WMBI@541000|Ruminococcaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
HGCANGJP_02278	1121115.AXVN01000036_gene2410	1.25e-284	779.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3XZ8M@572511|Blautia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
HGCANGJP_02279	457412.RSAG_02349	0.0	1610.0	COG0695@1|root,COG1328@1|root,COG0695@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WGUQ@541000|Ruminococcaceae	186801|Clostridia	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,Glutaredoxin,NRDD
HGCANGJP_02280	1121115.AXVN01000036_gene2408	6.86e-97	282.0	COG4747@1|root,COG4747@2|Bacteria,1V8ZY@1239|Firmicutes,24NAM@186801|Clostridia,3Y0M9@572511|Blautia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02281	1121115.AXVN01000036_gene2407	6.82e-99	287.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0EE@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HGCANGJP_02282	457412.RSAG_02352	1.73e-219	605.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HGCANGJP_02283	1121115.AXVN01000036_gene2405	3.9e-269	735.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3XZBE@572511|Blautia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
HGCANGJP_02284	1121115.AXVN01000036_gene2404	7.8e-315	857.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HGCANGJP_02285	457412.RSAG_02355	3.79e-190	529.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3WIK3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
HGCANGJP_02287	1121115.AXVN01000016_gene3696	6.37e-102	294.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,25MW0@186801|Clostridia,3Y26V@572511|Blautia	186801|Clostridia	P	Ferric uptake regulator family	-	-	-	-	-	-	-	-	-	-	-	-	FUR
HGCANGJP_02288	457412.RSAG_02357	2.47e-211	587.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
HGCANGJP_02289	1121115.AXVN01000016_gene3694	2.52e-153	432.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3XZSK@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.99	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
HGCANGJP_02290	1121115.AXVN01000016_gene3693	1.17e-58	182.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,3Y0E3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
HGCANGJP_02291	1121115.AXVN01000016_gene3692	1.94e-204	565.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3XZFN@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
HGCANGJP_02292	1121115.AXVN01000016_gene3691	2.85e-180	503.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3XYTF@572511|Blautia	186801|Clostridia	ET	COG COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HGCANGJP_02293	1121115.AXVN01000016_gene3690	1.22e-157	443.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3XZT5@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
HGCANGJP_02294	457412.RSAG_02362	1.89e-171	479.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WGJA@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HGCANGJP_02295	457412.RSAG_02363	4.94e-218	602.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3WND9@541000|Ruminococcaceae	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
HGCANGJP_02296	457412.RSAG_02364	1.82e-97	283.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,3WKBA@541000|Ruminococcaceae	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
HGCANGJP_02297	1121115.AXVN01000016_gene3686	1.59e-244	671.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3XYZ8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
HGCANGJP_02298	457412.RSAG_02366	1.94e-194	544.0	2EYFJ@1|root,33RPG@2|Bacteria,1VSB2@1239|Firmicutes,24ZFW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02299	1121115.AXVN01000016_gene3683	0.0	1450.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3XYTU@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
HGCANGJP_02300	457412.RSAG_02368	2.85e-214	592.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3WHV4@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HGCANGJP_02301	1121115.AXVN01000016_gene3681	0.0	1024.0	2EX8G@1|root,33QJ9@2|Bacteria,1VTVN@1239|Firmicutes,25FHM@186801|Clostridia,3Y0FY@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02302	1121115.AXVN01000016_gene3680	0.0	973.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3XYZ0@572511|Blautia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HGCANGJP_02303	1121115.AXVN01000016_gene3679	0.0	1446.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3XYQI@572511|Blautia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
HGCANGJP_02304	1121115.AXVN01000016_gene3678	1.18e-108	313.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3Y03J@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HGCANGJP_02305	457412.RSAG_02373	2.68e-226	623.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
HGCANGJP_02306	1121115.AXVN01000016_gene3676	5.34e-150	423.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,3XZPM@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.26	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
HGCANGJP_02307	457412.RSAG_02375	0.0	899.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
HGCANGJP_02308	1121115.AXVN01000016_gene3674	8.97e-252	690.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3XZJW@572511|Blautia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
HGCANGJP_02309	457412.RSAG_02377	1.33e-172	482.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
HGCANGJP_02310	1121115.AXVN01000016_gene3672	0.0	1287.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3XZC8@572511|Blautia	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
HGCANGJP_02311	457412.RSAG_02379	3.21e-211	583.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
HGCANGJP_02312	457412.RSAG_02380	8.05e-157	440.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
HGCANGJP_02313	1121115.AXVN01000016_gene3669	1.44e-169	474.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3Y05M@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
HGCANGJP_02314	1121115.AXVN01000016_gene3668	5.98e-100	290.0	COG1959@1|root,COG1959@2|Bacteria,1W6XJ@1239|Firmicutes,24SDU@186801|Clostridia,3Y0UG@572511|Blautia	186801|Clostridia	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HGCANGJP_02315	1121115.AXVN01000016_gene3667	4.69e-144	406.0	2ES5J@1|root,33JQC@2|Bacteria,1VK71@1239|Firmicutes,24X6X@186801|Clostridia,3Y03E@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
HGCANGJP_02316	411459.RUMOBE_02476	4.68e-152	427.0	COG1309@1|root,COG1309@2|Bacteria,1V6JC@1239|Firmicutes,24MPA@186801|Clostridia,3XZXC@572511|Blautia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HGCANGJP_02317	411459.RUMOBE_02477	1.44e-180	503.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYW4@572511|Blautia	186801|Clostridia	D	Anion-transporting ATPase	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
HGCANGJP_02319	1121115.AXVN01000016_gene3663	3.28e-166	464.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,25BYP@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_02320	1121115.AXVN01000016_gene3662	9.16e-290	794.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,3XZ44@572511|Blautia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_02321	1121115.AXVN01000016_gene3661	0.0	1863.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3XZIP@572511|Blautia	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_02322	1121115.AXVN01000016_gene3660	0.0	1594.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_02323	1121115.AXVN01000016_gene3659	1.08e-144	407.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia,3Y0IX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02324	1121115.AXVN01000016_gene3658	5.7e-260	712.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
HGCANGJP_02325	1121115.AXVN01000016_gene3657	1.25e-240	662.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3XYMQ@572511|Blautia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
HGCANGJP_02326	457412.RSAG_02384	2.79e-102	295.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
HGCANGJP_02327	1121115.AXVN01000016_gene3655	1.55e-223	616.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3XYP8@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
HGCANGJP_02328	1121115.AXVN01000016_gene3654	5.3e-124	354.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia,3Y079@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HGCANGJP_02329	457412.RSAG_02387	0.0	1369.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WI1C@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein dimerisation domain	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
HGCANGJP_02330	457412.RSAG_02388	0.0	1195.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
HGCANGJP_02331	1121115.AXVN01000016_gene3651	4.74e-217	600.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3XZ7U@572511|Blautia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
HGCANGJP_02332	1121115.AXVN01000016_gene3650	0.0	897.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3XYZG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
HGCANGJP_02333	457412.RSAG_02391	4.12e-253	695.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
HGCANGJP_02334	457412.RSAG_02392	2.79e-312	850.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WG8Y@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
HGCANGJP_02335	457412.RSAG_02393	1.37e-204	573.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,3WMQV@541000|Ruminococcaceae	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
HGCANGJP_02336	457412.RSAG_02394	4.37e-266	731.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
HGCANGJP_02337	1121115.AXVN01000016_gene3645	1.19e-71	215.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia,3Y0IT@572511|Blautia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
HGCANGJP_02338	1121115.AXVN01000015_gene3701	1.08e-107	311.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3XZXW@572511|Blautia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
HGCANGJP_02339	457412.RSAG_02397	6.11e-36	122.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3WMNQ@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
HGCANGJP_02340	1121115.AXVN01000015_gene3702	3.98e-72	217.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3Y03U@572511|Blautia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
HGCANGJP_02341	1121115.AXVN01000015_gene3704	3.62e-268	735.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3XZ26@572511|Blautia	186801|Clostridia	E	COG COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
HGCANGJP_02342	1121115.AXVN01000015_gene3705	3.6e-189	528.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3XYQM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HGCANGJP_02343	1121115.AXVN01000015_gene3706	4.88e-232	641.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3XYTB@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
HGCANGJP_02344	1121115.AXVN01000015_gene3707	8.69e-180	500.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3XZSC@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
HGCANGJP_02345	1121115.AXVN01000015_gene3708	2.38e-160	450.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3XZDH@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
HGCANGJP_02346	457412.RSAG_02402	3.19e-146	412.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,3WITW@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_02347	457412.RSAG_02403	8.33e-311	847.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
HGCANGJP_02348	1121115.AXVN01000015_gene3717	2.95e-117	335.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,3Y078@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
HGCANGJP_02349	1121115.AXVN01000015_gene3718	1.82e-225	620.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,3XYHJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
HGCANGJP_02350	457412.RSAG_02406	3.59e-150	424.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
HGCANGJP_02351	1121115.AXVN01000015_gene3720	1.07e-167	469.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24H9B@186801|Clostridia,3XZX4@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
HGCANGJP_02352	1121115.AXVN01000015_gene3721	1.57e-237	654.0	COG1879@1|root,COG1879@2|Bacteria,1V3FA@1239|Firmicutes,24G5Q@186801|Clostridia,3Y1NU@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HGCANGJP_02353	1121115.AXVN01000015_gene3722	0.0	921.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3Y15R@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
HGCANGJP_02354	1121115.AXVN01000015_gene3723	0.0	1033.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
HGCANGJP_02355	1121115.AXVN01000015_gene3724	6.65e-259	710.0	COG4213@1|root,COG4213@2|Bacteria,1UNTA@1239|Firmicutes	1239|Firmicutes	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
HGCANGJP_02356	1121115.AXVN01000015_gene3725	8.02e-255	699.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
HGCANGJP_02357	457412.RSAG_02414	0.0	991.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WH2F@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, ATPase component	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
HGCANGJP_02358	457412.RSAG_02415	1.58e-265	729.0	COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,24XS9@186801|Clostridia,3WGFE@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	xylH	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
HGCANGJP_02359	457412.RSAG_02416	1.62e-169	473.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3WIW2@541000|Ruminococcaceae	186801|Clostridia	E	PHP domain protein	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
HGCANGJP_02360	1121115.AXVN01000015_gene3729	2.4e-65	199.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3Y07E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
HGCANGJP_02361	457412.RSAG_02418	0.0	2172.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
HGCANGJP_02363	457412.RSAG_02419	1.93e-243	668.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,3WGK0@541000|Ruminococcaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
HGCANGJP_02364	457412.RSAG_02421	0.0	1521.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3WGBC@541000|Ruminococcaceae	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
HGCANGJP_02365	1121115.AXVN01000015_gene3733	1.67e-222	612.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3XZEN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
HGCANGJP_02366	457412.RSAG_02423	2.96e-316	860.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3WIWK@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02367	457412.RSAG_02424	8.19e-212	585.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,3WHPR@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_02368	1121115.AXVN01000015_gene3736	4.82e-188	523.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3Y0FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_02369	1121115.AXVN01000015_gene3737	1.1e-153	432.0	COG5578@1|root,COG5578@2|Bacteria,1V5CK@1239|Firmicutes,24IZD@186801|Clostridia,3Y1SW@572511|Blautia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
HGCANGJP_02370	1121115.AXVN01000015_gene3738	0.0	1518.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3XYN9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
HGCANGJP_02371	1121115.AXVN01000015_gene3739	0.0	1215.0	COG2972@1|root,COG2972@2|Bacteria,1VS09@1239|Firmicutes,24AV3@186801|Clostridia,3Y1HV@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
HGCANGJP_02372	1121115.AXVN01000015_gene3740	2.1e-165	464.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UUUY@1239|Firmicutes,25KCT@186801|Clostridia,3Y1GV@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
HGCANGJP_02373	1121115.AXVN01000015_gene3741	1.19e-297	812.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,2497E@186801|Clostridia,3Y0JS@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
HGCANGJP_02374	1121115.AXVN01000015_gene3742	1.25e-207	575.0	COG1175@1|root,COG1175@2|Bacteria,1UZE5@1239|Firmicutes,25MIN@186801|Clostridia,3Y15U@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02375	1121115.AXVN01000015_gene3743	6.12e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TSM1@1239|Firmicutes,25C4V@186801|Clostridia,3Y1GS@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02376	1121115.AXVN01000015_gene3744	0.0	1425.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,3Y2CQ@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
HGCANGJP_02377	1121115.AXVN01000015_gene3745	0.0	1330.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
HGCANGJP_02378	457412.RSAG_02428	1.99e-139	394.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,3WS7D@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
HGCANGJP_02379	1121115.AXVN01000022_gene1732	0.0	975.0	COG3757@1|root,COG5263@1|root,COG3757@2|Bacteria,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3Y010@572511|Blautia	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glyco_hydro_25
HGCANGJP_02380	457412.RSAG_02130	4.97e-70	211.0	COG2076@1|root,COG2076@2|Bacteria,1VFDI@1239|Firmicutes,24S4I@186801|Clostridia,3WKQ8@541000|Ruminococcaceae	186801|Clostridia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HGCANGJP_02381	1121115.AXVN01000022_gene1730	1.84e-76	228.0	COG0697@1|root,COG0697@2|Bacteria,1UHS0@1239|Firmicutes,25FFB@186801|Clostridia,3Y0C7@572511|Blautia	186801|Clostridia	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HGCANGJP_02382	1121115.AXVN01000022_gene1729	3.35e-218	602.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,3XZM2@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
HGCANGJP_02383	1121115.AXVN01000022_gene1728	5.3e-240	658.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3Y0S8@572511|Blautia	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02384	457412.RSAG_02126	0.0	875.0	COG0027@1|root,COG0027@2|Bacteria,1UKI5@1239|Firmicutes,25FXP@186801|Clostridia,3WIMW@541000|Ruminococcaceae	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
HGCANGJP_02385	457412.RSAG_02125	1.57e-283	773.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3WI1W@541000|Ruminococcaceae	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
HGCANGJP_02386	457412.RSAG_02124	9.67e-291	796.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HGCANGJP_02387	1121115.AXVN01000022_gene1724	1.89e-138	390.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3XYH7@572511|Blautia	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
HGCANGJP_02388	457412.RSAG_02122	7.18e-193	535.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3WKBW@541000|Ruminococcaceae	186801|Clostridia	GM	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
HGCANGJP_02389	1121115.AXVN01000072_gene3917	3.01e-311	847.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
HGCANGJP_02390	457412.RSAG_02120	0.0	1454.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,3WN5Y@541000|Ruminococcaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
HGCANGJP_02391	457412.RSAG_02119	0.0	1654.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
HGCANGJP_02392	457412.RSAG_02118	0.0	1642.0	COG1216@1|root,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
HGCANGJP_02393	457412.RSAG_02117	0.0	991.0	COG1807@1|root,COG1807@2|Bacteria,1V22V@1239|Firmicutes,24GKH@186801|Clostridia,3WK06@541000|Ruminococcaceae	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT,PMT_2
HGCANGJP_02394	457412.RSAG_02116	1.86e-290	796.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
HGCANGJP_02395	457412.RSAG_02115	0.0	1305.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
HGCANGJP_02396	1121115.AXVN01000072_gene3910	1.85e-239	657.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3XYQG@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
HGCANGJP_02397	457412.RSAG_02113	0.0	912.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3WRHZ@541000|Ruminococcaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
HGCANGJP_02398	457412.RSAG_02112	5.64e-278	767.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,3WGW9@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
HGCANGJP_02399	457412.RSAG_02111	3.31e-240	658.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,3WN6M@541000|Ruminococcaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
HGCANGJP_02400	457412.RSAG_02110	0.0	878.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WH0E@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HGCANGJP_02401	397288.C806_01616	2e-48	154.0	2CIKK@1|root,32TFN@2|Bacteria,1VAVR@1239|Firmicutes,24PS4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02402	1121115.AXVN01000011_gene3411	0.0	1086.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYKU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_02403	457412.RSAG_02321	0.0	1091.0	COG1961@1|root,COG1961@2|Bacteria,1TQ8Y@1239|Firmicutes,247WD@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_02404	1121115.AXVN01000011_gene3438	0.0	1008.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,3XZC2@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_02405	457412.RSAG_02323	0.0	881.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia,3WJY3@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
HGCANGJP_02406	457412.RSAG_02324	7.78e-158	442.0	28HPF@1|root,2Z98R@2|Bacteria,1UZQH@1239|Firmicutes,24DVV@186801|Clostridia,3WRZF@541000|Ruminococcaceae	186801|Clostridia	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
HGCANGJP_02407	411461.DORFOR_02637	0.0	959.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1TRCK@1239|Firmicutes,24A7A@186801|Clostridia,27WET@189330|Dorea	186801|Clostridia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,dCache_1
HGCANGJP_02408	457412.RSAG_02325	1.29e-171	478.0	COG1489@1|root,COG1489@2|Bacteria,1VTYF@1239|Firmicutes,25E56@186801|Clostridia,3WS62@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
HGCANGJP_02409	457412.RSAG_02327	2.37e-185	516.0	2F1N0@1|root,33UNB@2|Bacteria,1VUUW@1239|Firmicutes,250GG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02410	457412.RSAG_02328	5.8e-147	423.0	2C1YG@1|root,30J7S@2|Bacteria,1TVA7@1239|Firmicutes,25A6I@186801|Clostridia,3WR8T@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02411	457412.RSAG_02329	0.0	1077.0	2DBJI@1|root,2Z9M2@2|Bacteria,1V4CA@1239|Firmicutes,24IGG@186801|Clostridia,3WIQJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
HGCANGJP_02412	457412.RSAG_02330	2.56e-307	840.0	COG4585@1|root,COG4585@2|Bacteria,1V4GJ@1239|Firmicutes,24M3N@186801|Clostridia,3WJCM@541000|Ruminococcaceae	186801|Clostridia	T	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02413	457412.RSAG_02331	7.78e-143	403.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24E7M@186801|Clostridia,3WJQ7@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07694	ko02020,map02020	M00480	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
HGCANGJP_02414	457412.RSAG_02332	1.65e-212	587.0	2BB5X@1|root,324NG@2|Bacteria,1V7KI@1239|Firmicutes,24MCT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02416	1121115.AXVN01000011_gene3445	0.0	1319.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZIE@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,MTHFR_C,RnfC_N,SLBB
HGCANGJP_02417	1121115.AXVN01000011_gene3446	3.47e-154	432.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,3XYYU@572511|Blautia	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	metV	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS18525	MTHFR_C
HGCANGJP_02418	1121115.AXVN01000011_gene3447	1.78e-208	576.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,3XYTN@572511|Blautia	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
HGCANGJP_02419	1121115.AXVN01000036_gene2434	3.53e-200	555.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_02420	1121115.AXVN01000036_gene2433	2.44e-211	584.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_02421	1121115.AXVN01000036_gene2432	0.0	892.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3Y0CH@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02422	1121115.AXVN01000036_gene2431	2.08e-241	663.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,3Y0YZ@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HGCANGJP_02423	1121115.AXVN01000036_gene2430	0.0	1705.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3Y0G0@572511|Blautia	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
HGCANGJP_02424	1121115.AXVN01000130_gene189	2.75e-91	267.0	COG5361@1|root,COG5361@2|Bacteria,1U2H3@1239|Firmicutes,24F4F@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
HGCANGJP_02425	1121115.AXVN01000130_gene188	2.82e-197	546.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3XZ3Q@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HGCANGJP_02426	457412.RSAG_03479	1.6e-103	299.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
HGCANGJP_02427	1121115.AXVN01000130_gene186	6.35e-300	816.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3XYUY@572511|Blautia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
HGCANGJP_02428	1121115.AXVN01000130_gene185	7.39e-113	323.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3XZW2@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HGCANGJP_02429	457412.RSAG_03476	6.23e-304	828.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
HGCANGJP_02430	457412.RSAG_03475	2.28e-113	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WIGV@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
HGCANGJP_02431	457412.RSAG_03474	4.18e-301	821.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	hacA	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
HGCANGJP_02432	457412.RSAG_03473	0.0	1020.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
HGCANGJP_02433	1121115.AXVN01000088_gene4037	4.8e-139	392.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HGCANGJP_02434	457412.RSAG_03471	0.0	1593.0	COG4886@1|root,COG4886@2|Bacteria,1UKIE@1239|Firmicutes,25FXV@186801|Clostridia	186801|Clostridia	S	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
HGCANGJP_02435	1121115.AXVN01000088_gene4039	1.53e-299	824.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XYWG@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HGCANGJP_02436	457412.RSAG_03469	9.47e-79	234.0	COG2198@1|root,COG2198@2|Bacteria,1V7T6@1239|Firmicutes,25CZG@186801|Clostridia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
HGCANGJP_02437	1121115.AXVN01000088_gene4041	9.06e-151	424.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3Y0DJ@572511|Blautia	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
HGCANGJP_02438	457412.RSAG_03467	2.44e-192	538.0	COG5263@1|root,COG5263@2|Bacteria,1VQWH@1239|Firmicutes,24ZPP@186801|Clostridia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
