LOCUS       c00044_gnlPro..        10408 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMBODDLG_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:20:26
            Original ID  :: gnl|Prokka|BMBODDLG_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10408
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10408
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[81:9951]"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      82..9951
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /neighbourhood="10000"
                     /product="NADH_dehydrogenase_I"
                     /protocluster_number="1"
     cand_cluster    1..10408
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Oxidored_q4 and Oxidored_q6 and
                     Complex1_30kDa and Complex1_49kDa and NADHdh and
                     Oxidored_q3 and Oxidored_q2 and minimum(4, [Fe-2S_thioredx,
                     Fer2_4, Fer4_7, Molybdop_Fe4S4, Molydop_binding,
                     NADH-G_4Fe-4S_3, NADH_4Fe-4S, Proton_antipo_M,
                     Proton_antipo_N, SLBB]))"
                     /kind="single"
                     /product="NADH_dehydrogenase_I"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10408
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NADH_dehydrogenase_I"
                     /region_number="1"
                     /rules="(Oxidored_q4 and Oxidored_q6 and Complex1_30kDa and
                     Complex1_49kDa and NADHdh and Oxidored_q3 and Oxidored_q2
                     and minimum(4, [Fe-2S_thioredx, Fer2_4, Fer4_7,
                     Molybdop_Fe4S4, Molydop_binding, NADH-G_4Fe-4S_3,
                     NADH_4Fe-4S, Proton_antipo_M, Proton_antipo_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(82..1503)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_1"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.8e-72,
                     bitscore: 233.5, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDITAILHMHAELSLTAVFILMFLLDLFLPAPQRHWLRPMACIL
                     LTIQLLANLWPEEVTLFGGMYHSTPMASVLKSILTIGTILVFLQADPWLKREDTRHKQG
                     EFYILTLSTLLGMYFMVSAGHFLLFFLGLELATIPMACLVAFDKYKGHSAEAGAKFILS
                     ALFSSGIFLYGISMIYGTTGTLYFEDIPAELTGTPLQVLALVFFFSGLAFKLSLVPFHL
                     WTADTYQGAPTTVSAYLSVISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIA
                     NLFAIRQNNLKRFMAFSSISQAGYIMLAVLAGTPQGMASLVYYIVVYIAANLAVFGVIN
                     TIEQHTHGKIEREDYNGLYKTNPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSG
                     YYLIVFIALVNTIISLYYYLLIVKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFALG
                     IISGVYQLLSDTSIL"
     CDS             complement(1534..3015)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_2"
                     /sec_met_domain="Proton_antipo_M (E-value: 7.6e-70,
