LOCUS       c00117_gnlPro..         8313 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NDGFIKAM_117.
ACCESSION   c00117_gnlPro..
VERSION     c00117_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:40:34
            Original ID  :: gnl|Prokka|NDGFIKAM_117
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8313
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8313
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2542:8312]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2543..8312
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8313
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8313
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             69..1355
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_1"
                     /sec_met_domain="SDH_alpha (E-value: 5.1e-63, bitscore:
                     202.0, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTESERRQIIELIKKEVIPAIGCTEPIAVALCVAKAAETLGAKPE
                     KIEVLLSANILKNAMGVGIPGTGMVGLPIAVALGALIGKSDYQLEVLRDCTPEAVEQGK
                     LFIAEKRICISLKEEITEKLYIEVICKTGDKTAKAIIAGGHTTFIYIARDEQTLLDKQH
                     TVSEEEEEASPELNLRKVYDFALTAPLDEIRFILDTARLNKAAAEQAFKGNYGHSLGKM
                     LRGTYEHKVMGDSVFSHILSYTSAACDARMAGAMIPVMSNSGSGNQGISATLPVVVFAE
                     ENGKNEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGNYNQVA
                     FAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAMMAMEDRCVTSVEGIIDADVDQ
                     SIRNLTRIGSQAMNETDKMVLDIMTHKGC"
     CDS             complement(1483..2061)
                     /locus_tag="ctg117_2"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYTMEDGEKELFEEAKAEHPFQFISGLGTTL
                     EDFENQITALSKGDKFDFTIPADKAYGQYDEQHVIDLPKNIFEIDGKFDSERIKEGNIV
                     PLMTGDGQRVNASVVEIKPDIVVVDLNHPLAGADLIFEGEILESRPATNEEIQELVKMM
                     SGGDGCGCGCDSCGDGCGDDCGCEGGHCH"
     CDS             2543..4342
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_3"
                     /sec_met_domain="ILVD_EDD (E-value: 1.6e-217, bitscore:
                     712.0, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTQLFKDAAELIVKNAKLYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAIAHEAEVDFKMDDIDMLSRKAPCLCKVAPNTQKYHIQDVNRAGGIIAIMDELAKGG
                     LIDTSVRRVDGMSLAEAINEYSITSPNVSEKAIKKYSSAAGNRFNLVLGSQGMYYKELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPARKINVRLTDEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRLI"
     CDS             4402..6066
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.1e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMRSLEHQGVTTIFGYPGGSIMPVFDALYDHQNILNHILVRHEQG
                     AAHAAQGYARVSGDVGVCLVTSGPGATNTVTGIADAMIDSTPIVVIAGQVGTGFLGTDA
                     FQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIARSGRPGPVVLDFAKNAQVEKTK
                     YEPTKVDFIRSYVPVPDTDEETVQAAAELINNAERPLVLVGQGVELGNAQSELREFIEK
                     ADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNINTNKCDVLIAVGMRFDDRVTGNL