HGCANGJP_02439	457412.RSAG_03466	1.39e-152	429.0	2EYGG@1|root,33RQD@2|Bacteria,1VRY6@1239|Firmicutes,24XIB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02440	457412.RSAG_03465	2.6e-186	518.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24XQ2@186801|Clostridia,3WJKU@541000|Ruminococcaceae	186801|Clostridia	V	Vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,Transglut_core
HGCANGJP_02441	1121115.AXVN01000088_gene4046	9.62e-137	397.0	2ECV2@1|root,336SH@2|Bacteria,1VFTD@1239|Firmicutes,24WJ4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02442	457412.RSAG_03463	0.0	1011.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH71@541000|Ruminococcaceae	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
HGCANGJP_02443	457412.RSAG_03462	6.96e-239	656.0	COG2755@1|root,COG2755@2|Bacteria,1VC24@1239|Firmicutes,258FA@186801|Clostridia,3WMJV@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02444	1121115.AXVN01000088_gene4049	0.0	1014.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
HGCANGJP_02445	1121115.AXVN01000088_gene4050	3.66e-296	807.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
HGCANGJP_02446	1121115.AXVN01000088_gene4051	9.66e-46	147.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
HGCANGJP_02447	457412.RSAG_00054	1.69e-125	369.0	2DUPT@1|root,33RMR@2|Bacteria,1UKHV@1239|Firmicutes,25FXD@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HGCANGJP_02448	457412.RSAG_01526	0.0	1123.0	COG2972@1|root,COG2972@2|Bacteria,1UQDY@1239|Firmicutes,249HG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
HGCANGJP_02449	1121115.AXVN01000123_gene2863	1.83e-298	814.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3XZFW@572511|Blautia	186801|Clostridia	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
HGCANGJP_02450	1121115.AXVN01000123_gene2864	1.45e-212	587.0	COG2207@1|root,COG2207@2|Bacteria,1V062@1239|Firmicutes,25B1G@186801|Clostridia,3XZV3@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_02451	457412.RSAG_01535	0.0	1288.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
HGCANGJP_02452	641112.ACOK01000080_gene3238	1.23e-17	76.6	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,3WKEN@541000|Ruminococcaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
HGCANGJP_02453	1235802.C823_00083	5.26e-276	761.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,25V9R@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
HGCANGJP_02454	457412.RSAG_01536	8.2e-265	729.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,249SA@186801|Clostridia,3WP6K@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
HGCANGJP_02455	1121115.AXVN01000123_gene2865	9.23e-218	601.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,3Y07S@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_02456	457412.RSAG_01548	1.14e-254	700.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3WGR3@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
HGCANGJP_02457	457412.RSAG_01549	9.82e-84	247.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,3WM8E@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
HGCANGJP_02458	457412.RSAG_01551	4.56e-269	739.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,3WISY@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
HGCANGJP_02459	1121115.AXVN01000108_gene627	0.0	983.0	COG1621@1|root,COG1621@2|Bacteria,1U0EK@1239|Firmicutes,24AM9@186801|Clostridia,3Y1NF@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF4975)	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	DUF4975,Glyco_hydro_32N
HGCANGJP_02460	1121115.AXVN01000108_gene626	7.71e-192	533.0	COG0395@1|root,COG0395@2|Bacteria,1UXJD@1239|Firmicutes,25M52@186801|Clostridia,3Y1KD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02461	1121115.AXVN01000108_gene625	5.48e-204	565.0	COG1175@1|root,COG1175@2|Bacteria,1UXJE@1239|Firmicutes,25MIM@186801|Clostridia,3Y1QD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02462	1121115.AXVN01000108_gene624	0.0	876.0	COG1653@1|root,COG1653@2|Bacteria,1UUUK@1239|Firmicutes,25MFP@186801|Clostridia,3Y1WB@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
HGCANGJP_02463	1121115.AXVN01000108_gene623	0.0	1064.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,25B1H@186801|Clostridia,3Y2A1@572511|Blautia	186801|Clostridia	KT	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
HGCANGJP_02464	457412.RSAG_01557	0.0	1159.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24I15@186801|Clostridia,3WP5T@541000|Ruminococcaceae	186801|Clostridia	T	Cache domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
HGCANGJP_02465	1121115.AXVN01000108_gene621	5.83e-100	290.0	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
HGCANGJP_02466	1121115.AXVN01000108_gene620	6.26e-119	341.0	COG3090@1|root,COG3090@2|Bacteria,1V6P9@1239|Firmicutes,24JKS@186801|Clostridia,3XZTR@572511|Blautia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
HGCANGJP_02467	457412.RSAG_01560	0.0	2149.0	COG1593@1|root,COG1638@1|root,COG1593@2|Bacteria,COG1638@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctP
HGCANGJP_02471	33035.JPJF01000041_gene304	5.81e-266	744.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3XZKC@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HGCANGJP_02472	1235792.C808_03247	3.37e-98	301.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24825@186801|Clostridia,27KDW@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HGCANGJP_02473	1235792.C808_03246	1.66e-13	72.8	COG1653@1|root,COG1653@2|Bacteria,1TT4C@1239|Firmicutes,24ET2@186801|Clostridia,27P8U@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
HGCANGJP_02474	1235792.C808_03246	4.74e-224	627.0	COG1653@1|root,COG1653@2|Bacteria,1TT4C@1239|Firmicutes,24ET2@186801|Clostridia,27P8U@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
HGCANGJP_02475	1235792.C808_03245	1.6e-162	460.0	COG1175@1|root,COG1175@2|Bacteria,1UZRP@1239|Firmicutes,249H7@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02476	1235792.C808_03244	4.21e-147	420.0	COG0395@1|root,COG0395@2|Bacteria,1UC1Q@1239|Firmicutes,24BT6@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_02477	1235792.C808_03243	0.0	1075.0	COG1397@1|root,COG1397@2|Bacteria,1TSD8@1239|Firmicutes,248QI@186801|Clostridia,27RJ5@186928|unclassified Lachnospiraceae	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HGCANGJP_02478	1235792.C808_03242	0.0	1030.0	COG1397@1|root,COG1397@2|Bacteria,1TSD8@1239|Firmicutes,248QI@186801|Clostridia,27RJ5@186928|unclassified Lachnospiraceae	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
HGCANGJP_02479	1235792.C808_03241	1.79e-121	357.0	COG0524@1|root,COG0524@2|Bacteria,1V4UX@1239|Firmicutes,24DYY@186801|Clostridia	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
HGCANGJP_02480	1235792.C808_03240	2.37e-169	479.0	COG2820@1|root,COG2820@2|Bacteria,1U04R@1239|Firmicutes,24BZM@186801|Clostridia	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
HGCANGJP_02481	1235792.C808_03239	1.42e-214	599.0	COG0449@1|root,COG0449@2|Bacteria,1V1D3@1239|Firmicutes,24FC5@186801|Clostridia	186801|Clostridia	M	SIS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SIS
HGCANGJP_02482	1235792.C808_03238	4.9e-77	231.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,27QGJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
HGCANGJP_02483	1235792.C808_03237	5.06e-183	514.0	COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,24A4D@186801|Clostridia,27PYF@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
HGCANGJP_02484	1235792.C808_03236	8.34e-192	541.0	COG3613@1|root,COG3613@2|Bacteria,1VFK6@1239|Firmicutes,24RZ5@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
HGCANGJP_02485	1235792.C808_03235	2.92e-130	374.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,27UDM@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
HGCANGJP_02486	1163671.JAGI01000003_gene547	4.09e-206	578.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,36E24@31979|Clostridiaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
HGCANGJP_02487	1349820.M707_06150	4.68e-12	70.5	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,1WB9X@1268|Micrococcaceae	201174|Actinobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
HGCANGJP_02488	1235792.C808_02668	3.39e-11	68.9	COG0664@1|root,COG0664@2|Bacteria,1TS68@1239|Firmicutes,25D2G@186801|Clostridia	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
HGCANGJP_02489	457412.RSAG_01411	6.34e-222	610.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
HGCANGJP_02490	1226325.HMPREF1548_06045	1.52e-53	170.0	COG1961@1|root,COG1961@2|Bacteria,1VTW1@1239|Firmicutes,24Z4E@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
HGCANGJP_02491	1226325.HMPREF1548_06044	0.0	1108.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,36DU1@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_02492	457412.RSAG_03422	2.86e-147	422.0	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,3WN05@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HGCANGJP_02493	457412.RSAG_04707	1.77e-60	187.0	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HGCANGJP_02494	1256908.HMPREF0373_01457	0.0	1020.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1TRCK@1239|Firmicutes,24A7A@186801|Clostridia,25XIB@186806|Eubacteriaceae	186801|Clostridia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,dCache_1
HGCANGJP_02495	411459.RUMOBE_02564	0.0	1206.0	COG1653@1|root,COG1653@2|Bacteria,1UUVC@1239|Firmicutes,25MFT@186801|Clostridia,3Y274@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
HGCANGJP_02496	411459.RUMOBE_02565	0.0	1358.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3XZ5S@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
HGCANGJP_02497	411459.RUMOBE_02566	1.18e-313	876.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y28F@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
HGCANGJP_02498	411459.RUMOBE_02567	4.94e-114	341.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3Y0HN@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,Response_reg,Rrf2
HGCANGJP_02501	457412.RSAG_00888	1.48e-175	490.0	COG0716@1|root,COG1145@1|root,COG0716@2|Bacteria,COG1145@2|Bacteria,1VSX9@1239|Firmicutes,24ZRM@186801|Clostridia,3WSJJ@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
HGCANGJP_02503	457412.RSAG_00886	3.53e-277	757.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1
HGCANGJP_02504	457412.RSAG_00885	6.42e-192	534.0	COG1737@1|root,COG1737@2|Bacteria,1VBUB@1239|Firmicutes,24MTV@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HGCANGJP_02505	457412.RSAG_00884	1.63e-52	165.0	2E714@1|root,331JV@2|Bacteria,1VQIV@1239|Firmicutes,251NJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02506	457412.RSAG_00883	0.0	933.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
HGCANGJP_02507	457412.RSAG_00882	2.92e-183	509.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia,3WMNU@541000|Ruminococcaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HGCANGJP_02509	457412.RSAG_00880	0.0	1110.0	COG1961@1|root,COG1961@2|Bacteria,1TWK9@1239|Firmicutes,24C30@186801|Clostridia,3WHD6@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
HGCANGJP_02510	457412.RSAG_00879	3.81e-176	506.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02511	457412.RSAG_00878	0.0	1761.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia,3WHD4@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
HGCANGJP_02512	1121115.AXVN01000054_gene1870	3.72e-158	442.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3XZP9@572511|Blautia	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
HGCANGJP_02513	1121115.AXVN01000054_gene1871	3.84e-300	817.0	29WP9@1|root,30IA6@2|Bacteria,1V4GZ@1239|Firmicutes,24HWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02514	457412.RSAG_02721	0.0	1493.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
HGCANGJP_02515	1121115.AXVN01000054_gene1873	1.21e-212	587.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24I3P@186801|Clostridia,3Y1VY@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_02516	457412.RSAG_02719	4.24e-183	511.0	COG3290@1|root,COG3290@2|Bacteria,1VDUW@1239|Firmicutes,24QIG@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_02517	457412.RSAG_02718	6.43e-211	584.0	2EZ41@1|root,33SA8@2|Bacteria,1VSVN@1239|Firmicutes,24XVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02518	457412.RSAG_02717	3.98e-170	475.0	COG3279@1|root,COG3279@2|Bacteria,1VC9Q@1239|Firmicutes,24PSE@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_02519	457412.RSAG_02716	0.0	1063.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3WH77@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_02520	1121115.AXVN01000054_gene1879	3.75e-63	193.0	COG2026@1|root,COG2026@2|Bacteria,1V7AZ@1239|Firmicutes,24KDM@186801|Clostridia	186801|Clostridia	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE-like_toxin
HGCANGJP_02521	1121115.AXVN01000054_gene1880	1.19e-80	239.0	COG2002@1|root,COG2002@2|Bacteria,1V8G8@1239|Firmicutes,24JVE@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02522	1121115.AXVN01000054_gene1881	1.34e-232	640.0	28K5V@1|root,2Z9UD@2|Bacteria,1V0GM@1239|Firmicutes,24EZ5@186801|Clostridia,3Y13M@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3878
HGCANGJP_02523	457412.RSAG_02712	2.69e-186	518.0	COG2206@1|root,COG2206@2|Bacteria,1V23X@1239|Firmicutes,24GQ5@186801|Clostridia,3WKDD@541000|Ruminococcaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
HGCANGJP_02524	457412.RSAG_02711	4.06e-134	380.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WK2K@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
HGCANGJP_02525	457412.RSAG_02710	1.59e-308	839.0	COG1379@1|root,COG1379@2|Bacteria	2|Bacteria	-	-	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
HGCANGJP_02526	457412.RSAG_02709	1.4e-113	325.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia,3WJE3@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
HGCANGJP_02527	457412.RSAG_02708	6.08e-106	305.0	2DV0M@1|root,32UY9@2|Bacteria,1VC55@1239|Firmicutes,24TS3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02528	457412.RSAG_02707	1.29e-106	307.0	2BZUE@1|root,31TAF@2|Bacteria,1URY6@1239|Firmicutes,24XVK@186801|Clostridia,3WQSR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02529	457412.RSAG_02706	6.5e-73	219.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3WK33@541000|Ruminococcaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
HGCANGJP_02530	457412.RSAG_02705	2.87e-133	381.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3WI9G@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
HGCANGJP_02531	1121115.AXVN01000054_gene1891	2.4e-30	108.0	2C1K5@1|root,3415T@2|Bacteria,1VY97@1239|Firmicutes,2522U@186801|Clostridia,3Y25V@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02532	457412.RSAG_02702	1.38e-227	627.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
HGCANGJP_02533	1121115.AXVN01000054_gene1893	1.11e-173	485.0	2E77V@1|root,32VJN@2|Bacteria,1VA37@1239|Firmicutes,24P5M@186801|Clostridia,3Y1P9@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02534	457412.RSAG_02700	1.31e-108	313.0	2BWHH@1|root,33G8D@2|Bacteria,1VM1X@1239|Firmicutes,24W5T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02535	1121115.AXVN01000054_gene1895	3.36e-117	335.0	COG1595@1|root,COG1595@2|Bacteria,1VB8F@1239|Firmicutes,24PH6@186801|Clostridia,3Y1N5@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_02536	1121115.AXVN01000054_gene1896	1.29e-281	769.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3XZ3U@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HGCANGJP_02537	457412.RSAG_02697	3.21e-211	583.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
HGCANGJP_02538	1121115.AXVN01000054_gene1898	2.87e-269	738.0	COG3103@1|root,COG3103@2|Bacteria,1UG5Z@1239|Firmicutes,25NDX@186801|Clostridia,3Y048@572511|Blautia	186801|Clostridia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02539	457412.RSAG_02693	3.92e-123	352.0	COG3275@1|root,COG3275@2|Bacteria,1UJ12@1239|Firmicutes,24Q7D@186801|Clostridia,3WKDP@541000|Ruminococcaceae	186801|Clostridia	T	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
HGCANGJP_02540	457412.RSAG_00243	4.22e-136	385.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WJWK@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
HGCANGJP_02541	457412.RSAG_00242	2.71e-193	536.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3WIEX@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
HGCANGJP_02542	1121115.AXVN01000017_gene258	1.7e-111	320.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3XZVY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HGCANGJP_02543	457412.RSAG_00240	0.0	1608.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HGCANGJP_02544	1121115.AXVN01000017_gene256	1.43e-252	694.0	2BDSU@1|root,327GK@2|Bacteria,1UTCR@1239|Firmicutes,258AQ@186801|Clostridia,3Y1YM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02545	1121115.AXVN01000017_gene255	4.36e-204	564.0	2A5RW@1|root,30UGW@2|Bacteria,1US7T@1239|Firmicutes,25A6N@186801|Clostridia,3Y26D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02546	457412.RSAG_00237	0.0	1009.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WGRM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	mleN_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
HGCANGJP_02547	411461.DORFOR_01832	3.91e-47	156.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia	186801|Clostridia	L	SMART HTH transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
HGCANGJP_02548	1121115.AXVN01000031_gene328	1.23e-80	239.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia	186801|Clostridia	L	SMART HTH transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
HGCANGJP_02549	411461.DORFOR_01831	1.01e-274	751.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,27WYV@189330|Dorea	186801|Clostridia	L	COG COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
HGCANGJP_02550	457412.RSAG_00235	2.74e-246	682.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
HGCANGJP_02551	457412.RSAG_00236	2.63e-210	582.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
HGCANGJP_02553	457412.RSAG_04728	0.0	1258.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
HGCANGJP_02554	1121115.AXVN01000017_gene249	1.39e-230	634.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3XZIH@572511|Blautia	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
HGCANGJP_02555	457412.RSAG_00230	2.99e-49	156.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes,24R89@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02556	457412.RSAG_00229	6.01e-141	397.0	2ESIJ@1|root,33K39@2|Bacteria,1VP26@1239|Firmicutes,25HRK@186801|Clostridia,3WMIB@541000|Ruminococcaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
HGCANGJP_02557	457412.RSAG_00228	0.0	1047.0	COG0791@1|root,COG0791@2|Bacteria,1UVPP@1239|Firmicutes,25KKC@186801|Clostridia,3WQIY@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
HGCANGJP_02558	1121115.AXVN01000017_gene244	0.0	998.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,3Y18R@572511|Blautia	186801|Clostridia	NU	Type II secretion system (T2SS), protein E, N-terminal domain	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
HGCANGJP_02559	1121115.AXVN01000017_gene243	6.26e-247	679.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3XYY6@572511|Blautia	186801|Clostridia	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
HGCANGJP_02560	1121115.AXVN01000017_gene242	3.94e-260	716.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3Y1N8@572511|Blautia	186801|Clostridia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
HGCANGJP_02561	1121115.AXVN01000017_gene240	5.64e-30	115.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,25FI2@186801|Clostridia,3Y0V4@572511|Blautia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HGCANGJP_02562	1121115.AXVN01000092_gene68	9.48e-204	564.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZD4@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02563	1121115.AXVN01000092_gene69	1.35e-211	586.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02564	1121115.AXVN01000092_gene70	9.26e-310	843.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02565	1121115.AXVN01000092_gene71	5.28e-221	609.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,3XZJ7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_02566	1121115.AXVN01000092_gene72	4.77e-312	849.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02567	457412.RSAG_01993	0.0	864.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
HGCANGJP_02568	1121115.AXVN01000092_gene74	7.77e-159	445.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3XYH5@572511|Blautia	186801|Clostridia	T	positive response regulator for pho regulon	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_02569	1121115.AXVN01000092_gene75	0.0	1095.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3XYUW@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
HGCANGJP_02570	1121115.AXVN01000092_gene76	5.11e-107	309.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,3XZZN@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
HGCANGJP_02571	457412.RSAG_01997	0.0	1795.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3WH08@541000|Ruminococcaceae	186801|Clostridia	J	elongation factor G	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
HGCANGJP_02572	1121115.AXVN01000092_gene78	1.37e-212	589.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,3Y281@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02573	457412.RSAG_01999	2.79e-75	225.0	COG5561@1|root,COG5561@2|Bacteria,1VBDY@1239|Firmicutes,259Y8@186801|Clostridia,3WQWE@541000|Ruminococcaceae	186801|Clostridia	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
HGCANGJP_02574	457412.RSAG_02000	2.89e-173	484.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHNG@541000|Ruminococcaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
HGCANGJP_02575	457412.RSAG_02001	2.33e-241	665.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3WIHA@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HGCANGJP_02576	457412.RSAG_02002	1.03e-246	680.0	COG0614@1|root,COG0614@2|Bacteria,1TSAF@1239|Firmicutes,24ATS@186801|Clostridia,3WI3J@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HGCANGJP_02577	1121115.AXVN01000074_gene2300	1.92e-131	375.0	2DG4Z@1|root,2ZUIM@2|Bacteria,1V47V@1239|Firmicutes,24HN9@186801|Clostridia,3Y0J3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
HGCANGJP_02578	457412.RSAG_02004	1.39e-195	543.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGWZ@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_02579	457412.RSAG_02005	5.12e-75	225.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJYT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
HGCANGJP_02580	1121115.AXVN01000074_gene2291	3.48e-213	588.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,3Y02V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
HGCANGJP_02581	1121115.AXVN01000074_gene2290	2.69e-187	521.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3XYTK@572511|Blautia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
HGCANGJP_02582	457412.RSAG_02014	2.59e-143	405.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
HGCANGJP_02583	457412.RSAG_02015	0.0	880.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
HGCANGJP_02584	457412.RSAG_01670	2.61e-133	377.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
HGCANGJP_02585	1121115.AXVN01000014_gene1248	0.0	1115.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3Y14F@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
HGCANGJP_02586	1121115.AXVN01000014_gene1247	5.21e-138	391.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3Y0XR@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
HGCANGJP_02587	1121115.AXVN01000014_gene1246	2.32e-194	539.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,3Y0ZA@572511|Blautia	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
HGCANGJP_02589	457412.RSAG_01674	3.72e-268	731.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3WP2Y@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
HGCANGJP_02590	457412.RSAG_01675	1.35e-211	585.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HGCANGJP_02591	1121115.AXVN01000014_gene1243	6.3e-224	618.0	2BADS@1|root,323U8@2|Bacteria,1VTZ8@1239|Firmicutes,24ZP1@186801|Clostridia,3Y1JU@572511|Blautia	186801|Clostridia	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02592	457412.RSAG_01677	4.05e-93	273.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3WKS1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
HGCANGJP_02593	1121115.AXVN01000014_gene1241	5.25e-282	769.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,3Y0AK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
HGCANGJP_02594	935948.KE386494_gene695	6.54e-207	602.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
HGCANGJP_02595	1345697.M493_09710	3.32e-227	656.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1WEKS@129337|Geobacillus	91061|Bacilli	G	Fibronectin type III-like domain	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_02596	1321778.HMPREF1982_00900	1.8e-142	414.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,267VT@186813|unclassified Clostridiales	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
HGCANGJP_02597	1391647.AVSV01000003_gene1453	1.64e-225	637.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
HGCANGJP_02598	941824.TCEL_02096	5.78e-89	278.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,36DIE@31979|Clostridiaceae	186801|Clostridia	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
HGCANGJP_02599	1235800.C819_00746	3.64e-31	133.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,27IA2@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_02600	553973.CLOHYLEM_05759	2.69e-104	317.0	COG2972@1|root,COG2972@2|Bacteria,1TRKI@1239|Firmicutes,24B7C@186801|Clostridia,21XPV@1506553|Lachnoclostridium	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
HGCANGJP_02601	1195236.CTER_4128	7.57e-112	350.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TV2J@1239|Firmicutes,249HW@186801|Clostridia,3WHT0@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
HGCANGJP_02602	457412.RSAG_01679	8.45e-202	558.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,3WHMV@541000|Ruminococcaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
HGCANGJP_02603	1121115.AXVN01000014_gene1239	1.44e-228	634.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,3XYJ1@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
HGCANGJP_02604	457412.RSAG_01681	1.91e-108	312.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HGCANGJP_02605	457412.RSAG_01682	1.06e-105	305.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