                     bitscore: 224.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILSFFIIVPLLMLASLWASRSINQVRGVMVVGSSILLALSVYL
                     TIDYIELRQAGATGEMLFTASTVWYAPLHICYSVGVDGISVAMLLLSSIIVFTGTFASW
                     KLQPLTKEYFMWFTLLSVGVFGFFVSTDLFTMFMFYEVALIPMYLLIGVWGSGRKEYAA
                     MKLTLMLMGGSAFLLIGILGIFYGAGGETMNLLEIAKLHIPHEMQRIFFPLIFLGFGVL
                     GALFPFHTWSPDGHASAPTAVSMLHAGVLMKLGGYGCFRVAMYLMPEGAAMWGDVFLIL
                     TTISVVYGAFSAVVQTDLKYINAYSSVSHCGLVLFALLMMTRTSCTGAILQMLSHGLMT
                     ALFFALIGMIYGRTHTRDVRLMGGLMKIMPFLAVGYVIAGLANLGLPGLSGFVAEMTVF
                     VGSFQNDDTFHRVCTLVATTSIVITAVYILRVVGKILYGKVLNPEHLKLTDATWDERAA
                     VICLIACVAGLGLAPFWISDLISNSVEPIISQLLN"
     CDS             complement(3069..4970)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Proton_antipo_M"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_3"
                     /sec_met_domain="Proton_antipo_N (E-value: 1.7e-26,
                     bitscore: 81.8, seeds: 433, tool: rule-based-clusters)"
                     /sec_met_domain="Proton_antipo_M (E-value: 1.2e-82,
                     bitscore: 266.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHTILILILPFLGFLILGLAGMRMKNGLAGAIGTVSLAGVALLS
                     YLTAFNYFAGGRTAEGVYPTLTPYNFEWLPFTTNLHIDMGIMLDPISVMMLVVISTVSL
                     MVHIYSFGYMKGEKGFQRYYAFLSLFTMSMLGLVVATNIFQMYVFWELVGVSSYLLIGF
                     YYTKKEAIAASKKAFIVTRFADLGFLIGILIYGYYAETFSFTPQLQVLAVAGSMIPLAL
                     GLMFIGGAGKSAMFPLHIWLPDAMEGPTPVSALIHAATMVVAGVYLVARMFPLFIGYAP
                     EVLHWIAYIGAFTAFYAASVACAQSDIKRVLAFSTISQIGFMIVALGVCTSMNPHEGGL
                     GYMASMFHLFTHAMFKALLFLGAGCIIHAVHSNEMSAMGGLHKYMPVTHWTFLIACLAI
                     SGIWPFSGFFSKDEILTACFQFSPVIGWIMTGIAAMTAFYMFRLYYCIFWNGEWKGHSH
                     ESGLGAHTPHEAPLTMTFPLMFLAAITCVAGFIPFGNLISSNGEAYTIHLDMQIAATSI
                     IIAIASIALATWMYAGKKQPVANYLAHTFPRLHTAAYHRFYMDEIWLFVTKKIIFRCIS
                     TPIAWWDRHVIDQFFNFTAWSTHATADEIRDMQSGNVQQYSIWFLAGALILTLILLI"
     CDS             complement(4973..5272)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_4"
                     /sec_met_domain="Oxidored_q2 (E-value: 3.5e-22, bitscore:
                     67.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYYLVVSTFMMFAGIYGFFTRRNLLAMLISVELILNSVDINFAV
                     FNRYLFPEELEGFFFALFAIGVSAAETAVAIAIIINIYRNVRNIQVKNLNEMKN"
     CDS             complement(5287..5790)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_5"
                     /sec_met_domain="Oxidored_q3 (E-value: 3e-35, bitscore:
                     110.6, seeds: 708, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLQLIVFIVLALFIAVCSVLAVTTSRILRAATYLLFVLFGTAGI
                     YFQLNYSFLGAVQLLIYAGGITVLYVFSILLTSSQGDKAERLKNGKMVAGAISTIAGLA
                     ICLFVMLKNEFLPSHFVHGELDVRTIGHALMGMEKYQYILPFEVISVLLLACIVGGILI
