LOCUS       c00358_gnlPro..        13114 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNBBPICE_358.
ACCESSION   c00358_gnlPro..
VERSION     c00358_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 05:31:04
            Original ID  :: gnl|Prokka|JNBBPICE_358
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13114
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..999
                     /locus_tag="ctg358_1"
                     /transl_table=11
                     /translation="RELITESRFYLHKIMDTAKVFGECFFYEYYLSIFVTATNKQIYLP
                     MPNSSACRGKKQCAQCPKAVDNAIIYASHLRGFHLPARKCEENIIIFLLKGEVLVNSKE
                     YAGTVLHAGEFILQAIGSKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIF
                     YPLTITPELQLFLESSKAYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQ
                     YTNSFHYFVLQNHAKVKTVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVY
                     ELRYTDASISEICYKYGFESLPHFSNFCKKNFGASPRSLRADNLSEVNGMS"
     protocluster    1..13114
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1137:4608]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1138..4608
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13114
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13114
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(1138..1893)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg358_2"
                     /sec_met_domain="Fer4_7 (E-value: 1.1e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 3.6e-26, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.2e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(1927..3873)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 199.8; E-value:
                     2.7e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg358_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.7e-62, bitscore:
                     199.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1e-37, bitscore:
                     118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEDTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGFGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQEKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             complement(3910..4608)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg358_4"
                     /sec_met_domain="SucD_FumR (E-value: 8.7e-130, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(4771..5673)
                     /locus_tag="ctg358_5"
                     /transl_table=11
                     /translation="MRLETCCNRQIDCMVCPQKSEGVLVYRHYPKGQHFSAEKCTQNCM
                     IFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEYIVYWFTELPLICEER
                     YKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKYIEMKCQELVYILTCY
                     YPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYTTTTFRRLFKNMYGVP
                     VYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCKDSFGDTPRALRKRSA
                     NGEKISIICKEQGKDQEDE"
     CDS             5779..6048
                     /locus_tag="ctg358_6"
                     /transl_table=11
                     /translation="MKKAIFFVYFICLVLSGLSAQNWDINTLNRVNSWDGKFVRNYNKI
                     ISRSEPYVAVGVPVAMAVAAWIKHDKGLLKDAVYVGTSVAGLLL"
     CDS             6057..6380
                     /locus_tag="ctg358_7"
