LOCUS       c00080_gnlPro..         9190 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMBODDLG_80.
ACCESSION   c00080_gnlPro..
VERSION     c00080_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:20:26
            Original ID  :: gnl|Prokka|BMBODDLG_80
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9190
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9190
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2904:8892]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2905..8892
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..9190
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9190
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..362
                     /locus_tag="ctg80_1"
                     /transl_table=11
                     /translation="IALAADSMDFYSSHLLELQRLRKIKKARARFIQLVWNNSPEEMEA
                     LGDSRENWNRGMNSDLRGKQEGGYYHGVSHGASQLNLIDYYYPDTKMIYLKKREEMHNQ
                     QQKSTHVKKNLSMNK"
     CDS             384..1598
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg80_2"
                     /sec_met_domain="OAD_beta (E-value: 6.9e-113, bitscore:
                     366.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENIDFGILFQGIGTMIESGWFLACARVFLILLGFLLIYLGWKGI
                     LEPMVMIPMGLGMIAINCGTLIMPDGNLGNLFLDPMLSDTDELMNTMQIDFLQPVYTLT
                     FSNGLIACFVFMGIGTLLDVGFLLQKPFASLFLALCGELGTFLTLPIANALGLSAQESA
                     SVAMVGGADGPMVLFTSLALAKHLFVPITVVAYLYLGLTYGGYPYLVKLLIPKRFRSIK
                     MTVKKAPKNYDAKVKLAFAAVLCAVLCFLFPVASPLFFSLFLGVAVRESGMKHIYDFVS
                     GPLLYGSTFMLGLLLGVLCDAHLLLDPKILKLLILGMLALLLSGIGGILGGYIMYYIKK
                     GNYNPVIGIAAVSCVPTTAKVAQKIVSKDNPDSFILGDALGANISGVITSAIITGIYIT
                     IIPLL"
     CDS             complement(1692..2777)
                     /locus_tag="ctg80_3"
                     /transl_table=11
                     /translation="MNNRLSLLLIGCIFPFLSFYAQKNMNLPPYYPTVKGITDYAVWQL
                     VYPDSLLRANIAGEAVCTLRIDSLGTVRCKYIEATHPLFAKAAEDVIEGMREWQPAKKA
                     GRDIDTTIVFHIPFNPDVYSDRIWRQQQVLESCRGQLVDSMPVFPDDIRSLVMGNMSWP
                     DDKVDKAVAICRFTVNEKGEIVDIRVIKGTHSAFDKESIRILSNFPRLIPAMKNRKSVP
                     YDYFLTMRFWKEDLEHYLLYRECAQEDLEKITWEPYRYSSYPGGTVALTQFINSHLKIT
                     PEMKATGKQGRVIYSFNVDIDGSMKDFQLVRGLDPLMDAEALRVLQLVNERWSTGYYFN
                     SKKWYREFYVNQFTIPIIFSW"
     CDS             complement(2905..3948)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_4"
                     /sec_met_domain="IlvN (E-value: 9e-47, bitscore: 148.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1e-41, bitscore: 131.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVTETVVIRDEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKATIVMCLLSDAAVMS
