## Fri May 2 14:37:06 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_020736685.1/GCA_020736685.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_020736685.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_020736685.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs OGLMJJLJ_00001 173707.Q938L8_9CAUD 4.27e-41 140.0 4QDP9@10239|Viruses,4QWR2@35237|dsDNA viruses no RNA stage,4QQY8@28883|Caudovirales,4QMYB@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - OGLMJJLJ_00004 1461246.X2KPG8_9VIRU 1.48e-30 114.0 4QAXV@10239|Viruses 10239|Viruses S YopX protein - - - - - - - - - - - - - OGLMJJLJ_00006 73422.L0P3M1_9CAUD 2.46e-33 122.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - OGLMJJLJ_00007 768726.HMPREF9178_1077 7.8e-39 137.0 2DKDX@1|root,3098Q@2|Bacteria,1U4MH@1239|Firmicutes,4I04V@91061|Bacilli,2TQ21@28037|Streptococcus mitis 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 OGLMJJLJ_00009 1123315.AUIP01000014_gene1938 1.69e-39 140.0 2DS9F@1|root,33F4A@2|Bacteria,1VMJG@1239|Firmicutes,4HSZ4@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 OGLMJJLJ_00012 1123309.AQYB01000014_gene918 1.5e-15 70.1 2BK0S@1|root,32EDT@2|Bacteria,1TZGK@1239|Firmicutes,4HSJ1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00014 112023.Q9MCM0_9CAUD 5.46e-102 295.0 4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - OGLMJJLJ_00015 646413.C5IUI2_9CAUD 2.22e-83 248.0 4QAU9@10239|Viruses,4QVR2@35237|dsDNA viruses no RNA stage,4QQV4@28883|Caudovirales,4QKUJ@10699|Siphoviridae 10699|Siphoviridae S Single-strand binding protein family - - - - - - - - - - - - - OGLMJJLJ_00016 1239381.K4JU67_9CAUD 2.47e-60 203.0 4QB3F@10239|Viruses,4QV3C@35237|dsDNA viruses no RNA stage,4QPZ0@28883|Caudovirales,4QM6P@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1351) - - - - - - - - - - - - - OGLMJJLJ_00017 35344.A0A097PBE8_BPT12 3.03e-40 144.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QNJQ@10744|Podoviridae 10744|Podoviridae S ERF superfamily - - - - - - - - - - - - - OGLMJJLJ_00019 633135.C9WB96_9CAUD 1.93e-171 480.0 4QBU2@10239|Viruses,4QV13@35237|dsDNA viruses no RNA stage,4QPH3@28883|Caudovirales,4QM65@10699|Siphoviridae 10699|Siphoviridae S IstB-like ATP binding protein - - - - - - - - - - - - - OGLMJJLJ_00020 1035184.HMPREF1042_1642 3.91e-110 326.0 COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,4HMRU@91061|Bacilli,42EBW@671232|Streptococcus anginosus group 91061|Bacilli L N-terminal phage replisome organiser (Phage_rep_org_N) - - - - - - - - - - - - DnaB_2,Phage_rep_org_N,Phg_2220_C OGLMJJLJ_00024 1069533.Sinf_0769 1.99e-34 120.0 2ENNN@1|root,33GA0@2|Bacteria,1VN2K@1239|Firmicutes,4HR9I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00026 646413.C5IUM1_9CAUD 2.69e-176 496.0 4QAPQ@10239|Viruses,4QZ6P@35237|dsDNA viruses no RNA stage,4QPWV@28883|Caudovirales,4QMUB@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - OGLMJJLJ_00027 64186.O21995_9CAUD 1.54e-38 129.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010944,GO:0016032,GO:0019012,GO:0019042,GO:0019044,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043900,GO:0043902,GO:0043903,GO:0044212,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0046782,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0050434,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - OGLMJJLJ_00028 64186.O21993_9CAUD 1.58e-68 208.0 4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010944,GO:0016032,GO:0019012,GO:0019042,GO:0019044,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043900,GO:0043902,GO:0043903,GO:0044212,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0046782,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0050434,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - OGLMJJLJ_00029 173707.Q938N7_9CAUD 2.44e-19 84.3 4QFPY@10239|Viruses,4QX5A@35237|dsDNA viruses no RNA stage,4QPUR@28883|Caudovirales,4QKSN@10699|Siphoviridae 10699|Siphoviridae S Pfam:Peptidase_M78 - - - - - - - - - - - - - OGLMJJLJ_00030 1385385.U6E9C7_9CAUD 1.93e-49 162.0 4QBN1@10239|Viruses,4QZ19@35237|dsDNA viruses no RNA stage,4QQWW@28883|Caudovirales,4QKN7@10699|Siphoviridae 10699|Siphoviridae S Host cell surface-exposed lipoprotein - - - - - - - - - - - - - OGLMJJLJ_00031 646413.C5IUL7_9CAUD 4.9e-266 730.0 4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses no RNA stage,4QPDM@28883|Caudovirales,4QKN9@10699|Siphoviridae 10699|Siphoviridae S Phage integrase family - GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - - - - - - - - - - - OGLMJJLJ_00032 1046629.Ssal_01521 4.14e-313 853.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N OGLMJJLJ_00033 264199.stu0634 6.96e-100 290.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 OGLMJJLJ_00034 322159.STER_0682 2.96e-265 726.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes 1239|Firmicutes G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase OGLMJJLJ_00035 322159.STER_0681 5.96e-59 185.0 COG2315@1|root,COG2315@2|Bacteria 2|Bacteria V Protein conserved in bacteria yyaQ - - - - - - - - - - - YjbR OGLMJJLJ_00036 904306.HMPREF9192_1362 8.52e-34 124.0 COG2315@1|root,COG2315@2|Bacteria,1V4K7@1239|Firmicutes,4HP2K@91061|Bacilli 91061|Bacilli S YjbR XK27_07735 - - - - - - - - - - - EVE,YjbR OGLMJJLJ_00037 322159.STER_0679 2.71e-235 647.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli 91061|Bacilli K Catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 OGLMJJLJ_00038 264199.stu0629 3.33e-266 728.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli 91061|Bacilli E Belongs to the peptidase M24B family pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 OGLMJJLJ_00039 264199.stu0628 1.08e-84 249.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli 91061|Bacilli J RNA binding protein, contains ribosomal protein S1 domain yugI - - ko:K07570 - - - - ko00000 - - - S1 OGLMJJLJ_00040 322159.STER_0676 0.0 949.0 COG0561@1|root,COG0652@1|root,COG0561@2|Bacteria,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase OGLMJJLJ_00041 264199.stu0626 5.69e-105 303.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli 91061|Bacilli O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB OGLMJJLJ_00042 264199.stu0625 0.0 1568.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 OGLMJJLJ_00043 322159.STER_0673 1.5e-44 144.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli 91061|Bacilli U Preprotein translocase subunit SecG secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG OGLMJJLJ_00044 264199.stu0622 2.41e-280 768.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli 91061|Bacilli EGP Major Facilitator pmrA - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr OGLMJJLJ_00045 264199.stu0621 2.68e-137 389.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli 91061|Bacilli H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE OGLMJJLJ_00046 264199.stu0620 1.92e-198 549.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS OGLMJJLJ_00047 264199.stu0619 1.16e-212 587.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli 91061|Bacilli M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 OGLMJJLJ_00048 264199.stu0618 9.96e-85 250.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar OGLMJJLJ_00049 264199.stu0617 8.88e-112 321.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 OGLMJJLJ_00050 904306.HMPREF9192_1347 3.45e-82 249.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli 91061|Bacilli K antiterminator licT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD OGLMJJLJ_00051 264199.stu0615 1.74e-57 181.0 COG3711@1|root,COG3711@2|Bacteria 2|Bacteria K transcriptional antiterminator licT - - ko:K02538,ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD OGLMJJLJ_00052 264199.stu0614 1.85e-136 386.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 OGLMJJLJ_00053 264199.stu0613 0.0 1293.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase OGLMJJLJ_00054 322159.STER_0661 1.18e-190 530.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N OGLMJJLJ_00055 322159.STER_0660 5.95e-203 561.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C OGLMJJLJ_00056 1046629.Ssal_01547 4.53e-30 112.0 COG2267@1|root,COG2267@2|Bacteria,1V37Y@1239|Firmicutes,4ITDD@91061|Bacilli 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 OGLMJJLJ_00057 264199.stu0609 1.61e-44 144.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity yugF GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1 OGLMJJLJ_00058 663952.SDD27957_07575 9.87e-12 59.7 2DJ8A@1|root,304YV@2|Bacteria,1TXF8@1239|Firmicutes,4I6DK@91061|Bacilli,1MA5P@119603|Streptococcus dysgalactiae group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00059 264199.stu0608 0.0 1352.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate OGLMJJLJ_00060 264199.stu0607 2.47e-101 294.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4HPFS@91061|Bacilli 91061|Bacilli P FeoA domain protein feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA OGLMJJLJ_00061 264199.stu0606 4.45e-169 473.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran OGLMJJLJ_00062 264199.stu0605 3.24e-151 426.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4IQKK@91061|Bacilli 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 OGLMJJLJ_00063 264199.stu0604 1.15e-47 152.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli 91061|Bacilli S protein conserved in bacteria ykuJ - - - - - - - - - - - DUF1797 OGLMJJLJ_00064 264199.stu0603 1.1e-231 639.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N OGLMJJLJ_00065 264199.stu0602 0.0 1417.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR OGLMJJLJ_00066 322159.STER_0647 3.73e-109 313.0 COG0494@1|root,COG0494@2|Bacteria,1VH6Q@1239|Firmicutes,4HQVJ@91061|Bacilli 91061|Bacilli L Belongs to the Nudix hydrolase family XK27_09440 - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX OGLMJJLJ_00067 1046629.Ssal_01559 7.49e-64 195.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 OGLMJJLJ_00068 264199.stu0599 2.68e-11 59.3 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity ydgJ - 1.1.1.371 ko:K16044 ko00562,ko01120,map00562,map01120 - R09954 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C OGLMJJLJ_00069 435842.HMPREF0848_00232 5.16e-52 172.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HDXF@91061|Bacilli 91061|Bacilli S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C OGLMJJLJ_00070 435842.HMPREF0848_00232 2.22e-65 207.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HDXF@91061|Bacilli 91061|Bacilli S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C OGLMJJLJ_00071 322159.STER_0644 5.43e-295 805.0 COG2348@1|root,COG2348@2|Bacteria,1V181@1239|Firmicutes,4HEVU@91061|Bacilli 91061|Bacilli V FemAB family murN - - ko:K12554 ko00550,ko01100,map00550,map01100 - R08780 RC00055,RC00064 ko00000,ko00001,ko01000,ko01011 - - - FemAB OGLMJJLJ_00072 1046629.Ssal_01562 2.42e-81 246.0 COG0398@1|root,COG0398@2|Bacteria 2|Bacteria M Pfam SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc OGLMJJLJ_00073 904306.HMPREF9192_1327 6.33e-132 375.0 2DMIQ@1|root,32RV1@2|Bacteria,1VGN9@1239|Firmicutes,4I0DZ@91061|Bacilli 91061|Bacilli S Domain of Unknown Function with PDB structure (DUF3862) - - - - - - - - - - - - DUF3862 OGLMJJLJ_00076 264199.stu0592 7.94e-266 731.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli 91061|Bacilli J ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 OGLMJJLJ_00079 1035187.HMPREF9959_0525 1.4e-21 86.7 29N96@1|root,30971@2|Bacteria,1U4J6@1239|Firmicutes,4IEAX@91061|Bacilli,2TPZ6@28037|Streptococcus mitis 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 OGLMJJLJ_00080 264199.stu0590 8.31e-254 695.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli 91061|Bacilli E Aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 OGLMJJLJ_00081 264199.stu0589 0.0 1558.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV OGLMJJLJ_00082 322159.STER_0633 0.0 1252.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim OGLMJJLJ_00083 322159.STER_0632 4.27e-138 392.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf OGLMJJLJ_00084 759913.SDSE_1678 2.2e-20 87.0 2DJ7H@1|root,304X7@2|Bacteria,1TXCP@1239|Firmicutes,4I6AH@91061|Bacilli,1M9TG@119603|Streptococcus dysgalactiae group 91061|Bacilli L Helix-hairpin-helix DNA-binding motif class 1 - - - - - - - - - - - - HHH_5 OGLMJJLJ_00085 1035184.HMPREF1042_0385 5.22e-41 136.0 2BXCI@1|root,346RD@2|Bacteria,1VYRT@1239|Firmicutes,4HYPP@91061|Bacilli,42DR8@671232|Streptococcus anginosus group 91061|Bacilli S Domain of unknown function (DUF1912) - - - - - - - - - - - - DUF1912 OGLMJJLJ_00086 264199.stu0584 4.42e-227 625.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli 91061|Bacilli H Homocysteine mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans OGLMJJLJ_00087 264199.stu0583 5.16e-316 863.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes,4HUT7@91061|Bacilli 91061|Bacilli E amino acid ybgF - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - - AA_permease OGLMJJLJ_00088 264199.stu0582 6.75e-144 405.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 OGLMJJLJ_00089 322159.STER_0625 4.22e-286 782.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX OGLMJJLJ_00090 435842.HMPREF0848_00215 2.97e-30 107.0 2DFKW@1|root,2ZS8U@2|Bacteria,1W5G0@1239|Firmicutes,4HZFD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00091 322159.STER_0623 7.3e-121 344.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 OGLMJJLJ_00092 322159.STER_0622 2.98e-213 588.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4HI1C@91061|Bacilli 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt OGLMJJLJ_00093 264199.stu0577 1.28e-278 762.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli 91061|Bacilli I synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N OGLMJJLJ_00094 322159.STER_0620 1.76e-297 812.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red OGLMJJLJ_00095 904306.HMPREF9192_1305 3.81e-35 122.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes 1239|Firmicutes K hmm pf08876 - - - - - - - - - - - - DUF1836 OGLMJJLJ_00096 322159.STER_0618 1.01e-151 427.0 COG1272@1|root,COG1272@2|Bacteria,1TTA5@1239|Firmicutes,4HDYT@91061|Bacilli 91061|Bacilli K protein, Hemolysin III hly-III - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII OGLMJJLJ_00097 904306.HMPREF9192_1302 6.8e-28 108.0 2DQ82@1|root,3357U@2|Bacteria,1VFZ3@1239|Firmicutes,4HNXV@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3114) - - - - - - - - - - - - DUF3114 OGLMJJLJ_00098 264199.stu0574 1.93e-210 581.0 2DQ82@1|root,3357U@2|Bacteria,1VFZ3@1239|Firmicutes,4HNXV@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3114) - - - - - - - - - - - - DUF3114 OGLMJJLJ_00099 264199.stu0573 1.83e-90 271.0 COG0596@1|root,COG0596@2|Bacteria,1V202@1239|Firmicutes,4HJ0U@91061|Bacilli 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 OGLMJJLJ_00100 264199.stu0573 2.71e-60 194.0 COG0596@1|root,COG0596@2|Bacteria,1V202@1239|Firmicutes,4HJ0U@91061|Bacilli 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 OGLMJJLJ_00101 264199.stu0572 0.0 1309.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD OGLMJJLJ_00102 889204.HMPREF9423_1244 3.19e-66 201.0 2DMJF@1|root,32RYX@2|Bacteria,1VBNS@1239|Firmicutes,4HMXU@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00103 264199.stu0570 0.0 864.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 OGLMJJLJ_00104 322159.STER_0610 8.17e-242 664.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HBKA@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein dgs - 2.4.1.208 ko:K13677 ko00561,ko01100,map00561,map01100 - R05164 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 OGLMJJLJ_00105 1046629.Ssal_01596 9.13e-14 75.5 COG3156@1|root,COG4932@1|root,COG3156@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,MucBP,SdrD_B,T2SSK,YSIRK_signal OGLMJJLJ_00106 1046629.Ssal_01596 3.8e-58 202.0 COG3156@1|root,COG4932@1|root,COG3156@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,MucBP,SdrD_B,T2SSK,YSIRK_signal OGLMJJLJ_00107 1046629.Ssal_01596 3.42e-35 134.0 COG3156@1|root,COG4932@1|root,COG3156@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,MucBP,SdrD_B,T2SSK,YSIRK_signal OGLMJJLJ_00109 264199.stu0566 7.33e-152 428.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 OGLMJJLJ_00110 322159.STER_0605 1.47e-41 137.0 2DC3Q@1|root,2ZCSA@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - OGLMJJLJ_00111 322159.STER_0604 8.64e-125 355.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli 91061|Bacilli L AdP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX OGLMJJLJ_00112 322159.STER_0603 0.0 880.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase OGLMJJLJ_00113 1046629.Ssal_01605 4.16e-235 647.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh OGLMJJLJ_00114 322159.STER_0600 3.24e-226 624.0 COG1577@1|root,COG1577@2|Bacteria,1VXNZ@1239|Firmicutes,4IRFS@91061|Bacilli 91061|Bacilli I GHMP kinases N terminal domain mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N OGLMJJLJ_00115 264199.stu0560 8.91e-220 607.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N OGLMJJLJ_00116 264199.stu0559 1.93e-187 523.0 COG1577@1|root,COG1577@2|Bacteria,1TPVW@1239|Firmicutes,4IRCB@91061|Bacilli 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N OGLMJJLJ_00117 264199.stu0558 1.33e-135 383.0 COG3575@1|root,COG3575@2|Bacteria,1V1YD@1239|Firmicutes,4HGK6@91061|Bacilli 91061|Bacilli J protein conserved in bacteria - - - ko:K09962 - - - - ko00000 - - - NTP_transf_6 OGLMJJLJ_00118 264199.stu0557 1.69e-314 857.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim OGLMJJLJ_00119 435842.HMPREF0848_00185 4.82e-59 192.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli 91061|Bacilli C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N OGLMJJLJ_00120 264199.stu0555 1.29e-24 92.0 COG0686@1|root,COG0686@2|Bacteria 2|Bacteria E alanine dehydrogenase activity ald GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - iAF987.Gmet_1099 AlaDh_PNT_C,AlaDh_PNT_N OGLMJJLJ_00121 322159.STER_0594 5.03e-278 759.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase hipO2 - - ko:K01436,ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 OGLMJJLJ_00122 322159.STER_0593 3.15e-171 478.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 OGLMJJLJ_00123 322159.STER_0592 6.25e-147 415.0 COG1814@1|root,COG1814@2|Bacteria,1V6KW@1239|Firmicutes,4IPIC@91061|Bacilli 91061|Bacilli S VIT family - - - - - - - - - - - - VIT1 OGLMJJLJ_00124 322159.STER_0591 4.31e-182 506.0 COG2820@1|root,COG2820@2|Bacteria,1V6T2@1239|Firmicutes,4HCSE@91061|Bacilli 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 OGLMJJLJ_00126 1046629.Ssal_01621 5.22e-37 124.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli 91061|Bacilli K Transcriptional XK27_00085 - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 OGLMJJLJ_00127 1046629.Ssal_01622 1.13e-249 683.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli 91061|Bacilli S Belongs to the UPF0176 family ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C OGLMJJLJ_00128 264199.stu0547 1.79e-157 443.0 COG1511@1|root,COG1511@2|Bacteria,1USMY@1239|Firmicutes,4HC3J@91061|Bacilli 91061|Bacilli S ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane OGLMJJLJ_00129 322159.STER_0586 8.21e-215 593.0 COG1131@1|root,COG1131@2|Bacteria,1UZK5@1239|Firmicutes,4HB2Q@91061|Bacilli 91061|Bacilli V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran OGLMJJLJ_00130 264199.stu0545 1.18e-227 630.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli 91061|Bacilli H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 thiF - 2.7.7.73 ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF OGLMJJLJ_00131 264199.stu0545 9.22e-34 125.0 COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli 91061|Bacilli H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 thiF - 2.7.7.73 ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF OGLMJJLJ_00132 322159.STER_0583 4.85e-169 472.0 COG3279@1|root,COG3279@2|Bacteria,1TXDF@1239|Firmicutes,4HDA7@91061|Bacilli 91061|Bacilli KT response regulator rr02 - - - - - - - - - - - LytTR,Response_reg OGLMJJLJ_00133 322159.STER_0582 8.65e-293 801.0 COG3290@1|root,COG3290@2|Bacteria,1UDI2@1239|Firmicutes,4HF65@91061|Bacilli 91061|Bacilli T signal transduction protein with a C-terminal ATPase domain hk02 - - - - - - - - - - - HATPase_c_5 OGLMJJLJ_00134 1046629.Ssal_01624 7.37e-158 443.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso OGLMJJLJ_00135 322159.STER_0580 4.12e-253 694.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth OGLMJJLJ_00136 322159.STER_0579 0.0 1132.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA - - ko:K06147,ko:K18888 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_00137 322159.STER_0578 0.0 1097.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein msbA_1 - - ko:K18887 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_membrane,ABC_tran OGLMJJLJ_00139 322159.STER_0576 0.0 1363.0 COG3266@1|root,COG3266@2|Bacteria,1V15F@1239|Firmicutes 1239|Firmicutes M the current gene model (or a revised gene model) may contain a - - - - - - - - - - - - Gram_pos_anchor,MucBP,YSIRK_signal OGLMJJLJ_00140 904306.HMPREF9192_0446 2.21e-59 204.0 COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1UYRE@1239|Firmicutes,4ISZF@91061|Bacilli 91061|Bacilli M YSIRK type signal peptide - - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal OGLMJJLJ_00141 322159.STER_0574 1.16e-127 371.0 2DVN5@1|root,33WG3@2|Bacteria 2|Bacteria S MucBP domain - - - - - - - - - - - - MucBP OGLMJJLJ_00144 322159.STER_1347 1.21e-225 624.0 COG0577@1|root,COG0577@2|Bacteria,1VRMK@1239|Firmicutes,4HTA7@91061|Bacilli 2|Bacteria V MacB-like periplasmic core domain hrtB - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD OGLMJJLJ_00145 322159.STER_1348 1.62e-152 429.0 COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,4HBXK@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran OGLMJJLJ_00146 1410626.JHXB01000031_gene1709 1.25e-23 96.7 COG2801@1|root,COG2801@2|Bacteria,1TRUP@1239|Firmicutes,24AJD@186801|Clostridia,27KEC@186928|unclassified Lachnospiraceae 186801|Clostridia L Integrase core domain - - - - - - - - - - - - HTH_21,rve,rve_3 OGLMJJLJ_00147 1116231.SMA_0720 1.47e-293 803.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4HJK9@91061|Bacilli 91061|Bacilli L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00148 1116231.SMA_1153 2.51e-304 828.0 COG0582@1|root,COG0582@2|Bacteria,1VRXQ@1239|Firmicutes,4HUID@91061|Bacilli 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase OGLMJJLJ_00149 1214166.ALLG01000022_gene225 1.02e-38 130.0 29R26@1|root,30C3A@2|Bacteria,1U93V@1239|Firmicutes,4IJ4N@91061|Bacilli,1WTPP@1307|Streptococcus suis 91061|Bacilli S Domain of unknown function (DUF3173) - - - - - - - - - - - - DUF3173 OGLMJJLJ_00150 1116231.SMA_1373 5.4e-43 140.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli 91061|Bacilli K transcriptional xre - - - - - - - - - - - HTH_19,HTH_3 OGLMJJLJ_00151 866775.HMPREF9243_1999 2.24e-90 273.0 COG4200@1|root,COG4200@2|Bacteria,1V3PM@1239|Firmicutes,4HHIJ@91061|Bacilli 91061|Bacilli S ABC-2 family transporter protein - - - ko:K20461 ko02010,map02010 M00813 - - ko00000,ko00001,ko00002,ko02000 3.A.1.124.3,3.A.1.124.4,3.A.1.124.5 - - ABC2_membrane_4 OGLMJJLJ_00152 764298.STRMA_1787 1.57e-105 312.0 COG4200@1|root,COG4200@2|Bacteria,1V5VS@1239|Firmicutes,4HH7H@91061|Bacilli 91061|Bacilli S ABC-2 family transporter protein - - - ko:K20460 ko02010,map02010 M00813 - - ko00000,ko00001,ko00002,ko02000 3.A.1.124.3,3.A.1.124.4,3.A.1.124.5 - - ABC2_membrane_4 OGLMJJLJ_00153 764298.STRMA_1786 6.51e-147 421.0 COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,4HBGH@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein bcrA - - ko:K20459 ko02010,map02010 M00813 - - ko00000,ko00001,ko00002,ko02000 3.A.1.124.3,3.A.1.124.4,3.A.1.124.5 - - ABC_tran OGLMJJLJ_00154 40041.SZO_07670 6.33e-273 772.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,1M9ZS@119603|Streptococcus dysgalactiae group 91061|Bacilli V Lantibiotic transport processing ATP-binding protein - - - ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_00156 764298.STRMA_1785 1.5e-126 364.0 COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,4HBUE@91061|Bacilli 91061|Bacilli T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - - - - - - - - - - Response_reg,Trans_reg_C OGLMJJLJ_00157 764298.STRMA_1784 1.57e-212 600.0 COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,4HEKK@91061|Bacilli 91061|Bacilli T Histidine kinase scnK - - - - - - - - - - - HATPase_c,HisKA OGLMJJLJ_00158 1116231.SMA_1385 2.56e-279 776.0 COG3843@1|root,COG3843@2|Bacteria,1V2SB@1239|Firmicutes,4HFEX@91061|Bacilli 91061|Bacilli U relaxase - - - - - - - - - - - - Relaxase,Streptin-Immun OGLMJJLJ_00159 904306.HMPREF9192_1426 1.15e-89 279.0 COG3843@1|root,COG3843@2|Bacteria,1V2SB@1239|Firmicutes,4HFEX@91061|Bacilli 91061|Bacilli U relaxase - - - - - - - - - - - - Relaxase,Streptin-Immun OGLMJJLJ_00160 246201.SM12261_0096 6.28e-75 224.0 2DKBU@1|root,3094K@2|Bacteria,1U4EX@1239|Firmicutes,4IE7E@91061|Bacilli,2TPSS@28037|Streptococcus mitis 91061|Bacilli S Bacterial mobilisation protein (MobC) - - - - - - - - - - - - MobC OGLMJJLJ_00161 904306.HMPREF9192_1424 1.49e-72 218.0 2BWBR@1|root,2ZDFR@2|Bacteria,1W52Y@1239|Firmicutes,4I0XT@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00162 1116231.SMA_1416 3.35e-43 151.0 2E2ST@1|root,32XV1@2|Bacteria,1VDTP@1239|Firmicutes,4HYGP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00163 1116231.SMA_1417 2.25e-116 338.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii OGLMJJLJ_00164 1116231.SMA_1418 9.22e-141 397.0 COG5340@1|root,COG5340@2|Bacteria,1V3JU@1239|Firmicutes,4HMVW@91061|Bacilli 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin - - - - - - - - - - - - AbiEi_4 OGLMJJLJ_00165 663952.SDD27957_04360 0.0 1263.0 COG3942@1|root,COG3942@2|Bacteria,1VPFZ@1239|Firmicutes,4HFGV@91061|Bacilli 91061|Bacilli M CHAP domain protein XK27_00530 - - - - - - - - - - - CHAP,Peptidase_M23 OGLMJJLJ_00166 663952.SDD27957_04360 1.72e-51 183.0 COG3942@1|root,COG3942@2|Bacteria,1VPFZ@1239|Firmicutes,4HFGV@91061|Bacilli 91061|Bacilli M CHAP domain protein XK27_00530 - - - - - - - - - - - CHAP,Peptidase_M23 OGLMJJLJ_00167 873448.STRPO_2031 0.0 1499.0 COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,4HUB9@91061|Bacilli 91061|Bacilli U 'COG3451 Type IV secretory pathway, VirB4 components' - - - - - - - - - - - - AAA_10,DUF87 OGLMJJLJ_00168 996306.SSUR61_1148 4.32e-71 214.0 2AMBF@1|root,31C6I@2|Bacteria,1U92M@1239|Firmicutes,4IJ34@91061|Bacilli,1WTK7@1307|Streptococcus suis 91061|Bacilli S PrgI family protein XK27_00550 - - - - - - - - - - - PrgI OGLMJJLJ_00169 1123304.AQYA01000037_gene305 1.19e-177 498.0 2EFFF@1|root,33986@2|Bacteria,1VY42@1239|Firmicutes,4HMPN@91061|Bacilli 91061|Bacilli - - XK27_00555 - - - - - - - - - - - TrbL OGLMJJLJ_00170 1116231.SMA_1423 1.04e-45 147.0 295KB@1|root,2ZSXU@2|Bacteria,1W4XR@1239|Firmicutes,4I17I@91061|Bacilli 91061|Bacilli - - XK27_00560 - - - - - - - - - - - - OGLMJJLJ_00171 1116231.SMA_1424 0.0 1207.0 COG3505@1|root,COG3505@2|Bacteria,1UAJF@1239|Firmicutes,4IPX4@91061|Bacilli 91061|Bacilli U COG3505 Type IV secretory pathway, VirD4 components XK27_00565 - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf OGLMJJLJ_00172 663952.SDD27957_08365 6.91e-55 174.0 29R8I@1|root,30C9Y@2|Bacteria,1U9FT@1239|Firmicutes,4IJJE@91061|Bacilli,1MA0F@119603|Streptococcus dysgalactiae group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00173 1123304.AQYA01000037_gene301 9.73e-116 333.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - 3.4.11.19 ko:K01266,ko:K07052 - - - - ko00000,ko01000,ko01002 - - - Abi OGLMJJLJ_00174 663952.SDD27957_04310 4.47e-50 158.0 2DJ81@1|root,304Y6@2|Bacteria,1TXEG@1239|Firmicutes,4I6CS@91061|Bacilli,1MA3U@119603|Streptococcus dysgalactiae group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00175 1403946.Q615_SPAC00123G0036 1.1e-65 202.0 2DIU1@1|root,3044F@2|Bacteria,1TW0J@1239|Firmicutes,4I4P9@91061|Bacilli,42EHG@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00176 883168.HMPREF9318_00463 1.33e-95 278.0 2EV5A@1|root,33NK4@2|Bacteria,1W4PT@1239|Firmicutes 1239|Firmicutes - - XK27_00590 - - - - - - - - - - - - OGLMJJLJ_00177 1123304.AQYA01000037_gene298 0.0 898.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HB9C@91061|Bacilli 91061|Bacilli H cytosine-specific methyltransferase hpaIIM - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase OGLMJJLJ_00178 663952.SDD27957_04290 7.89e-16 68.9 2DJ8F@1|root,304Z3@2|Bacteria,1TXFK@1239|Firmicutes,4I6DZ@91061|Bacilli,1MA66@119603|Streptococcus dysgalactiae group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00179 759913.SDSE_1324 2.99e-182 508.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,1M9YD@119603|Streptococcus dysgalactiae group 91061|Bacilli S Replication initiator protein A (RepA) N-terminus repA - - - - - - - - - - - RepA_N OGLMJJLJ_00180 759913.SDSE_1325 3.59e-27 99.4 2BMA2@1|root,32FTX@2|Bacteria,1TXF4@1239|Firmicutes,4I6DG@91061|Bacilli,1MA5I@119603|Streptococcus dysgalactiae group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00181 322159.STER_0568 7.29e-70 212.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N OGLMJJLJ_00182 435842.HMPREF0848_00164 4e-100 292.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 OGLMJJLJ_00183 264199.stu0535 4.02e-38 127.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity ytrF - - ko:K02004,ko:K16918 ko02010,map02010 M00258,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD OGLMJJLJ_00184 264199.stu0533 1.07e-44 147.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD OGLMJJLJ_00185 264199.stu0532 1.1e-46 150.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity - - - - - - - - - - - - MacB_PCD OGLMJJLJ_00186 322159.STER_0561 3.35e-168 471.0 COG4123@1|root,COG4123@2|Bacteria,1UJ4P@1239|Firmicutes,4IT17@91061|Bacilli 91061|Bacilli S Putative SAM-dependent methyltransferase - - - - - - - - - - - - SAM_MT OGLMJJLJ_00187 264199.stu0527 0.0 2055.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli 91061|Bacilli F carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS OGLMJJLJ_00188 322159.STER_0558 1.31e-268 734.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli 91061|Bacilli F carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase OGLMJJLJ_00189 264199.stu0525 8.28e-222 611.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N OGLMJJLJ_00190 322159.STER_0556 2.02e-288 790.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli 91061|Bacilli F uracil Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease OGLMJJLJ_00191 264199.stu0523 2.72e-114 329.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran OGLMJJLJ_00192 264199.stu0522 2.84e-207 573.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 OGLMJJLJ_00193 264199.stu0521 4.01e-100 291.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 OGLMJJLJ_00194 904306.HMPREF9192_0429 4.06e-214 591.0 COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli 91061|Bacilli K transcriptional regulator (lysR family) lysR - - - - - - - - - - - HTH_1,LysR_substrate OGLMJJLJ_00199 322159.STER_0545 1.5e-180 502.0 COG0652@1|root,COG0652@2|Bacteria 2|Bacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase OGLMJJLJ_00200 904306.HMPREF9192_0423 5.1e-228 644.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC OGLMJJLJ_00201 1046629.Ssal_01653 4.1e-30 117.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC OGLMJJLJ_00203 264199.stu0509 0.0 870.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli 91061|Bacilli E permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease OGLMJJLJ_00204 322159.STER_0151 2.53e-137 397.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00205 1046629.Ssal_01370 1.61e-26 105.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00207 264199.stu0508 1.42e-52 165.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 OGLMJJLJ_00208 322159.STER_0540 0.0 1277.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f OGLMJJLJ_00209 264199.stu0505 2.48e-226 622.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e OGLMJJLJ_00210 904306.HMPREF9192_0417 2.41e-79 247.0 COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,4HBYW@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - - OGLMJJLJ_00211 264199.stu0504 1.54e-80 239.0 COG3949@1|root,COG3949@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - OGLMJJLJ_00212 264199.stu0503 1.94e-34 119.0 COG3949@1|root,COG3949@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - OGLMJJLJ_00213 264199.stu0502 1.99e-69 209.0 COG3949@1|root,COG3949@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - OGLMJJLJ_00214 322159.STER_0537 1.98e-280 766.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 OGLMJJLJ_00215 1046629.Ssal_01661 4.96e-116 347.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU OGLMJJLJ_00216 322159.STER_0534 3.41e-192 533.0 COG0561@1|root,COG0561@2|Bacteria,1VAFW@1239|Firmicutes,4HIFQ@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase XK27_04800 - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_00217 264199.stu0496 3.1e-138 392.0 COG1705@1|root,COG1705@2|Bacteria,1UYRM@1239|Firmicutes 1239|Firmicutes NU mannosyl-glycoprotein mur1 - - ko:K02395,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM OGLMJJLJ_00218 322159.STER_0532 7.6e-70 211.0 COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes 1239|Firmicutes K Belongs to the P(II) protein family glnB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II OGLMJJLJ_00219 322159.STER_0531 1.14e-296 809.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli 91061|Bacilli P Ammonium Transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp OGLMJJLJ_00220 322159.STER_0151 3.06e-300 819.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00221 264199.stu0493 7.25e-206 569.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase OGLMJJLJ_00222 264199.stu0492 2.84e-73 219.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB OGLMJJLJ_00223 904306.HMPREF9192_0407 2.45e-178 498.0 COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli 91061|Bacilli S stage 0 sporulation protein yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 OGLMJJLJ_00224 904306.HMPREF9192_0406 4.86e-201 557.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli 91061|Bacilli L dna polymerase iii holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C OGLMJJLJ_00225 264199.stu0489 5.91e-143 404.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin OGLMJJLJ_00226 264199.stu0488 4.44e-173 483.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM OGLMJJLJ_00227 264199.stu0487 1.59e-285 780.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 OGLMJJLJ_00228 264199.stu0486 1.94e-290 795.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE OGLMJJLJ_00229 322159.STER_0522 6e-77 231.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N OGLMJJLJ_00230 322159.STER_0521 0.0 910.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N OGLMJJLJ_00231 264199.stu0483 4.5e-202 560.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt OGLMJJLJ_00232 264199.stu0482 0.0 959.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N OGLMJJLJ_00233 264199.stu0481 4.27e-114 328.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKW1@91061|Bacilli 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP OGLMJJLJ_00234 264199.stu0480 3.44e-100 292.0 COG0711@1|root,COG0711@2|Bacteria,1V74A@1239|Firmicutes 1239|Firmicutes C ATP synthase F(0) sector subunit b atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B OGLMJJLJ_00235 322159.STER_0516 1.81e-159 447.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A OGLMJJLJ_00236 1123298.KB904069_gene1213 2.91e-23 90.1 COG0636@1|root,2ZI0B@2|Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C OGLMJJLJ_00237 322159.STER_0513 0.0 1761.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 OGLMJJLJ_00238 322159.STER_0512 7.59e-90 263.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - 2.3.1.128,5.2.1.8 ko:K03768,ko:K03790 - - - - ko00000,ko01000,ko03009,ko03110 - - - Acetyltransf_3 OGLMJJLJ_00239 322159.STER_0511 2.01e-134 383.0 COG1853@1|root,COG1853@2|Bacteria,1VENC@1239|Firmicutes,4HQ31@91061|Bacilli 91061|Bacilli S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - - - - - - - - - - Flavin_Reduct OGLMJJLJ_00240 1123314.AUIO01000005_gene141 2.62e-17 81.3 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA OGLMJJLJ_00242 322159.STER_0508 5.16e-193 537.0 COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli 91061|Bacilli S Transporter rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA OGLMJJLJ_00243 1046629.Ssal_01693 3.96e-193 537.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli 91061|Bacilli E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06620 GHMP_kinases_C,GHMP_kinases_N OGLMJJLJ_00244 264199.stu0469 1.47e-303 828.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 OGLMJJLJ_00245 322159.STER_0504 1.11e-187 523.0 COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,4HHC9@91061|Bacilli 91061|Bacilli G deacetylase icaB - - - - - - - - - - - Polysacc_deac_1 OGLMJJLJ_00246 322159.STER_0503 2.64e-266 729.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli 91061|Bacilli E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 OGLMJJLJ_00247 264199.stu0466 4.42e-165 462.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes 1239|Firmicutes E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase OGLMJJLJ_00248 322159.STER_0501 4.21e-285 779.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ OGLMJJLJ_00249 264199.stu0464 1.12e-242 667.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC OGLMJJLJ_00250 322159.STER_0499 1.17e-289 790.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli 91061|Bacilli E mutations do not affect methionine salvage in vivo however mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 OGLMJJLJ_00251 264199.stu0462 1.29e-186 518.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase OGLMJJLJ_00252 264199.stu0461 3.78e-38 135.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity - - 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 - - - Amidase_3,CW_binding_1,GBS_Bsp-like,Glucosaminidase,Rod-binding,SH3_5,VanY,YSIRK_signal OGLMJJLJ_00253 264199.stu0461 9.04e-71 224.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity - - 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 - - - Amidase_3,CW_binding_1,GBS_Bsp-like,Glucosaminidase,Rod-binding,SH3_5,VanY,YSIRK_signal OGLMJJLJ_00254 322159.STER_0495 4.52e-185 521.0 COG0860@1|root,COG3942@1|root,COG0860@2|Bacteria,COG3942@2|Bacteria,1W25V@1239|Firmicutes,4HGXW@91061|Bacilli 91061|Bacilli M GBS Bsp-like repeat - - - - - - - - - - - - GBS_Bsp-like,Peptidase_C70,SH3_5,YSIRK_signal OGLMJJLJ_00255 264199.stu0457 0.0 1708.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD OGLMJJLJ_00256 862969.SCI_0200 1.27e-205 582.0 2AQ9M@1|root,31FFI@2|Bacteria,1V8H0@1239|Firmicutes,4ISNC@91061|Bacilli,42EJB@671232|Streptococcus anginosus group 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 OGLMJJLJ_00257 1302863.I872_03975 5.37e-161 456.0 COG3177@1|root,COG3177@2|Bacteria,1UIB2@1239|Firmicutes 1239|Firmicutes S Fic/DOC family - - - - - - - - - - - - Fic OGLMJJLJ_00259 862970.SAIN_0380 2.35e-147 419.0 COG1192@1|root,COG1192@2|Bacteria,1V6Q6@1239|Firmicutes,4HINH@91061|Bacilli 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 OGLMJJLJ_00261 1035184.HMPREF1042_2326 4.65e-103 301.0 COG1961@1|root,COG1961@2|Bacteria,1UZM8@1239|Firmicutes,4IQ67@91061|Bacilli,42EG7@671232|Streptococcus anginosus group 91061|Bacilli L Resolvase, N terminal domain tnpR - - - - - - - - - - - HTH_23,HTH_7,Resolvase OGLMJJLJ_00264 862969.SCI_0195 0.0 880.0 COG3843@1|root,COG3843@2|Bacteria,1V2SB@1239|Firmicutes,4HFEX@91061|Bacilli,42E61@671232|Streptococcus anginosus group 91061|Bacilli U Relaxase/Mobilisation nuclease domain - - - - - - - - - - - - Relaxase OGLMJJLJ_00265 873447.SPB_0388 8.65e-58 181.0 2DPAH@1|root,3318H@2|Bacteria,1VJAY@1239|Firmicutes,4HR0E@91061|Bacilli 91061|Bacilli S Bacterial mobilisation protein (MobC) - - - - - - - - - - - - MobC OGLMJJLJ_00267 1035184.HMPREF1042_2335 7.98e-165 494.0 COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HN8F@91061|Bacilli,42DXU@671232|Streptococcus anginosus group 91061|Bacilli L Toprim-like - - - - - - - - - - - - DUF3991,Peptidase_M78,Toprim_2 OGLMJJLJ_00268 873447.SPB_0386 1.24e-247 727.0 COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HN8F@91061|Bacilli 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF3991,Peptidase_M78,Toprim_2 OGLMJJLJ_00269 873447.SPB_0385 0.0 951.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim OGLMJJLJ_00271 862969.SCI_0190 0.0 1067.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4HF20@91061|Bacilli,42E83@671232|Streptococcus anginosus group 91061|Bacilli U Type IV secretory system Conjugative DNA transfer - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf OGLMJJLJ_00272 1035184.HMPREF1042_2339 2.76e-83 250.0 2EDAG@1|root,3376W@2|Bacteria,1VIW8@1239|Firmicutes,4HQS8@91061|Bacilli,42EGT@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00273 1035184.HMPREF1042_2340 3.39e-51 177.0 COG3468@1|root,COG3468@2|Bacteria,1UMUJ@1239|Firmicutes,4IU0F@91061|Bacilli,42EFA@671232|Streptococcus anginosus group 91061|Bacilli MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - OGLMJJLJ_00274 1035184.HMPREF1042_2341 1.45e-96 296.0 2DIU0@1|root,3044E@2|Bacteria,1TW0G@1239|Firmicutes,4I4P6@91061|Bacilli,42EHD@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00276 862969.SCI_0185 2.06e-136 387.0 2DNFF@1|root,32X8K@2|Bacteria,1VDM9@1239|Firmicutes,4HNCS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00277 873447.SPB_0377 0.0 1184.0 COG3942@1|root,COG3942@2|Bacteria,1VPFZ@1239|Firmicutes,4HFGV@91061|Bacilli 91061|Bacilli M CHAP domain protein - - - - - - - - - - - - CHAP,Peptidase_M23 OGLMJJLJ_00278 1035184.HMPREF1042_2347 0.0 1407.0 COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,4HC47@91061|Bacilli 91061|Bacilli U Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_10,DUF87 OGLMJJLJ_00281 1035184.HMPREF1042_2350 4.78e-134 384.0 2EFFF@1|root,33986@2|Bacteria,1VY42@1239|Firmicutes,4HMPN@91061|Bacilli,42EEK@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - TrbL OGLMJJLJ_00283 1035184.HMPREF1042_2352 1.78e-53 169.0 COG4443@1|root,COG4443@2|Bacteria 2|Bacteria S Transcriptional Coactivator p15 (PC4) - - - - - - - - - - - - PC4 OGLMJJLJ_00284 1035184.HMPREF1042_2353 1.93e-51 164.0 2DIUA@1|root,3044T@2|Bacteria,1TW11@1239|Firmicutes,4I4PX@91061|Bacilli,42EI4@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00285 862969.SCI_0175 1.28e-126 369.