HGCANGJP_02606	1121115.AXVN01000119_gene3271	0.0	1082.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
HGCANGJP_02607	1121115.AXVN01000119_gene3272	5.43e-35	119.0	2BJ3C@1|root,32DC9@2|Bacteria,1V88B@1239|Firmicutes,25A9I@186801|Clostridia,3Y20E@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02608	1121115.AXVN01000119_gene3273	5.51e-140	395.0	COG0454@1|root,COG0456@2|Bacteria,1UHW4@1239|Firmicutes,24I24@186801|Clostridia,3Y1FU@572511|Blautia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02609	411463.EUBVEN_00921	3.94e-21	83.2	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,25XQP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02610	411463.EUBVEN_00922	5.96e-194	560.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia,25V2H@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
HGCANGJP_02611	411469.EUBHAL_02118	1.03e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,25VEQ@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_02612	457412.RSAG_01813	1.76e-153	431.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02613	585394.RHOM_13340	3.95e-251	689.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
HGCANGJP_02614	411469.EUBHAL_02115	9.36e-275	752.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,25WPZ@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_02615	411469.EUBHAL_02113	4.08e-160	449.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25YCG@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_02616	585394.RHOM_13355	5.85e-225	619.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
HGCANGJP_02617	585394.RHOM_13360	2.82e-83	246.0	28ZZK@1|root,2ZMPX@2|Bacteria,1V41I@1239|Firmicutes,24RFQ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02618	585394.RHOM_13365	6.88e-170	474.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HGCANGJP_02619	585394.RHOM_13370	1.07e-201	558.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
HGCANGJP_02620	411463.EUBVEN_00933	1.03e-33	117.0	2E6BP@1|root,330ZG@2|Bacteria,1VEZW@1239|Firmicutes,24MZZ@186801|Clostridia,25X3J@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
HGCANGJP_02621	585394.RHOM_13380	0.0	1099.0	COG0507@1|root,COG0507@2|Bacteria,1VQWC@1239|Firmicutes,250PW@186801|Clostridia	186801|Clostridia	L	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HGCANGJP_02622	585394.RHOM_13385	0.0	2638.0	COG1373@1|root,COG1373@2|Bacteria,1UMA8@1239|Firmicutes,25GDC@186801|Clostridia	186801|Clostridia	S	ATPase (AAA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02623	552396.HMPREF0863_01518	3.47e-73	220.0	2C5R4@1|root,2ZRGD@2|Bacteria,1V4WH@1239|Firmicutes	1239|Firmicutes	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_02624	457412.RSAG_01824	0.0	1087.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WGD4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
HGCANGJP_02625	1121115.AXVN01000080_gene890	4.84e-229	630.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,3XZA2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
HGCANGJP_02626	457412.RSAG_01826	7.33e-289	790.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia,3WJ2P@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
HGCANGJP_02628	1121115.AXVN01000052_gene887	0.0	1442.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
HGCANGJP_02629	457412.RSAG_01828	6.64e-170	474.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WGB8@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_02630	1121115.AXVN01000052_gene885	0.0	912.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZ8I@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
HGCANGJP_02631	457412.RSAG_01830	0.0	1145.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3WGIC@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
HGCANGJP_02632	457412.RSAG_01831	0.0	1350.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
HGCANGJP_02633	1121115.AXVN01000052_gene882	5.18e-134	379.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3XZUQ@572511|Blautia	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
HGCANGJP_02634	1121115.AXVN01000052_gene881	1.94e-120	343.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3XYZI@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
HGCANGJP_02635	1121115.AXVN01000052_gene880	2.42e-132	376.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,3XZIN@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
HGCANGJP_02636	1121115.AXVN01000052_gene879	2.09e-10	55.5	28U02@1|root,2ZG6F@2|Bacteria,1W5KD@1239|Firmicutes,2551S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02637	1121115.AXVN01000052_gene878	0.0	1127.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3XZA6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
HGCANGJP_02638	1121115.AXVN01000052_gene877	2.71e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0HD@572511|Blautia	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HGCANGJP_02639	457412.RSAG_01838	1.24e-204	567.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WIBR@541000|Ruminococcaceae	186801|Clostridia	C	pyridine	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
HGCANGJP_02640	1121115.AXVN01000052_gene875	1.29e-298	814.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3XYZQ@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
HGCANGJP_02641	457412.RSAG_01840	2.98e-246	677.0	2BP77@1|root,32HYI@2|Bacteria,1V84J@1239|Firmicutes,24JDS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02642	1121115.AXVN01000052_gene873	0.0	1420.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XZXF@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
HGCANGJP_02643	1121115.AXVN01000052_gene872	0.0	1000.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRXY@1239|Firmicutes,24BYW@186801|Clostridia,3Y1D5@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
HGCANGJP_02644	1121115.AXVN01000052_gene871	0.0	1115.0	COG2972@1|root,COG2972@2|Bacteria,1UYIY@1239|Firmicutes,24ACA@186801|Clostridia,3Y1EM@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
HGCANGJP_02645	1121115.AXVN01000052_gene870	3.39e-192	534.0	COG0395@1|root,COG0395@2|Bacteria,1TRD1@1239|Firmicutes,24BQQ@186801|Clostridia,3Y16U@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HGCANGJP_02646	457412.RSAG_01845	1.71e-210	582.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HGCANGJP_02647	457412.RSAG_01846	0.0	890.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia,3WHJ4@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02648	1121115.AXVN01000052_gene867	8.28e-295	803.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,3XZHU@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
HGCANGJP_02650	457412.RSAG_01848	1.95e-316	861.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WH4H@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
HGCANGJP_02651	1121115.AXVN01000177_gene3485	6.73e-266	729.0	COG3584@1|root,COG3584@2|Bacteria,1UVF9@1239|Firmicutes,25AFQ@186801|Clostridia,3XZV0@572511|Blautia	186801|Clostridia	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
HGCANGJP_02652	1121115.AXVN01000047_gene1270	1.1e-48	155.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24TZY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02654	1121115.AXVN01000047_gene1269	1.13e-292	798.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
HGCANGJP_02655	1121115.AXVN01000047_gene1268	4e-173	482.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
HGCANGJP_02656	457412.RSAG_01854	1.12e-183	512.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,3WIZ0@541000|Ruminococcaceae	186801|Clostridia	M	Ami_2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
HGCANGJP_02657	1121115.AXVN01000047_gene1266	0.0	932.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
HGCANGJP_02658	1121115.AXVN01000047_gene1265	5.98e-111	319.0	2E823@1|root,332G5@2|Bacteria,1V8A8@1239|Firmicutes,24NHT@186801|Clostridia,3Y088@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02659	1121115.AXVN01000047_gene1264	0.0	983.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
HGCANGJP_02660	1121115.AXVN01000047_gene1263	7.18e-57	177.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
HGCANGJP_02661	1121115.AXVN01000047_gene1262	1.67e-177	495.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,3XYZ9@572511|Blautia	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
HGCANGJP_02662	457412.RSAG_01860	0.0	1329.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
HGCANGJP_02663	1121115.AXVN01000047_gene1260	6.55e-222	611.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3XYUB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
HGCANGJP_02664	457412.RSAG_01862	0.0	1006.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
HGCANGJP_02665	1121115.AXVN01000047_gene1258	1.52e-43	141.0	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,3Y0RB@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HGCANGJP_02666	1121115.AXVN01000047_gene1257	2.56e-96	285.0	COG1033@1|root,COG1033@2|Bacteria,1VTBG@1239|Firmicutes,24YPV@186801|Clostridia,3Y1R8@572511|Blautia	186801|Clostridia	S	growth of symbiont in host cell	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02667	1121115.AXVN01000047_gene1256	0.0	964.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3XYNA@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
HGCANGJP_02668	1121115.AXVN01000047_gene1255	0.0	1313.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3XZC9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
HGCANGJP_02669	457412.RSAG_01868	0.0	2948.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
HGCANGJP_02670	1121115.AXVN01000047_gene1253	6.51e-247	678.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3XYGT@572511|Blautia	186801|Clostridia	H	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
HGCANGJP_02671	457412.RSAG_01870	1.05e-253	698.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
HGCANGJP_02672	1121115.AXVN01000047_gene1251	4.07e-265	731.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3XZ35@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
HGCANGJP_02673	1121115.AXVN01000047_gene1250	6.59e-256	700.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
HGCANGJP_02674	457412.RSAG_01873	1.95e-114	328.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,3WJ8H@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
HGCANGJP_02675	457412.RSAG_01874	8.89e-213	586.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,3WHH9@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
HGCANGJP_02676	457412.RSAG_01875	5.28e-236	648.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
HGCANGJP_02678	457412.RSAG_01877	1.14e-296	809.0	COG1277@1|root,COG1277@2|Bacteria,1UTUG@1239|Firmicutes,25EAK@186801|Clostridia,3WMG3@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
HGCANGJP_02679	457412.RSAG_01878	1.11e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3WHDX@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_02680	457412.RSAG_01879	1e-171	480.0	2DMFS@1|root,32R85@2|Bacteria,1U024@1239|Firmicutes,25MSI@186801|Clostridia,3WQUD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02681	457412.RSAG_01880	2.52e-119	341.0	COG1595@1|root,COG1595@2|Bacteria,1VBJI@1239|Firmicutes,24NKR@186801|Clostridia,3WS7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_02682	457412.RSAG_01882	0.0	1144.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
HGCANGJP_02683	457412.RSAG_01883	3.03e-139	400.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HGCANGJP_02684	457412.RSAG_01883	2.05e-86	262.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
HGCANGJP_02685	457412.RSAG_01884	0.0	1170.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
HGCANGJP_02686	457412.RSAG_01885	1.29e-231	636.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1UVPR@1239|Firmicutes,25KKF@186801|Clostridia,3WPZY@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_02687	457412.RSAG_01886	4.24e-310	843.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02688	457412.RSAG_01887	9.51e-295	801.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,3WHHT@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
HGCANGJP_02689	457412.RSAG_01888	1.14e-196	546.0	COG0395@1|root,COG0395@2|Bacteria,1TSJ9@1239|Firmicutes,24ERB@186801|Clostridia	186801|Clostridia	P	abc transporter permease protein	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_02690	457412.RSAG_01889	8.47e-207	572.0	COG1175@1|root,COG1175@2|Bacteria,1UXJV@1239|Firmicutes,25MIZ@186801|Clostridia,3WQ0J@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02691	457412.RSAG_01890	4.53e-303	825.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
HGCANGJP_02692	1121115.AXVN01000085_gene2190	2.63e-82	252.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes,24B0H@186801|Clostridia	186801|Clostridia	T	HAMP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
HGCANGJP_02693	457412.RSAG_01891	2.47e-249	695.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes,24B0H@186801|Clostridia	186801|Clostridia	T	HAMP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
HGCANGJP_02694	457412.RSAG_01892	0.0	1050.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TR4U@1239|Firmicutes,24JVF@186801|Clostridia,3WJ1J@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
HGCANGJP_02695	1121115.AXVN01000156_gene544	2.86e-177	495.0	COG4822@1|root,COG4822@2|Bacteria	2|Bacteria	H	anaerobic cobalamin biosynthetic process	cbiK	-	4.99.1.3	ko:K02006,ko:K02190	ko00860,ko01100,ko02010,map00860,map01100,map02010	M00245,M00246	R05807	RC01012	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran,CbiK,TP_methylase
HGCANGJP_02696	1121115.AXVN01000156_gene545	1.71e-111	321.0	COG5652@1|root,COG5652@2|Bacteria,1V72A@1239|Firmicutes,259NP@186801|Clostridia,3Y02J@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
HGCANGJP_02697	1121115.AXVN01000156_gene546	4.39e-96	281.0	2979U@1|root,2ZUHG@2|Bacteria,1W35F@1239|Firmicutes,256C8@186801|Clostridia,3Y0TR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02698	457412.RSAG_01896	2.68e-272	747.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
HGCANGJP_02699	457412.RSAG_02942	0.0	870.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
HGCANGJP_02700	457412.RSAG_02941	1.61e-48	154.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,3WKEN@541000|Ruminococcaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
HGCANGJP_02701	457412.RSAG_02940	7.55e-286	780.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3WGMK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
HGCANGJP_02702	1121115.AXVN01000035_gene3840	7.12e-275	752.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XYUM@572511|Blautia	186801|Clostridia	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
HGCANGJP_02703	457412.RSAG_02938	4.44e-171	478.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
HGCANGJP_02704	1121115.AXVN01000035_gene3842	3.51e-223	615.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3XZAN@572511|Blautia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
HGCANGJP_02705	457412.RSAG_02936	1.51e-177	493.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,3WJNZ@541000|Ruminococcaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
HGCANGJP_02706	1121115.AXVN01000035_gene3844	5.15e-269	738.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3XYJ6@572511|Blautia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
HGCANGJP_02707	1121115.AXVN01000035_gene3845	0.0	1172.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
HGCANGJP_02708	1121115.AXVN01000035_gene3846	2.55e-135	385.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3XZX7@572511|Blautia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
HGCANGJP_02709	1121115.AXVN01000035_gene3847	5.24e-235	648.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3XYPX@572511|Blautia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
HGCANGJP_02710	457412.RSAG_02931	0.0	1271.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3WGH5@541000|Ruminococcaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
HGCANGJP_02711	411459.RUMOBE_02569	0.0	1092.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3Y102@572511|Blautia	186801|Clostridia	T	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3,dCache_1
HGCANGJP_02712	457412.RSAG_02930	0.0	1691.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3WSS0@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg,SBP_bac_3,dCache_1
HGCANGJP_02713	1121115.AXVN01000035_gene3855	8.2e-68	205.0	COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,25CR8@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
HGCANGJP_02714	1121115.AXVN01000035_gene3856	1.45e-104	306.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia,3Y0AR@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
HGCANGJP_02715	1121115.AXVN01000035_gene3857	4.64e-169	475.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,3Y0E5@572511|Blautia	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
HGCANGJP_02716	411459.RUMOBE_01989	0.0	1031.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3XZ52@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HGCANGJP_02717	411459.RUMOBE_01990	7.87e-165	463.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3XYJP@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_02718	1121115.AXVN01000081_gene3055	4.25e-97	287.0	COG3279@1|root,COG3279@2|Bacteria,1VBY3@1239|Firmicutes,24GY2@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_02719	457412.RSAG_00455	3.45e-145	410.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3WIM2@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_02720	397290.C810_01994	7.04e-103	308.0	2EEYR@1|root,338S0@2|Bacteria,1VG5B@1239|Firmicutes,25DXF@186801|Clostridia,27MRS@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02721	1121115.AXVN01000095_gene452	5e-48	167.0	2DS65@1|root,33ER2@2|Bacteria,1VKAP@1239|Firmicutes,24UXI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02722	1121115.AXVN01000095_gene453	2.71e-89	278.0	2E29B@1|root,32XF1@2|Bacteria,1VQT6@1239|Firmicutes,24QIB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02723	1121115.AXVN01000206_gene3748	3.62e-117	342.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia,3Y1U0@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_02724	1121115.AXVN01000081_gene3054	4.49e-271	749.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3XZGY@572511|Blautia	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
HGCANGJP_02725	1121115.AXVN01000081_gene3053	1.13e-171	480.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,3XZ2M@572511|Blautia	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
HGCANGJP_02727	457412.RSAG_01754	1.87e-291	795.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3WGZH@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
HGCANGJP_02728	1121115.AXVN01000081_gene3051	0.0	949.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3XYNN@572511|Blautia	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
HGCANGJP_02729	1121115.AXVN01000081_gene3050	4.33e-242	668.0	COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
HGCANGJP_02730	1121115.AXVN01000081_gene3049	2.02e-222	614.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3XZJF@572511|Blautia	186801|Clostridia	P	COG COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HGCANGJP_02731	1121115.AXVN01000081_gene3048	0.0	973.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
HGCANGJP_02732	457412.RSAG_01759	2.59e-229	632.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3WNJT@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HGCANGJP_02733	1121115.AXVN01000081_gene3046	1.67e-225	622.0	COG1879@1|root,COG1879@2|Bacteria,1TPWA@1239|Firmicutes,25PX0@186801|Clostridia,3XYI7@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
HGCANGJP_02734	1121115.AXVN01000081_gene3045	0.0	1142.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
HGCANGJP_02735	457412.RSAG_01762	0.0	1038.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3WJ5A@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
HGCANGJP_02736	457412.RSAG_03510	2.27e-103	298.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,24FU7@186801|Clostridia,3WJ3H@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the RbsD FucU family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
HGCANGJP_02737	1121115.AXVN01000081_gene3042	0.0	1232.0	COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3XZ8N@572511|Blautia	186801|Clostridia	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
HGCANGJP_02738	1121115.AXVN01000001_gene1065	0.0	1145.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3XZD2@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
HGCANGJP_02739	1121115.AXVN01000001_gene1066	0.0	1027.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYSE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
HGCANGJP_02740	1121115.AXVN01000001_gene1067	6.6e-311	849.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZAY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_02741	1121115.AXVN01000001_gene1068	0.0	1652.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3XZ20@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
HGCANGJP_02742	457412.RSAG_01090	0.0	1374.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae	186801|Clostridia	J	translation elongation	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HGCANGJP_02743	1121115.AXVN01000001_gene1070	5.93e-261	715.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3XZI7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
HGCANGJP_02744	457412.RSAG_01092	5.95e-301	821.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
HGCANGJP_02745	1121115.AXVN01000001_gene1072	4.01e-235	647.0	COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,3XZ54@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,PTS-HPr
HGCANGJP_02746	457412.RSAG_01094	5.39e-42	141.0	2F54G@1|root,33XRK@2|Bacteria,1VVDU@1239|Firmicutes,250QM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02747	1121115.AXVN01000001_gene1074	1.28e-131	373.0	COG0655@1|root,COG0655@2|Bacteria,1TQKC@1239|Firmicutes,24H9P@186801|Clostridia,3Y053@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HGCANGJP_02748	1121115.AXVN01000001_gene1075	3.16e-285	783.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,3XZ2C@572511|Blautia	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
HGCANGJP_02749	1121115.AXVN01000001_gene1076	1.72e-251	689.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3XZ7B@572511|Blautia	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
HGCANGJP_02750	1121115.AXVN01000001_gene1077	9.06e-182	505.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3XYT2@572511|Blautia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
HGCANGJP_02751	457412.RSAG_01192	1.08e-113	326.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WIMH@541000|Ruminococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
HGCANGJP_02752	1121115.AXVN01000001_gene1079	3.47e-40	133.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3Y0D4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
HGCANGJP_02753	1121115.AXVN01000001_gene1080	1.77e-51	162.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3Y0EA@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
HGCANGJP_02754	1121115.AXVN01000001_gene1081	4.29e-310	847.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3XZA0@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
HGCANGJP_02755	1121115.AXVN01000001_gene1082	1.92e-67	204.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3Y0C3@572511|Blautia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
HGCANGJP_02756	1121115.AXVN01000001_gene1084	1.23e-33	115.0	COG1893@1|root,COG1893@2|Bacteria,1UVFC@1239|Firmicutes,25KH8@186801|Clostridia,3Y210@572511|Blautia	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02757	457412.RSAG_01987	7.17e-232	637.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3WSRR@541000|Ruminococcaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
HGCANGJP_02758	1121115.AXVN01000066_gene3236	3.23e-271	741.0	COG2334@1|root,COG2334@2|Bacteria,1UXS1@1239|Firmicutes,25MC4@186801|Clostridia,3XZ7J@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	APH
HGCANGJP_02759	457412.RSAG_01985	8.3e-253	692.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3WGSG@541000|Ruminococcaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
HGCANGJP_02760	457412.RSAG_01984	2.08e-200	554.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,3WJDK@541000|Ruminococcaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	nit	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
HGCANGJP_02761	1121115.AXVN01000066_gene3232	3.02e-178	496.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3XZZF@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
HGCANGJP_02762	1121115.AXVN01000066_gene3231	0.0	971.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3XYIV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
HGCANGJP_02763	1121115.AXVN01000066_gene3230	0.0	1251.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYZH@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HGCANGJP_02764	1121115.AXVN01000066_gene3229	0.0	1206.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3XZ8C@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
HGCANGJP_02765	1121115.AXVN01000066_gene3228	4.97e-220	607.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3XZ5K@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
HGCANGJP_02766	1121115.AXVN01000066_gene3227	1.18e-224	619.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3XYHF@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
HGCANGJP_02767	457412.RSAG_01977	0.0	1583.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,3WSNS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
HGCANGJP_02768	457412.RSAG_01976	8.73e-154	432.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
HGCANGJP_02769	1121115.AXVN01000066_gene3224	9.9e-126	357.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
HGCANGJP_02770	1121115.AXVN01000066_gene3223	1.05e-102	296.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3Y003@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
HGCANGJP_02771	457412.RSAG_01973	2.76e-162	455.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
HGCANGJP_02772	457412.RSAG_01972	6.29e-100	290.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
HGCANGJP_02773	1121115.AXVN01000066_gene3220	1.62e-225	620.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3XZ6W@572511|Blautia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HGCANGJP_02774	1121115.AXVN01000066_gene3219	1.12e-246	677.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3XYPY@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
