LOCUS       c00022_gnlPro..        15875 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNHEIFGG_79.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 13:59:20
            Original ID  :: gnl|Prokka|HNHEIFGG_79
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15875
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15875
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2758:5875]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2759..5875
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15875
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15875
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             669..1184
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACARSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1352..2341)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MRMLEKIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVSLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARFLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2759..5017
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_3"
                     /sec_met_domain="Gly_radical (E-value: 6.1e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.1e-245, bitscore:
                     809.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHATDSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             5054..5875
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="Radical_SAM (E-value: 9.8e-27, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             complement(6100..6411)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 67.1; E-value: 3.9e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="FeS_assembly_P (E-value: 1.6e-20,
                     bitscore: 67.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAEGTAEIT
                     MTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARMELGIHS"
     CDS             7472..8392
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8562..9086
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTPNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(9181..9426)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_8"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00053, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRPDK"
     CDS             9599..10027
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(10130..10771)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 6.4e-19, bitscore:
                     63.0, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLATVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAVRYQAIPEDADFIAVFGGVNDYGRDQPLGQYGDCDMTTFYGA
                     LMMLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPAQAAIYSVDTLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(11787..13454)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 410.4; E-value: 2.8e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_11"
                     /sec_met_domain="BCCT (E-value: 1.2e-124, bitscore: 410.4,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 ttatgcggta ttagcatctg tttccaggtg ttatcccccg cttctgggca ggtttcccac
       61 gtgttactca ccagttcgcc actcactcaa atgtaaatca tgatgcaagc accaatcaat
      121 accagagttc gttcgacttg catgtattag gcacgccgcc agcgttcgtc ctgagccagg
      181 atcaaactct caaattaatg atgagttcta aaaagctcat ttaatgttgt actaaaattt
      241 atttgctagc gaattgactt cgcaaatgtt ttgctcttga ttcaaaatca agagacccta
      301 cacatttgat tcgtcgaaac tttgttcagt tttcaaagat ctaattccgt gtgttaatcg
      361 cttaacacaa cttaatcatc ataacatctt aatcaatatc ttgtcaacaa ctttttttaa
      421 gaagtaactt gattaatttg tcatagttgc cgttgcgaca acagaaacta tcttaccaat
      481 tactgaagaa attgtcaaca actaatttca ataattattt ggtggtgaga tgcatctgcc
      541 gtagcagcaa cgtttactaa tataccaatt gaagtaaaaa gtgtcaacac tttttctgaa
      601 tttcttttta ttaatagtca aaccagcttt ctttctctat actatttaat taaaggagcg
      661 actaaattat gctagcttgg ctaccattct ttttgatttc attaatgttt attgttctac
      721 tatacgcttg tgcgcgatca gcgcgcacaa atatccagcg ttttaagcaa ctcagtttaa
      781 ttgcctttct ctgggtctta actgcttttt gctatacacc taccagttac aattttggta
      841 cccaactcgt tattcaatat attcaatggg gacccgttaa gctgaacgtg attcctttcc
      901 aacaacttga cattgaattt tggctcaacg ttctcctcac tgttccattg ggcggtttac
      961 tggcatggaa ttttcccgac ttgccttggc gtcgttttat ttggttggga tttcttacgg
     1021 ggctaacact cgagctggga caattcatcc ttgactggtt ggttaacctc aaacgttggg
     1081 ttgatatcga tgatgtcatc acaaattggg ctggtgtcat tatcggtgcc gctggttata
     1141 aaattgcacg tcatgttccc ggacttcgct ggttgcaaaa ataacgtata tatagaagca
     1201 aaaagcaaaa tagcgtttgt ttagcaccca caagtgccaa acacttcagc ggtctagctg
     1261 tcatgaaatc gtaattaaat aagcgtcgca gccttaagtg gctgcgacgc ttatttaatt
     1321 taactactaa ctattaatga agctgccatc atcaggattc aaaaaacaga tcgaatactc
     1381 gcttacgatc ttggttccag acctgattgt cactagttgg ataaactcga tttgttaaca
     1441 caaccagccc aatttgacga tccaaatcaa aagcaactgc cgggccagta aaaccagtat
     1501 ggaaatattg atgtcgtccc gcacgtcgtt cccaacctaa cgtccggcca ttttcgtcat
     1561 actcgcctaa ccagtcaaag acattttcat ccagcacccg tttgccttga tattcaccaa
     1621 agtttaacat catttcaata aatacggata aatccgtcag cgttgagaac aagcctgcat
     1681 gaccactctc accattcaac aaaaaggctt tataatcatg cacctgtcct tgaatctgac
     1741 cccgccgcgg atcaaactcc gtcggcacaa accgaatctt cggacgattt aagttataac
     1801 ccgtattggt catcgctagt ggatagcaaa cgtggtcttg aatactccga gccaatgagc
     1861 cgtcaaccgc acgaataatc catcccaata aaataaatcc caggtctgaa tagacatacg
     1921 ttgtccctgg tgccgtgacg agtggcgcat cataaaccgc tttgatcaga tcttcacgtt
     1981 gcatcttatc caggttatca atatctgccg gtagcccact attatgaagt aacaagtttt
     2041 taatcgttat ttcaggatga gtgaacccag gtaaaaaccg ggcaaccgag tccgttaaat
     2101 gaatcgtgtg gtccgataac aactgaaaaa tcctcgtcgt ggtccctaca accttagtta