                     /transl_table=11
                     /translation="MKYLVDRERPYDKYPNRVHAYSHEGSPSFPSGHTATAFALATSLS
                     VKYPKWYVIAPSALWACSVGVSRMNEGVHYPSDVLAGAAIGAGCAVVNIYVNKWLNKWL
                     FGE"
     CDS             complement(6463..8085)
                     /locus_tag="ctg358_8"
                     /transl_table=11
                     /translation="MEMMKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVD
                     KVDEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVI
                     QPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVD
                     DQLYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLI
                     LDLQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVD
                     EYSASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRC
                     IQKPYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRT
                     VYGGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFN
                     EKFEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMN
                     STNQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(8108..8566)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg358_9"
                     /sec_met_domain="CTP_transf_like (E-value: 5.5e-19,
                     bitscore: 58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             complement(8563..10497)
                     /locus_tag="ctg358_10"
                     /transl_table=11
                     /translation="MEDNNNMTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVR
                     SGMYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRG
                     IPQGKLVEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRIAI
                     FEKGTLLSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIY
                     NGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTT
                     QGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNN
                     MWPAAPQEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGV
                     TKLARERAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNT
                     QAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGM
                     HIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNP
                     EITRFKGLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINN
                     LVIEEDLAS"
     CDS             complement(10615..11751)
                     /locus_tag="ctg358_11"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             complement(11902..12936)
                     /locus_tag="ctg358_12"
                     /transl_table=11
                     /translation="MKVLYPVCIIFVLKIDIPMDILFLVGGLLLILLGANGLTDGAASV
                     AKRFHIPSIVIGLTIVAFGTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCT
                     ALFAPIAITRNTLKREIPLCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIF
                     LSYTFAIAKRDGSMKEPEKEYLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGAS
                     GIARGLGVSESIIGLTLVAGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLG
                     CSASITPLRLTGITNFDLWVLVGSSILLWLFGIFFGKRIITRVEGNILILCYIAYTAVL
                     IYNL"
     CDS             13051..13113
