LOCUS       c00043_gnlPro..         8393 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KJMJODMD_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 05:17:04
            Original ID  :: gnl|Prokka|KJMJODMD_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8393
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8393
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1036:4703]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1037..4703
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     protocluster    1..8393
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1036:7882]"
                     /cutoff="10000"
                     /detection_rule="((cds(Pyr_redox_2 and Oxidored_FMN) or
                     baiCD or baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C,
                     Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2,
                     Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central,
                     Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD,
                     IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]))"
                     /neighbourhood="10000"
                     /product="Flavoenzyme_AA_peptides_catabolism"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      1037..7882
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="((cds(Pyr_redox_2 and Oxidored_FMN) or
                     baiCD or baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C,
                     Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2,
                     Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central,
                     Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD,
                     IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]))"
                     /neighbourhood="10000"
                     /product="Flavoenzyme_AA_peptides_catabolism"
                     /protocluster_number="2"
     cand_cluster    1..8393
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((cds(Pyr_redox_2 and Oxidored_FMN) or
                     baiCD or baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C,
                     Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2,
                     Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central,
                     Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD,
                     IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]))"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="chemical_hybrid"
                     /product="Flavoenzyme_AA_peptides_catabolism"
                     /product="Others_HGD_unassigned"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8393
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Flavoenzyme_AA_peptides_catabolism"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="((cds(Pyr_redox_2 and Oxidored_FMN) or baiCD or
                     baiH) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase,
                     BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2,
                     Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central,
