LOCUS       c00116_gnlPro..        12349 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LOJFJKPI_116.
ACCESSION   c00116_gnlPro..
VERSION     c00116_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 06:18:01
            Original ID  :: gnl|Prokka|LOJFJKPI_116
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12349
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12349
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[738:10930]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      739..10930
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..12349
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12349
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             248..625
                     /locus_tag="ctg116_1"
                     /transl_table=11
                     /translation="MKQSLKYGLFLVLALLIHVVSNEAMEDNCRVAPPTYRQEKCYVSQ
                     DHPVHNALERLHYFYSTQSCDMSHADVAHVPTDKSVQLLITYFREYKSQQNTSQTHSLH
                     IPKYFYDPITYYIYGLRKIVI"
     CDS             739..1089
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_2"
                     /sec_met_domain="Oxidored_q4 (E-value: 4.2e-38, bitscore:
                     119.3, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFTFLVVVLLTALAFVGVVIALSRAISPRSYNVQKFEAYECGIP
                     TRGKSWMQFRVGYYLFAILFLMFDVETAFLFPWAVVMHDMGPQGLVSILFFFIILVLGL
                     AYAWRKGALEWK"
     CDS             1080..1673
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_3"
                     /sec_met_domain="Oxidored_q6 (E-value: 2.1e-26, bitscore:
                     82.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEITKKPKIKSIPYDEFIDNESLEKLVKELNTGGANVFLGVLDDL
                     VNWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITN
                     KMAPVLKRLYDQMPDPKYVVAVGGCAVSGGPFKKSYHVLNGVDKILPVDVYIPGCPPRP
                     EAFYYGMMQLQRKVKIEKFFGGTNRKEKKPEFMK"
     CDS             1670..3286
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_4"
                     /sec_met_domain="Complex1_30kDa (E-value: 4.8e-37,
                     bitscore: 117.0, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 4e-65, bitscore:
                     209.2, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNEERRIMQEIQFIVPAALHDEMLRLRNEKQMDFLESLTGMDWG
                     VADEKDAPEKLRGLGVVYHLESTITGERIALKTAVTDRERPEIPSVSDIWKIADFYERE
                     VFDYYGIVFVGHPDMRRLYLRNDWVGYPMRKDNDPEKDNPLCMANEETFDTTQEIELNP
                     DGTIKNREMKLFGEEEYVVNIGPQHPATHGVMRFRVSLEGEIIRKIDANCGYIHRGIEK
                     MNESLTYPQTLALTDRLDYLGAHQNRHALCMCIEKAMGIEVSDRVKYIRTIMDELQRID
                     SHLLFYSALAMDLGALTDFFYGFRDREKILDIFEETCGGRLIMNYNTIGGVQADLHPNF
                     VKRVKEFIPYMRGIIHEYHDIFTGNIIAQSRMKGVGVLSREDAISFGCTGGTGRASGWA
                     CDVRKRIPYGVYDKVDFQEIVYTEGDCFARYLVRMDEIMESLKIIEQLIDNIPEGPYQE
                     KMKPIIRVPEGSYYAAVEGSRGEFGVFLESQGDKMPYRLHYRATGLPLVAAIDTICRGA
                     KIADLIAIGGTLDYVVPDIDR"
     CDS             3412..4488