                     ARKR"
     CDS             complement(5806..6258)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_6"
                     /sec_met_domain="Fer4_7 (E-value: 2.5e-14, bitscore: 43.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.8e-09, bitscore: 26.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-06, bitscore: 16.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEKHSYIKGLLHGIGTLLTGMKVTGREFFTPKVTEQYPENRAT
                     LKISPRFRGRLIMPVDENGNNKCIACGLCQMACPNDTITITSESVTNEETGKKKKILVK
                     YEYDLGACMFCQLCVNACPHDAIRFDTEFENAVFDRSKLVLTLHKK"
     CDS             complement(6258..7334)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: NADHdh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_7"
                     /sec_met_domain="NADHdh (E-value: 5.9e-121, bitscore:
                     392.8, seeds: 435, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDFSIVTQWVHSLLTSFMPEELAVLIECIVIGVCIMLAYAVIAI
                     IMIFMERKVCAAFQCRLGPMRVGPQGTIQVFADVFKMLIKEIITIRHADKFLYNLAPYI
                     VILASIMAFSCLPINKGMEVLDFNVGIFFLLAASSIGVVGILLAGWSSNNKYSLIGAMR
                     SGAQMISYELSVGLSILTIVILTDTMQLSEIVERQADGWFLFKGHIPALIAFIIYLIAG
                     NAEVNRGPFDLPEAESELTAGYHTEYSGMHFGLFYVAEFVNLFIIAAVATTIFLGGWMP
                     LHIPGLDGFNAIMDYIPGFIWFFGKSFFVVWLLMWIKWTFPRLRIDQILTLEWKYLVPI
                     GLCNLLLMVIIVVFKLHF"
     CDS             complement(7458..9017)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_30kDa"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Complex1_49kDa"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_8"
                     /sec_met_domain="Complex1_30kDa (E-value: 5.7e-39,
                     bitscore: 123.1, seeds: 586, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_49kDa (E-value: 1.4e-64,
                     bitscore: 207.3, seeds: 265, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKIEIPAEKLHEEMLKLRQGKHMDFLRSLTGMDWGEEGLGVVY
                     HLEDTKTRENIVVSTRTTNREKPELPSVSDIWKGAEFNEREVYDYYGIRFIGHPDMRRL
                     FLRDDWVGYPLRKDYDENLNPLRMTNEEAVDTTQYIEVQHDGSVIEKRETIFDEDEYII
                     NIGPQHPATHGVLRFRVSLEGEIIKKLDVHCGYIHRGIEKMCESLTYPQTLALTDRLDY
                     LGAHQNRHALCMCIEQAMGVEVSERVQYIRTIMDELQRIDSHLLFFSCLCMDMGALTAF
                     FYGFRDREKILDIFEATTGGRLIQNYNTIGGVQADIAPDFVQKVKEFIVYLRPMLKEYH
                     EVFTGNVIAQERLKGVGVLSQEDAISFGATGGTGRASGWACDVRKRHPYAMYGKIDFRE
                     IVHTEGDCFARYMVRMEEILESMNIIEQLIDNIPEGNYQEKMKPIIRVPEGNYYAAVEG
                     SRGEFGVYLESHGDKFPYRMKFRATGLPLVSAMETMCRNAKIADLIAIGGTVDYVVPDI
                     DR"
     CDS             complement(9014..9610)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q6"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_9"
