LOCUS       gnlProkkaBMBODDLG_563  13312 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMBODDLG_563.
ACCESSION   gnlProkkaBMBODDLG_563
VERSION     gnlProkkaBMBODDLG_563
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 04:22:19
            Original ID  :: gnl|Prokka|BMBODDLG_563
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13312
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13312
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3076:3864]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3077..3864
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13312
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13312
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..317
                     /locus_tag="ctg562_1"
                     /transl_table=11
                     /translation="MEFVPQEYVAACSPDISWQPKPNATPYSSDSHFWIDKNNNGILDT
                     NEQINSNRYTCDNSGALPNGEKGQYVFEDPSKERLFAYKTKGNSIIVYKLDQIIIGNHS
                     "
     CDS             627..1733
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg562_2"
                     /sec_met_domain="PF04055 (E-value: 2.8e-26, bitscore: 82.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESLQDINPVERALVNKANQNHVPITANFELTPTCTLNCDMCFIH
                     TERNVVERHGGLLPLQQWLDWAEQLQDMGTLFILLTGGEPMLYPHFKELYTRLREMGFI
                     LTLNTNGTLIDNEMVRILQTHKPRRVNVTLYGSSRETYGRLCHNPQGYTLCVEALKRLK
                     KAGIDVKLNVSIVRKNEKDYDEIIRLTRQLDIPAEVNSYMFPLSRPECGSLRNIPAERL
                     DADKAARIEMQYVEYKKGNDMARYMHNLKYTLARVEGTQACSLECRAAKSSCWINWQGI
                     LTPCVMMDRPAVDLKKVPMTTAWRQLLEEAKELVSHTECEGCHLRPVCNVCYAAAHCEK
                     TITGNMDYLCQMAKAKERIIMDYPSVTH"
     CDS             1746..2621
                     /locus_tag="ctg562_3"
                     /transl_table=11
                     /translation="MRLNIGPLTIELSGVTEQEIPVNSRLFLDRKPADKRADRHYTFHF
                     VGRLPLPSNDWQAIFRRNDIVIFRKEERETRLLAIGNLNACYALYQEKDERNADIYFIE
                     GLKRELQTDTLFISCLCLERPLSVQGCYILHCTFLDYRGQAILFSGPSGIGKSTHANLW
                     CRHIPGTQVLNGDRALLCPLPNGDYEITGWPVCGSSGICHNERRPLEAIVFIEQASDNT
                     IRPQTAMKHFKALCSQVTINWWNPKLTGKALDDLQVLTRQTSISTYACNMNPEAAFTLH
                     RYLTKLEIIR"
     CDS             2640..3080
                     /locus_tag="ctg562_4"
                     /transl_table=11
                     /translation="MKTVDTKEYISMLRTLIEEGKQVSMIISGSSMAPFLIHARDHICL
                     KSPSGELRKGDMVFYQRSNGEYVMHRIYNVKNEEYYLIGDAQTVIEGPIQREQIFAIII
                     KVKRKGKWIVPEDFQWKFFAHIWPNIIPLRRTIIKTYRFFKR"
     CDS             3077..3358
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg562_5"
                     /sec_met_domain="PF05402 (E-value: 1.6e-17, bitscore: 53.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.1e-15,
                     bitscore: 45.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRTKEFIKRNIAGEIVLVPSGQTAREFNGMVTLTETGEFIWEHI
                     EEAESFNHLVLLILEEYEVDKDTASQDAAGFIMQLLQAGMIRPTGINW"
     CDS             3595..3864
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg562_6"
                     /sec_met_domain="PF05402 (E-value: 4.6e-18, bitscore: 55.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3e-11,
