LOCUS       c00163_gnlPro..        15592 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKPOCELB_163.
ACCESSION   c00163_gnlPro..
VERSION     c00163_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:36:34
            Original ID  :: gnl|Prokka|PKPOCELB_163
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15592
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..228)
                     /locus_tag="ctg163_1"
                     /transl_table=11
                     /translation="MFFANVPVPIASLPVLYAYTVNPLVFNTSKFTDVALVVLLTTLLN
                     PISAVFAAFSISSFCEQPVIANAATAANKIF"
     protocluster    1..15592
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2172:5592]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2173..5592
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15592
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15592
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             398..1009
                     /locus_tag="ctg163_2"
                     /transl_table=11
                     /translation="VPADATKQEDLLVAKANDLTKTDAKVNFIFSHALTQVNFSIKSKV
                     NDGLTYEVTDISISEVGNKATYNYGTGWSEPTATTSSYTYPISKTATDNQVAGDASTVK
                     ILDTSNLMMLLPQTLSNKAKILVKYKVMDKNGDTVYGDALTTGKEIVIGDGTTKWGMGK
                     KVRYTLALTNNATSIGWEVTSVDEWTKDNEEDKGVETPAK"
     CDS             1277..1990
                     /locus_tag="ctg163_3"
                     /transl_table=11
                     /translation="LFLIKGEMLVNSREYAGTMLKAGEFMLQPISSKIEMLAMTDVECI
                     YYQFNQPELFCDIRYNRIMKETDPPLIPSPLPIIPELQHFLESARTYLSEKKICRDLLS
                     LKRKELAFILGYFYSDYDLASLVHPLSKYTSSFECFVYQNYKKVKTVEEFAKLGGYSQT
                     TFRRIFDHVFHEPVYEWMLSRRKEEIIYELQNTEATISEICYKFGFESLPHFSNFCKKS
                     FGTSPRSIRLKRSSE"
     CDS             complement(2173..2457)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_4"
                     /sec_met_domain="Fer4_7 (E-value: 2e-13, bitscore: 41.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-07, bitscore: 22.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-07, bitscore: 22.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAAACIGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKVEAARR
                     AKAMLSKMDELGFGNCTNTRACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             2749..2913
                     /locus_tag="ctg163_5"
                     /transl_table=11
                     /translation="MVEYDRFATVINNLFVQDIQHFEERRIARDIFHLICFKSTFCFRA
                     FLAPYLQCE"
     CDS             complement(2958..4052)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.4e-17, bitscore:
                     52.3, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-38,
                     bitscore: 122.6, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESLRNDGRIWVPKKIEDAKALQAGTKKPTEIPDEDRDFYLERR
                     YPAFGNLVPRDVASRAAKERCDAGFGVNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFD
                     MYEEITDENPYKTPMMIFPAIHYTMGGIWVDYELMTSIPGLFAIGEANFSDHGANRLGA
                     SALMQGLADGYFVLPYTIQNYLADQIQVPRFSTDLPEFAAAEKEVKDKIQKIKAVNGKH
                     SVDSIHKKLGHIMWDFVGMARTKESLQKALTGIEEVKKDFWTNVRIPGDVNELNVELEK
                     ALRLIDFIEVGMLMARDGLNREESCGGHFRTEYQTPEGEALRDDKNFSYVACWKYTGEN
                     SEPELIKEDLNYQFVKVQTRNYKS"
     CDS             complement(4514..4771)
                     /locus_tag="ctg163_7"
                     /transl_table=11
                     /translation="LPEHLLPLLWAKWVSEYSISVFRIHPAVLTLLQHRVVSTQLKTIK