                     /sec_met_domain="Oxidored_q6 (E-value: 2.4e-25, bitscore:
                     78.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVKKPTIKSIPYEDFKNNEYLENMVKQLNESGTKVLVGCLDDLI
                     NWGRSNSLWPLTFATSCRGIEFMAVGAARYDFARFGFEVARASPRQADMIMVAGTITHK
                     MAPVLKRLYDQMADPKYVIAVGGCAISGGPFKKSYHVLNGVDKILPVDVYIPGCPPRPE
                     ALLYGMIQLQRKVKLEKFFGGVNRKENEPQNPEQA"
     CDS             complement(9601..9951)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NADH_dehydrogenase_I: Oxidored_q4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_10"
                     /sec_met_domain="Oxidored_q4 (E-value: 2.4e-40, bitscore:
                     126.4, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYFTLLVVVILTAIALVAVALGIARAISPRSYNSQKGEAYECGIP
                     TRGRSWMQFKVGYYLFAILFLMFDVETVFLFPWAVVVQDLGVYGLFSILFFLVILVLGL
                     AYAWKKGALEWK"
     CDS             complement(10055..10408)
                     /locus_tag="ctg44_11"
                     /transl_table=11
                     /translation="VYILLFLLFTITVDQDHYTVEPTDLHPQTSCYQQQQDPCKRTVDF
                     LFTNNFADMPQIAISLDNPSTSKFKCIVRILTALSELKKQELQTNRIVCHTFHSLYTDA
                     VDYYIYALRRIII"
ORIGIN
        1 attctgcctc taaagtaaaa gaatattgat catagaaata caataatcat ttcagttgtg
       61 attcttcttg taactaaaat tttatagtat tgatgtatca cttaatagtt gatatacccc
      121 acttataatt cctaaagcga atatgccggc tacacatacc aacagactga tgcgcatcgg
      181 agttgctgta cgaaaattgc cgataggatc ttcattaggt gtgatgaaca tggcttttac
      241 aattaacaaa taataataca atgaaatgat tgtattgacc aatgcgataa atacaataag
      301 ataatatcca ctatggaatg ctgccatgaa tacaaagaac ttactgaaga atccggcaaa
      361 tggcgggata cctgccaatg agaaaagagc aagtgtcatg accatagtta gtttggggtt
      421 ggtcttataa agtccgttat aatcttcgcg ttctatttta ccgtgggtat gttgttcaat
      481 ggtattgatg acaccgaata cggcgagatt ggcagcaatg tatactacta tataatatac
      541 tagggatgcc atgccctgcg gagttccagc cagtacagcc aacattatgt agccggcttg
      601 tgaaatacta ctgaaggcca taaagcgttt cagattgttt tggcggatgg cgaacagatt
      661 ggctatagtg atggtggcta caatgataat acatagtatt tcactccatt gttcagtcat
      721 tggcccaaat actttcatta aaataatcat taaagcaaaa gcagctgcgc cttttgaaat
      781 aacggacagg taagcgctca ctgtagtcgg tgcaccttga tacgtatctg ccgtccacag
      841 atgaaaaggt accaagctta atttaaaggc tagtccggag aagaagaata ctagtgcaag
      901 aacttgtaat ggagttcctg tcagttcggc agggatatct tcaaaatata aagtacctgt
      961 tgtcccataa atcatggaaa taccatagag gaaaataccg ctggagaata aagctgaaag
     1021 aatgaatttg gctccggctt cggcactatg tcctttatat ttatcgaaag ctacgaggca
     1081 agccatagga atggttgcca attccaatcc aaggaagaat agcaggaagt gccctgcact
     1141 taccatgaaa tacataccca gcaaggtact gagggtaagg atgtagaatt cgccttgttt
     1201 atggcgggtg tcttcacgtt ttagccaagg gtctgcttgt agaaaaacca gtatggtacc
     1261 tatggtcagg atgcttttca gaacagacgc cataggggtt gaatggtaca tgccgccgaa
