LOCUS       gnlProkkaJNBBPICE_178  15314 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNBBPICE_178.
ACCESSION   gnlProkkaJNBBPICE_178
VERSION     gnlProkkaJNBBPICE_178
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:48:03
            Original ID  :: gnl|Prokka|JNBBPICE_178
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6696
            Orig. end    :: 22010
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15314
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10267]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15314
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15314
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(3714..4604)
                     /locus_tag="ctg178_8"
                     /transl_table=11
                     /translation="MIVQPTVKHVGTYRWFVVVMYGQAFVIHAVIGFLPLLSKKIDGFT
                     PHTELLLGYLWHTGNGNQAHLDMPIGNHHGIGLIGQVVGTEIITAHITQQGTDTGTLPI
                     QISHIELFSRTDKGTSASQLHNASGTLAETTIIYRIYKVGVTHVHRILQLCLQRVLRVD
                     KCLVADASVEIAIIAQQVNRRLLAYIGIHRRHKHRSGGKFIEYPLSESLLILLETIVNP
                     QSERKGIADSRASQQRIVRCRSKGGFHLFHSNLTNRRFTAVQYNHRLLAGIEYLPLGQV
                     LRGGATCQKYQSCNI"
     CDS             complement(5097..5519)
                     /locus_tag="ctg178_9"
                     /transl_table=11
                     /translation="MVPEFRVQLQELCKRYPEKLLSFLTERLAENTVDGRSQVTGRRNG
                     GLPPDGVTLAAHGSVVISIGVLHGRNELVAQTNVECRILGTQRIESGSRIAQYIECQPE
                     RSYTVPGSRFGLEVISDITAKSQQLIILGTVHLVGI"
     CDS             5640..6053
                     /locus_tag="ctg178_10"
                     /transl_table=11
                     /translation="MRAFSARSIGPGGYPPETDRKYTYINHVGDIRIEANIEYRFRMIA
                     DLHGAVFLDAGNVWLMRKDENRPDGEFTLKNFPKQIALGTGFGLRYDLDFLVFRLDLGI
                     GLHDPYDTGKSGYYNIPKFKDSMALHFAIGYPF"
     CDS             6180..7091
                     /locus_tag="ctg178_11"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDANNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(7136..8806)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 275.5; E-value:
                     1.5e-83)"
                     /gene_kind="transport"
                     /locus_tag="ctg178_12"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHVAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTAAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLLGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVLDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFGYTPDDRPVFSRFSCRFPAGSCIAVVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETSHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASEEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(8829..9884)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg178_13"
                     /sec_met_domain="NTP_transf_5 (E-value: 9.1e-42, bitscore:
                     134.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANSQALLALTFDGISSLPAELRPPRALYLKWAARTAQIEQANKR
                     LNQLLPELNTLYREAGLYPVLLKGQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLL
                     QQGAIVEGEASDKHASYSLKGVHIENHRIILRLNSPLANRHFQQIIRKWYPQETDYALF
                     SETGKEDSKAVSIAIPPATFNALYIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDA
                     TTLLRQLQDLGLLHAAQAFGYIAVTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFG
                     QHDNRIKPRPKGYWAGKWYTFCRATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRLK
                     GVKDKKARTKK"
     CDS             complement(10001..10267)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg178_14"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.1e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.7e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             complement(10280..10624)
                     /locus_tag="ctg178_15"
                     /transl_table=11
                     /translation="MNPFLVDRRDRVTLGDFTTEQLQPGVAVLARDLTERIVFHRIIRR
                     NGNILILQGDGNLAQTEETDIGRVMGVMTEAMRKDKRYTADGKVWKLYSYWWMKLNPAR
                     RWLLALFRRI"
     CDS             complement(10747..11259)
                     /locus_tag="ctg178_16"
                     /transl_table=11
                     /translation="MMLYAFNAARHHTLLMHASVVATETGKGYLFLGKSGTGKSTHTGL
                     WLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTPCYRKESMTVGAFVRLEQAPQ
                     NEIEQERAAHAFATLLPSCSCLKQNKGIYNAIVTTVTELATLAPVYHLKCLPDREATEL
                     CRKTVEG"
     CDS             11727..11849
                     /locus_tag="ctg178_17"
                     /transl_table=11
                     /translation="MNVCVNEEDLRDFSTVLLSFFRRGGRRFIKENPLSAASKR"
     CDS             11878..12135
                     /locus_tag="ctg178_18"
                     /transl_table=11
                     /translation="MVCEDILLPFLEFGLSVLLTCWANNIFFPPIVDFVGCCIYTAVTG
                     NLVTCYQIGFIVVHIRICRVEIDERSTGHLDAGSVLVCIL"
     CDS             complement(12446..12820)
                     /locus_tag="ctg178_19"
                     /transl_table=11
                     /translation="MPKQSHSSQKAPLIHRSSTLPAVHSPTQAXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXYILRPKRTEVHGNQRNCGYKTSLKYQHRQDGACHRLHIECC
                     KRNGKLKPEWPRHHQFLRNS"
     CDS             12838..13011
                     /locus_tag="ctg178_20"
                     /transl_table=11
                     /translation="MFTVAMPYAPLTLMAAQSSPPVPSPQLPVLPVPLLVIKAVPSTFR
                     VPRWMHTPPAAP"
     CDS             12981..13556
                     /locus_tag="ctg178_21"
                     /transl_table=11
                     /translation="MDAYTSCGTINLAATDGRCAGLGQIDCIVSSRNEFSVCDVDDGVL
                     RLVIAVACHCKPSGFYLAACHGEVSTVRHSDAILAVTVRSLSDCTDVAAFHGHGGIFTG
                     YFNQTAIIRSRCIILAGNYLAFLLGRAVLQCHLAQDDDFACCAVVGSQCISVQVKNHGL
                     SGGYTDALPCDVGIGGQFKIFAVGESGL"
     CDS             13665..13952
                     /locus_tag="ctg178_22"
                     /transl_table=11
                     /translation="MFYLSIYLQVTAFYGQLLYGDACIDNQCLLGGSGSHFIVSGFIAY
                     CCQCNGGAWHGDGYRRSFLLCCGFRHSQGYTVGGSGGGSTYAGIGLVGQL"
     CDS             13894..14295
                     /locus_tag="ctg178_23"
                     /transl_table=11
                     /translation="MVAVAAGVLTLVLVLSVSFNGAEVLVVGAVLNARLMSEFCKTGMA
                     MPSLLPEVVLKLPLTAMSVTVAAVGASCGRFFESAKAVLSALGVVASTTTQSKGGTTNM
                     SLLPRILSLSVLVKYTLSLPFVSWAVMEL"
     CDS             14323..14598
                     /locus_tag="ctg178_24"