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,42DYE@671232|Streptococcus anginosus group 91061|Bacilli S Replication initiator protein A (RepA) N-terminus repA - - - - - - - - - - - RepA_N OGLMJJLJ_00287 322159.STER_0492 4.05e-224 623.0 COG0760@1|root,COG0760@2|Bacteria 2|Bacteria O peptidyl-prolyl cis-trans isomerase activity prsA - 3.1.3.16,5.2.1.8 ko:K01802,ko:K03769,ko:K07533,ko:K20074 - - - - ko00000,ko01000,ko01009,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 OGLMJJLJ_00288 264199.stu0455 1.38e-163 458.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli 91061|Bacilli S O-Methyltransferase yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 OGLMJJLJ_00289 322159.STER_0489 0.0 1199.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N OGLMJJLJ_00290 322159.STER_0488 3.31e-238 654.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA OGLMJJLJ_00291 904306.HMPREF9192_0361 8.49e-210 580.0 COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli 91061|Bacilli K transcriptional regulator (lysR family) - - - - - - - - - - - - HTH_1,LysR_substrate OGLMJJLJ_00292 264199.stu0451 0.0 1335.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind OGLMJJLJ_00296 322159.STER_0480 6.47e-244 671.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH OGLMJJLJ_00297 264199.stu0446 1.03e-84 253.0 COG1388@1|root,COG1388@2|Bacteria,1V61Q@1239|Firmicutes,4HHT0@91061|Bacilli 91061|Bacilli M LysM domain protein sip - - - - - - - - - - - LysM OGLMJJLJ_00298 264199.stu0442 7.02e-187 536.0 COG1388@1|root,COG3942@1|root,COG1388@2|Bacteria,COG3942@2|Bacteria 2|Bacteria S pathogenesis usp - 3.5.1.104,3.5.1.28 ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409 ko05133,map05133 - - - ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000 1.B.40.2 CBM50 - CHAP,LysM,RHS_repeat OGLMJJLJ_00299 264199.stu0441 3.3e-47 150.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like OGLMJJLJ_00300 322159.STER_0476 3.36e-206 570.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria yitL - - ko:K00243 - - - - ko00000 - - - S1_2 OGLMJJLJ_00301 322159.STER_0475 9.6e-119 340.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF OGLMJJLJ_00302 322159.STER_0474 1.38e-168 471.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase OGLMJJLJ_00303 264199.stu0437 8.72e-99 291.0 COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli 91061|Bacilli T Histidine kinase sptS - - - - - - - - - - - HATPase_c,HisKA OGLMJJLJ_00304 1046629.Ssal_01762 6.54e-58 184.0 COG0454@1|root,COG0456@2|Bacteria,1VF01@1239|Firmicutes,4HPKN@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 OGLMJJLJ_00305 264199.stu0434 0.0 1117.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA2 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_00306 264199.stu0433 0.0 1105.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA1 - - ko:K02021,ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_00307 264199.stu0432 5.15e-100 290.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_27,MarR,MarR_2 OGLMJJLJ_00308 322159.STER_0468 1.3e-90 265.0 COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HGYC@91061|Bacilli 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins def_1 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase OGLMJJLJ_00309 264199.stu0430 0.0 880.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N OGLMJJLJ_00310 264199.stu0429 3.3e-208 578.0 COG1057@1|root,COG3172@1|root,COG1057@2|Bacteria,COG3172@2|Bacteria,1TQ29@1239|Firmicutes,4HBZT@91061|Bacilli 91061|Bacilli H adenylyltransferase nadR - - - - - - - - - - - AAA_28,CTP_transf_like OGLMJJLJ_00311 322159.STER_0465 2.94e-180 501.0 COG1051@1|root,COG1051@2|Bacteria,1TST7@1239|Firmicutes,4HEFP@91061|Bacilli 91061|Bacilli F AdP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX OGLMJJLJ_00312 764298.STRMA_0561 2.24e-27 107.0 COG3247@1|root,COG3247@2|Bacteria,1VK2X@1239|Firmicutes 1239|Firmicutes S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 OGLMJJLJ_00313 322159.STER_0462 0.0 1189.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn OGLMJJLJ_00314 264199.stu0425 3.22e-287 785.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 OGLMJJLJ_00315 264199.stu0424 6.34e-179 498.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N OGLMJJLJ_00316 904306.HMPREF9192_0332 4.81e-96 285.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HVKJ@91061|Bacilli 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV OGLMJJLJ_00317 904306.HMPREF9192_0332 3.86e-78 239.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HVKJ@91061|Bacilli 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV OGLMJJLJ_00318 322159.STER_0458 2.74e-84 248.0 COG4835@1|root,COG4835@2|Bacteria,1VHA6@1239|Firmicutes,4HPTC@91061|Bacilli 91061|Bacilli S cog cog4835 WQ51_03320 - - - - - - - - - - - DUF1149 OGLMJJLJ_00319 322159.STER_0457 1.49e-156 440.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins ydaF_2 - - - - - - - - - - - Acetyltransf_3 OGLMJJLJ_00320 1046629.Ssal_01778 1.55e-61 189.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 OGLMJJLJ_00321 264199.stu0417 1.99e-64 198.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p OGLMJJLJ_00322 1046629.Ssal_01780 1.13e-37 130.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_7 OGLMJJLJ_00323 1046629.Ssal_01780 2.76e-51 167.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_7 OGLMJJLJ_00324 264199.stu0414 0.0 892.0 COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes 1239|Firmicutes M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 gtf2 - - - - - - - - - - - - OGLMJJLJ_00325 322159.STER_0452 0.0 1011.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - - - - - - - - - - - Glycos_transf_1 OGLMJJLJ_00326 264199.stu0412 5.54e-286 782.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI OGLMJJLJ_00327 264199.stu0411 7.87e-266 729.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli 91061|Bacilli E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 OGLMJJLJ_00328 1005705.HMPREF9967_0802 1.8e-06 53.1 2DIXV@1|root,304C8@2|Bacteria,1TWH5@1239|Firmicutes,4I5AH@91061|Bacilli,43G9W@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00329 264199.stu0409 1.8e-308 840.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08370 Mur_ligase_C,Mur_ligase_M OGLMJJLJ_00330 264199.stu0408 0.0 895.0 COG1249@1|root,COG1249@2|Bacteria,1TQFH@1239|Firmicutes,4HCT8@91061|Bacilli 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim OGLMJJLJ_00331 1046629.Ssal_01791 0.0 1176.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli 91061|Bacilli G phosphotransferase system fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB OGLMJJLJ_00332 264199.stu0400 1.85e-211 585.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB OGLMJJLJ_00333 264199.stu0399 5.33e-163 457.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli 91061|Bacilli K transcriptional fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR OGLMJJLJ_00334 264199.stu0398 8.72e-111 319.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00335 264199.stu0397 1.89e-312 860.0 COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli 91061|Bacilli D Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 OGLMJJLJ_00336 1046629.Ssal_01795 6.58e-116 331.0 COG1854@1|root,COG1854@2|Bacteria,1V1V3@1239|Firmicutes,4HFR0@91061|Bacilli 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS OGLMJJLJ_00337 322159.STER_0439 1.88e-176 492.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA OGLMJJLJ_00338 322159.STER_0438 1.4e-203 563.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans OGLMJJLJ_00339 322159.STER_0437 0.0 889.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 OGLMJJLJ_00340 1046629.Ssal_01800 3.4e-93 272.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA OGLMJJLJ_00341 322159.STER_0435 5.95e-95 278.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl OGLMJJLJ_00342 322159.STER_0434 1.83e-297 811.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt OGLMJJLJ_00343 322159.STER_0433 8.26e-165 462.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 OGLMJJLJ_00344 322159.STER_0432 6.7e-211 583.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 OGLMJJLJ_00345 322159.STER_0431 2.27e-221 611.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli 91061|Bacilli S 2-Nitropropane dioxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO OGLMJJLJ_00346 435842.HMPREF0848_00012 1.49e-40 134.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding OGLMJJLJ_00347 322159.STER_0429 1.88e-224 619.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C OGLMJJLJ_00348 904306.HMPREF9192_0286 1.32e-96 281.0 COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4HIMR@91061|Bacilli 91061|Bacilli K Transcriptional regulator, MarR family XK27_02735 - - - - - - - - - - - MarR OGLMJJLJ_00349 264199.stu0380 9.66e-178 496.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family phaB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 - R07639,R09837,R09839 RC00004,RC00326,RC01078,RC02689,RC03003 ko00000,ko00001,ko01000,ko01004 - - - ECH_1 OGLMJJLJ_00350 322159.STER_0426 8.42e-149 419.0 COG0637@1|root,COG0637@2|Bacteria,1V7XM@1239|Firmicutes,4IPJK@91061|Bacilli 91061|Bacilli S Haloacid dehalogenase-like hydrolase - - - - - - - - - - - - HAD_2 OGLMJJLJ_00351 322159.STER_0425 0.0 886.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 OGLMJJLJ_00352 322159.STER_0424 3.09e-244 670.0 COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli 91061|Bacilli E aspartate--ammonia ligase asnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - - AsnA OGLMJJLJ_00353 264199.stu0376 0.0 897.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr OGLMJJLJ_00354 264199.stu0375 3.96e-179 499.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HKE3@91061|Bacilli 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX OGLMJJLJ_00355 264199.stu0374 9.83e-133 375.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 OGLMJJLJ_00356 264199.stu0373 2.13e-139 395.0 2F8BM@1|root,340QP@2|Bacteria,1W4V4@1239|Firmicutes,4HR72@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1803) - - - - - - - - - - - - DUF1803 OGLMJJLJ_00357 322159.STER_0367 1.52e-284 777.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_00358 264199.stu0372 2.85e-214 592.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 OGLMJJLJ_00359 322159.STER_0151 4.16e-298 813.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00366 264199.stu0370 1.8e-117 337.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE OGLMJJLJ_00367 264199.stu0369 3.41e-157 441.0 COG1040@1|root,COG1040@2|Bacteria,1V73S@1239|Firmicutes,4HJ6R@91061|Bacilli 91061|Bacilli S Competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran OGLMJJLJ_00368 322159.STER_0406 0.0 875.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli 91061|Bacilli L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein) comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII OGLMJJLJ_00369 322159.STER_0405 1.91e-143 405.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 OGLMJJLJ_00370 264199.stu0366 2.63e-214 592.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP OGLMJJLJ_00371 264199.stu0365 2.61e-55 173.0 COG0517@1|root,COG0517@2|Bacteria 2|Bacteria S IMP dehydrogenase activity acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS OGLMJJLJ_00372 1046629.Ssal_01826 7.94e-52 168.0 COG0517@1|root,COG0517@2|Bacteria,1V4CD@1239|Firmicutes,4HGX4@91061|Bacilli 91061|Bacilli S CBS domain XK27_04065 - - ko:K04767 - - - - ko00000 - - - ACT,CBS OGLMJJLJ_00373 1046629.Ssal_01828 5.36e-157 441.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli 91061|Bacilli E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran OGLMJJLJ_00374 322159.STER_0401 2.29e-176 492.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C OGLMJJLJ_00375 264199.stu0361 7.76e-183 513.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HDIU@91061|Bacilli 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 OGLMJJLJ_00376 264199.stu0360 8.19e-190 529.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 OGLMJJLJ_00377 264199.stu0359 1.87e-269 739.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli 91061|Bacilli E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 OGLMJJLJ_00378 264199.stu0358 4.33e-62 190.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli 91061|Bacilli S UPF0298 protein ylbG - - - - - - - - - - - DUF2129 OGLMJJLJ_00379 264199.stu0357 2.74e-96 281.0 COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family ylbF - - - - - - - - - - - Com_YlbF OGLMJJLJ_00380 264199.stu0356 1.53e-134 381.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease OGLMJJLJ_00381 264199.stu0355 1.06e-145 410.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase OGLMJJLJ_00382 1046629.Ssal_01837 4.28e-13 70.9 COG1621@1|root,COG1621@2|Bacteria,1TR8C@1239|Firmicutes,4HBYU@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 68 family sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9 ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R04194,R05140 RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 - GH68 - Glyco_hydro_68,Gram_pos_anchor,SH3_8 OGLMJJLJ_00383 264199.stu0353 1.27e-282 772.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities malY - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 OGLMJJLJ_00384 264199.stu0352 1.19e-256 704.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP OGLMJJLJ_00385 1282665.H353_06423 1.37e-109 341.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli 91061|Bacilli P cation transport ATPase pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 OGLMJJLJ_00386 264199.stu0350 0.0 978.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C OGLMJJLJ_00387 264199.stu0349 0.0 944.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli 91061|Bacilli M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M OGLMJJLJ_00388 264199.stu0348 1.81e-279 766.0 COG2348@1|root,COG2348@2|Bacteria,1UZIJ@1239|Firmicutes,4HAQ3@91061|Bacilli 91061|Bacilli V protein involved in methicillin resistance femA - 2.3.2.17 ko:K11694 ko00550,ko01100,map00550,map01100 - R08777 RC00055,RC00096 ko00000,ko00001,ko01000,ko01011 - - - FemAB OGLMJJLJ_00389 904306.HMPREF9192_0063 2.4e-59 188.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HGSU@91061|Bacilli 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox OGLMJJLJ_00390 264199.stu0345 9.81e-77 229.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA OGLMJJLJ_00391 264199.stu0344 0.0 1358.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N OGLMJJLJ_00392 264199.stu0343 2.19e-56 176.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli 91061|Bacilli J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae OGLMJJLJ_00393 264199.stu0342 2.72e-63 193.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli 91061|Bacilli K Nucleic-acid-binding protein implicated in transcription termination ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 OGLMJJLJ_00394 322159.STER_0380 2.28e-270 741.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 OGLMJJLJ_00395 264199.stu0340 3.06e-105 304.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli 91061|Bacilli S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C OGLMJJLJ_00396 264199.stu0339 4.14e-277 759.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli 91061|Bacilli K Transcriptional brpA - - - - - - - - - - - LytR_cpsA_psr OGLMJJLJ_00397 264199.stu0338 6.67e-120 342.0 COG1247@1|root,COG1247@2|Bacteria,1VA2F@1239|Firmicutes 1239|Firmicutes M Acetyltransferase GNAT Family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_4 OGLMJJLJ_00398 264199.stu0337 1.54e-101 294.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli 91061|Bacilli M ATPase or kinase ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE OGLMJJLJ_00399 904306.HMPREF9192_0073 1.13e-307 842.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli 91061|Bacilli S permease XK27_07275 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease OGLMJJLJ_00400 322159.STER_0374 2.82e-194 538.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 OGLMJJLJ_00401 264199.stu0334 8.74e-180 499.0 COG1878@1|root,COG1878@2|Bacteria,1TRBQ@1239|Firmicutes,4HCAB@91061|Bacilli 91061|Bacilli S Metal-dependent hydrolase XK27_00940 - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase OGLMJJLJ_00402 322159.STER_0372 8.03e-231 636.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli 91061|Bacilli G pts system manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb OGLMJJLJ_00403 322159.STER_0371 8.44e-162 457.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli 91061|Bacilli G pts system manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor OGLMJJLJ_00404 264199.stu0331 8.21e-215 593.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli 91061|Bacilli G PTS system mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA OGLMJJLJ_00405 322159.STER_0369 1.52e-81 241.0 COG4687@1|root,COG4687@2|Bacteria,1VF36@1239|Firmicutes,4HPYI@91061|Bacilli 91061|Bacilli S protein conserved in bacteria manO - - - - - - - - - - - DUF956 OGLMJJLJ_00406 264199.stu0329 2.31e-306 836.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b OGLMJJLJ_00410 1116231.SMA_0321 7.76e-135 388.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_00411 904306.HMPREF9192_0086 1.97e-116 335.0 COG1335@1|root,COG1335@2|Bacteria,1V70H@1239|Firmicutes,4HJXC@91061|Bacilli 91061|Bacilli Q isochorismatase yrdC - - - - - - - - - - - Isochorismatase OGLMJJLJ_00412 322159.STER_0359 4.84e-313 853.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 OGLMJJLJ_00413 264199.stu0321 1.53e-213 590.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 OGLMJJLJ_00414 264199.stu0320 3.02e-275 753.0 COG3611@1|root,COG3611@2|Bacteria 2|Bacteria L Replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 OGLMJJLJ_00415 264199.stu0319 1.46e-106 308.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone OGLMJJLJ_00416 264199.stu0318 0.0 961.0 COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,4HWKS@91061|Bacilli 91061|Bacilli T Histidine kinase covS - - - - - - - - - - - HAMP,HATPase_c,HisKA OGLMJJLJ_00417 264199.stu0317 1.55e-157 442.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli 91061|Bacilli T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain csrR - - - - - - - - - - - Response_reg,Trans_reg_C OGLMJJLJ_00418 322159.STER_0353 1.62e-118 339.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli 91061|Bacilli K metal-binding, possibly nucleic acid-binding protein ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 OGLMJJLJ_00419 264199.stu0315 2.13e-168 470.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli 91061|Bacilli J Ribosomal RNA small subunit methyltransferase G rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB OGLMJJLJ_00420 322159.STER_0351 8.59e-307 838.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH OGLMJJLJ_00421 264199.stu0313 2.81e-157 441.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli 91061|Bacilli P COG0569 K transport systems, NAD-binding component ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N OGLMJJLJ_00422 1123298.KB904063_gene687 2.41e-15 76.6 COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,4HBNW@91061|Bacilli 91061|Bacilli S L-ascorbate 6-phosphate lactonase ulaG - - ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 M00550 R07677 RC02793 ko00000,ko00001,ko00002,ko01000 - - - Lactamase_B_2,Lactamase_B_3 OGLMJJLJ_00423 264199.stu0312 0.0 1308.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N OGLMJJLJ_00424 322159.STER_0348 3.54e-191 531.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ OGLMJJLJ_00425 322159.STER_0347 0.0 1082.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli 91061|Bacilli P abc transporter atp-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 OGLMJJLJ_00426 322159.STER_0346 5.41e-123 351.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS OGLMJJLJ_00427 322159.STER_0345 1.25e-203 563.0 COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli 91061|Bacilli S S-adenosyl-l-methionine hydroxide adenosyltransferase ilvH - - - - - - - - - - - SAM_adeno_trans OGLMJJLJ_00428 264199.stu0303 3.61e-268 736.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli 91061|Bacilli E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF OGLMJJLJ_00429 264199.stu0302 7.21e-143 405.0 COG2011@1|root,COG2011@2|Bacteria,1V0GE@1239|Firmicutes,4HFMB@91061|Bacilli 91061|Bacilli P ABC transporter (Permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 OGLMJJLJ_00430 264199.stu0301 8.82e-243 668.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL OGLMJJLJ_00431 264199.stu0300 1.09e-79 237.0 COG0624@1|root,COG0624@2|Bacteria 2|Bacteria E succinyl-diaminopimelate desuccinylase activity dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 OGLMJJLJ_00432 904306.HMPREF9192_0106 3.11e-94 286.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli 91061|Bacilli E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 OGLMJJLJ_00433 264199.stu0298 6.88e-101 293.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli 91061|Bacilli E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 OGLMJJLJ_00434 264199.stu0297 1.16e-208 577.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli 91061|Bacilli M Belongs to the NlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 OGLMJJLJ_00435 1046629.Ssal_00039 1.11e-63 205.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00436 322159.STER_0151 4.78e-206 575.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00437 264199.stu0296 9.07e-197 546.0 COG0834@1|root,COG0834@2|Bacteria 2|Bacteria ET amino acid transport - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_00438 264199.stu0294 7.28e-268 736.0 COG0477@1|root,COG0477@2|Bacteria,1UHQE@1239|Firmicutes 1239|Firmicutes EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1,MFS_3 OGLMJJLJ_00439 264199.stu0293 0.0 1089.0 COG0499@1|root,COG1051@1|root,COG0499@2|Bacteria,COG1051@2|Bacteria,1V1P7@1239|Firmicutes,4HFQH@91061|Bacilli 91061|Bacilli F NUDIX domain - - - - - - - - - - - - AdoHcyase_NAD,NUDIX OGLMJJLJ_00440 264199.stu0292 0.0 1867.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,KR,PP-binding,Thioesterase,adh_short OGLMJJLJ_00441 322159.STER_0333 4.31e-195 541.0 COG0834@1|root,COG0834@2|Bacteria 2|Bacteria ET amino acid transport - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_00442 264199.stu0290 3.03e-168 470.0 COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,4HI15@91061|Bacilli 91061|Bacilli P ABC transporter - - - ko:K02006 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - ABC_tran OGLMJJLJ_00443 264199.stu0289 1.87e-173 485.0 COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes 1239|Firmicutes P cobalt transport protein nikQ - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ OGLMJJLJ_00444 322159.STER_0330 1.67e-225 622.0 COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,4HARY@91061|Bacilli 91061|Bacilli P PDGLE domain cbiM - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE OGLMJJLJ_00445 264199.stu0287 1.78e-206 570.0 COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,4HCED@91061|Bacilli 91061|Bacilli O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD OGLMJJLJ_00446 1046629.Ssal_01896 4.71e-142 401.0 COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,4HC5C@91061|Bacilli 91061|Bacilli KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW OGLMJJLJ_00447 264199.stu0285 1.83e-169 473.0 COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,4HKQE@91061|Bacilli 91061|Bacilli O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF OGLMJJLJ_00448 1046629.Ssal_01898 2.74e-101 293.0 COG2371@1|root,COG2371@2|Bacteria 2|Bacteria O enzyme active site formation ureE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N OGLMJJLJ_00449 904306.HMPREF9192_0116 0.0 1154.0 COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,4HBTS@91061|Bacilli 91061|Bacilli E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha OGLMJJLJ_00450 1046629.Ssal_01901 1.54e-71 214.0 COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,4HM0I@91061|Bacilli 91061|Bacilli E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta OGLMJJLJ_00451 264199.stu0281 1.02e-61 189.0 COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,4HIJS@91061|Bacilli 91061|Bacilli E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iSB619.SA_RS11965,iYO844.BSU36660 Urease_gamma OGLMJJLJ_00452 264199.stu0280 2.53e-123 351.0 29DTM@1|root,300RH@2|Bacteria,1VAKB@1239|Firmicutes 1239|Firmicutes S AmiS/UreI family transporter ureI - - ko:K03191 ko05120,map05120 - - - ko00000,ko00001,ko02000 1.A.29.1.3,1.A.29.1.4,1.A.29.1.5 - - AmiS_UreI OGLMJJLJ_00453 1046629.Ssal_01904 2.14e-69 222.0 2E26M@1|root,32XD2@2|Bacteria,1VCM1@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4173) - - - - - - - - - - - - DUF4173 OGLMJJLJ_00454 1046629.Ssal_01905 1.66e-40 136.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane yhaI - - - - - - - - - - - DUF805 OGLMJJLJ_00455 904306.HMPREF9192_0124 1.44e-107 320.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA - - ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_00456 1046629.Ssal_01906 1.01e-90 285.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA - - ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_00457 264199.stu0272 2.45e-141 400.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA - - ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_00458 264199.stu0271 3.36e-46 148.0 COG2274@1|root,COG2274@2|Bacteria 2|Bacteria V protein secretion by the type I secretion system - GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_00459 264199.stu0270 5.93e-206 570.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20342,ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_19,HTH_3 OGLMJJLJ_00460 264199.stu0269 1.23e-143 406.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli 91061|Bacilli I Membrane-associated phospholipid phosphatase yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 OGLMJJLJ_00461 264199.stu0268 3.96e-117 337.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt OGLMJJLJ_00462 264199.stu0267 1.34e-125 357.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase OGLMJJLJ_00463 264199.stu0265 1.1e-311 850.0 COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,4HCRM@91061|Bacilli 91061|Bacilli P Potassium transporter peripheral membrane component trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N OGLMJJLJ_00464 264199.stu0264 0.0 890.0 COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,4HCWN@91061|Bacilli 91061|Bacilli P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH OGLMJJLJ_00465 264199.stu0263 1.05e-53 168.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic OGLMJJLJ_00466 264199.stu0262 3.14e-179 499.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 OGLMJJLJ_00467 264199.stu0261 7.56e-129 367.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB OGLMJJLJ_00468 264199.stu0260 9.6e-156 438.0 COG1354@1|root,COG1354@2|Bacteria,1V8JV@1239|Firmicutes,4IQZ5@91061|Bacilli 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA OGLMJJLJ_00469 264199.stu0259 4.14e-175 489.0 COG4974@1|root,COG4974@2|Bacteria,1VY7C@1239|Firmicutes,4IT0W@91061|Bacilli 91061|Bacilli L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site xerD - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase OGLMJJLJ_00470 322159.STER_0305 2.04e-110 317.0 COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS OGLMJJLJ_00471 264199.stu0257 7.82e-128 362.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 OGLMJJLJ_00472 264199.stu0256 1.64e-236 650.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like OGLMJJLJ_00473 322159.STER_0302 5.43e-188 523.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race OGLMJJLJ_00474 264199.stu0254 5.74e-48 153.0 COG3763@1|root,COG3763@2|Bacteria,1VDSU@1239|Firmicutes,4HM8G@91061|Bacilli 91061|Bacilli S UPF0154 protein - - - ko:K09976 - - - - ko00000 - - - UPF0154 OGLMJJLJ_00475 322159.STER_0300 7.11e-118 338.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_N OGLMJJLJ_00476 264199.stu0252 4.07e-310 844.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC OGLMJJLJ_00479 322159.STER_0296 2e-144 409.0 COG0670@1|root,COG0670@2|Bacteria,1V779@1239|Firmicutes,4HIX1@91061|Bacilli 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I OGLMJJLJ_00480 322159.STER_0295 5.81e-121 344.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli 91061|Bacilli S HD superfamily hydrolase XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD OGLMJJLJ_00481 264199.stu0247 2.78e-168 471.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind OGLMJJLJ_00482 264199.stu0246 3.88e-60 185.0 COG1254@1|root,COG1254@2|Bacteria 2|Bacteria C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020,iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036 Acylphosphatase OGLMJJLJ_00483 264199.stu0245 1.52e-211 585.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP OGLMJJLJ_00484 322159.STER_0291 3.12e-115 330.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_00485 322159.STER_0289 2.36e-100 292.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N OGLMJJLJ_00486 322159.STER_0288 0.0 1198.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli 91061|Bacilli ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG OGLMJJLJ_00487 264199.stu0240 6.64e-68 207.0 COG0454@1|root,COG0454@2|Bacteria 2|Bacteria K -acetyltransferase XK27_09675 - - ko:K07105 - - - - ko00000 - - - Acetyltransf_1,Acetyltransf_10 OGLMJJLJ_00488 264199.stu0239 0.0 882.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M OGLMJJLJ_00489 1214166.ALLG01000002_gene1746 5.18e-27 110.0 2BTGZ@1|root,32NPB@2|Bacteria,1U91J@1239|Firmicutes,4IJ1N@91061|Bacilli,1WTEE@1307|Streptococcus suis 91061|Bacilli - - XK27_11680 - - - - - - - - - - - - OGLMJJLJ_00490 322159.STER_0284 0.0 2021.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli 91061|Bacilli L Superfamily II DNA RNA helicases, SNF2 family' snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM OGLMJJLJ_00491 322159.STER_0283 0.0 1113.0 2DB6P@1|root,32TWV@2|Bacteria,1VDPS@1239|Firmicutes,4HK8Y@91061|Bacilli 91061|Bacilli D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning mapZ - - ko:K20073 - - - - ko00000 - - - - OGLMJJLJ_00492 264199.stu0234 2.51e-282 771.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 OGLMJJLJ_00493 264199.stu0233 1.97e-66 202.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HKUX@91061|Bacilli 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA OGLMJJLJ_00494 322159.STER_0279 8.82e-124 352.0 COG4474@1|root,COG4474@2|Bacteria,1V5Q7@1239|Firmicutes,4HECZ@91061|Bacilli 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 OGLMJJLJ_00495 264199.stu0231 1.72e-141 399.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU OGLMJJLJ_00496 264199.stu0230 0.0 1387.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 OGLMJJLJ_00497 264199.stu0229 0.0 892.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli 91061|Bacilli E aminopeptidase pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 OGLMJJLJ_00498 264199.stu0228 1.37e-99 289.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane yhaI - - - - - - - - - - - DUF805 OGLMJJLJ_00499 264199.stu0227 6.15e-195 540.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli 91061|Bacilli H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase OGLMJJLJ_00500 264199.stu0226 0.0 945.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase OGLMJJLJ_00501 1095726.HMPREF1116_1200 1.69e-158 452.0 COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,4HE7V@91061|Bacilli 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Bile_Hydr_Trans OGLMJJLJ_00502 1046629.Ssal_01959 7.76e-30 115.0 COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,4HE7V@91061|Bacilli 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Bile_Hydr_Trans OGLMJJLJ_00504 264199.stu0220 0.0 1702.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 OGLMJJLJ_00505 264199.stu0219 1.04e-126 363.0 COG1349@1|root,COG1349@2|Bacteria,1V6VV@1239|Firmicutes,4HK1E@91061|Bacilli 91061|Bacilli K transcriptional regulator (DeoR family) - - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR OGLMJJLJ_00506 264199.stu0218 3.26e-48 154.0 COG0561@1|root,COG0561@2|Bacteria 2|Bacteria Q phosphatase activity cof - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_00507 264199.stu0217 8.94e-63 192.0 COG0561@1|root,COG0561@2|Bacteria 2|Bacteria Q phosphatase activity cof - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_00508 264199.stu0216 1.17e-110 318.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 - R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 - - - PAP2 OGLMJJLJ_00509 1046629.Ssal_01967 2.8e-124 354.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG OGLMJJLJ_00510 904306.HMPREF9192_0204 3.64e-34 117.0 COG0690@1|root,COG0690@2|Bacteria,1W4QH@1239|Firmicutes 1239|Firmicutes U Belongs to the SecE SEC61-gamma family secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE OGLMJJLJ_00511 264199.stu0213 4.01e-30 106.0 COG0267@1|root,COG0267@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 OGLMJJLJ_00512 264199.stu0212 0.0 1503.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase OGLMJJLJ_00513 264199.stu0211 2.26e-210 581.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 OGLMJJLJ_00514 322159.STER_0258 1.55e-72 218.0 COG2314@1|root,COG2314@2|Bacteria,1VKEZ@1239|Firmicutes,4HS74@91061|Bacilli 91061|Bacilli S TM2 domain WQ51_06355 - - - - - - - - - - - TM2 OGLMJJLJ_00515 435842.HMPREF0848_01529 3.02e-23 90.5 2C0H5@1|root,2ZRTJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2752 OGLMJJLJ_00518 264199.stu0207 8.09e-44 142.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_00519 264199.stu0018 1.32e-64 199.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_00520 1095738.HMPREF1047_1210 1.6e-22 91.3 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - HTH_Tnp_1 OGLMJJLJ_00521 322159.STER_0016 1.18e-79 239.0 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - HTH_Tnp_1 OGLMJJLJ_00522 264199.stu0204 0.0 984.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 OGLMJJLJ_00523 264199.stu0203 2.13e-55 173.0 COG0234@1|root,COG0234@2|Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 OGLMJJLJ_00524 264199.stu0202 1.43e-181 506.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein cmpC - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran OGLMJJLJ_00525 264199.stu0201 0.0 1169.0 COG2984@1|root,COG4120@1|root,COG2984@2|Bacteria,COG4120@2|Bacteria,1TPB0@1239|Firmicutes 1239|Firmicutes S ABC transporter substrate binding protein XK27_00665 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind OGLMJJLJ_00526 264199.stu0200 0.0 1199.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit OGLMJJLJ_00527 322159.STER_0246 9.01e-294 803.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 OGLMJJLJ_00528 264199.stu0198 5.24e-187 520.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 OGLMJJLJ_00529 264199.stu0197 2.06e-181 504.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf OGLMJJLJ_00530 264199.stu0196 4.41e-64 196.0 COG1862@1|root,COG1862@2|Bacteria 2|Bacteria U protein transport yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC OGLMJJLJ_00531 264199.stu0195 3.92e-163 457.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli 91061|Bacilli K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg OGLMJJLJ_00532 264199.stu0194 0.0 880.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI OGLMJJLJ_00533 264199.stu0193 6.69e-200 553.0 COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,4HGS5@91061|Bacilli 91061|Bacilli L Endonuclease/Exonuclease/phosphatase family rgfB - 3.1.3.90 ko:K06896 ko00500,map00500 - R10486 RC00017 ko00000,ko00001,ko01000 - - - Exo_endo_phos OGLMJJLJ_00534 435842.HMPREF0848_01513 0.0 904.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli 91061|Bacilli G pts system ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC OGLMJJLJ_00535 435842.HMPREF0848_01513 8.33e-30 117.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli 91061|Bacilli G pts system ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC OGLMJJLJ_00536 264199.stu0189 5.05e-86 254.0 COG1263@1|root,COG1263@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli 91061|Bacilli G pts system ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC OGLMJJLJ_00537 264199.stu0188 2.93e-208 577.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans OGLMJJLJ_00538 322159.STER_0235 7.36e-165 464.0 COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli 91061|Bacilli P ABC transporter (Permease adcB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 OGLMJJLJ_00539 264199.stu0186 8.76e-176 489.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli 91061|Bacilli P ABC transporter, ATP-binding protein adcC - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran OGLMJJLJ_00540 264199.stu0185 1.28e-94 276.0 COG1846@1|root,COG1846@2|Bacteria,1VXZT@1239|Firmicutes,4HXMU@91061|Bacilli 91061|Bacilli K transcriptional adcR - - - - - - - - - - - HTH_27,MarR OGLMJJLJ_00541 264199.stu0184 1.03e-284 780.0 COG0477@1|root,2ZBIK@2|Bacteria,1UG5D@1239|Firmicutes,4H9W5@91061|Bacilli 91061|Bacilli EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1 OGLMJJLJ_00542 264199.stu0183 0.0 1562.0 COG0515@1|root,COG0515@2|Bacteria,1V7E2@1239|Firmicutes,4HJ1U@91061|Bacilli 91061|Bacilli KLT serine threonine protein kinase - - - - - - - - - - - - LANC_like,Pkinase OGLMJJLJ_00543 264199.stu0182 3.55e-162 457.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20374,ko:K21405 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3 OGLMJJLJ_00544 322159.STER_0231 2.41e-234 644.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus OGLMJJLJ_00545 322159.STER_0230 9.47e-202 559.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 OGLMJJLJ_00546 1123311.KB904471_gene1168 3.89e-14 69.3 2DCPN@1|root,2ZEV1@2|Bacteria,1W24H@1239|Firmicutes,4HZKX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00547 1123311.KB904471_gene1168 2.04e-05 44.7 2DCPN@1|root,2ZEV1@2|Bacteria,1W24H@1239|Firmicutes,4HZKX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00548 264199.stu0178 1.76e-117 342.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_00549 264199.stu0178 7.08e-78 239.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4H9YB@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily oppF - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_00550 264199.stu0177 4.16e-58 180.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily oppD - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_00551 264199.stu0176 9.75e-90 263.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily - - - ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_00552 264199.stu0175 1.15e-43 141.0 COG0444@1|root,COG0444@2|Bacteria 2|Bacteria P Belongs to the ABC transporter superfamily oppD - - ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_00553 264199.stu0174 9.63e-38 127.0 COG0444@1|root,COG0444@2|Bacteria 2|Bacteria P Belongs to the ABC transporter superfamily oppD - - ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_00554 264199.stu0173 3.42e-50 161.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N OGLMJJLJ_00555 1046629.Ssal_02002 3.48e-12 65.1 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H9PZ@91061|Bacilli 91061|Bacilli EP ABC-type dipeptide oligopeptide nickel transport systems, permease components oppC - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N OGLMJJLJ_00557 1046629.Ssal_02003 1.6e-36 129.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HA2S@91061|Bacilli 91061|Bacilli P ABC-type dipeptide oligopeptide nickel transport systems, permease components oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 OGLMJJLJ_00558 264199.stu0170 2.28e-170 478.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 OGLMJJLJ_00559 435842.HMPREF0848_01501 4.23e-23 98.2 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli 91061|Bacilli E ABC transporter substrate-binding protein oppA - - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 OGLMJJLJ_00560 264199.stu0168 0.0 944.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 OGLMJJLJ_00561 264199.stu0167 2.39e-96 281.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N OGLMJJLJ_00562 264199.stu0166 9.85e-302 822.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 OGLMJJLJ_00563 322159.STER_0219 5.93e-299 816.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli 91061|Bacilli O assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 OGLMJJLJ_00564 264199.stu0164 1.82e-184 513.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli 91061|Bacilli O ABC-type transport system involved in Fe-S cluster assembly, ATPase component sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran OGLMJJLJ_00565 264199.stu0163 5.68e-245 676.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli 91061|Bacilli M transferase tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 OGLMJJLJ_00566 322159.STER_0216 5.6e-170 475.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA OGLMJJLJ_00567 322159.STER_0215 1.24e-195 543.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA OGLMJJLJ_00568 322159.STER_0214 0.0 971.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli 91061|Bacilli P ABC transporter XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 OGLMJJLJ_00569 264199.stu0158 3e-168 471.