                     bitscore: 33.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLNSNLILRQVGGEYMIVNPFSETMDMAQVYSLNETAARLWKQL
                     ENKEFTVDEAGALLCNEYEVNKDTARNDANELCRQWLETGLAIE"
     CDS             3874..4956
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg562_7"
                     /sec_met_domain="NTP_transf_5 (E-value: 5.1e-35, bitscore:
                     111.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISAPLQKAFMLLLRQGLWDRQEDCSALFPLDEKEWNEIHSMARK
                     QTVQGIIYDGIRLLPTEAVPPRKVLLGWMVEVDTLERVNRQHRETIKALQQIYVQSPSI
                     PFLLLKGIGTADFYPHPEHRIAGDIDLWFGNKTQTEQANQRMEKLGLPVKRGTNGEASC
                     LINRVLIEHHSRLIELHNPFLQKEIRQWEAGVFTNSQGKLPSEANHLLLSTHILKHLIN
                     EGIGLRQLCDIAMAFNALHSVTNKNELECICRKWHIHRWNRLLYALLIKYLGVPADLLP
                     FSTSLCPDKLMQEIWESGNFGHGDERYGERPTGKWANKRYTLKRIFHKTHLSLGYAFDE
                     TFWWLAGLALLRFKEMIKKK"
     CDS             4953..6641
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 221; E-value: 4.9e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg562_8"
                     /transl_table=11
                     /translation="MKELLKKFLQKLTRENLSNTCQLGWKAFKWVMQVTEGYHWLITFS
                     IFSGIFGVVMSLVNVAMSKWIIDVATGAQEGNIYLVATIVALSFLLGMGIKLVSPWIFG
                     KINMRISIRMQNSLSDALMMCSWKGAGKWHTGDLLTRISSDASEVLGMGMGILPNLLVT
                     GLQLASSFIYLWILDARLAWFILGVTPLVLLSKIYFRKVRELSCAQKKMNSEMGTVMQE
                     NLSKRILVRSLGATNYRKQKLHETQEKLFKLGMEQIKFSTFTQGVMGFTFGGGYLCAFL
                     WGIFQLHNHEITFGTMTAFLQLVGQVQGPFLGLISIPPSLIRGWTSVERLMALFEDVEP
                     DEHPVYIDQPLTLNFRKVSFGYEEGQPVLDRFTAAFHPGSSTAIAGPTGTGKTTIIRLI
                     LALVYPEKGRIDLTTDDGRTLSVTPDLRINFVYVPQGNTLLSGTIRENLWLGSPGADEE
                     ALHKVIRLACAEFVFSLPEGLDTKIGEHGYGLSEGQAQRIAIARALLRPGRIWLFDEAS
                     SALDTETTTHLMDNLLQWGKNNTLIFVTHDSRLMERCDQVIHIKE"
     CDS             6663..7472
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 72.7;
                     E-value: 3.7e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg562_9"
                     /sec_met_domain="Poly_export (E-value: 4.6e-14, bitscore:
                     42.2, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTIKLACLLAIIIFSSCASRKDFVYLQDMDELQEYPMVQKYEA
                     IIHRDDRLSIIVNSKNPELSLPFNMSGSRSYSVEADGSISNNEVGVLSDEKEKGYLVDI
                     NGNIDFPVLGQLHVEGLTRRQLTELIKKRLINEELLKDPMVTVNFLNFKFSVLGEVGHV
                     GTFEVKGDRITLLEALAMAGDLTPRSRLDRIAVIREYGNKRRILFHDIRSKDIFTSPYY
                     YLQQNDIVYVEPTNMKATEQAQRKLSTWSMILSFITTITSLVLLTTK"
     CDS             7485..9896
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 290.3; E-value: 4.4e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg562_10"
                     /transl_table=11
                     /translation="MIRMSEQKDMSGDKTLSGGGFNINPVDIIMYLLSKWYWFVLSVSL
                     FGGYAWYQYAKLPFIYSRSATVMIKDAYSNNIGRGLDRFNTYSYTNVSNEILQFQSHKL
                     MRDVVNRLHANVCYLIMDDLREEELYTQAPVKVSFPEEEDHLDFSLTVRIQNRKQVRLS
                     DFSTDATSITLTANLGDTIQSPIGKIVVSPTLYYTDKWFNTPITIRRQSTDTMASLFRS
                     NLNISQAENDASILYLSLRDYSTARAEDVLNMLITVYNEETIKDKNQIAINTSNFINER
                     LVIIEKELGGVENELQSYKQNNDIIDIGSAASMSMSDKRQYSSTTQELELQARMARYIK