     2161 ccgatgctag gtcataaatc atcgcaggat ctaagctcac ggcaaactca tcgcggccct
     2221 gcttaccatg atagtattga ttgatacctt taggggtgat caagctaaac gacgccccat
     2281 aaatgtcgcc agcttcaata caactgtcaa tatattgttc aattttttcg agcatccgca
     2341 ttacgcccac ctttcactac attcactagt ttctgcttat cttctttatg ataacgaact
     2401 tcctcataaa atcaacggca aacgctttta acaccctcca cacctcgttg cactttttat
     2461 taattaacta gttaaacact tgttacatta tggacaatat tccacttata tatcaaaaca
     2521 agtcttgttt ttagccgttt tctaaatata attaagtgaa ttaccaatgc ctatctagct
     2581 atgtaagtac tgttatatca acgttaatag tcaacttttc aataatagat tgcaaaaaaa
     2641 taacccaaac gtgaaataaa tcacctgaaa gcggttacaa atccagcaaa aaatgttatg
     2701 attcaaatat agaattttat caatcatttg attggattca aattatggag gcgagaaaat
     2761 gattacatca gaaaagacaa caaaaccagc agcttggaaa ggtttcaaag gcgggcactg
     2821 gcaggaagaa atcaacattc gtgattttat tcaaaataac ttcacacagt acaatggcga
     2881 cgaaagcttc ctggccggac caacagccgc tactaagacc ttgaatgaca aagtcttaga
     2941 attaaagaaa caagaacgtg ccgctggtgg tgtgttggat gctgatacta aagtcgttgc
     3001 aacgattact tcacacggcc ctggttatat tcaaaaagat ctcgaaaaga ttgttggtct
     3061 ccagactgac aagcctttga agcgggcctt catgccattt ggtggtattc gaatggctga
     3121 tgacgctttg aaatcatacg gttatacccc tgatgaagaa aacgacaaga ttttcactga
     3181 atatcgcaag actcataacc aaggcgtctt cgacgtttat actcctgaca tgcggaaagc
     3241 acgtcactac aagatcatca ccggactacc agatgcatac gcacgtggcc gtctcattcc
     3301 tgatcttcca cgggtcgctg tttatgggat cgatcgttta atggaagaca aagctaatga
     3361 ctttgcccac attggtgatg gtgaattgac tgatgatgtt attcgcctcc gtgaagaagt
     3421 tcaagatcaa taccgtgctt tagcagatat gaagaagatg gctgccagtt atggctacga
     3481 tattagcaag cctgcaacta atgctcaaga agctattcaa tggatgtact tcgcttactt
     3541 agctgctatc aagacccaaa acggtgctgc aatgtccgtt ggccggattg atacaacgat
     3601 ggacatcttc atccaacgtg acttggacaa tggtgttctg gacgaaagcc aagctcaaga
     3661 attaattgat caattcgtca tgaaactacg gatggttcgg ttcatccgta ctgaagaata
     3721 caattctctc ttctctggtg acccaatctg ggcaacctta tcaatgtgtg gtttaggcgt
     3781 cgacggtcaa caccatgtga ctaagaccgc tttccggatc ttaaagactt tggacaacat
     3841 gggcgccgca ccagaaccaa acatcacgat tttatggtca gaccgcttac cagaagactt
     3901 caaacgttac gcaactgaag tttcaatcga cagttcaacc attcagtatg aaaatgatga
     3961 cttgatgcgg gtacaatggg gtaccgatta ttatggtatt gcttgctgtg tttccgcaca
     4021 accaattgct gatggaatcc agtacttcgg tgcccgggca aacttagcca aagcgattct
     4081 ttatgccatc aatggtggcc gcgacgaaat tgctggagat caagttggcc ctgcttacga
     4141 accaattact tcagaataca tcgattacga cgaattcatg aagaaattag acaagcaaat
     4201 ggattggtta gctgacactt acgttaactc actgaatgca attcattata tgcatgataa
     4261 gtactactat gaagctgccc aattagcttt gaagaatact gatcttgatc ggacctttgc
     4321 aactgggatt tctggcttat cacatgccac ggattcaatc tcagctatca agtatggtca
     4381 cgttaaagta attcgtgacg aacgtggtat cgccgttgac ttcaaagccg acaatgacta