                     /transl_table=11
                     /translation="MRDFISAEAVKEAVISLLSSLVTASIGSAAVKSTVQVPAMLLEAI
                     ILKVVASAGILLTVSFIMAAMCLKDRALRLSGFVTLAYIGPLLLPL"
     CDS             complement(15016..15231)
                     /locus_tag="ctg178_25"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             complement(15245..15313)
                     /locus_tag="ctg178_26"
                     /transl_table=11
                     /translation="MIKYNHCCFSIYSFHVFLLFNL"
ORIGIN
        1 ccatgtatga gcgttccggt ttgagtgtaa cttccctgac cgggcggttg tttgccgatt
       61 ctaccgttat ccgtatccct tctttgaagt tgctgacacc tcatagtgag atgaacctta
      121 cggcacagac ttactgggaa ctgataaata tacctaccac cggccgtctg acagcccgtt
      181 tcaatgcccg tatcggcaaa caggatgtac tgctttttgc cggtggcttg ccggaagctt
      241 tcaaggaagc ctatccgttc cgtccgttgg tgattcatgc cggtacggaa ggaaacctga
      301 agcagatgca gatttcccgt tttacggctg agctgcccgg agccttttcg ttgagtgggg
      361 gaggagaatt ctggagcttg accgacagtg tgaaacgtaa tggaagcatg gacttcgaaa
      421 tgcatacgca gaacttgaac ttcctgaccg gactagctga cattgctccc gatggctcca
      481 tcattgtgcc ggacagtatg caccttgcgg cacgtctcgg tatggagggg gcgcagtgca
      541 ctgccgccct gaaactgaag gagaaggaag gcgccttgaa tttggacgcc gcctataatc
      601 ttgctacgga agcctaccat gccgaccttg ccatcaacaa cttgcaggtg catcacttcc
      661 tgcccaagga ctctatctat actcttacgg caaagatgtc cgctaagggg caaggggtgg
      721 atgtggtatc acgaaaaact gtggccgctt tgaatgcctc cttggaaaaa ctacagtatg
      781 gccattggga catttccggt gtagatgtgc atgccggact caagtcatcc gttgctaccg
      841 tccgtcttgc cagcgataat gtccttctca agatgcaggg aaatgcggat atgcgtcttg
      901 accgcaacta tctggatggc gctttggatt taaatgtgga agaggtgaat ctgcataagc
      961 tgggtttggt gccccgacca ttgcaacacc cgtttgcctt tacaatggga gcggaggcac
     1021 gtcatgattc tctcaagttg aggcttgatg ccggtgactt gaatctgcgt ttccgcgctc
     1081 acagcacgtt gaagaagttg atggaacagt cggataaatt tgtctctatc ctgacaaagc
     1141 agattgatga acggcgtttg gaccatgccg ctttgcgcca agtccttcct tcagcgggca
     1201 tgcatctgga agccggtaac cagaatcccg tcagctattt cctggctgca aagggtattt
     1261 cctataatga tttcaaactg agcttcggat ttactccgca agtcggcatc aatggacgta
     1321 cagctgttca cggattgcgc atggactcct tgcagctcga tacgatattt tttacagtga
     1381 agcaggatac tgcccgcatg aagttgcaag gtggtgtcat aaacggtccc aagaacccgc
     1441 agtttgtgtt ccgtagcaca ctgacgggtg aagtccgtaa tgaagatgcg gaactgactg
     1501 tggattatgt gaatggaaaa gggcagaccg gtgttctatt cggtattaat gcccgtccgt
     1561 tgaccgaagg acacggtcgc ggtaatggtg tgctgctgaa ccttattcct gccgagccga
     1621 ttatcgcttt ccgtaaattc cactttgcgg acaatagtaa ctggatttat ctgcataaga
     1681 atatgcgcgt ctatgccaat attgatatgg acagcgacga tggtctgtgt ttccgtatgc
     1741 aatccgacaa gaatgatacc ctttccttgc agaatataaa cgtagaactg agccgattgc
     1801 gcttggatga acttacggag gtacttcctt atatgccccg gcttacggga ttgttctccg
     1861 ccgaagcaaa ttatatacag actgccactt ccctgcaggt gtccgccgaa gccaatgtag
     1921 agaaactgac ctacgaacgc caaccggttg gagacatcgg cctgggggct acctggttgc
     1981 cgggcgacaa gaatacgcac tatctgaata cctattttac atatgataat gaagaagtga
     2041 tgaccgccga cggtatcttg acgcagaaga acggaaagga taccctggaa gtgtccaccc
     2101 gtttcgagca ttttccattg aagatggcca atgcattcat ccctgaccaa acggtggcct
     2161 ttaccggaga tattgatgga gggctttata tttatggttc gctggacaag cctcaaatgc