                     /locus_tag="ctg358_13"
                     /transl_table=11
                     /translation="MKVIRAFCQAIGTQKNEEQSS"
ORIGIN
        1 agagaactta taactgaatc ccgtttctat ttacacaaaa ttatggatac tgccaaagtt
       61 ttcggggaat gtttctttta tgagtattat ttatctattt ttgtcactgc aacaaacaaa
      121 caaatctact tgccgatgcc caactcttct gcttgcagag gtaaaaaaca atgcgctcaa
      181 tgtcccaagg ctgtggacaa tgcaataata tatgcttccc acctcagagg attccatctg
      241 ccggcgcgaa agtgtgagga aaatattata attttcctgc tgaaaggaga agtgcttgtc
      301 aacagtaagg agtatgcggg aactgtgttg catgcaggtg agttcatcct tcaagctatt
      361 ggttccaagt acgaaatact tgccatgacg gatgtggaat gcgtttgtta ccggttcagt
      421 aagcctgaat tcttctgtga ggaccggtat aaccatatta tgaaagaggt tacccctcca
      481 ttgatattct atcctttgac cattactccc gagttgcaac tctttctgga aagttccaag
      541 gcctatttgt ccgaggagaa gatttgccgg gaaatgcttt gtttcaaacg gaaagaactt
      601 gctttcattc ttggaaatta ctactccgac tatgagcttt ccatgctgat acatcctctt
      661 gcccagtata ctaattcctt ccactacttt gtcttgcaga atcatgccaa agtcaagacg
      721 gtagaggaac ttgcccagtt gggaggatat acagtagcta ctttccggcg tatattcaat
      781 tctgtttttc atcaaccggt gtacgagtgg atgatggaac ggaggaagga aagcgtggtt
      841 tatgaacttc gttatacgga tgcttctata tcagagattt gctataaata tggctttgaa
      901 tcgctgcctc atttttccaa tttctgcaaa aagaatttcg gggcttctcc ccgtagcttg
      961 cgtgccgaca atttatctga agtaaacggc atgtcataaa aaaactcctc cggcggtttc
     1021 ccggcagagg agtctcttgt gatattaatc aaatatagtg aaagctgagt gataaatctg
     1081 agcttgctca aaaggtttat ccgaagcgca tcctatatta tttgcagaaa gaccggatta
     1141 gtctttcagt ttcgcaatga taaagtcgcg gttcaggcga gcaatgttgc tgatggaaac
     1201 attcttcggg cattcagctt cgcacgcacg agtgtttgta cagttaccga aaccgagttc
     1261 gtccatcttg ctcaacatag ccttggcacg gcgcaatgct tccggtttgc cttggggcaa
     1321 caggttcagc tggctcacct tggcagaaac gaacagcata gcagaaccat tcttacaagc
     1381 agccacacaa gcaccacaac cgatacagct ggcagcatcc atagcctcgt cagcgatggg
     1441 cttcggaatc aggatagcgt tggcatcctg gggagcaccg gtacgtacgc tgacgtagcc
     1501 gcctgcctgc ataatcttgt cgtaggccgt acggtcgacc atcaagtcct tgataaccgg
     1561 gaaaccggca gagcgccacg gttcaacagt gatggtatcg ccgtcgttga aacgacgcat
     1621 ataaatctgg caagtcgtag cgccggttgc aggaccgtgg ggatgtccgt tgatgtagag
     1681 cgaacacata ccgcagatac cttcgcggca gtcgtggtcg aatacaaccg gttctttacc
     1741 ttcagaaatc agctgttcgt tcaagatatc cagcatttcg aggaatgaag tatcgcccgg
     1801 gatatctttc atttggtatg tttcaaaagc gccttttgct ttcggaccct tctggcgcca
     1861 taccttgagc gtaaatgata tatttttatc cattttcttt aattctttaa atgttcaact
     1921 tcccgattag ctcttgtagt tacgagtctg taccttgatt gcttcgtaaa ccagcggctc
     1981 tttcagcaat accggttcct tttcgtcaga accctgatat tcccagcaag ccacgtagaa
     2041 gtagttttca tcgtcacgct tggcttcgcc ttcttcagtc tgatattctt cacggaagtg
     2101 accgccgcag ctttcgttac ggttcagtgc atcgtaagca accagctcgc ccatagtgat
     2161 gaagtcgtac agacggatag ccttgtcgag ttctacattc ataccttcct tgtcgcccgg
     2221 gatgaacagt tctttctcga actccttgcg gacttctttc agcttcttca gaccttcctt
     2281 caagccttcg gccgtacgtc ccatacctac atattcccac ataatgtggc ccagttcctt
     2341 gtggatagag tctacagact tcttaccctt gatgttcatc atccagtcaa tcttctcctg
     2401 aacggccttt tctgcagctg caaattcggg caggtcggta gagaaacggg gaactgtaat
     2461 ctggtcggcc agatagttct ggatagtgta aggcaatacg aagtaaccat cggccagacc