                     ATYAKQAKVIHFDIDPAEVNKNVKVDVAVLGDCKETLASVTKLLKKKTHTEWIDSFKEY
                     EKVEEEKVIRPELHPATNSLSMGEVVRAVSNATRHEAVLVTDVGQNQMISARYFKYTKE
                     RSIITSGGLGTMGFGLPAAIGATFGAPERTVCVFMGDGGLQMNIQELGTIMEQKAPVKI
                     ICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRAFTREELKEAIAE
                     MLATDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             6123..6686
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_5"
                     /sec_met_domain="ALS_ss_C (E-value: 3.5e-19, bitscore:
                     57.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITALTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKLIRRYNARVVEVNPVFSIVEKNGMSEDITSLYGELKALNCVLQFVRSGRVAITTS
                     CFERVNEFLDGREAMYNQSKNQQE"
     CDS             6686..7405
                     /locus_tag="ctg117_6"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYENFSVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVTSDQPIATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYKTKRIRRFEMAYVAESYFGDELSFFCDEV
                     NANEFHVEVKKNGNEVV"
     CDS             7497..8312
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_7"
                     /sec_met_domain="IlvN (E-value: 2.5e-47, bitscore: 149.4,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 6.9e-27, bitscore: 83.4,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTTETVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQREGKTYDKAVADGWVPGETLFGIEEACEKGTIVMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTA"
ORIGIN
        1 tttgttcatt atagaatgtt ggaaaagaaa gaatttccta tttttgtgga accaaaattt
       61 ataagtccat gactgaatca gaaagaaggc aaattataga attgattaag aaagaggtca
      121 ttccggctat tggatgtacg gaacctatcg cagtggcgct ttgtgtagct aaagctgccg
      181 aaacactggg agcgaaaccg gaaaagatag aagtcctgtt aagtgctaat atattaaaga
      241 atgccatggg agtcggaata ccgggaactg gtatggtcgg acttcccata gctgttgctt
      301 tgggtgcgtt gattggcaaa tcagactatc agttggaggt gttgagggac tgtacgccgg
      361 aagcagtgga acaaggaaaa ctgttcatcg cagaaaaacg gatttgtatt tctctaaagg
      421 aagagattac ggaaaaactt tatatcgaag taatctgtaa aacgggagat aaaacagcta
      481 aagccatcat tgccggtggg catactacct ttatatatat agccagggat gaacaaacgt
      541 tgctcgacaa gcaacatacg gtcagcgagg aagaggaaga ggcttcgccc gaattaaact
      601 tgcgtaaagt ctatgacttt gcactgactg ctccgctgga tgagatccgc ttcatccttg
      661 atacagcccg cttgaacaaa gctgctgccg agcaagcctt taaaggtaac tacggacatt
      721 ctttaggtaa aatgcttcgg ggaacttatg agcataaagt gatgggggat agcgtgtttt
      781 ctcatatcct ctcttatacg tcagctgctt gtgacgcccg aatggccggt gctatgattc
      841 ctgtcatgag taattccggc agcggtaacc aaggaatatc cgctacactc cctgttgttg
      901 tttttgccga agaaaacgga aagaacgaag aggaactgat ccgtgcttta atgttaagcc
      961 atctcactgt tatatatatt aaacaaagtt tgggacgttt gtctgctttg tgtggctgtg
     1021 tggtagctgc cacaggttcc agttgtggaa tcacctggtt gatgggagga aactacaatc
     1081 aggttgcctt cgccgttcaa aacatgattg ctaatctgac aggaatgatt tgtgacggtg