HGCANGJP_02775	1121115.AXVN01000066_gene3218	8.06e-165	461.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,3XZ8R@572511|Blautia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
HGCANGJP_02778	1121115.AXVN01000012_gene3117	0.0	1058.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3Y0TG@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HGCANGJP_02779	1121115.AXVN01000012_gene3116	2.87e-61	187.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24QSZ@186801|Clostridia,3Y27B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02780	1121115.AXVN01000012_gene3115	0.0	1288.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y14N@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
HGCANGJP_02781	457412.RSAG_02749	6.36e-230	632.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3WN40@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
HGCANGJP_02782	1121115.AXVN01000012_gene3113	5.13e-246	673.0	COG3940@1|root,COG3940@2|Bacteria,1TRHI@1239|Firmicutes,24AG6@186801|Clostridia,3Y1H0@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
HGCANGJP_02783	1121115.AXVN01000012_gene3112	0.0	1068.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia	186801|Clostridia	G	family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
HGCANGJP_02784	1121115.AXVN01000012_gene3111	5.62e-224	617.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3Y1E9@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
HGCANGJP_02785	1121115.AXVN01000012_gene3110	0.0	928.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia,3Y14C@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02786	1121115.AXVN01000012_gene3109	1.25e-207	575.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
HGCANGJP_02787	1121115.AXVN01000012_gene3108	1.25e-203	564.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
HGCANGJP_02788	1121115.AXVN01000012_gene3107	0.0	1034.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
HGCANGJP_02789	1121115.AXVN01000012_gene3106	8.74e-196	543.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,3XZRH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HGCANGJP_02790	457412.RSAG_02745	5.44e-176	490.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WH3N@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
HGCANGJP_02791	457412.RSAG_02744	8.82e-265	725.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3WH26@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HGCANGJP_02792	1121115.AXVN01000012_gene3103	2.04e-160	450.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3XZHW@572511|Blautia	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
HGCANGJP_02793	457412.RSAG_02735	1.51e-180	501.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia,3WI6A@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
HGCANGJP_02794	1121115.AXVN01000012_gene3092	4.14e-196	556.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3XZ6F@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
HGCANGJP_02795	1121115.AXVN01000012_gene3091	7.54e-40	132.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HGCANGJP_02796	1121115.AXVN01000012_gene3090	1.05e-179	501.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
HGCANGJP_02797	457412.RSAG_01651	8.45e-238	654.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3WGMZ@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
HGCANGJP_02798	1121115.AXVN01000018_gene17	6.1e-160	448.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
HGCANGJP_02799	1121115.AXVN01000018_gene16	3.14e-89	262.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3XZUC@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
HGCANGJP_02800	1121115.AXVN01000018_gene15	3.32e-119	340.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3XZ8Y@572511|Blautia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
HGCANGJP_02801	1121115.AXVN01000018_gene14	1.44e-38	129.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia,3Y0SS@572511|Blautia	186801|Clostridia	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
HGCANGJP_02802	1121115.AXVN01000018_gene13	7.29e-46	147.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,3Y0JI@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
HGCANGJP_02803	1121115.AXVN01000121_gene2849	2.41e-178	496.0	COG1028@1|root,COG1028@2|Bacteria,1V2KA@1239|Firmicutes,24GZZ@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
HGCANGJP_02804	1121115.AXVN01000121_gene2848	0.0	1172.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
HGCANGJP_02805	457412.RSAG_01659	1.2e-283	774.0	COG3475@1|root,COG3475@2|Bacteria	2|Bacteria	M	LICD family	licD	-	-	ko:K02011,ko:K07271,ko:K19872	ko00515,ko01100,ko02010,map00515,map01100,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko04131	3.A.1.10	-	-	LicD
HGCANGJP_02806	457412.RSAG_01660	0.0	1524.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,3WKER@541000|Ruminococcaceae	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
HGCANGJP_02807	457412.RSAG_01661	9.56e-317	863.0	COG0615@1|root,COG0673@1|root,COG0615@2|Bacteria,COG0673@2|Bacteria,1V3KY@1239|Firmicutes,24BKY@186801|Clostridia,3WIHC@541000|Ruminococcaceae	186801|Clostridia	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GFO_IDH_MocA
HGCANGJP_02808	457412.RSAG_03495	1.39e-313	855.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	ko:K13663	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
HGCANGJP_02809	1121115.AXVN01000147_gene3491	4.83e-183	509.0	COG0463@1|root,COG0463@2|Bacteria,1TSPS@1239|Firmicutes,25FHJ@186801|Clostridia,3Y1C1@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
HGCANGJP_02810	1121115.AXVN01000147_gene3490	0.0	923.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3XZJ0@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
HGCANGJP_02811	457412.RSAG_01664	1.93e-249	687.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HGCANGJP_02812	457412.RSAG_01665	4.03e-263	721.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
HGCANGJP_02813	457412.RSAG_01666	1.06e-126	362.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WJUS@541000|Ruminococcaceae	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
HGCANGJP_02814	457412.RSAG_01667	0.0	1008.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3WM6D@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
HGCANGJP_02815	1121115.AXVN01000164_gene904	1.39e-142	403.0	COG5012@1|root,COG5012@2|Bacteria,1VSJU@1239|Firmicutes,24XK2@186801|Clostridia,3Y145@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
HGCANGJP_02816	457412.RSAG_01691	1.78e-283	775.0	COG0526@1|root,COG0526@2|Bacteria,1TSFN@1239|Firmicutes,24DAS@186801|Clostridia	186801|Clostridia	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
HGCANGJP_02817	1121115.AXVN01000014_gene1194	3.95e-34	116.0	2AQUU@1|root,31G2Z@2|Bacteria,1UDXX@1239|Firmicutes,25IS7@186801|Clostridia,3Y251@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02818	457412.RSAG_01689	1.2e-207	575.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WI0F@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
HGCANGJP_02819	1121115.AXVN01000014_gene1196	1.33e-204	568.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia,3Y09S@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_02820	1121115.AXVN01000014_gene1197	9.17e-116	332.0	2BXQ3@1|root,2ZCWE@2|Bacteria,1V3E8@1239|Firmicutes,24GTI@186801|Clostridia,3Y1HF@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02821	457412.RSAG_01686	0.0	863.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3WMKQ@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
HGCANGJP_02822	457412.RSAG_01685	2.16e-208	577.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3WIYD@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
HGCANGJP_02823	457412.RSAG_01684	5.9e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,3WJKJ@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
HGCANGJP_02824	457412.RSAG_01683	0.0	2033.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WSRP@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
HGCANGJP_02825	1121115.AXVN01000014_gene1225	3.86e-299	816.0	COG1653@1|root,COG1653@2|Bacteria,1VR2M@1239|Firmicutes,24YJT@186801|Clostridia,3Y1T3@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
HGCANGJP_02826	1121115.AXVN01000014_gene1226	1.77e-184	515.0	COG1175@1|root,COG1175@2|Bacteria,1VT09@1239|Firmicutes,24YP4@186801|Clostridia,3Y1PN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02827	1235792.C808_04006	1.47e-137	395.0	COG0395@1|root,COG0395@2|Bacteria,1VQXI@1239|Firmicutes,24ECS@186801|Clostridia,27N2Y@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
HGCANGJP_02828	1121115.AXVN01000014_gene1228	4.55e-206	569.0	COG0491@1|root,COG0491@2|Bacteria,1V3ZB@1239|Firmicutes,25BG4@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
HGCANGJP_02829	1121115.AXVN01000014_gene1229	0.0	1043.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
HGCANGJP_02830	1121115.AXVN01000014_gene1230	0.0	1021.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VSN8@1239|Firmicutes,24YS7@186801|Clostridia,3Y1SB@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
HGCANGJP_02831	1121115.AXVN01000014_gene1231	8.57e-306	835.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,258AG@186801|Clostridia,3Y0AF@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
HGCANGJP_02832	518637.EUBIFOR_00452	2.55e-27	108.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,3VQ1Q@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14
HGCANGJP_02833	457412.RSAG_01929	6.92e-215	595.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02834	457412.RSAG_01928	5.5e-284	775.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
HGCANGJP_02835	457412.RSAG_01927	1.41e-114	328.0	COG1418@1|root,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,3WJN7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HD
HGCANGJP_02836	457412.RSAG_01925	6.2e-135	382.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WK21@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_02837	1121115.AXVN01000078_gene2825	0.0	1105.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3Y0RS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
HGCANGJP_02838	457412.RSAG_01923	2.79e-275	753.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3WG9F@541000|Ruminococcaceae	186801|Clostridia	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
HGCANGJP_02839	457412.RSAG_01922	3.99e-134	381.0	COG4720@1|root,COG4720@2|Bacteria,1USKD@1239|Firmicutes,24A2K@186801|Clostridia,3WKAY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
HGCANGJP_02840	411473.RUMCAL_00434	3.38e-254	713.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,5.4.99.16	ko:K01176,ko:K05343	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
HGCANGJP_02841	457412.RSAG_01921	1.22e-310	846.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
HGCANGJP_02842	457412.RSAG_01920	2.39e-233	644.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3WJ50@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HGCANGJP_02843	1121115.AXVN01000078_gene2830	2.49e-196	545.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3Y0BN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
HGCANGJP_02844	1121115.AXVN01000078_gene2831	0.0	903.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZQF@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_02845	1121115.AXVN01000078_gene2832	5.48e-212	587.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3XYZZ@572511|Blautia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
HGCANGJP_02846	457412.RSAG_01913	0.0	1332.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
HGCANGJP_02847	457412.RSAG_02193	5.11e-214	592.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
HGCANGJP_02848	457412.RSAG_02192	9.63e-306	836.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WGX2@541000|Ruminococcaceae	186801|Clostridia	S	xanthine uracil permease family protein K06901	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
HGCANGJP_02849	1121115.AXVN01000024_gene284	2.2e-313	853.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZ7R@572511|Blautia	186801|Clostridia	F	COG COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HGCANGJP_02850	457412.RSAG_02190	3.23e-238	659.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3WH44@541000|Ruminococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
HGCANGJP_02851	1121115.AXVN01000024_gene287	5.34e-81	240.0	2EC8D@1|root,3366W@2|Bacteria,1VEI1@1239|Firmicutes,24WC7@186801|Clostridia	186801|Clostridia	S	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
HGCANGJP_02852	1121115.AXVN01000024_gene288	2.07e-302	823.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
HGCANGJP_02853	457412.RSAG_02187	1.19e-256	702.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3WGZJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
HGCANGJP_02854	457412.RSAG_02186	5.54e-286	782.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
HGCANGJP_02855	1121115.AXVN01000024_gene291	2.17e-212	587.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3XZI8@572511|Blautia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
HGCANGJP_02856	1121115.AXVN01000024_gene292	8.91e-291	793.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
HGCANGJP_02857	1121115.AXVN01000024_gene293	2.98e-304	831.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3Y0QZ@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_02858	457412.RSAG_02182	1.14e-168	471.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia,3WHMG@541000|Ruminococcaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_02859	457412.RSAG_02181	4.04e-86	253.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes,24Q19@186801|Clostridia	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
HGCANGJP_02860	457412.RSAG_02180	0.0	1326.0	COG1520@1|root,COG1520@2|Bacteria,1UKI6@1239|Firmicutes,25FXQ@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02861	457412.RSAG_03057	1.65e-63	194.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02862	1121115.AXVN01000002_gene1446	0.0	1230.0	COG1680@1|root,COG1680@2|Bacteria,1W747@1239|Firmicutes,256Q7@186801|Clostridia,3Y0WX@572511|Blautia	2|Bacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
HGCANGJP_02863	457412.RSAG_00083	8.63e-310	844.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HGCANGJP_02864	1121115.AXVN01000002_gene1444	3.39e-265	731.0	COG4219@1|root,COG4219@2|Bacteria,1V0EY@1239|Firmicutes,24EI3@186801|Clostridia	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
HGCANGJP_02865	457412.RSAG_00081	3.63e-66	203.0	2FAVS@1|root,3432X@2|Bacteria,1VXAQ@1239|Firmicutes,2520G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02866	1121115.AXVN01000002_gene1442	6.19e-53	166.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HGCANGJP_02867	1121115.AXVN01000002_gene1441	1.4e-266	741.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,3Y15H@572511|Blautia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
HGCANGJP_02868	457412.RSAG_00077	0.0	1125.0	COG5492@1|root,COG5492@2|Bacteria,1UK32@1239|Firmicutes,25FHP@186801|Clostridia	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FIVAR,PBP-Tp47_a,PBP-Tp47_c
HGCANGJP_02869	457412.RSAG_00076	4.76e-246	676.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WGXU@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
HGCANGJP_02870	457412.RSAG_00075	4.87e-189	524.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WIWA@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
HGCANGJP_02871	457412.RSAG_00074	2.1e-94	280.0	COG3976@1|root,COG3976@2|Bacteria,1VT26@1239|Firmicutes,25BMN@186801|Clostridia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
HGCANGJP_02872	1121115.AXVN01000002_gene1436	0.0	1139.0	COG5492@1|root,COG5492@2|Bacteria,1UKHW@1239|Firmicutes,25FXE@186801|Clostridia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HGCANGJP_02873	457412.RSAG_00072	1.47e-94	277.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3WJDB@541000|Ruminococcaceae	186801|Clostridia	S	heptaprenyl diphosphate synthase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
HGCANGJP_02874	1121115.AXVN01000002_gene1434	3.01e-77	230.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3Y0CQ@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HGCANGJP_02875	457412.RSAG_00070	0.0	1170.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HGCANGJP_02876	457412.RSAG_00069	1.45e-46	149.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
HGCANGJP_02877	457412.RSAG_00068	5.41e-87	256.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WK31@541000|Ruminococcaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
HGCANGJP_02878	411459.RUMOBE_01991	1.48e-167	478.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,3XZVX@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K19081	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
HGCANGJP_02879	411459.RUMOBE_01992	1.49e-147	416.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,3XYPS@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	graR	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_02880	1121115.AXVN01000049_gene1298	7.7e-41	139.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,3XYHQ@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
HGCANGJP_02881	457412.RSAG_02924	3.68e-107	309.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
HGCANGJP_02882	457412.RSAG_02923	0.0	1238.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
HGCANGJP_02883	457412.RSAG_02922	9.94e-209	577.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,3WGR8@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
HGCANGJP_02884	1121115.AXVN01000049_gene1301	2.12e-273	749.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3XZBV@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
HGCANGJP_02885	457412.RSAG_02920	7.74e-203	563.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3WHNT@541000|Ruminococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
HGCANGJP_02886	457412.RSAG_02919	4.46e-156	438.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WGK4@541000|Ruminococcaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
HGCANGJP_02887	1121115.AXVN01000049_gene1304	1.19e-255	701.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3XYND@572511|Blautia	186801|Clostridia	QT	Psort location Cytoplasmic, score 8.87	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
HGCANGJP_02888	457412.RSAG_02917	1.06e-199	554.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HGCANGJP_02889	1121115.AXVN01000049_gene1306	1.54e-84	249.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,3Y0F4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
HGCANGJP_02890	1121115.AXVN01000049_gene1307	0.0	1144.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3XYVS@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	OPT
HGCANGJP_02891	457412.RSAG_02914	0.0	1171.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
HGCANGJP_02892	457412.RSAG_02913	7.61e-217	598.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3WH7J@541000|Ruminococcaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
HGCANGJP_02893	457412.RSAG_02912	0.0	1404.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
HGCANGJP_02894	457412.RSAG_02911	5.23e-229	630.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,3WHA2@541000|Ruminococcaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
HGCANGJP_02895	457412.RSAG_02909	6.7e-199	550.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HGCANGJP_02896	1121115.AXVN01000049_gene1313	3.01e-179	499.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3XYZ4@572511|Blautia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
HGCANGJP_02897	1121115.AXVN01000049_gene1314	8.17e-286	780.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3XYNP@572511|Blautia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
HGCANGJP_02898	1121115.AXVN01000049_gene1315	2.3e-145	410.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3Y006@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
HGCANGJP_02899	1121115.AXVN01000049_gene1316	2.86e-176	493.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3XYU5@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
HGCANGJP_02900	1121115.AXVN01000049_gene1317	3.01e-229	632.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3XZ38@572511|Blautia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
HGCANGJP_02901	1121115.AXVN01000049_gene1318	1.04e-130	371.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,3XZUJ@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
HGCANGJP_02902	457412.RSAG_02902	0.0	966.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WHMI@541000|Ruminococcaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
HGCANGJP_02903	1121115.AXVN01000049_gene1321	0.0	891.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
HGCANGJP_02904	457412.RSAG_02900	2.25e-55	175.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02909	1121115.AXVN01000084_gene1825	0.0	1847.0	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,1UVF4@1239|Firmicutes,25KH5@186801|Clostridia,3Y235@572511|Blautia	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HGCANGJP_02910	1121115.AXVN01000084_gene1826	1.36e-87	258.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,2502W@186801|Clostridia,3Y24M@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02911	1121115.AXVN01000084_gene1827	0.0	1223.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1V7U3@1239|Firmicutes,24G0F@186801|Clostridia,3Y202@572511|Blautia	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
HGCANGJP_02912	1121115.AXVN01000084_gene1828	4.75e-187	524.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3XZED@572511|Blautia	186801|Clostridia	M	COG COG1464 ABC-type metal ion transport system, periplasmic component surface antigen	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
HGCANGJP_02913	1121115.AXVN01000084_gene1829	2.63e-135	385.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3XYKJ@572511|Blautia	186801|Clostridia	P	COG COG2011 ABC-type metal ion transport system, permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
HGCANGJP_02914	1121115.AXVN01000084_gene1830	7.54e-242	665.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3XZSW@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
HGCANGJP_02915	679200.HMPREF9333_01225	1.45e-15	78.2	COG1690@1|root,COG1690@2|Bacteria,1TPJ2@1239|Firmicutes,2481V@186801|Clostridia	186801|Clostridia	S	Belongs to the RtcB family	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
HGCANGJP_02916	1280689.AUJC01000003_gene983	5.17e-15	74.3	COG5632@1|root,COG5632@2|Bacteria,1V7KT@1239|Firmicutes,24G8M@186801|Clostridia	186801|Clostridia	M	n-acetylmuramoyl-l-alanine amidase	ampD	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2,Cu_amine_oxidN1,DUF4214,Glucosaminidase,PG_binding_1,SH3_3,SPOR
HGCANGJP_02917	553973.CLOHYLEM_04450	1.82e-14	78.6	COG3409@1|root,COG3409@2|Bacteria,1UIRK@1239|Firmicutes,24KJ0@186801|Clostridia,223KP@1506553|Lachnoclostridium	186801|Clostridia	M	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1
HGCANGJP_02918	1121115.AXVN01000084_gene1833	1.23e-166	466.0	2EXDX@1|root,33QQG@2|Bacteria,1VTSR@1239|Firmicutes,24YUS@186801|Clostridia,3Y1G7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02919	457412.RSAG_00449	4.71e-261	736.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3WGJR@541000|Ruminococcaceae	186801|Clostridia	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
HGCANGJP_02920	1123075.AUDP01000020_gene1533	1.25e-101	324.0	COG3942@1|root,COG3942@2|Bacteria	2|Bacteria	S	pathogenesis	usp	-	3.5.1.28	ko:K21471,ko:K22409	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	CHAP,LysM
HGCANGJP_02922	457412.RSAG_02887	0.0	2498.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
HGCANGJP_02923	1121115.AXVN01000084_gene1835	2.49e-205	568.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZ9N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
HGCANGJP_02924	1121115.AXVN01000084_gene1836	1.4e-197	547.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3XYU0@572511|Blautia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
HGCANGJP_02925	1121115.AXVN01000046_gene2947	1.85e-71	215.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,3Y061@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
HGCANGJP_02926	1121115.AXVN01000046_gene2948	7.08e-49	155.0	2ES6S@1|root,33JRI@2|Bacteria,1VQGH@1239|Firmicutes,24WUX@186801|Clostridia,3Y0HU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02927	1121115.AXVN01000046_gene2949	4.41e-131	372.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,3XZCM@572511|Blautia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HGCANGJP_02928	1121115.AXVN01000046_gene2950	0.0	890.0	COG4213@1|root,COG4213@2|Bacteria,1VR5M@1239|Firmicutes,24ZY3@186801|Clostridia,3Y037@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
HGCANGJP_02929	1121115.AXVN01000046_gene2951	1.56e-134	382.0	COG2378@1|root,COG2378@2|Bacteria,1UH6Q@1239|Firmicutes,2504G@186801|Clostridia,3Y0EB@572511|Blautia	186801|Clostridia	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02930	457412.RSAG_02878	9.84e-180	499.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3WHHU@541000|Ruminococcaceae	186801|Clostridia	S	glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
HGCANGJP_02931	457412.RSAG_02877	0.0	896.0	COG0769@1|root,COG0769@2|Bacteria,1UHY9@1239|Firmicutes,25E6X@186801|Clostridia,3WHF5@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
HGCANGJP_02932	457412.RSAG_02876	3.23e-217	598.0	COG0584@1|root,COG0584@2|Bacteria,1TUUB@1239|Firmicutes,259V0@186801|Clostridia,3WQRJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02933	1121115.AXVN01000046_gene2955	1.28e-115	332.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3XZ2H@572511|Blautia	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
HGCANGJP_02934	457412.RSAG_02873	5.58e-221	610.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
HGCANGJP_02935	457412.RSAG_02872	5.13e-138	390.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
HGCANGJP_02936	1121115.AXVN01000046_gene2958	2.78e-85	251.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3XZVK@572511|Blautia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
HGCANGJP_02937	1121115.AXVN01000046_gene2959	2.1e-78	233.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3Y043@572511|Blautia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
HGCANGJP_02938	1121115.AXVN01000046_gene2961	4.86e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3Y0HJ@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
HGCANGJP_02939	1121115.AXVN01000046_gene2962	3.05e-184	511.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZ5M@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