     2521 ttgcatcagg gcggaagcac cgaggcggtt tgcaccgtgg tcggagaagt tacattcacc
     2581 gatggcgaat agtcccttga tggaggtcat cagttcgtag tcaacccaga taccacccat
     2641 ggtatagtgg atagccggat aaatcatcat cgggttttcg tatgggctga catcagtgat
     2701 ttcttcatac atatcgaaga ggttgccgta acgttgtgca acgacatctt tacccagacg
     2761 gttgatagct tcggagaagt caaggaatac ggcaagaccg gtgttgttca cgccgaagcc
     2821 cttgtcgcag cgttctttgg cagcgcggct ggcaacgtca cgcggaacga ggttaccgaa
     2881 tgccggataa cggcgttcca ggtagtagtc gcggtcttcc tcgggaatat cttttccttg
     2941 cagtgtatct tcctgcagtt tcttggcatc ttccagcttc ttcggaaccc agatacgacc
     3001 atcgttacgc agagattcgg acatcaaagt cagcttagac tgcttgtcac cgtgaaccgg
     3061 gatacaagtg gggtgaatct gtacgtaagc agggttggca aaccaggcac ctttacggta
     3121 gcaagccatt gctgcagagc agttacatgc cattgcattg gtagaaagga agtaggcatt
     3181 gccgtaacca ccggtagcga ttaccacagc gtgggcggca aaacgttcca atttaccggt
     3241 aacgaggttc tttgcaatga taccgcgggc acgtccgtca atgaggacaa cgtcttccat
     3301 ttcgtagcgg gtatacagtt tcacagtgcc tacgttcacc tggcggctca atgcagagta
     3361 tgcacccagc aacagctgct gtccggtctg acccttggca tagaaagtac gggatacctg
     3421 agcaccaccg aaagaacggt tgtccagtgt accgccgtat tcgcgggcga aaggaacacc
     3481 ttgtgcaacg cattggtcga taatattgtt ggatacttca gccagacggt aaacgttggc
     3541 ttcgcgggca cggtagtcgc caccctttac tgtatcgtag aacagacggt atacagagtc
     3601 accgtcgttt tggtaattct tagcagcatt gataccacct tgtgcagcga tggagtgtgc
     3661 acggcgcgga gagtcctgga tgcagaagtt gaatactctg aaacccattt cgcccagaga
     3721 ggcggcagca ctggcaccgg caagtccggt tcctactacg atgatgtcca gacgacgttt
     3781 gttggcaggg tttactaatt tttggtgagc cttataattg gtccatttct cagccaccgg
     3841 tccttccggt attttagaat ctatcttagt cataatgcaa tttacaattt agtcatttac
     3901 aatttgaatt tagcaagcgc cgcacaatga ttttgcaaag aatacgacaa ctaccagagc
     3961 gaagcagagg acaacgatag tagaatagat gttggagata catttccaac ggttaatcca
     4021 tactttgttg ttccagccca aagactgcat ggagctccag aaaccgtgag tgaggtggaa
     4081 ccacaatgcg cccagccaaa cgaggtaaag cactacgaat accggattgc tgaaggtgtt
     4141 ttgaatgtga tagacaccgt tggctgcata tgccagcgtg agggtgtcag catgcatgcc
     4201 catgttgtgc atcaactcgg gaagctgcat tttagcccag aagtttacca ggtgcaggcc
     4261 caaacccacg attacgatga tacccagtac gagcatgttt tgagaagccc attccacagt
     4321 cttgggcttt tccgtaacgg catagcgttc gctaccacgt gccttacggt tctgcatagt
     4381 cagccagaaa gcgtagatga tgtggatgat gaataaggca gccagaccta ccgtagccac
     4441 caatgcgtac cagtttgctc ccaggaactc acaaaccatg ttgtagccat tagccgagac
     4501 taatgcaacc aggttcatcg ccatgtgaaa tgtcagaaac aggacaaggg cgataccggt
     4561 aacgctcatc accactttcc ttcctacaga tgaattactt aaccacataa atgattgaat
     4621 ttaagttatt taatagtttg aaaatttgtt ctatcaggat acttctgtaa atgtttcgca
     4681 aaaataggag aaatccagcg ataaagcaag cgattaaaga aataattccg taatccggca
     4741 gaatgcgaag tttacggaca agtaaaaggt ttactcgtcc tcctggtctt tgccttgctc
     4801 tttgcagata atggaaatct tttctccgtt tgctgaacgt tttctcaggg cgcggggcgt
     4861 gtctccgaaa gagtctttgc agaagtgggc aaagtgggat agggaatcaa agccatagcg
     4921 ggcgctgatg actgaaatgc gttgtttggt gtattgcagg tcgttcagaa ttccttcacg
     4981 tttcttgtcc agaatccatt catagaccgg gaccccatac atatttttaa acagacggcg
     5041 gaatgtggtg gtggtatatc caccgaggtg ggcaaactct tccacattct tcaccttgtc
     5101 gtagttctgc atgacgaaat attggaagct ttccgtataa gtgctgatgg ggtagaagaa