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_5"
                     /sec_met_domain="NADHdh (E-value: 3.6e-123, bitscore:
                     400.3, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTNWIHELLLSVMPEGWAIFIECIAVGVCIVALYAILAI
                     VLIYMERKVCGFFQCRLGPNRVGKWGSIQVICDVLKMLTKEIFTPKDADRFLYNLAPFM
                     VIIASFLTFACIPFNKGAEILNFNVGVFFLLAASSIGVVGILLAGWGSNNKFSLIGAMR
                     SGAQIISYELSVGMSIMTMVVLMGTMQFSEIVEGQADGWFIFKGHIPAVIAFIIYLIAG
                     NAECNRGPFDLPEAESELTAGYHTEYSGMHFGFFYLAEYLNLFIVASVAATIFLGGWMP
                     LHIVGLDGFNAVMDYIPGFIWFFAKAFFVVFLLMWIKWTFPRLRIDQILNLEWKYLVPI
                     SMVNLLLMACCVAFGFHF"
     CDS             4466..4987
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-13, bitscore: 40.8,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.8e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPLASTSKIRIMEYKDQKYTYLGGLIHGISTLATGMKTSIKVYFR
                     KKVTEQYPENRKELKMFDRFRGTLAMPHNENNEHRCVACGLCQIACPNDTITVTSETIE
                     TEDGKKKKILAKYEYDLGACMFCQLCVNACPHDAITFDQNFEHAVFDRTKLVLQLNHAG
                     SKVIEKKKEV"
     CDS             4990..5502
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_7"
                     /sec_met_domain="Oxidored_q3 (E-value: 5.2e-37, bitscore:
                     116.4, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTLETVVFYFLAAFIIAMSIMTVTTQRIVRSATYLLFVLFGTA
                     GIYFLLGYTFLGSVQIMVYAGGIVVLYVFSILLTSGEGDRAEKLKRSRFLAGLFTMVAG
                     LAIILFITLKHNFLQTTNLVPLEINIHTIGNALLSSDKYGYILPFEAISILLLACIIGG
                     IMIARKR"
     CDS             5598..5906
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_8"
                     /sec_met_domain="Oxidored_q2 (E-value: 2.5e-22, bitscore:
                     68.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHMEYYLVVSTIMMFAGIYGFFTRRNTLAILISVELMLNATDIN
                     FAVFNRFLFPGGMEGYFFALFSIAISAAETAIAIAIMINIYRNLRSIQVRNLDDLKW"
     CDS             5994..7883
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_9"
                     /sec_met_domain="Proton_antipo_N (E-value: 1.4e-25,
                     bitscore: 79.0, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 3.4e-87,
                     bitscore: 282.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTILILLLPFLSFLILGIGGKWMSHRTAGAIGTLILGAVVVLS
                     YVTAFQYFSAPRLEDGTFATLIPYNFTWLPFTETLRFDLGILLDPISVMMLIVISTVSL
                     MVHIYSFGYMKGETGFQRYYAFLSLFTMSMLGLVVATNIFQMYLFWELVGVSSYLLIGF
                     YYTKPAAIAASKKAFIVTRFADLGFLIGILIYGYYGGTFGFTPDTVSLISGGASMLPLA
                     LGLMFIGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIAYA
                     PDTLHMIAWVGAFTAFYAASVACVQSDIKRVLAFSTISQIGFMMVALGVCTSMDPHHGG
                     LGYMASMFHLFTHAMFKALLFLGAGSIIHAVHSNEMSAMGGLRKYMPITHWTFLIACLA
                     IAGIPPFSGFFSKDEILAACFQYSPAMGWVMTVIAAMTAFYMFRLYYGIFWGKENKELH
                     AHHTPHESPLAMTFPLMFLAVVTCLAGFIPFGHFISSNGESYSIHLDLSVAVTSVVIAI