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran OGLMJJLJ_00571 1046629.Ssal_02017 7.59e-10 58.9 COG1196@1|root,COG1196@2|Bacteria,1VXI0@1239|Firmicutes,4HMHC@91061|Bacilli 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Gram_pos_anchor OGLMJJLJ_00572 264199.stu0155 8.47e-126 359.0 COG4767@1|root,COG4767@2|Bacteria 2|Bacteria V VanZ like family - - - - - - - - - - - - VanZ OGLMJJLJ_00573 264199.stu0154 1.74e-57 178.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 OGLMJJLJ_00574 322159.STER_0207 1.43e-255 703.0 COG2807@1|root,COG2807@2|Bacteria,1TSM5@1239|Firmicutes,4HF98@91061|Bacilli 91061|Bacilli P Major Facilitator XK27_00055 - - - - - - - - - - - MFS_1 OGLMJJLJ_00575 322159.STER_0206 2.7e-145 410.0 COG0664@1|root,COG0664@2|Bacteria,1V2AH@1239|Firmicutes,4HFNC@91061|Bacilli 91061|Bacilli K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding OGLMJJLJ_00576 264199.stu0151 1.71e-144 407.0 COG0242@1|root,COG0242@2|Bacteria,1V5C6@1239|Firmicutes,4HGUI@91061|Bacilli 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase OGLMJJLJ_00577 322159.STER_0204 3.71e-300 818.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C OGLMJJLJ_00578 1046629.Ssal_02025 3.28e-54 189.0 COG5297@1|root,COG5297@2|Bacteria,1TS2G@1239|Firmicutes,4HF5J@91061|Bacilli 91061|Bacilli G Glycosyl hydrolase family 66 dex - 3.2.1.11 ko:K05988 ko00500,map00500 - R11309 - ko00000,ko00001,ko01000 - GH66 - CBM_35,Glyco_hydro_66,Gram_pos_anchor,SLH OGLMJJLJ_00579 1046629.Ssal_02025 9.76e-23 96.7 COG5297@1|root,COG5297@2|Bacteria,1TS2G@1239|Firmicutes,4HF5J@91061|Bacilli 91061|Bacilli G Glycosyl hydrolase family 66 dex - 3.2.1.11 ko:K05988 ko00500,map00500 - R11309 - ko00000,ko00001,ko01000 - GH66 - CBM_35,Glyco_hydro_66,Gram_pos_anchor,SLH OGLMJJLJ_00580 1046629.Ssal_02025 1.93e-33 129.0 COG5297@1|root,COG5297@2|Bacteria,1TS2G@1239|Firmicutes,4HF5J@91061|Bacilli 91061|Bacilli G Glycosyl hydrolase family 66 dex - 3.2.1.11 ko:K05988 ko00500,map00500 - R11309 - ko00000,ko00001,ko01000 - GH66 - CBM_35,Glyco_hydro_66,Gram_pos_anchor,SLH OGLMJJLJ_00581 1046629.Ssal_02025 1.79e-11 64.3 COG5297@1|root,COG5297@2|Bacteria,1TS2G@1239|Firmicutes,4HF5J@91061|Bacilli 91061|Bacilli G Glycosyl hydrolase family 66 dex - 3.2.1.11 ko:K05988 ko00500,map00500 - R11309 - ko00000,ko00001,ko01000 - GH66 - CBM_35,Glyco_hydro_66,Gram_pos_anchor,SLH OGLMJJLJ_00582 264199.stu0146 2.35e-96 281.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase OGLMJJLJ_00583 322159.STER_0200 0.0 1446.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS OGLMJJLJ_00584 264199.stu0144 3.37e-108 312.0 COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI OGLMJJLJ_00585 322159.STER_0198 1.66e-302 844.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH OGLMJJLJ_00586 322159.STER_0198 1.96e-117 361.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH OGLMJJLJ_00587 322159.STER_0198 4.68e-62 212.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH OGLMJJLJ_00588 322159.STER_0197 1.23e-172 482.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA OGLMJJLJ_00589 264199.stu0137 1.22e-223 617.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA OGLMJJLJ_00590 322159.STER_0195 7.02e-51 163.0 COG0494@1|root,COG0494@2|Bacteria,1V8D5@1239|Firmicutes,4HJKW@91061|Bacilli 91061|Bacilli L NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX OGLMJJLJ_00591 862969.SCI_0845 1.63e-214 607.0 COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,4I4BM@91061|Bacilli,42E4Z@671232|Streptococcus anginosus group 91061|Bacilli L Resolvase, N terminal domain - - - - - - - - - - - - Recombinase,Resolvase OGLMJJLJ_00592 1154860.SAG0136_01735 9.51e-237 668.0 COG1961@1|root,COG1961@2|Bacteria,1TQ8Y@1239|Firmicutes 1239|Firmicutes L Resolvase, N-terminal domain protein - - - - - - - - - - - - Recombinase,Resolvase OGLMJJLJ_00593 1154860.SAG0136_01740 7.85e-297 819.0 COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes 1239|Firmicutes L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF4368,Recombinase,Resolvase,Zn_ribbon_recom OGLMJJLJ_00595 679192.HMPREF9013_1234 7.57e-23 94.0 COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes,3VS77@526524|Erysipelotrichia 526524|Erysipelotrichia K Psort location Cytoplasmic, score - - - - - - - - - - - - Sigma70_r4 OGLMJJLJ_00597 996306.SSUR61_1652 8.81e-101 299.0 COG1266@1|root,COG1266@2|Bacteria,1VFRX@1239|Firmicutes,4HPZB@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi OGLMJJLJ_00598 996306.SSUR61_0113 3.09e-66 220.0 2DWQH@1|root,341F6@2|Bacteria,1W6SH@1239|Firmicutes,4HX74@91061|Bacilli 91061|Bacilli - - blpT - - - - - - - - - - - Thioredoxin OGLMJJLJ_00599 1123298.KB904062_gene930 6.09e-96 285.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_00600 862970.SAIN_0559 5.69e-42 146.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli,42E57@671232|Streptococcus anginosus group 91061|Bacilli L Integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_00601 1123303.AQVD01000001_gene559 9.17e-98 288.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_28,HTH_Tnp_1,rve OGLMJJLJ_00602 1336234.JAGN01000082_gene1255 4.71e-06 46.6 2DH02@1|root,2ZXXA@2|Bacteria,1W3X3@1239|Firmicutes,4I0GW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00603 40041.SZO_04310 1.89e-23 92.0 2DZ2R@1|root,34C7V@2|Bacteria,1W3RP@1239|Firmicutes,4HZZT@91061|Bacilli 91061|Bacilli S Bacteriocin class II with double-glycine leader peptide - - - - - - - - - - - - Bacteriocin_IIc OGLMJJLJ_00604 1005704.HMPREF9968_1217 1.15e-22 96.7 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,1WNWP@1303|Streptococcus oralis 91061|Bacilli V Papain-like cysteine protease AvrRpt2 comA - - ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.112 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_00605 1123304.AQYA01000033_gene1929 0.0 1128.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA - - ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.112 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_00606 759913.SDSE_0544 9.62e-194 552.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli,1M9WQ@119603|Streptococcus dysgalactiae group 91061|Bacilli M HlyD family secretion protein mesE - - ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1 - - HlyD_3 OGLMJJLJ_00608 1336234.JAGN01000013_gene191 2.39e-153 443.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4I3H2@91061|Bacilli,27HJV@186828|Carnobacteriaceae 91061|Bacilli T GHKL domain - - - - - - - - - - - - HATPase_c_5 OGLMJJLJ_00609 1321372.AQQB01000055_gene1644 4.57e-133 382.0 COG3279@1|root,COG3279@2|Bacteria,1U92Z@1239|Firmicutes,4IJ3N@91061|Bacilli,1WTMJ@1307|Streptococcus suis 91061|Bacilli KT LytTr DNA-binding domain - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg OGLMJJLJ_00610 1123304.AQYA01000033_gene1936 2.73e-22 91.3 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system - - - ko:K02477,ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg OGLMJJLJ_00612 1154860.SAG0136_01820 0.0 1041.0 COG3843@1|root,COG3843@2|Bacteria,1V2SB@1239|Firmicutes,4HFEX@91061|Bacilli 91061|Bacilli U relaxase - - - - - - - - - - - - Relaxase,Streptin-Immun OGLMJJLJ_00613 996306.SSUR61_1123 1.08e-66 204.0 2BFHJ@1|root,329BC@2|Bacteria,1U93J@1239|Firmicutes,4IJ4C@91061|Bacilli,1WTP2@1307|Streptococcus suis 91061|Bacilli S Bacterial mobilisation protein (MobC) - - - - - - - - - - - - MobC OGLMJJLJ_00614 996306.SSUR61_1124 1.48e-68 208.0 2BWBR@1|root,2ZDFR@2|Bacteria,1W52Y@1239|Firmicutes,4I0XT@91061|Bacilli,1WTSJ@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00615 158189.SpiBuddy_2398 3.14e-60 199.0 COG1715@1|root,COG1715@2|Bacteria 2|Bacteria V Restriction endonuclease - - - - - - - - - - - - Mrr_cat OGLMJJLJ_00616 525254.HMPREF0072_2204 7.51e-227 680.0 COG1204@1|root,COG1204@2|Bacteria,1U9TG@1239|Firmicutes,25FHQ@186801|Clostridia 186801|Clostridia L DEAD DEAH box helicase - - - - - - - - - - - - DEAD OGLMJJLJ_00617 519441.Smon_0661 1.24e-44 159.0 2C2MI@1|root,2ZBMN@2|Bacteria 2|Bacteria - - vrlR - - - - - - - - - - - DUF1837 OGLMJJLJ_00618 482234.SCAZ3_06005 8.8e-167 468.0 COG0542@1|root,COG0542@2|Bacteria,1V4WZ@1239|Firmicutes,4HKUZ@91061|Bacilli 91061|Bacilli O Zeta toxin - - 2.7.1.176 ko:K16214 - - - - ko00000,ko01000,ko02048 - - - Zeta_toxin OGLMJJLJ_00619 1214166.ALLG01000002_gene1720 0.0 970.0 COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4H9V9@91061|Bacilli,1WTYV@1307|Streptococcus suis 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6,DUF772 OGLMJJLJ_00620 391295.SSU05_0938 2.1e-52 166.0 2BV34@1|root,32QG3@2|Bacteria,1U93B@1239|Firmicutes,4IJ43@91061|Bacilli,1WTNM@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00621 1214166.ALLG01000025_gene1206 5.85e-77 230.0 2AMA9@1|root,31C58@2|Bacteria,1U91T@1239|Firmicutes,4IJ22@91061|Bacilli,1WTG8@1307|Streptococcus suis 91061|Bacilli - - XK27_10880 - - - - - - - - - - - - OGLMJJLJ_00622 1214166.ALLG01000025_gene1207 3.95e-32 113.0 2BFJD@1|root,329DD@2|Bacteria,1U946@1239|Firmicutes,4IJ55@91061|Bacilli,1WTQH@1307|Streptococcus suis 91061|Bacilli - - XK27_10875 - - - - - - - - - - - - OGLMJJLJ_00623 1214217.ALNF01000037_gene354 3.23e-190 533.0 COG0358@1|root,COG0358@2|Bacteria,1TRTK@1239|Firmicutes,4HK3Y@91061|Bacilli,1WT2U@1307|Streptococcus suis 91061|Bacilli L Toprim-like - - - - - - - - - - - - DUF3991,Toprim_2 OGLMJJLJ_00624 1154860.SAG0136_11645 2.65e-15 75.1 COG0358@1|root,COG0358@2|Bacteria,1TRTK@1239|Firmicutes,4HK3Y@91061|Bacilli 91061|Bacilli L Protein of unknown function (DUF3991) - - - - - - - - - - - - DUF3991,Toprim_2 OGLMJJLJ_00625 663952.SDD27957_05275 1.27e-134 383.0 2DCG5@1|root,2ZE0K@2|Bacteria 2|Bacteria - - XK27_10865 - - - - - - - - - - - - OGLMJJLJ_00626 1464048.JNZS01000015_gene3794 1.19e-09 67.4 COG1403@1|root,COG1403@2|Bacteria,2IMU2@201174|Actinobacteria 201174|Actinobacteria V HNH endonuclease - - - - - - - - - - - - - OGLMJJLJ_00627 1302863.I872_10320 3.59e-53 195.0 COG3593@1|root,COG3593@2|Bacteria 2|Bacteria L DNA synthesis involved in DNA repair - - - - - - - - - - - - AAA_15,AAA_21 OGLMJJLJ_00628 1214217.ALNF01000037_gene359 1.39e-42 141.0 2AMFB@1|root,31CAV@2|Bacteria,1U94C@1239|Firmicutes,4IJ5B@91061|Bacilli,1WTR0@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00629 996306.SSUR61_1133 2.16e-58 181.0 29R24@1|root,30C38@2|Bacteria,1U93N@1239|Firmicutes,4IJ4F@91061|Bacilli,1WTP6@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00630 1214166.ALLG01000025_gene1222 1.43e-282 835.0 COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,4HDHN@91061|Bacilli,1WSVK@1307|Streptococcus suis 91061|Bacilli L SNF2 family N-terminal domain XK27_00500 - - - - - - - - - - - Helicase_C,N6_Mtase,SNF2_N OGLMJJLJ_00631 1154860.SAG0136_11725 0.0 1168.0 COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,4H9NW@91061|Bacilli 91061|Bacilli L reverse transcriptase - - - - - - - - - - - - Intron_maturas2,RVT_1 OGLMJJLJ_00632 391295.SSU05_0962 0.0 3428.0 COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,4HDHN@91061|Bacilli,1WSVK@1307|Streptococcus suis 91061|Bacilli L SNF2 family N-terminal domain XK27_00500 - - - - - - - - - - - Helicase_C,N6_Mtase,SNF2_N OGLMJJLJ_00633 996306.SSUR61_1139 7.91e-117 335.0 2BQP9@1|root,32JJP@2|Bacteria,1U906@1239|Firmicutes,4IJ00@91061|Bacilli,1WT7S@1307|Streptococcus suis 91061|Bacilli - - XK27_00505 - - - - - - - - - - - - OGLMJJLJ_00634 996306.SSUR61_1140 3.39e-21 84.7 29R2E@1|root,30C3I@2|Bacteria,1U94D@1239|Firmicutes,4IJ5D@91061|Bacilli,1WTR2@1307|Streptococcus suis 91061|Bacilli - - XK27_00510 - - - - - - - - - - - - OGLMJJLJ_00635 1123315.AUIP01000021_gene2251 0.0 2954.0 COG3087@1|root,COG3087@2|Bacteria,1TSVF@1239|Firmicutes,4HGKU@91061|Bacilli 91061|Bacilli D Glucan-binding protein C XK27_00515 - - - - - - - - - - - Antigen_C,GbpC,Gram_pos_anchor OGLMJJLJ_00636 1123314.AUIO01000002_gene1898 1.66e-138 391.0 COG5340@1|root,COG5340@2|Bacteria,1V8GF@1239|Firmicutes,4IQTV@91061|Bacilli 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin abiGI - - - - - - - - - - - AbiEi_4 OGLMJJLJ_00637 1123315.AUIP01000021_gene2249 2.21e-192 535.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii OGLMJJLJ_00638 1154860.SAG0136_09880 0.0 1756.0 COG3942@1|root,COG3942@2|Bacteria,1VPFZ@1239|Firmicutes,4HFGV@91061|Bacilli 91061|Bacilli M CHAP domain protein XK27_00530 - - - - - - - - - - - CHAP,Peptidase_M23 OGLMJJLJ_00639 996306.SSUR61_1147 0.0 1515.0 COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,4HUB9@91061|Bacilli,1WSV1@1307|Streptococcus suis 91061|Bacilli U 'COG3451 Type IV secretory pathway, VirB4 components' XK27_00545 - - - - - - - - - - - AAA_10 OGLMJJLJ_00640 1214217.ALNF01000064_gene2075 1.29e-81 241.0 2AMBF@1|root,31C6I@2|Bacteria,1U92M@1239|Firmicutes,4IJ34@91061|Bacilli,1WTK7@1307|Streptococcus suis 91061|Bacilli S PrgI family protein XK27_00550 - - - - - - - - - - - PrgI OGLMJJLJ_00641 910313.HMPREF9320_1729 2.92e-178 499.0 2EFFF@1|root,33986@2|Bacteria,1VY42@1239|Firmicutes,4HMPN@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - TrbL OGLMJJLJ_00642 1214166.ALLG01000025_gene1233 2.1e-45 147.0 295KB@1|root,2ZSXU@2|Bacteria,1W4XR@1239|Firmicutes,4I17I@91061|Bacilli,1WTPF@1307|Streptococcus suis 91061|Bacilli - - XK27_00560 - - - - - - - - - - - - OGLMJJLJ_00643 391295.SSU05_0973 0.0 1192.0 COG3505@1|root,COG3505@2|Bacteria,1UAJF@1239|Firmicutes,4IPX4@91061|Bacilli,1WT6H@1307|Streptococcus suis 91061|Bacilli U Type IV secretory system Conjugative DNA transfer XK27_00565 - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf OGLMJJLJ_00644 1214166.ALLG01000025_gene1235 1.92e-105 305.0 29QYR@1|root,30BZR@2|Bacteria,1U8XR@1239|Firmicutes,4IIWI@91061|Bacilli,1WSKJ@1307|Streptococcus suis 91061|Bacilli - - XK27_00570 - - - - - - - - - - - - OGLMJJLJ_00645 996306.SSUR61_1153 2.69e-118 340.0 COG1266@1|root,COG1266@2|Bacteria,1W5XP@1239|Firmicutes,4I0RW@91061|Bacilli,1WSW7@1307|Streptococcus suis 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi OGLMJJLJ_00646 996306.SSUR61_1154 9.04e-50 157.0 2AMF1@1|root,31CAH@2|Bacteria,1U945@1239|Firmicutes,4IJ54@91061|Bacilli,1WTQF@1307|Streptococcus suis 91061|Bacilli - - XK27_00580 - - - - - - - - - - - - OGLMJJLJ_00647 1214166.ALLG01000025_gene1238 2.57e-84 249.0 COG1393@1|root,30C2H@2|Bacteria,1U91V@1239|Firmicutes,4IJ24@91061|Bacilli,1WTGJ@1307|Streptococcus suis 91061|Bacilli P arsenate reductase (glutaredoxin) activity XK27_00585 - - - - - - - - - - - - OGLMJJLJ_00648 1214166.ALLG01000025_gene1239 5.64e-97 282.0 2EV5A@1|root,33NK4@2|Bacteria,1W4PT@1239|Firmicutes,4IJ1G@91061|Bacilli,1WTD4@1307|Streptococcus suis 91061|Bacilli - - XK27_00590 - - - - - - - - - - - - OGLMJJLJ_00649 1154860.SAG0136_10340 0.0 894.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HB9C@91061|Bacilli 91061|Bacilli H cytosine-specific methyltransferase hpaIIM - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase OGLMJJLJ_00650 1214217.ALNF01000064_gene2086 1.44e-188 524.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,1WSPT@1307|Streptococcus suis 91061|Bacilli S Replication initiator protein A (RepA) N-terminus repA - - - - - - - - - - - RepA_N OGLMJJLJ_00651 996306.SSUR61_1159 1.33e-28 102.0 2AMGJ@1|root,31CC5@2|Bacteria,1U94R@1239|Firmicutes,4IJ5U@91061|Bacilli,1WTRT@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00652 264199.stu0136 4.05e-26 99.4 COG0494@1|root,COG0494@2|Bacteria,1V8D5@1239|Firmicutes,4HJKW@91061|Bacilli 91061|Bacilli L NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX OGLMJJLJ_00653 264199.stu0135 5.89e-108 311.0 2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3013) XK27_03960 - - - - - - - - - - - DUF3013 OGLMJJLJ_00654 264199.stu0134 0.0 1063.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase OGLMJJLJ_00655 322159.STER_0192 2.92e-116 335.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH OGLMJJLJ_00656 322159.STER_0191 6.47e-286 783.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N OGLMJJLJ_00657 264199.stu0131 9.32e-189 525.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel OGLMJJLJ_00658 1046629.Ssal_02044 7.24e-102 296.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 OGLMJJLJ_00659 322159.STER_0151 1.58e-275 756.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00662 1046629.Ssal_02049 2.77e-95 279.0 COG4720@1|root,COG4720@2|Bacteria,1VBBN@1239|Firmicutes,4HNM0@91061|Bacilli 91061|Bacilli S cog cog4720 hmpT - - - - - - - - - - - ECF-ribofla_trS OGLMJJLJ_00663 264199.stu0123 1.74e-175 489.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4H9PP@91061|Bacilli 91061|Bacilli H phosphomethylpyrimidine kinase thiD - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin OGLMJJLJ_00664 264199.stu0122 1.19e-175 489.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 OGLMJJLJ_00665 322159.STER_0164 1.19e-258 710.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG OGLMJJLJ_00666 322159.STER_0163 0.0 1068.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 OGLMJJLJ_00667 264199.stu0119 3.85e-97 286.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE OGLMJJLJ_00668 264199.stu0118 2.19e-250 688.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg OGLMJJLJ_00669 264199.stu0117 3.46e-130 370.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity acmA - 3.2.1.17 ko:K01185,ko:K02395 - - - - ko00000,ko01000,ko02035 - - - Glucosaminidase OGLMJJLJ_00670 264199.stu0116 4.58e-177 494.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.16.4,3.4.17.14 ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY OGLMJJLJ_00671 322159.STER_0158 7.12e-165 461.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HJ9X@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase gpmB - - ko:K15640 - - - - ko00000 - - - His_Phos_1 OGLMJJLJ_00672 264199.stu0113 2.77e-308 842.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 OGLMJJLJ_00673 264199.stu0112 1.02e-51 163.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli 91061|Bacilli T UPF0237 protein XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 OGLMJJLJ_00674 904306.HMPREF9192_0491 2.16e-282 773.0 COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HBC3@91061|Bacilli 91061|Bacilli M Bacterial capsule synthesis protein capA - - ko:K07282 - - - - ko00000 - - - PGA_cap OGLMJJLJ_00675 1545701.LACWKB10_1399 1.32e-19 80.1 2BA4E@1|root,323IA@2|Bacteria,1U8A1@1239|Firmicutes,4II7Z@91061|Bacilli,3FARB@33958|Lactobacillaceae 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00676 1545701.LACWKB10_1400 5.47e-99 293.0 29Q8I@1|root,30B7J@2|Bacteria,1U7PC@1239|Firmicutes,4IHKP@91061|Bacilli,3F9Z8@33958|Lactobacillaceae 91061|Bacilli S ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_5 OGLMJJLJ_00677 469609.HMPREF0847_00380 1.02e-199 553.0 COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,4HUQD@91061|Bacilli 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - ABC_tran OGLMJJLJ_00681 469609.HMPREF0847_00377 2.63e-121 351.0 COG1396@1|root,COG1396@2|Bacteria,1VBRX@1239|Firmicutes,4HMPG@91061|Bacilli 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family mutR - - - - - - - - - - - HTH_19,HTH_3 OGLMJJLJ_00682 469609.HMPREF0847_00377 2.6e-48 161.0 COG1396@1|root,COG1396@2|Bacteria,1VBRX@1239|Firmicutes,4HMPG@91061|Bacilli 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family mutR - - - - - - - - - - - HTH_19,HTH_3 OGLMJJLJ_00683 469609.HMPREF0847_00376 5.15e-130 369.0 COG1396@1|root,COG1396@2|Bacteria,1VKX5@1239|Firmicutes 1239|Firmicutes K DNA-binding helix-turn-helix protein cro - - - - - - - - - - - HTH_19,HTH_3 OGLMJJLJ_00685 585204.SMSK597_1428 1.29e-48 159.0 2DKDH@1|root,3097S@2|Bacteria,1U4K6@1239|Firmicutes,4IEBY@91061|Bacilli,2TQ0T@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00686 469609.HMPREF0847_00373 1.68e-254 697.0 COG2946@1|root,COG2946@2|Bacteria,1V0X4@1239|Firmicutes,4HF5X@91061|Bacilli 91061|Bacilli L Replication initiation factor - - - - - - - - - - - - Rep_trans OGLMJJLJ_00687 469609.HMPREF0847_00372 5.52e-55 171.0 2DS5K@1|root,33ENA@2|Bacteria,1VQRI@1239|Firmicutes,4HSSZ@91061|Bacilli 91061|Bacilli S Helix-turn-helix domain - - - - - - - - - - - - HTH_17 OGLMJJLJ_00688 469609.HMPREF0847_00371 6.45e-284 776.0 COG0582@1|root,COG0582@2|Bacteria,1TRCD@1239|Firmicutes,4HDUS@91061|Bacilli 91061|Bacilli L Belongs to the 'phage' integrase family int2 - - - - - - - - - - - Phage_integrase OGLMJJLJ_00689 264199.stu0094 6.08e-84 248.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 OGLMJJLJ_00690 1046629.Ssal_02077 7.02e-103 297.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 OGLMJJLJ_00691 264199.stu0092 8.68e-229 630.0 COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,4HB4T@91061|Bacilli 91061|Bacilli H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid ykpB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA,ApbA_C OGLMJJLJ_00692 411460.RUMTOR_00063 4.48e-43 149.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,24UEE@186801|Clostridia 186801|Clostridia K helix-turn-helix - - - - - - - - - - - - HTH_3 OGLMJJLJ_00693 1216932.CM240_2784 1.29e-05 46.2 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,25F54@186801|Clostridia 186801|Clostridia K PFAM helix-turn-helix domain protein - - - - - - - - - - - - HTH_3 OGLMJJLJ_00694 264199.stu0090 2.23e-199 553.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli 91061|Bacilli S DegV family yitS - - - - - - - - - - - DegV OGLMJJLJ_00695 264199.stu0089 6.97e-121 345.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli 91061|Bacilli S RNA-binding protein containing a PIN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP OGLMJJLJ_00696 264199.stu0088 4.11e-171 478.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind OGLMJJLJ_00699 264199.stu0085 7.04e-89 261.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 OGLMJJLJ_00700 264199.stu0084 0.0 900.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g OGLMJJLJ_00701 264199.stu0083 7.75e-145 408.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli 91061|Bacilli E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep OGLMJJLJ_00702 322159.STER_0115 1.83e-183 510.0 2F67I@1|root,33YRI@2|Bacteria,1VY65@1239|Firmicutes,4HXHY@91061|Bacilli 91061|Bacilli S SseB protein N-terminal domain - - - - - - - - - - - - SseB OGLMJJLJ_00703 264199.stu0081 0.0 1384.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 OGLMJJLJ_00704 322159.STER_0113 1.62e-294 804.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 OGLMJJLJ_00705 904306.HMPREF9192_0524 1.18e-73 233.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 OGLMJJLJ_00706 264199.stu0078 3.83e-165 466.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 OGLMJJLJ_00707 264199.stu0077 0.0 1555.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR OGLMJJLJ_00708 264199.stu0076 2.83e-99 288.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR OGLMJJLJ_00709 322159.STER_0107 8.37e-108 310.0 COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,4HPN6@91061|Bacilli 91061|Bacilli S Putative small multi-drug export protein - - - - - - - - - - - - Sm_multidrug_ex OGLMJJLJ_00710 264199.stu0074 2.46e-232 641.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS OGLMJJLJ_00711 264199.stu0073 1.01e-175 490.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 OGLMJJLJ_00713 1116231.SMA_2094 1.17e-221 612.0 COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HB1P@91061|Bacilli 91061|Bacilli V proteins, homologs of microcin C7 resistance protein MccF yocD - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 OGLMJJLJ_00715 322159.STER_0101 7.42e-44 145.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_00716 264199.stu0066 2.29e-125 357.0 COG0431@1|root,COG0431@2|Bacteria,1VAI8@1239|Firmicutes 1239|Firmicutes S reductase XK27_03570 - - ko:K19784 - - - - ko00000 - - - FMN_red OGLMJJLJ_00717 264199.stu0065 2.91e-72 217.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity badR - - ko:K15973 - - - - ko00000,ko03000 - - - MarR OGLMJJLJ_00718 264199.stu0064 1.99e-48 154.0 COG2261@1|root,COG2261@2|Bacteria 2|Bacteria S Transglycosylase associated protein XK27_02060 - - - - - - - - - - - Transgly_assoc OGLMJJLJ_00719 264199.stu0063 4e-298 813.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 OGLMJJLJ_00720 322159.STER_0095 0.0 2895.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon OGLMJJLJ_00734 264199.stu0061 1.27e-86 255.0 COG1393@1|root,COG1393@2|Bacteria,1VYBB@1239|Firmicutes,4HWYC@91061|Bacilli 91061|Bacilli P Belongs to the ArsC family spxA_2 - 1.20.4.1 ko:K00537,ko:K16509 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin OGLMJJLJ_00735 322159.STER_0077 2.51e-261 717.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA OGLMJJLJ_00736 322159.STER_0076 1.89e-292 800.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth OGLMJJLJ_00737 322159.STER_0075 3.67e-136 384.0 COG2818@1|root,COG2818@2|Bacteria,1V9B8@1239|Firmicutes,4HJ4I@91061|Bacilli 91061|Bacilli L 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco OGLMJJLJ_00738 322159.STER_0074 1.78e-133 379.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N OGLMJJLJ_00740 322159.STER_0072 0.0 1254.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C OGLMJJLJ_00742 904306.HMPREF9192_0027 6.01e-89 262.0 COG3279@1|root,COG3279@2|Bacteria,1VE2H@1239|Firmicutes,4IPMG@91061|Bacilli 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR OGLMJJLJ_00743 1046629.Ssal_02119 7.24e-102 295.0 2E0UI@1|root,32WBZ@2|Bacteria,1VHBQ@1239|Firmicutes,4HRYH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 OGLMJJLJ_00744 322159.STER_0068 0.0 1625.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V OGLMJJLJ_00745 264199.stu0049 1.28e-73 221.0 COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family ymcA - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - Com_YlbF OGLMJJLJ_00746 264199.stu0048 1.36e-90 266.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli 91061|Bacilli K Regulates arginine biosynthesis genes argR - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C OGLMJJLJ_00747 523794.Lebu_0405 1.19e-67 214.0 2E4MT@1|root,32ZGR@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF3800 OGLMJJLJ_00752 322159.STER_0819 0.0 1015.0 COG3378@1|root,COG3378@2|Bacteria,1UYRX@1239|Firmicutes,4HC06@91061|Bacilli 91061|Bacilli S DNA primase - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1 OGLMJJLJ_00753 322159.STER_0820 2.23e-199 553.0 COG3378@1|root,COG3378@2|Bacteria 2|Bacteria KL Phage plasmid primase P4 family - - - ko:K06919 - - - - ko00000 - - - D5_N,Pox_D5,PriCT_1,Prim-Pol OGLMJJLJ_00754 768726.HMPREF9178_1171 2.69e-30 109.0 29UGX@1|root,30FTY@2|Bacteria,1UEN1@1239|Firmicutes,4IE9Y@91061|Bacilli,2TPXS@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00759 904306.HMPREF9192_0303 3.54e-24 92.0 COG1476@1|root,COG1476@2|Bacteria,1VK99@1239|Firmicutes,4HR9G@91061|Bacilli 91061|Bacilli K TRANSCRIPTIONal - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 OGLMJJLJ_00760 904306.HMPREF9192_0302 1.8e-48 163.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4ISM2@91061|Bacilli 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_3 OGLMJJLJ_00761 322159.STER_0829 1.18e-275 754.0 COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase OGLMJJLJ_00762 322159.STER_0065 0.0 1102.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli 91061|Bacilli J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d OGLMJJLJ_00763 264199.stu0045 1.5e-314 856.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 OGLMJJLJ_00764 585203.SMSK564_1384 6.01e-45 145.0 2DZH9@1|root,32VAR@2|Bacteria,1VIUY@1239|Firmicutes,4HZSZ@91061|Bacilli,2TPYM@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00765 264199.stu0043 4.85e-181 503.0 COG1893@1|root,COG1893@2|Bacteria,1UD8U@1239|Firmicutes 1239|Firmicutes H Ketopantoate reductase - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA OGLMJJLJ_00766 264199.stu0042 1.7e-260 714.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp OGLMJJLJ_00767 322159.STER_0059 2.66e-99 289.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC OGLMJJLJ_00768 264199.stu0040 4.06e-306 834.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N OGLMJJLJ_00769 264199.stu0039 1.71e-204 565.0 COG3942@1|root,COG3942@2|Bacteria,1VUNU@1239|Firmicutes,4HVY0@91061|Bacilli 91061|Bacilli S CHAP domain - - - - - - - - - - - - CHAP,SH3_5 OGLMJJLJ_00770 264199.stu0207 2.32e-43 141.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_00771 264199.stu0206 5.07e-41 138.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_00772 322159.STER_0055 1.28e-100 293.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_28,HTH_Tnp_1,rve OGLMJJLJ_00773 264199.stu0035 0.0 1007.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS OGLMJJLJ_00774 264199.stu0034 3.96e-131 372.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N OGLMJJLJ_00775 904306.HMPREF9192_0010 1.07e-240 662.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C OGLMJJLJ_00776 435842.HMPREF0848_01956 0.0 942.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran OGLMJJLJ_00777 264199.stu0031 0.0 2409.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 OGLMJJLJ_00778 264199.stu0030 4.31e-167 467.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt OGLMJJLJ_00779 322159.STER_0048 1.93e-46 149.0 COG0236@1|root,COG0236@2|Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP_1 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding OGLMJJLJ_00780 322159.STER_0047 6.34e-230 634.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis OGLMJJLJ_00781 322159.STER_0046 1.69e-184 513.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N OGLMJJLJ_00782 264199.stu0026 2.48e-277 759.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli 91061|Bacilli E Aminotransferase araT - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 OGLMJJLJ_00783 264199.stu0025 4.38e-35 120.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00784 264199.stu0023 4.76e-224 618.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N OGLMJJLJ_00785 322159.STER_0042 4.04e-179 516.0 COG3883@1|root,COG3942@1|root,COG3883@2|Bacteria,COG3942@2|Bacteria,1VCXB@1239|Firmicutes,4IS6H@91061|Bacilli 91061|Bacilli S CHAP domain pcsB - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP OGLMJJLJ_00786 322159.STER_0041 1.34e-115 332.0 COG2891@1|root,COG2891@2|Bacteria 2|Bacteria M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins mreD GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD OGLMJJLJ_00787 322159.STER_0040 9.56e-180 502.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC OGLMJJLJ_00806 888048.HMPREF8577_0808 2.4e-131 377.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_00807 322159.STER_0016 2.56e-24 97.4 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - HTH_Tnp_1 OGLMJJLJ_00808 322159.STER_1757 2.5e-57 178.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_Tnp_1 OGLMJJLJ_00809 322159.STER_0015 1.3e-209 580.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00810 322159.STER_0014 0.0 1255.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 OGLMJJLJ_00811 264199.stu0011 2.22e-126 359.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 - - - Pribosyltran OGLMJJLJ_00812 264199.stu0010 2.54e-305 832.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli 91061|Bacilli D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C OGLMJJLJ_00813 322159.STER_0011 8.89e-306 834.0 COG2367@1|root,COG2367@2|Bacteria,1VGXR@1239|Firmicutes,4IPWW@91061|Bacilli 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase2,SH3_8 OGLMJJLJ_00814 388919.SSA_0011 1.94e-05 43.5 29RP0@1|root,30CSA@2|Bacteria,1UAAD@1239|Firmicutes,4IKMY@91061|Bacilli,1WS12@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00815 322159.STER_0009 1.16e-80 239.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC OGLMJJLJ_00816 264199.stu0007 3.77e-53 167.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli 91061|Bacilli J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) yabO - - - - - - - - - - - S4 OGLMJJLJ_00817 322159.STER_0007 0.0 2252.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF OGLMJJLJ_00818 264199.stu0005 4.43e-135 382.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro OGLMJJLJ_00819 264199.stu0004 1.06e-258 710.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C OGLMJJLJ_00820 1046629.Ssal_02164 8.11e-40 131.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria yyzM - - - - - - - - - - - DUF951 OGLMJJLJ_00821 322159.STER_0002 1.57e-259 712.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 OGLMJJLJ_00822 264199.stu0001 0.0 892.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N OGLMJJLJ_00823 322159.STER_2003 6.53e-172 481.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc OGLMJJLJ_00824 264199.stu2024 1.78e-268 738.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli 91061|Bacilli O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain' htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 OGLMJJLJ_00825 904306.HMPREF9192_1865 5.98e-111 319.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase OGLMJJLJ_00826 264199.stu2022 8.63e-154 432.0 COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes 1239|Firmicutes S Psort location CytoplasmicMembrane, score yveI - - - - - - - - - - - DUF1275 OGLMJJLJ_00830 264199.stu2021 0.0 1655.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli 91061|Bacilli S Bacterial membrane protein YfhO XK27_10405 - - - - - - - - - - - YfhO OGLMJJLJ_00831 264199.stu2020 0.0 1051.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn OGLMJJLJ_00832 322159.STER_1994 5.01e-158 446.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli 91061|Bacilli S membrane XK27_10395 - - - - - - - - - - - DUF2179,YitT_membrane OGLMJJLJ_00833 264199.stu2018 1.17e-244 672.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli 91061|Bacilli J Tryptophanyl-tRNA synthetase trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b OGLMJJLJ_00834 322159.STER_1992 0.0 947.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH OGLMJJLJ_00835 322159.STER_1991 5.28e-261 715.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N OGLMJJLJ_00836 264199.stu2014 3.04e-68 208.0 COG2501@1|root,COG2501@2|Bacteria,1VKF4@1239|Firmicutes,4HRX5@91061|Bacilli 91061|Bacilli S S4 domain protein YaaA yaaA - - - - - - - - - - - S4_2 OGLMJJLJ_00837 322159.STER_1989 1.76e-298 814.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C OGLMJJLJ_00838 264199.stu2012 1.21e-303 828.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C OGLMJJLJ_00839 322159.STER_1987 1.2e-182 510.0 COG1426@1|root,COG1426@2|Bacteria 2|Bacteria S sequence-specific DNA binding ymfM - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25 OGLMJJLJ_00840 264199.stu2010 7.67e-118 338.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf OGLMJJLJ_00841 322159.STER_1985 1.83e-193 537.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran OGLMJJLJ_00842 264199.stu2008 1.75e-193 537.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran OGLMJJLJ_00843 264199.stu2007 4.75e-174 487.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ OGLMJJLJ_00844 264199.stu2006 4.41e-119 341.0 COG1388@1|root,COG1388@2|Bacteria,1VA10@1239|Firmicutes,4HMUH@91061|Bacilli 91061|Bacilli M LysM domain protein lytE - - - - - - - - - - - LysM OGLMJJLJ_00845 322159.STER_1981 3.54e-119 343.0 COG0741@1|root,COG0741@2|Bacteria,1VGPA@1239|Firmicutes,4HP1I@91061|Bacilli 91061|Bacilli M Immunodominant staphylococcal antigen A isaA - - - - - - - - - - - DUF348,G5,LysM,SLT,Transglycosylas OGLMJJLJ_00846 322159.STER_1980 0.0 1036.0 COG4485@1|root,COG4485@2|Bacteria,1V0XZ@1239|Firmicutes,4HEBN@91061|Bacilli 91061|Bacilli S Bacterial membrane protein, YfhO - - - - - - - - - - - - - OGLMJJLJ_00847 1046629.Ssal_00023 3.93e-271 741.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans OGLMJJLJ_00848 435842.HMPREF0848_01708 2.83e-99 288.0 COG1051@1|root,COG1051@2|Bacteria,1VAVP@1239|Firmicutes,4HSPC@91061|Bacilli 91061|Bacilli F NUDIX domain - - - - - - - - - - - - NUDIX OGLMJJLJ_00849 435842.HMPREF0848_01709 0.0 1219.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc OGLMJJLJ_00850 322159.STER_1977 0.0 1251.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 OGLMJJLJ_00851 322159.STER_1976 3.57e-98 286.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli 91061|Bacilli J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N OGLMJJLJ_00852 322159.STER_1975 1.29e-312 853.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaC GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C OGLMJJLJ_00853 264199.stu1998 3.05e-63 193.0 COG4466@1|root,COG4466@2|Bacteria,1VPZY@1239|Firmicutes,4HSFF@91061|Bacilli 91061|Bacilli S Biofilm formation stimulator VEG WQ51_01655 - - - - - - - - - - - VEG OGLMJJLJ_00854 264199.stu1997 1.39e-139 395.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 OGLMJJLJ_00855 1123318.KB904633_gene1270 4.05e-11 59.3 2914P@1|root,2ZNS1@2|Bacteria,1W3FT@1239|Firmicutes,4I23Q@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00856 1046629.Ssal_00032 1.19e-15 71.2 COG3759@1|root,COG3759@2|Bacteria,1VAEU@1239|Firmicutes 1239|Firmicutes M Membrane XK27_04840 - - ko:K08987 - - - - ko00000 - - - DUF1304 OGLMJJLJ_00857 264199.stu1995 5.43e-122 348.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator XK27_06935 - - - - - - - - - - - TetR_C_8,TetR_N OGLMJJLJ_00858 322159.STER_1969 1.87e-249 720.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli 91061|Bacilli V domain protein XK27_06930 - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 OGLMJJLJ_00859 264199.stu1992 5.5e-145 416.0 COG3595@1|root,COG3595@2|Bacteria,1VGGF@1239|Firmicutes,4I0VY@91061|Bacilli 91061|Bacilli S Putative adhesin - - - - - - - - - - - - DUF4097 OGLMJJLJ_00860 904306.HMPREF9192_1905 1.42e-19 85.1 COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,4HSRQ@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1700) - - - - - - - - - - - - DUF1700 OGLMJJLJ_00861 435842.HMPREF0848_01720 9.72e-11 59.7 COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,4HSRQ@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1700) - - - - - - - - - - - - DUF1700 OGLMJJLJ_00862 435842.HMPREF0848_01721 1.34e-63 195.0 COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,4IR4R@91061|Bacilli 91061|Bacilli K transcriptional regulator, PadR family XK27_06915 - - ko:K10947 - - - - ko00000,ko03000 - - - PadR OGLMJJLJ_00863 322159.STER_0367 1.77e-283 774.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_00864 1046629.Ssal_00038 1.58e-139 394.0 COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli 91061|Bacilli L hydrolase XK27_06885 - - - - - - - - - - - NUDIX OGLMJJLJ_00865 264199.stu1987 1.01e-26 99.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like - - - - - - - - - - - - CsbD OGLMJJLJ_00866 264199.stu1986 1.03e-113 328.0 COG1302@1|root,COG1302@2|Bacteria 2|Bacteria M Protein conserved in bacteria - - - - - - - - - - - - Asp23 OGLMJJLJ_00867 264199.stu1984 7.53e-33 113.0 COG5547@1|root,COG5547@2|Bacteria 2|Bacteria S Small integral membrane protein - - - - - - - - - - - - DUF2273 OGLMJJLJ_00868 322159.STER_1960 5.17e-129 367.0 2ED8H@1|root,33752@2|Bacteria,1VK2R@1239|Firmicutes,4HQ99@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00869 322159.STER_1959 7.98e-45 145.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli 91061|Bacilli S Membrane ytgB - - - - - - - - - - - Transgly_assoc OGLMJJLJ_00871 264199.stu1980 6.93e-123 352.0 COG1808@1|root,COG1808@2|Bacteria,1TRFZ@1239|Firmicutes 1239|Firmicutes S Hydrophobic domain protein - - - - - - - - - - - - DUF389 OGLMJJLJ_00872 1069533.Sinf_1920 1.27e-19 85.9 COG1597@1|root,COG1597@2|Bacteria,1TQ9A@1239|Firmicutes 1239|Firmicutes I Diacylglycerol kinase yegS - - - - - - - - - - - DAGK_cat OGLMJJLJ_00873 1069533.Sinf_1920 2.77e-146 417.0 COG1597@1|root,COG1597@2|Bacteria,1TQ9A@1239|Firmicutes 1239|Firmicutes I Diacylglycerol kinase yegS - - - - - - - - - - - DAGK_cat OGLMJJLJ_00876 1046629.Ssal_00051 1.22e-26 97.4 COG0267@1|root,COG0267@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 OGLMJJLJ_00877 1123315.AUIP01000010_gene919 4.33e-36 122.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p OGLMJJLJ_00878 1046629.Ssal_00053 2.66e-44 152.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 OGLMJJLJ_00879 1046629.Ssal_00053 4.02e-80 246.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 OGLMJJLJ_00880 1046629.Ssal_00053 6.96e-65 207.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 OGLMJJLJ_00881 322159.STER_1950 6.78e-308 839.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His OGLMJJLJ_00883 322159.STER_1948 0.0 1136.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon OGLMJJLJ_00884 322159.STER_1947 1.53e-215 596.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli 91061|Bacilli S cog cog1284 XK27_01785 - - - - - - - - - - - DUF2179,YitT_membrane OGLMJJLJ_00885 322159.STER_1946 9.78e-189 524.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD OGLMJJLJ_00886 322159.STER_1945 1.26e-149 420.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM OGLMJJLJ_00887 322159.STER_1944 1.31e-118 338.0 COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 OGLMJJLJ_00888 435842.HMPREF0848_01736 7.68e-20 80.1 2DEKJ@1|root,2ZNBP@2|Bacteria,1TXD1@1239|Firmicutes,4HZYT@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00889 322159.STER_1942 0.0 1492.0 COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD OGLMJJLJ_00890 264199.stu1962 0.0 1030.0 2F2IJ@1|root,33VFI@2|Bacteria,1V9D8@1239|Firmicutes,4HS77@91061|Bacilli 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - - OGLMJJLJ_00891 322159.STER_1939 2.7e-62 191.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 OGLMJJLJ_00892 264199.stu1960 1.7e-92 270.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX OGLMJJLJ_00893 264199.stu1959 3.98e-58 179.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 OGLMJJLJ_00894 264199.stu1958 4.09e-35 119.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 OGLMJJLJ_00895 264199.stu1957 1.07e-302 825.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli 91061|Bacilli L ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N OGLMJJLJ_00897 264199.stu1955 1.75e-277 758.0 COG0582@1|root,COG0582@2|Bacteria,1VTS1@1239|Firmicutes,4HU1E@91061|Bacilli 91061|Bacilli L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase OGLMJJLJ_00898 585204.SMSK597_1426 1.95e-26 97.8 28YJG@1|root,2ZKDA@2|Bacteria,1W5B5@1239|Firmicutes,4I02K@91061|Bacilli,2TQ3X@28037|Streptococcus mitis 91061|Bacilli S Domain of unknown function (DUF3173) - - - - - - - - - - - - DUF3173 OGLMJJLJ_00899 1403946.Q615_SPAC00126G0051 1.04e-205 572.0 COG2946@1|root,COG2946@2|Bacteria,1VMP1@1239|Firmicutes,4HSQH@91061|Bacilli,42EH0@671232|Streptococcus anginosus group 91061|Bacilli L Replication initiation factor - - - - - - - - - - - - Rep_trans OGLMJJLJ_00900 322159.STER_1926 1.71e-116 333.