                     VWPTIKPYLTQGKALYFSHGFAITWSDRTGVVPPTDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDVTGKAYERTIALGIGIGSGYLFETTFQREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHSPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVEKLYHSVKTGNEAQISIDSNSKPDYREKLEEELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(3983..4726)
                     /locus_tag="ctg80_5"
                     /transl_table=11
                     /translation="MMSENKVGTYRFVAEPFHCDFSGKLTMSVLGNHLLNCAGFHAADR
                     GFGIATLNENHYTWVLSRLAVELENMPCQYEGFSIQTWVENVYRLFTDRNFAILDKEGK
                     TVGYARSVWAMISMETRKPADLLTLHGGSIIDYVCDKKCPISKPGRIKVTEKAPVSEYQ
                     TRYSDIDINGHVNSIKYIEHILDLFPIEFFKEKRIKRFEMAYVAESYYGDILSFYREEV
                     EEKEYDIEVKKNGTDVVVRSKVIFI"
     CDS             complement(4726..5280)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_6"
                     /sec_met_domain="ALS_ss_C (E-value: 1.1e-19, bitscore:
                     59.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTLYTLIVHSENIAGLLNQITAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTTQDVIEKVVKQIEKKIDVLQAHYFTDSEIYQHEIALYKVSTPEFQENPM
                     ASKVIRRYSARIVEVNPVFSIVEKNGMSEEITALYEELRGLGCVLQFVRSGRVAITTSC
                     FERVNEYLTQREEKYRQQKTE"
     CDS             complement(5291..6988)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-49, bitscore:
                     156.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKEKITGAEAMMRSLEYQGVKTLFGYPGGSIMPTFDALYHHRNT
                     LNHILVRHEQGAAHAAQGFARVSGEVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGASFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAVARAFYIAKSGRPGPVVLD
                     FAKNAQVEMVDYEPMKLDFIRSYDPEPNPDKESLQEAAELINNAQRPLVLVGQGVELGN
                     AQDELRAFIEKADMPCGCTLLGLSAIPTSHPLNKGMLGMHGNLGPNVKTNECDVLIAVG
                     MRFDDRVTGKLDTYAKQAKVIHLDIDHSEIDKNVKVDVPVLGNCKYTLAMLTQLIRKNE
                     HSEWIDSFTEYEKTEYEHVISKEIHPVDGALNMGEVVRAVSEASNNEAVLVTDVGQNQM
                     MAARYFKYSKNRSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIILLNNNYLGNVRQWQAMFFGHRYSFTPMLNPDYMKIAEAYEIPARRVM
                     KREELQAAIHEMLTTDGPFLLEACVIEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(7090..7191)
                     /locus_tag="ctg80_8"
                     /transl_table=11
                     /translation="MTPVTRDRKVPKSLKAYASMVSSADKGGVRIID"
     CDS             complement(7207..8892)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg80_9"
                     /sec_met_domain="ILVD_EDD (E-value: 1.7e-209, bitscore:
                     685.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNQLRSSFSTQGRRMAGARALWVANGMKKEMMGKPIIAIVNSFT
                     QFVPGHTHLHEIGQQVKVEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGEWNNQHLDLID
                     AMIKSADASVSDEDVAQIENNACPGCGCCSGMFTANSMNCLNEAIGLGLPGNGTILATH
                     ANRTQLFKDAAALIVKNAYKYYEEGDDSVLPRNIATRDAFLNAMTLDIAMGGSTNTVLH
                     LLAIAHEAEVDFKMDDIDMLSRHVPCLCKVAPNTQKYHIQDVNRAGGILNILGELSKGG