                     ISIGIATWMYKNAKQPVANALAKRFNGLWTAAYHRFYIDDIYQFITHKIIFRCISTPIA
                     WFDRHVVDGFFNFLAWATNTTSDEIRGLQSGQVQQYAYVFLCGALALILLLVL"
     CDS             7966..9450
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_10"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.5e-68,
                     bitscore: 220.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSIFVLIPLLMLAGLWAARGIKAIRGVMVTGASALLIASVVL
                     TFMYLGERSAGNTAEMLFRADTLWYAPLHISYSVGVDGISVAMLLLSAVIVFTGTFASW
                     RLQPLTKEYFLWFTLLSMGVFGFFISIDLFTMFMFYEIALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIYFGSGATTMNLLEIAQLHNIPFAQQCIWFPLTFLGFGV
                     LGALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRIAMYLMPEAANELSWIFLI
                     LTGISVVYGAFSACVQTDLKYINAYSSVSHCGLVLFAILMLNQTAATGAILQMLSHGLM
                     TALFFALIGMIYGRTHTRDVRELTGLMKVMPFLSVCYVIAGLANLGLPGLSGFIAEMTI
                     FVGSFQNNDVFHRTLTIIACSSIVITAVYILRLVGKILYGTCTNKHHLALTDATWDERV
                     AVICLIVCVAGLGMAPFWVSHMIGESVLPVVSQLIP"
     CDS             9488..10930
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg116_11"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.4e-72,
                     bitscore: 234.0, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYSQFLHMREELSLVAVLLLLFLADLFMSPDAHKQKGTRPVLNT
                     MLPVILMAIHTAINLVPGTAADIFGGMYHYVPMHTVVKSILNIGTLIVFLMAHEWMKRD
                     DTSFKQGEFYVLTLSTLFGMYLMISAGHFLMFFIGLETASIPMAALIAFDKYRHNSAEA
                     GAKYILTALFSSALLLFGLSMIYGSAGTLYFDDLPAHIDGNPLQIMAFVFFFTGMAFKL
                     SLVPFHLWTADVYEGAPSTVTAYLSVISKGSAAFVLMAILIKVFAPMIHDWQEVLYWVT
                     IASITIANIFAIRQQNLKRLMAFSSISQAGYIMLGVIGGTTQGMTAMVYYILVYAAANL
                     GVFAVITIVALRSQKFTLEDYAGLYKTNPKMAFLMTISLFSLAGIPPFAGFFSKFFIFM
                     AAFEAGFHLLVFIALVNTVISLYYYLLIVKAMYITPSDNPIPTFRSDRCTKWGLALCTL
                     GIIGLGIASIVYQSIDKLSFGI"
     CDS             complement(10980..12347)
                     /locus_tag="ctg116_12"
                     /transl_table=11
                     /translation="KQDVIGVNFFENPNVPQHIRDRVRDEDLVDFRLNYSFERAEGYYH
                     PDRRDTIDIYTKVSKLYDNEGNFNGYILISIDNTEQIDAMNRIRDFENFFLLISDYAKV
                     GYAKLNLLNRKGYAIKQWYKNLGEEEDTPLADVVGVYRNMHPEDRERIFDFYREVRKGN
                     RKHFQGEMRICRPGKKNEWNWIRMNVVVTTYNPEENEVEIIGINYDITELKETEKELIL
                     ARDKAEMMDRLKSAFLANMSHEIRTPLNAIVGFSDLLVDTENIEERREYIQIVKENNDL
                     LLQLISDILDLSKIEAGTFEFTNGDVDVNMLCEDIVRSMQMKVKENVELMFDPHLAECR
                     IISDRNRLHQVISNFVNNAIKFTSEGSIRVGYKQKGEELEFYVQDTGVGIDAESQAHIF
                     ERFVKLNSFVHGTGLGLSICQSIVEQMGGKIGVESEPGKGSRFWFSLPCFVVMSEE"
ORIGIN
        1 tatatctaat tctgcaaaag aatgaaattt ctctgagtaa tcagaaaaaa gcaacataaa
       61 tcattggttt cattacatct tttaaccaaa tataaattct tgcatacgta attggaaagt
      121 tagattaaaa aacatagctt aaaaaacaaa actataagca agcaagttaa aaaatacttt
      181 tttgtaaccc cgactttgca aaaaacatga atattaatcc tatatttgca gccgttaaaa
      241 gaggaagatg aaacaaagct taaaatacgg actatttctg gtacttgctt tgctgatcca
