LOCUS       gnlProkkaJNBBPICE_242   3453 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNBBPICE_242.
ACCESSION   gnlProkkaJNBBPICE_242
VERSION     gnlProkkaJNBBPICE_242
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:48:03
            Original ID  :: gnl|Prokka|JNBBPICE_242
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3453
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3453
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[549:3453]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      550..3453
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..3453
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..3453
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..560
                     /locus_tag="ctg242_1"
                     /transl_table=11
                     /translation="MIDGQTILMGFEELLSQFVWYMLGPIRALDYAFEYQYDSFLGLWY
                     GRATVGGFDTLLKMFIHALGGSYTTANQVIGGYLQEHLITVGYGITFNFAYTALIFYYL
                     DFGYFGILLWPFFLGITTRFTVYKFQKKATFARLILMLFFFYTAIFATFSWTFYKTASV
                     VLIILLIIYQKYEQKSLCRHEC"
     CDS             550..1827
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 206;
                     E-value: 1.2e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg242_2"
                     /sec_met_domain="CTP_transf_like (E-value: 2.1e-15,
                     bitscore: 45.3, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.7e-121, bitscore:
                     392.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 8e-66, bitscore:
                     210.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSADIIHPGHLNIIHEAQKYGSVTVGVLTDAAIASYKRLPYLTYE
                     QRSLIVKNLKGVEEVIPQTTLDYVPNLELIKPDFVVHGDDWKDGIQKETRQRVIDTISK
                     WGGKVIDVPYTKGISSTQLNTQLKEIGTTPEIRLKRLKRLISAKKIVRICESHSGLTGL
                     IIENTSVEVNGIKREFDGMWSSSLTDSTSKGKPDIEAVDLTTRLHDLNDALECTTKPVI
                     FDGDTGGKIEHFVFTVRTLERLGISAVIIEDKIGLKKNSLFGTDAVQTQDTIEGFCDKI
                     KAGKRAQITADFMIIARIESFIAGKGLDDAMERALAYIEAGADGIMIHSKDKSGKDIRE
                     FCMTLRKKHKSIPIVVVPTTYNHITEDELASWGVNVVIYANHMLRSAYPAMLNTAKSIL
                     ANARSYEANDLCMPVKEILELIPGTK"
     CDS             1905..2996
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 61.1;
                     E-value: 1.5e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg242_3"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.7e-18, bitscore:
                     53.0, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.2e-21, bitscore:
                     63.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQMDFFTGVPDSLLKNVCAYITDHFVTERNVIAANEGAAVGLAAG
                     YYLATKKIPVVYMQNSGLGNAVNPLMSLTDKEVYNIPLLLLVGWRGEPGVKDEPQHIKQ
                     GKVTLPLLEAMGIKYAIMSQNETEFLSQLNYANFYMNETHEPFAFVIPKGTFEEYKLQQ
                     DGEVILPLKREAAIQLIASSLSKEDIIVSTTGMISRELFEYRTSAFMEHEKDFLTVGSM
                     GHASQIALGIALEKKKCKVFCFDGDGSTLMHMGSLAIIGSLHPDNYVHVIFNNGAHDSV
                     GGQPTVAFNIDLCKIAQACGYEAALSVSDSDSLCEALKRITYMHGPILLEVKVRKGARK
                     DLGRPTTTPLQNKDTFMLFLNNQ"
     CDS             3001..3453
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg242_4"
                     /sec_met_domain="Fe-ADH (E-value: 1.9e-36, bitscore: 113.7,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQRCFLGESSIENLLLVLKEFSFSHLFLVRGRNSYETCGAKSIM
                     TAVFSELDCEVTEYFDFEENPKIEDLERGLLLLRKYSCSVIVAVGGGSVLDMAKLLRFF
                     YSYSGEPTSGKFEKEKDLLPLIVLPTTAGTGSEATHFAVLYKNKVKY"
ORIGIN
        1 ctgatataga tggacaaacc atccttatgg gatttgaaga attgttgtcc caatttgtat
       61 ggtatatgtt gggacctatt agagcgttag attatgcttt tgagtatcag tatgattcct
      121 ttttaggctt gtggtatgga agagcaactg ttggtggatt tgatacactt ttaaagatgt
      181 ttattcatgc gttaggagga agttatacaa ccgctaatca agttataggt ggctatcttc
      241 aagaacatct aataactgtc ggttatggta taactttcaa ttttgcttat acagcattga