     2221 atggtgatat tgttttggac agtgtgtctg tctatgcacg ccaggcggga gcacgttact
     2281 ggttcgacaa ccgtccggta cagataaagg acaatcagtt gatatttgat aagtttgcca
     2341 tttataccac cagcaagaat ccgtttacga ttgacggtaa ggttgatttc cggaatatgg
     2401 agcgtcctac tgccaacctc aatctgctgg cagagaacta tacgttgctg gatgcaccgc
     2461 gtactcgcga aagtctggtg tatggaaagg tgttcgtcga cttgcatgcc acggtgaagg
     2521 ggccgcttga cgggctcacg atgcgtggaa acatgaattt gctgggcaat accaacgtaa
     2581 cctacgtgtt gaccgattcc cctttaacgg tggaagaccg tctcagtggg ctggttacct
     2641 ttacctcgtt caccgatacg acgtcggtaa aagcagatga ggttcctgcc atgtctttgg
     2701 gaggattgga aatgtatatg tccgtccata ttgacgatgc tgtccgtctt cgtgccgact
     2761 tgagtcccga ccgtagcaaa tacatcgaac tggaaggtgg cggtgatttg aatatgcagt
     2821 atactcccca aggggatatg agccttaccg gacgctatac cctttcgggt ggcgtcatga
     2881 aatattcgct gcctatcatc ccgttgaagg agttccagtt caatcccggc agttatgtgg
     2941 attggcgggg gaatattatg aatcctacgc tgagcctgaa ggctacggaa cgtatgcgtg
     3001 cttctgtggc cgatggtgac ggggacggtt cgcgcatggt gaacttcgat gtttccattt
     3061 ccatcaagaa caggcttgac gctcccgatt tgatattcga tatttcggcg cccgaagatg
     3121 ccgcagtaga gaatgagctg caggcaatgg gtgcagaaga gcgtagcaag caggccattg
     3181 ccatgcttgc cacgggtatt tacctgaaca gtggtgccaa aggaggaggt ttgtcaatgg
     3241 gagccgcctt gaactcagta cttcagagcc agataaactc cttggcggga ggtataaaag
     3301 gggccaatat cagtgtaggt gtggaagacc gtacctctgc tgaaacgggt gacacgcaga
     3361 aagacttcag ttttcgttat tcccagcgtt tcttcaacga ccgcgtacag atagtcatcg
     3421 gtggaaaagt gtccaccggg gccaatgcca cgaacgatgc ggaatcattc attgacaata
     3481 tatcgctgga ataccgtctt gatgcgtcgg gtactcgata tgtccgtgta ttccataata
     3541 aaaactacga aagcatactc gacggtgaga taaccgaaac gggtgtcggc cttgtgctgc
     3601 gccggaagat ggaccgattg agtgaactct tcatcttcag gaagaaaaag ataaaaccgg
     3661 aggctgaaaa tagcgatatg aaaaagtagg aatgtgatat gaaacgactg atattatata
     3721 ttgcaggatt gatatttctg gcaggttgct ccaccacgaa gcacttgccc gagggggaga
     3781 tactctatac cggccaaaag ccgatgattg tattgaaccg cagtgaaacg tctgttggtg
     3841 agattgctat ggaagaggtg gaagccgccc ttgctacggc accgaacaat tcgttgctgg
     3901 gaagctctac tatccgctat ccctttcctt tcggactgtg gatttacaat ggtttccaga
     3961 agtatgagaa gggattcgga aagtggatat tcaataaatt tgccgccact ccggtgctta
     4021 tgtctacggt gaatcccgat atacgccaga aggcggcggt taacttgttg cgcgattatg
     4081 gctatttcaa cggaagcgtc agctacaaga catttatcga cccgaaggac tcgctgaagg
     4141 caaagttgca atatacggtg aacatgcgta acccctactt tatagatacg gtatattatc
     4201 gtggtttcag cgagcgtacc actcgcatta tggagctggg acgccgacgt tcccttatca
     4261 gttcgggaga acaattcaat gtggctgatt tggatgggga gcgtacccgt atcagtaccc
     4321 tgctgcgtaa tgtgggctgt tattatttcc gtcccgacta cctgacctat caggccgata
     4381 ccatgatggt tcccaatggg catgtccaga tgcgcttgat tcccgttccc ggtatgccaa
     4441 aggtagccga gaagcagttc cgtgtggggc gtaaatccgt ctatcttctt ggaaagcagg
     4501 ggcaggaacc caatgacagc atggattaca aaggcttgac catacattac tacaacaaac
     4561 caccggtacg tcccaacatg ctttaccgtt ggttgaacta tcaaggttat cgacggaaac
     4621 gtcagataca ggacagcgca ggtattgccc gccagcgttc tatgcagagt ttgtatagct
     4681 tataccgtca aacccgtatt caggagcgtc tggcaagcgt cggtattttc cgttatgcgg
     4741 agatacagta tataccgcgt gatacggcgt ttgtgtctga tacattggat gtgaaggtca