      301 tgttgtttct aatgaagcaa tggaagataa ctgcagagta gcccccccga catatcgcca
      361 ggagaagtgc tacgtatctc aggatcatcc tgttcataat gctcttgaac gtcttcatta
      421 tttctattct acccagtctt gtgatatgag tcacgcggat gttgcacacg tgcctacaga
      481 taaaagcgtg caattgctga ttacttattt ccgtgaatac aaaagccagc aaaacacgtc
      541 tcagactcat tcactccata ttcccaagta cttttacgat cctattacat attatatata
      601 tggtttaagg aagatcgtca tttagacggt acaatccatt atcttattcg tcaattcatt
      661 acagttggtt tcatccgggt gtggagaaac taattgttta tttctatata atattcaatc
      721 taaacagcta ttgaaattat gaattttaca tttttagttg ttgttttact gacagcgctc
      781 gcttttgtcg gtgtagtaat agccctttca cgagctattt caccacgttc gtacaatgta
      841 caaaagtttg aagcttatga atgtggtata ccaacgcgtg gtaaatcatg gatgcagttc
      901 cgtgtaggtt actacctgtt tgccatcctg ttcctgatgt tcgacgtgga aacagctttt
      961 ctgttccctt gggcagtagt aatgcatgac atgggacctc aggggctcgt tagtattctc
     1021 ttcttcttta ttattttggt tctgggcctt gcttatgcct ggaggaaagg agctttggaa
     1081 tggaaataac caaaaaaccg aaaataaaat caattccgta tgatgagttc atcgacaatg
     1141 agtcattgga aaagttggtc aaggaactta ataccggagg agcgaacgtt tttcttgggg
     1201 ttctggacga ccttgtcaac tggggacgca gcaattcact gtggccgctt actttcgcaa
     1261 ccagctgttg cggcatcgaa ttcatggcac tgggtgccgc gcgttatgat atggcccgct
     1321 tcgggttcga agtagcacgt gccagtccgc gccaagctga tatgatcatg gtctgcggaa
     1381 caatcaccaa caagatggca ccggtactga aacgtttgta cgatcagatg cccgatccga
     1441 aatatgtagt tgccgtaggc ggatgtgctg tcagcggagg gcctttcaag aagtcttatc
     1501 atgtgctgaa tggagtagat aagattcttc cggtcgatgt atatatcccc ggatgtccgc
     1561 cccgcccgga agctttctat tacggcatga tgcaactaca acgcaaagtg aaaatagaga
     1621 aattctttgg tggaacgaac agaaaagaga agaaaccgga atttatgaaa tgaagaatga
     1681 ggaacgaaga attatgcaag aaatacaatt tatagtccct gcagcgttac acgacgaaat
     1741 gctgcgcttg cgaaatgaaa aacagatgga cttccttgaa agcctcactg gtatggactg
     1801 gggagtagca gacgaaaaag acgcaccgga gaaactccgt ggtttaggcg ttgtctacca
     1861 tctggaatcg actattacgg gagaacggat agcactgaaa acagccgtta ccgaccgtga
     1921 acgaccagaa attccgtcag tcagcgatat atggaaaata gccgacttct acgaacgtga
     1981 agtgttcgac tactatggca ttgttttcgt agggcatccc gatatgcgcc gcctttactt
     2041 acgtaatgac tgggtaggat accccatgcg taaagataat gatccggaga aagataatcc
     2101 gctttgtatg gctaacgaag agacgttcga tacaacacag gaaatagaac ttaatccgga
     2161 cggaacgatt aaaaacagag aaatgaaact ctttggagaa gaagagtatg tagtcaacat
     2221 tggcccgcaa caccctgcaa ctcacggtgt aatgcgcttc cgcgtttctc ttgaaggtga
     2281 aattattcgt aagatcgatg ctaactgcgg ttatatccat cggggtatcg agaaaatgaa
     2341 cgagagtctt acatatccgc agacattggc attgactgac cgcctcgact atctgggcgc
     2401 acatcagaac cgtcacgctt tgtgtatgtg catcgagaaa gcgatgggca tcgaagtgag
     2461 cgaccgtgtc aaatacattc gtacaattat ggatgagctg caacgtatcg actctcactt
     2521 actgttctac tccgccctcg ccatggacct tggagcactg actgatttct tctacggatt
     2581 ccgtgaccgt gaaaagattc tcgatatttt tgaagagact tgcggcggac gtctgatcat
     2641 gaactacaat accatcggtg gtgtacaggc cgaccttcat cctaacttcg tcaagcgggt