                     GYLVDPSKETELIPSNTGIADINIETQIAAYNANKLKRDKLIEGSSDKNPIVQELNKNL
                     IAMRQNIIRAIDNMIVSIDVKLNEARSRAGEAQWRVTNIPRQQQQMLSIERQQRIKEEL
                     YLYLLNKREENALSQATTETDARVLDPAGGGDAPISPNGRSMIMAGVMKGIALPAIVLL
                     LFLFFDTRIRNRKDIEDVVTVPFLGEIPKDSSKRKIENKKTAHGIAVRAQGRDIVSEAF
                     RIIRTNMDFMRVKSKNMQVVTFSSFGPGAGKTYVSSNLAASFAQTDKKVILIDMDIRKG
                     TLTSHTRLHTEEKGMTSFLAGKATTDEIIKHNEICENLDFIPAGPIAPNPSELLLSEQL
                     EVMIAELRNRYDYIFVDNAPVGVVADAAITNRIADLTIFVVRVGKLDRRMLPELEKIYR
                     SGQLNNMSLVLNGAIVKTSGYGGYGYGYGYGYGYVDGSESSWKRLFKKKS"
     CDS             9913..10632
                     /locus_tag="ctg562_11"
                     /transl_table=11
                     /translation="MFGIFKSKYNLINSGLMKGMTDIHSHVLPGVDDGSPDINTSLSLL
                     RYMESIGLREVWLTPHIMEDYPTLNKKLQQQFDVLKAAYSGPLNLRLSSEYMMDAAFTN
                     KLDGEVLPLGSSHLLVETSYMYPPPGLPDILMKIWNAGYQPVIAHPERYLYMEEKDYLL
                     LKEKGYSFQLNLMSLSGYYGPHPKVVSEKLLKQKMYDFVGTDLHHLERYRPMLDQLRLT
                     RRQLEALEGLIANNARI"
     CDS             10619..11623
                     /locus_tag="ctg562_12"
                     /transl_table=11
                     /translation="MRVFNCLSGSILCGLTLLLIFLPCFTPEWAGNFILISLSAIPICI
                     ADGIIFAILLWRHNRWWMLYLFLLLGSLPVLACQFPFHFLHKEKVLDSNQLKLVCWNTE
                     GFRLNKDTLTKAAHSIRVLQPGIVCLQERPHTNLLAWDTIRAAFPDYPYCIINSREDEV
                     LNLAVFSRWPIGNVQEYYFPNSYNKILQADIQMTGQTFRLFNVHLQTTGMNESYSMKDR
                     FQAMRHHTVQRNRQADLLTKAIAESPYPVIVCGDFNDTPASYAYRKISRLLQDCFLQAG
                     QTWSGSYQCWGGFLRIDYTFCSPAFQVNRYLLISNPWSDHKQQHCVLYLDKCS"
     CDS             11644..12489
                     /locus_tag="ctg562_13"
                     /transl_table=11
                     /translation="MTKENWTIEIKPKKKWLDIDLKGIWRYRDLYYMYVKRDIVTVYKQ
                     TILGPLWFLIQPIFTTVMYMFIFGGLAGISTDGVPQPLFYMAGIMLWNYFSSAFNVSSN
                     VFTANAGVFGKVYFPRLVVPLSGITSNLIKFGIQLLLFIAMYLYFYVKGASLHVNAALL
                     LFPFLIFLTAFHAMSWGLIISALTTKYRDLTQLVTFGLQLFMYATPVIYPLNAAPEKYR
                     DIIALNPLTPIFETFKYSCMGCGSLDWGGLAYSTLFMLSTLFCAVVIFSRVERNFMDTV
                     "
     CDS             12518..13312
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 150.8; E-value:
                     8.4e-46)"
                     /gene_kind="transport"
                     /locus_tag="ctg562_14"
                     /transl_table=11
                     /translation="MNDIAIRFDHVGKLYKLGLVGTGTLSHDLNRWWKTTILRQEDPYL
                     KIGETNDRSKKGASEYVWALKDITFDVHQGDVVGIIGKNGAGKSTLLKLLSRVTSPTTG
                     AIRARGRIASLLEVGTGFHPELTGRENIYMNGSIMGMTRHEISHKLDEIVDFAGVERYV
                     DTPVKRYSSGMTVRLGFAVAAFLEPEILVVDEVLAVGDAEFQKKAIGKMQDVSKGEGRT
                     VLFVSHNMAAVRVLCKQGIVLNNGTVAYTGSIEDCVNYFIGNN"
ORIGIN
        1 gtgaagagtt tgttccacaa gaatatgtgg cagcatgtag tccagatatt agctggcaac
       61 ctaagcctaa tgctacacct tattcaagtg attcacattt ttggatagac aaaaacaata
      121 atggaatttt agacaccaat gaacaaatta actccaatcg atatacatgc gacaacagtg
      181 gtgcattacc caatggtgaa aaaggtcaat atgtttttga agacccaagt aaagaacgct
      241 tattcgctta taagaccaaa ggaaattcta tcattgttta taaactagat caaattatta