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 OGLMJJLJ_00901 264199.stu1952 0.0 988.0 COG1132@1|root,COG1132@2|Bacteria,1VRZB@1239|Firmicutes,4HV44@91061|Bacilli 91061|Bacilli V ABC transporter transmembrane region - - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran OGLMJJLJ_00902 264199.stu1951 1.15e-296 809.0 COG0641@1|root,COG0641@2|Bacteria,1V5NX@1239|Firmicutes 1239|Firmicutes C Radical SAM - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM,SPASM OGLMJJLJ_00904 264199.stu1950 1.17e-163 460.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding Z012_04635 - - - - - - - - - - - HTH_3,HTH_31 OGLMJJLJ_00905 927666.SOR_0524 2.93e-40 133.0 2DJ35@1|root,304P3@2|Bacteria,1TWZ1@1239|Firmicutes,4I5TZ@91061|Bacilli,1WPY9@1303|Streptococcus oralis 91061|Bacilli S Domain of unknown function (DUF4649) - - - - - - - - - - - - DUF4649 OGLMJJLJ_00906 764298.STRMA_0446 3.04e-164 462.0 COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli 91061|Bacilli IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) gdh - 1.1.1.47 ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 - R01520,R01521 RC00066 ko00000,ko00001,ko01000 - - iYO844.BSU03930 adh_short_C2 OGLMJJLJ_00907 904306.HMPREF9192_1949 1.8e-64 199.0 COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli 91061|Bacilli F topology modulation protein flaR - - - - - - - - - - - - OGLMJJLJ_00908 322159.STER_0367 5.1e-264 724.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_00909 1116231.SMA_1918 1.33e-251 690.0 COG0476@1|root,COG0476@2|Bacteria 2|Bacteria H Involved in molybdopterin and thiamine biosynthesis, family 2 - - 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF OGLMJJLJ_00910 1116231.SMA_1917 9.85e-248 684.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily yxaM - - - - - - - - - - - MFS_1 OGLMJJLJ_00911 1046629.Ssal_00076 1.25e-115 331.0 COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli 91061|Bacilli F topology modulation protein flaR - - - - - - - - - - - - OGLMJJLJ_00912 322159.STER_1913 7.73e-316 859.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt OGLMJJLJ_00913 322159.STER_0151 8.76e-186 523.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00914 1046629.Ssal_00039 1.41e-88 270.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00915 264199.stu1939 9.32e-106 304.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc OGLMJJLJ_00916 264199.stu1938 2.43e-47 156.0 COG4642@1|root,COG4642@2|Bacteria,1TRNW@1239|Firmicutes 1239|Firmicutes S MORN repeat protein - - - - - - - - - - - - MORN OGLMJJLJ_00917 264199.stu1937 0.0 1159.0 COG1835@1|root,COG1835@2|Bacteria,1U6DU@1239|Firmicutes,4H9XT@91061|Bacilli 91061|Bacilli I Acyltransferase XK27_09800 - - - - - - - - - - - Acyl_transf_3 OGLMJJLJ_00918 264199.stu1936 4.19e-239 657.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N OGLMJJLJ_00919 1046629.Ssal_00083 4.29e-64 196.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 OGLMJJLJ_00920 264199.stu1934 2.23e-142 402.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 OGLMJJLJ_00921 1046629.Ssal_00085 4.3e-135 384.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 OGLMJJLJ_00922 264199.stu1932 6e-60 185.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 OGLMJJLJ_00923 264199.stu1931 4.16e-195 541.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C OGLMJJLJ_00924 322159.STER_1903 1.99e-62 191.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 OGLMJJLJ_00925 1046629.Ssal_00089 1.21e-71 216.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 OGLMJJLJ_00926 264199.stu1928 2.49e-148 418.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C OGLMJJLJ_00927 322159.STER_1900 1.2e-91 268.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 OGLMJJLJ_00928 264199.stu1926 4.36e-35 120.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 OGLMJJLJ_00929 1046629.Ssal_00093 3.08e-52 164.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 OGLMJJLJ_00930 264199.stu1924 1.04e-78 234.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 OGLMJJLJ_00931 264199.stu1923 1.98e-64 196.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 OGLMJJLJ_00932 264199.stu1922 5.86e-122 348.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C OGLMJJLJ_00933 264199.stu1921 2.03e-39 130.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 OGLMJJLJ_00934 1123304.AQYA01000030_gene1163 5.37e-88 258.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 OGLMJJLJ_00935 264199.stu1919 1.44e-121 347.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 OGLMJJLJ_00936 322159.STER_1891 5.03e-75 224.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p OGLMJJLJ_00937 264199.stu1917 9.94e-104 301.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C OGLMJJLJ_00938 264199.stu1916 2e-32 112.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli 91061|Bacilli J ribosomal protein l30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 OGLMJJLJ_00939 322159.STER_1888 1.4e-83 248.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli 91061|Bacilli J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A OGLMJJLJ_00940 322159.STER_1887 1.95e-289 793.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY OGLMJJLJ_00941 264199.stu1913 2.61e-155 436.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid OGLMJJLJ_00942 1046629.Ssal_00106 1.98e-44 144.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a OGLMJJLJ_00943 1123301.KB904201_gene1724 3.26e-22 85.5 COG0257@1|root,COG0257@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 OGLMJJLJ_00944 1046629.Ssal_00108 4.42e-75 225.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 OGLMJJLJ_00945 264199.stu1909 1.57e-80 239.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 OGLMJJLJ_00946 264199.stu1908 5.37e-220 607.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L OGLMJJLJ_00947 264199.stu1907 2.13e-83 246.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli 91061|Bacilli J ribosomal protein l17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 OGLMJJLJ_00948 1046629.Ssal_00197 2.63e-91 273.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli 91061|Bacilli L PFAM Integrase, catalytic core - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve OGLMJJLJ_00949 1046629.Ssal_00544 7.69e-18 79.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli 91061|Bacilli L PFAM Integrase, catalytic core - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve OGLMJJLJ_00950 904306.HMPREF9192_1984 1.43e-15 77.0 COG3572@1|root,COG3572@2|Bacteria,1TW3D@1239|Firmicutes,4HTV4@91061|Bacilli 91061|Bacilli H gamma-glutamylcysteine synthetase - - - - - - - - - - - - GCS2 OGLMJJLJ_00951 1046629.Ssal_00112 1.44e-41 147.0 COG3572@1|root,COG3572@2|Bacteria,1TW3D@1239|Firmicutes,4HTV4@91061|Bacilli 91061|Bacilli H gamma-glutamylcysteine synthetase - - - - - - - - - - - - GCS2 OGLMJJLJ_00952 264199.stu1900 8.74e-134 380.0 COG3572@1|root,COG3572@2|Bacteria 2|Bacteria H ergothioneine biosynthetic process - - 6.3.2.2 ko:K01919,ko:K06048 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 OGLMJJLJ_00954 322159.STER_1876 1.21e-211 584.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli 91061|Bacilli G aldolase fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase OGLMJJLJ_00956 322159.STER_0151 8.16e-181 510.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_00957 1214166.ALLG01000004_gene434 2.06e-261 723.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH OGLMJJLJ_00958 1214166.ALLG01000004_gene435 6.49e-61 189.0 2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HQG9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_00959 997830.HMPREF1124_1826 4.65e-58 180.0 2E660@1|root,330UP@2|Bacteria,1VFJD@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_00960 1215915.BN193_04215 4.58e-13 63.5 COG3039@1|root,COG3039@2|Bacteria,1VJ28@1239|Firmicutes,4HQR7@91061|Bacilli 2|Bacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 OGLMJJLJ_00961 1116231.SMA_0302 7.16e-21 87.4 COG3316@1|root,COG3316@2|Bacteria,1UTIC@1239|Firmicutes,4HCF1@91061|Bacilli 1239|Firmicutes L DDE domain - - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 OGLMJJLJ_00962 322159.STER_1196 1.01e-251 689.0 COG3039@1|root,COG3039@2|Bacteria,1UEG7@1239|Firmicutes 1239|Firmicutes L transposase, IS4 family - - - ko:K07481 - - - - ko00000 - - - DDE_Tnp_1,DUF772 OGLMJJLJ_00963 264199.stu0099 6.74e-40 142.0 COG4403@1|root,COG4403@2|Bacteria 2|Bacteria V Lanthionine synthetase C family protein spaC2 - - ko:K20484 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001 - - - DUF4135,LANC_like OGLMJJLJ_00964 883113.HMPREF9708_01392 9.54e-259 714.0 COG0477@1|root,COG2814@2|Bacteria,1UI3B@1239|Firmicutes,4ISBW@91061|Bacilli 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 OGLMJJLJ_00965 1069533.Sinf_0250 1.98e-51 162.0 COG2963@1|root,COG2963@2|Bacteria,1VC7D@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_00966 1069533.Sinf_0249 3.19e-197 545.0 COG2801@1|root,COG2801@2|Bacteria,1TRUP@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - - - - - - - - - - rve,rve_3 OGLMJJLJ_00967 169963.lmo1102 7.96e-62 191.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HJ09@91061|Bacilli,26M2C@186820|Listeriaceae 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 OGLMJJLJ_00968 169963.lmo1101 4e-82 246.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 OGLMJJLJ_00969 169963.lmo1100 0.0 1278.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,26JS1@186820|Listeriaceae 91061|Bacilli P E1-E2 ATPase cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase OGLMJJLJ_00970 169963.lmo1099 7.3e-70 212.0 COG1595@1|root,COG1595@2|Bacteria,1W79P@1239|Firmicutes,4I0N4@91061|Bacilli,26MZ4@186820|Listeriaceae 91061|Bacilli K Sigma-70, region 4 - - - - - - - - - - - - Sigma70_r4_2 OGLMJJLJ_00971 272563.CD630_22240 7.28e-42 137.0 2AJW5@1|root,337FZ@2|Bacteria,1VJQN@1239|Firmicutes 1239|Firmicutes S Helix-turn-helix domain - - - - - - - - - - - - HTH_16 OGLMJJLJ_00972 1121115.AXVN01000025_gene941 3.73e-40 132.0 2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,3Y0H0@572511|Blautia 186801|Clostridia S Psort location Cytoplasmic, score 8.87 - - - - - - - - - - - - Tn916-Xis OGLMJJLJ_00973 1151292.QEW_2309 4.4e-252 695.0 COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,25R4G@186804|Peptostreptococcaceae 186801|Clostridia L Belongs to the 'phage' integrase family - - - - - - - - - - - - Integrase_DNA,Phage_int_SAM_5,Phage_integrase OGLMJJLJ_00974 264199.stu1898 7.49e-95 277.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli 91061|Bacilli L PFAM Integrase, catalytic core - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve OGLMJJLJ_00975 1046629.Ssal_02110 7.34e-42 146.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli 91061|Bacilli L PFAM Integrase, catalytic core - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve OGLMJJLJ_00978 322159.STER_1865 1.87e-121 347.0 COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli 91061|Bacilli S Belongs to the UPF0340 family ywlG - - - - - - - - - - - DUF436 OGLMJJLJ_00979 264199.stu1893 6.51e-114 327.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli 91061|Bacilli K trehalose operon treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA OGLMJJLJ_00980 264199.stu1890 3.49e-72 218.0 COG1263@1|root,COG1263@2|Bacteria 2|Bacteria G PTS System treB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0015766,GO:0015771,GO:0015772,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563,GO:0090589 2.7.1.201 ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - iECABU_c1320.ECABU_c48060,ic_1306.c5339 PTS_EIIA_1,PTS_EIIB,PTS_EIIC OGLMJJLJ_00981 1114965.Spaf_1558 3.86e-98 300.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C OGLMJJLJ_00982 264199.stu1886 2.76e-147 416.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C OGLMJJLJ_00983 322159.STER_1860 0.0 1286.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N OGLMJJLJ_00984 264199.stu1884 1.32e-83 247.0 COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,4IS6J@91061|Bacilli 91061|Bacilli C Dehydrogenase - - 1.1.1.1,1.2.1.10,1.2.1.87 ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927,R09097 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - - Aldedh OGLMJJLJ_00985 904306.HMPREF9192_1994 3.27e-191 555.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adh - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - iSB619.SA_RS00885 Aldedh,Fe-ADH OGLMJJLJ_00986 264199.stu1881 3.46e-87 257.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adh - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - iSB619.SA_RS00885 Aldedh,Fe-ADH OGLMJJLJ_00987 904306.HMPREF9192_1994 8e-47 166.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adh - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - iSB619.SA_RS00885 Aldedh,Fe-ADH OGLMJJLJ_00988 322159.STER_1857 0.0 962.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N OGLMJJLJ_00989 322159.STER_1856 3.75e-286 784.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli 91061|Bacilli V Mate efflux family protein norN - - - - - - - - - - - MatE OGLMJJLJ_00990 322159.STER_1855 1.87e-76 228.0 COG1302@1|root,COG1302@2|Bacteria,1V3Q6@1239|Firmicutes,4HHYJ@91061|Bacilli 91061|Bacilli S cog cog1302 asp - - - - - - - - - - - Asp23 OGLMJJLJ_00991 264199.stu1875 0.0 1040.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 OGLMJJLJ_00992 904306.HMPREF9192_2000 0.0 1118.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli 91061|Bacilli E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ILVD_EDD OGLMJJLJ_00993 322159.STER_1850 0.0 1098.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli 91061|Bacilli EH Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iYO844.BSU28310 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N OGLMJJLJ_00994 264199.stu1872 9.67e-99 288.0 COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli 91061|Bacilli E Acetolactate synthase ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ACT,ACT_5,ALS_ss_C OGLMJJLJ_00995 322159.STER_1848 2.67e-250 686.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli 91061|Bacilli H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN OGLMJJLJ_00996 264199.stu1870 2.04e-303 828.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b OGLMJJLJ_00997 264199.stu1869 0.0 1556.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase OGLMJJLJ_00998 322159.STER_1845 0.0 2325.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 OGLMJJLJ_00999 322159.STER_1844 0.0 2381.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 OGLMJJLJ_01000 264199.stu1866 7.64e-89 259.0 COG4699@1|root,COG4699@2|Bacteria,1VHC7@1239|Firmicutes,4HS15@91061|Bacilli 91061|Bacilli S cog cog4699 - - - - - - - - - - - - DUF1033 OGLMJJLJ_01001 322159.STER_1842 9.35e-226 622.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli 91061|Bacilli NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE OGLMJJLJ_01002 264199.stu1864 6.09e-194 542.0 COG1459@1|root,COG1459@2|Bacteria,1U00C@1239|Firmicutes,4HGUA@91061|Bacilli 91061|Bacilli NU type II secretion system comGB - - ko:K02244 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSF OGLMJJLJ_01003 322159.STER_1840 4.5e-62 191.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli 91061|Bacilli U Required for transformation and DNA binding comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl OGLMJJLJ_01004 264199.stu1862 2.43e-74 224.0 COG2165@1|root,33A38@2|Bacteria,1VPGT@1239|Firmicutes,4HRZ0@91061|Bacilli 91061|Bacilli NU Competence protein cglD - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - - OGLMJJLJ_01005 1035184.HMPREF1042_2019 1.9e-11 61.6 COG2165@1|root,32FK6@2|Bacteria,1TVQG@1239|Firmicutes,4I3V4@91061|Bacilli,42DQU@671232|Streptococcus anginosus group 91061|Bacilli NU Type II secretory pathway pseudopilin - - - - - - - - - - - - PulG OGLMJJLJ_01006 322159.STER_1837 2.66e-92 270.0 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli 91061|Bacilli U Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl OGLMJJLJ_01007 1035189.HMPREF9954_0332 1.77e-08 56.2 2DIXE@1|root,304BJ@2|Bacteria,1TWFY@1239|Firmicutes,4I599@91061|Bacilli,43G53@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01008 264199.stu1858 2.29e-224 619.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli 91061|Bacilli L DNA methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase OGLMJJLJ_01009 264199.stu1857 1.33e-281 770.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase OGLMJJLJ_01010 1046629.Ssal_00151 4.3e-36 122.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding lanR - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 OGLMJJLJ_01011 264199.stu1855 4.55e-86 255.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi OGLMJJLJ_01013 264199.stu1853 1.13e-141 401.0 COG1266@1|root,COG1266@2|Bacteria,1VEE2@1239|Firmicutes,4HP4A@91061|Bacilli 91061|Bacilli S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi OGLMJJLJ_01014 264199.stu1852 1.17e-170 478.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4HCBY@91061|Bacilli 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer OGLMJJLJ_01015 322159.STER_1827 3.7e-260 712.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 OGLMJJLJ_01017 264199.stu1849 3.48e-73 219.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin OGLMJJLJ_01018 264199.stu1848 5.51e-147 414.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind OGLMJJLJ_01019 264199.stu1847 4.93e-243 668.0 COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,4HDN0@91061|Bacilli 91061|Bacilli S Sulphur transport yeeE - - ko:K07112 - - - - ko00000 - - - Sulf_transp OGLMJJLJ_01020 264199.stu1846 2.25e-49 156.0 COG0425@1|root,COG0425@2|Bacteria 2|Bacteria O sulfur carrier activity yeeD GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - ko:K07112 - - - - ko00000 - - - Sulf_transp,TusA OGLMJJLJ_01021 322159.STER_1821 3.13e-86 254.0 COG0629@1|root,COG0629@2|Bacteria,1VXMZ@1239|Firmicutes,4HXCW@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB OGLMJJLJ_01022 322159.STER_1819 5.94e-118 337.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam OGLMJJLJ_01025 322159.STER_1816 8.48e-204 563.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 OGLMJJLJ_01026 264199.stu1841 1.79e-84 249.0 COG1011@1|root,COG1011@2|Bacteria 2|Bacteria S phosphatase activity - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase_like OGLMJJLJ_01027 264199.stu1840 5.41e-63 194.0 COG0546@1|root,COG0546@2|Bacteria 2|Bacteria S glycolate biosynthetic process - - - ko:K07025 - - - - ko00000 - - - HAD_2 OGLMJJLJ_01028 264199.stu1839 6.92e-105 309.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep OGLMJJLJ_01029 264199.stu1838 2.31e-281 768.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 OGLMJJLJ_01030 264199.stu1837 9.45e-121 345.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig OGLMJJLJ_01031 264199.stu1836 2.79e-153 431.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 OGLMJJLJ_01032 264199.stu1833 1.79e-214 592.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase OGLMJJLJ_01033 264199.stu1832 7.25e-237 653.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N OGLMJJLJ_01034 435842.HMPREF0848_01838 3.81e-39 134.0 2BY0N@1|root,321KG@2|Bacteria 2|Bacteria S Psort location CytoplasmicMembrane, score XK27_08585 - - ko:K16926 - M00582 - - ko00000,ko00002,ko02000 3.A.1.31 - - Trep_Strep OGLMJJLJ_01035 1046629.Ssal_00177 2.5e-42 143.0 2BY0N@1|root,321KG@2|Bacteria 2|Bacteria S Psort location CytoplasmicMembrane, score XK27_08585 - - ko:K16926 - M00582 - - ko00000,ko00002,ko02000 3.A.1.31 - - Trep_Strep OGLMJJLJ_01036 435842.HMPREF0848_01839 4.45e-117 339.0 COG2116@1|root,COG2116@2|Bacteria,1V164@1239|Firmicutes,4HFJC@91061|Bacilli 91061|Bacilli P Formate nitrite transporter nirC_1 - - - - - - - - - - - Form_Nir_trans OGLMJJLJ_01037 1046629.Ssal_00180 3.56e-280 768.0 COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli 91061|Bacilli C reductase XK27_09615 - - ko:K19784 - - - - ko00000 - - - FMN_red,PAS_10 OGLMJJLJ_01038 1046629.Ssal_00181 9.7e-46 151.0 COG0431@1|root,COG0431@2|Bacteria 2|Bacteria S FMN reductase (NADPH) activity XK27_09620 - - - - - - - - - - - FMN_red OGLMJJLJ_01039 264199.stu1825 1.24e-26 100.0 COG0431@1|root,COG0431@2|Bacteria 2|Bacteria S FMN reductase (NADPH) activity XK27_09620 - - - - - - - - - - - FMN_red OGLMJJLJ_01040 264199.stu1824 2.98e-104 301.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli 91061|Bacilli F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase OGLMJJLJ_01041 264199.stu1823 1.08e-287 787.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI OGLMJJLJ_01042 435842.HMPREF0848_01845 2.3e-16 75.5 COG2013@1|root,COG2013@2|Bacteria,1V6BD@1239|Firmicutes,4HIAR@91061|Bacilli 91061|Bacilli S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 OGLMJJLJ_01043 264199.stu1822 5.51e-46 148.0 COG2013@1|root,COG2013@2|Bacteria 2|Bacteria S Mitochondrial biogenesis AIM24 WQ51_05710 - - - - - - - - - - - AIM24 OGLMJJLJ_01044 904306.HMPREF9192_2050 8.03e-38 132.0 COG2013@1|root,COG2013@2|Bacteria,1V6BD@1239|Firmicutes,4HIAR@91061|Bacilli 91061|Bacilli S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 OGLMJJLJ_01045 264199.stu1820 9.62e-116 331.0 COG0288@1|root,COG0288@2|Bacteria,1V0TA@1239|Firmicutes,4HB9V@91061|Bacilli 91061|Bacilli P Reversible hydration of carbon dioxide cah - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA OGLMJJLJ_01046 264199.stu1819 1.34e-65 201.0 2DSU9@1|root,33HF9@2|Bacteria,1VNK9@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 OGLMJJLJ_01047 264199.stu1818 1.69e-93 273.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N OGLMJJLJ_01048 264199.stu1817 1.94e-155 437.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 OGLMJJLJ_01049 904306.HMPREF9192_2056 3.83e-227 640.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 OGLMJJLJ_01050 264199.stu1815 2.44e-82 245.0 COG4166@1|root,COG4166@2|Bacteria 2|Bacteria E transmembrane transport amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 OGLMJJLJ_01051 264199.stu1814 0.0 967.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c OGLMJJLJ_01052 264199.stu1813 7.52e-293 799.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth OGLMJJLJ_01053 264199.stu1812 0.0 909.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli 91061|Bacilli E Argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 OGLMJJLJ_01054 264199.stu1811 2.38e-72 217.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P OGLMJJLJ_01055 264199.stu1810 8.54e-179 501.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP OGLMJJLJ_01056 264199.stu1809 8.06e-236 650.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli 91061|Bacilli S RNA-binding protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H OGLMJJLJ_01058 264199.stu1808 9.33e-20 79.7 COG0230@1|root,COG0230@2|Bacteria 2|Bacteria J Ribosomal protein L34 rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 OGLMJJLJ_01059 264199.stu1807 1.9e-109 315.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,4HGN6@91061|Bacilli 91061|Bacilli L Transposase - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp OGLMJJLJ_01060 322159.STER_1785 2.84e-288 785.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT OGLMJJLJ_01064 322159.STER_0151 9.82e-299 815.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01065 264199.stu1805 3.38e-72 217.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis bta - 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko01000,ko03110 - - - Thioredoxin,TraF OGLMJJLJ_01066 435842.HMPREF0848_01462 1.69e-18 80.5 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli 91061|Bacilli L thioesterase yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 OGLMJJLJ_01067 264199.stu1804 5.24e-185 514.0 COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,4HCXD@91061|Bacilli 91061|Bacilli S Macro domain protein - - - - - - - - - - - - Macro OGLMJJLJ_01068 264199.stu1803 1.54e-67 204.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin OGLMJJLJ_01069 264199.stu1802 1.14e-98 286.0 COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli 91061|Bacilli S CoA-binding protein yneT - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 OGLMJJLJ_01070 264199.stu1801 2.6e-184 512.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli 91061|Bacilli L Hydrolase, tatd tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase OGLMJJLJ_01071 322159.STER_1773 1.05e-127 363.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 OGLMJJLJ_01072 264199.stu1799 1.06e-199 554.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD OGLMJJLJ_01074 264199.stu1798 1.31e-209 579.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli 91061|Bacilli G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N OGLMJJLJ_01075 264199.stu1797 1.6e-152 429.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim OGLMJJLJ_01076 264199.stu1796 2.24e-152 427.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic OGLMJJLJ_01077 264199.stu1795 3.8e-235 655.0 COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,4HE2N@91061|Bacilli 91061|Bacilli S RmuC domain protein rmuC - - ko:K09760 - - - - ko00000 - - - RmuC OGLMJJLJ_01078 264199.stu1794 4.81e-229 630.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli 91061|Bacilli S 3'-5' exoribonuclease yhaM yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon OGLMJJLJ_01079 322159.STER_1765 3.12e-184 513.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli 91061|Bacilli F operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N OGLMJJLJ_01080 1046629.Ssal_00226 1.99e-90 265.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 OGLMJJLJ_01081 1046629.Ssal_00227 3.83e-104 301.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 OGLMJJLJ_01082 264199.stu1789 0.0 1358.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 OGLMJJLJ_01083 264199.stu1788 5.45e-241 662.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli 91061|Bacilli G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N OGLMJJLJ_01084 322159.STER_1413 2.84e-203 562.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli 91061|Bacilli L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve OGLMJJLJ_01085 888048.HMPREF8577_0808 9.96e-130 377.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_01086 322159.STER_0016 1.03e-23 95.9 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - HTH_Tnp_1 OGLMJJLJ_01087 322159.STER_1757 7.18e-57 177.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_Tnp_1 OGLMJJLJ_01088 1046629.Ssal_00123 8.75e-54 171.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,4HBWU@91061|Bacilli 91061|Bacilli L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp OGLMJJLJ_01089 322159.STER_1755 3.18e-281 769.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK OGLMJJLJ_01090 264199.stu1302 2.05e-42 138.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01091 904306.HMPREF9192_0265 1.94e-16 76.3 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01092 322159.STER_1753 1.08e-113 326.0 COG4129@1|root,COG4129@2|Bacteria,1VAJG@1239|Firmicutes,4HKDZ@91061|Bacilli 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - ArAE_1,FUSC_2 OGLMJJLJ_01093 322159.STER_1752 1.12e-83 247.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli 91061|Bacilli K Transcriptional regulator glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 OGLMJJLJ_01094 264199.stu1776 0.0 903.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N OGLMJJLJ_01096 435842.HMPREF0848_01440 9.78e-55 177.0 COG3942@1|root,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4HIMT@91061|Bacilli 91061|Bacilli M CHAP domain protein sle1 - 3.5.1.28 ko:K22409 - - - - ko00000,ko01000 - CBM50 - CHAP,LysM OGLMJJLJ_01097 264199.stu1774 0.0 1103.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL OGLMJJLJ_01098 264199.stu1773 6.45e-45 145.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 OGLMJJLJ_01099 322159.STER_1747 1.38e-155 437.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli 91061|Bacilli O COG1214, inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 OGLMJJLJ_01100 322159.STER_1746 1.54e-96 281.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HP50@91061|Bacilli 91061|Bacilli K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 OGLMJJLJ_01101 264199.stu1770 1.64e-238 656.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 OGLMJJLJ_01102 264199.stu1769 7.55e-150 423.0 COG1296@1|root,COG1296@2|Bacteria,1V64T@1239|Firmicutes,4HH44@91061|Bacilli 91061|Bacilli E AzlC protein XK27_12120 - - - - - - - - - - - AzlC OGLMJJLJ_01103 264199.stu1768 1.91e-63 194.0 COG4392@1|root,COG4392@2|Bacteria 2|Bacteria E branched-chain amino acid azlD - - - - - - - - - - - AzlD OGLMJJLJ_01104 264199.stu1767 0.0 1621.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 OGLMJJLJ_01105 264199.stu1766 1.07e-144 408.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HJSP@91061|Bacilli 91061|Bacilli U Belongs to the peptidase S26 family spi - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 OGLMJJLJ_01106 322159.STER_1740 4.7e-206 570.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII OGLMJJLJ_01108 862969.SCI_0175 1.86e-135 391.0 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,42DYE@671232|Streptococcus anginosus group 91061|Bacilli S Replication initiator protein A (RepA) N-terminus repA - - - - - - - - - - - RepA_N OGLMJJLJ_01109 1035184.HMPREF1042_2353 9.68e-61 188.0 2DIUA@1|root,3044T@2|Bacteria,1TW11@1239|Firmicutes,4I4PX@91061|Bacilli,42EI4@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01110 1035184.HMPREF1042_2352 4.99e-45 148.0 COG4443@1|root,COG4443@2|Bacteria 2|Bacteria S Transcriptional Coactivator p15 (PC4) - - - - - - - - - - - - PC4 OGLMJJLJ_01112 1035184.HMPREF1042_2350 3.21e-132 379.0 2EFFF@1|root,33986@2|Bacteria,1VY42@1239|Firmicutes,4HMPN@91061|Bacilli,42EEK@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - TrbL OGLMJJLJ_01115 1035184.HMPREF1042_2347 0.0 1382.0 COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,4HC47@91061|Bacilli 91061|Bacilli U Psort location Cytoplasmic, score - - - - - - - - - - - - AAA_10,DUF87 OGLMJJLJ_01116 873447.SPB_0377 0.0 1205.0 COG3942@1|root,COG3942@2|Bacteria,1VPFZ@1239|Firmicutes,4HFGV@91061|Bacilli 91061|Bacilli M CHAP domain protein - - - - - - - - - - - - CHAP,Peptidase_M23 OGLMJJLJ_01117 862969.SCI_0185 2.28e-83 253.0 2DNFF@1|root,32X8K@2|Bacteria,1VDM9@1239|Firmicutes,4HNCS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01119 1035184.HMPREF1042_2341 1.89e-94 290.0 2DIU0@1|root,3044E@2|Bacteria,1TW0G@1239|Firmicutes,4I4P6@91061|Bacilli,42EHD@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01120 1035184.HMPREF1042_2340 7.9e-42 152.0 COG3468@1|root,COG3468@2|Bacteria,1UMUJ@1239|Firmicutes,4IU0F@91061|Bacilli,42EFA@671232|Streptococcus anginosus group 91061|Bacilli MU outer membrane autotransporter barrel domain protein - - - - - - - - - - - - - OGLMJJLJ_01121 1035184.HMPREF1042_2339 4.55e-82 247.0 2EDAG@1|root,3376W@2|Bacteria,1VIW8@1239|Firmicutes,4HQS8@91061|Bacilli,42EGT@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01122 862969.SCI_0190 0.0 1070.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4HF20@91061|Bacilli,42E83@671232|Streptococcus anginosus group 91061|Bacilli U Type IV secretory system Conjugative DNA transfer - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf OGLMJJLJ_01124 873447.SPB_0385 0.0 952.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topB - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim OGLMJJLJ_01125 873447.SPB_0386 0.0 1249.0 COG0358@1|root,COG4227@1|root,COG0358@2|Bacteria,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,4HN8F@91061|Bacilli 91061|Bacilli L Psort location Cytoplasmic, score - - - - - - - - - - - - DUF3991,Peptidase_M78,Toprim_2 OGLMJJLJ_01127 1035184.HMPREF1042_2332 2.19e-58 183.0 29Y89@1|root,30K1Z@2|Bacteria,1TTW0@1239|Firmicutes,4I3RM@91061|Bacilli,42EHW@671232|Streptococcus anginosus group 91061|Bacilli S Bacterial mobilisation protein (MobC) - - - - - - - - - - - - MobC OGLMJJLJ_01128 862969.SCI_0195 0.0 898.0 COG3843@1|root,COG3843@2|Bacteria,1V2SB@1239|Firmicutes,4HFEX@91061|Bacilli,42E61@671232|Streptococcus anginosus group 91061|Bacilli U Relaxase/Mobilisation nuclease domain - - - - - - - - - - - - Relaxase OGLMJJLJ_01129 1035184.HMPREF1042_2326 7e-98 288.0 COG1961@1|root,COG1961@2|Bacteria,1UZM8@1239|Firmicutes,4IQ67@91061|Bacilli,42EG7@671232|Streptococcus anginosus group 91061|Bacilli L Resolvase, N terminal domain tnpR - - - - - - - - - - - HTH_23,HTH_7,Resolvase OGLMJJLJ_01130 1069533.Sinf_1782 6.14e-143 408.0 COG1192@1|root,COG1192@2|Bacteria,1V6Q6@1239|Firmicutes,4HINH@91061|Bacilli 91061|Bacilli D CobQ CobB MinD ParA nucleotide binding domain protein - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 OGLMJJLJ_01132 862969.SCI_0200 4.22e-205 580.0 2AQ9M@1|root,31FFI@2|Bacteria,1V8H0@1239|Firmicutes,4ISNC@91061|Bacilli,42EJB@671232|Streptococcus anginosus group 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 OGLMJJLJ_01133 1302863.I872_01550 5.78e-19 80.9 COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA OGLMJJLJ_01134 322159.STER_1738 2.79e-120 344.0 COG1286@1|root,COG1286@2|Bacteria 2|Bacteria S toxin biosynthetic process cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - ko:K03558 - - - - ko00000 - - - Colicin_V,Trypsin_2 OGLMJJLJ_01135 322159.STER_1737 0.0 1476.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr OGLMJJLJ_01136 322159.STER_1736 0.0 1706.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A OGLMJJLJ_01140 264199.stu1757 3.21e-291 793.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 OGLMJJLJ_01142 996306.SSUR61_1077 1.94e-50 176.0 2BJFN@1|root,32DS8@2|Bacteria,1U8WY@1239|Firmicutes,4IIVI@91061|Bacilli,1WSBS@1307|Streptococcus suis 91061|Bacilli - - XK27_05745 - - - - - - - - - - - - OGLMJJLJ_01143 264199.stu1754 3.11e-62 191.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 OGLMJJLJ_01144 264199.stu1753 2.07e-118 338.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB OGLMJJLJ_01145 264199.stu1752 2.03e-47 152.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 OGLMJJLJ_01147 322159.STER_1724 5.91e-159 445.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HJMB@91061|Bacilli 91061|Bacilli S Pfam PF06570 - - - - - - - - - - - - DUF1129 OGLMJJLJ_01148 264199.stu1749 8.18e-216 597.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli 91061|Bacilli P COG0598 Mg2 and Co2 transporters corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA OGLMJJLJ_01149 322159.STER_1722 0.0 1856.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran OGLMJJLJ_01155 435842.HMPREF0848_01406 6.83e-76 230.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes 1239|Firmicutes V 'abc transporter, ATP-binding protein - - - ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 M00254,M00817 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6 - - ABC_tran OGLMJJLJ_01159 264199.stu1742 1.19e-255 701.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli 91061|Bacilli E Belongs to the peptidase M24B family pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 OGLMJJLJ_01160 264199.stu1741 5.83e-109 313.0 COG2131@1|root,COG2131@2|Bacteria,1V8V0@1239|Firmicutes,4IQZA@91061|Bacilli 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 OGLMJJLJ_01161 264199.stu1740 6.05e-127 361.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C OGLMJJLJ_01162 322159.STER_1714 9.01e-81 240.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli 91061|Bacilli S protein conserved in bacteria WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 OGLMJJLJ_01163 264199.stu1738 3.79e-96 280.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB OGLMJJLJ_01164 322159.STER_1712 1.01e-224 620.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9V1@91061|Bacilli 91061|Bacilli K Transcriptional scrR - - ko:K02529,ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 OGLMJJLJ_01165 322159.STER_1711 0.0 999.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N OGLMJJLJ_01166 322159.STER_1710 0.0 1204.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system scrA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC OGLMJJLJ_01167 264199.stu1733 6.81e-220 605.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli 91061|Bacilli GK Fructokinase scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK OGLMJJLJ_01168 264199.stu1732 1.78e-240 659.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI OGLMJJLJ_01170 264199.stu1730 0.0 1647.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW OGLMJJLJ_01171 322159.STER_1704 2.03e-251 689.0 COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes 1239|Firmicutes E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroH - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS07240 DAHP_synth_1 OGLMJJLJ_01172 322159.STER_1703 2.89e-251 689.0 COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes 1239|Firmicutes E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS07240 DAHP_synth_1 OGLMJJLJ_01173 322159.STER_1702 1.23e-80 239.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS OGLMJJLJ_01174 322159.STER_1701 1.72e-246 679.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N OGLMJJLJ_01175 322159.STER_1700 0.0 1311.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge OGLMJJLJ_01176 264199.stu1724 8.08e-223 614.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli 91061|Bacilli EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase OGLMJJLJ_01177 904306.HMPREF9192_0643 0.0 896.0 COG0561@1|root,COG4696@1|root,COG0561@2|Bacteria,COG4696@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily - - - - - - - - - - - - Hydrolase_3,PRA-PH OGLMJJLJ_01178 904306.HMPREF9192_0644 4.09e-24 99.8 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli 91061|Bacilli M Membrane yebC - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 OGLMJJLJ_01179 435842.HMPREF0848_01381 6.94e-126 370.0 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli 91061|Bacilli M Membrane yebC - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 OGLMJJLJ_01180 1046629.Ssal_00311 6.48e-22 93.6 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - - OGLMJJLJ_01181 1046629.Ssal_00311 1.35e-13 72.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - - OGLMJJLJ_01182 1046629.Ssal_00311 6.77e-64 211.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - - OGLMJJLJ_01183 435842.HMPREF0848_01379 3.76e-13 65.9 COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,4HHGZ@91061|Bacilli 91061|Bacilli K LytTr DNA-binding domain protein XK27_02470 - - - - - - - - - - - LytTR OGLMJJLJ_01184 435842.HMPREF0848_01378 1.53e-70 218.0 COG4758@1|root,COG4758@2|Bacteria,1VGSF@1239|Firmicutes,4IRBC@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - - OGLMJJLJ_01185 264199.stu1717 0.0 2115.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C OGLMJJLJ_01186 322159.STER_1681 0.0 2311.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C OGLMJJLJ_01187 904306.HMPREF9192_0656 7.03e-161 452.0 COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,4HEYY@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 OGLMJJLJ_01188 1046629.Ssal_00328 2.59e-172 481.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCEU@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ecsA_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran OGLMJJLJ_01189 322159.STER_1677 0.0 987.0 28MBB@1|root,2ZAPV@2|Bacteria,1TSZA@1239|Firmicutes,4HDKH@91061|Bacilli 91061|Bacilli - - XK27_00765 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - OGLMJJLJ_01190 904306.HMPREF9192_0659 1.01e-181 506.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase OGLMJJLJ_01191 322159.STER_1675 8.59e-290 792.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh OGLMJJLJ_01192 435842.HMPREF0848_01480 2.06e-31 122.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - CAP,Gram_pos_anchor OGLMJJLJ_01193 1046629.Ssal_00333 1.58e-42 143.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli 91061|Bacilli J Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 OGLMJJLJ_01194 264199.stu1704 4.3e-54 179.0 2DDKD@1|root,2ZIF1@2|Bacteria,1W5UA@1239|Firmicutes,4HZND@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01195 264199.stu1704 2.52e-34 125.0 2DDKD@1|root,2ZIF1@2|Bacteria,1W5UA@1239|Firmicutes,4HZND@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01196 264199.stu1704 6.56e-84 256.0 2DDKD@1|root,2ZIF1@2|Bacteria,1W5UA@1239|Firmicutes,4HZND@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01197 322159.STER_1668 1.54e-221 611.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 OGLMJJLJ_01198 322159.STER_1667 3.89e-62 191.0 COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli 91061|Bacilli D cell division protein FtsL ftsL - - - - - - - - - - - DivIC OGLMJJLJ_01199 322159.STER_1666 0.0 1461.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase OGLMJJLJ_01200 322159.STER_1665 8.08e-236 649.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 OGLMJJLJ_01201 322159.STER_1664 2.75e-304 832.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C OGLMJJLJ_01203 322159.STER_1662 0.0 920.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos OGLMJJLJ_01204 264199.stu1697 3.68e-134 384.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli 91061|Bacilli J protein conserved in bacteria yutD - - - - - - - - - - - DUF1027 OGLMJJLJ_01205 322159.STER_1660 7.84e-286 780.0 COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli 91061|Bacilli J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM OGLMJJLJ_01206 264199.stu1695 2.82e-122 348.0 COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HQZW@91061|Bacilli 91061|Bacilli V Glycopeptide antibiotics resistance protein XK27_09885 - - - - - - - - - - - VanZ OGLMJJLJ_01208 264199.stu1694 0.0 1110.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran OGLMJJLJ_01209 264199.stu1693 0.0 1078.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_01211 264199.stu1691 0.0 1363.