     2701 aaaagaattt atcccttata tgagaggtat cattcacgaa taccacgaca tatttaccgg
     2761 caacattatc gctcagagcc gtatgaaggg cgtcggagtg ttaagccgtg aagatgcaat
     2821 ctcattcggt tgcaccgggg gtacaggccg tgcttcgggc tgggcttgcg atgtacgtaa
     2881 gcggataccg tacggtgtat atgacaaggt agacttccag gaaattgttt atacggaagg
     2941 agactgtttc gcccgttatc tggtacgtat ggacgaaatc atggagagtc tgaagattat
     3001 agagcagttg atagacaaca ttcccgaagg cccgtatcag gaaaagatga aaccgatcat
     3061 ccgcgttccc gaaggcagtt attatgccgc cgtagaagga agccgcggag aattcggagt
     3121 ctttctcgaa agtcagggtg acaagatgcc ttatcgcctg cactatcgtg ctacgggatt
     3181 gccacttgtt gctgcaatcg acacgatttg ccgcggagcg aaaattgccg acttgattgc
     3241 catcggagga acactggact atgtagttcc ggacatcgac cgataaacaa gagataaaaa
     3301 acaagtatta agtataaagt agtaagtatt aaccgactat gcaatatgat atacgctata
     3361 ttccgcatgg aattaatact taatacttaa aacctaataa ttaaaatata tatgttcgac
     3421 tttagtatag taacaaactg gatacatgag ctgctgctct ccgttatgcc ggagggatgg
     3481 gccatcttta tagagtgcat agctgtcggc gtgtgcatcg ttgcactata tgctattctg
     3541 gctatcgtac tgatttacat ggaacgcaaa gtctgtggtt tcttccagtg ccgcctcggt
     3601 ccgaaccgtg tcggtaaatg gggttctatt caagtgatat gcgacgtact caagatgctg
     3661 accaaggaga ttttcactcc gaaggatgcc gaccgcttcc tctacaatct ggctccattc
     3721 atggtaatta tcgcctcgtt cctcactttc gcttgtattc cttttaataa aggagcggaa
     3781 attctgaatt ttaatgtggg cgtattcttc ctgctggctg cttccagcat cggtgtggta
     3841 ggtattctgc ttgccggttg gggtagtaac aacaagtttt cgctgatcgg tgccatgcga
     3901 agcggcgcac agatcatcag ttatgagttg tcagtgggta tgagcatcat gacgatggtc
     3961 gtactgatgg gcaccatgca gttctccgaa atcgtagaag gacaggctga cggatggttt
     4021 atcttcaaag gacatattcc tgccgttatc gctttcatca tctatctcat tgccggaaat
     4081 gcagaatgta accgtggccc gttcgacctt cccgaagcgg aaagtgaatt gacggccgga
     4141 tatcatacgg aatattccgg tatgcacttc ggtttctttt atctggcgga atatctgaat
     4201 ctgtttatcg tagccagcgt ggccgctacc atctttttgg gaggctggat gccattgcat
     4261 atcgtcggtt tggacggatt caacgctgtt atggactata ttcccggctt catctggttc
     4321 tttgccaaag cattcttcgt tgtgttcctc ttaatgtgga tcaaatggac tttcccacgc
     4381 ctgcgtatcg accagattct gaatctggaa tggaaatatc tggttccaat ttctatggta
     4441 aacctattat taatggcatg ttgtgttgcc tttggcttcc acttctaaaa taagaattat
     4501 ggaatataaa gatcaaaaat atacgtactt gggaggactg atacatggta tcagcactct
     4561 ggcaacgggt atgaaaacca gtatcaaggt atacttccgt aagaaggtaa ccgaacagta
     4621 tcctgaaaac cggaaagagc tgaaaatgtt cgaccggttc cgtggtacac tggcaatgcc
     4681 ccacaatgag aataacgaac accgctgtgt agcctgcgga ttgtgtcaga tagcttgtcc
     4741 gaacgataca atcaccgtaa ccagcgaaac gatcgagact gaagacggca agaagaagaa
     4801 aatcctggca aaatatgaat atgacctcgg agcttgtatg ttctgccaac tgtgtgtcaa
     4861 cgcttgtccg catgacgcca tcacgttcga ccagaacttc gaacatgccg tctttgaccg
     4921 gacgaagctt gttctgcaac tgaatcatgc cggtagtaaa gtaattgaaa agaaaaaaga
     4981 agtttagata tgggatcaac acttgaaaca gtagtattct actttttggc agcatttatt
     5041 attgcaatgt ccatcatgac ggtgactacc caacgtattg tccgctcagc cacctatctg
