Select genomic region:
Overview
18.1
27.1
42.1
49.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaPMJDBAPL_45 (original name was: gnl|Prokka|PMJDBAPL_45)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 18.1 | RiPP-like | 2,238 | 17,918 | gassericin T | RiPP | 22%

gnlProkkaPMJDBAPL_54 (original name was: gnl|Prokka|PMJDBAPL_54)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 27.1 | lanthipeptide-class-ii,RiPP-like | 1 | 17,973 |

gnlProkkaPMJDBAPL_71 (original name was: gnl|Prokka|PMJDBAPL_71)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 42.1 | RiPP-like | 61,949 | 74,099 |

gnlProkkaPMJDBAPL_87 (original name was: gnl|Prokka|PMJDBAPL_87)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 49.1 | T3PKS | 11,564 | 52,721 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 18.1 | RiPP-like | 2,238 | 17,918 | gassericin T | RiPP | 22%
Region 27.1 | lanthipeptide-class-ii,RiPP-like | 1 | 17,973 |
Region 42.1 | RiPP-like | 61,949 | 74,099 |
Region 49.1 | T3PKS | 11,564 | 52,721 |

No secondary metabolite regions were found in these records:
  gnlProkkaPMJDBAPL_2 (original name was: gnl|Prokka|PMJDBAPL_2)
  gnlProkkaPMJDBAPL_11 (original name was: gnl|Prokka|PMJDBAPL_11)
  gnlProkkaPMJDBAPL_18 (original name was: gnl|Prokka|PMJDBAPL_18)
  gnlProkkaPMJDBAPL_25 (original name was: gnl|Prokka|PMJDBAPL_25)
  gnlProkkaPMJDBAPL_26 (original name was: gnl|Prokka|PMJDBAPL_26)
  gnlProkkaPMJDBAPL_30 (original name was: gnl|Prokka|PMJDBAPL_30)
  gnlProkkaPMJDBAPL_33 (original name was: gnl|Prokka|PMJDBAPL_33)
  gnlProkkaPMJDBAPL_34 (original name was: gnl|Prokka|PMJDBAPL_34)
  gnlProkkaPMJDBAPL_36 (original name was: gnl|Prokka|PMJDBAPL_36)
  gnlProkkaPMJDBAPL_37 (original name was: gnl|Prokka|PMJDBAPL_37)
  gnlProkkaPMJDBAPL_38 (original name was: gnl|Prokka|PMJDBAPL_38)
  gnlProkkaPMJDBAPL_39 (original name was: gnl|Prokka|PMJDBAPL_39)
  gnlProkkaPMJDBAPL_40 (original name was: gnl|Prokka|PMJDBAPL_40)
  gnlProkkaPMJDBAPL_41 (original name was: gnl|Prokka|PMJDBAPL_41)
  gnlProkkaPMJDBAPL_42 (original name was: gnl|Prokka|PMJDBAPL_42)
  gnlProkkaPMJDBAPL_43 (original name was: gnl|Prokka|PMJDBAPL_43)
  gnlProkkaPMJDBAPL_44 (original name was: gnl|Prokka|PMJDBAPL_44)
  gnlProkkaPMJDBAPL_46 (original name was: gnl|Prokka|PMJDBAPL_46)
  gnlProkkaPMJDBAPL_47 (original name was: gnl|Prokka|PMJDBAPL_47)
  gnlProkkaPMJDBAPL_48 (original name was: gnl|Prokka|PMJDBAPL_48)
  gnlProkkaPMJDBAPL_49 (original name was: gnl|Prokka|PMJDBAPL_49)