                     Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD,
                     IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]))"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             260..1021
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_1"
                     /sec_met_domain="CbiA (E-value: 2e-14, bitscore: 42.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEAKIIAVAGKGGVGKTSVSAMIVRILTRKYPDARILAIDADPA
                     VGLATALGVTVERTMDDIRKAIVENVQKGQKKEAVECLGEARNLMFDALEEQEGFAFLA
                     IGRPEAAGCYCAVNAYLKEVITTMAEQFDFVVIDGEAGIEQINRRVMERVTHLILITDP
                     SQKGLQVVKTIKKVADELVMYEACGVLVNRLPDVKMLKFLDLEEIPYLGAVGQDSSLTE
                     FDLKGENILNLPDSSLLAAGVKEALEKLHIV"
     CDS             1037..2242
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Flavoenzyme_AA_peptides_catabolism: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_2"
                     /sec_met_domain="HGD-D (E-value: 3.6e-66, bitscore: 213.0,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDLKHLFYFENLLQEANNELVQQAKKEGRLAIGYTCFHMPEVLL
                     NVDRCFSLRMRAPRTGSLEIATYYMSNYTCEYCRALLERAVEGGYNFLDGIAAVDACAQ
                     MNRSMENILVQKLIPGDKFFMSHVDVPYKVTEHGVEHQAEQIRTKVFRKLEENYGVDTS
                     DESIRKAVEEHNEICRIITEIGEYRKKENPPVTGYEFHILNLITYVCPKYLILDRLRET
                     LEEIRTREPDEKKNYRARVVIAGSEIDDPEFTKLVEEAGALVVADRFCFGSFPGRQEIQ
                     LGEEKDVLKAVCRRYMEDSQCARYMSHEKIQERRDFVRKLYEDYHADGIIYEQLKFCDY
                     WGYERALVSHIMQEEYELPVLSVDRPYRAGSSGQMRTRIQAFVERMEIKKIQNRRGGSL
                     HG"
     CDS             2235..3881
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Flavoenzyme_AA_peptides_catabolism: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_3"
                     /sec_met_domain="HGD-D (E-value: 1.5e-37, bitscore: 118.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKIEELLEKGKEMKTQGQKVLKKERKTITRAIHAWKDMDHHKG
                     DVHTGELTTAFREWRGVKDTAYDFAKWLQVWGDMSLMIMKNPVGSVKGLWKYRWFSSYL
                     QTPMFIDAQLVGLRGPQLRIAREHMRMIVQFCTRLLENTFKADENLNGPNALSDKIVLF
                     DEMMPIHIMAGFPNLIGMPSQMAPVYITSLLDQQMQVHYLDETENYGLPADVCPLPSAE
                     AGCGIAGDYPIFGKCYITSSMPCDGSVMTNIFQDRYFKLPTYPLTLPVRYLDEQAVDYA
                     VEEIKGMIHFIEENTGETFDWDAYFEAMERYNKETEYEQEKWDVNQTEYPQITGSILAV
                     YRELSYMADAGRDPRFLKTDERVNKIMMKAYREKRPCAKEMRHRAVVWSCPAHYYANFG
                     NWAQQCWGINVLIDMESMMSMKFIDTEDKEESLKDIAWTYERMAMRKHTNGGYANVLDE
                     LWKVCEEFHADMVLMYSHISCKTMAGLQGLFDDQARERGIRFIWVEHDLMDPRTVSRRH
                     MRESVNRYMRTVMHEEPVDPSLEDFDDEKEW"
     CDS             3909..4703
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Flavoenzyme_AA_peptides_catabolism: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_4"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.2e-64, bitscore:
                     207.2, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYYGGCDVGSTYTKCVILDEDGNIAAHTTIKSKINPSESSVIA
                     MDETMKQVEELNSPKDLAYLIGTGYGRNKVPFADENISEISCHAMGVHVTNPKVSAIID
                     IGGQDVKGIAIDTDGTVKNFAMNDKCAAGTGRFFETMANAFEMSLEDFSNLSLSAKNVI