     1321 taaagtcacc tcttccggcc ataggtttgc taagagttga atggtcagca ggatacatgc
     1381 catggggcgt aaccagtgac gttgtggagc cggtaaaaat aaatctaaca gaaacatcag
     1441 aataaaaacg gctgtcagac tcagttcggc atgcatatgg agtattgcag ttatgtccat
     1501 cattgctatt ttttaatttt taattctcaa attttaattt aataattgac ttatgattgg
     1561 ttctacactg ttactgatca gatcgcttat ccagaatgga gccaatccta aacctgctac
     1621 acaggcgatg aggcagataa cggctgctct ttcatcccaa gttgcgtctg tgagtttcag
     1681 atgttcggga ttcaaaactt tgccgtaaag gattttacct actacacgca ggatataaac
     1741 tgcggtaatg acgatacttg ttgttgccac tagggtacat acgcgatgga atgtatcatc
     1801 attttggaaa gaacctacaa agaccgtcat ttcagcaaca aaaccactta gtcctggaag
     1861 tcccagatta gcaagaccgg caataacata acctacagcc aggaaaggca taatcttcat
     1921 caaacctccc attaatcgga catcacgggt gtgggtacgt ccgtatatca taccaataag
     1981 ggcgaagaac aaagcggtca ttaatccgtg actcaacatt tggagaatag cacccgtaca
     2041 actggtgcgt gtcatcatca gcagggcaaa gagtaccaat ccgcagtggg atacggatga
     2101 ataggcattg atatatttta agtcggtttg taccacagca ctgaatgcac cgtaaactac
     2161 agaaatagtg gtcaatatca ggaatacatc tccccacatg gccgcacctt caggcatcag
     2221 gtacatagca acacggaaac atccgtaacc tcctagtttc atcaataccc cggcgtgaag
     2281 catagaaaca gcagtcggtg cggaagcgtg accatcggga ctccatgtat ggaaagggaa
     2341 caaagctcct aagactccga accccaagaa gataagcggg aagaagatgc gttgcatttc
     2401 atgaggaata tgtagtttgg cgatttccag caaattcatt gtttcaccac ctgcaccata
     2461 gaaaataccg agaattccga tcagtagaaa tgcagaacca cccattaaca ttaatgtaag
     2521 tttcatggcg gcgtattctt tacgtccgct tccccacaca ccgatgagca gatacattgg
     2581 aatcagggct acttcataaa acatgaacat ggtgaacagg tctgttgaaa cgaagaatcc
     2641 gaatacccct acactcaata gagtgaacca catgaaatat tcttttgtca atggttgtaa
     2701 cttccacgat gcgaaagtac cggtgaatac aataatggaa ctaagtagca acattgctac
     2761 tgatataccg tctactccta ctgagtagca tatatggagc ggtgcatacc aaactgtgct
     2821 ggctgtgaac agcatctctc ctgtagcacc ggcttggcgt agttcgatat aatcaatggt
     2881 gaggtaaacg gataatgcca ataaaatgga agatccgaca accatcactc cgcgaacttg
     2941 attgatgctg cgcgaagccc aaaggctcgc gagcatcaac aagggaacta taatgaaaaa
     3001 acttagtatg ttcatctttt taaattaaaa attaaaaaat ggccatgcgg cggatttttt
     3061 attattcatt aaattaatag tatcagcgtc aatatcaatg cacctgcaag gaaccaaata
     3121 ctgtattgct gtacgtttcc actttgcatg tcacgtattt catcggcggt agcatgagta
     3181 ctccacgcag tgaagttaaa gaattgatcg ataacgtgcc ggtcccacca agctatcgga
     3241 gtactaatgc accggaagat gattttcttg gttacgaata accatatctc atccatatag
     3301 aaacgatggt aagcggctgt gtgcaaacgt gggaatgtgt gtgccagata gttggctacg
     3361 ggttgtttct tacctgcata catccatgta gctaaagcga tggatgctat agcaataatg
     3421 atacttgtag cagctatctg catatccaga tgaatggtat aggcttctcc gttactactg
     3481 atcagattgc cgaaaggtat gaatccggca acacaggtga tagcggctaa aaacatcagc
     3541 gggaatgtca tggtaagtgg agcctcatgc ggagtatgtg cacctagtcc ggattcgtgg