     4801 ttgccgcgct cgataaaccc tacgatgcgg aattggattt taatgtcacc atgaagagta
     4861 ataaccagac gggaccgggt gccgctttta cggtgacgaa gaacaatgtc ttcggtggcg
     4921 gtgaaagctg gaatgtgaag ttgaacggtt cgtacgaatg gcagacgggc aaggcaagtt
     4981 cttccttgat gaacagttat gaactgggta tctccacttc gcttatcttt ccgcgcgtgg
     5041 tgtttcctag gatgggcgac cgtgagtatg acttcccggc tacaacgact ttccgtttat
     5101 atgccgacca gatgaaccgt gccaagtatt ataagctgtt ggcttttggc ggtaatgtca
     5161 cttatgactt ccagcccaaa tcgacttcca ggcacagtat aactcctttc cggttgacat
     5221 tcaatgtact gcgcaatcct actgccgctt tcgatacgtt gcgtgccgag aatccggcac
     5281 tctacgttag tttgcgcgac cagttcattc ctgccatgga gtacacctat acttatgaca
     5341 acgcttccgt gcgcggcaag cgtaacccca tctggtggca gaccaccgtt gcgtcggccg
     5401 gtaacctgac ttctgccgtc taccgtattt tcggcaagcc gttcagtgag gaaggaaaga
     5461 agcttttcgg ggtacctttt gcacagttct tgaagctgaa ctcggaattc aggtaccatt
     5521 accggataga caagaaccag atgatagcct cgcgtattgc cggaggggtg atatggtcgt
     5581 atggcaacgc tacgaccgca ccttatacgg aacagttcta tatcggcggt gccaacagtg
     5641 tgcgcgcctt ttctgcacgc agtataggtc cgggcggcta tcctcccgag acggatagga
     5701 aatataccta tatcaaccac gtgggtgata ttcgcataga agccaatatc gagtatcgct
     5761 tccgtatgat tgccgacttg catggagcgg tattcttgga tgccggcaat gtatggctga
     5821 tgcgtaaaga tgaaaaccgc ccggatggtg aatttacgtt gaagaatttc ccgaaacaga
     5881 ttgctttagg cacgggattt ggcttgcgtt acgatttgga ctttcttgtt tttcgtctgg
     5941 acttgggtat cgggctgcat gatccgtatg ataccgggaa gtcggggtat tataatattc
     6001 ccaagttcaa ggacagcatg gcgttgcatt ttgccatcgg ttatccgttc taaatgtacc
     6061 tttttgaacg gatagtggta aagaatgaac taaaactccc ttctgtcagc cataaatttt
     6121 tgtacatttg caaccgttat caactgtgat acactaacct ttttaaataa taactaagta
     6181 tgaaaccaac tttattctta ttggcagccg gcatgggcag ccgttatggt ggcttgaaac
     6241 aattggacgg actgggcccg aatggcgaaa ctatcatgga ttattctatt tacgatgcca
     6301 tcaatgcagg ctttggcaag cttgtgtttg ttatccgtaa agattttgag caggatttcc
     6361 gcgacaagat tatttccaaa tacgaaggcc atattccgtg cgaactggta ttccagtcca
     6421 ttgatgacct tcccgaaggc ttcacttgcc ccgaaggccg taccaaacct tggggaacca
     6481 accatgctgt aatgatgggt gccgatgtaa taaaggaacc gtttgctgtt atcaactgcg
     6541 acgatttcta cggtcgtgac tccttccagg taatgggtaa atttcttgca gcccttcccg
     6601 aaggctccaa aaacgtatat tccatggtag gcttccgcat cggcaacacg ttgagcgaaa
     6661 gcggtaccgt atcccgtgga ttgtgcggaa cggatgcgaa caacctgctg acttccgtag
     6721 tggaacgcac caagattcag cgcatggacg gtgaggtgaa atacatcgat gataacggtg
     6781 aatggactgc cactcccgag acgactccgg tcagcatgaa cttctggggt ttcactcccg
     6841 attactttgc ttacagtgca gagtttttca agagtttctt gagcgacccg aagaacatgg
     6901 agaacctgaa gagcgaattc ttcatcccgc tgatggtgga taagctgatt aacgatggca
     6961 ctgctacctg cgaagtgctc gacacaacca gcaagtggtt cggtgtgact tatcccgaag
     7021 accgtcagag tgtagtcgac aagattcagg ctttggtgga tgcaggcgag tatcctgcaa
     7081 agctgttctg agtttgttaa ccaaaggcag atacccgttg gggctcattc tctgattata
     7141 atcggacaat agattcgcat gcctccgcta ctgccggatg gtgggtgacg aagatacatg
     7201 ttttgcctgc gcagtctctg cgcaggtttt ttattaacag ccgttccgtg tcggggtcga
     7261 gggcagaagt ggcttcatct aaaagaagaa tgtttccggg gcgtagcaga gcgcgggcaa
     7321 tggcgatgcg ttgggcttgt ccttcactga gtccgccacc tcgttcgctg agtggggagt
     7381 ctacgccgtc gggaaggtgg aagacgaagt cggcggtggc ggtttgcagg gcttgatata