                     MMVTRFTVFSTIQSKAVTTVHAKPTFTVWLRYQTLSSTNA"
     CDS             complement(4939..5592)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg163_8"
                     /sec_met_domain="SucD_FumR (E-value: 3.7e-121, bitscore:
                     392.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVTGIALVLFLTFHMAMNLVAIISAEGYNLVCEFLGANWYALVA
                     TLGLAALFVIHIIYAFWLTIQNRAARGSERYAVVDKPKTVEWASQNMLVLGIIVILGLG
                     LHLFNFWAKMQLPELVHNMGGVADTTYAADGVYHIMNTFSNPVYVVLYLVWLGALWFHL
                     THGFWSSMQSLGWNNKIWINRWKCISNIYSTIVVVCFALVVVVFFVKSLACGAC"
     CDS             complement(6314..6823)
                     /locus_tag="ctg163_9"
                     /transl_table=11
                     /translation="MTQRITNFMKDICDYLDEQMPCGAFIDLKCQELMYLIICYYPIPQ
                     LSKFFYPISSYTESFQYFVMQNYEKVKNVEEFAHLGGYTTTTFRRLFKNMYGVPVYEWI
                     LSKKREGILEDLQHTKQRITEISNRYGFDSLSHFAHFCKASFGDSPRALRTRAARGEKI
                     TALKTE"
     CDS             complement(7383..7649)
                     /locus_tag="ctg163_10"
                     /transl_table=11
                     /translation="MTTCIYPIRITVVGTLTVKSIFHTIRNHDCLGHTRTDVNGIFQQL
                     FIFIDTCIYSHRHRYTYRNIRCRFRKGFAIIPRKLTIKTVYFM"
     CDS             complement(8012..9265)
                     /locus_tag="ctg163_11"
                     /transl_table=11
                     /translation="VNDTAIAGVKMGTEEIMGRLRGPKDSKVNLTIIRRGVKEPLLFNV
                     KRDKIPILSLDAAYMIQPKIGYIRINRFGATTAEEFLKALKELQKKGMKDLILDLQGNG
                     GGYLNAAIDLANEFLGQKELIVYTEGRSAQRSEFFAKGNGNFRNGRLVVLVDEYSASAS
                     EIVTGAIQDWDRGVVVGRRSFGKGLVQRPIDLPDGSMIRLTIARYYTPAGRCIQKPYDS
                     SINEKSGKGKSSESSIEKYNQDLIDRYNHGEMVSADSIHFPDSLKCQTKKLGRTVYGGG
                     GIMPDYFVPVDTTLYTDYHRNLVAKGVVIKTTMNFIEKNRKALLDKYKTFEKFNEKFEI
                     DDQLLNYLREAADKEKIEFNEEQYNKALPLIKAQLKALIARDLWDMNEYFQVMNATNKS
                     VERALEILNDKEYEKILK"
     CDS             9326..9517
                     /locus_tag="ctg163_12"
                     /transl_table=11
                     /translation="LYDEQRIFDHLKLYTYPFEIALERFIHFLHLFGIRIGGMRVELCQ
                     HFYDGRFNQFVFIDRIYI"
     CDS             9468..9698
                     /locus_tag="ctg163_13"
                     /transl_table=11
                     /translation="MMADSTSLFSLTVSTYKLEMANSASCNFRMAGEPKFCACSPKTEH
                     KPISRYIILFMITWVYYISIPLGMNILISLL"
     CDS             complement(9650..10102)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg163_14"
                     /sec_met_domain="CTP_transf_like (E-value: 1.8e-21,
                     bitscore: 67.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHYSVVQRTLTFMDEVVIGIGINENKNTYF
                     PIEKRVEMIRKFYKDEPRIKVESYDCLTIDFARQVDAQFIVRGIRTVKDFEYEETIADI
                     NRKLAGIETILLFTEPELTCVSSTIVRELLGYNKDISMFIPKGMEM"
     CDS             complement(10105..11976)
                     /locus_tag="ctg163_15"
                     /transl_table=11
                     /translation="MEENELIPVDNNPVEYTDDNIRHLSDMEHVRTRPGMYIGKLGDGS
                     HPEDGIYVLLKEVIDNSIDEFKMQSGKKIEIRVEENLRVSVRDYGRGIPQGKLIEAVSV
                     LNTGGKYDSKAFKKSVGLNGVGVKAVNALSSNFEVRSYRDGKVRCATFTKGELVTDHTE
                     DTEEENGTYIFFEPDETLFLNYSFRPEFIETMLRNYTYLNTGLAIIYNGQRILSRNGLV
                     DLLNDNMTATGLYPIVHLKGEDIEIAFTHTGQYGEEYYSFVNGQHTTQGGTHQSAFKEH
                     IARTIKEFYNKNQDYTDIRNGLVAAIAVNVEEPMFESQTKIKLGSTNMSPGGITVNKFV