  gnlProkkaPMJDBAPL_50 (original name was: gnl|Prokka|PMJDBAPL_50)
  gnlProkkaPMJDBAPL_51 (original name was: gnl|Prokka|PMJDBAPL_51)
  gnlProkkaPMJDBAPL_52 (original name was: gnl|Prokka|PMJDBAPL_52)
  gnlProkkaPMJDBAPL_53 (original name was: gnl|Prokka|PMJDBAPL_53)
  gnlProkkaPMJDBAPL_55 (original name was: gnl|Prokka|PMJDBAPL_55)
  gnlProkkaPMJDBAPL_56 (original name was: gnl|Prokka|PMJDBAPL_56)
  gnlProkkaPMJDBAPL_58 (original name was: gnl|Prokka|PMJDBAPL_58)
  gnlProkkaPMJDBAPL_59 (original name was: gnl|Prokka|PMJDBAPL_59)
  gnlProkkaPMJDBAPL_60 (original name was: gnl|Prokka|PMJDBAPL_60)
  gnlProkkaPMJDBAPL_61 (original name was: gnl|Prokka|PMJDBAPL_61)
  gnlProkkaPMJDBAPL_62 (original name was: gnl|Prokka|PMJDBAPL_62)
  gnlProkkaPMJDBAPL_63 (original name was: gnl|Prokka|PMJDBAPL_63)
  gnlProkkaPMJDBAPL_64 (original name was: gnl|Prokka|PMJDBAPL_64)
  gnlProkkaPMJDBAPL_65 (original name was: gnl|Prokka|PMJDBAPL_65)
  gnlProkkaPMJDBAPL_66 (original name was: gnl|Prokka|PMJDBAPL_66)
  gnlProkkaPMJDBAPL_67 (original name was: gnl|Prokka|PMJDBAPL_67)
  gnlProkkaPMJDBAPL_69 (original name was: gnl|Prokka|PMJDBAPL_69)
  gnlProkkaPMJDBAPL_70 (original name was: gnl|Prokka|PMJDBAPL_70)
  gnlProkkaPMJDBAPL_72 (original name was: gnl|Prokka|PMJDBAPL_72)
  gnlProkkaPMJDBAPL_73 (original name was: gnl|Prokka|PMJDBAPL_73)
  gnlProkkaPMJDBAPL_74 (original name was: gnl|Prokka|PMJDBAPL_74)
  gnlProkkaPMJDBAPL_75 (original name was: gnl|Prokka|PMJDBAPL_75)
  gnlProkkaPMJDBAPL_76 (original name was: gnl|Prokka|PMJDBAPL_76)
  gnlProkkaPMJDBAPL_86 (original name was: gnl|Prokka|PMJDBAPL_86)
  gnlProkkaPMJDBAPL_96 (original name was: gnl|Prokka|PMJDBAPL_96)
  gnlProkkaPMJDBAPL_97 (original name was: gnl|Prokka|PMJDBAPL_97)
  gnlProkkaPMJDBAPL_103 (original name was: gnl|Prokka|PMJDBAPL_103)
  gnlProkkaPMJDBAPL_115 (original name was: gnl|Prokka|PMJDBAPL_115)
  gnlProkkaPMJDBAPL_131 (original name was: gnl|Prokka|PMJDBAPL_131)
  gnlProkkaPMJDBAPL_136 (original name was: gnl|Prokka|PMJDBAPL_136)
  gnlProkkaPMJDBAPL_137 (original name was: gnl|Prokka|PMJDBAPL_137)
  gnlProkkaPMJDBAPL_141 (original name was: gnl|Prokka|PMJDBAPL_141)
  gnlProkkaPMJDBAPL_142 (original name was: gnl|Prokka|PMJDBAPL_142)
  gnlProkkaPMJDBAPL_157 (original name was: gnl|Prokka|PMJDBAPL_157)
  gnlProkkaPMJDBAPL_160 (original name was: gnl|Prokka|PMJDBAPL_160)
  gnlProkkaPMJDBAPL_161 (original name was: gnl|Prokka|PMJDBAPL_161)
  gnlProkkaPMJDBAPL_166 (original name was: gnl|Prokka|PMJDBAPL_166)