     7441 tggcttcttc agaagcttgt gggtttccca tcagcaggtt gtcacggata gttccgctga
     7501 aaagggtatt gccttgcggg acatatacga agttcttgcg ggtttgcgga gagacggtat
     7561 gactggtttc aagtggatgt ttggcgggta tcaagagtat ctgtccctct tgtggcgttg
     7621 ccagtgccaa caatagccgg atgagcgttg tctttccttt tcctgtttct ccgactacag
     7681 ctatgcagct accggcgggg aaacggcagg agaagcggct gaataccgga cggtcatcgg
     7741 gagtgtagcc aaaagtcacg tctttcagtt ccagttccgg ggtagaggcg aggaatatgc
     7801 tgtcaccgtc cgcttctgcc ggcagtcttt ccaattccaa tagccggtct atggcggtaa
     7861 gggcattgac tacggaaggt atcaggcgtg agaggtcgag cacgggacgc tggacttttc
     7921 ctaccaattg caaaaaggcg gtcatcgttc cgaaggtgat acagcctgcg ctgaggtgaa
     7981 cggctcccca aagaaaagcc gtgaggtatc cgccggaaaa ggcaagggcc actaacatgt
     8041 gggcggaaag cgagaaacgg gtacgtccca tgacttggct gtggagcatg tcttgcaagt
     8101 catcgagttt gtccagatgc cgttcgcctt gttccaatgt tttaatcact atgcgatgtt
     8161 gcaggctctc ttgtatgacg gactggatgc gaccgtcact gttccgaata tcatgtgtat
     8221 agcgtttcat tcgtcgcata tagaaacggc tgcctaatag aaagacgggc aggatggcaa
     8281 caatcagcca tggcagtgaa gggtctaaaa agtagaagaa tagaaaggct gccagcagtt
     8341 gtatactcgt gacgatgaat gccgggacag aagaggtgag caatgtgacg atggcggcgg
     8401 tgtcttgttc tacccggttc actacgtctc cggtatggaa acgctccaat tcgttccagc
     8461 ggctttgcag taagcgcgag aagaggcggt ggcgaagggc gttgcccgtc tctatctgca
     8521 tacgggtact tatccaagtg tcagcagctc cgcacagtaa ttgggcagtc agcaggacaa
     8581 cggtgagaac ggcgacatgc gtcaggttgt cgtctgttat tccggtagcg gtgtctatca
     8641 cccgtttggt tgcatagata aaggctaggg caaaggccac gcccagaatg ccggtgaggc
     8701 aacttagcag gatacgtccg cgttgttcgg cagatacctc tcgaatatac ctaagttttt
     8761 cacgtctgtc ctttttcact tttttgtcct tctgttgctt tttcattcct tttattttcc
     8821 gggttctttt atttctttgt ccttgctttc ttgtctttta ctccttttaa tcggtttatt
     8881 tgtatagcta tcgttccccc tatcagagtc acgggatacc agagtgcttc gtacggtgca
     8941 aattgacgca gttcgttgca gcgtcgggtg gcgcggcaga aggtgtacca ctttcctgcc
     9001 caatatcctt tggggcgtgg cttgatgcgg ttatcatgtt gcccgaagtt accggtagac
     9061 aggatgtctt ccaataattg ttctcctatc tgcttggtgc cttccaaggg gaaaggaagc
     9121 cggttggcgg gcaatcccag tcgggtgacg gcaatgtagc cgaatgcttg tgcggcatgc
     9181 aatagtccga ggtcctgcaa ctggcgaagc agggtggtgg catctatttc tttgtggcga
     9241 ttggcaagca gacaagtcca gtcgcatagc tggcgcaggc cgattccgct gttcaggaaa
     9301 tgtacaaagg catgtaggaa gatataaagt gcattgaagg tggccggagg tatggcgata
     9361 ctgacggcct tcgagtcctc tttcccggtt tcggagaata gggcatagtc tgtttcctgc
     9421 ggataccatt ttctgataat ctgctgaaag tgccggttgg caagcggact gttcagccgg
     9481 aggatgatgc ggtggttctc gatgtgtact cctttcaaac tgtagctggc atgcttgtcg
     9541 gacgcttctc cctcgactat ggcgccttgt tgcagcagga ggcggttggc tatgggttgt
     9601 ccttgttttc ctaaatagat gtcgatgtct ccgcattgcc ggtgcaaggg agtgcggtag
     9661 ttggtgccga tgccttgccc tttcagcagt acgggataca gcccggcttc ccggtaaagg
     9721 gtattgagtt cgggcagaag ctggttgagg cgtttgttgg cttgttctat ctgtgcagtc
     9781 cgggcagccc atttcagata gagggcgcgt ggagggcgca gttcggccgg tagactgctt
     9841 atgccgtcaa aagtcagtgc aagcagggct tgtgagtttg ccatgcggta cacggtttcc
     9901 cagtcgtccg gcgagaccga ccggaagagt tgtcggtctg ccggagtgcc ccacaggccg
     9961 gagcgtacca atgaaaagaa agcgtgttgc atatccgtcc ttattctatg attccttcgc