HGCANGJP_02940	1121115.AXVN01000046_gene2963	4.7e-156	437.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
HGCANGJP_02941	457412.RSAG_02864	1.31e-302	827.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,3WG8Z@541000|Ruminococcaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
HGCANGJP_02942	1121115.AXVN01000046_gene2965	2.1e-94	276.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3XZUB@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
HGCANGJP_02943	1121115.AXVN01000046_gene2966	1.2e-33	115.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
HGCANGJP_02944	1121115.AXVN01000046_gene2967	1.46e-112	323.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
HGCANGJP_02945	1121115.AXVN01000046_gene2968	1.22e-77	231.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
HGCANGJP_02946	1121115.AXVN01000046_gene2969	1.21e-109	317.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3XYVK@572511|Blautia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
HGCANGJP_02947	1121115.AXVN01000046_gene2970	8.56e-90	263.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
HGCANGJP_02948	1121115.AXVN01000046_gene2971	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3Y0DU@572511|Blautia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
HGCANGJP_02949	457412.RSAG_02856	9.39e-123	350.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
HGCANGJP_02950	1121115.AXVN01000046_gene2973	2.29e-64	196.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
HGCANGJP_02951	1121115.AXVN01000046_gene2974	1.8e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3XZZG@572511|Blautia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
HGCANGJP_02952	457412.RSAG_02853	4.6e-53	166.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
HGCANGJP_02953	457412.RSAG_02852	1.39e-36	124.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
HGCANGJP_02954	1121115.AXVN01000046_gene2977	1.88e-101	293.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3XYIJ@572511|Blautia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
HGCANGJP_02955	1121115.AXVN01000046_gene2978	6.89e-151	424.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3XZ7Y@572511|Blautia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
HGCANGJP_02956	1121115.AXVN01000046_gene2979	5.64e-84	248.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
HGCANGJP_02957	1121115.AXVN01000046_gene2980	1.77e-61	188.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3Y09D@572511|Blautia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
HGCANGJP_02958	457412.RSAG_02847	3.72e-200	554.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
HGCANGJP_02959	1121115.AXVN01000046_gene2982	7.84e-61	187.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3Y06M@572511|Blautia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
HGCANGJP_02960	1121115.AXVN01000046_gene2983	4.85e-136	386.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
HGCANGJP_02961	1121115.AXVN01000046_gene2984	1.77e-149	420.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
HGCANGJP_02962	1121115.AXVN01000046_gene2985	3.91e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3XZZ4@572511|Blautia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
HGCANGJP_02963	1121115.AXVN01000046_gene2986	4.72e-235	651.0	COG0681@1|root,COG0681@2|Bacteria,1VGJ6@1239|Firmicutes,24SUY@186801|Clostridia,3Y28M@572511|Blautia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02964	1121115.AXVN01000046_gene2987	1.27e-50	160.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3Y2CC@572511|Blautia	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
HGCANGJP_02965	1121115.AXVN01000046_gene2988	3.83e-232	640.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3XYJH@572511|Blautia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
HGCANGJP_02966	457412.RSAG_02839	9.96e-212	585.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
HGCANGJP_02967	1121115.AXVN01000046_gene2990	1.03e-211	585.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3XZDE@572511|Blautia	186801|Clostridia	M	UDP-N-acetylenolpyruvoylglucosamine reductase	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
HGCANGJP_02968	1121115.AXVN01000057_gene2532	8.08e-100	289.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,3Y0C4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
HGCANGJP_02969	1121115.AXVN01000057_gene2531	2.93e-107	309.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3Y02E@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HGCANGJP_02970	457412.RSAG_02835	6.75e-270	737.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
HGCANGJP_02971	457412.RSAG_02834	2.69e-79	235.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
HGCANGJP_02972	1121115.AXVN01000057_gene2528	3.6e-146	411.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,3XZTN@572511|Blautia	186801|Clostridia	S	Psort location	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
HGCANGJP_02973	1121115.AXVN01000057_gene2527	3.47e-109	315.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3Y02K@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
HGCANGJP_02975	1121115.AXVN01000057_gene2526	4.08e-157	442.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,3XZEX@572511|Blautia	186801|Clostridia	K	COG COG1191 DNA-directed RNA polymerase specialized sigma subunit	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
HGCANGJP_02976	1121115.AXVN01000057_gene2525	3.68e-97	282.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3Y0A1@572511|Blautia	186801|Clostridia	H	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
HGCANGJP_02977	1121115.AXVN01000057_gene2524	2.76e-70	211.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3Y0KP@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
HGCANGJP_02978	457412.RSAG_02828	8.58e-268	739.0	COG0457@1|root,COG0457@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
HGCANGJP_02979	1121115.AXVN01000057_gene2522	3.2e-27	99.0	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,258G8@186801|Clostridia,3Y0SU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02980	457412.RSAG_02826	8.66e-316	859.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGW8@541000|Ruminococcaceae	186801|Clostridia	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
HGCANGJP_02981	457412.RSAG_02825	0.0	1352.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3WSDQ@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
HGCANGJP_02982	1121115.AXVN01000057_gene2519	0.0	1808.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
HGCANGJP_02983	1304866.K413DRAFT_2121	3.71e-195	548.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,36F05@31979|Clostridiaceae	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
HGCANGJP_02984	1304866.K413DRAFT_2120	4.22e-147	418.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24B66@186801|Clostridia,36W4B@31979|Clostridiaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
HGCANGJP_02985	742735.HMPREF9467_05079	5.1e-262	732.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,21ZXU@1506553|Lachnoclostridium	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
HGCANGJP_02986	411902.CLOBOL_01073	3.82e-185	520.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,21YV5@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG4608 ABC-type oligopeptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
HGCANGJP_02987	411902.CLOBOL_01072	6.12e-161	459.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,21XI0@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
HGCANGJP_02988	742735.HMPREF9467_05082	1e-147	423.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,21YVI@1506553|Lachnoclostridium	186801|Clostridia	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
HGCANGJP_02989	411902.CLOBOL_01070	2.32e-45	154.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,21XHD@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HGCANGJP_02990	1121115.AXVN01000002_gene1447	0.0	904.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XZ69@572511|Blautia	186801|Clostridia	H	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
HGCANGJP_02991	1121115.AXVN01000002_gene1448	7.15e-122	348.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3Y071@572511|Blautia	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
HGCANGJP_02992	457412.RSAG_00087	1.48e-251	692.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
HGCANGJP_02993	1121115.AXVN01000002_gene1450	1.12e-55	180.0	29V65@1|root,30GJT@2|Bacteria,1UG71@1239|Firmicutes,25NFM@186801|Clostridia,3Y24B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_02994	1121115.AXVN01000002_gene1451	0.0	1153.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3XZH5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
HGCANGJP_02995	1121115.AXVN01000002_gene1452	3.2e-83	246.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
HGCANGJP_02996	457412.RSAG_00093	0.0	911.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,3WPCY@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
HGCANGJP_02997	457412.RSAG_00094	0.0	1252.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HGCANGJP_02998	1121115.AXVN01000020_gene131	5.14e-165	462.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,3XZQP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
HGCANGJP_02999	457412.RSAG_00096	5.12e-285	779.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,3WICU@541000|Ruminococcaceae	186801|Clostridia	J	TIGRFAM ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
HGCANGJP_03000	1121115.AXVN01000020_gene129	3.99e-64	196.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3Y060@572511|Blautia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
HGCANGJP_03001	1121115.AXVN01000020_gene128	1.58e-70	212.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,25N63@186801|Clostridia,3Y0KN@572511|Blautia	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
HGCANGJP_03002	1121115.AXVN01000020_gene127	3.52e-62	190.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3Y06C@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
HGCANGJP_03003	1121115.AXVN01000020_gene126	1.74e-315	858.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3XYJQ@572511|Blautia	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
HGCANGJP_03004	1121115.AXVN01000020_gene125	6e-60	185.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3Y0BI@572511|Blautia	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
HGCANGJP_03005	1121115.AXVN01000020_gene124	6.2e-155	434.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,3XZHC@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HGCANGJP_03006	1121115.AXVN01000020_gene123	3.1e-143	403.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3XYUN@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
HGCANGJP_03007	1121115.AXVN01000020_gene122	1.23e-80	239.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3Y07Y@572511|Blautia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
HGCANGJP_03008	1121115.AXVN01000020_gene121	4.19e-146	411.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3XYNM@572511|Blautia	186801|Clostridia	L	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
HGCANGJP_03009	457412.RSAG_02518	0.0	1577.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia,3WH2C@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
HGCANGJP_03010	457412.RSAG_02517	3.05e-280	766.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V48A@1239|Firmicutes,24GUP@186801|Clostridia,3WRJR@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
HGCANGJP_03011	457412.RSAG_02516	0.0	1159.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24EC1@186801|Clostridia,3WNN0@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
HGCANGJP_03012	457412.RSAG_02515	0.0	890.0	COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate ABC transporter	-	-	-	ko:K10200	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	SBP_bac_8,TAT_signal
HGCANGJP_03013	457412.RSAG_02514	4.47e-198	550.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WI95@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10201	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
HGCANGJP_03014	1121115.AXVN01000060_gene478	6.33e-189	525.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZD4@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10202	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
HGCANGJP_03015	457412.RSAG_02512	0.0	1001.0	COG3669@1|root,COG3669@2|Bacteria,1TSG7@1239|Firmicutes,247VJ@186801|Clostridia,3WNXK@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,F5_F8_type_C,FIVAR,Gram_pos_anchor
HGCANGJP_03017	500632.CLONEX_03326	2.15e-06	48.5	COG0110@1|root,COG0110@2|Bacteria,1V06U@1239|Firmicutes,25BGT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
HGCANGJP_03018	1121115.AXVN01000060_gene474	6.15e-236	650.0	COG1609@1|root,COG1609@2|Bacteria,1TSU0@1239|Firmicutes,24C3S@186801|Clostridia,3XZBF@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HGCANGJP_03019	457412.RSAG_02509	4.41e-219	605.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,248XU@186801|Clostridia,3WHDQ@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
HGCANGJP_03020	1121115.AXVN01000060_gene471	3.2e-209	578.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,3XZ22@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
HGCANGJP_03021	1121115.AXVN01000060_gene470	0.0	1140.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,3XZ5C@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
HGCANGJP_03022	1121115.AXVN01000060_gene469	0.0	1025.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XYR0@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
HGCANGJP_03023	622312.ROSEINA2194_03252	3.49e-91	268.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
HGCANGJP_03024	411459.RUMOBE_01935	1.3e-40	134.0	2BCQI@1|root,326AY@2|Bacteria,1US91@1239|Firmicutes,25A84@186801|Clostridia,3Y22C@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03025	1121115.AXVN01000097_gene3800	4.98e-85	250.0	COG3304@1|root,COG3304@2|Bacteria,1VADH@1239|Firmicutes,24NFV@186801|Clostridia,3Y0CX@572511|Blautia	186801|Clostridia	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
HGCANGJP_03026	1121296.JONJ01000013_gene220	0.0	1362.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,21XJ9@1506553|Lachnoclostridium	186801|Clostridia	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
HGCANGJP_03027	457412.RSAG_01329	1.12e-90	265.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,25EBI@186801|Clostridia,3WISB@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HGCANGJP_03028	457412.RSAG_01328	2.02e-47	151.0	2EIT0@1|root,33CIB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03030	457412.RSAG_01326	2.09e-91	267.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,3WJAK@541000|Ruminococcaceae	186801|Clostridia	T	low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HGCANGJP_03031	411459.RUMOBE_01946	3.81e-13	63.2	2DGUU@1|root,2ZXCV@2|Bacteria,1W1ZP@1239|Firmicutes,256G9@186801|Clostridia,3Y25Q@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03032	457412.RSAG_01323	2.73e-92	270.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,3WJTP@541000|Ruminococcaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
HGCANGJP_03033	457412.RSAG_01322	2.76e-83	246.0	COG0346@1|root,COG0346@2|Bacteria,1V1Y9@1239|Firmicutes,24FQQ@186801|Clostridia,3WJC5@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
HGCANGJP_03034	457412.RSAG_01321	2.43e-100	291.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,3WJRQ@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
HGCANGJP_03035	1121115.AXVN01000114_gene1669	0.0	972.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia,3XZ9Z@572511|Blautia	186801|Clostridia	L	COG COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
HGCANGJP_03036	1121115.AXVN01000114_gene1670	2.42e-91	267.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,3Y0C1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03037	1121115.AXVN01000114_gene1671	5e-130	369.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,3XZBC@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
HGCANGJP_03038	457412.RSAG_01315	4.08e-117	335.0	COG1418@1|root,COG1418@2|Bacteria,1VBWP@1239|Firmicutes,24JJV@186801|Clostridia,3WJVP@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
HGCANGJP_03039	457412.RSAG_01314	2.61e-194	538.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WHB5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
HGCANGJP_03040	457412.RSAG_01313	6.7e-204	564.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,3WI4F@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
HGCANGJP_03041	1121115.AXVN01000114_gene1675	1.45e-76	228.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia,3Y09F@572511|Blautia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
HGCANGJP_03042	1121115.AXVN01000114_gene1676	1.66e-306	835.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,3XYMU@572511|Blautia	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
HGCANGJP_03043	457412.RSAG_01310	7.25e-201	555.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia,3WKHA@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
HGCANGJP_03044	457412.RSAG_01309	7.01e-217	599.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3WI18@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
HGCANGJP_03045	457412.RSAG_01764	1.26e-212	586.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,3WKHG@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
HGCANGJP_03046	1121115.AXVN01000086_gene4015	9.18e-222	615.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,3Y0ZK@572511|Blautia	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
HGCANGJP_03047	1121115.AXVN01000086_gene4014	5.64e-276	754.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XZNH@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
HGCANGJP_03048	1121115.AXVN01000086_gene4013	3.65e-173	484.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,3XZ48@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HGCANGJP_03049	1121115.AXVN01000086_gene4012	6.28e-118	338.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,3XZUS@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
HGCANGJP_03050	1121115.AXVN01000086_gene4011	0.0	869.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZ7S@572511|Blautia	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase 51 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
HGCANGJP_03051	1121115.AXVN01000086_gene4010	9.07e-52	164.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3Y0FT@572511|Blautia	186801|Clostridia	CQ	COG COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
HGCANGJP_03052	457412.RSAG_01771	2.7e-146	412.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3WJCD@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
HGCANGJP_03053	1121115.AXVN01000086_gene4008	1.22e-69	214.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HGCANGJP_03054	1121115.AXVN01000086_gene4007	1.77e-62	191.0	COG4577@1|root,COG4577@2|Bacteria,1V9YU@1239|Firmicutes,24MUN@186801|Clostridia,3Y0DW@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HGCANGJP_03055	1121115.AXVN01000086_gene4006	7.33e-51	161.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HGCANGJP_03056	1121115.AXVN01000086_gene4005	2.19e-67	204.0	2CTB7@1|root,32ST1@2|Bacteria,1UPS8@1239|Firmicutes,25HN2@186801|Clostridia	186801|Clostridia	S	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HGCANGJP_03057	1121115.AXVN01000086_gene4004	3.85e-301	820.0	COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3XYZP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
HGCANGJP_03058	457412.RSAG_01777	0.0	910.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3WNQC@541000|Ruminococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	eutE	-	1.2.1.10,1.2.1.87	ko:K00132,ko:K13922	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00228,R01172,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
HGCANGJP_03059	457412.RSAG_01778	5.57e-214	590.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3WHFE@541000|Ruminococcaceae	186801|Clostridia	G	L-fuculose phosphate aldolase	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
HGCANGJP_03060	457412.RSAG_01779	1.4e-195	541.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,3WIZP@541000|Ruminococcaceae	186801|Clostridia	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HGCANGJP_03061	457412.RSAG_01780	0.0	1699.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3WH79@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate formate lyase	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HGCANGJP_03062	1121115.AXVN01000086_gene3999	2.6e-88	259.0	2EYFK@1|root,33RPH@2|Bacteria,1VT8U@1239|Firmicutes,24XWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03063	457412.RSAG_00865	4.97e-97	282.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia,3WGSA@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulators	mgrA	-	-	-	-	-	-	-	-	-	-	-	MarR
HGCANGJP_03064	1280698.AUJS01000042_gene3266	3.18e-175	487.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
HGCANGJP_03065	457412.RSAG_00863	6.86e-227	624.0	COG1533@1|root,COG1533@2|Bacteria,1TRIS@1239|Firmicutes,25CEW@186801|Clostridia,3WGZD@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
HGCANGJP_03066	457412.RSAG_00862	1.35e-178	500.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
HGCANGJP_03067	457412.RSAG_00860	3.14e-132	374.0	COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia,3WIZ6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HGCANGJP_03068	457412.RSAG_00003	4.43e-55	173.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,3WKRS@541000|Ruminococcaceae	186801|Clostridia	S	Small, acid-soluble spore protein, alpha beta type	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
HGCANGJP_03069	1121115.AXVN01000002_gene1367	1.27e-90	265.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3Y038@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
HGCANGJP_03070	1121115.AXVN01000002_gene1368	4.62e-125	356.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3XZUU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
HGCANGJP_03071	1121115.AXVN01000002_gene1369	9.62e-111	318.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3XZXZ@572511|Blautia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
HGCANGJP_03072	1121115.AXVN01000002_gene1370	2.51e-94	281.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03073	1121115.AXVN01000002_gene1371	1.13e-219	606.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3Y01Q@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
HGCANGJP_03074	1121115.AXVN01000002_gene1372	0.0	954.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,3XZA8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
HGCANGJP_03075	1121115.AXVN01000002_gene1373	2.49e-188	523.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,3XZGG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
HGCANGJP_03076	1121115.AXVN01000002_gene1374	0.0	1294.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3XYGY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
HGCANGJP_03077	457412.RSAG_00012	1.83e-150	423.0	2E2IE@1|root,32XN3@2|Bacteria,1VD21@1239|Firmicutes,24KKS@186801|Clostridia,3WM0H@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03078	1121115.AXVN01000002_gene1376	1.6e-247	679.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3XYMC@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
HGCANGJP_03079	1121115.AXVN01000002_gene1377	6.57e-107	310.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
HGCANGJP_03080	1121115.AXVN01000002_gene1378	6.15e-127	360.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,3XZTT@572511|Blautia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
HGCANGJP_03082	1121115.AXVN01000155_gene552	2.54e-176	493.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,24JI9@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
HGCANGJP_03083	457412.RSAG_01589	3.44e-60	186.0	2C1NT@1|root,32JUU@2|Bacteria,1V7IC@1239|Firmicutes,24JFE@186801|Clostridia,3WPC1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03084	411463.EUBVEN_01785	1.91e-38	128.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,25XDD@186806|Eubacteriaceae	186801|Clostridia	K	adenine-specific DNA methyltransferase K06223	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
HGCANGJP_03085	457412.RSAG_01587	1.06e-65	200.0	292IX@1|root,2ZQ2Y@2|Bacteria,1TV0U@1239|Firmicutes,258A6@186801|Clostridia,3WMAJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03086	411459.RUMOBE_02222	1.18e-33	117.0	2EJ89@1|root,33CZF@2|Bacteria,1VNWZ@1239|Firmicutes,24RJS@186801|Clostridia,3Y1T6@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03087	1140001.I571_02512	1.3e-48	157.0	COG1359@1|root,COG1359@2|Bacteria,1V8JS@1239|Firmicutes,4HKAP@91061|Bacilli,4B3DQ@81852|Enterococcaceae	91061|Bacilli	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
HGCANGJP_03088	97139.C824_05915	1.1e-11	59.3	2C9RV@1|root,32TR5@2|Bacteria,1VDVS@1239|Firmicutes,25AYH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03089	457412.RSAG_01582	7.64e-42	153.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3WGIN@541000|Ruminococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
HGCANGJP_03090	1121115.AXVN01000048_gene1275	0.0	1913.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,SBP_bac_3
HGCANGJP_03091	1121115.AXVN01000048_gene1276	1.32e-61	188.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24KYU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03092	1121115.AXVN01000048_gene1277	2.41e-205	569.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
HGCANGJP_03093	1121115.AXVN01000048_gene1278	1.6e-189	528.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3Y13H@572511|Blautia	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
HGCANGJP_03094	1121115.AXVN01000048_gene1279	5.02e-52	164.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,3Y205@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
HGCANGJP_03095	457412.RSAG_01572	1.72e-69	209.0	COG0526@1|root,COG0526@2|Bacteria,1UG1U@1239|Firmicutes,24SF7@186801|Clostridia,3WKHR@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
HGCANGJP_03096	457412.RSAG_01571	3.42e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,3WKGM@541000|Ruminococcaceae	186801|Clostridia	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
HGCANGJP_03097	1121115.AXVN01000048_gene1282	5.7e-198	548.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3Y0YS@572511|Blautia	186801|Clostridia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