     4441 cccacgttat gggaacaatg acgatcgcgc tgatgacatt gctaaatggt tagtcaaaga
     4501 attatacagc aagatgaaca cgcatcacct ctatcggaat gccaaacttt caacttctgt
     4561 tttgacgatt acttccaacg ttgtgtatgg taagaacact ggtaccacac caaatggccg
     4621 tcaaaaaggc gaaccattct caccaggtgc taaccctgca tacggtgctg aaaagagtgg
     4681 tgcattagct tcacttcttt caactgcaaa attaccatac cgttacgcaa ctgacgggat
     4741 ttccaacacg ttcggcgtta cccctaacac gttaggccat gacctcgaat cacggaaaga
     4801 cacgttagta aacatgttag acggttacat gaagaacgat gggatgcact tgaacatcaa
     4861 cgtcttcaat aaagacactt tgattgatgc tcagaaacac cctgaagaat acccaacatt
     4921 aacggttcgg gtttctggct actgtgtcta cttcgcagat ttaaccaagg aacaacaaga
     4981 tgacgttatt tcacggacat tcttcgaatc aatgtaacat ttaatcttta atagttaaga
     5041 aggcgaaagg ctcatggaaa acaaacaagt ttcaacaacg caagcggcgg caaaggagcc
     5101 tttgataggc tacgttcact ccatcgaaac gtttggctcc gttgacggac caggtatccg
     5161 ttacgtggca ttccttcaag gatgccacat gcgttgccaa tactgtcaca accctgatac
     5221 ttggaaactc aacgttggcg atcaaatgac ggccgacgag attctcgaag acgcggctaa
     5281 ataccgggct ttctggggca agacgggtgg catcacagtc agtggtggtg aatcactggt
     5341 acaaatcgac ttcatcttag acttattcga aaaagccaag gcgatgaata tcagtacttg
     5401 tctggatacc tctggacagc cttttacccg agaacaacct ttctttgaca agttcgaacg
     5461 tctaatgaag gtcacggaca tttcgttggt cgacattaag cacatcgatt ctgccaaaca
     5521 caagcagttg acccagtatg ggaacgaaaa tatcttggat atgattcagt acatggccca
     5581 acaccacgat gatatgtgga ttcgtcacgt cctggttccc caacggactg attacgatga
     5641 agacttgaag aaactcggcg attacattgc taagattcca aacgacgtcg ttcaaaaagt
     5701 cgaagtattg ccgtaccata ctttgggcgt taaaaaatat catgaaatga agatcaagta
     5761 ccggcttgaa ggaatcgagt ctccaaccca agatcgggtg gcaaatgccg aaaaactact
     5821 gcacaccgct gattacaacg ggtacaagac atggatgcca ttgccaaaac tttaaatcgg
     5881 catttctagc atgactaaaa caccagcgat acaatcgtct acggatggtt gtgtcactgg
     5941 tgtttttttg ctggctcgac gcatgcacgt attgctggct ggaattagta cagtggcacg
     6001 caaaaaaggc gccgcaagcc taaaccagca acgtctttcc ttaatcatcc cctatccaat
     6061 gaccgtcagc ccttgaacta gctgcgaaca ggccggccac taactatgaa tgcctagttc
     6121 cattcgagct tcgcgggaca tcatactttc gttccaagca ggttcccaca caatctcaat
     6181 ctcgatattg ttaacttctg gtaatttgat cagttcatcg tgaatgtcct tagccaacca
     6241 ttcggtcaaa ggacagcccg caatggtcaa cgtcatggta atttcagcgg tcccctccgc
     6301 cgtcaattgt gcatcataga tcaaccccaa gttaactaga tcaattccta attcagggtc
     6361 aatgacatgt cctagcgcct cgaaggcccg gtctttaaac gttgttgtca tcgtatctcg
     6421 tccttccata ccagcttgaa ttcactgatt aatcacgcca acgtttcgcg gtataagtgc
     6481 caccacactt gatacacgtc atcgttatat aaagcgcttt cttgtctact tctattgtac
     6541 cgtatgtcag cccatattca atcaattatt agcgctaatt agccgacttt tcaaacgatc
     6601 ggtcaatcag caaattatgc gactatttct cgaaaaaatt tactataatc cccgatatag
     6661 cagcgttttg agtcactatt gatttttatt gcgaattcgc ggttgttttt gttgtaagcg