Compact view
gnlProkkaPMJDBAPL_45 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,238 - 17,918 nt. (total: 15,681 nt) Show pHMM detection rules used
Region on contig edge.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaPMJDBAPL_54 - Region 1 - RiPP-like,lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 17,973 nt. (total: 17,973 nt) Show pHMM detection rules used
Region on contig edge.
lanthipeptide-class-ii: cds(LANC_like and DUF4135)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg27_12

ctg27_10
Leader:
MSNKDLNNIVGG
Core:
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S A A A G G A Y T W K K H H
Core with dehydrations:
A F E E M Dha I Q Q M Dhb E I Q G L G V Dhb Q V Q Dha Dhb P Dhb V A I Dha R A G I A A Dha R A Dha Dha V R Cys A R W V Dha A A A G G A Y Dhb W K K H H

#### MIBiG 3.1 matches for ctg27_10

8.1% BGC0000582 (ADR72962.1): Linaridin: cypemycin
23
S T P T V A
28
+T P T V A
4
A T P T V A
9

#### antiSMASH-DB 4.0 matches for ctg27_10

40.3% NZ_CP045729.1: Lanthipeptides: allorf_1568662_1568871_lanthipeptide
11
T E I Q G L G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S A A A G G A Y T W K K H H
62
T I Q G G Q++P + I S+A S S V R C A+W V S A +G +W K H H
1
T S I Q G N G A E S A Q T S P L I P I S K A-------S S V R C A K W V S A I S G--L S W A K H H
43
30.6% NZ_CP045729.1: Lanthipeptides: LG045_RS07910_lanthipeptide
17
G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S A A A G G A Y T W K
59
G Q S T P A I S R ++ +R S S +C W+S +A G G ++K
1
G T E T A Q S T P--A I S R V T L S I A R K S S A K C I S W I S F S A G G L N S Y K
41
22.6% NZ_FPCC01000026.1: Lanthipeptides: BM377_RS12925_lanthipeptide
1
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C
44
A F E E+ + M ++Q G G + ++T +++ A A++ S S +C
1
A F E E L D V D D M Q Q V Q G A G D V E A E T T V P L S V V I A T A A S A I Y S S K K C
44
with 8 more sequence matches
22.6% NZ_KB976303.1 and 1 other:
NZ_KB976303.1 Lanthipeptides: IGY_RS26035_lanthipeptide
Lanthipeptides: IGY_RS26045_lanthipeptide
25
P T V A I S R A G I A A S R A S S V R C A R W V S A A A G
53
P T V I S R A S S C V S A +G
9
P T V------I V V S R A S S K A C M S G V S A I S G
31
21.0% NZ_KN125582.1: Lanthipeptides: DJ91_RS27550_lanthipeptide
25
P T V A I S R A G I A A S R A S S V R C A R W V S A A A G
53
P T V I S R S S +C A +S A +G
9
P T V------I V V S R I S S A K C A S T I S A I S G
31
17.7% NZ_FPCC01000026.1: Lanthipeptides: BM377_RS12915_lanthipeptide
1
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V A I S R A
32
A+E+++ + M Q G G T+ + T ++A I+ A
1
A Y E D L N T E D M Q N T Q G A G D T E A E-T V S L A I T G A
31
16.1% NZ_CP031746.1: Lanthipeptides: allorf_1813979_1814164_lanthipeptide
42
V R C A R W V S A A---A G G A Y T W K K
60
V C A R W V + A G T W+
5
V G C A R W V P C S L L G A G C P V T W R P
26
14.5% NZ_LT800494.1: Lanthipeptides: B7E07_RS02625_lanthipeptide
17
G V T Q V Q S T P T V A I S R A G I A A
36
G V + Q+T P T+A++ A + A
2
G V A E P Q A T P T I A L T S A L V G A
21
12.9% NZ_CP094681.1: Lanthipeptides: K5I26_RS05295_lanthipeptide
20
Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S
49
+V Q V G I R ++ C A +++
6
E V Q E A Q K V C C P D K G I E R G R T T T S D C A L F L T
35
12.9% NZ_FPCC01000026.1: Lanthipeptides: BM377_RS12905_lanthipeptide
1
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V
27
+F E+++ + M Q G G ++T P +
1
S F E D L N T E D M Q N T Q G A G D V D A E T T P V I
27
12.9% NZ_PVMZ01000043.1 and 1 other:
NZ_PVMZ01000043.1 Lanthipeptides: CLV67_RS49775_lanthipeptide
Lanthipeptides: CLV67_RS49775_lanthipeptide
39
A S S V R C A R W V S A A A G G
54
+S S R C A ++ A G G
1
S S S T R C A E S I A R A T G G
16
ctg27_22
Leader:
MATSQQEVALKGS
Core:
R E R C N L S L Q A I R V S Q L T K L M C T R S K L L A N A N K C Y N L K
Core with dehydrations:
R E R Cys N L Dha L Q A I R V Dha Q L Dhb K L M Cys Dhb R Dha K L L A N A N K Cys Y N L K

#### antiSMASH-DB 4.0 matches for ctg27_22

20.5% NZ_CP020327.1: Lanthipeptides: B5S25_RS25065_lanthipeptide
15
Q L T K L M C T R S K L L A N A N K C Y N L
36
+L T K++ + +L+ N K Y L
3
K L T K V L R R Q H R L V I N K K K V Y R L
24
18.9% NZ_AP018268.1: Lanthipeptides: CDC39_RS06790_lanthipeptide
17
T K L M C T R S K L L A N A N K
32
T ++C R + N A N K
7
T P I I C L R Y T M F R N A N K
22
18.9% NZ_JALMDK010000007.1: Lanthipeptides: MZC64_RS28180_lanthipeptide
13
V S Q L T K L M C T R S K L L A
28
S +T+L C T R+ L +
3
T S V I T R L A C T R T P L C S
18

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg27_10 - Class II
  Cleavage pHMM score: -0.90
  RODEO score: 0
  Monoisotopic mass: 6370.3 Da
  Molecular weight: 6374.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    6392.2 Da N = 1
    6410.2 Da N = 2
    6428.2 Da N = 3
    6446.2 Da N = 4
    6464.3 Da N = 5
    6482.3 Da N = 6
    6500.3 Da N = 7
    6518.3 Da N = 8
    6536.3 Da N = 9
    6554.4 Da N = 10
    6572.4 Da N = 11
ctg27_22 - Class II
  Cleavage pHMM score: -7.10
  RODEO score: 0
  Monoisotopic mass: 4189.3 Da
  Molecular weight: 4192.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4210.0 Da N = 1
    4228.0 Da N = 2

gnlProkkaPMJDBAPL_71 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 61,949 - 74,099 nt. (total: 12,151 nt) Show pHMM detection rules used
Region on contig edge.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaPMJDBAPL_87 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 11,564 - 52,721 nt. (total: 41,158 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.