                     PITAQCTVFAESEVITLVGEGKARDEIAAGIELAVAKRCFVMAKKAGVTDRITLTGGCA
                     KNAGLKKAIEHVLKVKVIDLDVDPQLMGALGAAEYARQKGRR"
     CDS             4717..4890
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MKKEKHGCILKKILAVSGIAVVLLFIIYIFNLDVKLIGFVYKLLG
                     KHYDDMDRERKL"
     CDS             4890..5603
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MNIQDQIIRDTRSLLKNIPPVCFPYDSQNCAPARKDSQVLLLKET
                     AFELGGREKKSAAYICISSEPGIVGENSTLLYGPDLGQIKGPLSYARITFAETEDIGED
                     DRAYHICKDIDLIKYSVFPEGFMVRASSMEAREQVRVGKKAVKDGLSFAQIGNLFIRKY
                     LEYPKVRAVQVLFITGETADFKGLGRLAEKNKMITKALNKIMEKADKECSTCGLKEICD
                     EVEGLRKMHFQNRKR"
     CDS             5609..7882
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Flavoenzyme_AA_peptides_catabolism: baiH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_7"
                     /sec_met_domain="baiH (E-value: 5.2e-106, bitscore: 344.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKTDKIVQKLVDSYGSWVQEEKENCPGHCAVMSKELYPYDAIFSP
                     IRVNRITLKNRVVMAPMGNLNMCEENGRPSDKMLQYFFARAKGGTGLLTTGLIPISHGI
                     DNTVTEPGKLSFFPRIDRSRTVFSGWRDLAQGVHAYGSRIFIQLTPGLGRVGPPQCVIN
                     EMKLPCSASLNPNFYIPELPCLPLTDLALHKIIKNGGQAASDAKTAGLDGVYLHGHEGY
                     LLDQLTNPAFNRRKAGRYAYWQNFGLDLVREIRKRVGDSYPIMYRIDLSLALNETYKER
                     MESVRSLKKFTNGRTIYDTLRYMENLVKAGVDMFDVDLGCYDNWWLPHPPAGMPAGCFL
                     DISRIAKKYFKTREVKTNAGLEVPVVAVGKLGYPDLAEKAIRDGMCDLVMLGRPLLADP
                     DWCRKAYAGEVERIRPCIGCQEGCINEFVEGGHPQCAVNPRTGFEDVIPETLPRAENTK
                     KIAVVGAGPSGMQFALTASARGHQVTLIEREKILGGKVVPGSRPKIKFDFKNYLEYLIR
                     EVHLAEEKGGLTVCTGVEADTQWLKEQNFDAIVYNIGTTSVVPKIPGVDQADWVQATDL
                     LCEPEKLGKAKKTVVIGGGVVGCETAYWLKYEKGCDVTVVEMLPYIMSGACTANRYHLI
                     HYMEKAGVQLLNCAKVTGFTKGSVQIEKNISKGVPDPYNTWQPQLPENIANPLAKKIGP
                     ETENQELPADLVIFAMGGRPDESLYLEGLRLHAAKELYNIGDSFSGGRVLEASRAAYRL
                     AREI"
ORIGIN
        1 agagctttgc ctccactgct gttttacgga gaacttctat tttttctgtc tggcgtggag
       61 ggaatggata tctatccatt aaattgcatg aaaatacatt ttattgacgt tacgaaaata
      121 atattttgaa atacaaacta ataaatacag aattaacaga aaaatataat gaaaataagc
      181 gaattgcatt gactatattt ggcggaatct ctataataaa aatgacagtg aagcgtgata
      241 acaggaggtg agaaggcgta tgggagaagc aaagatcatt gccgtagcag gaaaaggagg
      301 tgtgggaaag acatcggttt ccgccatgat cgtccgtatc ctgacacgga agtatccgga
      361 tgccaggata ctggccattg atgcggaccc ggctgtaggg cttgccacag cactgggggt
      421 tactgtggag agaaccatgg atgatatacg gaaggcaatt gttgagaatg tacagaaagg
      481 tcagaaaaag gaggccgtgg aatgtctggg agaggccaga aatttaatgt ttgatgctct
      541 ggaggagcag gaaggctttg catttctggc catcggtcga ccggaggctg cagggtgcta
      601 ctgtgcggta aatgcgtatc tgaaagaagt catcaccaca atggcagagc agtttgactt
      661 tgtggtgatc gacggtgagg cgggcattga acagatcaac cgccgtgtca tggagcgtgt
      721 gacccatctg atcctgatca cagacccaag ccagaaaggg ctgcaggtgg tgaaaaccat
      781 aaagaaggtg gcagatgaac tggttatgta tgaagcctgc ggtgtgctgg taaaccgtct