     6721 tttgcggttt atgctattat actaagtgag gaaaggaatt aatcctcgat tagcaaagct
     6781 tctcaaaaga gtttggctgt cgctgtaatg ttagacagct agtatcacag tttgggtcgt
     6841 tatcgaaacc gttttaagcg ccgtgaagcg ttatcggtct agcgagtgtc gtgagattta
     6901 cgttggatga ctgaacgttg acccttagat aaacgataac cgcaaagaat taattggcat
     6961 tagaatgacg aacagatttt aactaagttt tagttggaaa caggtgtctc cgatgaccag
     7021 ttgttagttc cacattacca gttccatttg tagactcagg tattacaaag tttaaacgga
     7081 ggtgcatgtc tgttacgaag acattcccaa gttttaaacg cgagtttgac tttcgttaaa
     7141 acccgtctaa cgagtcgcaa tcaagtaaca accttacttt agatcgacta tagcagatag
     7201 ttacaataaa tacgggttag tccgttagaa gttggacacg cgtaaaattg aatagcatga
     7261 aggtgtatca tattaacact gaacaatttt tcattgctaa tcaggattat tcctcataag
     7321 tagaactcaa gtagagaagc cttgggttct attttttttg ctctaaaatc agatttacca
     7381 acagtcggca ccagacgtaa ccgtttacat cctcttacga aaaccgtata ctgaatttaa
     7441 atcaagttgc acattgagga ggactttagt tttgaaaacg attaatttag gtcacagcaa
     7501 tattcaagct tccagcgtgg cgcttggcat catgcgcatg gacgccttgg atgtcgctca
     7561 agccaccaag gttatcgata ccgctgctga tttaggcatc aattacgttg attcagctga
     7621 tatctacggt ggtggtcaat catcgaccat cttcggtcaa gcactcaagc aggctcacgt
     7681 atcgcgtgat cagctctata ttcagtcaaa aggcggcatt gttcctggca agcgttacga
     7741 cttttccaaa cagcacatac tggcagccgt ggatggcgag cttcaacgct taggtgttga
     7801 ttatctcgac accttcctcc tccatcgacc ggacgccctg atggaacccg aagaagttgc
     7861 tgccgctttt gacaagttgc aaactagcgg caaggtgcgc cactttggcg tctctaactt
     7921 caatcccatg caagttgaca tgcttcaagc ggcactaaac caacggctca tcatcaacca
     7981 actccaattt ggtatcatgc ataccggtgc gatcgacttt ggcttgcaca cgaacatgca
     8041 ggacgaacgt agtcttaacc acgacggcga gatgatcgaa tactcacggc tccataagat
     8101 gacgattcaa gcttggtcgc cttatcaata cggtaacttc gcgggtatct tcttagacaa
     8161 tccgaagttt ccagaactta ataatgccat gcaagcactc gccgatgaga aacaggtcac
     8221 taaatcagct attgcgaccg catggattct ccggcaccca gcccacttcc aagtcgtcct
     8281 tggtacgatg aatccggaac atctagctca aaatgctgct ggagcagacg ttacgctttc
     8341 tcggcaagaa tggtacgaca tttactttgc agctggcaac gatttacctt aatcacgatc
     8401 gacctaacag aattgacgat tagtttttac aatcaaaacg acgaccccaa atcaggattg
     8461 attttcaggt cgtcgttttt tagacgtttc actaacattt ttgatgtact caccacatct
     8521 acgcgtatac ttaatcttat caagactcag gaggcgagcg aatgacatcc acttgcacga
     8581 tctgtgaacg aatcaaacta attcaggcac atcagaatcc ttatttcgtt tacgaactca
     8641 caacgggcta cgtggtcctt gctgatagcc agtactttga aggctacacg ctctttttag
     8701 ccaaacatca cgttaccgaa ttacatcatt taccggcaca cgagaagtta cgataccttg
     8761 aagagatgag tatcgtccag gaagcttgtg cgcaggcctt tcatgcagac aaaatgaaca
     8821 ttgaactact cgggaatggt gacgcgcatg ttcattggca cttatttcct cgccataacg
     8881 gtgatacgcc caaccccggt cccgtctggt ggacaccgct ggaaacaatt tatggtgatg
     8941 atgtcagtct agacattccc cgtttaagcc ggttgaagcg cacgctcagc gtagcaattg