    10021 ggtcaaggga gtcgataaac ttctgcgcat cgcgacgggc cgattcgtta tctacatcat
    10081 agcggctggt cagggcttct gtcacgctgt ctgtatcgaa ctctttgttt tctatctctt
    10141 gccaaagcat ggcggaagtt tggttcaggc tgatgacttt gctgaagtcc acgttcgacg
    10201 agccgtcttg catgatgatg tagtcatcgc ctatccggtg caggataaat ccttgtttga
    10261 ttttcatggt tattttgttt tatattcttc tgaacagggc gagcagccag cggcgagcag
    10321 ggtttagctt catccaccag taggagtaga gcttccagac tttgccgtcg gcggtgtacc
    10381 gtttgtcttt tcgcatggct tcggtcatga cgcccattac ccgtccgatg tcggtttctt
    10441 cggtctgggc gaggttgccg tcgccttgca ggatgagtat atttccgttc cgacggatga
    10501 tgcggtgaaa gacgatgcgt tccgtcaggt cgcgtgccag tacggcgacg cccggttgca
    10561 gctgttctgt ggtgaaatcg cccagtgtca cccggtcacg gcggtccact aagaaaggat
    10621 tcatgctgtt gccccgcacg gtgatggtta ctgtatgccc ctctttgatg agacgcgcca
    10681 cttcgggaag caatatctcg ttgggaatgc ttttcttcat cggctgttca gttcatcatt
    10741 cataacttat ccttctaccg tctttctgca aagctccgtc gcttcacggt cgggcaggca
    10801 tttcagatga tagacgggtg ccagcgtggc aagttccgtc acagtggtga caatggcgtt
    10861 atagattccc ttgttctgct tcaggcaaga gcaggagggg aggagggtgg cgaaagcatg
    10921 tgctgctctc tcttgctcta tttcattctg cggtgcttgt tccaagcgga cgaaggcgcc
    10981 tacggtcatg gattctttcc gatagcatgg tgtctttccg ctccacggag aaccgaaaac
    11041 agtggcttgc ttgccgaggc tgtccacatg tactatcgga ttgtcatcgt tcagtagatg
    11101 gcagtccgag aactgttgca gccagagccc ggtgtgcgta cttttgcccg tgccgctttt
    11161 ccctaagaag aggtagcctt tgcctgtttc agtagcgaca accgaggcat gcatcagcag
    11221 tgtatggtgg cgggcggcat tgaaggcata gagcatcatc aagaagttgt tcagtacgaa
    11281 gttcgtttcg ttttccggag ccggtgtttc tgtcctgcag gccggtaggt ggatgaagca
    11341 ttgcctgaag ttatcgttgc actccatcca atagtttttc ccgcttttcc gtggggtgat
    11401 ggatacaagg tgtgagctgt ggggcaaagg gcgaatgatg caatcggcat cttcccagtt
    11461 gaaacatata tcatcgggag ttttcgctat ggttcgtttt gtcgctgttt cgtcatcgtc
    11521 tatctctgtt tcaaagatta ctttttgcgt cgtgtctatt gtcgtgatga acggaatcag
    11581 tgaaggcaac gccttgaata tattgaagtc ggaaggtttc accatgcgga aggtgtgcgg
    11641 tcctacttga taatccaata tctgtattct catatgtttt gattgttagt tgttattcat
    11701 gatactttgg gctactcaga aaaataatga atgtttgtgt gaatgaggaa gatttgagag
    11761 atttttcaac tgtcttgttg tcatttttta gacgcggagg acgcagattt ataaaagaaa
    11821 atccgctgtc cgccgcatct aaaagatagt aataaggcga ttccgatacc tcttcgtttg
    11881 gtctgcgagg atatattgct tcctttctta gaatttggct tatcggttct cctgacttgt
    11941 tgggccaaca atatattctt tcctcccatc gttgactttg tgggctgctg tatatacact
    12001 gccgtcacgg gtaacctcgt aacctgttac caaataggat tcattgtcgt ccatattcgg
    12061 atttgccggg ttgaaattga tgaacgttcc accggacacc tggatgctgg cagtgttctt
    12121 gtctgtattc tttaagttca gtacccagta tctgccatcc gtgtcgttgt tgggtgtacc
    12181 atatttgccg gattcaaatg ttcctccata gatattgatt ttcccattct ctcttgcata
    12241 aatcaggtct atctgggtgt tcagtttctg ggtgttatag taagaaccgc catgaatatt
    12301 tactgtcccg tgtcctcggg cttcaattac catgcgataa ccatcgtctt tcgctgtagc
    12361 agatgcatcg cacttcacat tgccgttgcc tgaaatgttt agtgttccgt tctgtacagt
    12421 aaagatttgt gtgaaaggag tggcatcagc tgtttctgag gaattgatga tgtcgtggcc
    12481 attcaggttt aagtttgccg ttgcgtttgc agcattcaat atgtagcctg tggcaagctc
    12541 cgtcttggcg atgttgatat ttgagagaag ttttatatcc acagttgcgt tggttgccat