                     GDFIKQEVDNFLHKHADVAEIMLQKIQDSEKERKAIAGVTKLARERAKKANLHNRKLRD
                     CRVHLNDVKGKGLEEESCIFITEGDSASGSITKSRDVNTQAVFSLRGKPLNSFGLTKKV
                     VYENEEFNLLQAALNIEDGIEGLRYNKVIVATDADVDGMHIRLLLITFFLQFFPDLIKK
                     GHVYILQTPLFRVRNKKKTLYCYTEEERVNAIKELSPNPEITRFKGLGEISPDEFRHFI
                     GKDMRLEQVSLRKTDTVKELLEFYMGKNTMERQNFIIDNLVIEEDIA"
     CDS             complement(11982..13118)
                     /locus_tag="ctg163_16"
                     /transl_table=11
                     /translation="MAITIKKVSTKRELKKFIRFNYELYKENPYSVPDLYDDMLNTFNK
                     KKNAAFEFCEAEYFLAYKDGKIVGRIAGIINHRANATWNKKDVRFGWIDFIDDLEVSSR
                     LLQTVEEWGKSKGMENIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNHPYYPQHMEKLG
                     FEKDADWVEYKIYIPDAIPEKHQRISDLIQRKYNLKIKKYTSSRKIAADYGQAIFELMN
                     EAYSPLYGYSPLSQRQIDQYVKMYLPIVDLRMVTLITDAEDKLIAVGISMPSLSEALQK
                     SHGRLLPLGWYYLLKALFMKRRAKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQKLGF
                     IFAESNPELEMNGKVQAQWEYFKTEQHKRRRAFTKKID"
     CDS             complement(13207..14124)
                     /locus_tag="ctg163_17"
                     /transl_table=11
                     /translation="LIGANCLTDGAASVAKRFRIPSIVIGLTIVAFGTSAPELTVSVSS
                     ALKGSADIAVGNVVGSNIFNTLMIVGCTALFAPIVITRNTLRKEIPLCILSSIVLLICA
                     NDVFLNKASSNILSISDGLILLCFFTIFLGYTFAIASPTNNTQPEEEIKSLPMWKSVLF
                     ILGGLAGLIFGGQWFVEGASNIARHLGVSESVIGLTLVAGGTSLPELATSIVAALKKNP
                     EIAIGNVIGSNLFNIFFVLGCSASITPLRLTGINNFDLFTLVGSGILLWFFGLFFAKRT
                     ITRIEGSILVLCYIAYTTYLIYQI"
ORIGIN
        1 aaagatttta tttgcggcag ttgctgcatt ggcaatcaca ggttgctcac agaatgagga
       61 gattgagaag gcggcgaaaa ctgcggagat tgggttcaat agcgtagtca gtaaaacgac
      121 aagagctaca tcagtaaatt tagatgtatt gaaaaccaat ggatttacgg tatatgcata
      181 taatactggt aatgatgcaa tgggtactgg tacattggcg aaaaacatta tagataaaga
      241 gcctattaca tggaatggta cagacagctg gcttgggagt aaagcctatt attggcctaa
      301 cagtggtaaa atacaatttt ttgcatattc ttcaaagaat gttacagggt taactgctca
      361 atctagtgat gtttatccta caatagtcga ttatgaagtg cctgctgatg ctacaaagca
      421 agaagatctg ttggttgcaa aagctaatga tttaactaaa actgatgcca aagtaaactt
      481 tatattctca catgctctta ctcaggttaa cttttcaata aagtctaagg ttaatgatgg
      541 gttgacttat gaggtaacag atatttctat tagcgaggtc ggtaataaag caacttataa
      601 ttatggtact ggctggagtg agccaactgc tactacttct tcttatactt atccaataag
      661 taaaactgct actgataacc aagtggctgg agatgcgagt actgtgaaaa tcttagatac
      721 ttctaatttg atgatgttgt tgccacagac tttgtctaat aaagcaaaga tacttgtgaa
      781 gtataaagta atggataaga atggtgatac tgtttacggt gatgctctta ctactggcaa
      841 ggaaattgtg attggcgatg gaactactaa atggggaatg ggtaagaaag tacgttatac
      901 attggcgttg actaacaatg ctacttccat aggttgggaa gtgacaagtg ttgatgaatg
      961 gacaaaagat aatgaggagg ataagggtgt cgagactcct gctaagtgaa ttttgtaaaa
     1021 ctatagagca ttaaaatgat attccttgga aacttaagtt aattaagttt tcagggaata
     1081 ttttttatat ttaaataatt ctcttacatt tgtcgcaaac atacaaacaa acacacccgt
     1141 atatatgccc agctccgttt gtggagatcc catgatgtgt cagaactgca aaaagtcagt
     1201 tcctaatgcc attttccatg tttaccatag acgtggtttc cattatcctg cacaaaaatg
     1261 tgaggagaat ttcattttgt tccttatcaa gggagaaatg ctggtgaata gccgggagta
     1321 tgccggaacg atgcttaagg ccggagaatt tatgcttcag cccatcagtt cgaaaataga
     1381 aatgctggcc atgaccgatg tggaatgtat ctattatcag tttaatcaac ctgaattgtt
     1441 ttgtgatatc cggtataatc gtatcatgaa ggagactgat cctccgttaa ttccctcacc