     9001 aggccacgct taatgctcgg gaagcagaat tgcaggcttt agaggcactc acaaggcctg
     9061 ctagccacag aattgacagc aattagacca aatcaggacc cagacccgct tagatcttgg
     9121 tggctacacc ccaattctta atcgcaattc gtcaccgtat ttcaaattgc caaaatccac
     9181 ctatttatcc ggccgactat catacgctcg cttagattta tagccagctc gaaaaaccgt
     9241 cttcataact tcaatgtgcc gttccttagt tgcttgtgcc ttagttccaa aaataaagcg
     9301 ggcccattcg cgctgataac caggtgtcaa agccacaaag aacgtttgca attcagcatc
     9361 aaccgctaac aattcggtta ccgccggaat atttttttca aatgaactga ggggtgctgt
     9421 actcataatc aaacctccga ttagttttac ttaaatttac tgtaagaaag ggaaaatccc
     9481 taattttcag gtttttatat ttcgaatttt cataaaattg cgctatcatt atagtataag
     9541 tattattatt tgactactat aattaaccat actgctattc accaagggga gccctgctat
     9601 gccaaaattt gatatcaccc tcatcagtcc cgaacgcgct aaagcgatgt tgactgaata
     9661 taaagaacaa cgtaagaact ctgtcccaca tctggcccat cctggccgct atatcttgcc
     9721 ggattacaaa ttaactcgtc gccgggccgc attcaaaatt gttaaacata cctttttaac
     9781 gccccactac aagtcttacg ttgccatgga ctctgacaac ggccacacac tctggtttca
     9841 taatttcggt tccctaaccg aagctttatt ctggttagaa accggcctta aaatcagcga
     9901 taccgactcc cattctaact acaaggaatg gatggctaag cacactacgg aaatcgaaac
     9961 cttcaaagac ttgctgcgcg agcagaagca taaacaaggg cccaagacta agaaaaaagc
    10021 caagtagccc gttttgacac ctagattcag ataagcagca gtacgctcat tagcgtgctg
    10081 ctgcttttat ttacgatcaa ctgtgccatt cattactgac taggccaacc taaaagtggc
    10141 tatccaaaaa cgactgcagc ttgcgtgcaa tcacgcgatg accggcattg ttcggatgca
    10201 aagtatccac cgaataaatg gccgcttgag cgggaatcgc aaacgtcatt cccgcatcac
    10261 ggtacaagct caaatgtggg acgccatagt ctgcagtcat ctgggcaatc gctgcttcat
    10321 aatctgactg acgatacccg agaccattag tcaccgcact aaaactgccc ccaaaatcag
    10381 agccaatatg aattgctgaa ataaataatt tcggcacggt cggccaattc gtctgtaatc
    10441 ccgtcagtaa catcattaac gcgccataaa atgtcgtcat atcgcaatca ccgtattgcc
    10501 ctaacggctg atcccgacca tagtcattga cgcccccaaa gacagcaata aaatcagcat
    10561 cttcaggaat agcttgatag cgcaccgcca tcgcatcgta gcgactccca atcgttgaac
    10621 cagagattcc caaattatcg ctccgctcga catcccaatc agccgccaaa atatcatgat
    10681 aatgcaccgt cgccaaccca ttattcgccg taatcgaatc tcccaaccac gccggccgct
    10741 taaaactaac atgcccatta ctaatcgcca tagccaatcc tccctttact atcatcgcta
    10801 tcattctaat ccatcccacc tgaattatgg tagaaagatg ccttttaggg ttggttttct
    10861 gttcgtcagc cggtgagcgt cctattccga cctccggggc tgggtgacaa ttgctggaac
    10921 gcagccgaca tcgatttgag ctaacgcata acccgcgtca tctcaaatac gagtcttatt
    10981 ctaagccgga aggaaatcac ttccgactaa gaataatttg gctactgagc attgtcaccc
    11041 agcccctcca gtctcaagcc acgggttgaa gccgagcatt gtctagccaa cggattaatg
    11101 cggtttggac atttgtccgt tagcatagca agcacagact ttagtggcac cgaacacgtt
    11161 tcggtaagcc gcccgaatgg ctgatgaacg gccacttaac ttggtgcaat tggtcgttgg
    11221 ctattttgat accggaactt taaacgagac gttagggtta ccctaaccac tttgttgagg