      301 taggtaatca ttcatgatag tcttgagctt ttaatgaaaa tattggtttt cccttataac
      361 ctatccagta gtttttttag cgaataggtt atagggaacc tttaactttc acattcacac
      421 gagctgtaat tatctaaatc ttcacccagc atgatcagta atcatacaac ttacacagcc
      481 cattctaatc acttaacaat agactattgt atagcaaccg ggtatggatg gttaacatat
      541 actttatggg gtaaataatg agaataccat catctgtcta tcaagcgaaa caatttgtaa
      601 ataagatata aacaaacatt actcccttgg aatccctgca agacataaat cctgtggaac
      661 gggcattggt gaacaaagcc aatcagaacc atgtcccgat cactgccaac ttcgagctga
      721 ctcccacctg tacgctcaac tgtgacatgt gcttcataca caccgaacgc aacgtggtgg
      781 aacggcatgg aggattatta cctttgcaac aatggctcga ctgggcggaa caacttcagg
      841 acatgggtac actcttcatc ctcctcaccg gaggtgaacc gatgctctac ccacacttca
      901 aggagctgta cacccggctg cgcgaaatgg gattcatcct gactctcaat acgaacggca
      961 cacttatcga caacgaaatg gtacgcatct tgcagaccca caagccgcgg cgggtaaacg
     1021 tcaccttgta tggaagcagt agagaaacct acggacgctt gtgccacaat ccgcaaggat
     1081 acaccctgtg cgtggaagcc ctgaaacggt tgaaaaaggc aggcatcgat gtgaaactga
     1141 acgtaagtat cgtacgaaag aatgaaaagg attacgacga gatcatccgt ctgacccgac
     1201 agctggacat tccggcagaa gttaactcat acatgtttcc cctctcccgc cccgaatgcg
     1261 gaagtctgcg taacattcca gctgaaaggc tggatgccga caaagcggcc cgcatcgaga
     1321 tgcaatatgt ggagtacaaa aaagggaatg acatggcacg atacatgcac aatttaaaat
     1381 atacgcttgc ccgtgtggaa ggaacccaag cctgctcttt ggaatgcaga gccgccaaga
     1441 gttcatgctg gatcaactgg caaggcatcc tcaccccctg tgtgatgatg gaccggccgg
     1501 ccgttgacct gaaaaaggtt ccgatgacaa ccgcatggcg gcaactttta gaggaagcca
     1561 aggaactggt atcccatacc gaatgcgagg gttgccacct tcgtcccgta tgcaatgtat
     1621 gctatgccgc cgcacactgt gaaaagacaa tcaccggaaa catggactat ctttgccaga
     1681 tggcgaaagc caaagaacgg atcattatgg attatccctc cgtaacacac taaaaaccga
     1741 agattgtgag actgaatatc ggtccgctga cgattgaatt gtcgggagtg acagaacagg
     1801 agattcctgt taacagccgt ctgttcctcg accgtaaacc cgctgataaa agggcagacc
     1861 ggcactatac attccatttt gtcggccgtc tgcctttgcc gtccaacgac tggcaggcca
     1921 tattccgacg caacgacatc gtgatcttcc gaaaggaaga acgggaaaca cgcctgctgg
     1981 ctataggaaa tctgaacgcc tgctatgcgc tctatcagga aaaagacgaa aggaatgccg
     2041 acatctattt catcgaagga ctgaaaagag aactgcaaac agataccctg ttcatttcct
     2101 gcctgtgcct ggaacgtcct ttatctgtcc agggatgtta catactacat tgtacttttc
     2161 tggattatcg tgggcaagcc atcttattca gtggtcctag cggcattggc aaatcgacgc
     2221 atgccaacct gtggtgccgg catattcccg gcacccaggt actcaatggc gaccgtgccc
     2281 tgctctgtcc acttccaaac ggcgactacg agataacggg atggcctgta tgcggttcca
     2341 gcggtatctg tcacaatgaa cgccgcccgt tggaggccat tgtattcatc gaacaggcat
     2401 ctgataacac catccgtccc cagacagcca tgaagcattt caaagctctc tgctcgcagg
     2461 ttacaatcaa ctggtggaat ccaaagctca ccggcaaagc actcgacgat ctgcaggttt
     2521 tgaccagaca gacaagcatc agcacctatg cgtgcaacat gaatccggaa gcagccttca
     2581 ccctgcacag gtatctgacc aaactggaaa ttatccgata atgtgaaata cgccccatta
     2641 tgaagactgt cgatacgaaa gaatacatat ccatgctgcg taccctcatt gaggaaggaa
     2701 agcaggtgag catgatcatc tcgggcagca gcatggctcc attcctgatc cacgcaagag
     2761 accacatctg cctgaaaagc ccctccggtg aacttcggaa aggagatatg gtgttctatc
     2821 agcgaagcaa cggtgaatat gtcatgcacc gtatttataa tgttaaaaat gaagaatatt