     1501 cttacccatt attcccgaac ttcaacattt tcttgagtct gcacgtactt atctgagcga
     1561 aaagaagatt tgtcgggatc tcttatcatt aaagcggaaa gagcttgctt tcatactcgg
     1621 ttatttttat tcggattatg acctggcttc cctggtacat cctctctcaa aatatacctc
     1681 ttcgtttgag tgctttgtat atcagaacta taagaaggtg aagactgttg aagagtttgc
     1741 taaacttgga ggatatagtc agactacatt caggaggatt ttcgatcatg tttttcatga
     1801 gccggtgtat gagtggatgc ttagtcgccg caaagaggag atcatttacg aacttcagaa
     1861 tacagaggct accatctctg aaatctgtta taaattcggg ttcgaatctt taccgcattt
     1921 ctcaaacttc tgtaaaaagt catttggtac ctcgccacgc agcattcgat tgaagcgttc
     1981 atccgaatga gatgataaac ttggatcttt tttcgacaaa cttagttgga ttttgattct
     2041 tttaaatgct gtattcggca ctaccgcaga tttttttgcc acgataagat tcttatcgaa
     2101 ataaacaaaa gaggctgtcc caaaaagtgg gacagcctct ttcctactta ttaatcaaat
     2161 gctaagttgt gcttagtctt tcagttttgc gatgatgaaa tcgcggttca aacgagcgat
     2221 gttgctgatt gaaatgttct tcggacactc tgcttcacaa gcacgtgtgt ttgtacagtt
     2281 accgaatccc agttcgtcca tcttagaaag catagctttt gcacggcgtg ctgcttctac
     2341 ttttccttgt ggaaggaggt tcagctggct gaccttagct gatacgaaca acatggcaga
     2401 accattctta caagcagcta cacaagcacc gcaaccgata catgcagcgg catccatagc
     2461 ctcgtcggcg atatccttag agataaggat agcgttggca tcctgaggag cacctgtgtt
     2521 tacgcttacg taaccaccgg cctgcatgat cttgtcataa gccgaacggt caaccatcaa
     2581 gtcacggatt accgggaaac cggcagaacg ccaaggttca actgtgatgg tgtctccatc
     2641 tttgaagcga cgcatataca tctggcaggt agtagcacct gtcgcaggtc cgtgcgggtg
     2701 tccgttgatg taaagagaac acatgccgca gataccttcg cggcagtcat ggtcgaatac
     2761 gataggttcg ccaccgtcat taataatctg ttcgttcagg atatccagca tttcgaggaa
     2821 cgacgtatcg cccgggatat ctttcatttg atatgtttca aaagcacctt ttgctttcgg
     2881 gcctttctgg cgccatacct tcagtgtgaa tgatatattt ttatccattt ttgttttcct
     2941 ttaattgatt agccgaatta tgacttgtag ttacgagtct gaacttttac gaactggtag
     3001 ttcaaatctt ctttgatcaa ctccggttct gaattttcac cggtgtattt ccagcaagct
     3061 acgtatgaga agttcttatc gtcacgtaac gcttcacctt ccggggtctg gtattcggta
     3121 cggaagtgtc caccgcaaga ttcttcacgg ttcaaaccgt cgcgagccat caacatacct
     3181 acttcaatga agtcaatcag acgaagtgct ttttccagtt ctacgttcag ttcgtttaca
     3241 tcacccggga tgcgaacgtt ggtccagaaa tctttcttca cctcttcaat gcctgtcagg
     3301 gctttctgca gagattcttt tgtacgggcc atacctacga agtcccacat gatgtgaccc
     3361 agtttcttgt ggatagagtc aacagagtgt tttccgttta cggctttgat cttctggatc
     3421 ttatctttca cttccttttc ggctgcagca aattccggca ggtcggtaga gaagcgcgga
     3481 acctgaatct gatcggccag gtagttctgg atagtgtaag gcaatacgaa gtatccgtca
     3541 gccagaccct gcatcaatgc agatgcaccc aagcggttag caccgtggtc ggagaagttg
     3601 gcttcaccga tagcgaacag acccgggata gaagtcatca attcataatc aacccagata
     3661 ccacccatgg tgtagtggat agcggggaat atcatcatcg gagtcttgta cgggttctcg
     3721 tcagtgattt cttcgtacat gtcgaagagg ttaccataac gggcacgaac cacgtcctca
     3781 cccagacgat cgatagcata tttgaaatcg aggaagacgg ccaaaccggt attgttcaca
     3841 ccgaaaccgg catcacaacg ttctttggct gcacgtgaag caacgtcacg cggaacaagg
     3901 ttaccgaatg ccgggtaacg gcgttccaga tagaagtcac ggtcttcatc aggaatttcg
     3961 gtcggctttt tagtgcctgc ctgcaatgct ttggcatctt caatcttctt cggaacccag
     4021 atgcgaccgt cgttacgaag tgattcagac atcaatgtca gcttagactg cttgtcaccg
     4081 tgtacgggga tacaagtcgg gtgaatctga gcgaaacaag gattggcaaa ataagcacct
     4141 ttcttatagc actggatggc aactgaaccg ttggaaccca tagcgttggt agaaaggaag
     4201 aatgcgtttc cgtaaccacc tgtaccgata actacagcgt gagcagcgaa acgttcgatt
     4261 tcaccggtta cgaggttacg ggcaatgata ccgcgcgcac gtccttcaat tacaacgagg