     1141 caaaaccgag ttgtgctttg aaagtaacca ccggagtttc gacagccgta ttatctgcca
     1201 tgatggcaat ggaagaccgt tgtgtgactt ccgtggaggg aattatcgac gcagatgtag
     1261 atcaaagtat ccgtaacttg acaagaatcg gctcgcaagc catgaacgaa acggataaaa
     1321 tggtgcttga catcatgaca cacaaaggat gctgatttta agtattaggt atcaagtatt
     1381 aagtattagc cggaatgacg gcataaaaaa agtattaagt attaaaactc cagctatatc
     1441 agcacgaaat taatacttaa tactttatac ttaatgcttc aattaatgac agtgtccgcc
     1501 ttcgcaaccg cagtcgtcgc cacagccatc accgcagctg tcgcatccgc aaccgcagcc
     1561 atcaccacca ctcatcattt tcacaagttc ctgaatttct tcgttcgtag caggacggct
     1621 ttccagtatt tcaccttcaa agatcaggtc agcaccagcc aacggatggt tgaggtcaac
     1681 tactacaata tccggtttga tttctactac gctggcattt acgcgttgac cgtcaccagt
     1741 catcaaaggt acgatgttac cttctttaat acgttcgctg tcaaatttgc catctatttc
     1801 aaatatattt ttggggaggt caatgacgtg ttgttcgtca tattgtccat aagccttatc
     1861 tgccggaatg gtaaagtcaa atttatcacc tttagaaaga gcagttattt gattttcgaa
     1921 gtcttcgagt gttgttccta atcctgaaat gaattgaaag ggatgttctg cttttgcttc
     1981 ttcgaacaac tctttttcac catcttccat tgtatatagt ttgtatgcaa cggtaatgta
     2041 cttgttttct actgtttcca tctgatattt tttgtttctg attaataatt cccggtaatc
     2101 cggggcgaca aagatacgaa ttatttgctt gtcctccggt atagggaggg taaatttcag
     2161 attattaagt gcttttgtca gaaaaagaag gtggagtgtg cacttagata atagttgtaa
     2221 attcaacctt taagtgataa aatagagaaa taacacctct cttttcttac aattattcgc
     2281 ttttaagtga tttttttctt cgatttgttt ggatataata aaaaagccct tacctttgca
     2341 gcacgaaaat aaagaaaaga agatatgaat atgttacata catctattaa cctagcaatc
     2401 ctgcatatta ttcgcgtcgt ggtggtccca tcaagagcgt gagaaaggtt tttgtgttgt
     2461 atgtgttcgt accataaaag atagaattta gagcctttct cacttgtgtg aggaaggctc
     2521 tttaattaaa agatagattg aaatgaaaaa gcaattacgc agttcgttta gtacacaagg
     2581 ccgtcggatg gcgggagccc gtgcgttatg ggcagccaac ggcatgaaga agaatcagat
     2641 gggtaaaccc attatcgcta tcgtcaattc gttcacccag tttgttccgg gacatgtgca
     2701 tctgcatgaa atcggtcagc tggtgaaggc agagattgag aagctgggat gcttcgctgc
     2761 ggaattcaat acaatagcta tcgacgacgg tatagcaatg ggacatgatg gtatgcttta
     2821 ctcgcttcct tcacgtgaca tcattgcaga cagtgtagaa tatatggtta atgcgcacaa
     2881 ggcagatgca atggtatgta tcagcaattg cgataagatt actcccggaa tgttgatggc
     2941 ggctatgcgt ttgaatattc ctgccgtatt tgtatcgggc ggtccgatgg aagccggaga
     3001 atggaatggt cagcacctgg atttgatcga cgcgatgatt aaatcggctg atgaaagtgt
     3061 cagcgatcag gaagtagcga atatcgagca aaatgcttgt cctacttgcg gatgttgttc
     3121 cggtatgttt accgccaatt caatgaactg cctgaatgaa gcaatcggac tggctcttcc
     3181 cggaaacgga accatcgtag ctacacacga gaatcgtacg cagcttttca aagatgcagc
     3241 agaactgatc gtaaaaaatg caaagttata ttatgaagaa ggagacgaaa gtgtgcttcc
     3301 tcgtagcatt gctacccgtc aggctttctt gaatgccatg acgctggata tagcaatggg
     3361 tggttctact aatacagttc ttcacctgtt ggctattgct catgaagcag aggtagattt
     3421 caagatggat gatatcgata tgctttcccg caaggctcct tgtctctgca aggtggctcc
     3481 caatacacag aaatatcata ttcaggatgt aaaccgtgcc ggtggtatta ttgctatcat