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA - - ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.112 - - ABC_membrane,ABC_tran,Peptidase_C39 OGLMJJLJ_01212 322159.STER_1652 5.03e-311 849.0 COG0845@1|root,COG0845@2|Bacteria,1V5C8@1239|Firmicutes,4HHKB@91061|Bacilli 91061|Bacilli M Transport protein ComB mesE - - ko:K20345 ko02024,map02024 - - - ko00000,ko00001,ko02000 3.A.1.112,8.A.1 - - HlyD_3 OGLMJJLJ_01214 322159.STER_1650 5.99e-303 828.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity blpH - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 OGLMJJLJ_01215 322159.STER_1649 1.56e-174 486.0 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system agrA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg OGLMJJLJ_01216 862971.SANR_0567 1.08e-34 119.0 2DITH@1|root,3043M@2|Bacteria,1TVYK@1239|Firmicutes,4I4KQ@91061|Bacilli,42EF9@671232|Streptococcus anginosus group 91061|Bacilli S Bacteriocin class II with double-glycine leader peptide - - - - - - - - - - - - Bacteriocin_IIc OGLMJJLJ_01217 862967.SIR_1141 0.000703 39.7 2BCZA@1|root,326KF@2|Bacteria,1TW08@1239|Firmicutes,4I4NU@91061|Bacilli,42EH7@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01223 862971.SANR_0567 1.08e-34 119.0 2DITH@1|root,3043M@2|Bacteria,1TVYK@1239|Firmicutes,4I4KQ@91061|Bacilli,42EF9@671232|Streptococcus anginosus group 91061|Bacilli S Bacteriocin class II with double-glycine leader peptide - - - - - - - - - - - - Bacteriocin_IIc OGLMJJLJ_01224 862967.SIR_1141 0.000313 40.8 2BCZA@1|root,326KF@2|Bacteria,1TW08@1239|Firmicutes,4I4NU@91061|Bacilli,42EH7@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01232 904306.HMPREF9192_0691 1.11e-210 583.0 2DWQH@1|root,341F6@2|Bacteria,1W6SH@1239|Firmicutes,4HX74@91061|Bacilli 91061|Bacilli - - blpT - - - - - - - - - - - Thioredoxin OGLMJJLJ_01233 322159.STER_1636 1.31e-63 194.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding spiA - - ko:K18831 - - - - ko00000,ko02048,ko03000 - - - EntA_Immun,HTH_3,Peptidase_M78,Peptidase_S24 OGLMJJLJ_01236 322159.STER_1633 0.0 1510.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 OGLMJJLJ_01237 264199.stu1671 7.59e-212 584.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HE39@91061|Bacilli 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family gla - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP OGLMJJLJ_01238 322159.STER_0763 6.76e-122 353.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01239 322159.STER_0151 2.66e-132 384.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01240 904306.HMPREF9192_0984 3.16e-206 572.0 COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,4HAXZ@91061|Bacilli 91061|Bacilli E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds - - - - - - - - - - - - HMGL-like OGLMJJLJ_01242 904306.HMPREF9192_0987 1.16e-265 727.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HA76@91061|Bacilli 91061|Bacilli CE Tartrate dehydrogenase ycsA - 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - - Iso_dh OGLMJJLJ_01243 904306.HMPREF9192_0988 7.45e-158 442.0 COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,4HGQE@91061|Bacilli 91061|Bacilli H Methyltransferase - - 4.1.3.17 ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 - R00008,R00350 RC00067,RC00502,RC01205 ko00000,ko00001,ko01000 - - - RraA-like OGLMJJLJ_01244 904306.HMPREF9192_0989 9.52e-197 545.0 COG1735@1|root,COG1735@2|Bacteria,1UKB6@1239|Firmicutes 1239|Firmicutes S metal-dependent hydrolase with the TIM-barrel fold - - - - - - - - - - - - - OGLMJJLJ_01245 575606.HMPREF0525_01168 3.85e-90 273.0 COG1085@1|root,COG1085@2|Bacteria,1TSNU@1239|Firmicutes,4H9TY@91061|Bacilli,3F3JH@33958|Lactobacillaceae 91061|Bacilli C Domain of unknown function (DUF4931) - - - - - - - - - - - - DUF4931 OGLMJJLJ_01246 904306.HMPREF9192_0991 9.04e-205 568.0 COG0697@1|root,COG0697@2|Bacteria,1UZGC@1239|Firmicutes,4HDET@91061|Bacilli 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily yrdR - - - - - - - - - - - EamA OGLMJJLJ_01247 525309.HMPREF0494_0017 4.01e-46 167.0 COG0640@1|root,COG0640@2|Bacteria,1UZT5@1239|Firmicutes 1239|Firmicutes K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 OGLMJJLJ_01248 1008453.HMPREF9957_1401 6.72e-29 112.0 COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes,4HAJS@91061|Bacilli,2TP00@28037|Streptococcus mitis 91061|Bacilli L overlaps another CDS with the same product name - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_01249 322159.STER_0138 1.62e-142 410.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4IR2T@91061|Bacilli 91061|Bacilli L Helix-turn-helix domain of transposase family ISL3 - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01250 322159.STER_0151 4.41e-138 399.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01251 322159.STER_1630 1.05e-175 490.0 COG0346@1|root,COG0346@2|Bacteria,1VMPM@1239|Firmicutes,4HSVM@91061|Bacilli 91061|Bacilli E CppA N-terminal cppA - - - - - - - - - - - CppA_C,CppA_N OGLMJJLJ_01252 264199.stu1667 6.86e-234 643.0 COG1680@1|root,COG1680@2|Bacteria,1TNZX@1239|Firmicutes,4IPJT@91061|Bacilli 91061|Bacilli V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase OGLMJJLJ_01253 762051.LKI_10701 2.76e-42 139.0 2DY5Q@1|root,34896@2|Bacteria,1VZDZ@1239|Firmicutes,4HZ9A@91061|Bacilli,4AY9W@81850|Leuconostocaceae 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01254 322159.STER_1628 1.69e-150 423.0 COG4619@1|root,COG4619@2|Bacteria,1V3DQ@1239|Firmicutes,4HHGU@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ybbL - - ko:K02068 - M00211 - - ko00000,ko00002,ko02000 - - - ABC_tran OGLMJJLJ_01255 264199.stu1665 1.3e-160 452.0 COG0390@1|root,COG0390@2|Bacteria,1UY1N@1239|Firmicutes,4HDM4@91061|Bacilli 91061|Bacilli S transport system, permease component ybbM GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - ko:K02069 - M00211 - - ko00000,ko00002,ko02000 9.B.25.1 - - UPF0014 OGLMJJLJ_01256 264199.stu1664 1.44e-157 442.0 COG1434@1|root,COG1434@2|Bacteria 2|Bacteria S Gram-negative-bacterium-type cell wall biogenesis XK27_05540 - - - - - - - - - - - DUF218 OGLMJJLJ_01257 203120.LEUM_A08 1.67e-75 229.0 COG0582@1|root,COG0582@2|Bacteria,1VEIE@1239|Firmicutes,4HK3N@91061|Bacilli,4AX2E@81850|Leuconostocaceae 91061|Bacilli L Phage integrase family - - - - - - - - - - - - Phage_integrase OGLMJJLJ_01258 264199.stu1663 1.62e-43 144.0 COG0582@1|root,COG0582@2|Bacteria 2|Bacteria L DNA integration - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_integrase OGLMJJLJ_01259 264199.stu1662 3.16e-43 140.0 COG1196@1|root,COG1196@2|Bacteria,1V5Y6@1239|Firmicutes,4HHGT@91061|Bacilli 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Mob_Pre OGLMJJLJ_01260 264199.stu1661 8.06e-56 174.0 COG1196@1|root,COG1196@2|Bacteria,1V5Y6@1239|Firmicutes,4HHGT@91061|Bacilli 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Mob_Pre OGLMJJLJ_01261 264199.stu1660 1.12e-09 56.6 COG0732@1|root,COG0732@2|Bacteria 2|Bacteria V type I restriction modification DNA specificity domain hsdS_1 - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S OGLMJJLJ_01262 322159.STER_1624 3.8e-111 319.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli 91061|Bacilli S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 OGLMJJLJ_01263 264199.stu1658 9.83e-51 166.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli 91061|Bacilli P carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase OGLMJJLJ_01264 322159.STER_1623 3.81e-55 178.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli 91061|Bacilli P carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase OGLMJJLJ_01265 264199.stu1657 0.0 1543.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli 91061|Bacilli C formate acetyltransferase' pflB - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like OGLMJJLJ_01266 322159.STER_1621 7.44e-257 705.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH OGLMJJLJ_01268 264199.stu1654 2.46e-193 537.0 COG0834@1|root,COG0834@2|Bacteria,1V7WQ@1239|Firmicutes,4HK1Z@91061|Bacilli 91061|Bacilli ET ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_01269 264199.stu1653 7.25e-208 577.0 COG0765@1|root,COG0765@2|Bacteria,1UZ2C@1239|Firmicutes,4HF77@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yxeN - - ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 M00236,M00585,M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 - - BPD_transp_1 OGLMJJLJ_01270 322159.STER_1617 9.69e-170 474.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein tcyN - 3.6.3.21 ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 M00234,M00236,M00585 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 - - ABC_tran OGLMJJLJ_01271 40041.SZO_03890 1.81e-14 68.6 29I01@1|root,304X3@2|Bacteria,1TXCH@1239|Firmicutes,4I6AC@91061|Bacilli,1M9T3@119603|Streptococcus dysgalactiae group 91061|Bacilli S Protein of unknown function (DUF4059) - - - - - - - - - - - - DUF4059 OGLMJJLJ_01272 264199.stu1650 1.95e-219 605.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 OGLMJJLJ_01273 322159.STER_1614 1.05e-119 342.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli 91061|Bacilli L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 OGLMJJLJ_01274 264199.stu1648 1.31e-113 326.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like OGLMJJLJ_01275 264199.stu1647 7.32e-248 681.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 OGLMJJLJ_01276 264199.stu1646 3.56e-231 635.0 COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli 91061|Bacilli S radical SAM protein ytqA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C OGLMJJLJ_01277 264199.stu1645 3.01e-125 357.0 COG0144@1|root,COG0144@2|Bacteria,1UHQD@1239|Firmicutes,4HIMC@91061|Bacilli 91061|Bacilli J (SAM)-dependent mraW1 - - - - - - - - - - - rRNA_methylase OGLMJJLJ_01279 264199.stu1643 0.0 1259.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli 91061|Bacilli P NhaP-type Na H and K H antiporters nhaP1 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger OGLMJJLJ_01280 264199.stu1642 7.14e-183 509.0 COG1119@1|root,COG1119@2|Bacteria,1TRR4@1239|Firmicutes,4HB4U@91061|Bacilli 91061|Bacilli P abc transporter atp-binding protein ylmA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran OGLMJJLJ_01281 264199.stu1641 1.17e-303 830.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 OGLMJJLJ_01282 1046629.Ssal_00399 8.42e-194 537.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM OGLMJJLJ_01284 264199.stu1637 6.2e-98 285.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli 91061|Bacilli T universal stress protein XK27_03180 - - - - - - - - - - - Usp OGLMJJLJ_01285 322159.STER_1600 2.61e-303 825.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HD83@91061|Bacilli 91061|Bacilli E Aminotransferase aspC - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 OGLMJJLJ_01286 264199.stu1635 3.67e-181 504.0 COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli 91061|Bacilli K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor codY GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03706 - - - - ko00000,ko03000 - - - CodY,HTH_CodY OGLMJJLJ_01287 322159.STER_1598 5.01e-129 366.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli 91061|Bacilli Q isochorismatase pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - Isochorismatase OGLMJJLJ_01288 264199.stu1633 4.02e-157 444.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli 91061|Bacilli M Belongs to the NlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 OGLMJJLJ_01289 264199.stu1632 3.9e-79 237.0 COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K07304,ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR OGLMJJLJ_01290 904306.HMPREF9192_0728 0.0 890.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family ascB - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 OGLMJJLJ_01291 1046629.Ssal_00409 7.49e-64 195.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln OGLMJJLJ_01292 264199.stu1626 0.0 934.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase OGLMJJLJ_01293 322159.STER_1590 0.0 943.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey OGLMJJLJ_01294 264199.stu1624 1.92e-84 249.0 2B9ZC@1|root,323D0@2|Bacteria,1VBNR@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_01295 322159.STER_1587 2.04e-102 303.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA OGLMJJLJ_01296 264199.stu1623 1.39e-78 241.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA OGLMJJLJ_01297 264199.stu1622 1.84e-127 362.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli 91061|Bacilli S hydrolase of the HAD superfamily yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase OGLMJJLJ_01298 322159.STER_1585 3.79e-273 746.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli 91061|Bacilli S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 OGLMJJLJ_01299 264199.stu1620 1.59e-65 199.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY OGLMJJLJ_01300 264199.stu1619 3.06e-150 422.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like OGLMJJLJ_01301 264199.stu1618 8.21e-139 392.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD OGLMJJLJ_01302 322159.STER_1581 9.81e-77 229.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS OGLMJJLJ_01303 322159.STER_1580 2.78e-179 499.0 COG0500@1|root,COG2226@2|Bacteria,1V24K@1239|Firmicutes,4HDFY@91061|Bacilli 91061|Bacilli Q Methyltransferase domain protein XK27_06665 - - - - - - - - - - - Methyltransf_25 OGLMJJLJ_01304 322159.STER_1579 9.03e-256 702.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 OGLMJJLJ_01305 264199.stu1614 0.0 1318.0 COG0542@1|root,COG0542@2|Bacteria,1TRHP@1239|Firmicutes,4HAHZ@91061|Bacilli 91061|Bacilli O ATP-dependent Clp protease ATP-binding subunit clpL - - ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR OGLMJJLJ_01306 322159.STER_0367 1.85e-285 779.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_01307 1008453.HMPREF9957_0290 1e-21 92.8 2DIAX@1|root,302KA@2|Bacteria,1UD5G@1239|Firmicutes,4IE19@91061|Bacilli,2TNYQ@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01308 435842.HMPREF0848_01249 3.23e-37 129.0 2E9BR@1|root,333JH@2|Bacteria,1VI51@1239|Firmicutes,4HQRQ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - DUF4064 OGLMJJLJ_01310 1000588.HMPREF9965_1970 1.37e-13 67.8 2DKCI@1|root,30963@2|Bacteria,1U4H8@1239|Firmicutes,4IE92@91061|Bacilli,2TPVV@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01311 322159.STER_1573 3.06e-91 267.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli 91061|Bacilli FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT OGLMJJLJ_01312 264199.stu1609 1.68e-168 471.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran OGLMJJLJ_01313 322159.STER_1571 4.26e-229 633.0 COG4473@1|root,COG4473@2|Bacteria,1V1VG@1239|Firmicutes,4HG1K@91061|Bacilli 91061|Bacilli U ABC transporter ecsB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB OGLMJJLJ_01314 264199.stu1607 8.46e-197 544.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli 91061|Bacilli M Phosphotransferase ytmP - - - - - - - - - - - APH OGLMJJLJ_01315 264199.stu1606 1.46e-154 433.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 OGLMJJLJ_01317 264199.stu1605 2.75e-288 786.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli 91061|Bacilli S Flavoprotein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like OGLMJJLJ_01318 322159.STER_1566 0.0 1130.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli 91061|Bacilli E Belongs to the IlvD Edd family ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD OGLMJJLJ_01319 264199.stu1603 8.66e-83 245.0 COG2151@1|root,COG2151@2|Bacteria,1VX9Z@1239|Firmicutes,4HXCM@91061|Bacilli 91061|Bacilli S cog cog2151 XK27_02560 - - - - - - - - - - - FeS_assembly_P OGLMJJLJ_01320 264199.stu1602 1.41e-80 243.0 2EHT6@1|root,33BIW@2|Bacteria,1VNC1@1239|Firmicutes,4HRJ5@91061|Bacilli 91061|Bacilli S Protein of unknown function, DUF536 WQ51_02910 - - - - - - - - - - - DUF536,HTH_11,HTH_24 OGLMJJLJ_01321 264199.stu1601 8.48e-132 374.0 COG0847@1|root,COG0847@2|Bacteria,1V8EQ@1239|Firmicutes,4HJYT@91061|Bacilli 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T OGLMJJLJ_01322 904306.HMPREF9192_0780 1.21e-156 441.0 COG0789@1|root,COG0789@2|Bacteria,1UZ0H@1239|Firmicutes,4HGGU@91061|Bacilli 91061|Bacilli K transcriptional regulator, MerR family - - - - - - - - - - - - MerR_1 OGLMJJLJ_01323 264199.stu1599 5.39e-62 190.0 COG2963@1|root,COG2963@2|Bacteria,1VFYX@1239|Firmicutes,4HNKT@91061|Bacilli 91061|Bacilli L transposase activity - - - - - - - - - - - - HTH_28 OGLMJJLJ_01324 264199.stu1598 5.31e-59 182.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd OGLMJJLJ_01325 563038.HMPREF0851_01449 5.87e-25 99.0 2DEIC@1|root,2ZN3X@2|Bacteria,1W3A8@1239|Firmicutes,4HZMP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01326 1116231.SMA_0321 7.07e-37 132.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_01327 1116231.SMA_1382 4.64e-249 685.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_01328 1005705.HMPREF9967_1422 1.53e-175 494.0 COG0189@1|root,COG0189@2|Bacteria,1TSHN@1239|Firmicutes,4HBFG@91061|Bacilli,43FXH@68892|Streptococcus infantis 91061|Bacilli HJ the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - RimK OGLMJJLJ_01329 888821.HMPREF9394_0461 2.15e-156 454.0 COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli 91061|Bacilli C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family gltT - - ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7 - iYO844.BSU10220 SDF OGLMJJLJ_01330 322159.STER_1963 5.37e-31 109.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like - - - - - - - - - - - - CsbD OGLMJJLJ_01331 264199.stu1986 1.06e-106 310.0 COG1302@1|root,COG1302@2|Bacteria 2|Bacteria M Protein conserved in bacteria - - - - - - - - - - - - Asp23 OGLMJJLJ_01332 1116231.SMA_0314 1.03e-30 108.0 COG5547@1|root,COG5547@2|Bacteria 2|Bacteria S Small integral membrane protein - - - - - - - - - - - - DUF2273 OGLMJJLJ_01333 322159.STER_1960 1.36e-50 164.0 2ED8H@1|root,33752@2|Bacteria,1VK2R@1239|Firmicutes,4HQ99@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01334 525379.HMPREF0819_1359 1.07e-40 139.0 2ED8H@1|root,33752@2|Bacteria,1VK2R@1239|Firmicutes,4HQ99@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01335 322159.STER_1959 1.61e-44 144.0 COG2261@1|root,COG2261@2|Bacteria,1VENK@1239|Firmicutes,4HNKV@91061|Bacilli 91061|Bacilli S Membrane ytgB - - - - - - - - - - - Transgly_assoc OGLMJJLJ_01337 1095726.HMPREF1116_0267 1.24e-132 377.0 COG3548@1|root,COG3548@2|Bacteria 2|Bacteria S protein homotetramerization yiiE - - - - - - - - - - - DUF1211 OGLMJJLJ_01338 1346.DQ08_00960 3.6e-87 262.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli 91061|Bacilli L COG2801 Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve OGLMJJLJ_01339 563038.HMPREF0851_01449 3.34e-36 129.0 2DEIC@1|root,2ZN3X@2|Bacteria,1W3A8@1239|Firmicutes,4HZMP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01340 264199.stu1596 0.0 1472.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli 91061|Bacilli P E1-E2 ATPase ctpE - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase OGLMJJLJ_01341 1046629.Ssal_00451 2.94e-73 220.0 2C4MC@1|root,32RSW@2|Bacteria,1VCIA@1239|Firmicutes,4HKKA@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01342 322159.STER_1555 7.81e-56 174.0 COG1605@1|root,COG1605@2|Bacteria 2|Bacteria E Chorismate mutase MA20_20425 - 2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5 ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R03084,R03460,R06602 RC00350,RC00848,RC01549,RC02148,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 OGLMJJLJ_01343 264199.stu1593 0.0 882.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind OGLMJJLJ_01344 322159.STER_1553 2.47e-136 385.0 COG0512@1|root,COG0512@2|Bacteria,1V4RM@1239|Firmicutes,4HHD8@91061|Bacilli 91061|Bacilli EH anthranilate trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase OGLMJJLJ_01345 322159.STER_1552 2.69e-231 637.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 OGLMJJLJ_01346 322159.STER_1551 2.77e-173 484.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HG9K@91061|Bacilli 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS OGLMJJLJ_01347 322159.STER_1550 3.9e-131 372.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HK18@91061|Bacilli 91061|Bacilli E belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI OGLMJJLJ_01348 322159.STER_1549 2.88e-290 792.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP OGLMJJLJ_01349 264199.stu1587 2.49e-183 510.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA OGLMJJLJ_01350 322159.STER_1547 4.28e-97 282.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli 91061|Bacilli K Copper transport repressor, CopY TcrY family copY - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R OGLMJJLJ_01351 322159.STER_1546 0.0 1343.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase OGLMJJLJ_01352 264199.stu1584 9.48e-43 139.0 COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,4HR1Z@91061|Bacilli 91061|Bacilli P Heavy metal-associated domain protein copZ - - - - - - - - - - - HMA OGLMJJLJ_01353 322159.STER_1544 9.64e-248 680.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N OGLMJJLJ_01354 264199.stu1582 7.05e-148 417.0 COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,4HGE1@91061|Bacilli 91061|Bacilli P ABC transporter (Permease glnP9 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 OGLMJJLJ_01355 1046629.Ssal_00474 3.24e-148 418.0 COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,4HGVA@91061|Bacilli 91061|Bacilli P ABC transporter (Permease glnP7 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 OGLMJJLJ_01356 264199.stu1580 1.11e-171 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HDK7@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran OGLMJJLJ_01357 322159.STER_1539 9.46e-200 553.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli 91061|Bacilli ET ABC transporter substrate-binding protein cjaA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_01361 322159.STER_1534 0.0 893.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M OGLMJJLJ_01362 322159.STER_1533 1.34e-154 434.0 COG5522@1|root,COG5522@2|Bacteria 2|Bacteria S Integral membrane protein (intg_mem_TP0381) ywaF - - - - - - - - - - - Intg_mem_TP0381 OGLMJJLJ_01363 322159.STER_1532 0.0 1034.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C OGLMJJLJ_01364 322159.STER_0151 1.45e-298 815.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01365 322159.STER_1529 6.49e-129 367.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli 91061|Bacilli S Thiamine transporter thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ OGLMJJLJ_01366 264199.stu1570 1.07e-82 244.0 arCOG12631@1|root,3172B@2|Bacteria,1V77G@1239|Firmicutes,4HJ0W@91061|Bacilli 91061|Bacilli S Bacterial PH domain yjqA - - - - - - - - - - - bPH_1 OGLMJJLJ_01367 264199.stu1569 1.45e-203 565.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HCQ6@91061|Bacilli 91061|Bacilli P CorA-like protein corA - - - - - - - - - - - CorA OGLMJJLJ_01368 322159.STER_1526 0.0 885.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C OGLMJJLJ_01369 264199.stu1567 4.12e-56 174.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli 91061|Bacilli L endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG OGLMJJLJ_01370 322159.STER_1524 1.5e-181 505.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli 91061|Bacilli L Methyltransferase yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS OGLMJJLJ_01371 435842.HMPREF0848_01183 8.44e-186 520.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli 91061|Bacilli G deacetylase nodB3 - - - - - - - - - - - Polysacc_deac_1 OGLMJJLJ_01372 322159.STER_1522 2.5e-183 509.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase OGLMJJLJ_01373 322159.STER_1521 2.9e-138 394.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli 91061|Bacilli L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB OGLMJJLJ_01374 322159.STER_1520 0.0 1452.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B OGLMJJLJ_01375 322159.STER_1519 5.05e-296 808.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase OGLMJJLJ_01376 322159.STER_0151 2.93e-298 814.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01377 322159.STER_1518 2.79e-125 357.0 COG1670@1|root,COG1670@2|Bacteria,1V576@1239|Firmicutes,4HH6U@91061|Bacilli 91061|Bacilli J Acetyltransferase GNAT Family XK27_07830 - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 OGLMJJLJ_01378 322159.STER_1517 5.02e-294 804.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli 91061|Bacilli K transcriptional regulator containing CBS domains ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 OGLMJJLJ_01379 322159.STER_1516 2.86e-211 583.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli 91061|Bacilli E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 OGLMJJLJ_01380 322159.STER_1515 3e-205 570.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli 91061|Bacilli E Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB OGLMJJLJ_01381 264199.stu1555 2.79e-111 320.0 COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli 91061|Bacilli S cog cog4708 ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - QueT OGLMJJLJ_01382 264199.stu1554 0.0 1248.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 OGLMJJLJ_01383 322159.STER_1512 1.91e-237 653.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli 91061|Bacilli I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat OGLMJJLJ_01384 264199.stu1552 7.82e-154 431.0 COG1985@1|root,COG1985@2|Bacteria,1UHQR@1239|Firmicutes,4IS6G@91061|Bacilli 91061|Bacilli L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_6 OGLMJJLJ_01385 322159.STER_1509 1.22e-97 285.0 COG4708@1|root,COG4708@2|Bacteria,1V99E@1239|Firmicutes 1239|Firmicutes S QueT transporter - - - - - - - - - - - - QueT OGLMJJLJ_01386 264199.stu1550 9.9e-202 558.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli 91061|Bacilli L exodeoxyribonuclease III xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos OGLMJJLJ_01387 322159.STER_1507 6.55e-220 605.0 COG0500@1|root,COG3615@1|root,COG0500@2|Bacteria,COG3615@2|Bacteria,1TSZK@1239|Firmicutes,4HJT1@91061|Bacilli 91061|Bacilli PQ tellurite resistance protein tehb tehB - 2.1.1.265 ko:K16868 - - - - ko00000,ko01000 - - - DUF1971,TehB OGLMJJLJ_01388 1046629.Ssal_00517 1.87e-57 178.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 OGLMJJLJ_01389 264199.stu1547 9.09e-50 158.0 COG1837@1|root,COG1837@2|Bacteria 2|Bacteria L Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 OGLMJJLJ_01390 264199.stu1546 1.93e-304 830.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08370 Mur_ligase_C,Mur_ligase_M OGLMJJLJ_01391 322159.STER_1503 0.0 1163.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 OGLMJJLJ_01392 264199.stu1544 1.17e-129 368.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli 91061|Bacilli F gtp cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI OGLMJJLJ_01393 264199.stu1543 1.29e-188 524.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind OGLMJJLJ_01394 264199.stu1542 0.0 1023.0 COG0366@1|root,COG0366@2|Bacteria,1TRKZ@1239|Firmicutes,4HC8C@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amy - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1939 OGLMJJLJ_01395 322159.STER_1499 2.48e-80 238.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB OGLMJJLJ_01396 322159.STER_1498 7.94e-114 326.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK OGLMJJLJ_01397 322159.STER_1497 4.06e-219 604.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli 91061|Bacilli M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C OGLMJJLJ_01398 322159.STER_1496 3.94e-272 745.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 OGLMJJLJ_01399 264199.stu1537 2e-179 501.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli 91061|Bacilli P ABC-type spermidine putrescine transport system, permease component I potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 OGLMJJLJ_01400 322159.STER_1494 1.79e-171 480.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli 91061|Bacilli P ABC-type spermidine putrescine transport system, permease component II potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 OGLMJJLJ_01401 264199.stu1535 3.44e-263 720.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli 91061|Bacilli P spermidine putrescine ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 OGLMJJLJ_01402 904306.HMPREF9192_0867 4.81e-25 101.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli 91061|Bacilli O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 OGLMJJLJ_01403 1046629.Ssal_00531 8.14e-47 158.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli 91061|Bacilli O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 OGLMJJLJ_01404 264199.stu1533 1.56e-71 218.0 COG0330@1|root,COG0330@2|Bacteria 2|Bacteria O stress-induced mitochondrial fusion XK27_08050 - - - - - - - - - - - Band_7 OGLMJJLJ_01405 264199.stu1532 1.61e-93 272.0 COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli 91061|Bacilli E Lactoylglutathione lyase gloA - 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 - - Glyoxalase OGLMJJLJ_01406 264199.stu1530 2.56e-70 216.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK OGLMJJLJ_01407 264199.stu1530 4.74e-65 202.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK OGLMJJLJ_01408 322159.STER_1489 8.49e-266 727.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 OGLMJJLJ_01409 264199.stu1528 5.63e-136 384.0 COG1247@1|root,COG1247@2|Bacteria,1UIW7@1239|Firmicutes,4ISU9@91061|Bacilli 91061|Bacilli M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 OGLMJJLJ_01410 322159.STER_1487 6.15e-280 765.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 OGLMJJLJ_01411 904306.HMPREF9192_0874 7.01e-72 218.0 COG0350@1|root,COG0350@2|Bacteria 2|Bacteria L methylated-DNA-[protein]-cysteine S-methyltransferase activity ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.20 ko:K00567,ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N OGLMJJLJ_01412 264199.stu1525 4.16e-78 232.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin OGLMJJLJ_01414 322159.STER_1483 4.04e-77 230.0 COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes 1239|Firmicutes S Effector of murein hydrolase LrgA lrgA - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA OGLMJJLJ_01415 322159.STER_1482 2.27e-151 427.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,4HF0M@91061|Bacilli 91061|Bacilli M effector of murein hydrolase lrgB - - ko:K05339 ko02020,map02020 - - - ko00000,ko00001 - - - LrgB OGLMJJLJ_01416 264199.stu1522 3.33e-126 360.0 COG0546@1|root,COG0546@2|Bacteria,1V421@1239|Firmicutes,4HHYH@91061|Bacilli 91061|Bacilli S IA, variant 1 - - - - - - - - - - - - HAD_2 OGLMJJLJ_01417 264199.stu1521 0.0 1265.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim OGLMJJLJ_01418 264199.stu1520 0.0 1048.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA OGLMJJLJ_01419 264199.stu1519 8.71e-148 416.0 COG0560@1|root,COG0560@2|Bacteria,1V9R7@1239|Firmicutes,4HTNE@91061|Bacilli 91061|Bacilli E phosphoserine phosphatase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD OGLMJJLJ_01420 322159.STER_1477 0.0 2698.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9-BH,Cas9_PI,Cas9_REC,HNH_4 OGLMJJLJ_01421 322159.STER_1476 2.97e-210 580.0 COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,4HC5E@91061|Bacilli 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 OGLMJJLJ_01422 322159.STER_1475 7.78e-69 208.0 COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,4HNYR@91061|Bacilli 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 OGLMJJLJ_01423 322159.STER_1474 1.22e-140 399.0 298VG@1|root,2ZVZK@2|Bacteria,1V1IF@1239|Firmicutes,4HGGM@91061|Bacilli 91061|Bacilli S CRISPR-associated protein (Cas_Csn2) csn2 - - ko:K19137 - - - - ko00000,ko02048 - - - Cas_Csn2 OGLMJJLJ_01425 264199.stu1517 1.88e-196 546.0 COG0697@1|root,COG0697@2|Bacteria,1TYSF@1239|Firmicutes 1239|Firmicutes EG Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA OGLMJJLJ_01427 322159.STER_1470 9.35e-67 202.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein ycaO - - ko:K06889,ko:K07397,ko:K09136 - - - - ko00000,ko03009 - - - Hydrolase_4,OsmC,YcaO OGLMJJLJ_01428 264199.stu1516 7.25e-85 251.0 COG2050@1|root,COG2050@2|Bacteria,1VN0K@1239|Firmicutes,4HM66@91061|Bacilli 91061|Bacilli Q protein possibly involved in aromatic compounds catabolism - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT OGLMJJLJ_01430 658659.HMPREF0983_02893 0.000322 46.6 COG2207@1|root,COG2207@2|Bacteria 2|Bacteria K Transcriptional regulator MA20_01270 - - ko:K13653 - - - - ko00000,ko03000 - - - GyrI-like,HTH_18 OGLMJJLJ_01431 322159.STER_1466 1.18e-168 471.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 OGLMJJLJ_01432 264199.stu1504 1.9e-316 862.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 OGLMJJLJ_01433 1214217.ALNF01000018_gene931 1.84e-24 92.8 29R2M@1|root,30C3R@2|Bacteria,1U94Q@1239|Firmicutes,4IJ5T@91061|Bacilli,1WTRS@1307|Streptococcus suis 91061|Bacilli - - XK27_00735 - - - - - - - - - - - - OGLMJJLJ_01434 322159.STER_1462 1.44e-175 489.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran OGLMJJLJ_01435 322159.STER_1461 0.0 1397.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli 91061|Bacilli P ABC-type amino acid transport signal transduction systems periplasmic component domain glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 OGLMJJLJ_01436 904306.HMPREF9192_0897 5.12e-42 146.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4IQWI@91061|Bacilli 91061|Bacilli S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi OGLMJJLJ_01437 904306.HMPREF9192_0897 5.27e-104 308.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4IQWI@91061|Bacilli 91061|Bacilli S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi OGLMJJLJ_01439 322159.STER_1457 0.0 1282.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB OGLMJJLJ_01440 322159.STER_1456 2.15e-109 314.0 COG1051@1|root,COG1051@2|Bacteria,1V3MM@1239|Firmicutes 1239|Firmicutes F Nudix family XK27_04400 - 3.6.1.55 ko:K03574,ko:K12944 - - - - ko00000,ko01000,ko03400 - - - NUDIX OGLMJJLJ_01441 264199.stu1495 2.08e-181 506.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes 1239|Firmicutes ET Belongs to the bacterial solute-binding protein 3 family XK27_04395 - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_01442 322159.STER_1454 3.08e-173 485.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HJ2R@91061|Bacilli 91061|Bacilli ET ABC transporter XK27_04395 - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_01443 264199.stu1493 1.85e-265 727.0 COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,4HE7P@91061|Bacilli 91061|Bacilli E Aminotransferase arcT - - - - - - - - - - - Aminotran_1_2 OGLMJJLJ_01444 322159.STER_1452 9.99e-176 491.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_01445 1046629.Ssal_00586 1.01e-26 98.6 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 OGLMJJLJ_01446 435842.HMPREF0848_01106 8.05e-63 194.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL OGLMJJLJ_01447 264199.stu1489 0.0 1154.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 OGLMJJLJ_01448 322159.STER_1448 3.03e-257 706.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 OGLMJJLJ_01449 264199.stu1487 4.86e-74 222.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli 91061|Bacilli K metal-sulfur cluster biosynthetic enzyme yitW - - - - - - - - - - - FeS_assembly_P OGLMJJLJ_01450 322159.STER_1446 2.44e-214 592.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli 91061|Bacilli M COG0463, glycosyltransferases involved in cell wall biogenesis yfdH - - ko:K12999,ko:K20534 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 OGLMJJLJ_01451 264199.stu1484 1.5e-312 852.0 2DSN8@1|root,33GRU@2|Bacteria,1VPDR@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_01452 264199.stu1483 1.9e-207 573.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind OGLMJJLJ_01453 904306.HMPREF9192_0915 1.96e-275 756.0 COG2244@1|root,COG2244@2|Bacteria,1V1RP@1239|Firmicutes,4IR8D@91061|Bacilli 91061|Bacilli S membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C OGLMJJLJ_01454 322159.STER_1442 3.57e-236 649.0 COG1216@1|root,COG1216@2|Bacteria,1UJE4@1239|Firmicutes 1239|Firmicutes S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 OGLMJJLJ_01455 322159.STER_1441 9.46e-235 645.0 COG1216@1|root,COG1216@2|Bacteria,1V3XP@1239|Firmicutes,4HQNP@91061|Bacilli 91061|Bacilli S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 OGLMJJLJ_01456 322159.STER_1440 7.71e-167 466.0 COG1215@1|root,COG1215@2|Bacteria,1UHQZ@1239|Firmicutes,4IS6R@91061|Bacilli 91061|Bacilli M group 2 family protein arnC - - ko:K00786 - - - - ko00000,ko01000 - - - Glycos_transf_2 OGLMJJLJ_01457 1046629.Ssal_00599 8e-57 178.0 2EVMS@1|root,33P1S@2|Bacteria,1VPQZ@1239|Firmicutes 1239|Firmicutes S Uncharacterized conserved protein (DUF2304) - - - ko:K09153 - - - - ko00000 - - - DUF2304 OGLMJJLJ_01458 322159.STER_1438 2.34e-196 543.0 COG1216@1|root,COG1216@2|Bacteria,1UI19@1239|Firmicutes 1239|Firmicutes S Glycosyltransferase group 2 family protein - - - - - - - - - - - - Glycos_transf_2 OGLMJJLJ_01459 322159.STER_1437 1.21e-290 791.0 COG0438@1|root,COG0438@2|Bacteria,1V7K7@1239|Firmicutes,4HA9A@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1972) rgpA - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glycos_transf_1 OGLMJJLJ_01460 322159.STER_1436 1.97e-227 626.0 COG0463@1|root,COG0463@2|Bacteria,1V7IQ@1239|Firmicutes,4HK7R@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein rgpB - - ko:K12997 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 OGLMJJLJ_01461 322159.STER_1435 2.29e-183 511.0 COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,4HI7C@91061|Bacilli 91061|Bacilli GM Transport permease protein rgpC - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane OGLMJJLJ_01462 322159.STER_1434 2.11e-291 795.0 COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system rgpD - 3.6.3.40 ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 M00250,M00251,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.103,3.A.1.104 - - ABC_tran,LysM,Wzt_C OGLMJJLJ_01463 322159.STER_1433 0.0 1075.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 OGLMJJLJ_01464 322159.STER_1432 0.0 1190.0 COG3754@1|root,COG3754@2|Bacteria,1V95X@1239|Firmicutes,4HIXP@91061|Bacilli 91061|Bacilli M Rhamnan synthesis protein F rgpF - - ko:K07272 - - - - ko00000,ko01000,ko01003,ko01005 - - - RgpF OGLMJJLJ_01465 322159.STER_1431 0.0 929.0 COG4713@1|root,COG4713@2|Bacteria 2|Bacteria M Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF2142 OGLMJJLJ_01466 322159.STER_1430 5.62e-155 436.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC OGLMJJLJ_01467 904306.HMPREF9192_0931 2.57e-157 442.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli 91061|Bacilli T peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 OGLMJJLJ_01468 322159.STER_1428 1.83e-151 426.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N OGLMJJLJ_01469 264199.stu1462 1.46e-77 231.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 OGLMJJLJ_01470 264199.stu1461 1.12e-264 725.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 OGLMJJLJ_01471 322159.STER_1425 8.64e-227 625.0 COG0462@1|root,COG0462@2|Bacteria,1TQ4I@1239|Firmicutes,4HDRN@91061|Bacilli 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N OGLMJJLJ_01472 264199.stu1458 5.5e-134 380.0 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli 91061|Bacilli S Adenylate cyclase yjbK - - - - - - - - - - - CYTH OGLMJJLJ_01473 264199.stu1459 2.02e-154 434.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli 91061|Bacilli S Gtp pyrophosphokinase yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT OGLMJJLJ_01474 264199.stu1457 4.66e-195 541.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli 91061|Bacilli H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase OGLMJJLJ_01475 264199.stu1456 1.81e-220 607.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 OGLMJJLJ_01476 264199.stu1455 1.56e-231 637.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB OGLMJJLJ_01477 1316408.HSISM1_560 1.16e-48 159.0 COG2963@1|root,COG2963@2|Bacteria,1VDX9@1239|Firmicutes,4HRT2@91061|Bacilli 91061|Bacilli L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_01478 322159.STER_0016 1.03e-23 95.9 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - HTH_Tnp_1 OGLMJJLJ_01479 264199.stu1451 1.61e-123 354.0 COG2801@1|root,COG2801@2|Bacteria,1TRR6@1239|Firmicutes 1239|Firmicutes L PFAM Integrase catalytic region - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_01480 322159.STER_1416 1.61e-274 752.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli 91061|Bacilli P COG0477 Permeases of the major facilitator superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 OGLMJJLJ_01481 525379.HMPREF0819_1242 2.09e-51 168.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli 91061|Bacilli L Hydrolase, tatd tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase OGLMJJLJ_01482 264199.stu1447 1.6e-58 184.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HCM4@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_01483 1046629.Ssal_00627 1.72e-30 114.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HCM4@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_01484 322159.STER_1411 0.0 1281.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 OGLMJJLJ_01485 904306.HMPREF9192_0942 0.0 937.0 COG0601@1|root,COG0601@2|Bacteria,1UY5U@1239|Firmicutes,4HEZK@91061|Bacilli 91061|Bacilli P ABC transporter (Permease amiC GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 OGLMJJLJ_01486 264199.stu1440 2.34e-212 587.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HE8S@91061|Bacilli 91061|Bacilli P ABC transporter (Permease amiD - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N OGLMJJLJ_01487 264199.stu1439 6.91e-259 709.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4H9MR@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_01488 264199.stu1438 1.41e-217 601.