HGCANGJP_03098	457412.RSAG_01569	9.72e-103	296.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
HGCANGJP_03099	457412.RSAG_01568	0.0	1111.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WH9N@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA_7TM,Response_reg,SBP_bac_3
HGCANGJP_03100	457412.RSAG_01567	0.0	1030.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
HGCANGJP_03101	1121115.AXVN01000136_gene975	1e-289	791.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3XZRE@572511|Blautia	186801|Clostridia	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
HGCANGJP_03102	1121115.AXVN01000136_gene976	7.87e-126	357.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3Y0NR@572511|Blautia	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
HGCANGJP_03103	1121115.AXVN01000136_gene977	1.2e-95	278.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,3Y0F5@572511|Blautia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03104	457412.RSAG_01792	1.53e-208	575.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3WINQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03105	1121115.AXVN01000136_gene979	2.11e-139	395.0	COG0484@1|root,COG0484@2|Bacteria,1UWW2@1239|Firmicutes,25CGC@186801|Clostridia,3XZTD@572511|Blautia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
HGCANGJP_03106	1121115.AXVN01000136_gene980	2.43e-240	660.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,3XYQU@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
HGCANGJP_03107	1121115.AXVN01000136_gene981	8.41e-256	712.0	COG5263@1|root,COG5263@2|Bacteria,1UK2Z@1239|Firmicutes,24XW0@186801|Clostridia,3XZWP@572511|Blautia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
HGCANGJP_03108	1121115.AXVN01000126_gene3812	5.25e-208	591.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3XZ4Y@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
HGCANGJP_03109	1121115.AXVN01000126_gene3813	1.73e-81	241.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,3Y27X@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
HGCANGJP_03110	1121115.AXVN01000126_gene3814	5.64e-97	282.0	COG4810@1|root,COG4810@2|Bacteria,1V5A1@1239|Firmicutes,24IPC@186801|Clostridia,3Y03M@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
HGCANGJP_03111	457412.RSAG_01785	3.45e-121	345.0	COG4917@1|root,COG4917@2|Bacteria,1V54Y@1239|Firmicutes,25DMI@186801|Clostridia	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
HGCANGJP_03112	1121115.AXVN01000126_gene3816	6.65e-75	223.0	COG2158@1|root,COG2158@2|Bacteria,1VFNA@1239|Firmicutes,24MYB@186801|Clostridia,3Y0C2@572511|Blautia	186801|Clostridia	S	Cysteine-rich small domain	-	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
HGCANGJP_03113	457412.RSAG_01783	0.0	1475.0	COG4733@1|root,COG4870@1|root,COG4733@2|Bacteria,COG4870@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia,3WRJP@541000|Ruminococcaceae	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
HGCANGJP_03114	1121115.AXVN01000126_gene3818	1.46e-174	493.0	COG3266@1|root,COG3266@2|Bacteria,1VS06@1239|Firmicutes,24YEU@186801|Clostridia,3Y1K6@572511|Blautia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03115	1121115.AXVN01000090_gene2558	1.37e-64	196.0	2E7YJ@1|root,30FFS@2|Bacteria,1UDZU@1239|Firmicutes,25IU2@186801|Clostridia,3Y1VR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03116	457412.RSAG_02725	5.51e-200	553.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,3WGHY@541000|Ruminococcaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
HGCANGJP_03117	1121115.AXVN01000090_gene2560	2.83e-62	190.0	COG1598@1|root,COG1598@2|Bacteria,1VH8E@1239|Firmicutes,2586D@186801|Clostridia,3Y0CI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
HGCANGJP_03119	1121115.AXVN01000090_gene2562	2.95e-217	602.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3Y07K@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HGCANGJP_03120	1121115.AXVN01000090_gene2563	0.0	964.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,24XM1@186801|Clostridia	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_03121	1121115.AXVN01000090_gene2564	7.99e-253	693.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y0R4@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K17213	ko02010,map02010	M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
HGCANGJP_03122	1121115.AXVN01000090_gene2565	4.86e-261	714.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3XYNV@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
HGCANGJP_03123	1121115.AXVN01000090_gene2566	4.24e-220	607.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZKV@572511|Blautia	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HGCANGJP_03124	1121115.AXVN01000090_gene2567	1.2e-202	560.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZKM@572511|Blautia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HGCANGJP_03125	1121115.AXVN01000090_gene2568	0.0	1013.0	COG0554@1|root,COG0554@2|Bacteria,1TRX3@1239|Firmicutes,24A76@186801|Clostridia,3XZRZ@572511|Blautia	186801|Clostridia	C	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
HGCANGJP_03126	1121115.AXVN01000090_gene2569	2.68e-164	461.0	COG1349@1|root,COG1349@2|Bacteria,1VQV5@1239|Firmicutes,24YG9@186801|Clostridia	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
HGCANGJP_03127	1121115.AXVN01000090_gene2570	0.0	873.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3XZM9@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
HGCANGJP_03128	1121115.AXVN01000090_gene2571	1.98e-136	386.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
HGCANGJP_03129	1121115.AXVN01000090_gene2572	7.52e-303	825.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
HGCANGJP_03130	1121115.AXVN01000057_gene2514	2.97e-220	614.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
HGCANGJP_03131	1121115.AXVN01000057_gene2515	0.0	1138.0	2DUPK@1|root,33RK6@2|Bacteria,1VRQV@1239|Firmicutes,24YX7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03132	457412.RSAG_02820	9e-166	464.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3WG98@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_03133	457412.RSAG_02821	0.0	1576.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3WGNX@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
HGCANGJP_03134	556261.HMPREF0240_04213	2.23e-136	393.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,36E2H@31979|Clostridiaceae	186801|Clostridia	K	transcriptional antiterminator	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
HGCANGJP_03135	658655.HMPREF0988_00931	1.07e-72	222.0	COG2190@1|root,COG2190@2|Bacteria,1W092@1239|Firmicutes,25EGH@186801|Clostridia,27UE8@186928|unclassified Lachnospiraceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1	ptbA	-	-	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	M00271	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6	-	-	PTS_EIIA_1
HGCANGJP_03136	658655.HMPREF0988_00930	1.05e-299	823.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,27JKG@186928|unclassified Lachnospiraceae	186801|Clostridia	G	phosphotransferase system, EIIB	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
HGCANGJP_03137	397288.C806_01835	3.15e-06	52.4	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,1VR4E@1239|Firmicutes,24ZX9@186801|Clostridia,27R20@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
HGCANGJP_03138	1304866.K413DRAFT_2113	7.77e-53	177.0	COG1802@1|root,COG1802@2|Bacteria,1UX0V@1239|Firmicutes,25MUT@186801|Clostridia,36TTV@31979|Clostridiaceae	186801|Clostridia	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
HGCANGJP_03139	742735.HMPREF9467_05084	2.34e-150	434.0	COG0399@1|root,COG0399@2|Bacteria,1V9T5@1239|Firmicutes,24F34@186801|Clostridia,21ZPY@1506553|Lachnoclostridium	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03140	411902.CLOBOL_01070	1.64e-126	367.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,21XHD@1506553|Lachnoclostridium	186801|Clostridia	P	COG COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
HGCANGJP_03141	1121115.AXVN01000099_gene778	1.6e-55	174.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
HGCANGJP_03142	1121115.AXVN01000099_gene779	3.38e-46	149.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3Y0D7@572511|Blautia	186801|Clostridia	J	COG COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
HGCANGJP_03143	457412.RSAG_03274	4.7e-57	177.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
HGCANGJP_03144	457412.RSAG_03275	4.14e-102	296.0	2EFTM@1|root,3095D@2|Bacteria,1U4G7@1239|Firmicutes,25JHX@186801|Clostridia,3WR8N@541000|Ruminococcaceae	186801|Clostridia	S	Spore cortex protein YabQ (Spore_YabQ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
HGCANGJP_03145	457412.RSAG_03276	2.36e-47	153.0	COG2919@1|root,COG2919@2|Bacteria,1VX29@1239|Firmicutes,252JU@186801|Clostridia,3WMKM@541000|Ruminococcaceae	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
HGCANGJP_03146	457412.RSAG_03277	0.0	981.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
HGCANGJP_03147	457412.RSAG_03278	0.0	966.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
HGCANGJP_03148	457412.RSAG_04578	3.04e-122	348.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
HGCANGJP_03149	1121115.AXVN01000099_gene785	0.0	1140.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYI4@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
HGCANGJP_03150	1121115.AXVN01000099_gene786	0.0	1474.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3XYPB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
HGCANGJP_03152	1121115.AXVN01000099_gene787	1.41e-207	573.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
HGCANGJP_03153	457412.RSAG_03282	0.0	921.0	COG1376@1|root,COG1376@2|Bacteria,1W706@1239|Firmicutes,258MI@186801|Clostridia,3WN4E@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HGCANGJP_03154	457412.RSAG_03283	4.67e-127	361.0	COG0778@1|root,COG0778@2|Bacteria,1V80D@1239|Firmicutes,24I9R@186801|Clostridia,3WRRJ@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
HGCANGJP_03156	1121115.AXVN01000017_gene239	1.87e-121	351.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,3Y0V5@572511|Blautia	186801|Clostridia	NOU	Type IV leader peptidase family	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
HGCANGJP_03157	1121115.AXVN01000017_gene238	0.0	909.0	COG4972@1|root,COG4972@2|Bacteria,1V3TN@1239|Firmicutes,24ASH@186801|Clostridia	186801|Clostridia	NU	Type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2,PilN
HGCANGJP_03158	1121115.AXVN01000017_gene237	1.26e-174	494.0	29Y5S@1|root,31E01@2|Bacteria,1V6MG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03159	1121115.AXVN01000017_gene236	3.39e-163	482.0	COG4967@1|root,COG4967@2|Bacteria,1VKH2@1239|Firmicutes,24UHG@186801|Clostridia	186801|Clostridia	NU	type IV pilus modification protein PilV	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HGCANGJP_03160	1121115.AXVN01000017_gene235	6.16e-253	731.0	2EAGJ@1|root,334JU@2|Bacteria,1VH9K@1239|Firmicutes,24IKS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03161	1121115.AXVN01000017_gene234	1.41e-73	227.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	ppdA	-	-	ko:K02679,ko:K08084,ko:K08085	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
HGCANGJP_03162	1121115.AXVN01000017_gene233	2.78e-186	588.0	COG2165@1|root,COG2165@2|Bacteria,1W06U@1239|Firmicutes	1239|Firmicutes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HGCANGJP_03163	478749.BRYFOR_09877	1.09e-168	482.0	COG1106@1|root,COG1106@2|Bacteria,1UZQP@1239|Firmicutes,24B12@186801|Clostridia	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
HGCANGJP_03164	1280680.AUJU01000005_gene1551	1.45e-22	88.2	2BSPA@1|root,32MRZ@2|Bacteria,1TUTY@1239|Firmicutes,2597K@186801|Clostridia,4C0IA@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03165	1121115.AXVN01000017_gene232	0.0	1437.0	COG5492@1|root,COG5492@2|Bacteria,1TT7E@1239|Firmicutes,24J1K@186801|Clostridia	186801|Clostridia	N	Domain of unknown function (DUF5057)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5057
HGCANGJP_03166	1121115.AXVN01000064_gene4026	2.81e-56	179.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3Y0B2@572511|Blautia	186801|Clostridia	Q	Phosphate propanoyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
HGCANGJP_03167	457412.RSAG_00227	0.0	1266.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
HGCANGJP_03168	1121115.AXVN01000064_gene4020	0.0	1400.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3XYIK@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	ptsG	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HGCANGJP_03169	1121115.AXVN01000064_gene4021	2.15e-197	547.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,249XA@186801|Clostridia,3Y2CD@572511|Blautia	186801|Clostridia	K	CAT RNA binding domain	bglG	-	-	ko:K03480	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
HGCANGJP_03170	411459.RUMOBE_02313	7.03e-87	270.0	COG4968@1|root,COG4968@2|Bacteria,1VD7G@1239|Firmicutes,25FI2@186801|Clostridia,3Y0V4@572511|Blautia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
HGCANGJP_03171	1121115.AXVN01000064_gene4022	0.0	1744.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	1239|Firmicutes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
HGCANGJP_03172	1121115.AXVN01000064_gene4023	0.0	877.0	COG0840@1|root,COG2199@1|root,COG0840@2|Bacteria,COG2199@2|Bacteria,1TQG9@1239|Firmicutes,249KA@186801|Clostridia,3Y0T6@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HGCANGJP_03173	1121115.AXVN01000140_gene2945	4.36e-103	298.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia	186801|Clostridia	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HGCANGJP_03174	1121115.AXVN01000140_gene2946	2.26e-156	440.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia	186801|Clostridia	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
HGCANGJP_03175	1121115.AXVN01000064_gene4025	1.76e-197	548.0	28JN4@1|root,31UVI@2|Bacteria,1V2P0@1239|Firmicutes,25EHE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03176	1121115.AXVN01000064_gene4026	4.71e-155	434.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3Y0B2@572511|Blautia	186801|Clostridia	Q	Phosphate propanoyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
HGCANGJP_03177	1121115.AXVN01000025_gene943	7.08e-295	803.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia,3XZN1@572511|Blautia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
HGCANGJP_03178	1121115.AXVN01000025_gene944	7.39e-159	448.0	2E6QY@1|root,331B3@2|Bacteria,1UI1C@1239|Firmicutes,24Z9X@186801|Clostridia,3Y0GV@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
HGCANGJP_03179	457412.RSAG_00215	4.18e-118	338.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
HGCANGJP_03180	1121115.AXVN01000025_gene946	0.0	1071.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,3XZ1S@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
HGCANGJP_03181	1121115.AXVN01000025_gene947	2.17e-93	272.0	COG1959@1|root,COG1959@2|Bacteria,1VA5B@1239|Firmicutes,24JMN@186801|Clostridia,3Y09T@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
HGCANGJP_03182	1121115.AXVN01000025_gene948	0.0	2341.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
HGCANGJP_03183	457412.RSAG_00211	0.0	1768.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3WHMX@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
HGCANGJP_03184	1121115.AXVN01000025_gene950	2.09e-220	608.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3XYSZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
HGCANGJP_03185	1121115.AXVN01000025_gene951	1.24e-89	263.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,257NM@186801|Clostridia,3Y0BG@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
HGCANGJP_03186	1121115.AXVN01000025_gene952	1.26e-244	672.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3XYHW@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
HGCANGJP_03187	1121115.AXVN01000025_gene953	4.82e-121	346.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3Y004@572511|Blautia	186801|Clostridia	H	COG COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
HGCANGJP_03188	1121115.AXVN01000025_gene954	4.31e-183	509.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3Y00I@572511|Blautia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
HGCANGJP_03189	1121115.AXVN01000025_gene955	4.69e-86	253.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
HGCANGJP_03190	1121115.AXVN01000025_gene956	2.18e-149	419.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3XZUY@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
HGCANGJP_03191	1121115.AXVN01000025_gene957	0.0	912.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZEP@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
HGCANGJP_03192	1121115.AXVN01000025_gene958	0.0	1955.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,3XYRC@572511|Blautia	186801|Clostridia	C	COG COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
HGCANGJP_03193	1121115.AXVN01000025_gene959	0.0	1754.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYY3@572511|Blautia	186801|Clostridia	C	COG COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	mop	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
HGCANGJP_03194	457412.RSAG_00200	3.71e-94	276.0	COG1148@1|root,COG1148@2|Bacteria,1V4P9@1239|Firmicutes,24IV2@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
HGCANGJP_03195	457412.RSAG_00199	0.0	1509.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhA	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
HGCANGJP_03196	1121115.AXVN01000025_gene962	2.61e-202	561.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,3XZ4A@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	xdhB	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
HGCANGJP_03197	457412.RSAG_00197	2.18e-117	335.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,3WPIS@541000|Ruminococcaceae	186801|Clostridia	C	[2Fe-2S] binding domain	cutS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
HGCANGJP_03198	457412.RSAG_00196	2.75e-212	586.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
HGCANGJP_03199	457412.RSAG_00195	1.05e-164	461.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03200	457412.RSAG_04726	5.86e-157	441.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,3WKNV@541000|Ruminococcaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
HGCANGJP_03201	1121115.AXVN01000134_gene411	6.82e-224	617.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3XZFB@572511|Blautia	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
HGCANGJP_03202	1121115.AXVN01000134_gene412	8.61e-294	801.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,3XYQV@572511|Blautia	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	ygeW	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
HGCANGJP_03203	1121115.AXVN01000134_gene413	0.0	900.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,3XYM0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
HGCANGJP_03204	457412.RSAG_00191	9.5e-304	827.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,3WHJ2@541000|Ruminococcaceae	186801|Clostridia	E	Diaminopropionate ammonia-lyase	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
HGCANGJP_03205	457412.RSAG_00190	2.66e-312	849.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3WK6T@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
HGCANGJP_03206	1121115.AXVN01000032_gene374	3.18e-41	139.0	28SNZ@1|root,2ZEZ7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03208	1121115.AXVN01000032_gene376	0.0	1110.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3XYGQ@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
HGCANGJP_03209	1121115.AXVN01000032_gene377	0.0	1518.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
HGCANGJP_03210	1121115.AXVN01000032_gene378	1.1e-187	520.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3XYYY@572511|Blautia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
HGCANGJP_03211	457412.RSAG_00185	0.0	1678.0	COG0500@1|root,COG3608@1|root,COG2226@2|Bacteria,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3WJ0E@541000|Ruminococcaceae	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
HGCANGJP_03212	457412.RSAG_00183	1.75e-192	535.0	COG3773@1|root,COG3773@2|Bacteria,1VAUD@1239|Firmicutes,25B1B@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,LysM
HGCANGJP_03213	1121115.AXVN01000032_gene381	0.0	970.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
HGCANGJP_03214	457412.RSAG_00180	1.25e-266	728.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3WH61@541000|Ruminococcaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
HGCANGJP_03215	457412.RSAG_00179	3.4e-200	556.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,3WJ77@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
HGCANGJP_03216	1121115.AXVN01000005_gene2236	7.23e-85	250.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,3Y0KX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
HGCANGJP_03217	1121115.AXVN01000005_gene2237	3.44e-190	526.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3XYR4@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 9.98	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
HGCANGJP_03218	1121115.AXVN01000005_gene2238	0.0	1301.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZJM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase
HGCANGJP_03219	1121115.AXVN01000005_gene2239	1.68e-141	398.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3XZW0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	KatE	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03220	457412.RSAG_03029	0.0	937.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
HGCANGJP_03221	457412.RSAG_03028	3.55e-282	769.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3WHCZ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
HGCANGJP_03222	457412.RSAG_03027	1.11e-126	361.0	2C0IG@1|root,324G4@2|Bacteria,1UQRN@1239|Firmicutes,258HV@186801|Clostridia,3WMTD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03223	457412.RSAG_03026	0.0	1922.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
HGCANGJP_03224	457412.RSAG_03025	2.37e-218	602.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
HGCANGJP_03225	1121115.AXVN01000005_gene2245	4.31e-179	498.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3XYR9@572511|Blautia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
HGCANGJP_03226	1121115.AXVN01000005_gene2246	0.0	967.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3XZ0N@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
HGCANGJP_03227	1121115.AXVN01000022_gene1745	0.0	1185.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3XYYN@572511|Blautia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
HGCANGJP_03228	1121115.AXVN01000022_gene1744	1.43e-51	165.0	2CAIE@1|root,33XMU@2|Bacteria,1VVJ5@1239|Firmicutes,2511G@186801|Clostridia,3Y25M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03229	457412.RSAG_02145	3.42e-280	765.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
HGCANGJP_03230	1121115.AXVN01000022_gene1742	0.0	1869.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
HGCANGJP_03231	1121115.AXVN01000022_gene1741	1.13e-225	623.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3XZC7@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
HGCANGJP_03232	457412.RSAG_02140	0.0	1458.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3WGP3@541000|Ruminococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
HGCANGJP_03233	1121115.AXVN01000022_gene1739	6.14e-176	489.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3Y06Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
HGCANGJP_03234	1121115.AXVN01000022_gene1738	7.07e-92	269.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia,3Y0CW@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03235	457412.RSAG_02137	2.55e-247	681.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,3WIZQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03236	457412.RSAG_01085	2.7e-199	553.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
HGCANGJP_03237	457412.RSAG_01084	7.36e-55	171.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
HGCANGJP_03238	457412.RSAG_01083	2.41e-141	399.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
HGCANGJP_03239	1121115.AXVN01000001_gene1061	4.72e-49	159.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,257WP@186801|Clostridia,3Y0N6@572511|Blautia	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
HGCANGJP_03240	1121115.AXVN01000001_gene1060	0.0	880.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3XYI9@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
HGCANGJP_03241	1121115.AXVN01000001_gene1059	5.22e-120	343.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3XZV4@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
HGCANGJP_03242	1121115.AXVN01000001_gene1058	1e-101	296.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3Y099@572511|Blautia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
HGCANGJP_03243	1121115.AXVN01000001_gene1057	1.49e-54	171.0	2EMJQ@1|root,32KAG@2|Bacteria,1URUU@1239|Firmicutes,259SC@186801|Clostridia,3Y0NU@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03244	457412.RSAG_01077	4.78e-79	235.0	2BB22@1|root,325BH@2|Bacteria,1URE9@1239|Firmicutes,259TU@186801|Clostridia,3WQP9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03245	457412.RSAG_01076	6.33e-31	108.0	2FGS5@1|root,348MK@2|Bacteria,1W0U5@1239|Firmicutes,2540A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03246	1121115.AXVN01000001_gene1054	1.1e-29	109.0	2F3CT@1|root,33W6S@2|Bacteria,1VVCN@1239|Firmicutes,250TA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03247	457412.RSAG_01073	4.11e-204	579.0	COG5263@1|root,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3WQ86@541000|Ruminococcaceae	186801|Clostridia	M	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_5,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
HGCANGJP_03248	1121115.AXVN01000001_gene1052	9.11e-302	822.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
HGCANGJP_03249	457412.RSAG_01071	0.0	1625.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
HGCANGJP_03250	1121115.AXVN01000045_gene2073	1.35e-199	552.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3XZZB@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
HGCANGJP_03251	457412.RSAG_00842	0.0	870.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
HGCANGJP_03252	1121115.AXVN01000045_gene2071	0.0	930.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
HGCANGJP_03253	1121115.AXVN01000045_gene2070	2.04e-157	442.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3XZJ5@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