     3541 ggatgaactg gcaaaaggcg gtctgataga tacatctgtt cgacgggtag acggaatgtc
     3601 attggcggaa gctattaatg aatattcaat caccagcccg aatgtaagcg aaaaggcaat
     3661 taaaaaatat tcgagtgcag ccggaaatag attcaatctc gtacttggtt cacagggcat
     3721 gtactataag gaactggata aagaccgtgc aaacggatgt atccgtgatt tggaacatgc
     3781 ttatagcaaa gacggtggat tggccgtatt gaaaggcaac attgcccaag acggttgtgt
     3841 ggtaaaaaca gcaggtgtag acgaaagtat ctggaagttt accggacctg ccaaagtatt
     3901 tgattcgcaa gaagcagcct gtgaaggcat cctcggaggc cgagtcgtca gtggcgatgt
     3961 agtcgtcatt acgcacgaag gtccgaaggg tggtcccggt atgcaggaaa tgctttatcc
     4021 tacctcttat atcaaatctc gtcatctcgg aaaagaatgt gctttgatta ccgacggacg
     4081 tttcagcggt ggaacttccg gattgagtat cggacatatt tctcctgaag cggcagctgg
     4141 aggcaatatc ggaaaaattg tagacggaga cattatcgaa atcgatattc cggcccggaa
     4201 gattaacgtg cgactgacgg atgaagaact ggcggcccgt ccgatgactc ctgtcactcg
     4261 tgaccgttat gtaccgaaga gcctgaaggc gtatgccagc atggtaagct ctgccgataa
     4321 gggagcagtg agattaatct gatatagttc atttatcaac tatcaactaa tatgaaagat
     4381 ttaataacag gtgcagaggc tatgatgcgc tccttggaac atcagggagt gactaccatc
     4441 tttggttacc ccggtggttc tattatgccg gtattcgatg ccttgtacga tcatcaaaat
     4501 atattgaacc atatcttggt tcgtcacgag cagggagccg cccatgccgc acaaggttat
     4561 gcccgtgtgt cgggtgatgt aggtgtttgc ctggtgacga gcggtcccgg agcaaccaat
     4621 acggtaacag gcattgcgga tgcgatgatc gatagtacgc ctatcgtggt gattgccgga
     4681 caggtaggaa caggctttct tgggaccgat gcttttcagg aagttgactt ggtaggtatt
     4741 acccagccaa tcactaaatg gagttatcag attcgccgtg cggaagatgt agcctgggcg
     4801 gtagcacgtg cgttttacat tgcccgtagt ggtcgtccgg ggccggtggt actggacttt
     4861 gccaaaaatg cgcaagtgga gaaaacgaaa tacgaaccaa cgaaagtcga ttttatccgt
     4921 agttatgttc ctgttcccga tacggacgag gagactgtac aggctgctgc cgaactgatt
     4981 aataacgctg aacgtccgct tgtattggtt ggacaaggtg ttgaactggg aaatgcacag
     5041 agcgaattgc gcgagtttat cgaaaaagcg gatatgcctg cgggttgtac gctgctcgga
     5101 ctttcggctt tgccgacaga acatccgttg aataaaggta tgttgggtat gcatggcaat
     5161 ctgggaccga atatcaatac caataaatgc gatgtgctga ttgctgtcgg tatgcgtttt
     5221 gacgaccgtg tgaccggtaa tttggctact tacgccaaac aggcgaaagt gattcatttt
     5281 gatatcgatc ctgcagaagt caataagaat gtaaaggtag atgtagctgt tttgggagat
     5341 tgcaaggaga cattggcttc tgtgactaaa ctcctgaaaa agaaaactca taccgaatgg
     5401 attgatagct tcaaagaata tgagaaagta gaggaagaaa aagtaatccg ccctgaactt
     5461 caccctgcaa caaactcttt gagtatggga gaagtggtac gtgcggtaag caatgccact
     5521 cgacatgaag cagttttggt aacagatgta ggtcaaaatc agatgatatc tgcacgttac
     5581 ttcaaatata cgaaagaacg cagtatcatc acttccggag gacttggaac aatgggcttc
     5641 gggcttcccg cagctatcgg ggcaactttt ggagcaccgg aacgtactgt atgcgtattt
     5701 atgggagatg gcggactgca aatgaatatt caggagttgg gtacgattat ggagcagaaa
     5761 gctccggtga aaattatctg cctgaataat aattacctcg gaaatgtacg ccagtggcaa
     5821 gctatgttct tcaatcgccg ctattcgttt actccgatgt tgaatccgga ttacatgaag
     5881 attgcttcgg cttatgatat tccttccaaa cgtgctttca cccgtgaaga actgaaagaa