     5161 tgtactgatt tggtgtagcg gatagtagca tgtcaatatg tataccaatt cctggcattt
     5221 catttcaatg tatttgctgc acgcataggg ttgctcgttg aggtagcagg caaggctttt
     5281 caggagccct tcgagcatgg aaatcgcggt aagcggggta taagtcaagg gggcttccga
     5341 gcgtttcagt atctccttgt agcgctcttc gcaaatcaga ggaagctcgg tgaaccaata
     5401 gacaatatat tccacttcgg tcaaagccag gagttctact ttggagccga tggcttgcaa
     5461 gatgagctgg cggctttgga gagtggtgcc cggatattcg tcactgttta caagtaattc
     5521 acctttcagc ataaatatca tgcagttctg tgtgcacttt tcagcagaga aatgttgtcc
     5581 cttggggtag tggcggtaaa ccaatactcc ttctgatttt tggggacata ccatacaatc
     5641 aatctgtcgg ttgcagcaag tttccagtct catgaaatga ttagcgaatt attataaatg
     5701 tggcaacaaa gatagaattt ttttgtgaaa actctatcta tttgtcctat ctttgcgtca
     5761 aactaatata aaggacttat gaaaaaggct attttttttg tatattttat ctgccttgtt
     5821 ttatccggtc tttcggcaca gaattgggat attaacactt tgaaccgggt taacagttgg
     5881 gatggcaagt ttgtccgtaa ctataataag ataatttcac gttcggagcc ctatgttgct
     5941 gtcggtgttc cggtggcgat ggcggttgcc gcttggataa aacatgataa gggtttgctg
     6001 aaagatgcgg tctacgtagg tacaagtgta gcggggcttt tgttgtgact tatggaatga
     6061 aatatctggt ggaccgtgag cgtccttatg ataaatatcc caacagagtg catgcatata
     6121 gccatgaagg cagcccgtct tttccttctg gacatacggc gacggctttt gcccttgcca
     6181 cctcgctcag tgtaaagtat cctaaatggt atgtgatagc tccgtctgcc ctgtgggctt
     6241 gttccgtggg agtttcccgt atgaacgagg gagtgcatta tccgtcagat gtgttggcgg
     6301 gggctgcaat cggtgctgga tgtgctgtgg tcaacatcta cgtcaacaag tggctgaata
     6361 agtggctgtt cggagaatga ttttaggcgc gaattacgcg gaatacgcgg agttagataa
     6421 actaaatccg cataatccgc gcctaagttt gtttcaagtc ggctattgga taatagtgct
     6481 gtagatgcct tcgttcagca cttttagagc ttgctgcacg ctctggttcg tgctgttcat
     6541 cacctggaag tattcgttca tgtcccatag gtcacgggct atcaaggctt taagttgtgt
     6601 cttgatgagc ggtagggatt ggttgtactg tttctcgtca aacttgattt tctctttgtc
     6661 ggcaagcgta cgtatttcgg caaggaagtt atcgtctatc tcgaacttct cgttgaaggc
     6721 ttcgaatttc ttgtatttgt tctgcaactc cttccggtgc ttctcgatgt agccggtagt
     6781 ggctttgata accacgcctt tggctacgag gttgcggtga tagtctgtgt actgggtagt
     6841 gtcgatgggg acgaagaagt cgggcatgat acctccacct ccgtaaacgg tacgtcccat
     6901 acgcttggtc tgtgctttca gggagtcggc aaaatggata ctgtccgcat gaatcatttc
     6961 tccatgattg aagcggtcta tcagttcctg gttatactta tcctgactgt tctcgccggt
     7021 taggcggccg tcgaggttgg cagtgctgtc gtaaggcttc tggatacaac ggcccgaagg
     7081 agtatagtag cgggcgatag tgaggcgaat catggaaccg tccggcaggt cgataggacg
     7141 ctgtaccaat cccttgccga aggtgcggcg tcctactacc acgcctctgt cccagtcctg
     7201 gatggctccg gtcacgattt cactggcaga agcggagtac tcgtccacca atatgatgag
     7261 acggccgttc ttgaagttgc ccgtaccttt ggcaaagaaa tcactgcggc gtgcggccct
     7321 tccttcggtg tagacgatga gttctttttg cttcagaaat tcgttggcaa ggtcgatggc
     7381 ggcattcaga taccctcctc catttccttg caggtcgagg atgaggtctt tcattccttt
     7441 cttttgcagg cttttcagag cttctgcaaa ctcttcggcg gtggttgccc cgaagcggtt
     7501 gatacggata tagccggttt tgggttgtat catgtaagat gcgtccaggc tgaggatggg
     7561 aattttgtca cgcttcacgg tgaagtacag ctggtcgtcc acgccacggc gcacgatggt
     7621 gagtttcact tccgagtctt tcggtccgcg caggcggctc ataatatctt ccgtgctcat
     7681 ttttactccg gcaatggcgc tgtcattgac ggctacgata cggtcgccgg caaggatgcc
     7741 caccttctcg gaaggtccgt tgctcacggg ttgtatcaca agcagggtat cttctatcat
