LOCUS       c00356_gnlPro..         8944 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LOJFJKPI_356.
ACCESSION   c00356_gnlPro..
VERSION     c00356_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 06:18:01
            Original ID  :: gnl|Prokka|LOJFJKPI_356
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8944
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1035
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg356_1"
                     /sec_met_domain="HBT (E-value: 1.2e-17, bitscore: 53.4,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNNFALFTYH
                     DDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEALVSLEGHW
                     KRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELNVKREEVIAIGDGVCDVTMIQ
                     LAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQLNAQARH
                     ALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGSMILCQPD
                     EIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSSIRVVNSV
                     MKKR"
     protocluster    1..8944
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4659]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..4659
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..8944
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8944
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             1032..2144
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg356_2"
                     /sec_met_domain="Chorismate_bind (E-value: 2.4e-58,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRVDKSCPIVLIQSDRTGQPLPMEIVAEEEQGLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             2164..3831
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg356_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-08, bitscore:
                     23.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKIIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIAIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             3835..4659
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg356_4"
                     /sec_met_domain="ECH_1 (E-value: 1.6e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             4663..5688
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg356_5"
                     /sec_met_domain="MR_MLE_C (E-value: 3.3e-30, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             5685..6791
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg356_6"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIEK
                     LLQSFIPVPFVITSVPDQRLGQAVTLLIEGQMEISALETKLESVLAPYYRPKYIYQVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(6765..7334)
                     /locus_tag="ctg356_7"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             7559..8482
                     /locus_tag="ctg356_8"
                     /transl_table=11
                     /translation="MENMNPESLLRKAQALGEDIKEMESIDVMGAYQQAQTQIKTNRRR