    12601 gtacttcagt acgcttgggt cggagaatgt accnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    12721 nnnnnnnnnn nnncgcttgg gtcggagaat gtaccgccgg taacgttgat gaccggtgta
    12781 taagtggtgc cttctgtgat gagtgacttt gcttcggcaa tcagtgtacc gcctttgatg
    12841 tttactgtgg caatgccata tgctccactt acgttgatgg cggcgcagtc cagtcctccg
    12901 gtaccgtcgc cccagttgcc ggtgctgcct gtgcctttac tggtaatcaa ggctgtgcct
    12961 tccacgttca gagtgcctcg ttggatgcat acacctcctg cggcaccata aaccttgccg
    13021 ccactgatgg tcgttgtgcc ggattggggc agatagactg catagtcagc agtagaaatg
    13081 agttctccgt ctgtgatgtt gatgatggag ttctgcgtct tgtaattgcc gttgcctgcc
    13141 actgcaaacc atccggcttc tatcttgccg cctgtcatgg tgaagtctcc accgtccgtc
    13201 actccgacgc catattggcc gttactgttc ggagtctttc tgactgcact gatgttgccg
    13261 ctttccatgg tcatggaggc atcttcaccg gctatttcaa tcagactgcc attataagaa
    13321 gccgctgtat aatcctggct ggcaactatc ttgcctttct tctcggtaga gctgtccttc
    13381 agtgtcatct tgcccaagac gatgattttg cctgttgcgc tgttgtcggc agtcagtgta
    13441 tatccgttca agtcaagaac cacggacttt ccggcgggta cactgacgct ttgccctgtg
    13501 atgtcggcat cggcggacaa tttaaaatct tcgccgttgg cgaaagcggt ctttaggact
    13561 gccacgtcgg attgaactac aaatttgctg tcgattgttg ccggaagtga tgcttcagtt
    13621 ccttttatta tatagattgt ggtattgccg gcatcgtgta ccaattgttc tacctttcca
    13681 tatatcttca agttaccgcc ttttacggtc agcttcttta cggtgacgcc tgcattgata
    13741 atcaatgtct gctgggcggt agtggcagtc acttcattgt aagtggcttt attgcctact
    13801 gctgccaatg taacggtggt gcttggcatg gtgatggcta cagaaggagc ttcttgctct
    13861 gctgtggttt ccggcacagc caaggataca cagttggtgg cagtggcggc gggagtactt
    13921 acgctggtat tggtcttgtc ggtcagcttt aacggggcag aagtgctggt tgtcggggct
    13981 gtattgaacg ccaggttgat gtccgagttc tgtaaaaccg ggatggcgat gccgtcgttg
    14041 ctgccagaag tggtattgaa gctgccgctg actgcaatgt cggttacggt tgctgctgtc
    14101 ggtgcttctt gtgggagatt ttttgaatca gctaaagctg tactaagcgc actgggggtt
    14161 gtagcctcta ccacaacgca atccaaagga ggtactacca atatgtctct tctgcctagg
    14221 attttgtcat taagcgtctt ggtaaaatat accttgtcgc ttccattcgt cagttgggca
    14281 gtgatggaac tataagtacc tgtgggcaaa ggaatgtaga agttgcgaga ctttatatca
    14341 gctgaggctg tgaaggaggc ggtgatttcc ttgctttcat cgctcgttac tgccagtatc
    14401 gggtctgctg cggttaagtc taccgtacaa gtacctgcaa tgttattgga ggcaataatc
    14461 ttgaaagtag tggcctctgc cggaatcttg ttgacggtca gttttatcat ggctgccatg
    14521 tgcttgaagg acagagcgct cagattgtcg ggatttgtca ccttggcata catcgggcca
    14581 ttgctgctgc cgttataatt tgtaagcgtg gcaggtagag tcatggtcaa tgtattgccg
    14641 cttacgctca tgttttgttg gtaaggatag atggagaata cagccgtttc tccgcttggc
    14701 ttgctgccgt tgaaagtggc ggaagtttga ccagcaccgc ttgcatattc taattttgta
    14761 ttgctataat tactttctgc attactacag aacaacccta gggcatcggt atcttgccat
    14821 agaatcttgt attcatcgtt tacggtagta cgggtgtcgg tacctgcgcc ttcaaacgtt
    14881 gcgttaacgg tgatgtttcc tttccgcccg ctgttttcaa attcctcttg gctgcaactg
    14941 aatgcggtca aggcagcagt tgccatgcag gcaacttgca taaggtttct taatttcatc
    15001 ataatgaagt cccccttagt tttctacggt taagatgtca ttgattaggt cttccaagtc
    15061 gctgctggat gccgaattgt agctatgggt agaggtgctg cccgaatagg agcgcgtaat
    15121 gggatggtaa ggttcgccgc ttgttgcaat gactccttca ttctccattt tgataacttc
    15181 gatagacgga gtgatgtatg cttctctacc gtctggtgtg ttctgtttca tatacacaaa
    15241 ttatttaaag gttaaacaat aaaaaaacgt gaaaactgta tatactaaaa caacaatgat
    15301 tatacttgat gaat
//
