LOCUS       c00148_gnlPro..         4881 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBNOJKCK_148.
ACCESSION   c00148_gnlPro..
VERSION     c00148_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 06:50:01
            Original ID  :: gnl|Prokka|DBNOJKCK_148
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4881
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4881
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[201:4432]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      202..4432
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4881
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4881
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..205)
                     /locus_tag="ctg148_1"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVE"
     CDS             complement(202..762)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg148_2"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-20, bitscore: 60.8,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLMNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(795..1355)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg148_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.6e-49, bitscore:
                     155.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSESTHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGF
                     GLPAAIGATFGRPDRTVCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQW
                     QAMFFNRRYSFTPMMNPDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACV
                     EEEGNVMPMTPPGGSVNQMLLEC"
     CDS             complement(1352..2545)
                     /locus_tag="ctg148_4"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSLGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRQAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTDHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRA"
     CDS             complement(2630..4432)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg148_5"
                     /sec_met_domain="ILVD_EDD (E-value: 1.7e-219, bitscore:
                     718.0, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKKLFEDAARLIVENAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSPDVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVISGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
ORIGIN
        1 gttcgacagc caagcgggat aatacccaag tataattgtc ctcgtttaga gtcgcgatgc
       61 caaaacctcg gtcgctggca tggaaacccg cacaattcaa caaatggttg cccaatactc
      121 ccattgtcag ccgtccggta aagtcgacat gaaacggttc ggcaacaaac ttgtaggtac
      181 ctattttatt gttctcgctc atcatgattc ctggtgttta ctttgacgat attttgcttc
      241 acggtccgcc agatattcat tgacacgctc aaagcagctg gtcgtaatgg ctacgcgacc
      301 cgaacggacg aactgaagta cgcaatccaa ctggcgcaac tcctcataaa gattggttat
      361 ttcctcactc atgccattct tctcaacaat ggcaaataca gcattcacct ccacaatacg
      421 ggcattgtac ttacggatta ctttggacac ctccggtttt tcttccagcg taggggtcgt
      481 tattttataa agggcaatct cgtgctgata gatttcatca tccgtgaaat aatgggcttg
      541 cagcacatct attttcttgg taatctgctt ggtcaccttt tcaatggtat ccttatccgt
      601 ccaagcggta atggtatatt tatgtacccc cttgatggag gaggccgata cattcaaact
      661 ctcgatgttt atctgccggc gggtaaacac agccgtcacc tgattcatca aaccggcaaa
      721 gttttccgaa tgaacaatga ttgtatatag ttttttatcc atagatagag taaattcttt
      781 aatttcgcat gacttcagca ttccaacaac atctgattga ccgaaccgcc cggaggtgtc
      841 atcggcatta catttccttc ttcctccaca caagcttcga gcaggaacgg tccgtcagtc
      901 gctatcatct cgtcaatcgc ttttgccagc tcctcgcggg tcattaccct gcgtgcagga
      961 atatcatatg ccgaagcaat cttcatataa tccggattca tcatcggagt aaacgaataa
     1021 cgacgattga agaacatcgc ctgccattga cgaacattgc ccaggaagtt attgttcaac
     1081 agaatcatct tcaccggagc cttttgttcc atgatggtac ccagttcctg caggttcatc
     1141 tgcaagccgc cgtctcccat gaatacgcat accgtgcggt ccggacgtcc aaaagtggca
     1201 ccgatagctg ccggaaggcc gaagcccata gtacccaggc caccggaagt aacaatgcta
     1261 cgttccttac tgtatttgaa ataacgggcg gacatcatct gattctggcc gacatcagtc
     1321 accaatatcg cctcgttatg ggtagactca ctcacgcacg caccacttca cccatgctta
     1381 gcgcttttcc tgccggatgt aattccggac ggattacctt ttcctcttcc acttcctcgt
     1441 attgccggaa actgtcaatc cattcctgat ggttggcggg ttccagcaat tgggtaacgg