      841 gccggatgtg aaaatgctta agttcctgga tcttgaggag ataccgtatc tgggagccgt
      901 gggacaggac agcagcctta cggagtttga tttaaagggg gagaatattt taaacctgcc
      961 tgacagttcc ctgctggcag caggtgtaaa ggaggcactt gaaaaactgc atattgtatg
     1021 aggaggtgtg aaccgggtga aagatttaaa gcatttgttt tactttgaaa atctgctcca
     1081 ggaggcaaac aatgaactgg tgcagcaggc aaaaaaggag ggcagactgg ccatcggata
     1141 tacctgtttc catatgccgg aggttctgtt aaatgtggac cgctgttttt ctctcaggat
     1201 gagagcgccc aggacaggtt ccctggagat tgccacatat tacatgtcaa actacacctg
     1261 tgagtattgc cgcgcccttt tggagcgggc agtggagggc ggatacaatt tcctggacgg
     1321 catcgcggcg gtggacgcct gcgcccagat gaaccgttcc atggagaata ttctggtgca
     1381 gaagctgata ccgggtgaca aattctttat gtcccatgtg gatgtgccct ataaggtgac
     1441 agaacacgga gtggagcacc aggcagaaca gatccggaca aaagtgttcc gaaagctgga
     1501 ggaaaattat ggagtggata cctcagacga atccataaga aaagccgtgg aagagcacaa
     1561 tgagatctgc cgtattatta cagagatcgg ggaataccga aagaaggaaa atccgccagt
     1621 cactggttac gagttccata tcctgaacct gatcacatat gtctgtccga aatatctgat
     1681 cctggacaga ctccgtgaga ctctggagga gatacggacc agagaaccgg atgaaaaaaa
     1741 gaactacagg gccagagttg tcattgccgg aagtgagatt gacgatccag aatttacaaa
     1801 gctggtggag gaggcaggtg cccttgtggt ggcagaccgc ttctgttttg gctcctttcc
     1861 gggaagacag gagattcagc ttggggagga aaaagacgta ttaaaggctg tgtgccgcag
     1921 atatatggag gacagccagt gtgcccgcta tatgagccat gagaagatcc aggaaaggcg
     1981 ggattttgtg agaaagctct atgaggatta ccatgcggac ggcatcatct atgaacagtt
     2041 aaaattctgc gactactggg gctatgagag ggctttggtc agccatatca tgcaggagga
     2101 atatgaactt ccggtgctgt ctgtggacag gccttacagg gcaggttcct ccggacagat
     2161 gcgtaccagg atacaggctt ttgtggaacg gatggagatc aagaagatcc agaaccggag
     2221 aggaggcagc ctccatggat aaaaaaatcg aagaactgct ggaaaaagga aaagaaatga
     2281 aaacgcaggg acagaaggtc ctgaaaaaag agagaaagac catcaccaga gccattcatg
     2341 cctggaagga tatggaccat cacaagggcg acgtccatac cggtgagctg accacagcat
     2401 tcagggagtg gagaggggta aaggacactg cctacgactt tgcaaaatgg ctgcaggtgt
     2461 ggggggatat gagcctcatg atcatgaaaa atccagtagg ctctgtaaaa gggctgtgga
     2521 aatacagatg gttcagttcc tatctgcaga cgcccatgtt tattgatgcc cagctcgtag
     2581 ggcttagggg gccgcagctt cgcatcgcca gggagcatat gaggatgatc gtccaattct
     2641 gtacccgcct gctggaaaat accttcaagg cagacgagaa tctgaacggg ccaaatgccc
     2701 tgagtgacaa gattgtactt tttgacgaga tgatgcccat acatatcatg gcgggcttcc
     2761 ctaatctcat tggcatgccc tcccagatgg cacctgtata catcacctcc cttctggacc
     2821 agcagatgca ggttcattat ctggatgaga cggaaaacta tgggcttccg gcagatgtct
     2881 gccctcttcc ctcagcggag gccgggtgcg ggatcgcggg ggattacccc atatttggca
     2941 aatgctatat aaccagcagt atgccctgcg acggaagtgt tatgacaaat atattccagg
     3001 acagatattt taagcttccc acttatcctc tgacgcttcc ggtgcgttac ctggatgaac
     3061 aggcagtgga ctacgcggtg gaagagatca agggaatgat ccattttatc gaggaaaaca
     3121 caggggagac atttgactgg gatgcttatt ttgaggccat ggaaaggtac aataaggaga
     3181 cagaatatga gcaggagaaa tgggatgtga atcagacgga atatcctcag atcacaggtt
     3241 ctatcctggc tgtttaccgg gaactcagct acatggcaga cgcgggccgg gatcccagat
     3301 tcctgaaaac agatgagaga gtgaacaaga tcatgatgaa ggcctatagg gagaagagac