     5101 ctcttcgtgc tcttcggcac ggctggcatc tatttcctgc tgggttacac atttctgggg
     5161 tctgtccaga ttatggttta tgccggtggt atcgtcgttc tttatgtatt ctccatcctg
     5221 ctgaccagtg gagaaggtga tcgcgccgag aaactgaaac gaagcaggtt tctggcagga
     5281 ctctttacga tggttgccgg tttagcgatt atcttgttta tcaccctgaa gcataacttc
     5341 ctgcaaacga ccaacctggt tccgctggaa ataaacatcc acaccattgg taatgcttta
     5401 ttaagcagtg acaaatatgg ttatatattg cctttcgaag caatcagtat tttattgctg
     5461 gcttgtatca tcggtggtat catgatcgcc cgaaagagat aaataagtaa gtattaacta
     5521 ttaagtatca ggtattaggc tgcgcaatga atcgcaagga attaatactt attacttaaa
     5581 acctaataat ttcagatatg atacacatgg aatattatct ggtagtttct accatcatga
     5641 tgtttgcagg aatctatggg ttctttaccc gccgtaatac gctggctatc ctgatttctg
     5701 tagagttaat gctgaacgcc acggacatca acttcgccgt gttcaaccgt tttctctttc
     5761 cgggaggcat ggaaggctat ttctttgcac tcttttccat cgctatttcg gctgcggaaa
     5821 cggctatagc tatcgccatc atgattaaca tttaccgcaa cctccgaagc attcaagtcc
     5881 gcaatctgga cgatctgaag tggtagtgcc aaagcggcac gacccaattt ccattcggat
     5941 ggatatcgtg ataaatatga acaataataa aacaagtaat taaaataaac tgtatggaac
     6001 taacaattct aatactcctt cttcccttcc tctccttcct cattctggga atcggaggaa
     6061 aatggatgtc tcatcggaca gcaggtgcta tcggtacgct gatactggga gcagtagtag
     6121 tactatcgta cgttacggct ttccaatatt tctccgcccc tcgtttggaa gacggaacat
     6181 ttgccacatt gataccttat aattttacgt ggcttccttt caccgagact ttacgatttg
     6241 atctgggcat tctgctagat cctatatccg tgatgatgct gattgtcatt tctaccgtgt
     6301 cactgatggt gcatatctac tccttcggct acatgaaagg tgagacgggc tttcaacgtt
     6361 attacgcttt cctgtccctg tttacaatgt ctatgctggg actggtggtt gccacaaaca
     6421 ttttccagat gtatcttttc tgggaactgg tgggtgtcag ttcttatctg ctgatcggtt
     6481 tttactatac aaagcctgct gccattgccg cttccaagaa agcgttcatt gtcacccgct
     6541 ttgcagactt aggcttcctt atcggtattc tgatttacgg atactacggt ggcacattcg
     6601 gcttcacacc ggatacggta tcattgatca gtggcggcgc ttccatgctt ccattggctt
     6661 tgggactgat gtttatcggt ggcgccggaa agagtgccat gttcccgttg catatctggc
     6721 tgcccgatgc catggaaggt cctactcctg tcagtgcctt gatccatgcg gctacgatgg
     6781 tagttgccgg cgtttatctg gtagcgcgta tgttcccgct tttcattgct tatgcaccgg
     6841 acaccttaca tatgattgcc tgggtaggtg ctttcaccgc cttttatgca gcaagcgtgg
     6901 cttgcgtaca atcggatatc aaacgtgtgc tggccttctc gaccatttca cagattggtt
     6961 ttatgatggt agcactgggc gtttgtactt ctatggaccc gcaccacgga ggactgggat
     7021 atatggcttc catgttccac ctcttcacac acgccatgtt taaggcatta ctcttcttgg
     7081 gtgccggcag cattatccat gcagtacatt ccaacgaaat gtcagccatg ggaggactac
     7141 gcaaatacat gcctattact cactggacat tcctgattgc ctgtctcgcc attgccggta
     7201 ttcctccgtt ctccggtttc ttctcaaaag atgagatttt ggctgcctgc ttccaatata
     7261 gccctgcaat gggttgggtg atgacagtaa tcgccgcaat gaccgccttc tatatgttcc
     7321 gcctctacta cggcatcttc tggggcaaag aaaataaaga gcttcatgct catcacaccc
     7381 cgcatgagag tccgttggct atgacttttc cgttgatgtt tctggcggtt gttacctgcc
     7441 ttgcagggtt cattcctttc ggacacttta tcagttcgaa cggggagtct tactctattc