     3601 gagtgtcctt tccattctcc attccagaaa atacaataat aaaggcggaa catataaaat
     3661 gcagtcatgg cggcaatgcc tgtcattatc catcctataa caggactgaa ttggaagcag
     3721 gcggtcagaa tttcgtcttt agagaaaaaa cctgagaatg gccagatacc tgagatagcc
     3781 aaacaagcaa ttaggaatgt ccagtgagtg acgggcatgt atttatgaag tccccccatg
     3841 gcgctcatct cattactgtg tacggcatga atgatacatc cggctcctaa gaacaacaat
     3901 gccttgaaca tggcatgtgt gaacaggtgg aacatggatg ccatgtagcc tagtcctcct
     3961 tcatgaggat tcatggaagt acaaacgcct aatgcgacaa tcataaatcc aatctgagat
     4021 atagtggaga aggcgagcac acgtttgata tcgctttgtg cacacgccac actagcggcg
     4081 tagaatgcag tgaacgcacc gatataagct atccagtgca gtacttcggg cgcatatcct
     4141 ataaacaacg ggaacatacg ggctaccaga tatacaccgg ctaccaccat ggtagcagca
     4201 tggattaatg cactgacagg agtagggcct tccatagcat ctggtaacca gatgtgcaat
     4261 ggaaacattg cacttttacc ggcaccaccg ataaacatta gccccaaggc cagtggtatc
     4321 atacttccgg caactgcaag tacctgaagt tggggtgtga acgagaatgt ttcggcataa
     4381 tagccgtaaa tcaagatacc gatcagaaag cctaaatcag caaaacgggt aacaataaat
     4441 gcttttttac tggcggcaat cgcttctttc ttggtgtaat aaaagccgat aagtaaataa
     4501 gaagaaacac ctaccagttc ccaaaagaca tacatctgga aaatattggt tgctactacg
     4561 agtcccaaca tggacatggt aaacaggcta agaaatgcgt agtaacgttg aaagcctttt
     4621 tcacctttca tatatccgaa tgaatagata tgtaccatca gactgacggt ggaaataacg
     4681 actagcatca taacggaaat agggtcaagc ataattccca tgtcaatatg caagttcgtt
     4741 gtgaaaggta accattcgaa gttataaggt gtgagagtag gatagacgcc ttctgccgta
     4801 cggcctcctg caaaataatt gaaggcagtg aggtaggaaa gcaacgccac ccctgccagt
     4861 gaaacggtgc cgatggcccc tgccagcccg ttcttcatac gcatacctgc cagccccagt
     4921 atcaggaaac cgaggaaagg taggataagg attagtattg tatgttccat acttagtttt
     4981 tcatttcatt taagttcttc acttggatat tgcgtacatt gcggtagata ttgataatga
     5041 tagcaatagc tactgctgtt tcagccgcac ttacgccgat agcaaacaag gcgaaaaaaa
     5101 agccttccag ttcctcggga aagaggtatc ggttgaatac ggcgaagttg atgtctaccg
     5161 aattcagtat cagttctaca ctgatgagca tggccaataa attgcggcgg gtgaagaaac
     5221 catagattcc cgcaaacatc ataaaggtgg aaaccaccag ataatattcc atgtgtacca
     5281 taaattttat ctttttctag cgattaggat tcctcctacg atgcaagcga gtaataacac
     5341 gctgattact tcgaaaggaa gaatatattg atatttttcc atgcccatca gtgcatgacc
     5401 gatagtgcgt acatccagtt caccatgcac aaaatgagag ggcaagaatt catttttcag
     5461 catgacgaac agacagatag ccagtcctgc tatcgtagaa atagctccgg ccaccatctt
     5521 cccatttttc aatctctctg ctttgtctcc ttgtgaagag gtcaataaga tactaaatac
     5581 ataaagcact gttataccac cggcgtaaat cagtaattgt acagctccca agaatgagta
     5641 gttgagctgg aagtaaatac ctgctgtacc aaataaaacg aacagcagat aagttgctgc
     5701 acgcaagata cgtgaggtcg tgactgccaa taccgaacag acagcgataa acaacgccag
     5761 tacaatgaat acaattagtt gtagtgtcat aatatcgttt gttttttatt ttttgtgcag
     5821 ggtgagaact agtttgctgc ggtcgaacac agcattctcg aattctgtat cgaaccgaat