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HCM4@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY OGLMJJLJ_01489 322159.STER_1404 3.61e-172 482.0 COG1131@1|root,COG1131@2|Bacteria 2|Bacteria V ATPase activity - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - OGLMJJLJ_01490 264199.stu1436 1.23e-160 450.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HGHM@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein skfE - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran OGLMJJLJ_01491 322159.STER_1402 2.43e-83 246.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli 91061|Bacilli K Transcriptional ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR OGLMJJLJ_01492 322159.STER_1401 1.63e-190 528.0 COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4IPK2@91061|Bacilli 91061|Bacilli S overlaps another CDS with the same product name - - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_01493 322159.STER_1400 5.25e-193 535.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HGA9@91061|Bacilli 91061|Bacilli S overlaps another CDS with the same product name XK27_02985 - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_01494 264199.stu1432 3.13e-309 845.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N OGLMJJLJ_01495 264199.stu1431 8.75e-145 408.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin OGLMJJLJ_01496 264199.stu1430 6.79e-62 190.0 COG1758@1|root,COG1758@2|Bacteria 2|Bacteria K DNA-directed 5'-3' RNA polymerase activity rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 OGLMJJLJ_01497 264199.stu1429 0.0 1571.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII OGLMJJLJ_01498 264199.stu1428 6.31e-223 614.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N OGLMJJLJ_01499 264199.stu1427 4.48e-314 856.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB OGLMJJLJ_01500 264199.stu1426 1.05e-167 470.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 OGLMJJLJ_01501 322159.STER_1392 0.0 1115.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase OGLMJJLJ_01502 264199.stu1422 6.28e-154 433.0 COG4758@1|root,COG4758@2|Bacteria 2|Bacteria KT membrane yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 OGLMJJLJ_01503 264199.stu1421 1.31e-223 618.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 OGLMJJLJ_01504 322159.STER_1387 8.07e-148 416.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli 91061|Bacilli K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg OGLMJJLJ_01507 322159.STER_1384 1.3e-121 347.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM OGLMJJLJ_01508 264199.stu1418 5.68e-174 484.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT OGLMJJLJ_01509 264199.stu1417 5.51e-239 657.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 OGLMJJLJ_01510 264199.stu1416 0.0 1472.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma OGLMJJLJ_01511 1046629.Ssal_00653 3.85e-142 423.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,PUD OGLMJJLJ_01512 904306.HMPREF9192_0969 2.14e-101 313.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,PUD OGLMJJLJ_01513 1046629.Ssal_00653 9.22e-100 311.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,PUD OGLMJJLJ_01514 1046629.Ssal_00654 1.55e-29 115.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 OGLMJJLJ_01515 1069533.Sinf_0805 3.6e-51 162.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_01516 1069533.Sinf_0806 1.29e-87 263.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_01517 1117379.BABA_02482 2.96e-32 119.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli,1ZB1J@1386|Bacillus 91061|Bacilli L COG2801 Transposase and inactivated derivatives tra981A - - ko:K07497 - - - - ko00000 - - - HTH_21,rve OGLMJJLJ_01518 1215915.BN193_02495 3.58e-25 95.5 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - - - - - - - - - - rve,rve_2 OGLMJJLJ_01519 467705.SGO_1359 1.15e-141 407.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,HTH_31 OGLMJJLJ_01520 264199.stu1512 4.13e-15 75.5 COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4HCKJ@91061|Bacilli 91061|Bacilli C Arylsulfatase regulator (Fe-S oxidoreductase) - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM OGLMJJLJ_01521 322159.STER_0367 9.84e-281 767.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_01522 264199.stu1512 1.48e-199 562.0 COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4HCKJ@91061|Bacilli 91061|Bacilli C Arylsulfatase regulator (Fe-S oxidoreductase) - - - ko:K06871 - - - - ko00000 - - - Fer4_12,Radical_SAM OGLMJJLJ_01523 467705.SGO_1358 5.79e-248 694.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_01524 1046629.Ssal_00659 1.78e-68 210.0 COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,4HPE4@91061|Bacilli 91061|Bacilli K Acetyltransferase GNAT Family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 OGLMJJLJ_01525 1046629.Ssal_00660 0.0 944.0 2DI63@1|root,32UAI@2|Bacteria,1VBKU@1239|Firmicutes,4HUJH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3114) - - - - - - - - - - - - DUF1310,DUF3114 OGLMJJLJ_01527 264199.stu1413 0.0 1501.0 COG1181@1|root,COG2918@1|root,COG1181@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshF - 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ATP-grasp_3,Dala_Dala_lig_C,GARS_A,Glu_cys_ligase OGLMJJLJ_01528 264199.stu1412 2.03e-52 165.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter - - - ko:K18996,ko:K19171 - - - - ko00000,ko02048,ko03032 - - - ABC_membrane,ABC_tran,RP-C,RP-C_C,Trans_reg_C OGLMJJLJ_01529 904306.HMPREF9192_0999 8.38e-124 369.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ndvA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_01530 904306.HMPREF9192_1001 4.18e-317 920.0 COG3064@1|root,COG3064@2|Bacteria,1UJ29@1239|Firmicutes,4IT10@91061|Bacilli 91061|Bacilli M M26 IgA1-specific Metallo-endopeptidase C-terminal region zmpB - - ko:K08643 - - - - ko00000,ko01000,ko01002 - - - FIVAR,G5,Gram_pos_anchor,Peptidase_M26_C,Peptidase_M26_N,YSIRK_signal OGLMJJLJ_01531 264199.stu1405 3.26e-32 112.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_01532 264199.stu0038 3.43e-13 63.5 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_01533 264199.stu1403 8.52e-192 535.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 OGLMJJLJ_01534 904306.HMPREF9192_1002 4.49e-28 109.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 OGLMJJLJ_01535 322159.STER_1371 5.25e-279 763.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli 91061|Bacilli G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg OGLMJJLJ_01536 264199.stu1401 0.0 999.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli 91061|Bacilli G UDPglucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf OGLMJJLJ_01537 322159.STER_1369 2.45e-247 678.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd OGLMJJLJ_01538 264199.stu1399 1.49e-251 690.0 COG2017@1|root,COG2017@2|Bacteria,1V5UK@1239|Firmicutes,4HTRY@91061|Bacilli 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim OGLMJJLJ_01539 322159.STER_1367 0.0 1181.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli 91061|Bacilli G transporter lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 OGLMJJLJ_01540 264199.stu1397 0.0 2102.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli 91061|Bacilli G -beta-galactosidase lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N OGLMJJLJ_01541 264199.stu1395 5.35e-292 797.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C OGLMJJLJ_01542 264199.stu1394 0.0 1686.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli 91061|Bacilli L ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C OGLMJJLJ_01543 1280671.AUJH01000010_gene3571 3.86e-34 132.0 28ITE@1|root,2Z8SB@2|Bacteria,1V146@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_01544 1403946.Q615_SPAC00123G0004 6.07e-59 182.0 COG2963@1|root,COG2963@2|Bacteria,1V9ZX@1239|Firmicutes,4HKN9@91061|Bacilli 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_01545 1403946.Q615_SPAC00123G0003 1.11e-78 239.0 COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,4HCHG@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve OGLMJJLJ_01546 1123299.AUKZ01000032_gene1329 7e-53 166.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - - - - - - - - - - HTH_21,rve,rve_3 OGLMJJLJ_01548 322159.STER_0151 5.07e-299 816.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01549 1123299.AUKZ01000011_gene1075 2.75e-91 267.0 COG3654@1|root,COG3654@2|Bacteria,1VCC8@1239|Firmicutes,4HKXW@91061|Bacilli 91061|Bacilli S Prophage maintenance system killer protein doc - - ko:K07341 - - - - ko00000,ko02048 - - - Fic OGLMJJLJ_01550 1321372.AQQB01000076_gene537 9.8e-41 134.0 2B3ZK@1|root,31WPQ@2|Bacteria,1U996@1239|Firmicutes,4IJBS@91061|Bacilli,1WU2Q@1307|Streptococcus suis 91061|Bacilli S Antidote-toxin recognition MazE, bacterial antitoxin - - - - - - - - - - - - MazE_antitoxin OGLMJJLJ_01551 264199.stu1386 2.39e-11 65.5 2CWIF@1|root,32SZQ@2|Bacteria,1VBXK@1239|Firmicutes,4HWJ5@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01552 1403946.Q615_SPAC00123G0004 3.52e-58 180.0 COG2963@1|root,COG2963@2|Bacteria,1V9ZX@1239|Firmicutes,4HKN9@91061|Bacilli 91061|Bacilli L COG2963 Transposase and inactivated derivatives - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_01553 1403946.Q615_SPAC00123G0003 1.79e-28 108.0 COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,4HCHG@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - - - - - - - - - - HTH_21,rve OGLMJJLJ_01554 1123299.AUKZ01000032_gene1329 7e-53 166.0 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - - - - - - - - - - HTH_21,rve,rve_3 OGLMJJLJ_01555 1069533.Sinf_0805 3.6e-51 162.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_01556 264199.stu1392 0.0 1394.0 COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1VATJ@1239|Firmicutes,4HG1M@91061|Bacilli 91061|Bacilli M family 8 - - - - - - - - - - - - Glyco_transf_8,Glycos_transf_2 OGLMJJLJ_01557 1027396.LMOSA_12070 0.0 1080.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli,26IQ9@186820|Listeriaceae 91061|Bacilli V Type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase OGLMJJLJ_01558 904306.HMPREF9192_1167 1.3e-90 287.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes 1239|Firmicutes V type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S OGLMJJLJ_01559 345219.Bcoa_1815 0.0 1378.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli,1ZCG9@1386|Bacillus 91061|Bacilli L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII OGLMJJLJ_01562 264199.stu1386 2.25e-190 537.0 2CWIF@1|root,32SZQ@2|Bacteria,1VBXK@1239|Firmicutes,4HWJ5@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01563 322159.STER_1339 0.0 911.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH OGLMJJLJ_01564 264199.stu1384 5.86e-79 234.0 2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HQG9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01566 904306.HMPREF9192_1034 4.2e-86 272.0 2EXVW@1|root,33R50@2|Bacteria,1V0E0@1239|Firmicutes,4HBMI@91061|Bacilli 91061|Bacilli S Signal peptide protein, YSIRK family - - - - - - - - - - - - Gram_pos_anchor,SSURE,YSIRK_signal OGLMJJLJ_01567 1203590.HMPREF1481_01686 4.43e-71 219.0 COG0745@1|root,COG0745@2|Bacteria,1V4S4@1239|Firmicutes,4HH0U@91061|Bacilli 91061|Bacilli K response regulator saeR GO:0008150,GO:0010468,GO:0019222,GO:0050789,GO:0060255,GO:0065007 - ko:K10682 ko02020,map02020 M00468 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C OGLMJJLJ_01569 322159.STER_1332 0.0 979.0 COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,4HDNX@91061|Bacilli 91061|Bacilli S Belongs to the UPF0371 family XK27_07020 - - - - - - - - - - - DUF1846 OGLMJJLJ_01570 904306.HMPREF9192_1063 5.3e-229 631.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd OGLMJJLJ_01571 322159.STER_1326 3.58e-202 559.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli 91061|Bacilli C reductase yvgN - - - - - - - - - - - Aldo_ket_red OGLMJJLJ_01572 904306.HMPREF9192_1065 9.23e-35 124.0 COG3619@1|root,COG3619@2|Bacteria,1V9ME@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 OGLMJJLJ_01573 322159.STER_1325 3.42e-90 268.0 COG3619@1|root,COG3619@2|Bacteria,1V9ME@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 OGLMJJLJ_01574 264199.stu1369 2.02e-143 405.0 COG0778@1|root,COG0778@2|Bacteria,1UYJU@1239|Firmicutes,4HBVQ@91061|Bacilli 91061|Bacilli C Nitroreductase ydgI - - - - - - - - - - - Nitroreductase OGLMJJLJ_01575 322159.STER_1323 1.19e-294 806.0 COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celB - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC OGLMJJLJ_01576 322159.STER_1322 3.06e-202 560.0 COG4814@1|root,COG4814@2|Bacteria,1V13S@1239|Firmicutes,4HENM@91061|Bacilli 91061|Bacilli E Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 OGLMJJLJ_01577 264199.stu1366 6.99e-99 287.0 COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli 91061|Bacilli K Transcriptional regulator ywnA_2 - - - - - - - - - - - Rrf2 OGLMJJLJ_01578 264199.stu1086 2.78e-152 436.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01579 1046629.Ssal_00039 2.9e-129 376.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01580 322159.STER_1320 3.85e-193 536.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase OGLMJJLJ_01581 264199.stu1363 1.65e-140 397.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli 91061|Bacilli S nitroreductase XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase OGLMJJLJ_01582 435842.HMPREF0848_00939 2.24e-08 54.3 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red OGLMJJLJ_01583 435842.HMPREF0848_00939 8.66e-91 273.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red OGLMJJLJ_01584 1046629.Ssal_00802 1.31e-85 259.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red OGLMJJLJ_01585 889204.HMPREF9423_0305 9.82e-107 310.0 COG1309@1|root,COG1309@2|Bacteria,1V2BY@1239|Firmicutes,4HPW3@91061|Bacilli 91061|Bacilli K WHG domain - - - - - - - - - - - - TetR_N,WHG OGLMJJLJ_01586 1316408.HSISM1_1672 3.17e-118 342.0 COG1136@1|root,COG1136@2|Bacteria,1U3WD@1239|Firmicutes,4HV7M@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran OGLMJJLJ_01587 1095727.HMPREF1117_1383 3.87e-28 111.0 28K0P@1|root,2Z9QJ@2|Bacteria,1TSN2@1239|Firmicutes,4HU6K@91061|Bacilli 91061|Bacilli P FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX OGLMJJLJ_01588 1046629.Ssal_00807 7.75e-54 169.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HN2M@91061|Bacilli 91061|Bacilli S Sugar efflux transporter for intercellular exchange - - - - - - - - - - - - MtN3_slv OGLMJJLJ_01589 435842.HMPREF0848_00934 7.97e-108 311.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli 91061|Bacilli O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx OGLMJJLJ_01590 435842.HMPREF0848_00933 1.63e-215 597.0 COG0407@1|root,COG0407@2|Bacteria,1TNYE@1239|Firmicutes,4HQ5B@91061|Bacilli 91061|Bacilli H Uroporphyrinogen decarboxylase (URO-D) - - 4.1.1.37 ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03197,R04972 RC00872 ko00000,ko00001,ko00002,ko01000 - - - URO-D OGLMJJLJ_01591 435842.HMPREF0848_00932 8.82e-207 572.0 COG0834@1|root,COG0834@2|Bacteria,1UX4B@1239|Firmicutes,4HG72@91061|Bacilli 91061|Bacilli ET ABC transporter substrate-binding protein - - - ko:K16957 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - SBP_bac_3 OGLMJJLJ_01592 435842.HMPREF0848_00931 6.18e-144 408.0 COG0765@1|root,COG0765@2|Bacteria,1V4Q3@1239|Firmicutes,4HDVS@91061|Bacilli 91061|Bacilli P ABC transporter (Permease - - - ko:K16958 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 OGLMJJLJ_01593 435842.HMPREF0848_00930 5.78e-148 418.0 COG0765@1|root,COG0765@2|Bacteria,1V1PT@1239|Firmicutes,4HI18@91061|Bacilli 91061|Bacilli P ABC transporter, permease protein - - - ko:K16959 ko02010,map02010 M00585 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.13 - - BPD_transp_1 OGLMJJLJ_01594 435842.HMPREF0848_00929 1.81e-173 484.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein tcyC2 - - ko:K10010,ko:K16960 ko02010,map02010 M00234,M00585 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 - - ABC_tran OGLMJJLJ_01597 1161413.HMPREF1510_1836 3.59e-28 107.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_01598 435842.HMPREF0848_00928 2.36e-177 523.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,Glyco_hydro_25,NLPC_P60,PG_binding_1 OGLMJJLJ_01599 435842.HMPREF0848_00928 5.1e-47 167.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,Glyco_hydro_25,NLPC_P60,PG_binding_1 OGLMJJLJ_01600 435842.HMPREF0848_00928 5e-19 86.3 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,Glyco_hydro_25,NLPC_P60,PG_binding_1 OGLMJJLJ_01601 1046629.Ssal_00817 3.48e-84 275.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 OGLMJJLJ_01602 264199.stu1361 3.24e-294 807.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli 91061|Bacilli E amino acid yfnA - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 OGLMJJLJ_01604 264199.stu1360 5.5e-34 117.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like csbD - - - - - - - - - - - CsbD OGLMJJLJ_01605 264199.stu1359 3.23e-75 224.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI OGLMJJLJ_01606 264199.stu1358 2.22e-85 251.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI OGLMJJLJ_01607 322159.STER_1315 6.95e-300 820.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli 91061|Bacilli E Component of the transport system for branched-chain amino acids brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans OGLMJJLJ_01608 1123298.KB904062_gene865 3.98e-231 641.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase hipO2 - - ko:K01436,ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 OGLMJJLJ_01610 1123298.KB904062_gene864 9.92e-129 377.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli 91061|Bacilli C glycerol dehydrogenase - - - ko:K08317 - - - - ko00000,ko01000 - - - Fe-ADH OGLMJJLJ_01611 1123298.KB904062_gene863 2.84e-185 526.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli 91061|Bacilli E mutations do not affect methionine salvage in vivo however ykrV3 - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 OGLMJJLJ_01612 1123298.KB904062_gene862 2.82e-141 418.0 COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,4IS19@91061|Bacilli 91061|Bacilli S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD OGLMJJLJ_01613 1123298.KB904062_gene861 1.13e-74 229.0 COG0454@1|root,COG0456@2|Bacteria,1VC6Z@1239|Firmicutes,4ISI0@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 OGLMJJLJ_01614 1423806.JCM15457_2516 6.27e-94 281.0 COG0765@1|root,COG0765@2|Bacteria,1UZ2C@1239|Firmicutes,4HF77@91061|Bacilli,3F7IY@33958|Lactobacillaceae 91061|Bacilli U ABC transporter, permease protein yxeN - - ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 M00236,M00585,M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 - - BPD_transp_1 OGLMJJLJ_01615 1123298.KB904062_gene859 1.08e-117 343.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein yxeO - - ko:K16963 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran OGLMJJLJ_01616 1123298.KB904062_gene858 7.71e-250 694.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HDVU@91061|Bacilli 91061|Bacilli F Adenylosuccinate lyase - - 4.3.2.2,5.5.1.2 ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 M00048,M00049 R01083,R03307,R04559 RC00379,RC00444,RC00445,RC00902 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 OGLMJJLJ_01617 1123298.KB904062_gene857 4.45e-117 343.0 COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HDQ8@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family yxeM - - ko:K16961 ko02010,map02010 M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_01618 264199.stu1343 2.01e-241 662.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR OGLMJJLJ_01619 322159.STER_1313 4.63e-316 862.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE OGLMJJLJ_01620 264199.stu1340 4.09e-76 232.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K03458,ko:K16169 - - - - ko00000,ko02000 2.A.40,2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease OGLMJJLJ_01621 435842.HMPREF0848_00913 2.27e-177 503.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K16169 - - - - ko00000,ko02000 2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease OGLMJJLJ_01622 904306.HMPREF9192_1089 8.62e-101 294.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran OGLMJJLJ_01623 1046629.Ssal_00835 6.11e-158 443.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli 91061|Bacilli KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain graR - - ko:K19082 ko02020,map02020 M00734,M00737 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C OGLMJJLJ_01624 264199.stu1335 4.75e-220 608.0 COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4HG2J@91061|Bacilli 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c OGLMJJLJ_01625 435842.HMPREF0848_00909 4.26e-171 478.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli 91061|Bacilli V ABC transporter, ATP-binding protein yxdL - - ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - ABC_tran OGLMJJLJ_01626 264199.stu1333 0.0 1159.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli 91061|Bacilli V ABC transporter (permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX OGLMJJLJ_01627 264199.stu1332 2.68e-47 151.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding XK27_05000 - - ko:K06940 - - - - ko00000 - - - CxxCxxCC OGLMJJLJ_01628 904306.HMPREF9192_1096 5.99e-109 313.0 COG0295@1|root,COG0295@2|Bacteria,1V58S@1239|Firmicutes,4HHTM@91061|Bacilli 91061|Bacilli F cytidine deaminase activity - - - - - - - - - - - - dCMP_cyt_deam_1 OGLMJJLJ_01629 264199.stu1330 4.53e-212 587.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli 91061|Bacilli S Transporter yocS - - ko:K03453 - - - - ko00000 2.A.28 - iYO844.BSU19350 SBF OGLMJJLJ_01632 435842.HMPREF0848_00891 5.92e-203 562.0 COG1131@1|root,COG1131@2|Bacteria,1UZ04@1239|Firmicutes,4HDGQ@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein XK27_09825 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran OGLMJJLJ_01633 322159.STER_1292 6.55e-167 467.0 COG0842@1|root,COG0842@2|Bacteria,1V1AU@1239|Firmicutes 1239|Firmicutes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 OGLMJJLJ_01634 322159.STER_1291 1.7e-240 663.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 OGLMJJLJ_01635 904306.HMPREF9192_1103 8.09e-132 375.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg OGLMJJLJ_01636 264199.stu1316 1.13e-76 235.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli 91061|Bacilli E L-serine dehydratase sdaAB - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta OGLMJJLJ_01637 264199.stu1315 0.0 1058.0 COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N OGLMJJLJ_01638 264199.stu1314 1.2e-262 719.0 COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,4HBM2@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF917) - - - ko:K09703 - - - - ko00000 - - - DUF917 OGLMJJLJ_01639 264199.stu1313 0.0 958.0 COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,4H9YS@91061|Bacilli 91061|Bacilli E Histidine ammonia-lyase - - 4.3.1.3 ko:K01745 ko00340,ko01100,map00340,map01100 M00045 R01168 RC00361 ko00000,ko00001,ko00002,ko01000 - - - Lyase_aromatic OGLMJJLJ_01640 264199.stu1312 1.46e-132 378.0 COG1174@1|root,COG1174@2|Bacteria,1V41S@1239|Firmicutes,4HH8U@91061|Bacilli 91061|Bacilli P ABC transporter (Permease proWZ - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 OGLMJJLJ_01641 264199.stu1311 2.63e-212 587.0 COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HESS@91061|Bacilli 91061|Bacilli M ABC transporter, substrate-binding protein, QAT family proWY - - ko:K05845 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - OpuAC OGLMJJLJ_01642 264199.stu1310 3.14e-177 494.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran,CBS OGLMJJLJ_01643 264199.stu1309 5.06e-121 349.0 COG1174@1|root,COG1174@2|Bacteria,1V24D@1239|Firmicutes,4IQR7@91061|Bacilli 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1 OGLMJJLJ_01644 264199.stu1307 4.45e-27 105.0 COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes 1239|Firmicutes E hydrolase yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 OGLMJJLJ_01645 264199.stu1307 3.72e-48 159.0 COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes 1239|Firmicutes E hydrolase yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 OGLMJJLJ_01646 322159.STER_1280 0.0 1174.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N OGLMJJLJ_01647 264199.stu1305 0.0 954.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N OGLMJJLJ_01648 435842.HMPREF0848_00623 0.000385 42.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01649 322159.STER_1276 3.2e-121 345.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli 91061|Bacilli M acetyltransferase pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 OGLMJJLJ_01650 322159.STER_1275 9.59e-103 298.0 COG4912@1|root,COG4912@2|Bacteria 2|Bacteria L Dna alkylation repair alkD - - - - - - - - - - - DNA_alkylation OGLMJJLJ_01651 322159.STER_1274 6.84e-253 694.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC OGLMJJLJ_01652 322159.STER_1273 6.31e-223 614.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS OGLMJJLJ_01653 264199.stu1296 6.47e-161 451.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm OGLMJJLJ_01654 264199.stu1295 0.0 1940.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge OGLMJJLJ_01655 264199.stu1294 5.02e-250 687.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d OGLMJJLJ_01656 264199.stu1293 6.18e-120 342.0 COG0454@1|root,COG0456@2|Bacteria,1VDFK@1239|Firmicutes,4HMHW@91061|Bacilli 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases XK27_03150 - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 OGLMJJLJ_01657 322159.STER_1267 0.0 1531.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind OGLMJJLJ_01659 264199.stu1289 2.66e-74 222.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes 1239|Firmicutes F Ribonucleoside-triphosphate reductase nrdD_1 - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC OGLMJJLJ_01660 322159.STER_1264 4.39e-306 834.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HBNK@91061|Bacilli 91061|Bacilli K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ycxD - - - - - - - - - - - Aminotran_1_2,GntR OGLMJJLJ_01662 264199.stu1285 1.46e-112 323.0 COG4720@1|root,COG4720@2|Bacteria,1V6QK@1239|Firmicutes 1239|Firmicutes S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS OGLMJJLJ_01663 264199.stu1284 1.27e-53 175.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli 91061|Bacilli H Belongs to the pyridoxine kinase family pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin OGLMJJLJ_01664 264199.stu1284 1.15e-110 323.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli 91061|Bacilli H Belongs to the pyridoxine kinase family pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin OGLMJJLJ_01665 322159.STER_1260 2.69e-14 68.9 COG4720@1|root,COG4720@2|Bacteria,1VC0F@1239|Firmicutes,4HMJM@91061|Bacilli 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS OGLMJJLJ_01666 1116231.SMA_0321 2.39e-233 643.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_01667 322159.STER_1260 3.89e-78 235.0 COG4720@1|root,COG4720@2|Bacteria,1VC0F@1239|Firmicutes,4HMJM@91061|Bacilli 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS OGLMJJLJ_01668 322159.STER_1259 0.0 1004.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein yheS_1 - - - - - - - - - - - ABC_tran,ABC_tran_Xtn OGLMJJLJ_01669 322159.STER_1258 0.0 889.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli 91061|Bacilli P NADH oxidase noxE - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim OGLMJJLJ_01670 264199.stu1280 6.88e-231 636.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N OGLMJJLJ_01671 322159.STER_1256 0.0 1447.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV OGLMJJLJ_01672 322159.STER_1255 2.18e-169 474.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HIA0@91061|Bacilli 91061|Bacilli M Sortase (surface protein transpeptidase) srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase OGLMJJLJ_01673 264199.stu1276 9.68e-70 210.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes 1239|Firmicutes E COG0346 LactoylglutaTHIone lyase and related lyases ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase OGLMJJLJ_01674 264199.stu1275 9.81e-212 587.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli 91061|Bacilli S secreted protein ypuA - - - - - - - - - - - DUF1002 OGLMJJLJ_01675 264199.stu1274 2.38e-79 236.0 COG3547@1|root,COG3547@2|Bacteria 2|Bacteria L Transposase (IS116 IS110 IS902 family) - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 OGLMJJLJ_01676 264199.stu1273 6.81e-92 269.0 COG3547@1|root,COG3547@2|Bacteria 2|Bacteria L Transposase (IS116 IS110 IS902 family) - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 OGLMJJLJ_01678 264199.stu1271 6.93e-236 648.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm OGLMJJLJ_01679 264199.stu1270 0.0 1427.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN OGLMJJLJ_01680 264199.stu1269 2.77e-45 146.0 COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin OGLMJJLJ_01681 264199.stu1268 0.0 1745.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C OGLMJJLJ_01682 264199.stu1267 4.25e-271 741.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli 91061|Bacilli C Belongs to the citrate synthase family citZ - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt OGLMJJLJ_01683 264199.stu1266 1.4e-280 767.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli 91061|Bacilli C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh OGLMJJLJ_01684 264199.stu1265 3.31e-52 164.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli 91061|Bacilli G phosphocarrier protein Hpr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr OGLMJJLJ_01685 264199.stu1264 0.0 1089.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C OGLMJJLJ_01686 264199.stu1263 0.0 916.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gapN GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 - - - Aldedh OGLMJJLJ_01687 322159.STER_1240 2.36e-38 128.0 COG1181@1|root,COG1181@2|Bacteria 2|Bacteria F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.2,6.3.2.4 ko:K01919,ko:K01921 ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502 M00118 R00894,R01150,R10993 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N OGLMJJLJ_01688 322159.STER_1239 1.85e-242 668.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C OGLMJJLJ_01689 264199.stu1260 9.1e-148 416.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK OGLMJJLJ_01690 264199.stu1259 0.0 1214.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn OGLMJJLJ_01692 264199.stu1257 2.49e-168 470.0 COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli 91061|Bacilli S Alpha beta hydrolase - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 OGLMJJLJ_01693 264199.stu1256 0.0 1637.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli 91061|Bacilli J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM OGLMJJLJ_01694 264199.stu1255 4.17e-192 532.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 OGLMJJLJ_01695 264199.stu1254 0.0 876.0 COG0771@1|root,COG0771@2|Bacteria,1UHPI@1239|Firmicutes,4HVP0@91061|Bacilli 91061|Bacilli M Mur ligase, middle domain protein murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M OGLMJJLJ_01696 264199.stu1253 1.91e-159 449.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N OGLMJJLJ_01697 322159.STER_1231 1.16e-214 594.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR OGLMJJLJ_01698 264199.stu1251 1.29e-315 860.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV OGLMJJLJ_01699 264199.stu1250 2.02e-92 271.0 COG2246@1|root,COG2246@2|Bacteria,1VMS6@1239|Firmicutes,4HNB7@91061|Bacilli 91061|Bacilli S GtrA-like protein mesH - - - - - - - - - - - GtrA OGLMJJLJ_01700 264199.stu1249 2.59e-160 449.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK OGLMJJLJ_01701 264199.stu1248 1.15e-189 526.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 OGLMJJLJ_01702 1046629.Ssal_01342 3.79e-28 108.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip OGLMJJLJ_01703 1046629.Ssal_01342 9.18e-131 375.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip OGLMJJLJ_01704 264199.stu1245 4.65e-259 710.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli 91061|Bacilli E oxidoreductase yurR - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO OGLMJJLJ_01705 264199.stu1244 1.58e-205 568.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli 91061|Bacilli M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase OGLMJJLJ_01706 264199.stu1243 9.6e-143 402.0 COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli 91061|Bacilli M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rmlC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom OGLMJJLJ_01707 264199.stu1242 9.48e-264 721.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd OGLMJJLJ_01710 322159.STER_0367 2.52e-283 774.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_01711 264199.stu1236 6.59e-277 756.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM OGLMJJLJ_01712 264199.stu1235 6.41e-184 510.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE OGLMJJLJ_01713 322159.STER_1214 6.89e-184 511.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like OGLMJJLJ_01714 322159.STER_1213 4.7e-156 437.0 COG4478@1|root,COG4478@2|Bacteria,1VGZ1@1239|Firmicutes,4HNTM@91061|Bacilli 91061|Bacilli S tigr01906 - - - - - - - - - - - - DUF1461 OGLMJJLJ_01715 322159.STER_1212 9.8e-181 502.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HGYX@91061|Bacilli 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisJ - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - OGLMJJLJ_01716 1046629.Ssal_01327 2.83e-17 80.5 COG4632@1|root,COG4632@2|Bacteria,1TR6Z@1239|Firmicutes,4HGB0@91061|Bacilli 91061|Bacilli G Exopolysaccharide biosynthesis protein XK27_08080 - - - - - - - - - - - NAGPA OGLMJJLJ_01717 322159.STER_1210 1.88e-113 327.0 COG4632@1|root,COG4632@2|Bacteria,1TR6Z@1239|Firmicutes,4HGB0@91061|Bacilli 91061|Bacilli G Exopolysaccharide biosynthesis protein XK27_08080 - - - - - - - - - - - NAGPA OGLMJJLJ_01718 435842.HMPREF0848_00449 3.5e-41 138.0 2EJUK@1|root,33DJ8@2|Bacteria,1VM50@1239|Firmicutes 1239|Firmicutes - - XK27_08085 - - - - - - - - - - - - OGLMJJLJ_01719 322159.STER_0016 3.31e-106 310.0 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - HTH_Tnp_1 OGLMJJLJ_01720 264199.stu0206 4.06e-13 64.7 COG2801@1|root,COG2801@2|Bacteria 2|Bacteria L transposition - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_01721 1161413.HMPREF1510_1836 5.72e-41 141.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_01723 322159.STER_1207 4.99e-251 689.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 OGLMJJLJ_01724 322159.STER_1206 5.26e-234 644.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His OGLMJJLJ_01725 322159.STER_1205 3.99e-149 420.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His OGLMJJLJ_01726 322159.STER_1204 8.41e-298 813.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh OGLMJJLJ_01727 322159.STER_1203 3.35e-137 388.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD OGLMJJLJ_01728 322159.STER_1202 3.88e-140 396.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHNQ@91061|Bacilli 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase OGLMJJLJ_01729 322159.STER_1201 7.66e-163 456.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli 91061|Bacilli E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth OGLMJJLJ_01730 322159.STER_1200 2.2e-173 484.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth OGLMJJLJ_01731 322159.STER_1199 4.95e-79 234.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH OGLMJJLJ_01732 1046629.Ssal_01315 5.16e-66 201.0 COG0140@1|root,COG0140@2|Bacteria 2|Bacteria E phosphoribosyl-ATP diphosphatase activity hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH OGLMJJLJ_01733 322159.STER_1197 1.61e-308 845.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE OGLMJJLJ_01734 264199.stu1228 6.73e-285 780.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 OGLMJJLJ_01735 264199.stu1227 2.71e-150 422.0 COG4468@1|root,COG4468@2|Bacteria,1VY8D@1239|Firmicutes,4HXPD@91061|Bacilli 91061|Bacilli G UDPglucose--hexose-1-phosphate uridylyltransferase XK27_05445 - - - - - - - - - - - - OGLMJJLJ_01736 264199.stu1226 4.43e-222 612.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 OGLMJJLJ_01737 322159.STER_1192 1.82e-178 497.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short OGLMJJLJ_01738 322159.STER_1191 0.0 1427.0 COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli 91061|Bacilli L Single-stranded-DNA-specific exonuclease recj recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C OGLMJJLJ_01739 264199.stu1223 6.44e-122 347.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran OGLMJJLJ_01740 322159.STER_1189 2.81e-232 638.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS OGLMJJLJ_01741 264199.stu1221 7.42e-162 453.0 COG3935@1|root,COG3935@2|Bacteria 2|Bacteria - - dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2 OGLMJJLJ_01742 264199.stu1220 3.81e-154 432.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD OGLMJJLJ_01745 264199.stu1218 1.83e-313 855.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 OGLMJJLJ_01746 264199.stu1217 1.72e-40 134.0 COG1722@1|root,COG1722@2|Bacteria 2|Bacteria L exodeoxyribonuclease VII activity xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S OGLMJJLJ_01747 264199.stu1216 1.64e-203 563.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt OGLMJJLJ_01748 264199.stu1215 3.85e-201 557.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 OGLMJJLJ_01749 322159.STER_1180 5.12e-96 280.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C OGLMJJLJ_01750 322159.STER_1179 0.0 1050.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N OGLMJJLJ_01751 264199.stu1212 2.29e-188 524.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli 91061|Bacilli S DegV family WQ51_01275 - - - - - - - - - - - DegV OGLMJJLJ_01752 1046629.Ssal_01285 3.28e-57 186.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli 91061|Bacilli E COG2755 Lysophospholipase L1 and related esterases XK27_03630 - - - - - - - - - - - Lipase_GDSL_2 OGLMJJLJ_01753 264199.stu1211 1.26e-112 327.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family ypmR GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0016298,GO:0016787,GO:0016788,GO:0052689 - - - - - - - - - - Lipase_GDSL_2 OGLMJJLJ_01754 264199.stu1210 4.93e-123 352.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ypmS - - - - - - - - - - - DUF2140 OGLMJJLJ_01755 264199.stu1209 1.54e-52 166.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding OGLMJJLJ_01757 322159.STER_1173 2.31e-230 633.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBFE@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of dihydroorotate to orotate pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh OGLMJJLJ_01758 264199.stu1204 3.05e-169 472.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 OGLMJJLJ_01759 322159.STER_1171 0.0 1005.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer OGLMJJLJ_01760 264199.stu1202 7.51e-242 665.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli 91061|Bacilli CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU28270 Iso_dh OGLMJJLJ_01761 322159.STER_1169 1.64e-57 178.0 COG3326@1|root,COG3326@2|Bacteria 2|Bacteria L Membrane ysdA - - - - - - - - - - - CSD,DUF1294 OGLMJJLJ_01762 322159.STER_1168 0.0 944.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase OGLMJJLJ_01763 264199.stu1200 2.76e-146 411.0 COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C OGLMJJLJ_01764 264199.stu1199 1.99e-194 538.0 COG0009@1|root,COG0009@2|Bacteria,1U3HQ@1239|Firmicutes,4HFGZ@91061|Bacilli 91061|Bacilli J Belongs to the SUA5 family XK27_00020 - - - - - - - - - - - Sua5_yciO_yrdC OGLMJJLJ_01765 322159.STER_1165 0.0 2031.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon OGLMJJLJ_01766 264199.stu1197 2.99e-239 659.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK OGLMJJLJ_01767 264199.stu1196 0.0 947.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C OGLMJJLJ_01768 264199.stu0126 1.85e-145 414.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01769 322159.STER_0151 2.53e-137 397.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01772 888833.HMPREF9421_1411 1.12e-33 129.0 COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1TV1Y@1239|Firmicutes,4HBHJ@91061|Bacilli 91061|Bacilli Q the current gene model (or a revised gene model) may contain a frame shift crpB - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal OGLMJJLJ_01773 999425.HMPREF9186_00339 2.53e-37 141.0 COG2373@1|root,COG4886@1|root,COG2373@2|Bacteria,COG4886@2|Bacteria,1TV1Y@1239|Firmicutes,4HBHJ@91061|Bacilli 91061|Bacilli Q the current gene model (or a revised gene model) may contain a frame shift crpB - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal OGLMJJLJ_01774 759913.SDSE_0917 5.6e-17 74.7 2DJ86@1|root,304YI@2|Bacteria,1TXEZ@1239|Firmicutes,4I6DB@91061|Bacilli,1MA57@119603|Streptococcus dysgalactiae group 91061|Bacilli S Domain of unknown function (DUF4649) - - - - - - - - - - - - DUF4649 OGLMJJLJ_01775 322159.STER_1155 8.54e-223 616.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HE7G@91061|Bacilli 91061|Bacilli S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind OGLMJJLJ_01776 264199.stu1189 3.93e-190 530.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 OGLMJJLJ_01777 264199.stu1188 5.4e-174 486.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran OGLMJJLJ_01778 264199.stu1187 0.0 1062.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL OGLMJJLJ_01779 264199.stu1186 7.21e-192 531.0 COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4IPZQ@91061|Bacilli 91061|Bacilli S Putative esterase estA - - ko:K03930 - - - - ko00000,ko01000 - CE1 - Esterase OGLMJJLJ_01780 264199.stu1185 3.64e-161 452.0 COG5549@1|root,COG5549@2|Bacteria,1VW9X@1239|Firmicutes,4HWF8@91061|Bacilli 91061|Bacilli O Zinc-dependent metalloprotease XK27_08875 - - - - - - - - - - - Peptidase_M10 OGLMJJLJ_01782 435842.HMPREF0848_00535 3.48e-98 285.