     2881 atcttatcgg tgacgcccag actgtcatcg aaggtccaat tcaaagagaa cagattttcg
     2941 ccatcattat caaggtgaag cgaaaaggga aatggatagt tccagaagat ttccagtgga
     3001 aattcttcgc ccacatatgg ccgaacataa ttcctttacg caggaccatc attaaaacat
     3061 atcgtttttt caaaagatga aaagaaccaa agaatttatc aaacgaaaca tagccggaga
     3121 aatcgtactg gttccttccg gacagaccgc ccgagagttc aacggaatgg tcaccctgac
     3181 cgaaaccgga gaatttatct gggagcatat cgaagaagca gaaagcttca accatctagt
     3241 actgttgatt ctggaggaat acgaagtgga taaagacacc gcatcgcaag atgccgcagg
     3301 atttatcatg caactgctgc aagccggcat gatccgtccc acaggtataa actggtaaac
     3361 agtaatctgt tcaattcaga tatgacaaac aatacaataa gaaatgttag aagagagatt
     3421 cgttttcttc gcgagaagcg ccggatctgt aaaaaatgtt agatcaggta agttcaagac
     3481 cctatgttat cagcggataa tagaatgaac ttacatttta ttccccatta catctgcctg
     3541 tgaaggtcga tgtaatttta actataaata ggataatgca ataatataaa gacaatgaga
     3601 ctcaattcta atttaattct tcgccaagta ggtggagaat atatgattgt caatccgttt
     3661 tctgaaacca tggatatggc acaggtctat tccttgaatg aaacagccgc ccggttatgg
     3721 aaacaattgg aaaacaagga attcacggta gatgaagccg gagcactgct gtgcaatgaa
     3781 tatgaagtaa ataaagatac agcccgaaac gatgccaacg agctgtgccg acaatggtta
     3841 gaaactgggt tagccataga ataagacaaa aagatgatct cagccccatt acaaaaggct
     3901 ttcatgcttt tgctaaggca aggactgtgg gaccggcagg aagactgttc cgcccttttt
     3961 cctctagatg aaaaggaatg gaatgaaatt cacagcatgg caagaaaaca aaccgtacaa
     4021 ggtattattt acgatggcat ccgcctgttg ccgactgaag ccgtacctcc ccggaaggta
     4081 ttgcttggct ggatggtgga agttgacacc ttggaacggg tgaaccggca acaccgggaa
     4141 acgattaaag ccctccaaca gatttatgta caatcacctt ctatcccttt cctgctgcta
     4201 aaagggatag ggacagctga cttctaccct catccggaac atcgcatagc cggagacatc
     4261 gacctgtggt tcggaaacaa gacacaaacc gaacaagcca accaacggat ggaaaaatta
     4321 ggattaccgg taaaaagagg aaccaatggt gaggcttcct gtctgataaa cagagttctg
     4381 attgaacatc acagcaggct gatagagttg cacaaccctt tcctccaaaa agaaatccgc
     4441 caatgggaag cgggggtctt taccaacagc caaggcaaac ttccgagcga agcgaatcat
     4501 ctattacttt ccacccacat attgaagcat cttatcaatg aagggatcgg actacgacaa
     4561 ttgtgtgata tagccatggc ttttaacgca ttacattctg ttacaaacaa aaacgaatta
     4621 gagtgtatct gtcgcaaatg gcacattcac cggtggaacc ggttacttta tgccctattg
     4681 ataaaatatc ttggcgtgcc ggccgacctt ttaccattca gtaccagtct ctgtccggac
     4741 aagttaatgc aagagatttg ggaaagtggc aattttggac atggagacga acgttacggt
     4801 gaacgtccca ccgggaaatg ggcgaacaaa cgatacacgt tgaagcggat ctttcacaaa
     4861 acgcacttat cgttaggtta tgctttcgac gaaactttct ggtggctggc cggattagcc
     4921 ctcttacgtt tcaaggaaat gataaaaaag aaatgaaaga attgctgaaa aaatttttgc
     4981 agaagctcac acgggagaat ctgagcaata catgtcagtt aggatggaaa gctttcaaat
     5041 gggttatgca ggtaacagaa ggataccatt ggctcatcac cttctctatc ttttcgggta
     5101 ttttcggagt ggtcatgtca ttggtcaatg tggccatgtc caaatggatc atcgatgtag
     5161 ctaccggagc acaggaaggg aatatttacc tggtagccac aatagtagcc ttatccttcc
     5221 tgctgggtat ggggataaaa cttgtatctc cctggatttt tggcaagatc aacatgcgca
     5281 tcagtatccg catgcaaaat tcgctgtccg acgccctaat gatgtgttca tggaaaggag
     5341 cagggaaatg gcacacaggc gacctgctga cccgtatcag cagtgacgct tccgaagtgt
     5401 tgggaatggg aatgggcatt ctacccaacc tgctggttac cggcttgcaa ttggcaagct
     5461 cttttatcta cttgtggatt cttgacgcgc gtttagcttg gttcatactg ggagtcaccc