     4321 tcgagcattt cgtaacgagt gtaaagttta acagtacctt tttgtacctg acggctcaat
     4381 gctgaataag cgcccagcaa cagctgctgt ccggtctggc cgcgggcata gaacgtacgg
     4441 gatacctgtg caccaccgaa tgaacggttg tcaagtgtgc caccgtaatc gcgtgcgaaa
     4501 ggtacaccct gtgctacgca ttggtcgatg atagcgtttg atacctcagc cagacggtaa
     4561 acgttggctt cgcgtgcacg gtagtcaccg cctttgattg tatcgtagaa aagacggtaa
     4621 accgagtcac catcattttg atagttttta gctgcgttga taccaccctg tgctgcaata
     4681 gagtgagcac ggcggggtga atcctgaata cagaaattga atactctgaa acccatttcg
     4741 cccaaagaag cggcagcaga tgctccggca agtccggtac ctacaacgat aatgtcaagg
     4801 cgacgtttgt tggcagggtt aacaagtttt tgatgagcct tatagttact ccatttttcg
     4861 gcgagctggc cttcaggaat ttttgaatct atcttagtca taatgctatt tacaatttaa
     4921 tcatttacaa tttacaattt agcaagcacc gcatgccaac gatttaacga agaatacgac
     4981 tactaccaga gcaaagcata caacaacgat ggttgaatag atgttggaga tgcatttcca
     5041 gcggttgatc caaatcttgt tgttccagcc caaagattgc atagagctcc agaaaccatg
     5101 agtcaggtgg aaccaaaggg cgcccagcca aacgaggtac agcactacat atacagggtt
     5161 agagaaagtg ttcatgatgt gataaacacc atcagcagca taagttgtgt ctgctactcc
     5221 tcccatgttg tgcaccaatt caggtaactg cattttagcc cagaagttaa agaggtgaag
     5281 gcccaaacct aagataacga tgatacccag caccagcatg ttttgtgatg cccattccac
     5341 ggttttaggt ttgtcaacta cggcgtaacg ttcgctacca cgtgctgcgc gattctgtat
     5401 tgtcagccag aaagcgtaga taatgtgaat cacgaagagg gcagccaggc ccagcgtagc
     5461 taccaacgca taccagtttg ctcccaggaa ctcacaaacc aagttgtaac cctcagccga
     5521 gatgatcgca acaaggttca tcgccatgtg aaacgttaga aacaggacaa gggcgatacc
     5581 ggtaacgctc atcaccactt tccttcctac agatgaatta cttaaccaca taaatgattg
     5641 attttaaatt atttaattgt tagaactata atttctgttt tacgagcctt ctttctcatt
     5701 gtgcaaaagt acacgaaata cattgattaa ccaaagaatt aaagaaataa ttctttaatc
     5761 ctgaatgtcc ggagaggatg gggtaaacgg gacgatcggt tggggttata aaggatttgt
     5821 cgtgaatctg ttagaatagt aaaatctttg tctttaagaa gttagctttt ggagtcgtta
     5881 tcatgcttat atttaattgg tcgttttccg aggtttcctc taattctctt ttctgtgcat
     5941 gaattaagaa gaaaacaagt caaatggaca tcatttataa tactttgtaa ataagagtat
     6001 tactgtacct tctgatatgt ttatgtgagc cttgctatct gggctcatgg gcacagatat
     6061 acaggacgag ataaagaaaa gactattttc actaaagata gcaagaaaaa taaaatactc
     6121 taaatgatat agatagaaat atagttatat acatttggat atcagcatga tgtattgtat
     6181 tccagctctt gtccggaggg tggaagatgg aagattgaaa tccatttacg tgggagaagt
     6241 atccgactga tccgaagaat gagaagggga ttcggatgaa gctttgcccg ttatcgggta
     6301 aagagagcgg tttctattct gtttttaaag cagtaatttt ttcacctctg gctgcacgtg
     6361 tacgaagggc acgtggagag tctccaaagg aagctttgca gaaatgtgca aaatgtgata
     6421 aagagtcgaa tccgtaacga ttactgatct cggtgatccg ttgtttggta tgctggaggt
     6481 cttccaggat gccttctctt ttcttgctca gaatccattc gtatacaggt acgccataca
     6541 tgttcttgaa taaacggcga aaagtggtag tggtatagcc tcccaggtgt gcaaactcct
     6601 ctacgttttt caccttttcg taattctgca tgacgaaata ttggaaactt tccgtatagc
     6661 tgctgatggg atagaaaaac ttgctcaact ggggtatcgg gtaataacag atgatcagat
     6721 acatcagttc ctgacatttc agatcgatga atgcgccgca aggcatctgt tcatcgaggt
     6781 aatcacaaat atctttcatg aagttggtta tgcgttgtgt cataaccaat ggtgtataag
     6841 ttagcggagc ttctgattgt tgcaggatct catgatagcg ctgttcacag atcaggggtg
     6901 gttcgttgaa ccagtacact acataattta cgtctgtcag tgccagtaat tctaatttgg
     6961 agccgatgga ctggagaata aattgtcctt cacgtaatgt ggtgccggga tactcttcac
     7021 tgttgaccag taattctcct tgtagtataa acaggataca attttgtgtg catttgtcgg
     7081 gcggaaaatg ttgtcctttg ggaaacttcc ggtgaacaag tatgccttct gtagctttgg