                     SMYNQLMRYAAFLTIPLLLSSLILGYLYWGATDTEEKYAEVMAATGSVIRYELPDHSVV
                     WLNSGSTLRYPTVFKKDNRNVELKGEAYFEVEADRKRPFYVNTPAGLSVYVYGTKFNVN
                     AYEDDNSIETVLEKGKVNVISPDGKTTVQLAPGERLLYNKVDQKLLKGKVDVYEKVAWK
                     DGKLIFRNAELGEIFKRLARHFNVDIQFNNISGKEYKYRATFRNETLPQILDYLAKSAA
                     LKWRTEEAVQQADDTFTKKKIIVDLY"
     CDS             8732..8944
                     /locus_tag="ctg356_9"
                     /transl_table=11
                     /translation="MRISLALLFAVVLQLSAENGYAQRTHVAISMNNVSVEQVLNKIEE
                     ASDYVFLYNDKTIQKNRIVSVRNKSG"
ORIGIN
        1 ctttcttata atggttgcca gataattaat gctcaaaacg gagaaatact gtttgagcgg
       61 aggattaatc cggaaatgtt gccttatctg gaaaagaagg caagaaaaaa taatttcgca
      121 ctgttcactt accatgatga tacgatcatt actgacactc cggagaatga acatatccag
      181 aatgaagctc gcttgaataa tttgaaagtg atcaaggaag aggaattttc tgtagcaatt
      241 gactttgctc cgtgtaagtg tatgcttgtc agcgatgacg aggaagcgtt ggttagtctg
      301 gaaggacact ggaagagacg gttgaacgga gctttggatg ttttccgttc cgaaccttat
      361 tttctggaag tagtgccgtg tgcgattgat aaagccaaca cattgggagc tttattggaa
      421 gaactgaatg tgaagcgtga agaagtcatc gctataggag acggtgtgtg cgatgtaacg
      481 atgattcagc tggcaggact gggagtggcg atggggcatt cgcaggattc ggtaaaggtc
      541 tgtgcggatt atgtgacagc ttccaatgag gaagacggag tggctctggc tgtcgaaaag
      601 gcgataatag cggaagttcg cgctgcagag attcctttgg accagttgaa tgcacaggcg
      661 cgtcacgcat tgatgggtaa tctgggtatc caatatacat atgccgacga agaccgtgta
      721 gaggcgacga tgccggtaga tcaccgtacc cgtcagccgt tcggtatttt gcacggtgga
      781 gctacgcttg cattgggaga aacagttgcc ggactcggct cgatgattct ctgtcagccg
      841 gatgaaattg tggtaggaat gcaggtcagc ggaaatcata tatcttctgc gcacgaaggt
      901 gatacagtac gtgcagtagc gacgattgta cacaaaggac gttcctccca tgtatggaat
      961 gtggacgttt ttacttcaac caataaactg gtgtcctcta tacgggtggt caacagtgtg
     1021 atgaaaaaaa gatgattgac gaaaaaagta acttgacaac tattgatgca cttattcagc
     1081 ggaaacagcc ctttgctgtt tatcgtgttc ccggggagaa gtatcctcgt ctgttgacag
     1141 aagatgtcgg agctgtccgc ctgattttcg atttgaaaga actgaatgga caaagaggat
     1201 ttgtgattgc tccgttccgt gtagataagt catgtccgat tgtgttgata cagtccgaca
     1261 ggactggaca accgttgcct atggaaatcg tggcagagga agagcagggc ttgcaaagtt
     1321 atccggagga atcttttcat accctttgta ctgggaagta tgcgacctgt tttcatacat
     1381 ttattgaagc cttgcgtgat gctacctttg ataaactggt gctttcccgt agtctcacta
     1441 ttggaaagaa tccggagttt tccccttcag ctgtttttcg tgcagcttgt caacgttata
     1501 ttcattccta tatctatctg tgttatactc ctcagacggg cgtgtggctg ggaagtactc
     1561 ccgaaattat attgtcgggc gaaaaaaatg aatggaacac agttgccctg gcaggaactc
     1621 aacctttgca gaatggtaaa cttccgcaag tatgggatga caaaaaccgt caggagcagg
     1681 attatgtggc gtcctatatc cgtcggcagc ttctttcgct gggcattcgc tccacagaga
     1741 gcggacctta tccggcttat gccggtgcct tgtcacatct gaaaactgat ttccatttct
     1801 ctttgaaaga taataaaaat ctgggagacc ttctgaaagt cctgcatccg actcctgccg