     5521 ctcttgtttt attgtcaaag atttatttca gaaaggtccg ggaactgagc tgtgcccaaa
     5581 aaaagatgaa cagcgagatg ggtaccgtca tgcaagaaaa tctgtccaaa cggattctag
     5641 tccgctcgct cggagccacc aactaccgga aacagaaatt acatgaaaca caagagaagt
     5701 tgttcaaatt gggaatggaa caaatcaaat tttccacttt tacgcaaggg gtcatgggat
     5761 ttacatttgg aggagggtac ttatgtgcat tcctttgggg tattttccaa ctgcataacc
     5821 acgagataac attcggaaca atgacagcct ttcttcaact ggtcggacag gtacagggac
     5881 cttttttagg gttaatatcc atccctccca gtctgatacg gggatggacc tccgtggaac
     5941 ggttaatggc cctctttgaa gatgtagaac cggacgaaca cccggtctac atagaccaac
     6001 cactgacact gaactttcgg aaagtgtctt ttggctatga agagggacag ccggtactcg
     6061 accggtttac agctgccttt catccgggaa gttccaccgc catagccgga cctaccggaa
     6121 caggaaaaac gaccattatc cggctgatac tggctttggt ttatccggaa aagggacgca
     6181 tcgatttgac aactgatgac ggacggacac tcagtgtgac ccccgattta cgcatcaact
     6241 tcgtctatgt gccccaagga aatacgttgc tgagcggtac catccgggag aatttatggc
     6301 tgggtagtcc gggagcagac gaagaggctc tgcataaagt catccggctg gcctgcgctg
     6361 aatttgtgtt cagtctgccg gaaggactag ataccaagat aggggaacat ggatatggct
     6421 tgtctgaagg acaagcccaa cggattgcaa tagcccgcgc actgttgcgt cccgggcgga
     6481 tctggctgtt tgatgaagca tcatcggcac ttgacaccga gaccaccaca cacctcatgg
     6541 acaatttgtt gcaatgggga aagaataaca cattaatatt tgtgacacac gattcacgac
     6601 tgatggaacg atgtgaccaa gtgattcata taaaggaata aaaaacaatt aattataaaa
     6661 caatggataa aacaatcaaa ctggcctgtc tgttggcaat aatcattttt agttcgtgcg
     6721 cttcacgcaa agattttgtc tatttacaag atatggatga actacaggaa tatcctatgg
     6781 ttcaaaaata tgaagccatc atccataggg atgacagatt gagtattatt gtgaacagca
     6841 aaaacccaga actgtccctg cctttcaata tgtccggaag cagaagctat tctgtagaag
     6901 cagacggaag catttccaac aatgaagtgg gggtattaag tgatgaaaaa gaaaaaggtt
     6961 atttagtgga tatcaacggg aatatagact ttcctgtgct gggacaactg catgtggaag
     7021 gactgacccg ccgacaatta accgaactga taaaaaaacg actgatcaac gaagaattgc
     7081 tgaaagatcc tatggtcacc gtcaatttct tgaacttcaa attctccgtg ctaggagaag
     7141 ttggacatgt aggaaccttt gaagtgaaag gcgaccgcat cactctttta gaggctcttg
     7201 ccatggctgg agacctgacc ccccgatccc gtctggaccg tatcgccgtc atccgcgaat
     7261 atgggaacaa gcgacgaatc ctgttccacg acatccgcag caaagacatc ttcacgtcgc
     7321 cttactatta cctgcaacag aatgacattg tctacgtaga acctaccaac atgaaggcca
     7381 ccgaacaagc ccagagaaaa ctgagcacat ggagtatgat cctgtccttc atcaccacaa
     7441 tcacctcgct ggtattgctg actactaaat aaaaaagaaa cgacatgata agaatgagtg
     7501 aacaaaaaga tatgtcggga gataagacct taagcggggg aggattcaat atcaaccccg
     7561 ttgacatcat catgtacctg ttgtccaaat ggtactggtt tgtattgtcg gtcagtctgt
     7621 tcggcggata tgcatggtat caatatgcca aacttccctt tatctattca cggtcagcca
     7681 ccgtcatgat aaaggacgcc tattcaaaca acatcggtcg cgggctggac cgttttaaca
     7741 cctattcata taccaatgta tccaatgaga tcctgcaatt ccagtcacac aaactcatgc
     7801 gcgatgtggt gaaccgtctt cacgccaatg tatgctacct catcatggat gacttgcgtg
     7861 aggaggaact ttatacgcaa gcccctgtca aggtttcatt cccggaagaa gaggatcatc
     7921 ttgatttcag cctgacagtc agaatccaga acaggaagca agtccggtta tccgatttct
     7981 cgacagacgc cacaagtata acgctaacag ccaatctggg tgacaccatc caatcgccca
     8041 taggaaaaat agtggtctca cccaccttat attatacaga caagtggttc aatacaccaa