                     LLKTDVKRVDGLTLAEAVEKYNICKKEVDTEAKRIYSSAPGNKFNIKLGSQNAVYKELD
                     TDRANGCIRDLQHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPNRSINVKLSDE"
ORIGIN
        1 gaatagcgct ggcagcagat tctatggatt tctatagctc ccacctattg gaacttcaac
       61 gtttaagaaa aatcaaaaaa gcacgtgccc gttttatcca attagtatgg aataattctc
      121 cagaagagat ggaagctcta ggagacagcc gtgaaaactg gaaccgagga atgaacagcg
      181 atctgagagg aaaacaggaa ggtggttact accatggtgt cagtcatgga gcatcccaat
      241 taaatctgat agattattac tatccggaca caaagatgat ctaccttaag aaacgggagg
      301 aaatgcataa tcagcaacaa aaaagcactc atgtgaaaaa gaatctttca atgaataaat
      361 aacctgaaaa tcaacaatta gatatggaaa atatagattt tggaatactt ttccaaggca
      421 ttggtacaat gatagaaagc ggttggttcc ttgcctgtgc gcgcgttttt ttaattcttt
      481 tgggatttct actcatttat ctaggttgga aaggaatatt ggaacccatg gtcatgattc
      541 caatgggact cggtatgata gccatcaatt gtggaacatt aatcatgccg gatggaaatc
      601 taggcaatct ttttcttgat cccatgctct cggatacaga cgaattgatg aataccatgc
      661 aaatagattt tctgcaaccg gtttacaccc tcacattcag taatggactc atcgcttgtt
      721 tcgtcttcat gggaatcgga accttgctag atgtaggttt cctgctacaa aaaccttttg
      781 ctagtttgtt tctggcactt tgcggagaac taggaacctt tctcacattg ccaattgcca
      841 atgcacttgg cttatcggca caagagagtg cttctgtagc catggtagga ggtgcagatg
      901 gtccgatggt actgttcact tcattggcat tagccaagca tttgtttgta ccgattactg
      961 tggtagctta tctctattta ggattgactt acggcggtta tccctatttg gttaaattac
     1021 tgattcccaa acgtttccgt tccatcaaaa tgaccgtaaa gaaagcgccg aagaattacg
     1081 atgccaaggt aaagcttgct ttcgcagcgg tactctgcgc tgtactctgc ttcctttttc
     1141 cagtggcctc tcccctgttt ttctctctat ttctaggagt ggctgtacgt gaatcaggga
     1201 tgaaacatat ttatgatttt gtcagcggtc cattgcttta cggttctact tttatgctgg
     1261 gattattatt aggagtgctt tgcgacgctc atctgctact agatcctaaa atcttaaaat
     1321 tgctgatact aggtatgttg gcattgttac tatcaggtat cggaggtatt ttaggcggat
     1381 atatcatgta ctatatcaag aaaggaaatt ataatccagt cattggcatt gctgctgtaa
     1441 gctgcgtacc aactactgcc aaagtggcac aaaagattgt cagtaaagac aatcctgatt
     1501 catttatcct aggagatgca ctaggagcca atatatcggg agttattact tcagcaatta
     1561 ttacaggtat ttatatcaca atcatcccgc tattatgaaa cagcatgaat cctacctaat
     1621 aaatttcatc cacttttaat aatgctatca ttttcgcaga gggcagtccg cgtatctgcc
     1681 ctctgccacc actaccaact aaaaataatt ggaatggtga attgattcac ataaaactcc
     1741 cgataccatt tctttgaatt gaaataatac cccgtactcc atctttcatt cactaattga
     1801 agtacccgca atgcttcggc atccattaat ggatcaagtc ctctcaccaa ctgaaaatct
     1861 ttcattgaac catctatatc cacattgaaa ctataaatca cccgtccctg ctttcccgta
     1921 gccttcattt cgggagtaat tttcagatga gaattaataa attgcgtcaa agcaacagta
     1981 ccaccgggat aagaagagta tctataaggc tcccaagtga tcttttccaa atcttcctgt
     2041 gcgcattccc tatataataa ataatgctcc agatcctctt tccaaaaacg catagttaaa
     2101 aaataatcat atggcacaga ttttctgttt ttcatagcag gaatcaaccg gggaaaatta
     2161 gaaagaatac gtatggactc tttatcaaaa gccgaatgag taccttttat cacacggata