     7801 ctgaaactgt acgccgatgc cctcgaaatt gccttgcaac ggctcgttca tcttcttcac
     7861 ttcttcggcg ttgttgtagg tggagtgcgg gtcgagttgt gccagcatct tgatgatggc
     7921 ttcttccacc agcttgtctt catccacctt gtccacataa aggttggtga tggcaaactc
     7981 tgccatttgc agtttgcgca gggcttcatt gttcggcttt tgcgcttgtg ccgtcaccgc
     8041 gcatatacat attataatag taaatagttt tttcatcatt tccattttaa tccctaatcc
     8101 tttatcctta atccctaatc tccattccct ccggtatgaa catgcttatg tccttgccgt
     8161 attgcagcag ttcgcgcacg gtggtggaac tgacgcaggt aagttccggc tcggtgaaga
     8221 gcaggatggt ttctatgccg gtcagtttgc ggttgatgtc ggcaatggtt tcctcgtatt
     8281 cgaaatcctt cacggtgcgt atgccgcgta ttatcagact ggcatctacc tgccgggcaa
     8341 agtcgatagt caggcagtca taggactgca caatgatgcg cggctcgttc cggtagtagt
     8401 ctcgtatcat ttgttcgcgc ttttccaagg ggaaatacgt attcttattt tcattgatgc
     8461 cgatgcctat gacgatttcg tctataaaag tcagtgcacg gctcactacc gaagagtgac
     8521 cgatagtaaa cgggtcgaat gttcccggaa agatagctct tctcatgatg ccaaatcttc
     8581 ttctataacc aagttgttga taataaagtt ttgtcgttcc atggtattct tacccatgta
     8641 gaattccagc agctctttta cgaggtctgt cttgcgcagg gacacttgtt ccagacgcat
     8701 atccttgccg ataaaatgct tgaactcgtc gggcgagatt tctcccagac ctttgaatcg
     8761 ggtgatttcg gggttgggac ccagttcttc aatggctttc acacgttcct cctctgtata
     8821 gcaataactt gtcttctttt tgttgcgcac gcggaagaga ggggtttgca ggatatatac
     8881 atgccctttc tttatcaggt cggggaagaa ctgcaggaag aaggtgatga tgagcaggcg
     8941 gatgtgcatg ccgtccacat cggcatcggt agctacgatg actttgttgt agcgcagtgt
     9001 ctctatgccg tcttctatat tcaaggctgc ttgaagcaag ttgaattctt cgttttcata
     9061 aactactttc ttggtgagtc cgtaggaatt tagcggttta ccacgcaggc tgaatactgc
     9121 ttgggtattc acgtcgcggc tcttggtgat ggaaccgctg gcggagtctc cctcggtaat
     9181 gaagatgcag gattcggttt cctggtcttt gcctttaccg tcactcaagt ggtagcggca
     9241 gtcgcgcagc ttgcggttgt gcaggttggc tttcttggcg cgttcgcgtg ccagcttggt
     9301 gacgccggca atggctttgc gctctttctc ggagtcttgt atcttttgca gcatcacttc
     9361 ggccacaagc gggttcttgt ggaggtagtt gtccacttcc gtcttgatga agtctcctac
     9421 gtatttgttc accgtggggc cggcgggctt gtgttcctgc ggcgcggcag gccacatgtt
     9481 gttgctgccc agtttcgttt tggtctggct ctcgaacatg ggttcctcca cgtcgatggc
     9541 aatggcggct accagtccgt tgcggatgtc ggcatattcc tggttcttgt tgtagaactc
     9601 cttgatggta cgggcaatgt gttccttcaa ggcagtctgg tgtgtgccgc cttgggtggt
     9661 gtgttgcccg ttgacaaagg agtagtactc ttcgccgtat tggttggtgt gtgtgaaggc
     9721 aatctcgatg tcctctcctt tcaggtggat gatgtcgtaa aggccttcgc tggtcatgtt
     9781 gtctttcagc aagtcctcca gcccgtggcg ggaaacgatg cgctggccgt tgtaaatgaa
     9841 ggtgaggccc gtattcaggt aggtgtagtt gcgcagcagg gtttctacga actggttctg
     9901 gaaggaatag ttcaagaaga gtgtggcgtc cggttcgaag aagatatagg ttccgctttc
     9961 ttctgtcgag tcttcggtca catcactcaa cagcgttcct ttttcaaaga tggcgatacg
    10021 taccttgccg tcgcggtagc tgcgtacttc gaagcggctg ctcagcgcat tgactgcctt
    10081 gatacctacg ccgttcagtc cgacactttt cttgaaagcc ttcgagtcat atttaccccc
    10141 ggtattcagt ttgctgaccg cctctaccag tttgccttgc ggaatgcctc gtccatagtc
    10201 gcgtacgctg acacgcagac tgtcttctat agtcacttct atacgctttc cggcacccat
    10261 cttgaactcg tcgatgctgt tgtccatcac ttctttcagc aacacataga tgccgtcatc
    10321 gttctgtgag ccgtcgccca gacggcctat gtacataccg gaacggacac ggatatgctc
    10381 catgtcgtcc aggtggcgga tgttgtcgtc ggtatattcc acgctggaaa cggggctctc
    10441 tgtgatattg ttgtctgctt cttccagcgg cagggtcata ttgttgttat cttccataag