     3361 cctgtgcaaa agagatgcgg caccgggctg tggtatggtc ttgtccggct cactattatg
     3421 ccaacttcgg caattgggca cagcagtgct ggggcattaa cgtgctcatt gatatggaga
     3481 gcatgatgtc catgaagttt attgatacag aggacaaaga ggagtcctta aaggatattg
     3541 cgtggacata tgagcgcatg gccatgagga agcataccaa tggcggctat gccaatgtgc
     3601 tggatgagct ttggaaggtc tgtgaggaat tccacgcgga tatggtcctt atgtacagcc
     3661 acatttcctg caagaccatg gcagggcttc agggattgtt tgacgaccag gcaagggaac
     3721 ggggaatccg ttttatctgg gtggaacacg atctgatgga ccccagaacg gtctccaggc
     3781 gccatatgag agaatctgtg aaccgttata tgcgcacagt catgcatgag gaacccgtgg
     3841 acccgtcact ggaagatttt gacgatgaga aggaatggta gatacccggg aaaaggaggt
     3901 tgcaggcaat gaaaaaatat tatggaggat gtgacgttgg atccacctat accaagtgtg
     3961 tgatcctgga tgaagatgga aacatagctg cccacacaac gataaaaagt aagatcaatc
     4021 catcggaaag ctctgtgatc gctatggatg aaaccatgaa acaggtggaa gagctgaaca
     4081 gtcccaagga tctggcttat ctgatcggaa ccggctacgg cagaaataaa gtgccttttg
     4141 cagatgaaaa catttcagag ataagctgtc atgccatggg ggtccatgtg acgaacccga
     4201 aggtgagcgc catcattgat atcggcggac aggatgtgaa gggcatcgcc atagacacag
     4261 acggaacggt gaaaaacttt gccatgaatg acaagtgtgc tgccggtacg ggaagatttt
     4321 ttgagaccat ggcaaatgcc tttgaaatgt cactggagga tttttcaaac ctgtctttaa
     4381 gcgcaaaaaa tgtcatcccc atcactgccc agtgcacagt atttgcggag agtgaagtga
     4441 tcacactggt gggtgaggga aaggccaggg atgagatcgc cgcggggatt gagctggcag
     4501 tggcaaagag atgctttgtc atggcaaaga aggccggggt cacggacagg atcaccctga
     4561 ccgggggctg tgccaagaat gcagggctta aaaaggccat tgagcatgtc ctgaaggtga
     4621 aagtcataga tctggatgtg gacccgcagc taatgggcgc tctgggggca gcggaatatg
     4681 cccgtcagaa gggaagaaga taaaggaggg atctctatga agaaagagaa gcacggatgc
     4741 atcctgaaaa agatactggc agtaagcgga atcgcagtcg ttttgttatt tatcatttat
     4801 atctttaatc tggatgtgaa gcttattgga tttgtctaca agctgctggg aaaacattat
     4861 gatgatatgg acagggagag aaaactttaa tgaacataca ggaccagatc atacgggata
     4921 cccgttctct gcttaagaat atcccgccgg tctgttttcc ctatgactcc caaaactgcg
     4981 cgccagcccg gaaggacagc caggtgctgc ttttgaaaga gacagctttt gagcttggag
     5041 gcagagagaa aaaaagtgcg gcgtacatct gcatctcttc agaaccgggt atcgtgggag
     5101 aaaattccac tctgctttac ggcccggatc tggggcagat aaaaggccct ctctcctatg
     5161 ccaggatcac atttgcagag acagaagaca ttggggaaga cgacagggca tatcacatct
     5221 gcaaggatat agacctgata aaatacagcg tcttcccgga aggatttatg gtgagggctt
     5281 cctccatgga agcgcgggag caggtgcggg taggaaaaaa ggctgtgaag gatggactgt
     5341 cctttgcgca gataggaaat ctgtttatca ggaaatattt ggaatatccc aaagtgagag
     5401 ctgtgcaggt tcttttcata accggggaga ctgcagattt caaagggctt ggccggctgg
     5461 cagagaaaaa taaaatgata acaaaggcac tgaataaaat catggaaaag gcagacaagg
     5521 agtgcagcac ctgtggatta aaggaaatct gtgatgaggt ggaaggactt cggaagatgc
     5581 attttcagaa cagaaagagg tgacacgttt gaaaacagat aagatcgttc agaagctggt
     5641 agacagctac gggagctggg tgcaggagga aaaagaaaac tgtcccggtc attgtgctgt
     5701 catgagtaaa gagctttacc cctatgacgc aattttttca cctattcggg tcaaccgcat
     5761 cacactgaaa aacagggtgg tcatggcacc tatgggaaac ctgaacatgt gtgaggagaa
     5821 cgggcggccc agtgacaaga tgctccagta tttctttgcc agggcaaaag gcggcaccgg