     8101 ttacgatacg ccggcagagt acggacacaa tggccagcct gttcagaagc aacctgaaca
     8161 tcagtcaggc cgagaatgat gcctccatcc tctacctgtc actccgtgat tactccaccg
     8221 cccgtgccga agatgtactc aatatgctga ttacagtgta taatgaagag actatcaaag
     8281 ataagaacca gatagccatc aatacctcca acttcatcaa cgagcgtttg gtcatcatcg
     8341 aaaaagaact aggaggcgtg gaaaacgaac ttcagtctta caaacaaaac aatgatatta
     8401 ttgatatcgg ttcggccgct tccatgtcca tgtcagacaa acggcagtac agctcgacca
     8461 ctcaggaact ggaattgcag gcacgcatgg cacgctacat caagggctac ctagtggacc
     8521 catccaaaga gactgagctt atcccttcaa acaccggcat agccgacatc aacattgaaa
     8581 cccagatagc ggcctacaac gccaacaagt tgaaacggga caaactgata gaaggaagca
     8641 gtgacaaaaa ccccatcgtc caggaactga acaagaatct gattgccatg cgacagaata
     8701 tcatccgggc catcgacaac atgattgtca gcatcgatgt gaaactgaac gaggcccgaa
     8761 gcagggccgg agaagcccag tggcgggtga ccaacatacc cagacaacag caacagatgc
     8821 tttctatcga acgtcagcaa cgcatcaaag aggaacttta cctctatcta ctgaacaaac
     8881 gcgaagaaaa tgcgctgagc caggccacca ccgaaactga cgcccgtgtg ctcgatcctg
     8941 ctggaggagg ggatgctccg atttctccca acggacgcag catgatcatg gcaggtgtca
     9001 tgaaaggaat cgccctgccg gcaattgtcc tgctattgtt cctgttcttc gatacccgca
     9061 tacgcaaccg caaggacatc gaggatgttg taaccgttcc tttcttaggc gaaataccca
     9121 aggattcatc caaaaggaag atagagaata aaaaaacagc gcatggcatc gctgtccgtg
     9181 cccaggggcg tgacattgta tcggaagcct tccgtataat acgcaccaat atggatttta
     9241 tgcgtgtcaa gtcaaagaac atgcaagtcg tcactttcag ttcgttcgga ccgggtgccg
     9301 gcaagacata cgtatccagc aatctggcgg ccagtttcgc gcaaaccgac aagaaagtca
     9361 tcctgattga catggatatc cgtaaaggga ctttgacttc acatacccgt cttcatacag
     9421 aagaaaaagg aatgacctcc ttcctggcag gcaaggccac gacggatgaa atcatcaagc
     9481 acaacgaaat ctgtgaaaac ctagatttca ttccggccgg tcccatcgca cccaacccat
     9541 cagagctatt gctcagcgaa caattggaag tgatgattgc cgaactgcgt aaccgttatg
     9601 actatatctt tgtcgacaat gcgcctgtag gagtagtggc cgatgccgcc atcaccaacc
     9661 gcatagccga cttgaccatc ttcgtggtac gggttggcaa gctagaccgc cgcatgttgc
     9721 cggagttgga aaaaatatac cgtagcggac aattgaacaa tatgtcgtta gtacttaacg
     9781 gtgctatagt aaaaacaagc ggatacggag gatacggcta cggttacgga tatggctacg
     9841 gttatgtgga tggttccgaa tcaagctgga aacgattgtt caaaaagaaa tcctgaaacc
     9901 ttaagaagaa agatgtttgg tatattcaag tccaaataca atttgattaa ttctggttta
     9961 atgaagggta tgaccgatat ccactcccat gttcttcccg gagtggatga cggttcaccc
    10021 gacataaata ccagtctgtc cctgctacgc tatatggaat ccatagggtt acgggaagtg
    10081 tggctcactc cccatatcat ggaggattat cccacgctga acaagaagct gcagcaacag
    10141 ttcgacgtgt tgaaggcagc ctattccggc ccgttgaatc tgcggctgtc ttctgaatat
    10201 atgatggatg ccgcttttac aaacaagttg gatggagaag tgctaccttt gggcagcagc
    10261 cacctgctgg tcgaaacatc ctacatgtac cctcctcccg gtttgccgga tatcctgatg
    10321 aaaatatgga atgccggtta tcaaccggtc atcgcccacc cggagcgtta cctgtacatg
    10381 gaagaaaaag attaccttct gctgaaagag aaaggttaca gctttcaact caatctgatg
    10441 tcactgagcg gttactatgg cccgcacccc aaagtggtca gcgaaaagct gttaaaacaa
    10501 aaaatgtacg attttgtggg tacggacctg caccatttgg agcgttaccg gcccatgctt
    10561 gaccaattga ggttgacccg aagacaactc gaagctttag aaggtctgat tgccaacaat
    10621 gcgcgtattt aactgtctgt cgggaagtat cctgtgcggt ctgacactgc tgttgatatt
    10681 tctcccctgc ttcactcccg agtgggccgg aaattttatc ctcatcagtc tatcggcaat