     5881 ggcatcatgt ggacaagcgt tcacacaaag ttgacagaac atacaggctc ccagatcgta
     5941 ctcatacttt accaatattt tctttttctt gcctgtttct tcgttggtca cagattcgct
     6001 ggtaatggtg attgtatcat tggggcaagc catttggcaa agtccgcaag caatacattt
     6061 gttattacca ttctcatcaa ccggcatgat aagccgtcct cggaaacggg gcgatatttt
     6121 taatgtggca cggttttcgg gatattgttc agtgacttta ggagtgaaaa actctcgtcc
     6181 tgtcactttc ataccggtaa gtaatgtacc gatgccatga agtagtcctt ttatatagga
     6241 atgtttttct tctttcatca gaaatgtaat ttaaatacaa caataattac catcaacagc
     6301 aggttgcaca aacctattgg gaccaagtat ttccattcca gtgttagaat ttggtcaata
     6361 cgcagacggg gaaatgtcca tttgatccac attaataacc atactacaaa gaatgacttg
     6421 ccaaagaacc aaataaatcc gggaatataa tccataatgg cattgaatcc gtctagtcca
     6481 ggaatatgta gcggcatcca tcctcctaga aagatggttg tggctaccgc ggcgatgata
     6541 aacaagttta caaattctgc cacatagaac aagccgaagt gcataccgga atattcggta
     6601 tgatatccgg cggtcagttc actttccgct tcaggcaagt caaacggtcc gcggttgact
     6661 tctgcatttc cggctatcag ataaatgata aaagcgatca atgcaggtat atgtccttta
     6721 aaaaggaacc agccgtcagc ttggcgttct acaatttcgc ttagttgcat ggtatctgtt
     6781 aagattacaa tagtaaggat gcttaatcct acagataatt cataactaat catttgagcg
     6841 ccacttctca tggctccgat taatgaatat ttgttattgg aactccaacc tgccagcaaa
     6901 atacctacta cgccgatact ggatgctgcc aataagaaga aaatacctac attgaaatca
     6961 aggacctcca tgcccttgtt gatgggtagg caactgaaag ccatgataga ggcgaggata
     7021 acaatgtaag gtgccaaatt gtacaggaac ttgtcagcat gtcggatggt gataatttcc
     7081 ttaatcaaca tcttgaatac atcggcaaat acctgtatgg taccttgggg acctacacgc
     7141 attggaccca agcggcattg gaaagcggcg cacactttac gttccatgaa aatcataatg
     7201 atagcaataa ctgcgtatgc caacatgata catacgccaa ttactataca ttctatgagc
     7261 actgccagtt cttcaggcat aaatgacgtg agcagtgagt gtacccattg ggtgactata
     7321 ctaaaatcga acataattta ataatgtgtc aatttgctaa tttgccaata ggcaaacttg
     7381 taattattta atttgttaat tctcagtctg ataaataatg cattcttcaa gtagtatatt
     7441 gaagaattgg cacattatta tcggtcaata tccggtacta cataatccac cgttccacca
     7501 atagcaatta agtcggcaat ttttgcattg cggcacatag tttccattgc tgatactaaa
     7561 ggtaaaccgg tagcgcggaa tttcatgcgg taaggaaatt tgtctccatg actttccaga
     7621 taaaccccga attctccgcg agaaccttcc acggcggcat aataattccc ttcgggcacg
     7681 cgtataatcg gtttcatctt ttcctgatag ttcccttcag gaatattgtc tatcagttgc
     7741 tcgatgatgt tcatactttc cagtatttct tccatacgga ccatgtaacg tgcaaaacag
     7801 tcgccttcgg tgtggacaat ttctctaaaa tctatcttgc catacatcgc atagggatga
     7861 cgcttgcgga catcacatgc ccaaccgctg gcacgtcctg tacctcctgt tgctccgaaa
     7921 gagatagcgt cttcctgtga aagaactccc acacctttca aacgttcttg ggcaatgaca
     7981 tttccagtga atacttcatg gtattctttt agcatcggac gcagataaac aatgaattct
     8041 tttactttct gtacaaaatc cggagcgata tcagcttgta ctcctccaat ggtgttatag
     8101 ttctgtatca gacgtcctcc ggtagttgct tcgaagatat ccagtatctt ttcacgatca