     1861 tgtgcggact gcctaaagaa gaagcctacc ggttcatttt ggaaaatgaa gggtacgatc
     1921 gtaagtatta ttccggtttt atcggttggc tcgatccgga gggacgcaca gatttgtatg
     1981 tgaatctgcg ttgcatgcac attgaagacg agcaattgac actgtatgcc ggtggcggat
     2041 tgttagcctc ttcagagttg aatgatgaat ggcaggaaac ggaaaagaaa ttgcagacga
     2101 tgaggcgtat tcttgtgtct gctccaataa tgatgaatca ttaacaagct aatcactatt
     2161 aatatgtatt cggacaagaa aaatatactc cagttggtcg cgctgcttga ggcgcatgga
     2221 attacgaaag tagtgttatg tcccggtagc cgtaatgcac ctattgtgca tacgctgtct
     2281 actcatccgg gttttacttg ttatgctatg acggatgaac ggagtgccgg ttattttgcg
     2341 attggtcttg cgctgaatgg cgggcatcct gctgccgttt gctgtacttc cggtacagcg
     2401 ttgctcaatc ttcatcctgc tgtggcagaa gcgtattatc agaatatacc tttagttgtt
     2461 atctctgccg atcggcctgc tgcctggatt ggacagatgg cgggacagac attgccgcag
     2521 cccggtgttt ttcagacatt ggtcaagaag tcggtaaacc ttccggagat tcagacagaa
     2581 gaggatgaat ggtactgtaa ccgcttggtg aatgaagcct tgctggaaac caaccatcat
     2641 ggaaaaggtc cggtacatat taatattcct atatccgaac ctttgttcca gtttacggtg
     2701 gagtcgcttc ccgaagtacg tgtcatcacg cgctatcagg ggctgaatgt atacgaccgg
     2761 gattacaatg acctgatcga acgcttgaac agatatcaga agcggatgat tattgtcgga
     2821 cagatgaact tgatttactt gtttgagaaa cggcatacca aattgttata taaacatttc
     2881 gtgtggctga ccgagcatat cggtaatcag acagtacccg gtattccagt gaagaatttt
     2941 gatgcggcgc tttatgcgat gcccgaagag aaaaccggcc agatgactcc cgagttattg
     3001 attacttatg gcggacatgt ggtttccaag cggttgaaaa aatatcttcg gcagcatccg
     3061 cctaaagaac actggcatgt gtctgctgat ggagaagtgg ttgaccttta cggttctctg
     3121 actaccgtca tcgaaatgga cccgtttgag tttctggaga aaatagctcc attgctggat
     3181 aaccgcgtgc cggagtatcc ccgtgtatgg gagaattatt gcaagatcat tcccgaaccg
     3241 gagttcggat attcggaaat gtcggctatc ggtgctttga taaaagcatt gccggaatca
     3301 tgtgcattgc atctggcaaa tagttctgtt atccgctatg ctcagttata ccaggttcct
     3361 tctacgattg aggtatgctg taatcggggt acaagcggca tcgaaggctc gttgtccacg
     3421 gcagtgggat atgctgccgg ttcggataaa ctaaatttta tagctatagg tgaccttagt
     3481 ttcttttatg atatgaatgc tttgtggaat atcaatgtcc gtcctaatct acgcattctt
     3541 ttgctgaata acggaggagg ggagattttc catacattac ccggactgga tatgtcgggt
     3601 acatcgcaca agtatattac agccgttcac aagacatctg ccaaaggatg ggcggaagaa
     3661 cgcggattcc tttatcaacg ggtagagaat gaagaacagc ttgccgaagc gatgaaaacc
     3721 ttcacacaac cggaagccat ggaacaaccg gttctgatgg aagtattcag caataaaaat
     3781 aaagatgcac gtatactgaa agattattat catcaactaa aacaaaaata gattatgtca
     3841 acacaaagag aatggacaac catcagagaa tacgaagata tcctctttga ttactataat
     3901 gggattgccc gcatcaccat taaccgtgaa cgctatcgaa atgcatttac tccgactaca
     3961 acggctgaaa tgagtgacgc attgcgcatt tgccgggaag aagcggatat tgatgtgatc
     4021 gtgattacgg gagctggtga caaggctttc tgttcgggcg gtgaccagaa tgtgaaaggg
     4081 cgtggcggct atatcggcaa ggacggtgtt ccccgtctga gtgttctgga tgtacagaaa
     4141 caaatccgca gcattccgaa accggtaatt gctgccgtaa atggatttgc cattggtggc
     4201 ggacacgtgc ttcatgtagt ttgcgattta tcgattgctt cggagaatgc gatcttcgga