     2221 tccacaattt ctcctttttc atttaccgta aaacggcaaa tagcgacggc tttatccact
     2281 ttatcgtcag gccaactcat atttcccata acaagactac gaatatcatc aggaaagaca
     2341 ggcatggaat cgacaagttg tcctctgcaa gattccagaa cttgctgctg ccgccaaatg
     2401 cggtcactgt aaacatcagg attaaaagga atatgaaaga cgatagtagt atctatatct
     2461 ctacccgctt tctttgcagg ctgccattca cgcataccct caatcacatc ttcggccgcc
     2521 ttagcaaaca aggggtgagt ggcttcaata tatttacaac ggacagtccc caaactatca
     2581 atgcggagcg tacacacagc ttcacctgca atattggccc ttaataaaga atccggatat
     2641 acgagctgcc acacagcata atccgtaata ccttttactg taggataata tggcgggaga
     2701 ttcatgttct tttgtgcata aaaagataga aagggaaata tgcaccctat taataaaagt
     2761 gataatctat tattcatgcc taagtcaagt tttcacaaaa ttagcgacta cacatgatat
     2821 aaacaacacc actaacatta atatatataa aagaaagcgg agatacctca tcgcatcccc
     2881 gctttctaca ttaaatacta actattaatt attttcagga cgaagtttac gtacggttac
     2941 agcagtctgc cacatttcgc tttcacgcaa tgccttcaat tcttcttcca atttttcacg
     3001 ataatcgggt ttagagttag aatcgataga aatctgagcc tcgttgccag tcttcacact
     3061 gtgatataac ttttcaacta cgggtttgat agcatcgtga aatggggtca tccaatccaa
     3121 tgcaccgcgc tgagcagtgg tagagcagtt agcatacatc cagtccatac cattcttagc
     3181 aaacaaaggc atcaatgact gggttaattc ttctacagtt tcattaaatg cttcagaagg
     3241 actatgtccg ttttcacgca atacttcata ctgagccaac aacaatcctt ggatagcccc
     3301 cattaaagaa ccgcgttcac ctgtcaggtc agaagttgct tcacgctgga aagtcgtttc
     3361 gaataaatag cctgaaccga taccaatacc caatgcaata gtacgttcat aagccttacc
     3421 ggttacatcc tgatagatag cgtatgaaga gttcaagcca cgaccttcca agaacatggt
     3481 acgcagtgaa gtacccgaac ctttaggagc taccatgatc acatcaatat cagtaggagg
     3541 aactacccct gtacggtcac tccaagtaat ggcaaagcca tgagagaaat aaagtgcctt
     3601 gccttgggtc aagtaaggtt tgatagtcgg ccatacagac ataacagctg catcagataa
     3661 cagacacatt acgatagtcg ctttctgaca agcctcttca ataccaaaca gagtttcacc
     3721 cggaacccat ccgtcagcaa ctgctttttc atatgttttt cccggacgct gaccaacaat
     3781 tacattgaaa ccattgtccc ggagattcaa agactgcccc ggtccctgta caccataccc
     3841 gatcacagcg attgtttcat ctttcaatac ttcacgtgct ttttccaaag gaaattcatc
     3901 gcggataact acagtttctg taacgccgcc aaaattcaat tgtgccattt taaattataa
     3961 attaaaaatt aaaaattaga ttctaaataa atatcacctt actacgaacg acaacatctg
     4021 tgccattctt cttcacctct atatcatatt ctttctcctc cacttcctcg cggtagaaac
     4081 tcaatatatc accataataa ctctcagcta cataagccat ctcaaaacgt ttaatccgtt
     4141 tctctttaaa aaactctata ggaaacaaat cgagaatatg ttctatatac ttaatactgt
     4201 tcacatgacc attaatatca atatcgctat atctggtctg gtattcagaa accggagctt
     4261 tctctgtcac cttaatacga ccgggcttgc ttataggaca tttcttatcg catacataat
     4321 caatgatact acctccgtga agcgtaagca ggtcagcagg tttgcgagtt tccatactga
     4381 tcatcgccca tacagaacgg gcgtatccga cagtctttcc ttccttgtcc aaaattgcaa
     4441 aattacggtc tgtaaaaaga cgataaacat tctctaccca tgtctgaata ctgaaaccct
     4501 catattgaca gggcatattc tctaactcta cagctaaacg ggaaagtacc catgtataat