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli 91061|Bacilli C Flavodoxin ykuP - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 OGLMJJLJ_01783 264199.stu1182 0.0 972.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli 91061|Bacilli P Chloride transporter, ClC family eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC OGLMJJLJ_01784 264199.stu1181 1.27e-55 173.0 COG1605@1|root,COG1605@2|Bacteria 2|Bacteria E Chorismate mutase pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5 ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_2667 ACT,CM_2,PDT OGLMJJLJ_01785 322159.STER_1145 4.32e-279 764.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HBN3@91061|Bacilli 91061|Bacilli P chloride - - - - - - - - - - - - Voltage_CLC OGLMJJLJ_01786 264199.stu1179 5.73e-75 224.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 OGLMJJLJ_01788 1046629.Ssal_01245 9.42e-28 100.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 OGLMJJLJ_01789 264199.stu1177 2.04e-207 575.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli 91061|Bacilli J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT OGLMJJLJ_01790 322159.STER_1139 3.2e-116 333.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 OGLMJJLJ_01791 322159.STER_1138 0.0 1031.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 OGLMJJLJ_01792 322159.STER_1136 2.38e-223 615.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli 91061|Bacilli HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 OGLMJJLJ_01793 264199.stu1172 5.84e-266 731.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N OGLMJJLJ_01794 322159.STER_1134 6.31e-43 161.0 COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes 1239|Firmicutes GM Psort location CytoplasmicMembrane, score - - 5.1.3.2 ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,RmlD_sub_bind OGLMJJLJ_01795 322159.STER_1125 5.18e-251 687.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd OGLMJJLJ_01797 322159.STER_1123 1.45e-296 810.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase OGLMJJLJ_01798 264199.stu1166 4.09e-35 119.0 2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4HRG1@91061|Bacilli 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA OGLMJJLJ_01799 264199.stu1165 5.22e-181 507.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2,Endonuclease_NS OGLMJJLJ_01800 264199.stu1164 2.48e-143 405.0 COG0765@1|root,COG0765@2|Bacteria,1V14N@1239|Firmicutes,4HJ9W@91061|Bacilli 91061|Bacilli P ABC transporter (permease) - - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 OGLMJJLJ_01801 322159.STER_1119 7.97e-157 441.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HE9C@91061|Bacilli 91061|Bacilli P ABC transporter (Permease XK27_07620 - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 OGLMJJLJ_01802 322159.STER_1118 8.04e-193 535.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli 91061|Bacilli ET ABC-type amino acid transport signal transduction systems, periplasmic component domain peb1A - - ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 M00228,M00232,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 OGLMJJLJ_01803 322159.STER_1117 5.43e-180 501.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran OGLMJJLJ_01804 322159.STER_1116 2.49e-166 465.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli 91061|Bacilli KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C OGLMJJLJ_01805 322159.STER_1115 5.5e-315 858.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 OGLMJJLJ_01806 322159.STER_1114 1.7e-195 541.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli 91061|Bacilli S Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 OGLMJJLJ_01807 322159.STER_1113 5.94e-46 148.0 COG2832@1|root,COG2832@2|Bacteria 2|Bacteria F Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 OGLMJJLJ_01808 264199.stu1155 1.49e-293 801.0 COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,4HC1Z@91061|Bacilli 91061|Bacilli V protein involved in methicillin resistance femX - 2.3.2.10,2.3.2.16 ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 - R08776,R08779 RC00055,RC00096 ko00000,ko00001,ko01000,ko01011 - - - FemAB OGLMJJLJ_01809 264199.stu1154 5.66e-189 525.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily XK27_00835 - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_01810 322159.STER_1109 3.98e-59 183.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase XK27_00115 - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 OGLMJJLJ_01811 264199.stu1151 1.69e-89 262.0 COG4506@1|root,COG4506@2|Bacteria 2|Bacteria S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 OGLMJJLJ_01812 322159.STER_1107 0.0 1638.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli 91061|Bacilli P cation transport ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase OGLMJJLJ_01813 264199.stu1149 8.01e-174 485.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase OGLMJJLJ_01814 264199.stu1147 9.04e-233 639.0 COG1409@1|root,COG1409@2|Bacteria,1V9B5@1239|Firmicutes,4HJX0@91061|Bacilli 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos OGLMJJLJ_01815 322159.STER_1104 1.52e-263 721.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 OGLMJJLJ_01816 264199.stu1146 9.24e-231 636.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 OGLMJJLJ_01817 264199.stu1145 1.04e-159 448.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli 91061|Bacilli D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran OGLMJJLJ_01818 322159.STER_1100 1.34e-207 575.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX OGLMJJLJ_01819 264199.stu1143 3.52e-120 342.0 COG1051@1|root,COG1051@2|Bacteria,1V66I@1239|Firmicutes,4HHRE@91061|Bacilli 91061|Bacilli F NTP pyrophosphohydrolases including oxidative damage repair enzymes mutX - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX OGLMJJLJ_01820 264199.stu1142 1.22e-231 643.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli 91061|Bacilli S permease XK27_05220 - - - - - - - - - - - AI-2E_transport OGLMJJLJ_01821 264199.stu1141 2.22e-284 778.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli 91061|Bacilli G COG0457 FOG TPR repeat XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 OGLMJJLJ_01822 322159.STER_1096 1.32e-125 358.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli 91061|Bacilli U Belongs to the peptidase S26 family sipC - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 OGLMJJLJ_01823 264199.stu1139 1.27e-291 796.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 OGLMJJLJ_01824 264199.stu1138 1.79e-116 333.0 2FI04@1|root,349T2@2|Bacteria,1VQ5S@1239|Firmicutes,4HYC5@91061|Bacilli 91061|Bacilli S Family of unknown function (DUF5322) ebsA - - - - - - - - - - - DUF5322 OGLMJJLJ_01825 264199.stu1136 1.4e-46 159.0 COG1388@1|root,COG1388@2|Bacteria,1VD79@1239|Firmicutes,4HT02@91061|Bacilli 91061|Bacilli M LysM domain XK27_09115 - - - - - - - - - - - LysM OGLMJJLJ_01826 322159.STER_1090 8.33e-156 437.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin OGLMJJLJ_01827 322159.STER_1089 4.47e-115 330.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HI4P@91061|Bacilli 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N OGLMJJLJ_01828 264199.stu1133 1.66e-38 128.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p OGLMJJLJ_01829 1046629.Ssal_01190 1.82e-73 221.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 OGLMJJLJ_01830 264199.stu1807 4.47e-108 311.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,4HGN6@91061|Bacilli 91061|Bacilli L Transposase - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp OGLMJJLJ_01831 264199.stu1129 3.77e-54 172.0 COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,4HKYX@91061|Bacilli 91061|Bacilli K Gnat family XK27_03610 - - - - - - - - - - - Acetyltransf_1 OGLMJJLJ_01832 264199.stu1128 2.78e-37 125.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase OGLMJJLJ_01833 264199.stu1127 0.0 948.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli 91061|Bacilli E Dipeptidase pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 OGLMJJLJ_01834 322159.STER_1082 1.95e-145 409.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli 91061|Bacilli L Uracil-DNA glycosylase ung2 - - - - - - - - - - - UDG OGLMJJLJ_01835 435842.HMPREF0848_00593 2.23e-31 123.0 COG3266@1|root,COG3266@2|Bacteria,1VU2V@1239|Firmicutes,4HU5W@91061|Bacilli 91061|Bacilli V Glucan-binding protein C - - - - - - - - - - - - GbpC,Gram_pos_anchor,YSIRK_signal OGLMJJLJ_01836 1316408.HSISM1_134 9.18e-12 65.1 COG3266@1|root,COG3266@2|Bacteria,1VU2V@1239|Firmicutes,4HU5W@91061|Bacilli 91061|Bacilli V Glucan-binding protein C - - - - - - - - - - - - GbpC,Gram_pos_anchor,YSIRK_signal OGLMJJLJ_01838 264199.stu1121 2.91e-156 439.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A OGLMJJLJ_01839 322159.STER_1077 2.7e-300 818.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme OGLMJJLJ_01840 264199.stu1118 5.38e-54 171.0 COG3797@1|root,COG3797@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 OGLMJJLJ_01841 322159.STER_1075 3.56e-192 533.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 OGLMJJLJ_01842 904306.HMPREF9192_1672 9.23e-110 326.0 COG0038@1|root,COG0038@2|Bacteria,1V07H@1239|Firmicutes 1239|Firmicutes P chloride clcA2 - - - - - - - - - - - Voltage_CLC OGLMJJLJ_01843 904306.HMPREF9192_1673 1.12e-86 259.0 COG0518@1|root,COG0518@2|Bacteria,1V97T@1239|Firmicutes,4HIKV@91061|Bacilli 91061|Bacilli F glutamine amidotransferase gat - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase OGLMJJLJ_01844 904306.HMPREF9192_1673 2.67e-48 160.0 COG0518@1|root,COG0518@2|Bacteria,1V97T@1239|Firmicutes,4HIKV@91061|Bacilli 91061|Bacilli F glutamine amidotransferase gat - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase OGLMJJLJ_01845 322159.STER_1072 4.46e-165 462.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli 91061|Bacilli F purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 OGLMJJLJ_01846 322159.STER_1071 0.0 870.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HDRS@91061|Bacilli 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein cps4A - - - - - - - - - - - DNA_PPF,LytR_cpsA_psr OGLMJJLJ_01847 322159.STER_1070 1.56e-173 484.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli 91061|Bacilli GM Capsular polysaccharide biosynthesis protein cpsB - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - OGLMJJLJ_01848 264199.stu1110 7.53e-145 410.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli 91061|Bacilli M biosynthesis protein capA - - - - - - - - - - - GNVR,Wzz OGLMJJLJ_01849 322159.STER_1068 1.23e-151 429.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli 91061|Bacilli D COG0489 ATPases involved in chromosome partitioning cpsD - - - - - - - - - - - AAA_31 OGLMJJLJ_01850 264199.stu1108 0.0 870.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB3Z@91061|Bacilli 91061|Bacilli M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase cpsE - - - - - - - - - - - Bac_transf,CoA_binding_3 OGLMJJLJ_01851 904306.HMPREF9192_1679 1.84e-280 766.0 COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,4IPU2@91061|Bacilli 91061|Bacilli M group 1 family protein rgpAc - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glycos_transf_1 OGLMJJLJ_01852 1116231.SMA_0863 7.51e-262 719.0 COG0438@1|root,COG0438@2|Bacteria,1TR6R@1239|Firmicutes,4HEIZ@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 OGLMJJLJ_01853 904306.HMPREF9192_1681 1.62e-95 281.0 COG3955@1|root,COG3955@2|Bacteria,1V8R9@1239|Firmicutes,4HW77@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1919) - - - - - - - - - - - - DUF1919 OGLMJJLJ_01855 862970.SAIN_1722 1.94e-153 440.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4ISVG@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glyco_trans_1_2,Glycos_transf_2 OGLMJJLJ_01856 862970.SAIN_1721 3.79e-189 531.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4HN74@91061|Bacilli 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 OGLMJJLJ_01857 862970.SAIN_1720 2.75e-219 612.0 2BVGB@1|root,32U6R@2|Bacteria,1VC7Z@1239|Firmicutes,4HNDJ@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01858 904306.HMPREF9192_1685 7.92e-307 840.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HC84@91061|Bacilli 91061|Bacilli S Polysaccharide biosynthesis protein wzx - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C OGLMJJLJ_01859 1069533.Sinf_0727 1.54e-271 742.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,4HB5F@91061|Bacilli 91061|Bacilli M UDP-galactopyranose mutase glf - 5.4.99.9 ko:K01854 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - GLF,NAD_binding_8 OGLMJJLJ_01860 1069533.Sinf_0729 3.61e-244 671.0 COG0438@1|root,COG0438@2|Bacteria,1UZFG@1239|Firmicutes,4ISTK@91061|Bacilli 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - OGLMJJLJ_01862 322159.STER_0763 6.9e-83 251.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01863 322159.STER_0138 2.13e-48 165.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,4IR2T@91061|Bacilli 91061|Bacilli L Helix-turn-helix domain of transposase family ISL3 - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01864 322159.STER_1054 9.91e-124 353.0 COG4767@1|root,COG4767@2|Bacteria,1VA6K@1239|Firmicutes,4HKNU@91061|Bacilli 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ OGLMJJLJ_01865 1046629.Ssal_01165 3.02e-20 87.4 COG0561@1|root,COG0561@2|Bacteria,1V1SQ@1239|Firmicutes,4IPTG@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase supH - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_01866 264199.stu1071 6.86e-80 237.0 COG0561@1|root,COG0561@2|Bacteria 2|Bacteria Q phosphatase activity supH - 3.1.3.102,3.1.3.104 ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00548,R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 OGLMJJLJ_01867 1046629.Ssal_01162 1.88e-132 376.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 OGLMJJLJ_01868 322159.STER_1050 1.68e-254 700.0 COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli 91061|Bacilli S hmm pf01594 XK27_12525 - - - - - - - - - - - AI-2E_transport OGLMJJLJ_01869 1123318.KB904593_gene1608 1.74e-22 95.1 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 OGLMJJLJ_01870 1046629.Ssal_01160 5.61e-172 490.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 OGLMJJLJ_01871 322159.STER_1048 3.34e-52 165.0 COG3937@1|root,COG3937@2|Bacteria,1VK6K@1239|Firmicutes,4HRS5@91061|Bacilli 91061|Bacilli S granule-associated protein - - - - - - - - - - - - - OGLMJJLJ_01872 322159.STER_1047 0.0 1010.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli 91061|Bacilli S unusual protein kinase ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH OGLMJJLJ_01873 904306.HMPREF9192_1701 3.14e-38 132.0 COG2755@1|root,COG2755@2|Bacteria,1VHUN@1239|Firmicutes,4IPN1@91061|Bacilli 91061|Bacilli E Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 OGLMJJLJ_01874 322159.STER_1045 3.75e-90 265.0 COG2755@1|root,COG2755@2|Bacteria,1V1B9@1239|Firmicutes,4HGED@91061|Bacilli 91061|Bacilli E GDSL-like protein - - - - - - - - - - - - Lipase_GDSL_2 OGLMJJLJ_01875 322159.STER_1044 4.34e-200 554.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli 91061|Bacilli S Phospholipase, patatin family - - - - - - - - - - - - Patatin OGLMJJLJ_01876 264199.stu1059 4.49e-162 457.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HD0P@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA1 - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - DUF1958,Peptidase_S11 OGLMJJLJ_01877 264199.stu1059 1.12e-31 118.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HD0P@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA1 - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - DUF1958,Peptidase_S11 OGLMJJLJ_01878 264199.stu1058 3.05e-31 109.0 COG1686@1|root,COG1686@2|Bacteria 2|Bacteria M Belongs to the peptidase S11 family dacA1 - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - DUF1958,PBP5_C,Peptidase_S11 OGLMJJLJ_01879 322159.STER_1042 5.21e-275 753.0 COG0053@1|root,COG4994@1|root,COG0053@2|Bacteria,COG4994@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer OGLMJJLJ_01880 322159.STER_1041 3.31e-162 453.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes 1239|Firmicutes L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG OGLMJJLJ_01881 264199.stu1054 3.43e-299 816.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 OGLMJJLJ_01882 1046629.Ssal_01151 0.0 1144.0 COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - DUF2207 OGLMJJLJ_01883 322159.STER_1036 6.17e-236 648.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli 91061|Bacilli C Dehydrogenase E1 component acoA - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh OGLMJJLJ_01884 264199.stu1050 3.38e-232 640.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit acoB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C OGLMJJLJ_01885 264199.stu1049 3.51e-274 756.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex acoC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding OGLMJJLJ_01886 322159.STER_1033 0.0 1105.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli 91061|Bacilli C Dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim OGLMJJLJ_01887 904306.HMPREF9192_1715 3.53e-15 76.3 COG0860@1|root,COG1705@1|root,COG3757@1|root,COG5263@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,COG3757@2|Bacteria,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - 3.5.1.28 ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 - - - Amidase_3,CW_binding_1,GBS_Bsp-like,Glucosaminidase,Glyco_hydro_25,Peptidase_C39_2 OGLMJJLJ_01888 264199.stu1046 7.95e-87 255.0 COG3757@1|root,COG3757@2|Bacteria 2|Bacteria M lysozyme activity - - 3.2.1.17 ko:K01185,ko:K07273 - - - - ko00000,ko01000 - - - GBS_Bsp-like,Glyco_hydro_25,LysM OGLMJJLJ_01889 322159.STER_1030 5.95e-238 654.0 COG0860@1|root,COG0860@2|Bacteria,1W25V@1239|Firmicutes,4HGXW@91061|Bacilli 91061|Bacilli M GBS Bsp-like repeat - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,CHAP,GBS_Bsp-like,Glyco_hydro_25 OGLMJJLJ_01890 1046629.Ssal_01131 2.03e-158 479.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal OGLMJJLJ_01891 264199.stu1033 1.89e-83 256.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal OGLMJJLJ_01892 1046629.Ssal_01131 5.89e-70 234.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal OGLMJJLJ_01893 264199.stu1031 4.24e-111 321.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal OGLMJJLJ_01894 1046629.Ssal_01131 2.83e-41 151.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal OGLMJJLJ_01895 322159.STER_1024 1.06e-200 556.0 COG2822@1|root,COG2822@2|Bacteria,1TS89@1239|Firmicutes,4HB0W@91061|Bacilli 91061|Bacilli P periplasmic lipoprotein involved in iron transport ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - ko:K07224 - - - - ko00000,ko02000 2.A.108.2.3 - - Peptidase_M75 OGLMJJLJ_01896 322159.STER_1023 7.41e-297 809.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli 91061|Bacilli P peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal OGLMJJLJ_01897 322159.STER_1022 0.0 1037.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease ywbL - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 OGLMJJLJ_01898 322159.STER_1021 2.02e-156 440.0 COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC OGLMJJLJ_01899 264199.stu1020 4.79e-34 117.0 COG1826@1|root,COG1826@2|Bacteria 2|Bacteria U protein secretion tatA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 OGLMJJLJ_01900 264199.stu1444 1.25e-201 564.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01901 264199.stu0129 2.06e-63 196.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01902 904306.HMPREF9192_1726 2.59e-256 710.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli 91061|Bacilli P ABC transporter (Permease malF - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 OGLMJJLJ_01903 1046629.Ssal_01117 9.18e-214 597.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4H9TU@91061|Bacilli 91061|Bacilli G ABC transporter malX - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_8 OGLMJJLJ_01904 1046629.Ssal_01117 9.16e-25 101.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4H9TU@91061|Bacilli 91061|Bacilli G ABC transporter malX - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_8 OGLMJJLJ_01905 264199.stu1014 1.12e-59 192.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli 91061|Bacilli K Transcriptional regulator malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 OGLMJJLJ_01906 264199.stu1014 8.02e-80 245.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli 91061|Bacilli K Transcriptional regulator malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 OGLMJJLJ_01907 264199.stu1013 0.0 1036.0 COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,4HCHB@91061|Bacilli 91061|Bacilli G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 OGLMJJLJ_01908 322159.STER_1016 0.0 1495.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase OGLMJJLJ_01912 322159.STER_1014 7.23e-238 654.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C OGLMJJLJ_01913 322159.STER_1013 2.19e-248 682.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli 91061|Bacilli D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase OGLMJJLJ_01914 264199.stu1007 0.0 1672.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 OGLMJJLJ_01915 322159.STER_1011 7.71e-148 417.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU OGLMJJLJ_01916 322159.STER_1010 1.75e-179 499.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran OGLMJJLJ_01917 322159.STER_1009 5.27e-193 535.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran OGLMJJLJ_01918 322159.STER_1008 7.15e-200 555.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli 91061|Bacilli P phosphate transport system permease pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 OGLMJJLJ_01919 264199.stu1002 4.63e-201 558.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 OGLMJJLJ_01920 322159.STER_1006 3.99e-200 555.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli 91061|Bacilli P phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 OGLMJJLJ_01921 322159.STER_1005 0.0 884.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI OGLMJJLJ_01922 322159.STER_1004 6.89e-183 508.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P OGLMJJLJ_01923 264199.stu0998 9.86e-59 181.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 OGLMJJLJ_01924 264199.stu0997 1.15e-89 263.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC OGLMJJLJ_01925 264199.stu0996 6.55e-221 608.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase OGLMJJLJ_01926 264199.stu0995 2.43e-194 540.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N OGLMJJLJ_01927 904306.HMPREF9192_1747 2.02e-60 197.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli 91061|Bacilli S hemerythrin HHE cation binding domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 OGLMJJLJ_01928 904306.HMPREF9192_1747 5.12e-93 285.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli 91061|Bacilli S hemerythrin HHE cation binding domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 OGLMJJLJ_01929 264199.stu0993 1.33e-98 292.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli 91061|Bacilli S hemerythrin HHE cation binding domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 OGLMJJLJ_01930 435842.HMPREF0848_00681 4.87e-45 145.0 COG2461@1|root,COG2461@2|Bacteria 2|Bacteria P Hemerythrin HHE cation binding domain protein M1-755 - - ko:K09155 - - - - ko00000 - - - DUF1858,DUF438,Hemerythrin,PAS_10 OGLMJJLJ_01931 264199.stu0991 3.31e-143 404.0 COG0732@1|root,COG0732@2|Bacteria,1VQES@1239|Firmicutes,4HE4K@91061|Bacilli 91061|Bacilli V Type I restriction modification DNA specificity domain hsdS2 - - - - - - - - - - - Methylase_S OGLMJJLJ_01932 264199.stu0990 3.49e-113 325.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin OGLMJJLJ_01933 904306.HMPREF9192_1752 7.95e-171 478.0 COG0561@1|root,COG0561@2|Bacteria,1TQTU@1239|Firmicutes,4HEHK@91061|Bacilli 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 OGLMJJLJ_01934 322159.STER_0995 1.71e-306 836.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli 91061|Bacilli E o-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP OGLMJJLJ_01935 322159.STER_0994 0.0 1419.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C OGLMJJLJ_01936 322159.STER_0993 2.03e-306 837.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli 91061|Bacilli E (Alanine) symporter agcS - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp OGLMJJLJ_01937 322159.STER_0992 5.47e-316 862.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N OGLMJJLJ_01938 1046629.Ssal_01085 1.16e-29 113.0 COG2207@1|root,COG2207@2|Bacteria,1UZG6@1239|Firmicutes,4HCQS@91061|Bacilli 91061|Bacilli K Transcriptional regulator bglC - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC OGLMJJLJ_01939 264199.stu0981 7.73e-93 273.0 COG4977@1|root,COG4977@2|Bacteria 2|Bacteria K sequence-specific DNA binding yfiF3 - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC OGLMJJLJ_01940 1046629.Ssal_01083 1e-27 112.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family sasH - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos OGLMJJLJ_01942 699248.SRA_05851 3.33e-67 211.0 COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yckA GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 OGLMJJLJ_01943 264199.stu0975 1.46e-76 229.0 COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family yckB - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 OGLMJJLJ_01944 264199.stu0974 9.86e-80 238.0 COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family yckB - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 OGLMJJLJ_01945 264199.stu0973 7.91e-133 380.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase OGLMJJLJ_01946 322159.STER_0984 0.0 912.0 COG3104@1|root,COG3104@2|Bacteria,1TP81@1239|Firmicutes,4HAF2@91061|Bacilli 91061|Bacilli E transporter dtpT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03305 - - - - ko00000 2.A.17 - - PTR2 OGLMJJLJ_01947 435842.HMPREF0848_00691 3.73e-79 249.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase OGLMJJLJ_01948 322159.STER_0981 4.34e-145 409.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran OGLMJJLJ_01949 264199.stu0967 7.15e-164 458.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase OGLMJJLJ_01950 1046629.Ssal_01079 2.29e-224 619.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh OGLMJJLJ_01951 264199.stu0954 6.89e-189 525.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli 91061|Bacilli C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iYO844.BSU15530 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 OGLMJJLJ_01952 264199.stu0953 3.52e-124 354.0 COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,4HM36@91061|Bacilli 91061|Bacilli S DJ-1 family thiJ - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI OGLMJJLJ_01953 904306.HMPREF9192_1767 3.76e-105 309.0 2B4EH@1|root,31X62@2|Bacteria,1V7WE@1239|Firmicutes,4HJ8G@91061|Bacilli 91061|Bacilli S TraX protein - - - - - - - - - - - - TraX OGLMJJLJ_01954 904306.HMPREF9192_1767 0.000908 41.2 2B4EH@1|root,31X62@2|Bacteria,1V7WE@1239|Firmicutes,4HJ8G@91061|Bacilli 91061|Bacilli S TraX protein - - - - - - - - - - - - TraX OGLMJJLJ_01955 264199.stu0950 0.0 1068.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA OGLMJJLJ_01957 904306.HMPREF9192_1770 8.1e-19 85.1 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli 91061|Bacilli V Mate efflux family protein dinF - - - - - - - - - - - MatE OGLMJJLJ_01958 264199.stu0946 5.35e-26 100.0 COG0534@1|root,COG0534@2|Bacteria 2|Bacteria V drug transmembrane transporter activity - - - - - - - - - - - - MatE OGLMJJLJ_01959 1046629.Ssal_01070 2.64e-23 97.8 COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,4HAMP@91061|Bacilli 91061|Bacilli P ABC-type enterochelin transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 OGLMJJLJ_01960 322159.STER_0956 1.71e-152 428.0 COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4IPIP@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 1 - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 OGLMJJLJ_01961 264199.stu0941 5.69e-186 516.0 COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,4HUI7@91061|Bacilli 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 OGLMJJLJ_01964 264199.stu0938 2.95e-104 301.0 COG4814@1|root,COG4814@2|Bacteria 2|Bacteria S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 OGLMJJLJ_01965 264199.stu0937 3.95e-24 91.3 COG4814@1|root,COG4814@2|Bacteria 2|Bacteria S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 OGLMJJLJ_01966 1046629.Ssal_01058 1.98e-10 60.1 COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes,4HEFQ@91061|Bacilli 91061|Bacilli S Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - AXE1,DLH,Peptidase_S15 OGLMJJLJ_01967 322159.STER_0949 4.6e-249 683.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli 91061|Bacilli E Dehydrogenase adhB - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N OGLMJJLJ_01968 322159.STER_0948 1.37e-267 731.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase OGLMJJLJ_01969 264199.stu0932 2.5e-202 561.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux OGLMJJLJ_01970 322159.STER_0946 2.69e-127 362.0 COG1309@1|root,COG1309@2|Bacteria,1TSUJ@1239|Firmicutes,4IPZN@91061|Bacilli 91061|Bacilli K Transcriptional regulator, TetR family - - - - - - - - - - - - TetR_C_8,TetR_N OGLMJJLJ_01971 888746.HMPREF9180_1259 9.28e-15 70.1 2DD3F@1|root,2ZGBB@2|Bacteria,1W4NX@1239|Firmicutes,4I0KR@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_01972 904306.HMPREF9192_1786 6.69e-143 408.0 COG1028@1|root,COG1028@2|Bacteria,1TRQB@1239|Firmicutes,4HAY3@91061|Bacilli 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short OGLMJJLJ_01973 1316408.HSISM1_519 9.06e-143 428.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli 91061|Bacilli V ABC transporter (Permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD OGLMJJLJ_01974 322159.STER_0003 7.84e-303 825.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_01975 435842.HMPREF0848_00743 4.13e-167 467.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli 91061|Bacilli H Belongs to the alpha-acetolactate decarboxylase family budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy OGLMJJLJ_01976 322159.STER_0940 0.0 1099.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N OGLMJJLJ_01977 1121864.OMO_01537 9.01e-75 244.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - MFS_1 OGLMJJLJ_01978 264199.stu0921 3.15e-175 488.0 COG0010@1|root,COG0010@2|Bacteria 2|Bacteria E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines speB - 3.5.3.11 ko:K01480 ko00330,ko01100,map00330,map01100 M00133 R01157 RC00024,RC00329 ko00000,ko00001,ko00002,ko01000 - - - Arginase OGLMJJLJ_01979 264199.stu0920 3.68e-271 743.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes 1239|Firmicutes C radical SAM domain protein nirJ - - ko:K06139,ko:K22227 - - - - ko00000 - - - Fer4_12,Fer4_14,Radical_SAM,SPASM OGLMJJLJ_01982 322159.STER_0934 7.95e-71 219.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HC2C@91061|Bacilli 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family - - - - - - - - - - - - HTH_3 OGLMJJLJ_01983 264199.stu0917 3.02e-74 229.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HC2C@91061|Bacilli 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family - - - - - - - - - - - - HTH_3 OGLMJJLJ_01984 264199.stu0916 3.63e-71 214.0 COG1813@1|root,COG1813@2|Bacteria 2|Bacteria K peptidyl-tyrosine sulfation - - - ko:K15773 - - - - ko00000,ko02048,ko03000 - - - HTH_3,HTH_31 OGLMJJLJ_01985 1408423.JHYA01000026_gene1200 0.000789 42.7 COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes,4H5UP@909932|Negativicutes 909932|Negativicutes S Toxin-antitoxin system, toxin component, RelE family - - - - - - - - - - - - Gp49 OGLMJJLJ_01988 264199.stu0911 0.0 1179.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C OGLMJJLJ_01990 1114965.Spaf_0915 5.84e-58 185.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli 91061|Bacilli IQ Acetoin reductase butA - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 OGLMJJLJ_01991 264199.stu0909 8.3e-67 204.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli 91061|Bacilli IQ Acetoin reductase butA - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 OGLMJJLJ_01992 322159.STER_0930 2.36e-61 188.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS pspE - - ko:K03972 - - - - ko00000 - - - Rhodanese OGLMJJLJ_01993 264199.stu0906 1.01e-99 289.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes 1239|Firmicutes F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK OGLMJJLJ_01994 904306.HMPREF9192_1810 5.45e-47 153.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase XK27_05470 - - - - - - - - - - - Meth_synt_2 OGLMJJLJ_01995 264199.stu0905 4.52e-99 292.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase XK27_05470 - - - - - - - - - - - Meth_synt_2 OGLMJJLJ_01996 322159.STER_0927 0.0 890.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA OGLMJJLJ_01997 264199.stu0902 0.0 868.0 COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,4HEWT@91061|Bacilli 91061|Bacilli T COG0642 Signal transduction histidine kinase - - 2.7.13.3 ko:K20487 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA OGLMJJLJ_01998 322159.STER_0925 1.9e-153 431.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes 1239|Firmicutes KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain spaR - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C OGLMJJLJ_01999 322159.STER_0924 6.19e-200 553.0 2DC01@1|root,2ZC51@2|Bacteria,1V2FW@1239|Firmicutes,4HG69@91061|Bacilli 91061|Bacilli S TraX protein - - - - - - - - - - - - TraX OGLMJJLJ_02000 322159.STER_0923 0.0 1348.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom OGLMJJLJ_02001 264199.stu0896 9.91e-204 563.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli 91061|Bacilli LU DNA protecting protein DprA dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A OGLMJJLJ_02002 322159.STER_0921 6.44e-90 270.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes 1239|Firmicutes GK ROK family - - - - - - - - - - - - ROK OGLMJJLJ_02003 322159.STER_0921 6.37e-110 323.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes 1239|Firmicutes GK ROK family - - - - - - - - - - - - ROK OGLMJJLJ_02004 322159.STER_0920 3.37e-174 486.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII OGLMJJLJ_02005 264199.stu0893 1.2e-202 561.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 OGLMJJLJ_02006 264199.stu0892 1.29e-165 462.0 COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1V758@1239|Firmicutes,4HIKZ@91061|Bacilli 91061|Bacilli K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_19,HTH_3,Peptidase_S24 OGLMJJLJ_02007 264199.stu0891 7.82e-118 337.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli 91061|Bacilli S small molecule binding protein (contains 3H domain) yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 OGLMJJLJ_02008 264199.stu0890 5.63e-113 326.0 2A1RE@1|root,311D4@2|Bacteria,1V4NF@1239|Firmicutes,4HH6C@91061|Bacilli 91061|Bacilli - - niaX GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - ECF-ribofla_trS OGLMJJLJ_02009 264199.stu0889 0.0 952.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB OGLMJJLJ_02010 264199.stu0888 9e-72 216.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 OGLMJJLJ_02011 322159.STER_0913 1.82e-162 455.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli 91061|Bacilli K transcriptional yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA OGLMJJLJ_02012 264199.stu0886 0.0 1037.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase OGLMJJLJ_02013 264199.stu0885 0.0 1229.0 COG2189@1|root,COG2189@2|Bacteria,1TR8A@1239|Firmicutes,4HBP1@91061|Bacilli 91061|Bacilli L Adenine specific DNA methylase Mod - - 2.1.1.72 ko:K07316 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase,TypeIII_RM_meth OGLMJJLJ_02014 264199.stu0884 0.0 1797.0 COG3421@1|root,COG3421@2|Bacteria,1TRVK@1239|Firmicutes,4HAVG@91061|Bacilli 91061|Bacilli S Type III restriction sthIR - 3.1.21.5 ko:K01156 - - - - ko00000,ko01000,ko02048 - - - ResIII OGLMJJLJ_02015 1116231.SMA_0980 2.47e-28 108.0 2DY2G@1|root,347TK@2|Bacteria,1W1ET@1239|Firmicutes,4HYVW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02017 904306.HMPREF9192_1827 8.31e-142 406.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli 91061|Bacilli C alcohol dehydrogenase adhP - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N OGLMJJLJ_02018 264199.stu0880 6.58e-81 239.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli 91061|Bacilli C alcohol dehydrogenase adhP - 1.1.1.1 ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N OGLMJJLJ_02019 435842.HMPREF0848_00769 2.18e-10 56.6 2E660@1|root,330UP@2|Bacteria,1VFJD@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_02020 264199.stu0879 4.66e-141 402.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH OGLMJJLJ_02021 904306.HMPREF9192_1830 3.92e-91 279.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH OGLMJJLJ_02022 322159.STER_0907 1.58e-202 560.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes 1239|Firmicutes ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 OGLMJJLJ_02023 264199.stu0876 7.2e-144 406.0 COG1126@1|root,COG1126@2|Bacteria 2|Bacteria E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran OGLMJJLJ_02024 264199.stu0875 2.37e-135 385.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 OGLMJJLJ_02025 322159.STER_0904 5.22e-75 224.0 COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli 91061|Bacilli P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon OGLMJJLJ_02026 322159.STER_0903 0.0 1159.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS OGLMJJLJ_02027 322159.STER_0901 8.86e-214 590.0 COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,4HC5J@91061|Bacilli 91061|Bacilli K Transcriptional regulator cpsY - - - - - - - - - - - HTH_1,LysR_substrate OGLMJJLJ_02028 264199.stu1454 2.27e-27 102.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_02029 904306.HMPREF9192_1840 2.64e-153 432.0 COG1705@1|root,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli 91061|Bacilli NU muramidase - - - ko:K02395,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM OGLMJJLJ_02030 322159.STER_0898 2.15e-217 602.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes 1239|Firmicutes S Membrane yeiH - - - - - - - - - - - Cons_hypoth698 OGLMJJLJ_02032 264199.stu0860 0.0 1016.0 COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZinT,ZnuA OGLMJJLJ_02033 264199.stu0859 1.82e-110 320.0 COG2339@1|root,COG2339@2|Bacteria 2|Bacteria D peptidase activity XK27_10720 - - - - - - - - - - - PrsW-protease OGLMJJLJ_02034 1046629.Ssal_00974 1.01e-70 225.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 OGLMJJLJ_02035 482234.SCAZ3_00400 0.0 896.0 2BVJW@1|root,32QXP@2|Bacteria,1UZVH@1239|Firmicutes,4HFK6@91061|Bacilli 91061|Bacilli S Uncharacterised protein family (UPF0236) - - - - - - - - - - - - UPF0236 OGLMJJLJ_02037 862969.SCI_0175 6.12e-13 70.9 2DP1C@1|root,3304N@2|Bacteria,1VHQA@1239|Firmicutes,4HPY6@91061|Bacilli,42DYE@671232|Streptococcus anginosus group 91061|Bacilli S Replication initiator protein A (RepA) N-terminus repA - - - - - - - - - - - RepA_N OGLMJJLJ_02038 997830.HMPREF1124_0868 3.93e-25 96.7 2DIZZ@1|root,304F3@2|Bacteria,1TWMJ@1239|Firmicutes,4I5FB@91061|Bacilli,43GKA@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02039 482234.SCAZ3_00380 6.65e-194 538.0 COG1192@1|root,COG1192@2|Bacteria 2|Bacteria D plasmid maintenance - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 OGLMJJLJ_02040 1035189.HMPREF9954_1815 2.87e-74 229.0 2DIZ3@1|root,304E1@2|Bacteria,1TWJM@1239|Firmicutes,4I5D6@91061|Bacilli,43GFK@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02041 1123311.KB904459_gene606 2.52e-315 859.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity - - - ko:K02395 - - - - ko00000,ko02035 - - - CHAP,Glucosaminidase,NLPC_P60,Rod-binding OGLMJJLJ_02042 997830.HMPREF1124_0864 5.23e-30 108.0 2DKPM@1|root,30A8D@2|Bacteria,1TWNB@1239|Firmicutes,4I5G5@91061|Bacilli,43GMF@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02043 482234.SCAZ3_00360 0.0 1296.0 COG0433@1|root,COG0433@2|Bacteria,1W186@1239|Firmicutes,4HA4T@91061|Bacilli 91061|Bacilli S COG0433 Predicted ATPase - - - - - - - - - - - - DUF87 OGLMJJLJ_02044 1035189.HMPREF9954_1819 4.92e-108 316.0 2DIYX@1|root,304DP@2|Bacteria,1TWJ2@1239|Firmicutes,4I5CJ@91061|Bacilli,43GDZ@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02046 1035189.HMPREF9954_1821 2.21e-35 122.0 2DIZK@1|root,304EN@2|Bacteria,1TWKS@1239|Firmicutes,4I5EI@91061|Bacilli,43GIZ@68892|Streptococcus infantis 91061|Bacilli S BRCA1 C Terminus (BRCT) domain - - - - - - - - - - - - BRCT OGLMJJLJ_02047 1035189.HMPREF9954_1822 1.27e-290 822.0 2DIYY@1|root,304DQ@2|Bacteria,1TWJ4@1239|Firmicutes,4I5CM@91061|Bacilli,43GE2@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02048 1035189.HMPREF9954_1823 5.41e-34 124.0 2DIZ9@1|root,304EA@2|Bacteria,1TWK4@1239|Firmicutes,4I5DS@91061|Bacilli,43GGZ@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02049 482234.SCAZ3_00330 0.0 2012.0 COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli 91061|Bacilli U COG3505 Type IV secretory pathway, VirD4 components - - - ko:K03205 ko03070,map03070 M00333 - - ko00000,ko00001,ko00002,ko02044 3.A.7 - - T4SS-DNA_transf OGLMJJLJ_02052 482234.SCAZ3_00315 3.62e-243 670.0 COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 3 family nagZ - 3.2.1.52 ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 M00628 R00022,R05963,R07809,R07810,R10831 RC00049 ko00000,ko00001,ko00002,ko01000 - - - DUF4309,Glyco_hydro_3 OGLMJJLJ_02053 482234.SCAZ3_00310 6.55e-97 282.0 COG0629@1|root,COG0629@2|Bacteria 2|Bacteria L single-stranded DNA binding - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB OGLMJJLJ_02054 482234.SCAZ3_00305 0.0 2551.0 COG3087@1|root,COG3087@2|Bacteria 2|Bacteria D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - Antigen_C,GbpC,Gram_pos_anchor,SPOR OGLMJJLJ_02055 585204.SMSK597_0526 2.43e-42 151.0 2DKEG@1|root,3099X@2|Bacteria,1U4P3@1239|Firmicutes,4IEEU@91061|Bacilli,2TQ3Q@28037|Streptococcus mitis 91061|Bacilli M LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor OGLMJJLJ_02056 1123311.KB904459_gene592 1.67e-251 691.0 2DCJK@1|root,2ZEEP@2|Bacteria,1W5ZH@1239|Firmicutes,4I1YG@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02057 1035189.HMPREF9954_1835 5.62e-45 148.0 2DIZG@1|root,304EJ@2|Bacteria,1TWKN@1239|Firmicutes,4I5EE@91061|Bacilli,43GIM@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02058 482234.SCAZ3_00280 0.0 1154.