     7141 gacattgcgc acaatctgtc tgtctattac attgagtttc tctggccatg aattaaagtt
     7201 aggtgtcagg gtaaataata cttagggaac aaagataggt tttttttgcg aaaactctgt
     7261 ctttttaatc tatctttgct gcaaaatagt aaattagtag aaaaatgaag aaatttgtgc
     7321 ttatttgttt ttgtgtgctt tcttcggtag ggggatatgc tcagaactgg gatatcaata
     7381 cgttacataa aataaacagt cttgatagta agtttgcgag gaattatagc aaagcctttt
     7441 ctaaatcggc accttatatt gcggtaggtg taccggtggc gatggctgta tatgcaggta
     7501 tcgataaaga taaagagctg ctgaaagatg ccatttacat cggtacgagt gtggccgagg
     7561 cagtcgtgat tacgtatggt atgaaatatg cttttgaccg tgagcgtccc tacgaccgtt
     7621 atccggatcg ggtagatgca cgtagtcatg aatcgagtcc ttcgtttcct tccggtcata
     7681 cggcagcagc cttttcactg gctacttctt tgagtatccg ctatcctaaa tggtatgtga
     7741 tagctccatc tgctttctgg gcatgttctg tgggattctc aagaatgaat gaaggagtac
     7801 attacccgtc ggatgtagca gcaggagctg tgataggggc cggttgtgcg gtagccaata
     7861 tttatgtgaa tcgctggctt aacaagtggt tgttcggtga gaagaagaag gttacaataa
     7921 gttattgacg acatacggtg aatgacaaac aggctgcagg aagcatagtc tgttcgtcat
     7981 tcaccgtata tcgttttccg ttatagaaac gttatttcaa tatcttttcg tactctttgt
     8041 catttaagat ttccagtgcc cgctccacac tcttattggt ggcattcatt acttggaaat
     8101 attcattcat atcccataag tcacgggcta tcaaagcttt cagctgagct ttaatcagtg
     8161 gcagggcttt gttgtactgc tcctcgttga attcaatctt ttctttatcg gcagcttctc
     8221 tcaggtagtt caatagctgg tcatcgattt caaacttttc attgaatttc tcgaatgtct
     8281 tatatttatc caataaagcc tttcggttct tttcaatgaa gttcattgtg gttttaatga
     8341 ctactccttt ggctaccagg ttacggtgat agtcggtata cagcgttgtg tctaccggaa
     8401 cgaagtagtc cggcatgata cctcctccac cataaaccgt acgtcccagt tttttagtct
     8461 ggcatttcag tgagtccggg aagtggatgc tgtctgcact gaccatttcg ccatgattat
     8521 accggtcgat cagatcctgg ttgtattttt cgatgctgct ttcactgctt tttccttttc
     8581 ccgatttttc gttgatgctg ctgtcataag gcttttgtat gcaacgtcct gcaggtgtat
     8641 agtagcgggc aatggtcagg cggatcatag aaccgtccgg aaggtcgatc gggcgttgaa
     8701 ccagtccttt accgaaagaa cggcgtccta ccaccactcc tctgtcccaa tcctgaatgg
     8761 cacctgtcac aatctcactt gccgaagccg aatattcgtc taccaatacc accagacgtc
     8821 cgttacggaa gtttccgtta cctttggcaa aaaactcact gcgttgtgca gaacgtcctt
     8881 ctgtgtagac aatcagttct ttttgtccca ggaactcgtt tgccagatcg atggcggcat
     8941 tcagataacc tcctccgttg ccttgcaggt ccagaatcag atctttcatc ccttttttct
     9001 gcaactcttt cagggctttt agaaactctt cggcggtagt tgctccaaaa cggttgatac
     9061 ggatgtatcc tattttaggc tgaatcatat aagcggcatc caggctgagg attggaattt
     9121 tatctcgttt tacattaaat aaaagcggtt ctttcacacc tctgcggata atggtcaggt
     9181 ttactttcga atctttgggg ccccgcaggc gtcccatgat ttcttctgtt cccattttta
     9241 cgcctgctat ggctgtgtca ttcaccgcga tgatacggtc tcctgccagg atacctacct
     9301 tttcggacgg gccattactc accggttgta cgatgagcag cgtatcttcg atcatctgaa
     9361 actgtacacc tatcccttcg aaattgcctt ggagcggttc attcattttc ttcacctctt
     9421 cggcatccga ataggtggaa tgagggtcga gctgtgccag catttctatg atggccgatt
     9481 caaccagttt gttttcattg accgtatcta catataaatt agagatggcg aactctgcca
     9541 gttgtaattt tcgcatggcg ggtgagccaa agttctgtgc ctgtagtccc aaaacggaac
     9601 acaaaccgat aagcaggtat attattcttt tcatgatcac atgggtttat tacatttcca
     9661 tccctttggg aatgaacata ctgatatcct tattatagcc aagcagttcg cggacgatgg
     9721 tagagctgac acaggtcaat tccggttcgg taaataacag aatggtttca atgccggcca
     9781 gtttccggtt gatatcggca attgtttctt cgtattcgaa gtctttcacg gtacggatac
     9841 cgcgaacgat gaattgggca tctacctgac gggcaaagtc gatcgtcagg caatcgtaag
     9901 attcgacctt gatccggggt tcgtctttat agaacttacg aatcatttcc acacgtttct