     4561 gattctcatt gagcgtagca attccgaaac cccggtcggc agcatgaaag ccggcacaat
     4621 tcagtaaatg attacccaac acactcatgg tcaactttcc actgaaatca cagtgaaagg
     4681 gttctgccac aaatctgtat gttcctactt tattctcact catcattatt ctgttttttg
     4741 ctggcgatac ttttcctcgc gttgggtcag atattcgttc acacgctcga aacagctggt
     4801 agtaatggcc acacgtcccg aacggacaaa ctgcaacaca catcccaatc cgcgcaactc
     4861 ctcataaaga gcagtaattt cctcactcat cccattcttt tcaacaatag agaaaaccgg
     4921 attcacttct acaatgcggg cactataacg gcggataact ttagatgcca taggattctc
     4981 ctgaaattca ggagtagaaa ccttgtacaa agcaatctca tgctgataaa tctcactatc
     5041 agtaaaataa tgtgcctgca aaacatctat tttcttttca atctgcttca ccactttttc
     5101 tatcacatcc tgggtggtcc aagcagtaat agtatattta tgcaccccct tgatggaaga
     5161 tgcagaaaca ttaagacttt cgatattaat ttggcggcga gtaaacactg ccgtaatctg
     5221 gttcagcaaa ccggcgatat tttctgaatg aacgattaat gtatataatg tcttgtccat
     5281 aattattaaa ttagcattcc agtaacatct gattcaccga gcctcccgga ggtgtcatcg
     5341 gcaacacatt tccctcttct atcacacaag cttccagcag gaatggcccg tcagtagtca
     5401 acatttcatg gatagcagcc tgcaattcct cacgcttcat aacacggcgg gcaggaatct
     5461 catatgcctc ggcaatcttc atataatccg gattcaacat cggagtaaat gaataacgat
     5521 gaccaaaaaa catagcttgc cattgacgaa cattacccaa atagttattg ttcaataaaa
     5581 taatctttac cggtgctttt tgctccatga tagttcccaa ttcttgaata ttcatctgca
     5641 aaccgccatc ccccataaat acgcatacag tacgatccgg gcgaccgaaa gtagcgccta
     5701 tagcagcggg aagaccgaat cccatcgttc ccaatccacc cgaagttaca atgctacggt
     5761 tcttactgta tttaaaataa cgagcagcca tcatttggtt ctgtcctaca tctgtcacca
     5821 atacagcctc gttgttcgaa gcctcactta ccgcacgcac cacttcaccc atattcaacg
     5881 ccccgtcaac aggatgaatt tctttactga taacatgttc atattccgtc ttttcatatt
     5941 cagtaaagct atcaatccat tcggaatgtt cattcttccg gataagttgc gtcagcatag
     6001 ctagcgtata tttacaatta cctaatacgg gtacatccac ttttacattc ttatctattt
     6061 cagaatggtc aatatccaaa tgaatcacct ttgcctgttt agcatatgta tctaattttc
     6121 cagttacacg atcgtcaaag cgcataccta cagcaatcaa cacatcacat tcattagttt
     6181 tgacattggg ccccagattt ccatgcatac ctaacattcc tttgtttaaa ggatgcgaag
     6241 ttggtatagc cgaaagtccc agcaaagtac agccacaagg catatcggct ttttctataa
     6301 atgcacgtaa ctcatcttgc gcattaccta actctacccc ctgtcctacc aacactaatg
     6361 gcctttgagc attgtttatc aattcggcag cctcctgaag agattcctta tcaggattag
     6421 gttctggatc ataactacgg ataaaatcaa gcttcatcgg ttcataatcc accatctcca
     6481 cttgtgcatt cttggcaaag tccaaaacga caggaccggg acgtccgctt ttagctatat
     6541 agaaagcacg ggctacagcc caagctacat cttccgcacg acgaatttgg taactccatt
     6601 tggtaatagg ctgagtgatg cccaccagat ccacttcctg aaaagcatcc gtacctaaaa
     6661 aggaagctcc tacctgcccg gcaatcacca cgataggcgt gctgtcaatc atagcatcgg
     6721 caatgccagt aatggtattt gtcgcaccgg gcccgctagt caccaaacag acaccaacct
     6781 caccggatac gcgggcaaat ccctgtgctg catgggcagc tccttgttca tgacggacca