     4261 cagaccggtc ctcgcgtagg tagctttgat gcaggtttcg gagcctctta tctggctcgt
     4321 gtcgtcggtc agaagaaggc acgtgagata tggttccttt gccggaaata caatgcgcag
     4381 gaagcgttgg atatgggatt ggtgaataaa gtagttccat tggagcaact ggaggatgag
     4441 tatgtgcaat gggcggaaga aatgatgctg ctcagtccgt tggccttgcg gatgattaaa
     4501 gccggattga atgccgaact ggacggccag gcaggtattc aggagctggc aggggatgcg
     4561 accttgcttt actatctgac ggatgaggct caggaaggaa agaatgcatt tctggagaaa
     4621 cgtaaaccta actttaagaa atatccgaag ttcccttaaa caatggattg caaaatagac
     4681 attattccgc gggtgcttca tttcaagcag ccggccggaa cttcacgagg cacatacaca
     4741 acgcgaaaag tctggtatct tcattttact gctcccgaat ttcccaattg ggtagggatc
     4801 ggggagtgcg ctcctctgcc aaatcttagc tgtgatgatc ttcccgatta cgaggaagtg
     4861 ctggctaaaa tctgccggca ggtagagaat cagggaggta agctggacat ggaagctcta
     4921 tgcaagtacc cttccatcct ttttggcttg gagacagcca ttcgtcactt ttttgaagga
     4981 agctgggctt tgtgggatac acccttctca cgtggggaag caggtattcc gataaacggg
     5041 cttatctgga tgggtgactt caatagaatg cttgctcaga tagagaagaa gatggaggcg
     5101 ggattccgct gtataaagtt gaagatcggt gccatcaact ttgaagaaga actggcttta
     5161 ctccaacata tccgctctca ctattcttct aaagaaatag aattgcgtgt agatgccaac
     5221 ggagcattct caccaacaga tgcgatggag aaattgaaac gcttgtccga actggactta
     5281 cattcgatag aacagcccat tcgtgccgga caatgggaag aaatggcacg tcttacttcc
     5341 gaatctcctt tgccgatagc tttggatgag gaactgatag gctataatac ctgggaagaa
     5401 aagcaaagat tactttcggc tatccgtccg caatatatta ttatcaaacc ttctcttcat
     5461 ggcggattag ccggtggcga ggagtggatt gcagaagcgg agaaactgaa tatcggttgg
     5521 tggataactt ctgctctgga gtctaatatc ggtctgaatg ctatcgctca atggtgtgct
     5581 acttttcaga atccattgcc gcaagggtta ggcaccgggt tactctttac agataatgta
     5641 gagatgcctc ttgaaatcag aaaagattgt ttgtggtttt gtaaatgatg atattcgacc
     5701 gacaaaaaca gcgtttgttg ctggagggaa aggaatatac tccgggcgat atacatagcc
     5761 ttgtagcaga aggtgaggga aaccaccctt ctgctatatg ggacttgtat ctttttctaa
     5821 acgaatggtt taatgatgat cctgtgatca ctgtacatac ttccggttct acgggggcac
     5881 ctaaagaatt gcttgttcgc aaagatcaga tgatacagag tgcacgcctg acttgtgagt
     5941 ttctggattt aaagcagggt gaaacggcat tattgtgtat gaaccttcgc tatatcgggg
     6001 cgatgatggt agtcgtccgt tctttgattg ccgggttgaa tcttatagta cgtcgggctt
     6061 ccggtcatcc attggcagat gtggacactc ctttaaggtt tgcggctatg gtgcctttgc
     6121 aggtgtataa tacatttcag atacccgaag agaaagagaa attaaagcaa acggagattt
     6181 taattatagg aggcggagca gttgacaagg ctttagagga aaaaatcaga aatctgtcca
     6241 atgctgttta ttcaacttac gggatgacgg aaaccctttc tcacatcgct cttcgccgtc
     6301 tgaatggtgc agcagcatcc gatcgttatt atcctttttc atccgtagag ttgtttttgt
     6361 cttcagaaaa tactttgatg attaatgctc cgcttgtctg cgatgatact ctgcagacaa
     6421 atgatattgc ccgcatttat ccggacggta gttttacgat tctgggaaga aaggataatg
     6481 taatcaatag cggaggaatt aaagtgcagg cagaagagat cgaaaagtta cttcagtcgt
     6541 ttattcctgt cccgtttgta atcacttccg ttccggatca acgtttgggg caggctgtta