    11281 tgttctatta ttactatagt aattccgaaa tagcgagcta tcccaatatc ttttcgacct
    11341 aacagttgat taataaaatt actgtttatg gagaacaatg acaaattcat caaaagttgg
    11401 gtatatcttc gtccaccatt cgaatactgt cccgaatgga aggcgtttcg gccaatgctc
    11461 agcggtgaaa ttccacttag caagcgtcct tggattggtt agtagaagac cagtatttaa
    11521 gacgtggtct tcggcttaaa tctgtgtcca ccgcgttcca gcaattggca gaaatgcctg
    11581 gagagcggcg taggacgaac gaactaagca ggtttacgct aaccggaact gtttccagcg
    11641 ggcctaagct ggtggctgtt gactttaaat aaaggcatct ttctaccatt atttcaaaca
    11701 ggtgggccaa tcttaaaagg ctcgtattat ggaaatccat aatacgagcc tagtttaatt
    11761 gatatattta gttcaactga gtagcgctaa tcggcttccg tttcacgttt ccgtgcagta
    11821 cgccgttcgc gtgcgtagtc agttttagtt gtgatttcaa cgtcacgtgc tagccgtttc
    11881 cggcgtgcta attcagctgc tttggcattg gctttcgcag cttccttgac tggatcagtc
    11941 gttaagtcgt gatggatcga gtacagtaag acgagcgcga caatcgttaa tgggaagcca
    12001 gacatcgcac agatggactg aatcgattca aagccaccga ccgtgacaag ccccaatgag
    12061 aagactagga agataacgac ccagctcatc cgattgaaac gacttggttg ttcccccgcg
    12121 gccaactttt tactagtaaa tgacgaggta atgaaggcaa atgaagatac cgtcgttgct
    12181 aagaaaataa agcaagatag gcagtacaaa gccagcataa tcatcttcaa tggtaaggtc
    12241 gacaatactg ctgcaatcac agcggcttgt ccttgcgtat ttaagatatg aactaagtta
    12301 acgatgccca tccgttgcaa gtataaggca taaccaccca agatggcgta gaaactgaca
    12361 caacctaatg agccccatag caacatacca ccgagtacct gacgaatcgt ccggccccga
    12421 gaaatccggg caatgaataa gcccatgact ggcataaagg ataaccacca gccccagtag
    12481 aagatcgtct gccgttgcat ggccgttgcg tgaccatttg gtgcagtatt cgtgctcaac
    12541 gtaataaact tattgacaaa caagccaata ctattagttt ctgagtttaa aatatacaaa
    12601 gttgggccaa caattaaaac aacgattagg aagccaatcg ctaaccaaac atgggcagca
    12661 cttagccgac cgattccctt cttcaagcca ttaaaaacag ccatggcgaa aattacgaat
    12721 aataaggcaa ataaccctaa ctttaaagtc atcgtatcgg caatcccggt aacggcactc
    12781 aaaacttttg aaatgacggg gatttccatc ccgactgaag taccaacacc acccataatc
    12841 ccaataataa cgagaaaatc aatcgtattc cgggcaattt gcttaccctt accaggacct
    12901 tgtagtactg aaattgcggc actgagccgc tgaaccttga tgtgtttaac atacattgca
    12961 taggcaattg caatcgtggc tggcgcaaac atcatccacg ccattggtcc ccaattaaat
    13021 tgtcccagca tgtgcgcata attatatgca gaagttgaaa acggcttgac gccgaatgaa
    13081 gggctttgga ggtaccgtaa cgggtcaacc atgctcaaca ttaaaatgct ggcatcgatc
    13141 ccggttgcgt aaaccatact gccccagtga tacgttgaaa attctggttt gtcatcagga
    13201 tcaccaagtt tggttttccc taacttacta aaccctaagt aaatgaaaaa gataaaagtg
    13261 atcacatata ccgacatata aagccagctc atgttatttg tgagccagtt caagatgcca
    13321 cttaaactcg tctccagcga atggcccccc attaataaaa caacggaagc cgccgcaaag
    13381 agcccaattg ttggtaaata gacccaccaa tcaatattct tactttttaa aataataaac
    13441 ctgctactga gcatatactc tctatattta gatcaaattc gtggttcttc ctaccagcaa
    13501 tggtagtccc cacgcgtaaa tttccgacta gcaatcggta cacccctccg agttaatcct
    13561 cggagcactc agcaccctga ctgtatcagg tttgaccggc attgtcatcc gcattctgtt