      301 tattttatta tttagatttt ggttactttg gaatattgtt gtggccattc tttttgggaa
      361 taacaactcg gtttactgtt tataagtttc agaaaaaagc aactttcgca agattgatat
      421 taatgttatt ctttttttat actgcaatat ttgcgacttt ttcatggact ttttataaaa
      481 cagcttcagt agtgttaatt atattactaa ttatatacca gaaatatgaa caaaaaagtt
      541 tatgtcggca tgagtgctga tattattcat ccagggcatt tgaatattat tcacgaggcc
      601 cagaaatatg gttctgtaac tgttggagta ttgacagatg ctgctattgc tagttataaa
      661 cgtttgccat atttgactta tgaacagcgt tcgctaattg tgaagaattt gaaaggcgtt
      721 gaagaagtga ttccccaaac aactcttgat tatgttccta atttagagtt gataaaacct
      781 gattttgtag ttcatggtga tgattggaag gatggtattc aaaaagaaac tcgtcaacgt
      841 gtcatagata caatttctaa atggggtggt aaagtgatag atgttcctta tacaaaaggt
      901 atatcttcca cccagttaaa tacccagtta aaggaaattg gtactacccc tgaaattcgc
      961 ttgaaacgtc taaaacgtct gatttctgcc aagaaaattg ttcgaatatg tgagtctcat
     1021 agtggattaa caggtttaat tatcgaaaat acgagtgttg aggttaacgg tattaaacgt
     1081 gagtttgatg gaatgtggtc tagtagtctt actgattcta cctctaaagg aaaaccggat
     1141 attgaagctg ttgatttgac tacccgtctt catgatctga atgacgcttt ggaatgtaca
     1201 actaaacccg taatttttga tggagataca ggtggaaaaa tagagcattt tgtatttaca
     1261 gttcgtactt tggagcgctt agggatatca gcagttatta ttgaagataa aattggtctg
     1321 aagaagaact cgctttttgg aacagacgct gttcaaaccc aggatacaat tgaaggtttt
     1381 tgcgataaga taaaggctgg taagcgtgct cagataacgg ctgattttat gataatagct
     1441 cgtattgaga gctttattgc aggtaaaggt ctggatgatg caatggaacg tgcattagca
     1501 tatattgagg ctggtgctga tggcattatg attcatagta aggataaatc gggtaaggat
     1561 attagggagt tctgtatgac tttgcgtaag aagcataaat ccatacctat tgtggttgtt
     1621 cctacaacat ataatcatat aacagaagat gaattagcat catggggagt gaatgtagta
     1681 atttatgcca atcatatgct tagaagtgca tatcccgcca tgctaaatac agcaaagtcc
     1741 attttggcta atgcccgttc atatgaagct aatgatttat gtatgcctgt caaagaaata
     1801 ttagaattga ttccgggtac taaataactt cgtttatatt ctattaattt gagattcttg
     1861 ttattatgat atcttcaaaa tttttcattg attctctttg ctccatgcaa atggatttct
     1921 ttacgggagt tcccgattct ttattgaaaa atgtgtgtgc atatatcacc gatcattttg
     1981 ttacagaacg aaatgttatc gcggccaatg agggagctgc agttggttta gctgcaggat
     2041 attatttagc cacaaaaaaa ataccagttg tttatatgca aaattccggc cttggcaatg
     2101 ctgtcaatcc tttaatgtca ttaacggata aagaagttta caatattcct ttattgttac
     2161 ttgtgggatg gcgtggcgag ccaggagtaa aagatgagcc ccagcatatt aagcagggca
     2221 aagtgacact tcctttactt gaagctatgg gtataaaata tgccattatg tctcaaaatg
     2281 aaacagaatt cttatctcaa ttgaattatg ccaattttta tatgaatgag acacatgaac
     2341 ctttcgcttt tgtaattccc aaaggaactt ttgaggagta taagcttcaa caagatggag
     2401 aggtgatatt acctttgaaa agagaggctg ctattcaact tatagcttct tcattgtcaa
     2461 aagaggatat tattgtctct actacaggta tgatatcacg tgagttattt gaataccgta
     2521 cttctgcttt tatggaacat gagaaggatt ttttgacagt aggttctatg gggcatgctt
     2581 ctcaaatagc attaggcatt gctcttgaga aaaaaaaatg caaagttttt tgtttcgatg
     2641 gtgatggatc aactttaatg catatgggat cgcttgcaat aataggttcc ttacatccag
     2701 acaactatgt acatgttatt tttaacaatg gggctcatga ttctgtaggt ggacaaccca
     2761 cagttgcctt taatattgat ttgtgtaaaa tagctcaggc ttgcggttat gaggcagctt
     2821 tatctgtttc agacagtgat agcttatgtg aagcccttaa aagaattacg tatatgcatg
     2881 gtcctatttt gttagaggtt aaggtaagaa aaggagcacg taaggatttg ggacgtccga
     2941 ctactactcc cttacaaaat aaagatacct ttatgctttt cttgaataat caatgatttt
     3001 atggagcagc gttgtttttt gggagagtct tcaatcgaaa atttgctctt agttttgaag
     3061 gagttttctt tttctcacct ttttttggtg cgtggcagaa actcttatga gacttgtggt
     3121 gccaaatcta ttatgactgc tgtttttagt gaattagatt gtgaagtaac ggagtatttt
     3181 gattttgaag aaaatcctaa aatcgaagat ttggaaagag ggttattact attacgtaag
     3241 tactcttgtt ctgtcattgt cgctgttggt ggaggtagtg tattggatat ggctaaacta
     3301 cttcgctttt tttattctta ttctggtgag cctacaagtg gtaaatttga aaaagagaaa
     3361 gatttgcttc cattgatagt tcttcccact acagccggta cgggaagtga ggcgacccat
     3421 tttgcagtat tgtataaaaa taaagtgaaa tat
//