    10741 tcctatatgc atagccgatg gaattatttt cgcgattctg ctctggaggc acaaccgctg
    10801 gtggatgctt tacttgtttt tgttattggg gagtctgccg gttctagcat gtcagttccc
    10861 gtttcatttc ctgcacaaag aaaaagtgct ggattccaat cagctgaaat tggtttgctg
    10921 gaataccgaa gggttcaggc tgaacaaaga cactctgaca aaggccgccc atagcattcg
    10981 tgtcctgcaa cccggcatcg tctgtctgca agaacgtcct cataccaatc ttctggcatg
    11041 ggacaccatt cgggctgctt ttcctgatta tccctattgc atcatcaact cgcgggaaga
    11101 tgaagtcctt aatctggccg tcttcagccg ctggcctatc ggaaacgttc aagagtacta
    11161 ctttccaaac agctacaaca aaatacttca agcggatatc cagatgacag ggcaaacttt
    11221 ccggttattc aacgtccatc tgcaaactac aggcatgaat gaatcatact caatgaaaga
    11281 cagatttcag gcgatgcgcc accacaccgt ccagcgtaac cggcaagccg atctcttgac
    11341 aaaagccatc gccgagagcc cttatccggt catcgtgtgc ggtgatttca atgacacacc
    11401 tgcctcgtat gcttaccgga aaatcagccg gttactacag gattgcttcc tccaggccgg
    11461 gcagacatgg agcggcagtt accaatgctg gggcggtttt ttacgaatag attatacgtt
    11521 ctgttcacct gcattccaag tgaatcgtta cctactgatt tccaatccct ggagcgacca
    11581 caaacagcag cactgtgtgc tctatctgga caaatgctcc tgaaaaaaca agatctcaaa
    11641 aaaatgacta aagaaaactg gacaatagaa ataaaaccaa agaaaaaatg gctggatata
    11701 gacctgaaag gtatatggcg gtaccgtgac ctatactata tgtacgtgaa acgcgacatc
    11761 gtcaccgtat acaaacaaac cattctgggt cctctctggt tcctcatcca accaatcttc
    11821 actaccgtaa tgtatatgtt catattcggc ggcttggcag gtatctcaac ggacggagta
    11881 ccacagcctt tgttctacat ggcaggtatc atgctgtgga attatttcag ttccgcgttc
    11941 aacgtatcct ccaatgtgtt cactgccaat gcgggtgtgt tcggcaaagt ctatttcccc
    12001 cgtctagtcg tgccgttgtc cggcatcacc tccaacctga tcaagttcgg aatacaactg
    12061 ttgttgttca ttgccatgta tctctatttt tatgtgaaag gagcttcact gcatgtcaat
    12121 gccgccctgc tgttatttcc gttcctgata ttcctaaccg cattccatgc catgtcgtgg
    12181 gggttgatca tatcagcgct gaccaccaaa taccgtgacc ttacccagtt ggtcactttc
    12241 ggcctgcaac tatttatgta tgccactccg gtcatttatc cgctaaacgc agctccggaa
    12301 aaataccgtg acatcatcgc gctcaacccg ttgacaccca tattcgagac ctttaaatac
    12361 agctgcatgg ggtgtggttc acttgattgg ggcggattgg catatagcac tttgtttatg
    12421 ctctccaccc tgttctgcgc agtagtcatc ttcagccggg tggaacgcaa ttttatggat
    12481 acagtgtaag cagcagaatt aaaaaaagag aataagaatg aacgatatag caatccggtt
    12541 tgaccatgtg ggcaaactct acaaactcgg tctggtcggc accggcacac tgagccacga
    12601 cctcaaccgc tggtggaaaa cgaccattct ccgccaggaa gacccctatc tgaagatagg
    12661 cgaaaccaac gaccgcagca agaaaggcgc gtcggaatat gtctgggcgt tgaaagacat
    12721 caccttcgat gtgcatcaag gcgatgtagt aggcattatc ggaaaaaacg gtgccgggaa
    12781 gtccaccttg ttgaaacttc tgtcgcgtgt cacctcccct accaccggag ccatccgtgc
    12841 ccgtggccgc attgcctctc tcttggaagt cggtaccggt ttccatccgg aactgaccgg
    12901 ccgtgagaac atctacatga acggctccat catgggcatg actcgccacg aaatctccca
    12961 caagttggac gagatagtcg actttgccgg tgtggaacgc tatgtagata cccccgtaaa
    13021 acgctattcc agcggcatga ccgtccgtct gggctttgcc gtagccgctt ttctggaacc
    13081 ggaaatactg gtagtagatg aggtacttgc cgtaggtgat gccgaattcc agaagaaagc
    13141 tatcggcaag atgcaggacg tgtcgaaagg cgaagggagg acggtgttgt ttgtgagtca
    13201 taatatggcg gcggtacgag ttctttgcaa acaagggata gtactcaaca acggaactgt
    13261 agcctatacg ggaagtatag aggattgcgt taattatttt ataggtaata at
//