    13621 tgtgctaact caaaatcagt agcagaattt ccttctttcc gttggttgaa tccggacaac
    13681 gccatactga caaatgattt ttaattgctt aatcgacgtt ggtgttcatc ttgtttagct
    13741 agtgtttcta ttaccatcgt gcctttagca cacgaccgtc gtcacaccac gtaacgatta
    13801 atggttacac tgctcttgct aatagataac ccccttgaat caccagataa gcccaccgca
    13861 caactgttag attaattgct tggtgcacca aaaaagcgct tagtaccggg taacaagtta
    13921 ccacctgcac agcgcacgtt ggcttataca aatgctgatt tcagtatttt ctgatatctg
    13981 atgttcgttt ataagtatac tagtattaaa tcagaagtaa aatcaaccat tttgagccgt
    14041 cgaggcctaa cccgtcaagg attagacgag ttttacaccc atattttttt tgaaactttt
    14101 taaaagtttt cgtaataatt agtttttagt ttagaatcat tcttatctgt ttcaattaaa
    14161 ccgatttcat gttattcttg taacaagtaa aaaaacgtta tcatctaaaa ggaggggaac
    14221 tgcatgcggc actactataa attaatttta acggtcagcg tcggtatcat tgcggttatt
    14281 ttacagtttg gtttgcacta ccaattggca gcacaaatca tcattacatt aatggggtca
    14341 cttatggcct tatcaatgtt agttgagatg atcaaaacct tacgttcagg taagtacggg
    14401 gttgatttat tagcaattac ggcgattgtg gcaacactag ctgtcggcga atattgggct
    14461 agccttgtcg ttctaattat gctcactggg ggtgactcgt tagaagatta tgcggccaaa
    14521 cgagcgaata ccgaattgaa agccttgctc gataattcac cacgtattgc ccaccgctca
    14581 gtcgccggcc aattaacaga tattgccgtt gaagatgtcc aaattggtga tcagctagtc
    14641 gtcaaacctg gtgagctagt tccagtagac ggtcacctta ttcaaggaac ggcactcttt
    14701 gatgaatctt cattgacggg tgaatctaaa ccagtcgaca agcacgttgg cgatgacatt
    14761 atgtctggtg cggtcaacgg cgatagtgcc gttacaatgg ttgttgataa attagccatt
    14821 gatagtcaat accaacagtt agtcaaattg gttaaagaat ccgaatcacg accagccaaa
    14881 ttcgtacggc tggccgatcg ctatgcagtc ccattcacct tggtagcata cgtcattgcc
    14941 ggagtagctt gggcattcag cggtgatccc caccgatttg cagaagtcct cgtagtggct
    15001 tcaccttgcc cgctgattct cgccgcaccc gttgcactcg tctcagggat gagccgaact
    15061 agtcgaaacg gaatcgtggt caagactggg gacatgttgg agaagttatc tacggctaag
    15121 tccgccgcgt ttgataagac ggggaccatt accagtggtc aattaacagt caaccaaatt
    15181 gttcctcagc ctggttttac tgccgaacaa atcttgcacc tcgcagcgag cgctgaacaa
    15241 aactcaagtc atatcctggc ccgctcactc gtcaagtatg cgagtgccac tagcctcagc
    15301 ccggcaacac aattagcaga agtaacgggt aatggggtca cggcaacgat tgagcagcaa
    15361 caggtcaaag tgggcaaact taaattcgtc gcaccgacta caaccgccaa gccacttgct
    15421 accactgcta tctacgtcgg cattgatgac cagtacgcgg gttacatcac gtttatcgac
    15481 aatgtccgcc ccgaagcagc cgccacgctt caagcactcc acgctgaggg cgttcaaaac
    15541 gtcatgatgc ttactggtga ccaacaggca attgctgatc atattgccgc cgatgtcggt
    15601 atcgataccg ttgctgccga cctcctaccc gcagataaga ttgcccactt aaaggctgta
    15661 ccagcggccg aacgccccgt tatcatggtt ggtgatggtg ttaatgacgc gccttccttg
    15721 gctgttgctg acgtcggcat tgccatgggc gcccatggct caactgctgc tagtgaatcg
    15781 gccgacgtcg tcatcttaaa agacgatctc agtcgcgtgg tcacggcggt gcgcattgct
    15841 aaagatacca tgcaagtggc taaacaagcc gtttg
//