     9961 cgatcggaaa gtatgtattc ttgttttcgt tgataccgat accgatgacc acttcgtcca
    10021 tgaatgtcag ggtgcgttga actacggagt agtgtccgat ggtaaacggg tcgaacgttc
    10081 ccggaaagat agctcttctc atgtttatgc gatgtcttct tctataacca gattatcaat
    10141 aataaagttt tgccgttcca ttgtattctt acccatgtaa aattcgagta gttcttttac
    10201 cgtgtctgtt ttgcgcagcg atacttgttc gagacgcata tctttgccga taaagtgtct
    10261 gaattcgtcg ggcgagattt cccccaaacc tttaaaacgg gtgatttccg gattcgggct
    10321 aagctcttta atagcattta cacgctcttc ttcggtataa caataaagcg ttttcttttt
    10381 attgcgtacg cggaagagag gagtttggag tatatataca tgtcctttct ttatcagatc
    10441 ggggaagaac tgaaggaaga aagtaatcag caacaagcgg atgtgcatac catccacatc
    10501 ggcatcggta gccacgatca ctttgttgta gcgtaagcct tcgataccgt cttctatatt
    10561 caatgcagct tgcagcagat tgaattcttc gttctcgtaa actacttttt tggtcaggcc
    10621 gaaagagttg agaggcttac cgcggaggct gaatacggct tgtgtgttca catcccggct
    10681 tttggtgata gagccgcttg ccgagtcacc ctcggtgatg aagatgcacg attcctcttc
    10741 cagccctttg cctttcacat cgttcaggtg gacgcggcaa tcacgcagct tccggttgtg
    10801 cagattggct ttcttggcgc gttcacgtgc cagtttggtc actccggcaa tggctttgcg
    10861 ttctttttcc gaatcctgta tcttttgcaa catgatttcg gctacatcgg catgtttgtg
    10921 gaggaaattg tctacctcct gttttatgaa gtcacccacg aacttattta ctgtgatgcc
    10981 tcccggcgac atattggtag agccgagttt gattttggtc tggctttcaa acataggttc
    11041 ttccacgttg acagcaatgg cggctaccag tccgttacgg atgtcagtat agtcttgatt
    11101 cttgttatag aactctttga tggtgcgggc gatgtgttct ttgaaagcac tttgatgggt
    11161 acctccctga gtggtatgct gaccgtttac aaatgagtag tactcctctc cgtactgtcc
    11221 ggtatgggta aaggctatct cgatatcttc gcccttcaga tgtacgatgg ggtagaggcc
    11281 ggtagctgtc atgttatcat tcagcaaatc taccaggcca ttgcgcgaaa ggatccgttg
    11341 gccattatag ataattgcca gcccggtgtt caggtatgtg taattgcgca gcatcgtctc
    11401 gataaattcg ggacggaaac tataattcag gaataaagtt tcatccggtt cgaagaagat
    11461 gtaagtaccg ttttcttctt ccgtatcttc tgtgtggtct gtcaccaact ctcctttggt
    11521 aaaggtggcg caacgcactt taccatcccg gtaactacgt acttcaaagt ttgagctcaa
    11581 agcattgaca gctttcacgc cgacaccgtt cagtccgaca cttttcttga aagccttgct
    11641 gtcatactta ccaccggtgt tcagcacact gactgcctct attagttttc cctgtgggat
    11701 accgcggccg tagtcgcgta cactgacacg aagattctct tccactctga tttcgatctt
    11761 cttgccggat tgcattttga actcgtcgat actgttgtca ataacttctt tcagaaggac
    11821 atatattccg tcttcgggat gcgaaccgtc gcccagctta ccgatgtaca tacccggacg
    11881 ggtgcgcaca tgttccatgt cgctcaggtg gcggatgttg tcgtctgtat attctacagg
    11941 gttgttgtct acaggtatca gttcgttctc ttccattgtt tttagtctat cttcttagta
    12001 aacgcacgac gacgtttatg ttgttcggtt ttaaagtatt cccattgtgc ctgaaccttt
    12061 ccgttcattt ccagttcggg gttgctttct gcaaagataa aacctaattt ttgataaacc
    12121 ggaattaaat cggaaaataa caaagcgtta acacctttgt tttggtactc cggtttcacg
    12181 gctacaagca gcaggtcaag cattttggcg cgtcgtttca tgaacaatgc ctttagcaga
    12241 taataccatc cgaggggcaa aaggcgtcca tgcgatttct gtaacgcttc cgaaagtgaa
    12301 ggcattgaaa tgcctacggc aattaacttg tcttccgcat ctgtgatcag ggttaccatt
    12361 cgcaagtcga caatcggaag gtacatttta acatattggt caatttgccg ttgcgaaagc
    12421 ggagagtatc cgtacagcgg actataagct tcgttcatca actcaaagat ggcttgtccg
    12481 taatcggctg caatctttct ggatgaggta tatttcttta tcttgaggtt atatttacgc
    12541 tgaataagat cggatatgcg ctggtgcttc tcagggatgg cgtcaggaat ataaattttg
    12601 tattccaccc agtcggcatc tttctcaaat cccagtttct ccatgtgttg cggatagtag
    12661 ggatgattgt agatggttgc catggtgctg agttggtcga atccttcgat cagcatacct
    12721 tctgcgtcga agtcggtaaa tccaagaggt ccctgaatgt tctccatccc tttggattta