     8161 cggaatccat agaagaatgc ggtcaaggca cccatatcca tacagagaca ggagaagaaa
     8221 agcaagtgag agtctatacg ttgcaattcg tccataatgg tacggatgta ttgtacccgt
     8281 tcgcttactt ctacgcccat tgcctgttca atgcacatac aaagagcatg gcggttctgg
     8341 tgcgcaccta aataatccaa acggtcggtc agggccaagg tctggggata ggtaagactt
     8401 tcgcacatct tttcgatacc tcgatgtatg tatccgcagt gtacatccag tttcttgata
     8461 atttcgcctt ccagtgaaac gcgaaaacga agtacaccgt gggttgccgg atgttgagga
     8521 cctatgttaa tgatatattc gtcctcatca aaaatggttt ctcgtttttc tattacactg
     8581 ccatcatgtt gcacctctat atattgtgtt gtatctacag cctcctcatt ggtcatacgg
     8641 agtgggttga ggttttcatc gtagtcctta cgcaatggat agcctaccca gtcatcacgc
     8701 aggaacaaac ggcgcatatc aggatgtcct ataaagcgga taccataata gtcgtatact
     8761 tcgcgttcat tgaattcagc acctttccaa atatcactta cactaggaag ctccggtttt
     8821 tctcggttgg ttgtgcgagt gctgaccact atgttttctc ttgtcttcgt atcttccaga
     8881 tgatagacta cacctagtcc ttcttcgccc cagtccattc cggtaaggct gcgtagaaaa
     8941 tccatatgtt taccctgccg caatttcagc atttcttcat gtagcttttc ggcaggtatt
     9001 tctatttttt cactcatgct tgttcgggat tttgtggttc attttctttg cggttcactc
     9061 cgccaaagaa tttttccagt tttactttac gttgcaattg tatcatgccg tataacaagg
     9121 cttcaggccg tggcggacat ccgggaatat atacgtcaac gggaagaatt ttatctactc
     9181 cgttcaatac gtgatatgat tttttaaaag gaccgccgct aatggcgcat ccgcctaccg
     9241 caataacgta tttaggatcc gccatctggt catacaaacg ttttagtacc ggagccatct
     9301 tgtgtgtgat agttcctgct accatgatca tatctgcctg gcgcggactg gcacgggcta
     9361 cttcaaaccc gaagcgggcg aaatcatacc gggcagcccc cactgccata aactcaattc
     9421 cacgacaact ggttgcaaat gtaagcggcc acaacgaatt gctgcgtccc cagttgatga
     9481 ggtcgtccaa acagcccacc aatacttttg taccgctttc attgagctgc ttgaccatgt
     9541 tttccaaata ctcattgttt ttgaagtctt cataaggaat agactttatg gttggtttct
     9601 ttacttccat tccaacgctc ctttcttcca ggcatacgcc agacctaaaa ctaatataac
     9661 taaaaagaaa aggatgctaa acagaccgta cactcctagg tcttgtacca ctacagccca
     9721 agggaataaa aatactgttt ccacatcgaa catcaggaag aggatagcaa atagatagta
     9781 acctactttg aattgcatcc acgaccgtcc ccgtgtagga ataccacatt cgtaggcttc
     9841 tcccttttgt gagttgtatg aacggggaga aatggcacgg gcaatcccca atgctacggc
     9901 aactaatgcg attgccgtca agataacgac aactaataat gtaaaataca tatctaaact
     9961 ttttttgatt agacaaacgg atagaaaaat agtccttata agacgtttgt tataaggatt
    10021 tctactcagc gaaatgctga aaaaaaatta aaaattaaat gatgatccgc cggagtgcat
    10081 agatataata atctacggca tcagtgtaaa gcgaatgaaa ggtgtggcaa actatacggt
    10141 ttgtttgtag ctcttgcttt ttaagttcgc tcaatgctgt taaaatgcgg actatacatt
    10201 tgaactttga tgtggaaggg ttgtcaagtg atatggctat ttgtggcata tctgcaaaat
    10261 tgttggtaaa caggaaatcc actgttcttt tgcaagggtc ttgttgttgc tggtaacaag
    10321 atgtctgtgg gtgtagatct gtcggttcaa ccgtataatg atcctgatct actgttatcg
    10381 taaacagtag aaataatagg atatatac
//