HGCANGJP_03254	1121115.AXVN01000045_gene2069	8.52e-135	384.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3XYV9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
HGCANGJP_03255	1121115.AXVN01000045_gene2068	1.58e-189	529.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3XYR5@572511|Blautia	186801|Clostridia	ET	cystine-binding periplasmic protein precursor	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
HGCANGJP_03256	457412.RSAG_00846	3e-161	454.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24D1P@186801|Clostridia,3WJTT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
HGCANGJP_03257	1121115.AXVN01000045_gene2066	3.11e-312	849.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,3XZBP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03258	457412.RSAG_00848	0.0	2372.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,3WH59@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03259	457412.RSAG_00025	3.81e-275	753.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHJY@541000|Ruminococcaceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
HGCANGJP_03260	1121115.AXVN01000002_gene1388	7.03e-225	622.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3Y151@572511|Blautia	186801|Clostridia	P	FecCD transport family	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
HGCANGJP_03261	457412.RSAG_00023	5.12e-286	781.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
HGCANGJP_03262	457412.RSAG_00022	1.19e-193	543.0	COG0614@1|root,COG5386@1|root,COG0614@2|Bacteria,COG5386@2|Bacteria,1UYC0@1239|Firmicutes,24D7G@186801|Clostridia,3WSRF@541000|Ruminococcaceae	186801|Clostridia	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03263	457412.RSAG_00021	2.62e-279	770.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
HGCANGJP_03264	1121115.AXVN01000002_gene1383	1.06e-80	239.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3XZDT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
HGCANGJP_03265	1121115.AXVN01000002_gene1382	3.77e-139	393.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3XYJ4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
HGCANGJP_03266	1121115.AXVN01000002_gene1381	2.25e-301	823.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3XZ14@572511|Blautia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
HGCANGJP_03267	1121115.AXVN01000002_gene1380	1.76e-147	416.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3XZ1U@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
HGCANGJP_03268	1121115.AXVN01000002_gene1379	7.22e-262	718.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,3XYWI@572511|Blautia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
HGCANGJP_03269	1121115.AXVN01000207_gene3755	3.31e-112	327.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia,3Y1U0@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
HGCANGJP_03270	1121115.AXVN01000116_gene2324	0.0	1465.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3XZJV@572511|Blautia	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
HGCANGJP_03272	643648.Slip_1624	8.21e-10	65.1	COG1388@1|root,COG3409@1|root,COG1388@2|Bacteria,COG3409@2|Bacteria,1V5FY@1239|Firmicutes,24H9R@186801|Clostridia,42K2Q@68298|Syntrophomonadaceae	186801|Clostridia	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HGCANGJP_03273	1121115.AXVN01000116_gene2326	0.0	1332.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XYP0@572511|Blautia	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
HGCANGJP_03274	1121115.AXVN01000116_gene2327	0.0	874.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
HGCANGJP_03275	1121115.AXVN01000071_gene3935	8.74e-175	488.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3XZMC@572511|Blautia	186801|Clostridia	S	Uncharacterised protein family UPF0066	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
HGCANGJP_03276	457412.RSAG_01747	0.0	865.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
HGCANGJP_03277	457412.RSAG_01410	5.51e-205	567.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,3WGRW@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HGCANGJP_03278	457412.RSAG_04514	5.14e-42	137.0	2CA4K@1|root,347XV@2|Bacteria,1VZ7Z@1239|Firmicutes,253MY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03279	1121115.AXVN01000010_gene2800	2.83e-210	582.0	2DS3C@1|root,33EBY@2|Bacteria,1U8VV@1239|Firmicutes,24EGD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
HGCANGJP_03280	457412.RSAG_01408	1.42e-290	796.0	COG4632@1|root,COG5263@1|root,COG4632@2|Bacteria,COG5263@2|Bacteria,1TR6Z@1239|Firmicutes,25B3H@186801|Clostridia,3WJIW@541000|Ruminococcaceae	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
HGCANGJP_03281	1121115.AXVN01000010_gene2802	4.36e-22	85.9	2CA4N@1|root,2ZQ5H@2|Bacteria,1W5T5@1239|Firmicutes,256DT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03282	457412.RSAG_01406	9.71e-317	862.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae	186801|Clostridia	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
HGCANGJP_03283	457412.RSAG_01405	0.0	912.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WIPN@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
HGCANGJP_03284	457412.RSAG_01404	1.33e-255	700.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
HGCANGJP_03285	457412.RSAG_01403	0.0	901.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
HGCANGJP_03286	1121115.AXVN01000010_gene2808	1.85e-136	386.0	2EXAI@1|root,33QM6@2|Bacteria,1VU0R@1239|Firmicutes,24YTY@186801|Clostridia,3Y0G1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03287	457412.RSAG_01401	2.09e-63	193.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,3WKW0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03288	515620.EUBELI_20171	4.19e-173	488.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,25W4Z@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran,DUF4162
HGCANGJP_03289	457412.RSAG_00897	6.14e-204	565.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,3WM6R@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
HGCANGJP_03290	457412.RSAG_00896	0.0	1757.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TVCK@1239|Firmicutes,25KKE@186801|Clostridia,3WNVM@541000|Ruminococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
HGCANGJP_03291	457412.RSAG_00894	2.46e-62	193.0	COG2198@1|root,COG3437@1|root,COG2198@2|Bacteria,COG3437@2|Bacteria,1VG8R@1239|Firmicutes,24QS0@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
HGCANGJP_03292	457412.RSAG_00893	4.64e-22	87.4	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,25AYI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03293	457412.RSAG_00892	9.16e-105	302.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HGCANGJP_03294	457412.RSAG_00891	2.81e-181	504.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
HGCANGJP_03295	742733.HMPREF9469_01293	8.13e-184	516.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia,21YC3@1506553|Lachnoclostridium	186801|Clostridia	L	COG NOG34358 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HGCANGJP_03296	742733.HMPREF9469_01292	1.87e-91	269.0	2DBBE@1|root,2Z87W@2|Bacteria,1UYXC@1239|Firmicutes,25CI0@186801|Clostridia,22496@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
HGCANGJP_03297	1226322.HMPREF1545_01615	1.48e-231	642.0	COG1961@1|root,COG3505@1|root,COG1961@2|Bacteria,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,2N6FC@216572|Oscillospiraceae	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
HGCANGJP_03298	457412.RSAG_03146	4.29e-148	490.0	COG3209@1|root,COG3209@2|Bacteria,1TRJ1@1239|Firmicutes,24AU6@186801|Clostridia,3WHF3@541000|Ruminococcaceae	186801|Clostridia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5,Transglut_core
HGCANGJP_03299	622312.ROSEINA2194_03624	1.01e-310	849.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
HGCANGJP_03300	457412.RSAG_03137	2.49e-230	634.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HGCANGJP_03301	457412.RSAG_03138	3.99e-198	550.0	COG1047@1|root,COG1433@1|root,COG1047@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,24BUF@186801|Clostridia	186801|Clostridia	O	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Nitro_FeMo-Co
HGCANGJP_03302	1121115.AXVN01000137_gene1822	0.0	1486.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UVFQ@1239|Firmicutes,25KHE@186801|Clostridia,3Y1SM@572511|Blautia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03303	1121115.AXVN01000051_gene806	2.2e-224	619.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,3Y29U@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
HGCANGJP_03304	1235798.C817_02839	7.27e-129	372.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,27VID@189330|Dorea	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
HGCANGJP_03305	500632.CLONEX_01807	1.99e-214	599.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
HGCANGJP_03306	1121115.AXVN01000051_gene807	0.0	1706.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4384,TonB_dep_Rec
HGCANGJP_03308	1121115.AXVN01000051_gene809	1.08e-216	597.0	COG0791@1|root,COG0791@2|Bacteria,1VICE@1239|Firmicutes,25BYF@186801|Clostridia	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,NLPC_P60,SH3_3
HGCANGJP_03309	1121115.AXVN01000051_gene810	1.96e-71	215.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24UEE@186801|Clostridia	186801|Clostridia	K	helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_03310	1121115.AXVN01000051_gene811	3.26e-130	369.0	2EHNM@1|root,33BEE@2|Bacteria,1VNIH@1239|Firmicutes,24PUV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03311	1121115.AXVN01000051_gene812	1.31e-103	303.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia,3Y1SH@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_03312	1121115.AXVN01000051_gene812	8.22e-47	155.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia,3Y1SH@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
HGCANGJP_03313	411462.DORLON_00164	5.4e-118	338.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,27W90@189330|Dorea	186801|Clostridia	C	COG COG0716 Flavodoxins	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
HGCANGJP_03314	457412.RSAG_00595	1.03e-193	536.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,3WGGH@541000|Ruminococcaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
HGCANGJP_03315	1256908.HMPREF0373_01472	2.58e-250	690.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,25VJA@186806|Eubacteriaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
HGCANGJP_03316	1121115.AXVN01000003_gene1516	3.33e-47	151.0	2E255@1|root,32XC6@2|Bacteria,1VASU@1239|Firmicutes,25PWU@186801|Clostridia,3Y1UH@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
HGCANGJP_03317	411459.RUMOBE_00590	0.0	1384.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,3XZ30@572511|Blautia	186801|Clostridia	M	penicillin-binding protein 2'	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
HGCANGJP_03318	411459.RUMOBE_00589	4.71e-285	778.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,3XZZK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03319	411459.RUMOBE_00588	3.2e-305	831.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,3XZIT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03320	411459.RUMOBE_00587	0.0	1169.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,3XYWY@572511|Blautia	186801|Clostridia	KTV	Psort location CytoplasmicMembrane, score	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
HGCANGJP_03321	411459.RUMOBE_00586	7.88e-79	234.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,3Y08G@572511|Blautia	186801|Clostridia	K	beta-lactamase (penicillinase) repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
HGCANGJP_03322	411459.RUMOBE_00585	4.71e-98	284.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,3Y0QH@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HGCANGJP_03323	457412.RSAG_01399	3.03e-61	205.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,3WH72@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_03324	1219626.HMPREF1639_08040	2.9e-79	235.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,25RHS@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
HGCANGJP_03325	1000569.HMPREF1040_0294	0.0	1454.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H27R@909932|Negativicutes	909932|Negativicutes	P	cadmium-exporting ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
HGCANGJP_03326	796942.HMPREF9623_00428	1.51e-111	321.0	28ITS@1|root,2Z8SN@2|Bacteria,1TRFF@1239|Firmicutes,24CE6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03327	1256908.HMPREF0373_00327	7.64e-113	325.0	28MNW@1|root,2ZAYB@2|Bacteria,1UZY0@1239|Firmicutes,24E0J@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03328	457412.RSAG_00558	0.0	1021.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WSK9@541000|Ruminococcaceae	186801|Clostridia	C	COG COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
HGCANGJP_03329	457412.RSAG_00557	2.32e-170	475.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia,3WH5I@541000|Ruminococcaceae	186801|Clostridia	C	succinate dehydrogenase iron-sulfur	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
HGCANGJP_03330	1121115.AXVN01000053_gene1846	9.55e-161	452.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,24958@186801|Clostridia	186801|Clostridia	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
HGCANGJP_03331	1121115.AXVN01000053_gene1847	1.07e-94	276.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,3Y0W0@572511|Blautia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HGCANGJP_03332	411470.RUMGNA_03479	3.12e-97	285.0	COG1846@1|root,COG1846@2|Bacteria,1UK34@1239|Firmicutes,24Y1H@186801|Clostridia,3XZJB@572511|Blautia	186801|Clostridia	K	COG NOG16925 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
HGCANGJP_03333	1235802.C823_05456	2.51e-159	453.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1UQRR@1239|Firmicutes,24BSD@186801|Clostridia,25Y7A@186806|Eubacteriaceae	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
HGCANGJP_03334	1235802.C823_05456	6.98e-94	283.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1UQRR@1239|Firmicutes,24BSD@186801|Clostridia,25Y7A@186806|Eubacteriaceae	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
HGCANGJP_03335	1121115.AXVN01000044_gene2044	3.96e-68	206.0	COG1476@1|root,COG1476@2|Bacteria,1V6EB@1239|Firmicutes,24KVB@186801|Clostridia,3Y1QU@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HGCANGJP_03336	411459.RUMOBE_02197	4.65e-158	443.0	COG0745@1|root,COG0745@2|Bacteria,1TT2Z@1239|Firmicutes,248PN@186801|Clostridia,3Y028@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_03337	1121115.AXVN01000044_gene2043	2.97e-213	589.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3XZQA@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_03338	411459.RUMOBE_02195	1.95e-171	479.0	COG1277@1|root,COG1277@2|Bacteria,1VIB7@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
HGCANGJP_03339	411459.RUMOBE_02193	7.11e-201	558.0	COG0642@1|root,COG2205@2|Bacteria,1UZ8S@1239|Firmicutes,25E8V@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_03340	411459.RUMOBE_00598	5.3e-111	319.0	COG1595@1|root,COG1595@2|Bacteria,1VBJI@1239|Firmicutes,24NKR@186801|Clostridia,3Y1WC@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_03341	411459.RUMOBE_00597	4.49e-183	509.0	29NVG@1|root,309TJ@2|Bacteria,1V4I1@1239|Firmicutes,24AMS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03342	411459.RUMOBE_00596	1.52e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_03343	411459.RUMOBE_00595	3.21e-285	780.0	COG1668@1|root,COG1668@2|Bacteria,1UY5S@1239|Firmicutes,24DP3@186801|Clostridia	186801|Clostridia	CP	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HGCANGJP_03344	411459.RUMOBE_00594	1.75e-91	267.0	COG0745@1|root,COG0745@2|Bacteria,1UVF6@1239|Firmicutes,25M0N@186801|Clostridia,3Y1TD@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HGCANGJP_03345	1121115.AXVN01000095_gene456	2.08e-10	60.8	2C2YH@1|root,31RJ6@2|Bacteria,1V7NS@1239|Firmicutes,24M7H@186801|Clostridia,3Y0EZ@572511|Blautia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HGCANGJP_03346	515622.bpr_I2877	1.72e-168	477.0	COG4823@1|root,COG4823@2|Bacteria	2|Bacteria	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
HGCANGJP_03347	476272.RUMHYD_03921	1.5e-74	229.0	COG1595@1|root,COG1595@2|Bacteria,1VH4V@1239|Firmicutes,25BGS@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_03348	476272.RUMHYD_01400	2.36e-64	208.0	2FFUY@1|root,347S0@2|Bacteria,1VYP7@1239|Firmicutes,253QZ@186801|Clostridia,3Y23M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03349	476272.RUMHYD_01401	3.64e-150	429.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_03350	476272.RUMHYD_01402	7.82e-134	394.0	COG1277@1|root,COG1277@2|Bacteria,1VWKS@1239|Firmicutes,25M9V@186801|Clostridia,3Y21D@572511|Blautia	186801|Clostridia	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03351	411469.EUBHAL_02124	3.41e-46	149.0	COG0745@1|root,COG0745@2|Bacteria,1VCPH@1239|Firmicutes,24MRK@186801|Clostridia,25YZC@186806|Eubacteriaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HGCANGJP_03352	742741.HMPREF9475_02736	9.99e-40	131.0	2E9U2@1|root,33400@2|Bacteria,1VGEQ@1239|Firmicutes,258EK@186801|Clostridia,223BE@1506553|Lachnoclostridium	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
HGCANGJP_03353	1235798.C817_03947	3.04e-143	410.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia,27WSX@189330|Dorea	186801|Clostridia	K	helix_turn_helix, mercury resistance	mta	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase,MerR_1,TipAS
HGCANGJP_03354	1235835.C814_02681	5.84e-306	836.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3WH5V@541000|Ruminococcaceae	186801|Clostridia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HGCANGJP_03355	476272.RUMHYD_01305	1.35e-73	221.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,3Y0FW@572511|Blautia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
HGCANGJP_03356	1235835.C814_02683	1.37e-83	246.0	COG1396@1|root,COG1396@2|Bacteria,1V331@1239|Firmicutes,24G00@186801|Clostridia,3WJJ9@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HGCANGJP_03357	478749.BRYFOR_06528	4.66e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_03358	1235835.C814_02685	2.68e-231	638.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3WI2K@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_03359	1235835.C814_02686	1.91e-151	426.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_03360	1235802.C823_01591	0.0	1476.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1VR4T@1239|Firmicutes,24XZV@186801|Clostridia,25ZFR@186806|Eubacteriaceae	186801|Clostridia	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
HGCANGJP_03361	1235835.C814_02695	3.58e-186	530.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WH9S@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
HGCANGJP_03362	411459.RUMOBE_00594	1.39e-66	204.0	COG0745@1|root,COG0745@2|Bacteria,1UVF6@1239|Firmicutes,25M0N@186801|Clostridia,3Y1TD@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
HGCANGJP_03363	411459.RUMOBE_00584	0.0	870.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3XZ6Y@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
HGCANGJP_03364	1121115.AXVN01000083_gene2461	3.51e-75	224.0	29VPK@1|root,30H70@2|Bacteria,1UH80@1239|Firmicutes,25PX8@186801|Clostridia,3Y1PB@572511|Blautia	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
HGCANGJP_03365	1121115.AXVN01000083_gene2460	1.34e-31	110.0	2FEN0@1|root,346MC@2|Bacteria,1VZFX@1239|Firmicutes,2532H@186801|Clostridia,3Y1ZK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03366	411459.RUMOBE_00571	8.55e-38	132.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3XZ4E@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
HGCANGJP_03367	457412.RSAG_00548	7.52e-87	255.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia,3WIH2@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_03368	457412.RSAG_00547	1.65e-112	323.0	COG1266@1|root,COG1266@2|Bacteria,1UR4V@1239|Firmicutes,258YQ@186801|Clostridia,3WP28@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
HGCANGJP_03369	457412.RSAG_00546	3.97e-227	625.0	29XH3@1|root,30J7Q@2|Bacteria,1U4GU@1239|Firmicutes,25NDN@186801|Clostridia,3WQT0@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF5300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5301
HGCANGJP_03370	1232443.BAIA02000032_gene1938	6.84e-185	514.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia,268RW@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
HGCANGJP_03371	411483.FAEPRAA2165_00850	1.53e-39	130.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia,3WJUG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03372	457412.RSAG_00543	2.97e-76	227.0	COG1349@1|root,COG1349@2|Bacteria,1V4EI@1239|Firmicutes,24HRM@186801|Clostridia,3WJ28@541000|Ruminococcaceae	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
HGCANGJP_03373	457412.RSAG_00542	3.48e-59	183.0	2B26K@1|root,31UPX@2|Bacteria,1V93Z@1239|Firmicutes,24JA0@186801|Clostridia,3WJCW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
HGCANGJP_03374	411459.RUMOBE_00635	7.96e-49	155.0	2CB7P@1|root,32X35@2|Bacteria,1VCII@1239|Firmicutes,24Q2Q@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4318
HGCANGJP_03375	457412.RSAG_00539	0.0	995.0	COG0507@1|root,COG1196@1|root,COG0507@2|Bacteria,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3WGDP@541000|Ruminococcaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
HGCANGJP_03376	411470.RUMGNA_00763	7.74e-146	411.0	COG0358@1|root,COG0358@2|Bacteria,1TRW1@1239|Firmicutes,249RY@186801|Clostridia,3XZM5@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
HGCANGJP_03377	742741.HMPREF9475_02749	0.0	901.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,21ZFP@1506553|Lachnoclostridium	186801|Clostridia	S	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
HGCANGJP_03378	1121115.AXVN01000053_gene1863	3.56e-47	151.0	2CCB2@1|root,30HYC@2|Bacteria,1W7AC@1239|Firmicutes,25N1I@186801|Clostridia,3Y25P@572511|Blautia	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
HGCANGJP_03379	742738.HMPREF9460_01140	1.27e-255	704.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,267WT@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
HGCANGJP_03380	457412.RSAG_00533	1.89e-114	327.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WIXC@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
HGCANGJP_03381	1121115.AXVN01000029_gene654	3.43e-234	643.0	2EWQA@1|root,33TE1@2|Bacteria,1VR3E@1239|Firmicutes,24ZHT@186801|Clostridia,3Y1M8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03382	1121115.AXVN01000029_gene653	2.56e-178	498.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3XZ9G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
HGCANGJP_03383	457412.RSAG_00530	4.68e-206	571.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGJI@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
HGCANGJP_03384	1121115.AXVN01000029_gene651	1.05e-225	623.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
HGCANGJP_03385	445973.CLOBAR_01114	0.0	1904.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,25T2H@186804|Peptostreptococcaceae	186801|Clostridia	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
HGCANGJP_03386	742765.HMPREF9457_02048	1.35e-62	191.0	2DVIT@1|root,33W14@2|Bacteria,1VW77@1239|Firmicutes,25AYS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03387	1504823.CCMM01000013_gene2508	3.85e-72	216.0	2BXTH@1|root,2ZZ52@2|Bacteria	2|Bacteria	S	COG NOG10998 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
HGCANGJP_03388	1121115.AXVN01000064_gene4029	9.82e-84	247.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24FW5@186801|Clostridia,3XZXI@572511|Blautia	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
HGCANGJP_03389	1256908.HMPREF0373_00445	2.36e-65	200.0	COG1396@1|root,COG1396@2|Bacteria,1VEGA@1239|Firmicutes,25EHT@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_03390	469596.HMPREF9488_01773	0.0	917.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,3VNUV@526524|Erysipelotrichia	1239|Firmicutes	D	Ftsk spoiiie family protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
HGCANGJP_03391	411459.RUMOBE_02873	8.56e-290	791.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,3XZ7X@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Rep_trans
HGCANGJP_03392	518637.EUBIFOR_01722	1.95e-21	84.0	2E3NJ@1|root,32YKN@2|Bacteria,1VIHR@1239|Firmicutes,3VRKR@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
HGCANGJP_03393	1235790.C805_01419	8.37e-42	137.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,25X23@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03394	658659.HMPREF0983_03984	1.35e-159	446.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,3VQNR@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03395	1232446.BAIE02000064_gene3614	2.03e-87	257.0	2CEH6@1|root,32RZW@2|Bacteria,1V3QW@1239|Firmicutes,25FN5@186801|Clostridia	186801|Clostridia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
HGCANGJP_03396	411461.DORFOR_00243	4.11e-28	102.0	2BS3G@1|root,2ZFNX@2|Bacteria,1W67Z@1239|Firmicutes,256B2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03397	469596.HMPREF9488_00500	4.75e-117	335.0	COG4734@1|root,COG4734@2|Bacteria,1UX6H@1239|Firmicutes,3VPP6@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
HGCANGJP_03398	1235790.C805_01415	4.4e-122	347.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25WNI@186806|Eubacteriaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
HGCANGJP_03399	537007.BLAHAN_06318	1.56e-100	297.0	COG0745@1|root,COG0745@2|Bacteria,1TT5H@1239|Firmicutes,24934@186801|Clostridia,3XZQ1@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
HGCANGJP_03400	411460.RUMTOR_00893	9.71e-150	429.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3XZ2K@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_03401	1499683.CCFF01000013_gene129	2.94e-38	142.0	2DPE9@1|root,331QW@2|Bacteria,1UP58@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
HGCANGJP_03402	1256908.HMPREF0373_00314	5.89e-106	317.0	COG5002@1|root,COG5002@2|Bacteria,1UIEP@1239|Firmicutes,25EK1@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
HGCANGJP_03403	665950.HMPREF1025_00443	2.03e-92	270.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,27NBR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
HGCANGJP_03404	665950.HMPREF1025_00444	0.0	1560.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia,27JV2@186928|unclassified Lachnospiraceae	186801|Clostridia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