     6601 ctttattgat agaagggcag atggaaataa gtgcgctaga gactaaattg gaatcagtct
     6661 tagcacctta ttatcgtcct aaatatattt atcaggtaaa tcatattcct caaacgggaa
     6721 atgggaagat taatcgtaaa gagtgccgtg ttttagcaga gagcttacag ttgctcggga
     6781 gacaggaata ataaaaatag cgggaggtaa tctttcaact cgttccgcag gagttccatt
     6841 gttttttgtt tataccgatt aatggatttt acgctgagat tcatttcttc ggcaatttcc
     6901 gcatgtgttt tgccttcaaa gaaactcttc ataaatacgg tgcgatagtt ttccggaagc
     6961 ttatttaatg tttcgtatag cattcggtat aactcatcaa gtgtatatac actatctgtt
     7021 tctgtttcat atagaggagc tttcttttgg atattttcgg cataactcca ttcatactcc
     7081 tgatgtttca gaaagttcaa acagctgttt tttacacaca tttttatata tcccaatgct
     7141 gtctctgatt gcaaatcgaa agagtcggta tccaacttgt cccataggga ggtgaataca
     7201 tccgaaacaa tgtcctcgcg gacttcttta tcatctacaa atctttttgc atacaggcag
     7261 aaaggggcat aataatcctc gtaaagttgt ttgaaagctc tttctttagt ctgtctggaa
     7321 aaagatattt tcattatttt gagattctgt agtttttcat tttactgcaa atatataata
     7381 agaaaatcag catttcctaa aattttcttt ctttttttgt ttttggtatg aagctgtgga
     7441 aaataagata gcttaaaaaa taaaataaaa aaaagtatgt tatacctgtc ccttttcgat
     7501 tacctcagtt gtactattag tgtaattgca attaaaagat aagattttga aagagaatat
     7561 ggaaaatatg aatccggaat cattgctccg aaaagcgcag gcattaggag aggatattaa
     7621 ggaaatggag tctattgatg taatgggtgc ctatcaacaa gcacagaccc aaataaagac
     7681 aaacagaaga aggagtatgt ataatcagtt gatgcgttat gctgcattct tgactatacc
     7741 tttattactt tcttctttga ttttgggata tttatattgg ggagcaacgg atactgaaga
     7801 gaagtatgca gaagtcatgg cggctacagg ttcagtcatt cgttacgaac ttcctgacca
     7861 ttcggttgtc tggttaaact ccggtagtac tttacgttat cctaccgttt ttaagaaaga
     7921 taatcgtaat gttgaattaa aaggtgaagc ctattttgaa gtagaagcgg acaggaaacg
     7981 gcctttttac gtcaatactc ctgccgggtt aagtgtctat gtgtacggaa ccaaatttaa
     8041 tgtgaatgct tacgaagatg ataatagtat agaaacggta ttagaaaagg gtaaagtaaa
     8101 cgttatttca ccggacggaa aaacaacagt tcagttagct ccaggagaac gattgcttta
     8161 taataaggta gatcagaaat tgttgaaggg aaaagtggat gtttatgaaa aggtggcatg
     8221 gaaagacggt aagttgatat tccgcaatgc cgagttgggt gaaatattca aacggctggc
     8281 acggcatttt aatgtagata ttcagtttaa taatatatcg ggaaaagaat ataaatatcg
     8341 tgcgaccttc cgtaatgaaa cactgccaca gatattggat tatctggcta agtctgctgc
     8401 cttgaagtgg agaactgagg aggcggtaca acaggcagat gatacattca caaagaaaaa
     8461 gataatagta gatttatatt agtaaccata aaaatgagaa tagcctatga gataacacaa
     8521 agatcgtaaa aaaaggaaga aagctgctac caacagctgt cttcccccaa tttttcagat
     8581 tcgcggtaag gagtcttgca aacgctaacc ggaatcaaac cacagttcat tatagtaata
     8641 aactttagtt aaccgcaaat gtatgaaaaa aaatcattca tttattgcat tatatcctaa
     8701 atatgcttta aatctaaaac tacctttagt tatgaggatt agtctggcac tactttttgc
     8761 agtcgtttta caactatctg cagagaatgg ctatgctcaa cggacgcatg ttgccatttc
     8821 tatgaacaat gtatctgtag aacaggtact gaataaaata gaagaagctt ccgattatgt
     8881 tttcctttac aatgacaaaa cgattcagaa gaatcgtatt gtttctgtga gaaataaatc
     8941 aggt
//