    10501 tacgttattc cttcatattg cgcattgcga caaaggtaat gagaaattcg ggggttcgca
    10561 aaaaaataat gtcttttatg gacttctgac aagcttatat tctggattta gaacttattt
    10621 tattcctttc acaaagcatc ttctccgttt atgctgttcc gtcttgaagt actcccactg
    10681 cgcttgcacc ttgccgttca gctccagctc cggattactc tcggcatact cgaaaccaag
    10741 ttgctgatag acggggataa ggtcggagaa caacaatgca tttaccccct tgttctgata
    10801 ctccggtttc acggcaacca gcagcaaatc gagcatcttg ggatatttct tcaagaagat
    10861 ggtcttggcc aggtgatacc aacccatagg aagcaggcgc ccgtgggctt tttgcaacgc
    10921 ttcggcgagt gacggcatgg aaatgcctac ggcaagcagc tggtcatcgg catcggtaat
    10981 caatgtcacc atgcgtaggt cgaggatggg caggtacatc ttgacgtatt ggtcaatctg
    11041 ccgttggctc agtgcagaat agccatagag tggctgatag gcttcgttca tcagttcgaa
    11101 gatggcctga ccgtagtctt gggcaatctt cttggcagat gtgtatttct ttaccttgag
    11161 gttatacttg cgctggatga ggtcggagat gcgcttgtgc ttgtcgggta tggcgtcggg
    11221 aatgtagatt ttgtactcca cccaatcggc atccttctca aagcccatgc gttccagatg
    11281 ttgcggatag tagggatagt tataaatggt ggccatggtg ctgagctggt cgaatccttc
    11341 gatgagcata ccttcggcat cgaaatctgt gaatcccagc gggccttgta tatgtgtcat
    11401 tccccgttct tttccccatt cttccacggt gcgaatcagg gcatcggaga cttccgcatc
    11461 atcgatgaag tctatccagc cgaagcggac ttcctttttg ttccaggttt ggtttgcctt
    11521 gtggttgatg atggcagcta cacgtcctac gattttacct tcccgataag ccaggaaata
    11581 gtcggcttca caaaattcga atgcagcgtt tttcttcttg ttgaaggtgt tgagcatgtc
    11641 atcgaaaagg tcggggacgg aataagggtt gtttttgtat agcaggtagt tgaaacggat
    11701 aaagcgctcc agttcccgtc ttgtggttac tttcttgatt gtaattgcca tagttgttca
    11761 atattgagac cacaaaggta atgcaaactg agagcagaac aaaataagct tgcttatttt
    11821 ttatgccgag gtacagcttg ccttatttaa aaatacgtga taatctttaa aataccgcgt
    11881 agggtgtctg taaatttgct gttagaggtt gtatatcagt accgctgtgt aggcaatgta
    11941 gcagagaatc agaatgtttc cttccacccg ggtgatgatg cgtttcccga aaaagatacc
    12001 gaacagccaa agcaggatgc tggaccctac gagtacccac aaatcgaaat tggtgatgcc
    12061 cgtcagacgc agtggagtga tggaggccga acaacccagt acgaagaata tattgaagag
    12121 attacttccg atgacgtttc cgatggctat ttcggggttt ttcttcaagg cggctacgat
    12181 ggaggtggcg agttcgggca gtgaagtgcc gcctgctacg agcgtcagcc cgatgatgga
    12241 ttcgctgaca cccaatccgc gggctatgcc gctggcaccg tctacaaaga aattacctcc
    12301 gatgatgagg ccggcaagtc cgccgagaat gtatagggcg gacttccacg cgggtaacag
    12361 cctgatttcg tcttcttcct gtaagtactc cttttccggt tccttcatac ttccatccct
    12421 ttttgcaatg gcaaaagtat aactcagaaa aatggtaaag aagcatagca gcaataggcc
    12481 gtcggtgatg ctgagtatgt tctccccact gctgtccagt aagacgtcgt tggcacaaat
    12541 cagcagggcg aaggatgaaa ggatgcaaag gggtatttcg cgtttcagtg tgttacgggt
    12601 aatggctatc ggggcaaaaa gggccgtaca acccacaatc atcagggtat tgaacgtatt
    12661 gcttcccacc acattgccaa tggcaatgtc tgcactgcct tttagggcag aggatatgct
    12721 gacggtgagt tccggtgcgg aagtgccgaa ggcaacaatg gtgagtccga tgacgatgga
    12781 cggtatgtgg aaacgtttgg caacggatgc ggcaccgtct gtcaagccat tggcacccag
    12841 aagaatgagg agcagtcctc cgacaagaaa caatatatcc ataggtatgt caattttgag
    12901 tacaaagata atgcaaaccg gatacagaac tttcatgttt gcatgaaaaa gttatgttga
    12961 ttaggatagg aagttaaaaa cattccgtat gtttgaagca tttattgggt atatttgcat
    13021 aattaaagaa tcaaatcaag aagtttatat atgaaggtta tccgtgcttt ctgtcaagcc
    13081 attggcaccc agaagaatga ggagcagtcc tccg
//