     7501 acctcgatct gtcggtagct gtcacaagcg ttgtaattgc gattatttct atcgggattg
     7561 ccacatggat gtataagaat gccaaacagc ctgttgccaa tgcacttgcc aaacggttca
     7621 atggattgtg gacagctgct tatcatcgtt tttatattga tgatatatac cagtttatta
     7681 cgcataagat catcttccgt tgcatttcga ctcctatcgc atggttcgac cgtcatgtag
     7741 tggatggatt ctttaatttc ctggcatggg ctacgaatac gacaagcgac gagatacgtg
     7801 gtcttcaaag cggtcaggta cagcaatacg catacgtgtt cctttgcgga gcgctggcgc
     7861 ttatcctgct gttagttcta tagcaagtat taactatcag gtattagata ttaagctgcg
     7921 caacaagtcg ctgcgaatta atacttaaaa cttaataatt caattatgaa ttttttatca
     7981 atcttcgtac tcatcccctt actgatgctt gccggacttt gggcagcacg gggaatcaaa
     8041 gcgattcggg gggttatggt taccggcgca tcggcacttc tgattgcctc cgtcgtactt
     8101 acctttatgt atttgggaga acgcagtgcc ggcaacacgg cagaaatgct attccgtgcg
     8161 gatacactct ggtatgcacc gcttcacatc tcctactcgg taggcgttga cggtatttcg
     8221 gtagccatgt tgttattgtc tgccgttatt gtattcacag gtactttcgc ctcctggcgt
     8281 ctgcagcctc tgacaaaaga atatttcctt tggttcacac tgttgtctat gggagtcttc
     8341 ggattcttta tatccattga cttattcacc atgttcatgt tctacgaaat cgcgctgatt
     8401 cctatgtacc tgctgatcgg tgtatggggt tcgggacgta aagaatatgc agccatgaag
     8461 ctgaccctta tgctgatggg cggttccgct ttcctgctga tcggtattct cggaatctat
     8521 ttcggttcgg gagctaccac catgaacctg ctggaaatag cacagctaca taatattcct
     8581 tttgcacagc aatgtatctg gttcccgctt accttcctcg ggttcggtgt gctgggtgct
     8641 cttttcccgt tccacacatg gagtcccgat ggtcacgctt ccgccccgac agctgtatcc
     8701 atgcttcacg ccggagtact gatgaaactg ggaggttacg gatgtttccg tatcgccatg
     8761 tatctgatgc cggaagccgc taacgaactt tcatggatat tcctgatact gacaggtatc
     8821 tccgttgttt acggagcatt ctccgcttgc gtacagacag acttgaaata catcaacgct
     8881 tactcttccg tttctcactg cggactggta cttttcgcca ttctgatgct gaatcagact
     8941 gctgcgacag gagccattct tcagatgctt tcccacggat tgatgacagc cttgttcttt
     9001 gccctgatcg gtatgattta tggacgtaca cacacacgtg atgtccgcga gcttaccgga
     9061 ttaatgaaag taatgccgtt cctcagcgta tgttatgtga ttgccggtct tgccaatctc
     9121 ggtttgccgg gattaagcgg gttcattgcc gaaatgacta tcttcgtagg ttctttccag
     9181 aacaacgacg tattccaccg tacactgacc attatcgctt gttcatccat cgtgatcacg
     9241 gcagtctata tcctgcgtct ggtaggcaag attctgtacg gtacctgcac caacaaacat
     9301 catcttgcgc tgacagacgc aacctgggat gaacgggtag ctgttatctg cctcatcgtt
     9361 tgtgtagccg gactgggtat ggctcctttc tgggtaagcc acatgattgg tgaaagtgta
     9421 ctccctgtag tctcacaact catcccataa cctttatttt ttaatcttta attcttaatt
     9481 tataaagatg gattattcac aatttctaca tatgcgggaa gagctgtcgc tcgtagcagt
     9541 tttactattg ctgttccttg ccgatctctt catgagtccg gacgcacaca agcaaaaagg
     9601 gacgagaccc gttttgaaca ccatgctgcc agttatcctg atggccatcc atacagcgat
     9661 caatctggtt ccaggcacag ctgccgacat ttttggcggt atgtatcact atgtacccat
     9721 gcacacggtt gtcaaatcaa tcctgaacat aggcacgctg attgttttcc tgatggcaca
     9781 cgaatggatg aaacgcgacg atacttcatt caagcaaggt gagttctatg tacttacact
     9841 ctccaccctg ttcggtatgt atctcatgat ttccgccgga cacttcctga tgttcttcat
     9901 cggactggag acagcttcca tcccgatggc agccttgatc gctttcgaca aataccgcca