     5941 gctattgcag aaatgctggc gacagatggt ccgttcctgc tcgaagcgtg cgtagtggaa
     6001 gaaggcaatg ttttgccgat gactcctccg ggtggttcgg tcaatcagat gctgttggaa
     6061 tgctagggga agttgaatat tgagaatgga agattgaaag ttcgcaatta aaatttagga
     6121 ttatgagtga caagacatta tatacgataa tagttcattc cgaaaatata gccggattgc
     6181 tgaatcaggt aactgctgta tttactcgtc ggcaaatcaa catcgagagt ctgaatgtat
     6241 ctgcttcttc tattaaaggt gtacacaagt atacgattac agccttgacg gataaggaca
     6301 ccattgagaa ggtagtgaaa cagatcgaaa agaagatcga tgtgattcag gcacattatt
     6361 tcaccgagga tgaaatatac ttccatgaga ttgcactata taaggtatct actcctgctt
     6421 ttcaggaaac tccggaagca tccaagttga tccgcagata caatgcccgt gtagtggaag
     6481 ttaatccggt attttctatt gtcgagaaaa atggtatgag cgaagatata acctcactct
     6541 acggtgaact gaaggcttta aattgtgttt tgcagtttgt acggtcggga cgcgtagcga
     6601 ttaccaccag ttgctttgaa cgggtgaacg agtttctcga tggacgggaa gccatgtata
     6661 accagagtaa aaaccaacaa gaataatgag tgaagaaaat aaaataggaa cttatcagtt
     6721 tgtggcagag ccgttccatg ttgactttaa cggacgtctg actatgggcg tactgggaaa
     6781 tcatctattg aattgtgctg gttttcacgc aagtgaccgt ggctttggta ttgcaacact
     6841 gaacgaggat aattacacat gggtgctttc acgtctagcc attgagttgg atgaaatgcc
     6901 ttatcagtat gagaatttct cggttcagac ttgggtggaa aatgtctacc gcttgtttac
     6961 ggaccgtaat tttgctatta ttgataagga tggaaagaag attggctacg cacgttccgt
     7021 atgggcaatg attaatctta atacccgcaa gcctgccgac ttgttgactt tgcatggggg
     7081 aagtatcgta gactatgtct gtgatgagcc ttgcccgatt gaaaagcctt cacgtatcaa
     7141 agtgacaagc gatcagccga tagctaccct gacggcaaag tacagtgata tagatatcaa
     7201 tggtcatgta aacagcatcc gttacatcga acatatcctt gatttgttcc cgattgaatt
     7261 gtataagacc aaacgtatcc gtcgttttga aatggcgtat gtggcggaaa gctattttgg
     7321 tgatgaactc tctttcttct gcgatgaagt gaacgcaaac gagtttcacg tagaagtgaa
     7381 gaagaatggc aacgaagttg tttgacgctc gaaagtgata tttgaataaa tgtgagaata
     7441 taaaatcaat taataacaga tggcgtaagt catcaaaaac taaaaacaaa aagaaaatgg
     7501 cacagttgaa ttttggaggt actactgaaa ctgtagtaat ccgtgacgaa tttccattgg
     7561 aaaaagctcg tgaagtattg aaaaatgaaa caatcgctgt aatcggttat ggcgtacagg
     7621 gtcctggaca ggcactgaac ttgcgtgata acggtttcaa tgtaatcgtt ggtcaacgtg
     7681 aaggaaaaac atacgataag gcagtagcag acggatgggt tccgggtgaa actttgttcg
     7741 gtatcgaaga agcttgtgag aaaggtacta ttgtaatgtg tctgttgtct gacgcagcag
     7801 taatgtcagt atggcctact atcaagcctt acctgactgc cggaaaagct ctttatttct
     7861 cacacggttt tgctatcact tggaacgacc gtacaggtgt agttcctcct gctgatatcg
     7921 acgttatcat ggttgctcct aaaggttcgg gtacatcttt gcgtactatg ttcctcgaag
     7981 gacgcggctt gaactcttct tatgctatct atcaggatgc tacaggcaag gcttacgaaa
     8041 gaaccatcgc actgggtatt ggtatcggtt ccggttatct gttcgaaaca actttccaac
     8101 gtgaggctac ttctgacctg acaggtgaac gtggttcatt gatgggggct atccaaggtt
     8161 tgttgctggc acagtacgaa gtattgcgtg aaaacggtca tagtccttct gaagcattca
     8221 atgaaacagt ggaagaactg acacagtcat tgatgccgtt gtttgcaaag aacggtatgg
     8281 actggatgta cgctaactgt tctactactg ctc
//