     1501 cagccagtgt ctctttgcaa tctcccaaga cagcaacatc ggtctttaca ttcttatcta
     1561 tttcggcagg gtcaatatca aagtggataa tcttcgcctg cttggcatat gtttccaatt
     1621 tacccgtcac acggtcatca aagcgcatgc ctacggcgat aaggacatca catttattgg
     1681 tattgatatt gggccccagg ttaccgtgca taccaagcat tcctttgttc aacggatggt
     1741 ccgtaggcaa ggcagaaagt cccaataaag tgcatccggc aggcattccg gctttctcaa
     1801 tgaaagcacg aagctcttgc tgggcttctc ccagctccac gccttgtcct accagcacca
     1861 aaggccgttc cgcaccattt attaattcag cagcctgccg tatggcctcc ggctccattt
     1921 cgggaacggg aagatagcta cggacatagt ccaccttagt aggcgcatat tctgttttct
     1981 ccacttgggc gtttttagca aaatccagca cgaccggtcc cggacgtccg ctctttgcca
     2041 catagaaagc acgtgccact gcccaggcca catcttctgc acgacgaatc tggtaactcc
     2101 atttcgtgat aggctgagta atgcctacca agtccacttc ctgaaatgca tccgtaccca
     2161 agaagttcgt ccctacctgg ccggcaatga caacgatagg cgtactgtca atcatggcat
     2221 ctgcaatgcc cgtgatagta ttggtagcac ccggtccact ggtaaccaga caaacgccaa
     2281 cctcgcctga tacacgtgca aagccttgtg ccgcatgggt tgctccttgt tcatggcgaa
     2341 ccaagatgtg gttcaattcc ttccggtggt cgtataaggc atcgaatacc ggcatgatgc
     2401 tccctcccgg atagccgaaa atggtcttta ccccctgatg ctccagagaa cgcatcaatg
     2461 cttctgcgcc tgttattaga gcctcacccc gcccctctcc tagggagagg gaggaaaagt
     2521 tactcttttt attattatca gccatacttt atctttttat taaaaacttc ggaaatttgt
     2581 atcattccct cctcccctct ctttcggaga ggggtcgggg gtgaggcctt taatcaatca
     2641 gcctcacagc ccctttgtca gcggaactca ccatactggc atatgctttc aatgctttgg
     2701 agacttcacg gttacgggtt accggagtca tagggcgtgc tgcaagctct tcatccgtca
     2761 acttcacatt gatagaacgg ttcggtatat caatttcgat aatgtcccca tccttaatct
     2821 taccgatatt accaccggca gccgcttcgg gagaaacatg tccgatactt agtccggaag
     2881 taccaccact gaaacgcccg tcggtaatca atgcacactc cttacccaga tggcgggatt
     2941 tgatataaga agtaggataa agcatctctt gcatacccgg tccacctttc ggcccttcgt
     3001 gagtgatgac gacgacgtct ccactgatca cctttccacc cagaataccg tcgcaagccg
     3061 catcttgtga gtcgaagact ttcgccggcc ccgtaaattt ccagatactc tcgtctacac
     3121 cggcagtctt gacaacgcaa ccgtcctgag ctatatttcc cttcaaaacc gccagaccgc
     3181 catccttgct gtatgcatgt tccaaatcac ggatacaacc ggtcgcacgg tccgtatcga
     3241 gttccttata agacgcattt tgtgaaccaa gtaccagatt gaactttccg gctgccgcac
     3301 tggagtattt cttgattgcc tctttacata catcagggct ggtaatacta taccggtcga
     3361 ttgcctctgc caacgtcatt ccatccacac ggcggacatt tgtatcgacc aatccgccct
     3421 tggctagctc atccatgatg gcaatgatgc caccggcacg gttaacgtct tgtacatgat
     3481 acttttgggt attgggagcc accttgcata agcagggggt cttgcgggag agcatgtcaa
     3541 tgtcgtccat cttaaaatcc gctccggctt cgtgagccac agccaacaaa tgaagtaccg
     3601 tattagtgga accgcccatc gcaatatcca gcgtcatggc attcaaaaat gcctcgcggg
     3661 tagcaatact gcgcgggagt acactctcat ccccttcttc ataatatcta aaggcattct
     3721 ctacaatcaa cctggctgca tcctcaaata gtttcttgcg attttcgtga gtggctacaa
     3781 tcgtgccgtt accgggcagt gccaatccaa tcgcttcatt caagcaattc atggaattag
     3841 cggtaaacat gcctgagcag catccgcaag tggggcaggc atgttgctca atctgtgcca
     3901 cctctttatc gcccacactt tcatcagcag atttaatcat ggcatcaatc aaatccaaat
     3961 gctgtccgtt ccattccccg gcttccatcg gaccgcctga aacaaacaca gtcggtatat
     4021 tcagcctcat agccgccatc agcatccccg gagtaatctt gtcacagtta ctgatgcaaa
     4081 ccatagcatc tgccttatgg gcatttacca tatactccac actatcggca atgatatctc
     4141 ttgaaggcag ggaataaagc ataccgtcgt gtcccatagc gataccgtcg tcaatggcaa
     4201 tcgtattgaa ctccgcagca aaacacccca gtttttcaat ctcttccttt acaaactggc
     4261 ctatttcgtg cagatgtaca tgtccgggaa cgaattgtgt aaatgaattg actatagcga
     4321 taatgggctt acccatctgt tccttcttca taccattcgc cgtccacaat gcacgggctc
     4381 ccgccatgcg gcgaccttgt gtgctgaacg agctgcgtaa ctgatgcttc attttcaaat
     4441 ctccttttaa tgaaaaagcc tctcccacta tagtgagaaa ggcttaataa attatcttct
     4501 aacgtacgaa tacatacata acctttctca cgctcttgat gccaccacca cgacgcgaat
     4561 aatatgcagg actgccaggt taatagatgt atgtaaattc ataacttaat tcttcttttt
     4621 tgtttcaaac gtgctgcaaa ggtaagggct tttttataat ctccaaacaa attgaagaaa
     4681 aaaataagat aaatatgaat aatcgtaaga aaatatcgcc ctaaaatcct attttatcac
     4741 ttaacagttc taaatagaac cattcagaca gccaatataa atgtattgcc aatcattgaa
     4801 accatttaat aatctgaaaa ttaccaaagg ctctctacat cccgaaacaa ataattcgta
     4861 tctttgtctc ttcaaatact c
//