     9961 taactccgct gaagccggtg ccaagtatat ccttaccgca cttttctcca gcgcactgtt
    10021 actgtttggt ctgtcaatga tttacggttc cgcaggaaca ctgtatttcg atgatcttcc
    10081 tgctcatatc gatggaaatc cgttgcaaat catggctttt gtattcttct ttaccggtat
    10141 ggcgttcaag ctctctctgg ttccgttcca tttatggacg gcagacgttt acgaaggtgc
    10201 accgagtacg gttaccgcct atctgagtgt tatctccaaa ggttcggcag catttgtgct
    10261 gatggcaatt ctgatcaaag tattcgcacc gatgatacat gactggcaag aagtacttta
    10321 ctgggtgact atcgcttcta tcaccatcgc caatatattc gctatccgcc agcagaatct
    10381 gaaacgtctg atggcgttct ccagtatttc gcaggcagga tatatcatgc tgggtgtaat
    10441 cggaggaacg acacagggaa tgaccgccat ggtatattac atacttgtat atgccgctgc
    10501 caatctcgga gtatttgccg tcatcactat cgtagcatta cgcagtcaga agtttaccct
    10561 cgaagattat gcaggactct acaagacgaa cccgaaaatg gcttttctga tgactatttc
    10621 gctgttctca ctggcaggta ttcctccgtt tgccggattc ttctcgaagt tctttatttt
    10681 catggcagct ttcgaagcgg gcttccactt gctggtattc attgcactgg ttaataccgt
    10741 gatttcattg tactactatc tgctgattgt aaaagcaatg tatatcacgc cttccgataa
    10801 cccgattccg actttccgca gcgaccgctg tacaaagtgg ggactggcgc tctgcacact
    10861 gggcatcatc ggactgggta ttgcaagtat cgtatatcag tctatcgata aactatcatt
    10921 cggaatataa gaaaccgact ctttggggct gactttttag tcagccccat cattcttgtc
    10981 tattcttccg acatcaccac aaaacaggga aggctaaacc aaaaacgcga accctttccc
    11041 ggttcggatt ccacccctat ctttccgccc atttgttcca caatactttg gcagatggag
    11101 agtcccaggc ccgtgccgtg tacaaaggag ttcagcttca caaaacgttc aaaaatatgt
    11161 gcctgactct ctgcgtcaat accaactccc gtatcttgta catagaactc cagttcttct
    11221 cctttctgct tatatcccac acggatactt ccctccgagg taaacttaat cgcattgttc
    11281 acaaaattgg agattacctg gtgcagtcgg ttacggtcac taataatacg gcattccgca
    11341 agatgcggat cgaacatcag ttcgacattc tccttcacct tcatttgcat ggagcggaca
    11401 atatcttcac agagcatatt cacgtctaca tctccgttgg taaactcaaa tgtacccgct
    11461 tcaatcttag acaggtcgag tatatccgaa atcagttgta aaagcaggtc attgttctcc
    11521 ttcacaatct gaatatactc ccgccgttcc tctatatttt ccgtatcgac gagcaagtcg
    11581 gaaaagccaa cgatggcatt cagaggagta cgtatttcgt ggctcatgtt agcaaggaaa
    11641 gcacttttga gacggtccat catttcagct ttgtcacgtg ccaggatcaa ttctttctcc
    11701 gtctccttca gttcggtaat atcatagttg ataccgatga tttccacttc gttttcttcc
    11761 ggattgtatg tcgtaacgac tacattcata cgtatccagt tccattcatt cttcttgccg
    11821 ggacggcaga ttcgcatttc tccctgaaag tgcttccggt ttccttttct gacctcccga
    11881 tagaaatcaa aaatacgttc acggtcttcg ggatgcatat tacgatagac tcccaccacg
    11941 tccgccaatg gagtatcctc ttcttcacct aaatttttat accattgttt aatggcatat
    12001 cccttccggt tcagcagatt caacttggca tatcccacct ttgcataatc cgatatgagc
    12061 aggaagaaat tctcaaaatc acgaatacgg ttcatcgcat caatctgctc cgtattatca
    12121 atgctaatca ggatatagcc gttaaagttt ccttcgttat catagagctt gctgactttc
    12181 gtatatatat ctatcgtatc ccgacgatcg gggtgataat aaccttctgc ccgttcaaaa
    12241 gagtaattca gacggaagtc taccaaatct tcatcccgca cacggtcacg gatatgctgc
    12301 ggtacgttcg gattctcaaa gaagttgact cctatcacgt cctgtttat
//