     5881 tcttctcaca acaggactga tccccatcag ccacggtatt gacaatacag tgacagagcc
     5941 ggggaagttg agttttttcc cgaggatcga cagaagccgg actgtttttt cgggatggag
     6001 ggatctggca cagggtgtcc atgcgtacgg aagccgcatt ttcatccagc tcaccccggg
     6061 actcggaaga gtgggaccgc ctcagtgtgt catcaatgag atgaagctcc cctgttcggc
     6121 atccctgaat cccaactttt acattcccga gcttccctgt ctgccgctta cggatctggc
     6181 ccttcacaag atcataaaaa atggtggaca ggcggcatcc gacgcaaaga cggcaggcct
     6241 tgatggtgtc tatctgcacg ggcatgaggg atatctgctg gaccagctca cgaacccggc
     6301 cttcaacaga agaaaagcgg gaagatacgc ctactggcaa aactttggcc tggacttggt
     6361 acgggagatc agaaagcggg tgggggacag ctatcccatc atgtacagga tcgatctgtc
     6421 cctggctctc aatgagacct acaaagagcg gatggagagt gtgagatccc tgaagaaatt
     6481 tacaaacggc agaaccatct atgacaccct gcgctatatg gaaaacctgg taaaagcagg
     6541 cgtagatatg tttgatgtgg atctgggctg ctatgataac tggtggctgc ctcatccccc
     6601 ggcaggtatg ccggcaggct gcttcctgga tatttccagg atcgcaaaga aatatttcaa
     6661 gaccagggaa gtaaagacca atgccggtct ggaagtgcct gttgtggcgg tgggcaaact
     6721 gggatatccg gatttggcgg agaaggccat aagagacggt atgtgtgatc ttgtcatgct
     6781 gggccggccc cttctggctg acccggactg gtgcagaaag gcatatgccg gagaggtgga
     6841 gagaatccgt ccctgcatcg gatgccagga gggctgtatc aacgagtttg tggagggcgg
     6901 ccatcctcaa tgcgcagtga accccagaac cgggtttgag gatgtgatcc ccgagacact
     6961 gccgagagcg gagaacacaa agaagatcgc agttgtggga gctggtccct caggcatgca
     7021 gtttgccctg accgcttctg cccggggaca tcaggtgaca ctgatcgagc gggaaaaaat
     7081 actcggcggc aaggtggtac ccggcagcag accaaagatc aaatttgatt ttaagaatta
     7141 tctggagtac ctcataagag aggtacatct ggcagaggaa aaaggcggtc ttaccgtgtg
     7201 caccggtgta gaggcagaca cccaatggct gaaagagcaa aactttgatg ccattgtcta
     7261 caatatcgga accaccagtg tagtacccaa aatcccaggt gtggaccagg cagactgggt
     7321 acaggccaca gaccttctct gcgagccgga gaaactggga aaagcaaaga aaaccgtagt
     7381 catcggcggc ggcgttgtag gatgcgagac agcatactgg ctcaaatacg aaaaaggatg
     7441 cgacgtgaca gtggtggaga tgctgcccta cattatgagc ggcgcctgca cagccaaccg
     7501 ataccatttg atccactaca tggaaaaagc cggtgtacag cttctaaact gtgcaaaagt
     7561 gacaggcttt acaaaaggca gtgtccagat cgaaaaaaac atttcaaaag gcgtaccgga
     7621 cccctacaac acctggcagc cccaactgcc tgagaacata gccaaccccc tggccaaaaa
     7681 gatcggaccc gagacagaaa accaggaact tcccgccgat ctggtaatat tcgccatggg
     7741 cggaagaccg gatgaaagcc tatacctgga aggcctcaga ctacatgcag ccaaagaact
     7801 ctacaacatc ggcgacagct tctctggcgg aagagtactt gaagcatccc gcgctgcata
     7861 ccgtttggca agggaaattt aagcggtaat attttggcag gagggacggg atggcggggg
     7921 aggctggtgt cctcttatgg cagccagctt cgttcccctt caactaatca ctaacttcga
     7981 ctaagacgct cagtaaagac ttcgcgccaa gtctccgtaa gtgatggatt ttcaggctca
     8041 ctgacgcaat gtctgccata agaggacacc agcctccccc gccatccctg gtttttcctg
     8101 ccgaaaggtg atgaaagaac aagaaagcca gacagttgtg aacagccaaa tatcccacaa
     8161 actgtgacgc acagcttgcc aaaagtaatt tccagacatt ctgatatttg aaaaaatgtt
     8221 aaatattaaa aagacctgtg ggccaaagaa gaacaggaaa aggatggaag gggccggggc
     8281 ggggaaactg tgagcgatgt atagtggagc gcccggagat ccacctgccc cagttactta
     8341 atgaagaggc caatgccgat gaatttagta actgggagca ggttagctcc gtg
//