     6841 atatatggtt caatgtattt ctatgatgat ataaagcatc aaaagtaggc atgatagaac
     6901 ctccgggata tccgaaaaga gttttcactc cttgatactc caaagaacgc atcatcgcct
     6961 ctgctcctgt tatcttttct tttgccataa ttgtttagtt gagaattgag aatcaaaaaa
     7021 atacgatgcc gtacaatcga ccaatcacaa caaatctatt ttttttattc tcaattttta
     7081 atttctaatt tagtcaatga ttctcactcc tcctttatct gcagaactta ccatactagc
     7141 gtatgccttc aagcttttag gaactttacg gtcacgggtc accggtgtca tcggtcgggc
     7201 ggccaattat tcgtcactca gtttcacatt gatactgcga ttcggaatat cgatttcaat
     7261 tatatcacca tccactattt ttccgatatt accacccgct gcagcttcgg gagaaatatg
     7321 cccgatgctt aatcccgaag ttcctccact aaaacgtccg tcggtaatca aagcacattc
     7381 ttttcctaaa tgcttggatt tgatataaga agtaggataa agcatttcct gcataccggg
     7441 accacctttc ggaccttcat gagtgataac aacaacatct ccgctgacta cttttcctcc
     7501 taaaatacct tcacaagcag catcctgcga atcaaacacc ttggcaggcc ccgagaattt
     7561 ccaaatactt tcatccactc cggccgtttt cactacgcaa ccatcctgtg caatgttccc
     7621 tttcaaaacg gccaaacccc catctttact ataggcatgt tgcaaatcgc ggatacaacc
     7681 attggcacga tctgtatcca gttctttata aacagcattc tgagaaccta actttatatt
     7741 gaatttgttt cccggagcac ttgaataaat acgttttgct tcagtatcca cttctttctt
     7801 acatatatta tatttttcga cagcttccgc caatgtcagg ccgtccactc gtttcacgtc
     7861 agttttcagc aaaccaccct tggataattc tcccaatata ttaaggatac caccggcacg
     7921 gttcacatcc tggatatgat atttctgtgt attcggagct actttacaca aacaaggcac
     7981 atggcgtgaa agcatatcaa tatcatccat cttgaaatct acttccgcct cgtgggcgat
     8041 agctaaaaga tggagcacag tattggtaga accacccatt gcaatatcca atgtcatggc
     8101 attcagaaaa gcgtcacgag tagcaatgtt gcgtggtaac acgctgtcat ctccctcctc
     8161 ataatattta taagcattct tcactatcag agcagccgca tctttaaaca actgagtacg
     8221 gttggcatga gtcgccaaaa tagtgccatt ccccggaagc cccagaccaa tagcctcatt
     8281 gaggcaattc atggaattag ccgtaaacat acccgaacag caaccacagc caggacacgc
     8341 attattttca atttgagcca catcctcatc gctgaccgat gcatcagcag atttaatcat
     8401 ggcgtctatc aaatcaagat gctggttatt ccattctccc gcttccatag gaccacccga
     8461 tacaaaaaca gccggtatgt tcagtcgcat ggcagccatc agcatacctg gagtgatttt
     8521 gtcacaatta ctgatacaca ccattgcatc cgccttgtga gcattcacca tatattccac
     8581 gctgtcggca atgatatcac gactgggcag tgaatacagc ataccatcgt gtcccatagc
     8641 tattccgtca tcaatggcaa tcgtattgaa ttctgctgca aaacatccca gtttttcaat
     8701 ctcaactttc acctgctgac ctatttcatg cagatgggta tgtcccggaa caaactgtgt
     8761 aaacgaattt actatggcta taatgggctt gcccatcatt tcttttttca tgccgttagc
     8821 cacccataaa gctctcgctc ctgccatacg gcgaccctgt gtgctaaacg aactgcgtaa
     8881 ctgattcttc atcttattct aaatctataa cgtcctatac ttattgaaaa agccttcctc
     8941 accatgtgag aaaggcttcc aattatttct ttatatgtac aactacacat acacaacctt
     9001 tctcacgctc ctagtgtgac caccacgacg cgaataatat gcaggactgc taggttattt
     9061 agagtagtaa tattcatata tctgttttct ttgtttcttt aacgactgca aaggtaaggc
     9121 gtttttagta acaaacaaat aaaatgaaga ttttttttct tataaattat tattcgtaac
     9181 taaatcgagc
//