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli 91061|Bacilli O Belongs to the ClpA ClpB family - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small OGLMJJLJ_02059 482234.SCAZ3_00275 0.0 1131.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HBQF@91061|Bacilli 91061|Bacilli L Topoisomerase IA topA2 - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim OGLMJJLJ_02061 482234.SCAZ3_00265 0.0 3317.0 COG0358@1|root,COG2856@1|root,COG0358@2|Bacteria,COG2856@2|Bacteria,1UICF@1239|Firmicutes,4ISNE@91061|Bacilli 91061|Bacilli EL Toprim-like - - - - - - - - - - - - DUF3991,Toprim_2 OGLMJJLJ_02063 482234.SCAZ3_00255 0.0 1467.0 COG2255@1|root,COG2255@2|Bacteria,1V0DS@1239|Firmicutes,4HENV@91061|Bacilli 91061|Bacilli L four-way junction helicase activity - - - - - - - - - - - - - OGLMJJLJ_02064 997830.HMPREF1124_0841 8.86e-52 168.0 2DIZQ@1|root,304EU@2|Bacteria,1TWM2@1239|Firmicutes,4I5EW@91061|Bacilli,43GJQ@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02065 1123315.AUIP01000012_gene1974 2.45e-181 505.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK7D@91061|Bacilli 91061|Bacilli F DNA/RNA non-specific endonuclease - - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 OGLMJJLJ_02066 1035189.HMPREF9954_1854 6.04e-50 161.0 2DIZJ@1|root,304EM@2|Bacteria,1TWKR@1239|Firmicutes,4I5EH@91061|Bacilli,43GIX@68892|Streptococcus infantis 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - - OGLMJJLJ_02067 997830.HMPREF1124_0837 1.25e-28 106.0 29P5X@1|root,30A42@2|Bacteria,1TWM0@1239|Firmicutes,4I5ET@91061|Bacilli,43GJG@68892|Streptococcus infantis 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - - OGLMJJLJ_02070 1035189.HMPREF9954_1858 1.59e-127 375.0 2DCHT@1|root,2ZE7E@2|Bacteria,1W27X@1239|Firmicutes,4I25E@91061|Bacilli,43GGG@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02073 997830.HMPREF1124_0832 1.12e-20 83.6 2DJ0H@1|root,304FT@2|Bacteria,1TWNW@1239|Firmicutes,4I5GQ@91061|Bacilli,43GN8@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02075 997830.HMPREF1124_0830 1.31e-52 169.0 2DIZ5@1|root,304E3@2|Bacteria,1TWJQ@1239|Firmicutes,4I5D8@91061|Bacilli,43GFN@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02076 1035189.HMPREF9954_1862 1.81e-20 83.2 2DJ09@1|root,304FH@2|Bacteria,1TWN4@1239|Firmicutes,4I5FY@91061|Bacilli,43GM5@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02078 1123315.AUIP01000012_gene1984 0.0 962.0 COG1959@1|root,COG1959@2|Bacteria,1UBUD@1239|Firmicutes,4HB0A@91061|Bacilli 91061|Bacilli K Primase C terminal 1 (PriCT-1) repE - - - - - - - - - - - PriCT_1 OGLMJJLJ_02080 1123312.KB904580_gene880 3.39e-155 436.0 COG1451@1|root,COG1451@2|Bacteria,1VCK6@1239|Firmicutes,4HGVM@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2786) - - - - - - - - - - - - DUF2786 OGLMJJLJ_02082 997830.HMPREF1124_0825 6.36e-66 205.0 2BKU4@1|root,32FAD@2|Bacteria,1TWKB@1239|Firmicutes,4I5E1@91061|Bacilli,43GHI@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02084 1069533.Sinf_0805 1.56e-38 129.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_02085 1116231.SMA_0321 1.14e-231 639.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_02086 272623.L172704 2.17e-76 231.0 2FHJA@1|root,349D7@2|Bacteria,1W16R@1239|Firmicutes,4HYIT@91061|Bacilli,1YCF5@1357|Lactococcus 91061|Bacilli S Uncharacterised lipoprotein family - - - - - - - - - - - - Lipoprotein_22 OGLMJJLJ_02087 272623.L173469 1.31e-97 285.0 COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,4HK1B@91061|Bacilli,1YCDJ@1357|Lactococcus 91061|Bacilli T TspO/MBR family tspO - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR OGLMJJLJ_02088 1046629.Ssal_00974 6.4e-55 184.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 OGLMJJLJ_02089 904306.HMPREF9192_1264 2.01e-129 379.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 OGLMJJLJ_02090 264199.stu0833 3.43e-207 574.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N OGLMJJLJ_02091 322159.STER_0876 3.04e-232 639.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 OGLMJJLJ_02092 264199.stu0831 1.2e-208 577.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 OGLMJJLJ_02093 322159.STER_0874 3.64e-174 486.0 COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli 91061|Bacilli S cyclic nucleotide-binding protein yejC - - - - - - - - - - - DUF1003 OGLMJJLJ_02094 1046629.Ssal_00969 5.24e-22 94.7 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - DUF4297,PhageMin_Tail OGLMJJLJ_02095 322159.STER_0367 1.46e-282 772.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_02096 322159.STER_0891 8.27e-195 542.0 COG4975@1|root,COG4975@2|Bacteria,1TQBN@1239|Firmicutes,4HAVH@91061|Bacilli 91061|Bacilli U Glucose uptake glcU GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - ko:K05340 - - - - ko00000,ko02000 2.A.7.5 - - Sugar_transport OGLMJJLJ_02097 264199.stu0852 2.89e-121 347.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase OGLMJJLJ_02098 264199.stu0851 4.67e-73 219.0 COG0732@1|root,COG0732@2|Bacteria 2|Bacteria V type I restriction modification DNA specificity domain hsdS - 2.1.1.72,3.1.21.3 ko:K01154,ko:K07317 - - - - ko00000,ko01000,ko02048 - - - DDE_Tnp_1,Methylase_S OGLMJJLJ_02099 1116231.SMA_0321 6.35e-244 670.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_02100 264199.stu0828 2.72e-122 348.0 COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli 91061|Bacilli S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF OGLMJJLJ_02101 264199.stu0827 7.17e-172 479.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM OGLMJJLJ_02102 264199.stu0826 1.17e-105 304.0 COG0720@1|root,COG0720@2|Bacteria,1V9HU@1239|Firmicutes,4HJEX@91061|Bacilli 91061|Bacilli H synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS OGLMJJLJ_02103 322159.STER_0869 2.62e-159 446.0 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC OGLMJJLJ_02104 264199.stu0824 1.84e-83 246.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli 91061|Bacilli J endoribonuclease L-PSP aldR - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP OGLMJJLJ_02105 264199.stu0822 3.04e-40 135.0 COG3464@1|root,COG3464@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_02106 1046629.Ssal_00208 1.2e-68 218.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_02108 264199.stu0818 0.0 905.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli 91061|Bacilli J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon OGLMJJLJ_02109 264199.stu0817 1.83e-277 759.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 OGLMJJLJ_02110 322159.STER_0862 1.32e-106 308.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY OGLMJJLJ_02111 904306.HMPREF9192_1246 0.0 1499.0 COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII OGLMJJLJ_02112 264199.stu0812 5.3e-156 437.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B OGLMJJLJ_02113 264199.stu0811 2.35e-217 601.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 OGLMJJLJ_02114 322159.STER_0858 9.61e-247 678.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family mglC - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 OGLMJJLJ_02115 322159.STER_0857 0.0 967.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli 91061|Bacilli S ABC transporter, ATP-binding protein mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran OGLMJJLJ_02116 322159.STER_0856 6.01e-246 676.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HANH@91061|Bacilli 91061|Bacilli S ABC-type transport system, periplasmic component surface lipoprotein tcsA - - ko:K02058,ko:K07335 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - Bmp OGLMJJLJ_02117 264199.stu0807 4.51e-75 224.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 OGLMJJLJ_02118 264199.stu0806 6.29e-82 243.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - iSB619.SA_RS00835 DeoC OGLMJJLJ_02119 1046629.Ssal_00948 7.07e-40 137.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - iSB619.SA_RS00835 DeoC OGLMJJLJ_02120 435842.HMPREF0848_00806 1.43e-116 346.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli 91061|Bacilli F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C OGLMJJLJ_02121 264199.stu0802 2.16e-32 112.0 COG0213@1|root,COG0213@2|Bacteria 2|Bacteria F phosphorylase activity pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C OGLMJJLJ_02122 1046629.Ssal_00947 2.18e-32 122.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli 91061|Bacilli F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C OGLMJJLJ_02123 322159.STER_0852 1.86e-135 384.0 COG2813@1|root,COG2813@2|Bacteria,1V3JX@1239|Firmicutes,4IR00@91061|Bacilli 91061|Bacilli J Methyltransferase small domain protein rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS OGLMJJLJ_02124 264199.stu0799 1.43e-221 610.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK OGLMJJLJ_02125 322159.STER_0850 1.15e-39 132.0 COG0268@1|root,COG0268@2|Bacteria 2|Bacteria J rRNA binding rpsT GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p OGLMJJLJ_02126 264199.stu0796 1.53e-212 586.0 COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes 1239|Firmicutes L integrase core domain - - - ko:K07497 - - - - ko00000 - - - HTH_21,rve,rve_2 OGLMJJLJ_02127 264199.stu0797 4.58e-156 439.0 COG2963@1|root,COG2963@2|Bacteria,1V2T5@1239|Firmicutes,4HFZ1@91061|Bacilli 91061|Bacilli L Transposase - - - - - - - - - - - - HTH_28,HTH_Tnp_1 OGLMJJLJ_02128 264199.stu0795 2.72e-156 439.0 COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli 91061|Bacilli T Histidine kinase ciaH - 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA OGLMJJLJ_02129 904306.HMPREF9192_1234 1.29e-52 178.0 COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli 91061|Bacilli T Histidine kinase ciaH - 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA OGLMJJLJ_02130 904306.HMPREF9192_1234 7.49e-37 135.0 COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli 91061|Bacilli T Histidine kinase ciaH - 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA OGLMJJLJ_02131 904306.HMPREF9192_1233 1.33e-151 427.0 COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli 91061|Bacilli T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ciaR - - ko:K14983 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C OGLMJJLJ_02132 322159.STER_0837 0.0 1089.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS OGLMJJLJ_02133 264199.stu0790 3.82e-157 441.0 COG0452@1|root,COG0452@2|Bacteria,1V7YG@1239|Firmicutes,4HMIF@91061|Bacilli 91061|Bacilli H Phosphopantothenate-cysteine ligase coaB - 6.3.2.5 ko:K21977 ko00770,map00770 M00120 R04231 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - DFP OGLMJJLJ_02134 264199.stu0789 3.51e-119 342.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein OGLMJJLJ_02135 264199.stu0788 2.62e-121 347.0 COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,4HFPD@91061|Bacilli 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt OGLMJJLJ_02136 322159.STER_0833 0.0 1111.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli 91061|Bacilli G Phosphoglucomutase pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV OGLMJJLJ_02137 264199.stu0786 1.26e-210 582.0 COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,4HGHI@91061|Bacilli 91061|Bacilli C reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR OGLMJJLJ_02138 264199.stu0785 0.0 1478.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 OGLMJJLJ_02140 264199.stu0771 0.0 1142.0 COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HBKC@91061|Bacilli 91061|Bacilli EH component I pabB - 2.6.1.85,4.1.3.38 ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 - R01716,R05553 RC00010,RC01418,RC01843,RC02148 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4,Chorismate_bind OGLMJJLJ_02141 264199.stu0770 0.0 1640.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli 91061|Bacilli P cation transport ATPase - - 3.6.3.2,3.6.3.6,3.6.3.8 ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.2,3.A.3.3,3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 OGLMJJLJ_02142 435842.HMPREF0848_01320 2.03e-52 168.0 COG2963@1|root,COG2963@2|Bacteria,1VDX9@1239|Firmicutes,4HRT2@91061|Bacilli 91061|Bacilli L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_02143 264199.stu0036 9.35e-14 67.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_21,HTH_28,HTH_Tnp_1,rve OGLMJJLJ_02144 264199.stu1787 3.03e-75 226.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes 1239|Firmicutes L Integrase core domain protein - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 OGLMJJLJ_02145 322159.STER_0805 1.42e-307 838.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD OGLMJJLJ_02146 264199.stu0763 7.07e-48 153.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli 91061|Bacilli IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding OGLMJJLJ_02147 264199.stu0762 6.93e-300 818.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli 91061|Bacilli M Membrane protein involved in D-alanine export dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT OGLMJJLJ_02148 264199.stu0761 0.0 1020.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C OGLMJJLJ_02149 1000570.HMPREF9966_1459 1.41e-14 67.4 2DIU2@1|root,3044G@2|Bacteria,1TW0K@1239|Firmicutes,4I4PC@91061|Bacilli,42EHI@671232|Streptococcus anginosus group 91061|Bacilli S D-Ala-teichoic acid biosynthesis protein - - - - - - - - - - - - DUF3687 OGLMJJLJ_02150 322159.STER_0800 0.0 1097.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HCVN@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein XK27_10035 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_02151 322159.STER_0799 0.0 1076.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein yfiB1 - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran OGLMJJLJ_02152 264199.stu0757 8.92e-137 388.0 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity pvaA - - ko:K02395 - - - - ko00000,ko02035 - - - Lysozyme_like,SLT_2 OGLMJJLJ_02153 264199.stu0756 5e-227 626.0 COG3081@1|root,COG3081@2|Bacteria,1V437@1239|Firmicutes,4IQXJ@91061|Bacilli 91061|Bacilli S 37-kD nucleoid-associated bacterial protein - - - - - - - - - - - - NA37 OGLMJJLJ_02154 322159.STER_0796 2.06e-297 811.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT OGLMJJLJ_02155 264199.stu0754 1.46e-141 399.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC OGLMJJLJ_02156 322159.STER_0794 4.33e-197 546.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS OGLMJJLJ_02157 264199.stu0752 9.23e-247 679.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 OGLMJJLJ_02158 264199.stu0751 2.55e-143 404.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK OGLMJJLJ_02159 264199.stu0750 6.18e-238 654.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase OGLMJJLJ_02160 322159.STER_0790 4.53e-196 542.0 COG0625@1|root,COG0625@2|Bacteria,1TPZ7@1239|Firmicutes,4HD0K@91061|Bacilli 91061|Bacilli O Glutathione S-transferase gst - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_2 OGLMJJLJ_02161 264199.stu0748 2.9e-225 620.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli 91061|Bacilli S domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 OGLMJJLJ_02162 264199.stu0747 1.27e-222 613.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HDFE@91061|Bacilli 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE OGLMJJLJ_02163 264199.stu0746 1.39e-61 188.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli 91061|Bacilli J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 OGLMJJLJ_02164 322159.STER_0786 3.14e-294 804.0 COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli 91061|Bacilli P Mn2 and Fe2 transporters of the NRAMP family mntH_2 - - - - - - - - - - - Nramp OGLMJJLJ_02165 264199.stu0741 0.0 1855.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS OGLMJJLJ_02166 322159.STER_0782 3.44e-185 517.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HJYN@91061|Bacilli 91061|Bacilli D Cell division protein DivIVA divIVA - - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA OGLMJJLJ_02167 264199.stu0739 6.84e-184 512.0 COG2302@1|root,COG2302@2|Bacteria 2|Bacteria T S4 RNA-binding domain ylmH - - ko:K02487,ko:K06596 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko01001,ko02022,ko02035 - - - S4 OGLMJJLJ_02168 322159.STER_0780 1.8e-46 150.0 COG0762@1|root,COG0762@2|Bacteria 2|Bacteria D integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT OGLMJJLJ_02169 322159.STER_0779 1.79e-125 358.0 COG1799@1|root,COG1799@2|Bacteria 2|Bacteria D cell septum assembly sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF OGLMJJLJ_02170 264199.stu0736 1.62e-158 444.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N OGLMJJLJ_02171 264199.stu0735 1.08e-302 827.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin OGLMJJLJ_02172 264199.stu0734 0.0 875.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA OGLMJJLJ_02173 264199.stu0733 1.59e-234 649.0 COG1589@1|root,COG1589@2|Bacteria,1VHEY@1239|Firmicutes 1239|Firmicutes D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 OGLMJJLJ_02174 264199.stu0732 1.56e-257 706.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 OGLMJJLJ_02175 264199.stu0731 0.0 874.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M OGLMJJLJ_02176 663952.SDD27957_07710 2.68e-12 63.9 2DJ77@1|root,304WT@2|Bacteria,1TXC0@1239|Firmicutes,4I69V@91061|Bacilli,1M9RX@119603|Streptococcus dysgalactiae group 91061|Bacilli S Protein of unknown function (DUF3165) - - - - - - - - - - - - DUF3165 OGLMJJLJ_02177 264199.stu0729 0.0 1187.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 OGLMJJLJ_02178 264199.stu0728 1.61e-226 624.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK OGLMJJLJ_02179 264199.stu0727 1.58e-37 126.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli 91061|Bacilli S protein conserved in bacteria yqgQ - - - - - - - - - - - DUF910 OGLMJJLJ_02180 322159.STER_0768 1.13e-102 296.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR OGLMJJLJ_02181 322159.STER_0767 2.72e-119 341.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin OGLMJJLJ_02182 322159.STER_0767 1.91e-119 341.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin OGLMJJLJ_02183 264199.stu0722 4.5e-150 422.0 COG1989@1|root,COG1989@2|Bacteria,1V91J@1239|Firmicutes 1239|Firmicutes NOU Bacterial Peptidase A24 N-terminal domain pppA - 3.4.23.43 ko:K02236 - M00429 - - ko00000,ko00002,ko01000,ko02044 - - - DiS_P_DiS,Peptidase_A24 OGLMJJLJ_02184 322159.STER_0765 1.04e-289 796.0 COG2367@1|root,COG2367@2|Bacteria,1VHF8@1239|Firmicutes,4HU1N@91061|Bacilli 91061|Bacilli V D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Beta-lactamase2 OGLMJJLJ_02185 1046629.Ssal_00039 1.41e-88 270.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_02186 322159.STER_0151 3.74e-187 526.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_02187 322159.STER_0762 6.73e-145 408.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli 91061|Bacilli C radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0005575,GO:0005576 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N OGLMJJLJ_02188 264199.stu0719 3.3e-237 653.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta OGLMJJLJ_02189 322159.STER_0760 0.0 1811.0 COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli 91061|Bacilli H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase OGLMJJLJ_02190 1046629.Ssal_01392 2.18e-73 221.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 OGLMJJLJ_02191 264199.stu0716 8.61e-97 283.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt OGLMJJLJ_02192 904306.HMPREF9192_1176 1.63e-187 524.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 OGLMJJLJ_02193 322159.STER_0756 5.35e-121 346.0 COG1704@1|root,COG1704@2|Bacteria,1V1G7@1239|Firmicutes,4IR1J@91061|Bacilli 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA OGLMJJLJ_02194 904306.HMPREF9192_1174 1.73e-223 618.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK9Z@91061|Bacilli 91061|Bacilli F DNA RNA non-specific endonuclease spd - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 OGLMJJLJ_02195 1046629.Ssal_01404 1.47e-116 339.0 COG5464@1|root,COG5464@2|Bacteria 2|Bacteria S double-stranded DNA endodeoxyribonuclease activity - - - - - - - - - - - - PDDEXK_2 OGLMJJLJ_02196 435842.HMPREF0848_00367 6.76e-63 200.0 COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli 91061|Bacilli S PD-(D/E)XK nuclease family transposase - - - - - - - - - - - - PDDEXK_2 OGLMJJLJ_02197 904306.HMPREF9192_1172 0.0 1043.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase OGLMJJLJ_02198 322159.STER_0752 9.35e-174 485.0 COG2852@1|root,COG2852@2|Bacteria,1V2TW@1239|Firmicutes,4HHGA@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria - - - - - - - - - - - - - OGLMJJLJ_02199 904306.HMPREF9192_1168 4.22e-136 385.0 299SU@1|root,2ZWV2@2|Bacteria,1W2YW@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_02200 264199.stu0708 2.34e-155 451.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4HFAV@91061|Bacilli 91061|Bacilli V type I restriction modification DNA specificity domain protein hsdS - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S OGLMJJLJ_02201 1123304.AQYA01000035_gene1027 1.81e-277 787.0 COG4694@1|root,COG4694@2|Bacteria,1TT67@1239|Firmicutes,4HCP2@91061|Bacilli 91061|Bacilli S AAA domain - - - - - - - - - - - - AAA_13 OGLMJJLJ_02202 322159.STER_0747 0.0 1937.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli 91061|Bacilli L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII OGLMJJLJ_02203 435842.HMPREF0848_00357 1.79e-90 270.0 COG4221@1|root,COG4221@2|Bacteria,1V08N@1239|Firmicutes,4IPTJ@91061|Bacilli 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family sdh - - - - - - - - - - - adh_short OGLMJJLJ_02204 264199.stu0704 1.26e-61 195.0 COG4221@1|root,COG4221@2|Bacteria,1V08N@1239|Firmicutes,4IPTJ@91061|Bacilli 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family sdh - - - - - - - - - - - adh_short OGLMJJLJ_02205 904306.HMPREF9192_1160 6.03e-22 93.2 COG1073@1|root,COG1073@2|Bacteria,1VEWD@1239|Firmicutes,4IQU0@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 OGLMJJLJ_02206 1046629.Ssal_01417 1.3e-45 157.0 COG1073@1|root,COG1073@2|Bacteria,1VEWD@1239|Firmicutes,4IQU0@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 OGLMJJLJ_02207 904306.HMPREF9192_1160 4.51e-14 70.5 COG1073@1|root,COG1073@2|Bacteria,1VEWD@1239|Firmicutes,4IQU0@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 OGLMJJLJ_02208 264199.stu0701 6.94e-146 411.0 COG2141@1|root,COG2141@2|Bacteria,1VJRB@1239|Firmicutes,4ISN7@91061|Bacilli 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - - OGLMJJLJ_02209 1123304.AQYA01000028_gene1720 1.14e-35 126.0 COG2461@1|root,COG2461@2|Bacteria 2|Bacteria P Hemerythrin HHE cation binding domain protein - - - - - - - - - - - - PAS_10 OGLMJJLJ_02210 264199.stu0699 1.99e-196 548.0 COG3757@1|root,COG3757@2|Bacteria,1V2YH@1239|Firmicutes,4HI8U@91061|Bacilli 91061|Bacilli M Glycosyl hydrolase, family 25 - - 3.5.1.28 ko:K01447,ko:K07273 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Glyco_hydro_25 OGLMJJLJ_02211 264199.stu0698 2.49e-105 304.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HIH1@91061|Bacilli 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit OGLMJJLJ_02212 264199.stu0697 1.45e-149 421.0 COG0406@1|root,COG0406@2|Bacteria,1V7EZ@1239|Firmicutes,4HJCK@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase pgm - - - - - - - - - - - His_Phos_1 OGLMJJLJ_02213 264199.stu0696 6.05e-220 606.0 COG1011@1|root,COG1011@2|Bacteria,1V5P7@1239|Firmicutes,4HHGY@91061|Bacilli 91061|Bacilli S hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 OGLMJJLJ_02214 904293.HMPREF9176_0571 7.92e-29 109.0 2BXK6@1|root,33WGZ@2|Bacteria,1VVCA@1239|Firmicutes,4HWEI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02215 322159.STER_0734 1.44e-75 239.0 COG1388@1|root,COG1388@2|Bacteria,1VWTU@1239|Firmicutes,4HX18@91061|Bacilli 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM OGLMJJLJ_02216 322159.STER_0734 5.37e-20 87.8 COG1388@1|root,COG1388@2|Bacteria,1VWTU@1239|Firmicutes,4HX18@91061|Bacilli 91061|Bacilli M LysM domain - - - - - - - - - - - - LysM OGLMJJLJ_02217 264199.stu0692 0.0 981.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon OGLMJJLJ_02218 264199.stu1086 4e-143 412.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_02219 1116231.SMA_1382 9.84e-281 767.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_02220 491916.RHECIAT_PC0000880 1.95e-85 268.0 COG0318@1|root,COG0318@2|Bacteria,1N5JR@1224|Proteobacteria,2VGXQ@28211|Alphaproteobacteria,4BNNM@82115|Rhizobiaceae 28211|Alphaproteobacteria IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - - OGLMJJLJ_02221 264199.stu1389 1.57e-136 387.0 COG1280@1|root,COG1280@2|Bacteria,1TRUX@1239|Firmicutes,4HFB2@91061|Bacilli 91061|Bacilli E LysE type translocator - - - - - - - - - - - - LysE OGLMJJLJ_02222 322159.STER_0151 2.12e-212 592.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07485 - - - - ko00000 - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_02223 1046629.Ssal_00039 1.24e-62 202.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 OGLMJJLJ_02225 322159.STER_0729 4.49e-297 813.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp OGLMJJLJ_02226 264199.stu0676 2.97e-45 145.0 COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli 91061|Bacilli S protein conserved in bacteria XK27_12190 - - - - - - - - - - - PC4 OGLMJJLJ_02228 322159.STER_0726 6.28e-112 323.0 COG1268@1|root,COG1268@2|Bacteria,1VA1G@1239|Firmicutes,4HNE8@91061|Bacilli 91061|Bacilli S biotin synthase bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY OGLMJJLJ_02229 322159.STER_0725 0.0 875.0 COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli 91061|Bacilli O Peptidase U32 yrrO - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C OGLMJJLJ_02230 264199.stu0671 4.13e-227 625.0 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 OGLMJJLJ_02232 322159.STER_0722 4.75e-91 267.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli 91061|Bacilli S General stress protein ytxH - - - - - - - - - - - YtxH OGLMJJLJ_02233 322159.STER_0721 1.14e-26 103.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 OGLMJJLJ_02234 264199.stu0667 6.15e-190 527.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT OGLMJJLJ_02235 322159.STER_0719 2.26e-215 595.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N OGLMJJLJ_02236 264199.stu0665 4.88e-54 169.0 COG1983@1|root,COG1983@2|Bacteria,1VF0M@1239|Firmicutes,4IRAN@91061|Bacilli 91061|Bacilli KT PspC domain WQ51_05770 - - - - - - - - - - - PspC OGLMJJLJ_02237 322159.STER_0716 0.0 1332.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli 91061|Bacilli K Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF OGLMJJLJ_02239 322159.STER_0714 1.69e-201 559.0 COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli 91061|Bacilli S permease XK27_03015 - - ko:K07089 - - - - ko00000 - - - ArsP_1 OGLMJJLJ_02240 322159.STER_0713 1.14e-189 527.0 COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HGMG@91061|Bacilli 91061|Bacilli S TIGR03943 family XK27_03010 - - ko:K08986 - - - - ko00000 - - - DUF1980 OGLMJJLJ_02241 322159.STER_0712 5.2e-253 694.0 2DZ2B@1|root,34C6V@2|Bacteria,1W43F@1239|Firmicutes 1239|Firmicutes S CRISPR-associated protein Csn2 subfamily St - - - - - - - - - - - - Cas_St_Csn2 OGLMJJLJ_02242 322159.STER_0711 2.94e-71 214.0 COG3512@1|root,COG3512@2|Bacteria 2|Bacteria L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas2 - - ko:K09951 - - - - ko00000,ko02048 - - - CRISPR_Cas2 OGLMJJLJ_02243 264199.stu0658 6.55e-221 608.0 COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,4HC5E@91061|Bacilli 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette cas1 - - ko:K15342 - - - - ko00000,ko02048,ko03400 - - - Cas_Cas1 OGLMJJLJ_02244 322159.STER_0709 0.0 2068.0 COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,4HE0R@91061|Bacilli 91061|Bacilli L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer cas9 - - ko:K09952 - - - - ko00000,ko01000,ko02048 - - - Cas9_REC,HNH_4 OGLMJJLJ_02245 1046629.Ssal_01451 3.1e-124 356.0 2F636@1|root,33YMH@2|Bacteria,1VYAW@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_02246 1046629.Ssal_01453 7.87e-36 126.0 COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 OGLMJJLJ_02247 1046629.Ssal_01454 3.24e-40 138.0 COG1266@1|root,COG1266@2|Bacteria,1VBYM@1239|Firmicutes,4HM2K@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi OGLMJJLJ_02248 1046629.Ssal_01454 7.8e-35 124.0 COG1266@1|root,COG1266@2|Bacteria,1VBYM@1239|Firmicutes,4HM2K@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi OGLMJJLJ_02249 1046629.Ssal_01455 3.71e-46 149.0 2FBVV@1|root,3440F@2|Bacteria,1VZAT@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - OGLMJJLJ_02251 1046629.Ssal_01457 4.98e-85 250.0 2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli 91061|Bacilli S Pyrimidine dimer DNA glycosylase yqeB - - - - - - - - - - - Pyr_excise OGLMJJLJ_02252 435842.HMPREF0848_00317 3.12e-77 231.0 COG3272@1|root,COG3272@2|Bacteria,1VGGK@1239|Firmicutes,4HP7S@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722 OGLMJJLJ_02254 272623.L0432 1.06e-198 550.0 COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,4HDK4@91061|Bacilli 91061|Bacilli L COG2801 Transposase and inactivated derivatives tra981A - - ko:K07497 - - - - ko00000 - - - HTH_21,rve OGLMJJLJ_02255 1069533.Sinf_0805 3.6e-51 162.0 COG2963@1|root,COG2963@2|Bacteria 2|Bacteria L transposase activity - - - ko:K07483 - - - - ko00000 - - - HTH_Tnp_1 OGLMJJLJ_02256 264199.stu1036 3.03e-247 679.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli 91061|Bacilli L Transposase B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut OGLMJJLJ_02257 638301.HMPREF0444_1312 5.56e-124 354.0 2DBDH@1|root,2Z8KQ@2|Bacteria,1V2YZ@1239|Firmicutes,4HK4W@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02258 638301.HMPREF0444_1318 2.4e-71 218.0 COG1670@1|root,COG1670@2|Bacteria,1V1G4@1239|Firmicutes,4HI02@91061|Bacilli,27HT6@186828|Carnobacteriaceae 91061|Bacilli J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 OGLMJJLJ_02259 1046629.Ssal_01495 0.0 876.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr OGLMJJLJ_02260 322159.STER_0701 2.48e-124 354.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity mip - - - - - - - - - - - CMD OGLMJJLJ_02261 322159.STER_0700 5.22e-255 699.0 COG1960@1|root,COG1960@2|Bacteria,1UYHK@1239|Firmicutes,4HCT5@91061|Bacilli 91061|Bacilli I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_N OGLMJJLJ_02262 1069533.Sinf_0933 2.35e-198 552.0 COG1275@1|root,COG1275@2|Bacteria 2|Bacteria P C4-dicarboxylate transporter malic acid transport protein ydiA - - ko:K03304,ko:K11041 ko05150,map05150 - - - ko00000,ko00001,ko02000,ko02042 2.A.16,2.A.16.1 - - DUF2723,SLAC1 OGLMJJLJ_02263 322159.STER_0698 0.0 870.0 COG1316@1|root,COG1316@2|Bacteria,1TSWQ@1239|Firmicutes,4HE66@91061|Bacilli 91061|Bacilli K Transcriptional regulator msrR - - - - - - - - - - - LytR_cpsA_psr OGLMJJLJ_02264 264199.stu0647 8.09e-196 543.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT OGLMJJLJ_02265 322159.STER_0696 7.63e-112 321.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI OGLMJJLJ_02266 264199.stu0645 2.41e-297 812.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase OGLMJJLJ_02267 264199.stu0644 1.88e-222 613.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli 91061|Bacilli C Belongs to the LDH MDH superfamily hicD2 - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N OGLMJJLJ_02268 264199.stu0643 1.48e-71 215.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HPJM@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family XK26_04240 - - - - - - - - - - - Com_YlbF OGLMJJLJ_02269 322159.STER_0692 1.58e-263 722.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH OGLMJJLJ_02270 264199.stu0641 1.29e-279 764.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt OGLMJJLJ_02271 322159.STER_0690 8.37e-257 704.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase OGLMJJLJ_02272 322159.STER_0689 5.74e-206 569.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N OGLMJJLJ_02273 322159.STER_0688 8.04e-158 442.0 COG0710@1|root,COG0710@2|Bacteria,1VHVX@1239|Firmicutes,4IPJP@91061|Bacilli 91061|Bacilli E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate aroD - 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I OGLMJJLJ_02274 264199.stu0637 1.45e-280 766.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM OGLMJJLJ_02275 264199.stu0636 0.0 1402.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli 91061|Bacilli M Belongs to the LTA synthase family ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase OGLMJJLJ_02276 322159.STER_0685 1.83e-33 115.0 2FKS5@1|root,34CCP@2|Bacteria,1W67C@1239|Firmicutes 1239|Firmicutes - - WQ51_00785 - - - - - - - - - - - - OGLMJJLJ_02282 1069533.Sinf_0802 6.8e-144 412.0 COG0791@1|root,COG0791@2|Bacteria,1VT9V@1239|Firmicutes,4HV77@91061|Bacilli 91061|Bacilli M Bacteriophage peptidoglycan hydrolase - - - - - - - - - - - - Amidase_5 OGLMJJLJ_02283 888049.HMPREF8578_0250 1.67e-30 109.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli 91061|Bacilli S COG5546 Small integral membrane protein hol - - - - - - - - - - - Phage_holin_1 OGLMJJLJ_02286 562981.HMPREF0428_01807 5.02e-05 48.1 2DJ9C@1|root,3053M@2|Bacteria,1TXN5@1239|Firmicutes,4I6NG@91061|Bacilli,3WFRD@539002|Bacillales incertae sedis 91061|Bacilli S Protein of unknown function (DUF1366) - - - - - - - - - - - - DUF1366 OGLMJJLJ_02287 112023.Q9MCJ5_9CAUD 0.0 1056.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0098021 - - - - - - - - - - - OGLMJJLJ_02288 306323.Q56S86_9CAUD 0.0 1622.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - OGLMJJLJ_02289 78541.O80180_9CAUD 4.9e-211 601.0 4QBF8@10239|Viruses,4QUS7@35237|dsDNA viruses no RNA stage,4QPI9@28883|Caudovirales,4QKN2@10699|Siphoviridae 10699|Siphoviridae S Phage tail protein - - - - - - - - - - - - - OGLMJJLJ_02290 85154.O34071_BPO12 0.0 1127.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 - - - - - - - - - - - OGLMJJLJ_02292 682370.C9W9I6_9CAUD 2.32e-75 225.0 4QBPH@10239|Viruses,4QV0G@35237|dsDNA viruses no RNA stage,4QQHY@28883|Caudovirales,4QKQD@10699|Siphoviridae 10699|Siphoviridae S Pfam:Phage_TAC_12 - - - - - - - - - - - - - OGLMJJLJ_02293 1385385.U6E9D4_9CAUD 1.74e-97 285.0 4QAVQ@10239|Viruses,4QXUP@35237|dsDNA viruses no RNA stage,4QPGB@28883|Caudovirales,4QKPR@10699|Siphoviridae 10699|Siphoviridae S Phage major tail protein 2 - - - - - - - - - - - - - OGLMJJLJ_02294 306323.Q56S92_9CAUD 1.69e-80 239.0 4QB3I@10239|Viruses,4QPE3@28883|Caudovirales,4QKP4@10699|Siphoviridae 10699|Siphoviridae - - - GO:0005575,GO:0008150,GO:0016032,GO:0019012,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0044423,GO:0051704,GO:0098003,GO:0098004,GO:0098015 - - - - - - - - - - - OGLMJJLJ_02295 682370.C9W9I3_9CAUD 1.19e-57 180.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - OGLMJJLJ_02297 1123302.KB904182_gene68 9.52e-49 158.0 2EKJJ@1|root,33E9D@2|Bacteria,1VN9C@1239|Firmicutes 1239|Firmicutes S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 OGLMJJLJ_02299 1385385.U6E9B4_9CAUD 1.04e-226 627.0 4QB9S@10239|Viruses,4QUXK@35237|dsDNA viruses no RNA stage,4QPW1@28883|Caudovirales,4QM6J@10699|Siphoviridae 10699|Siphoviridae S Phage major capsid protein E - GO:0005575,GO:0019012,GO:0019028,GO:0019030,GO:0039620,GO:0044423 - - - - - - - - - - - OGLMJJLJ_02301 1123315.AUIP01000003_gene242 7.08e-32 121.0 2DS40@1|root,33EEI@2|Bacteria,1VNT5@1239|Firmicutes,4HRSQ@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4355) - - - - - - - - - - - - DUF4355 OGLMJJLJ_02302 1385385.U6E9F1_9CAUD 3.15e-140 404.0 4QC5Z@10239|Viruses,4QUNP@35237|dsDNA viruses no RNA stage,4QPGX@28883|Caudovirales,4QKMB@10699|Siphoviridae 10699|Siphoviridae S Phage Mu protein F like protein - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0046729 - - - - - - - - - - - OGLMJJLJ_02303 682370.C9W9H5_9CAUD 0.0 869.0 4QAR7@10239|Viruses,4QUW5@35237|dsDNA viruses no RNA stage,4QPKJ@28883|Caudovirales,4QKQ3@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein, SPP1 Gp6-like - GO:0005575,GO:0019012,GO:0019028,GO:0032991,GO:0044423,GO:0046729,GO:0046798 - - - - - - - - - - - OGLMJJLJ_02304 73422.L0P509_9CAUD 2.73e-304 828.0 4QMEV@10699|Siphoviridae 10699|Siphoviridae S Terminase-like family - - - - - - - - - - - - - OGLMJJLJ_02305 1054460.SPPN_00130 8.82e-30 113.0 COG3728@1|root,COG3728@2|Bacteria 2|Bacteria L DNA packaging - - - ko:K07474 - - - - ko00000 - - - Terminase_2 OGLMJJLJ_02306 173707.Q938L8_9CAUD 4.27e-41 140.0 4QDP9@10239|Viruses,4QWR2@35237|dsDNA viruses no RNA stage,4QQY8@28883|Caudovirales,4QMYB@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - OGLMJJLJ_02309 1461246.X2KPG8_9VIRU 1.48e-30 114.0 4QAXV@10239|Viruses 10239|Viruses S YopX protein - - - - - - - - - - - - - OGLMJJLJ_02311 73422.L0P3M1_9CAUD 2.46e-33 122.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales 28883|Caudovirales S protein disulfide oxidoreductase activity - - - - - - - - - - - - - OGLMJJLJ_02312 768726.HMPREF9178_1077 7.8e-39 137.0 2DKDX@1|root,3098Q@2|Bacteria,1U4MH@1239|Firmicutes,4I04V@91061|Bacilli,2TQ21@28037|Streptococcus mitis 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 OGLMJJLJ_02314 1123315.AUIP01000014_gene1938 1.69e-39 140.0 2DS9F@1|root,33F4A@2|Bacteria,1VMJG@1239|Firmicutes,4HSZ4@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 OGLMJJLJ_02317 1123309.AQYB01000014_gene918 1.5e-15 70.1 2BK0S@1|root,32EDT@2|Bacteria,1TZGK@1239|Firmicutes,4HSJ1@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02319 112023.Q9MCM0_9CAUD 5.46e-102 295.0 4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - OGLMJJLJ_02320 646413.C5IUI2_9CAUD 2.22e-83 248.0 4QAU9@10239|Viruses,4QVR2@35237|dsDNA viruses no RNA stage,4QQV4@28883|Caudovirales,4QKUJ@10699|Siphoviridae 10699|Siphoviridae S Single-strand binding protein family - - - - - - - - - - - - - OGLMJJLJ_02321 1239381.K4JU67_9CAUD 2.47e-60 203.0 4QB3F@10239|Viruses,4QV3C@35237|dsDNA viruses no RNA stage,4QPZ0@28883|Caudovirales,4QM6P@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF1351) - - - - - - - - - - - - - OGLMJJLJ_02322 35344.A0A097PBE8_BPT12 3.03e-40 144.0 4QBFR@10239|Viruses,4QV1E@35237|dsDNA viruses no RNA stage,4QPRX@28883|Caudovirales,4QNJQ@10744|Podoviridae 10744|Podoviridae S ERF superfamily - - - - - - - - - - - - - OGLMJJLJ_02324 633135.C9WB96_9CAUD 1.93e-171 480.0 4QBU2@10239|Viruses,4QV13@35237|dsDNA viruses no RNA stage,4QPH3@28883|Caudovirales,4QM65@10699|Siphoviridae 10699|Siphoviridae S IstB-like ATP binding protein - - - - - - - - - - - - - OGLMJJLJ_02325 1035184.HMPREF1042_1642 3.91e-110 326.0 COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,4HMRU@91061|Bacilli,42EBW@671232|Streptococcus anginosus group 91061|Bacilli L N-terminal phage replisome organiser (Phage_rep_org_N) - - - - - - - - - - - - DnaB_2,Phage_rep_org_N,Phg_2220_C OGLMJJLJ_02329 1069533.Sinf_0769 1.99e-34 120.0 2ENNN@1|root,33GA0@2|Bacteria,1VN2K@1239|Firmicutes,4HR9I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - OGLMJJLJ_02331 646413.C5IUM1_9CAUD 2.69e-176 496.0 4QAPQ@10239|Viruses,4QZ6P@35237|dsDNA viruses no RNA stage,4QPWV@28883|Caudovirales,4QMUB@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - OGLMJJLJ_02332 64186.O21995_9CAUD 1.54e-38 129.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010944,GO:0016032,GO:0019012,GO:0019042,GO:0019044,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043900,GO:0043902,GO:0043903,GO:0044212,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0046782,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0050434,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - OGLMJJLJ_02333 64186.O21993_9CAUD 1.58e-68 208.0 4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010944,GO:0016032,GO:0019012,GO:0019042,GO:0019044,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043900,GO:0043902,GO:0043903,GO:0044212,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0046782,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0050434,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - OGLMJJLJ_02334 173707.Q938N7_9CAUD 2.44e-19 84.3 4QFPY@10239|Viruses,4QX5A@35237|dsDNA viruses no RNA stage,4QPUR@28883|Caudovirales,4QKSN@10699|Siphoviridae 10699|Siphoviridae S Pfam:Peptidase_M78 - - - - - - - - - - - - - OGLMJJLJ_02335 1385385.U6E9C7_9CAUD 1.93e-49 162.0 4QBN1@10239|Viruses,4QZ19@35237|dsDNA viruses no RNA stage,4QQWW@28883|Caudovirales,4QKN7@10699|Siphoviridae 10699|Siphoviridae S Host cell surface-exposed lipoprotein - - - - - - - - - - - - - OGLMJJLJ_02336 646413.C5IUL7_9CAUD 4.9e-266 730.0 4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses no RNA stage,4QPDM@28883|Caudovirales,4QKN9@10699|Siphoviridae 10699|Siphoviridae S Phage integrase family - GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - - - - - - - - - - - OGLMJJLJ_02342 1069533.Sinf_0802 6.8e-144 412.0 COG0791@1|root,COG0791@2|Bacteria,1VT9V@1239|Firmicutes,4HV77@91061|Bacilli 91061|Bacilli M Bacteriophage peptidoglycan hydrolase - - - - - - - - - - - - Amidase_5 OGLMJJLJ_02343 888049.HMPREF8578_0250 1.67e-30 109.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli 91061|Bacilli S COG5546 Small integral membrane protein hol - - - - - - - - - - - Phage_holin_1 OGLMJJLJ_02346 562981.HMPREF0428_01807 5.02e-05 48.1 2DJ9C@1|root,3053M@2|Bacteria,1TXN5@1239|Firmicutes,4I6NG@91061|Bacilli,3WFRD@539002|Bacillales incertae sedis 91061|Bacilli S Protein of unknown function (DUF1366) - - - - - - - - - - - - DUF1366 OGLMJJLJ_02347 112023.Q9MCJ5_9CAUD 0.0 1056.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales 28883|Caudovirales S N-acetylmuramoyl-L-alanine amidase activity - GO:0005575,GO:0019012,GO:0019028,GO:0044423,GO:0098021 - - - - - - - - - - - OGLMJJLJ_02348 112023.Q9MCJ6_9CAUD 2.24e-38 141.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - ## 2057 queries scanned ## Total time (seconds): 3.3943281173706055 ## Rate: 606.01 q/s