HGCANGJP_03405	742723.HMPREF9477_00857	0.0	1234.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia,27KYQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03406	500632.CLONEX_02861	2.75e-245	673.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
HGCANGJP_03407	665950.HMPREF1025_00447	5.94e-208	576.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,27KG9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
HGCANGJP_03408	665950.HMPREF1025_00448	6.98e-78	232.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24I83@186801|Clostridia,27N00@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
HGCANGJP_03409	665950.HMPREF1025_00449	1.02e-178	500.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,27IKW@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
HGCANGJP_03411	500632.CLONEX_01159	1.81e-41	136.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03412	469596.HMPREF9488_00513	6.34e-94	274.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,3VPVS@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
HGCANGJP_03413	518637.EUBIFOR_01709	6.45e-51	160.0	2BNIM@1|root,32H78@2|Bacteria,1UHK4@1239|Firmicutes,3VR26@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
HGCANGJP_03414	1121115.AXVN01000137_gene1820	2.95e-170	475.0	29XPW@1|root,30JFI@2|Bacteria,1TTS7@1239|Firmicutes,257QZ@186801|Clostridia,3Y1YX@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
HGCANGJP_03415	658088.HMPREF0987_00515	1.62e-52	170.0	29AZ1@1|root,2ZXY1@2|Bacteria,1V4KY@1239|Firmicutes,24I9C@186801|Clostridia,27Q6H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03416	457412.RSAG_04689	1.47e-70	224.0	COG3385@1|root,COG3385@2|Bacteria,1UHBB@1239|Firmicutes,24ETX@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_03418	1235802.C823_03611	1.2e-61	196.0	2ENMS@1|root,33G93@2|Bacteria,1VMF6@1239|Firmicutes,24QEZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03419	515620.EUBELI_20662	3.27e-117	348.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,25WRV@186806|Eubacteriaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
HGCANGJP_03421	457412.RSAG_03146	0.0	1195.0	COG3209@1|root,COG3209@2|Bacteria,1TRJ1@1239|Firmicutes,24AU6@186801|Clostridia,3WHF3@541000|Ruminococcaceae	186801|Clostridia	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,LRR_5,Transglut_core
HGCANGJP_03422	457412.RSAG_03155	3.43e-163	531.0	COG2340@1|root,COG2340@2|Bacteria,1VQX9@1239|Firmicutes,24ZHD@186801|Clostridia	186801|Clostridia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03423	1121115.AXVN01000172_gene3991	2e-08	55.1	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
HGCANGJP_03424	411469.EUBHAL_02436	6.8e-85	253.0	29H8K@1|root,30465@2|Bacteria,1V42R@1239|Firmicutes,24H9W@186801|Clostridia,25YFS@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03425	1408312.JNJS01000002_gene104	2.41e-147	421.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
HGCANGJP_03426	457421.CBFG_04523	1.08e-254	712.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_03427	1121115.AXVN01000150_gene3970	1.42e-70	214.0	2EAKE@1|root,334P2@2|Bacteria,1VJFB@1239|Firmicutes,24RPC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03428	411469.EUBHAL_01615	9.68e-169	479.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
HGCANGJP_03429	1121115.AXVN01000122_gene2850	3.98e-72	217.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3Y02F@572511|Blautia	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
HGCANGJP_03430	1121115.AXVN01000122_gene2851	2.17e-140	396.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3XZEE@572511|Blautia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
HGCANGJP_03431	457412.RSAG_02634	1.1e-258	709.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia,3WIXJ@541000|Ruminococcaceae	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HGCANGJP_03432	1121115.AXVN01000122_gene2853	1.24e-148	419.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
HGCANGJP_03433	1121115.AXVN01000122_gene2854	9.51e-202	558.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
HGCANGJP_03434	1121115.AXVN01000122_gene2855	1.38e-222	613.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZRN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
HGCANGJP_03435	1121115.AXVN01000122_gene2856	4.45e-128	364.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,3Y027@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
HGCANGJP_03436	1121115.AXVN01000122_gene2857	3.27e-284	781.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,3XZF7@572511|Blautia	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
HGCANGJP_03437	1121115.AXVN01000122_gene2858	2.19e-278	764.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,3XYH0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03438	1121115.AXVN01000122_gene2859	4.42e-154	434.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24SVX@186801|Clostridia,3Y00H@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
HGCANGJP_03439	1121115.AXVN01000001_gene1091	1.2e-93	275.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24H0D@186801|Clostridia,3Y03W@572511|Blautia	186801|Clostridia	S	conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
HGCANGJP_03441	1203606.HMPREF1526_01783	3.82e-199	556.0	COG2207@1|root,COG2207@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,36GRU@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
HGCANGJP_03442	1121115.AXVN01000001_gene1090	4.13e-130	370.0	2BY0N@1|root,30WA4@2|Bacteria,1W7CN@1239|Firmicutes,25MGX@186801|Clostridia,3Y1Y3@572511|Blautia	186801|Clostridia	S	Hypothetical bacterial integral membrane protein (Trep_Strep)	-	-	-	-	-	-	-	-	-	-	-	-	Trep_Strep
HGCANGJP_03443	1121115.AXVN01000001_gene1089	1.12e-163	459.0	COG0619@1|root,COG0619@2|Bacteria,1UVFB@1239|Firmicutes,25MDZ@186801|Clostridia,3Y0VN@572511|Blautia	186801|Clostridia	P	COG COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
HGCANGJP_03444	1121115.AXVN01000001_gene1088	0.0	977.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,3Y00T@572511|Blautia	186801|Clostridia	G	COG COG1122 ABC-type cobalt transport system, ATPase component	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
HGCANGJP_03445	552396.HMPREF0863_00463	0.0	1099.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VPBW@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
HGCANGJP_03446	552396.HMPREF0863_00462	0.0	1072.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VP61@526524|Erysipelotrichia	526524|Erysipelotrichia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
HGCANGJP_03447	411459.RUMOBE_03494	1.16e-127	366.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,3XYII@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	baiA	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
HGCANGJP_03448	457412.RSAG_03422	2.63e-241	664.0	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,3WN05@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
HGCANGJP_03449	457412.RSAG_03423	2.4e-182	507.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
HGCANGJP_03450	457412.RSAG_04560	2.19e-84	248.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HGCANGJP_03451	585394.RHOM_15045	2.78e-13	65.5	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia	186801|Clostridia	O	Antioxidant, AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
HGCANGJP_03452	457412.RSAG_03425	7.5e-23	89.4	2C9RV@1|root,32TYA@2|Bacteria,1VDD3@1239|Firmicutes,24T6T@186801|Clostridia,3WR16@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03453	457412.RSAG_03426	2.3e-96	280.0	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03454	457412.RSAG_03427	2.87e-43	140.0	2D2HR@1|root,32TCU@2|Bacteria,1VA21@1239|Firmicutes,24MT0@186801|Clostridia	186801|Clostridia	S	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
HGCANGJP_03455	457412.RSAG_03428	2.38e-99	288.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,3WKH1@541000|Ruminococcaceae	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
HGCANGJP_03456	457412.RSAG_03429	4.95e-37	124.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,3WKG3@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rd	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
HGCANGJP_03457	457412.RSAG_03430	2e-90	264.0	28PBY@1|root,2ZC4G@2|Bacteria,1V2G3@1239|Firmicutes,24HDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03458	457412.RSAG_03431	1.6e-133	378.0	28KSD@1|root,2ZA9R@2|Bacteria,1UZZ4@1239|Firmicutes,249ZS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03459	457412.RSAG_03432	5.55e-54	168.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,24QMD@186801|Clostridia,3WM6E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03460	457412.RSAG_04562	4.07e-43	140.0	COG1974@1|root,COG1974@2|Bacteria,1VDZS@1239|Firmicutes,25E0Q@186801|Clostridia	186801|Clostridia	L	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind
HGCANGJP_03461	457412.RSAG_03433	1.45e-150	423.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
HGCANGJP_03462	457412.RSAG_03434	5e-124	353.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
HGCANGJP_03463	1121115.AXVN01000104_gene854	2.37e-110	317.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
HGCANGJP_03464	1121115.AXVN01000123_gene2860	1.95e-160	450.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,3XZIA@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
HGCANGJP_03465	457412.RSAG_01521	9.07e-211	584.0	COG1172@1|root,COG1172@2|Bacteria,1U0FI@1239|Firmicutes,24B5S@186801|Clostridia,3WPSA@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
HGCANGJP_03466	457412.RSAG_01522	0.0	971.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WGJM@541000|Ruminococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
HGCANGJP_03467	457412.RSAG_01523	3.05e-210	582.0	COG1172@1|root,COG1172@2|Bacteria,1UVPQ@1239|Firmicutes,25MGQ@186801|Clostridia,3WPXD@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
HGCANGJP_03468	457412.RSAG_01524	4.58e-269	737.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K03406,ko:K10439	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	GntR,Peripla_BP_3,Peripla_BP_4
HGCANGJP_03469	457412.RSAG_01525	0.0	1020.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,3WH94@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
HGCANGJP_03470	411459.RUMOBE_03759	1.51e-18	80.9	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3Y0EM@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_03471	457412.RSAG_01904	9.24e-119	339.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,3WK3U@541000|Ruminococcaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
HGCANGJP_03472	457412.RSAG_01903	5.62e-132	374.0	COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,24HX1@186801|Clostridia,3WK9W@541000|Ruminococcaceae	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
HGCANGJP_03473	457412.RSAG_01901	1.27e-72	218.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,3WHBJ@541000|Ruminococcaceae	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
HGCANGJP_03476	1121115.AXVN01000078_gene2834	2.74e-195	544.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3XYRQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
HGCANGJP_03481	457412.RSAG_01899	2.67e-43	140.0	COG2155@1|root,COG2155@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF378)	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
HGCANGJP_03482	457412.RSAG_01898	9.21e-228	630.0	2E2H9@1|root,32XM9@2|Bacteria,1VC5F@1239|Firmicutes,24PWJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4878,DUF5067
HGCANGJP_03483	457412.RSAG_01897	2.59e-229	630.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
HGCANGJP_03484	457412.RSAG_01912	2.3e-297	810.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,3WIAE@541000|Ruminococcaceae	186801|Clostridia	L	PFAM Transposase, Mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
HGCANGJP_03485	457412.RSAG_01910	2.15e-200	555.0	COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,24931@186801|Clostridia,3WIEJ@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	licT	-	-	ko:K03488	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
HGCANGJP_03486	457412.RSAG_01909	0.0	1166.0	COG1263@1|root,COG2190@1|root,COG1263@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3WG8J@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02756,ko:K02757,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269,M00271	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.11,4.A.1.2.12,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HGCANGJP_03487	457412.RSAG_01908	0.0	1002.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WIB4@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HGCANGJP_03489	457412.RSAG_01906	3.59e-66	206.0	2FCDN@1|root,344H7@2|Bacteria,1W31R@1239|Firmicutes,256SW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03490	457412.RSAG_03154	3.19e-94	291.0	2953W@1|root,2ZSGJ@2|Bacteria,1W5UM@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03491	457412.RSAG_00997	7.71e-183	509.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WIVB@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
HGCANGJP_03492	457412.RSAG_00995	4.8e-313	851.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WH66@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
HGCANGJP_03493	1121115.AXVN01000172_gene3991	8.97e-292	797.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
HGCANGJP_03494	457412.RSAG_00784	9.11e-274	798.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
HGCANGJP_03495	1121115.AXVN01000006_gene2165	0.0	1303.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3XYKA@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
HGCANGJP_03496	1121115.AXVN01000006_gene2166	4e-155	435.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,3XZV5@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
HGCANGJP_03497	1121115.AXVN01000006_gene2167	1.41e-201	556.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,3XYRY@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
HGCANGJP_03498	483218.BACPEC_00280	2.9e-150	423.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,2689T@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
HGCANGJP_03499	457412.RSAG_01439	0.0	1665.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WH8W@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
HGCANGJP_03500	1121115.AXVN01000010_gene2768	1.69e-199	553.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,24D1J@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
HGCANGJP_03501	1121115.AXVN01000010_gene2767	1.35e-140	397.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3XZ4U@572511|Blautia	186801|Clostridia	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
HGCANGJP_03502	1121115.AXVN01000010_gene2766	6.1e-160	448.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,24ETM@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
HGCANGJP_03503	1121115.AXVN01000010_gene2765	1.1e-113	325.0	COG2371@1|root,COG2371@2|Bacteria,1V7SB@1239|Firmicutes,25DT7@186801|Clostridia	186801|Clostridia	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
HGCANGJP_03504	1121115.AXVN01000010_gene2764	3.75e-119	340.0	2DC0F@1|root,2ZC7C@2|Bacteria,1UPV2@1239|Firmicutes,25HPJ@186801|Clostridia	186801|Clostridia	S	AmiS/UreI family transporter	-	-	-	ko:K03191	ko05120,map05120	-	-	-	ko00000,ko00001,ko02000	1.A.29.1.3,1.A.29.1.4,1.A.29.1.5	-	-	AmiS_UreI
HGCANGJP_03505	457412.RSAG_01445	0.0	1148.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
HGCANGJP_03506	1121115.AXVN01000010_gene2762	3.91e-82	243.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,24N65@186801|Clostridia	186801|Clostridia	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
HGCANGJP_03507	1121115.AXVN01000010_gene2761	1.77e-62	191.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,24MN2@186801|Clostridia	186801|Clostridia	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
HGCANGJP_03508	457412.RSAG_01447	3.01e-297	809.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,3WN9Q@541000|Ruminococcaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
HGCANGJP_03510	457412.RSAG_01448	0.0	1420.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,3WH88@541000|Ruminococcaceae	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
HGCANGJP_03511	457412.RSAG_01449	9.09e-314	856.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_03512	457412.RSAG_01450	0.0	1152.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WGUV@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
HGCANGJP_03513	537007.BLAHAN_04440	5.72e-242	674.0	2CBQ9@1|root,2Z7UY@2|Bacteria,1V0C0@1239|Firmicutes,24EZN@186801|Clostridia,3XZGE@572511|Blautia	186801|Clostridia	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
HGCANGJP_03514	476272.RUMHYD_02199	4.88e-263	731.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XYR0@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
HGCANGJP_03515	742765.HMPREF9457_02932	1.6e-155	441.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_03516	742765.HMPREF9457_02931	1.97e-169	478.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
HGCANGJP_03517	742765.HMPREF9457_02930	1.84e-232	647.0	COG1653@1|root,COG1653@2|Bacteria,1UVGF@1239|Firmicutes,25MFW@186801|Clostridia,27WU0@189330|Dorea	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
HGCANGJP_03518	457421.CBFG_01818	4.43e-150	431.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HGCANGJP_03519	1121115.AXVN01000120_gene2843	2.42e-105	304.0	COG1633@1|root,COG1633@2|Bacteria,1V72Y@1239|Firmicutes,24JY4@186801|Clostridia,3Y12U@572511|Blautia	186801|Clostridia	S	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F,Rubrerythrin
HGCANGJP_03520	457412.RSAG_01452	5.48e-315	859.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
HGCANGJP_03521	457412.RSAG_01453	4.46e-94	275.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia,3WJPG@541000|Ruminococcaceae	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
HGCANGJP_03522	1121115.AXVN01000069_gene2320	1.61e-64	197.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3Y0P1@572511|Blautia	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
HGCANGJP_03523	1121115.AXVN01000069_gene2319	1.49e-138	393.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3Y2B8@572511|Blautia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
HGCANGJP_03524	1121115.AXVN01000069_gene2318	9.09e-298	814.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,3XZ6V@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	mleN_2	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
HGCANGJP_03525	1121115.AXVN01000069_gene2317	1.65e-193	538.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3XZ72@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
HGCANGJP_03526	1121115.AXVN01000069_gene2316	7.45e-150	422.0	29XH4@1|root,30J7T@2|Bacteria,1UVPT@1239|Firmicutes,2503Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03527	1121115.AXVN01000069_gene2315	1.16e-118	339.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3Y0D0@572511|Blautia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
HGCANGJP_03529	1121115.AXVN01000069_gene2314	0.0	1075.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y11F@572511|Blautia	186801|Clostridia	M	non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
HGCANGJP_03531	1121115.AXVN01000069_gene2313	0.0	1004.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3XYQ2@572511|Blautia	186801|Clostridia	G	COG COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase	bglA	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
HGCANGJP_03532	1121115.AXVN01000069_gene2312	0.0	1218.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3XZPH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
HGCANGJP_03533	1121115.AXVN01000069_gene2311	2.49e-193	537.0	COG1737@1|root,COG1737@2|Bacteria,1TUHQ@1239|Firmicutes,25CE7@186801|Clostridia	186801|Clostridia	K	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
HGCANGJP_03534	1121115.AXVN01000069_gene2309	0.0	1419.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3XZ5S@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
HGCANGJP_03535	1121115.AXVN01000069_gene2308	0.0	1181.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1V2W6@1239|Firmicutes,249GG@186801|Clostridia	186801|Clostridia	FG	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	5_nucleotid_C,SBP_bac_8,TAT_signal
HGCANGJP_03536	1121115.AXVN01000069_gene2307	2.26e-215	595.0	COG2253@1|root,COG2253@2|Bacteria,1TQ54@1239|Firmicutes,24CDZ@186801|Clostridia	186801|Clostridia	V	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
HGCANGJP_03537	1121115.AXVN01000069_gene2306	1.72e-127	363.0	COG5340@1|root,COG5340@2|Bacteria,1V3P6@1239|Firmicutes,24HEC@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03538	457412.RSAG_01461	3.96e-207	615.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,3WJQR@541000|Ruminococcaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03539	1121115.AXVN01000065_gene689	1.78e-147	415.0	2DUMV@1|root,33RB2@2|Bacteria,1VSTK@1239|Firmicutes,259KM@186801|Clostridia,3Y0VY@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
HGCANGJP_03540	1121115.AXVN01000065_gene688	2.94e-209	580.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3XZSP@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
HGCANGJP_03541	1121115.AXVN01000065_gene686	5.59e-78	232.0	COG0239@1|root,COG0239@2|Bacteria,1TTU1@1239|Firmicutes,259CY@186801|Clostridia,3Y0J4@572511|Blautia	186801|Clostridia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
HGCANGJP_03542	457412.RSAG_01468	8.44e-111	318.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3WJKY@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 8.96	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
HGCANGJP_03543	1121115.AXVN01000065_gene684	1.82e-152	429.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,3XZ3K@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
HGCANGJP_03545	1121115.AXVN01000065_gene682	1.34e-209	581.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3Y0WW@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_03546	411489.CLOL250_01660	4.35e-65	199.0	295RU@1|root,30FMW@2|Bacteria,1UE97@1239|Firmicutes,25J4D@186801|Clostridia,36T0W@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
HGCANGJP_03547	1121115.AXVN01000065_gene680	8.86e-35	119.0	2CHQ1@1|root,3240C@2|Bacteria,1UQE2@1239|Firmicutes,25855@186801|Clostridia,3Y1Z3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03548	411489.CLOL250_01657	2.73e-75	226.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,36VZ3@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
HGCANGJP_03549	411489.CLOL250_01656	9.07e-268	743.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,36KE8@31979|Clostridiaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
HGCANGJP_03550	411489.CLOL250_01655	1.69e-51	162.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,36TY6@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
HGCANGJP_03551	411489.CLOL250_01654	4.9e-42	138.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,36T49@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03552	411489.CLOL250_01653	1.23e-230	635.0	COG1066@1|root,COG1066@2|Bacteria,1UIA9@1239|Firmicutes,25EF9@186801|Clostridia,36UNR@31979|Clostridiaceae	186801|Clostridia	O	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
HGCANGJP_03553	411489.CLOL250_01652	2.1e-289	790.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36E23@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
HGCANGJP_03554	411489.CLOL250_01651	2.33e-34	117.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,36PEI@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03555	411489.CLOL250_01650	5.19e-141	399.0	COG1396@1|root,COG1396@2|Bacteria,1TQ4Q@1239|Firmicutes,25FKR@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
HGCANGJP_03556	1121115.AXVN01000065_gene678	1.86e-288	787.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
HGCANGJP_03557	1121115.AXVN01000065_gene677	0.0	1407.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3XYNI@572511|Blautia	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
HGCANGJP_03558	457412.RSAG_01491	6.62e-105	303.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
HGCANGJP_03559	1121115.AXVN01000065_gene675	4.34e-90	264.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3XZTZ@572511|Blautia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
HGCANGJP_03560	457412.RSAG_01493	2.67e-228	630.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
HGCANGJP_03561	457412.RSAG_01494	2.02e-210	587.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
HGCANGJP_03562	33035.JPJF01000008_gene1192	6.68e-06	48.1	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ8Q@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
HGCANGJP_03563	457412.RSAG_01496	4.84e-297	810.0	2CF3U@1|root,33TFS@2|Bacteria,1VS98@1239|Firmicutes,24YVZ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03564	1121115.AXVN01000068_gene3396	6.18e-199	550.0	COG0631@1|root,COG0631@2|Bacteria,1VTG4@1239|Firmicutes,257XD@186801|Clostridia,3Y03T@572511|Blautia	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
HGCANGJP_03565	457412.RSAG_01498	0.0	1161.0	COG0515@1|root,COG0515@2|Bacteria,1V2ZP@1239|Firmicutes,24G58@186801|Clostridia,3WIKP@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5050,PASTA,Pkinase,SH3_3
HGCANGJP_03566	457412.RSAG_01499	0.0	2381.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
HGCANGJP_03567	1121115.AXVN01000068_gene3399	0.0	2521.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3XYKN@572511|Blautia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
HGCANGJP_03568	1121115.AXVN01000068_gene3400	0.0	1299.0	COG5434@1|root,COG5434@2|Bacteria,1V8MX@1239|Firmicutes,257MV@186801|Clostridia,3Y1ZG@572511|Blautia	186801|Clostridia	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
HGCANGJP_03569	1121115.AXVN01000068_gene3401	1.58e-69	211.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
HGCANGJP_03570	1121115.AXVN01000068_gene3402	6.98e-110	317.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3XZVD@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
HGCANGJP_03571	1121115.AXVN01000068_gene3403	6.96e-151	424.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3XZJ9@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
HGCANGJP_03572	1121115.AXVN01000068_gene3404	9.69e-42	136.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,3Y0J2@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
HGCANGJP_03573	457412.RSAG_01506	6.88e-257	705.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WIJZ@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
## 3394 queries scanned
## Total time (seconds): 227.29992246627808
## Rate: 14.93 q/s