    12781 ccccattctt ctacggtttg cagaagtctg gaagatactt caaggtcgtc gatgaagtcg
    12841 atccaaccga aacggacatc ttttttgttc caggtggcat tggcacggtg attgataata
    12901 cctgcgatgc gccctacgat ttttccgtct ttataagcca gaaagtactc ggcctcacag
    12961 aactcgaatg ccgcattttt cttcttattg aatgtattca gcatgtcgtc gtagaggtca
    13021 ggtacggaat aaggattctc tttgtataat tcgtaattaa aacgaatgaa ttttttaagt
    13081 tctctttttg tcgatacctt tttaattgta atggccatag cttgtattta tgatgagggg
    13141 gcaaagatac gtgataatct ttaaattacc acgtacgaaa actaaaaact atgtgtctcg
    13201 atgttatcaa atctgataga tcagataggt ggtgtaggct atatagcata acaccagaat
    13261 acttccttcg atccgtgtga tggtgcgttt ggcaaaaaat aatccgaaaa accagagcag
    13321 aatgcccgaa ccgaccaagg tgaaaaggtc gaagttattg atgcctgtca gccgcaaggg
    13381 agtgatggaa gcactgcatc ccaatacaaa gaagatgttg aacagattac tgccgatcac
    13441 attaccgatg gctatttccg gattcttttt caaggcagcc actatcgatg tagcaagttc
    13501 cggtagggag gtacctccgg ctaccagtgt gagtccgata acagattcgc tgacgccaag
    13561 gtgccgtgcg atgttgcttg ctccctctac aaaccattgt cccccgaaaa taagtccggc
    13621 caatccgccc agaatgaaaa gtacggattt ccacatcggg aggcttttga tttcctcttc
    13681 cggttgagta ttgtttgtgg gtgaggctat ggcaaatgtg tagcccagga agatggtgaa
    13741 gaaacagagc agaatcagtc cgtccgagat gcttagtatg ttgctggaag ctttattcag
    13801 aaaaacgtca ttggcgcata tcagcaggac gatggaggag agaatgcata gcggaatctc
    13861 tttccgcaaa gtattccggg taattacgat aggagcaaat agagcggtgc acccgacgat
    13921 catcaatgta ttgaagatat tacttcccac tacgttacct acggcgatgt ccgcgctacc
    13981 tttcagggcg gacgatacgc taacggtcag ttccggggcg gaagttccga aagctacgat
    14041 agtcaggccg attacgatgg aaggaatacg gaatcgcttg gctacggacg cagcaccatc
    14101 tgtcaggcag ttggcaccta tcaaaatgag gagtaatcct ccaataagca gtaatatatc
    14161 catgtctata cctttaaatt acggattcgg gtgcaaatat aatgatttcg atctatgcta
    14221 tgtcaaaaac aatctgtatg tttggcacgt ttatccattc cggtgacaat tactttatga
    14281 gtttttgata tgaaaaagaa cagattattc ggccttttgt tgtttctgtt ggtgaccaac
    14341 aatatgtgcg cacagttggg aaaggcggtt cgtgagatat tgacgggtga tagtgtggct
    14401 acccggaccg cagttcggaa cgattcggat tccgtacgga tggcagatat gaagaaagag
    14461 ctggaggagg cgcgtctgag cgaagccaat atgcgtatgg aaatggagca gatgaggctg
    14521 aaagcttttg ctgccgactc tgtgaaatta gctcaacaaa gggcacgtat cgactcactt
    14581 cgccagttta cgccgggagt accggtagtg gtcgaaggcg atacattgtt ttatttgtat
    14641 accaagcgtg ggggatatac ccctttgcag cgggccgaaa tgatcgatgc ggccatcatg
    14701 cagttgggta aacggtttac cctgcatccc gattctgtct atatcgagag cagcgatatc
    14761 gtaaccgatc tgatgtacgg caataaagtc attgcttcgt ttaccgacca ggacggacta
    14821 tgggaaggac gttcgcgcga gcagttggca acggataagc ggaagattgt agtacagaaa
    14881 ctgaaagagt tgaaggagga gcatagcttg tggcaactgg gtaagcgtat tctgtatttt
    14941 gtcctggtat tggcagggca gtatctgttg ttttggctta caggctggct gttccgtaaa
    15001 ctgaaagtac gtatccaaaa gctgaaggat accaggctga agccgatctc cattcagaat
    15061 tacgagttat tggatacgca gcggcaggtc aacctgttga tcttcctttc caatttgctg
    15121 cgctatgtaa tcatgcttct ccaattgttg attaccatcc cccttttgtt cgctatcttc
    15181 ccacagacca aggggctggc ctatcagata ttttcgtata tctggaaccc gatcaagaac
    15241 atactggtag gtatagtcga ttatattccc aatttgtttg ccattcttat catctgtttt
    15301 gccgttaagt atctggtgcg cttggttcac tacttgtccc gtgaggtaga ggcggggcgg
    15361 ctcaagttcg gtggcttcta tcccgactgg gcaatgccta cttatcatat catccgtttt
    15421 ctgctttatg cttttatgat tgcgatgatc tatccctatt tgccgggggc taaaagtggg
    15481 gtatttcaag gaatctcggt tttcatcgga ttgatcgttt ctttaggatc cagcacggta
    15541 atcggtaatg tgattgcggg gctggtcatt acttatatgc gtccttttaa ac
//
