LOCUS       c00023_gnlPro..        13261 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNHCPIJN_24.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 06:31:11
            Original ID  :: gnl|Prokka|JNHCPIJN_24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13261
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13261
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[290:3261]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      291..3261
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13261
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13261
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             291..2519
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_1"
                     /sec_met_domain="Gly_radical (E-value: 7.7e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTDARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLIEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2533..3261
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.9e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_2"
                     /sec_met_domain="Radical_SAM (E-value: 9.3e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKERGIHVCLDSN
                     GGLWNEDVEELFKLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQGKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(3254..3703)
                     /locus_tag="ctg23_3"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(3690..3857)
                     /locus_tag="ctg23_4"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDKVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(3917..4420)
                     /locus_tag="ctg23_5"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVLTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             4614..4844
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             4931..7045
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCRIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKISNRKNLSGSKQQTPPDGTPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEETSAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRRPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(7115..7420)
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(7401..7733)
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             7750..8166
                     /locus_tag="ctg23_10"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPTKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFDFSPHFQINPPIEADFRKYLLSL
                     MCKRSKESDMGNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(8323..8577)
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYISVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGDFK"
     CDS             complement(8595..8729)
                     /locus_tag="ctg23_12"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSEKLLELIDQKKELSSN"
     CDS             complement(8847..10205)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 152.2; E-value: 5.8e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_13"
                     /sec_met_domain="MFS_1 (E-value: 1.1e-46, bitscore: 152.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDSERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     RGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPCNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(10221..11141)
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKNDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQVPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 ggtacaacgg ttttcaagac cgccgcaatc gaccactctg ccacctctcc aaaacttcct
       61 tatcagaagt gcttttcgtt aaaagcggtg caaaggtacg aagatatttt aaacttgcaa
      121 gagttttcac taaaaattta atctaatctt ttcctaagga tagcaattaa taggtatttt
      181 atgttgaaaa gcataaaata gagcatattt atgctgatta tatgaaaaat gattgtaact
      241 ttgtgcgctc taaagaatag gataactaca acctctaatt ttatcatttt atggaattaa
      301 acaagatctt taaagacggt ctttggagca gcgaaatcaa cgtcagagat ttcgtaagtc
      361 ataacatcac tccgtattac ggagatgctt cattcctcga aggacctaca gaacgtacca
      421 aagccgtatg gaaccgctgc ctcgaagcgt tggcagaaga aagagaaaac aacggtgtcc
      481 gctcattaga taatgttacc gtatcaacca tcacttccca caaggccgga tatatcgaca
      541 aggaaaacga actgatcgtc ggcctgcaga cagacgaact tctgaaacgt gccatcaagc
      601 ctttcggagg tatcaacgta gtcagcaaag cctgtcacga aaacggcgtg gaagtggacg
      661 accgcgtaaa agatattttc actcactacc gcaagacgca caacgacgga gtattcgacg
      721 tatatacgga agaaatccgt tccttccgtt cgctgggatt ccttaccgga cttcccgaca
      781 actatgcacg cggacgcatc atcggtgact accgccgtat ggctctttac ggcatcgacc
      841 gtctgatcga agcaaagaag gaagatttgc acaacctcac cggtccgatg acagatgccc
      901 gtatccgtct gcgcgaagaa gtggcagaac agatcaaggc actgaaagac atgaaagtga
      961 tgggcgaata ctacggtctc gacctgagcc gtcccgctta cacggcacaa gaagccgtac
     1021 agtgggtata tatggcttac cttgccgccg tcaaagaaca agacggtgcc gccatgtcac
     1081 tgggtaacgt ttcttctttc ctcgatatct atctggaata tgaactgagc aaaggaacca
     1141 tcaccgaatc gttcgcgcaa gagctgatcg accagtttgt catcaaactg cgtatggtcc
     1201 gccacctgcg tatgcaatca tacaacgaca tctttgcagg cgacccgacc tgggtaaccg
     1261 aatctctggg cggacgtctc aacgacggac gtaccaaagt gacaaagacc tccttccgtt
     1321 tcctgcagac attgtacaac ctcggccctt caccggaacc gaacctgacc gtactctgga
     1381 gcccggaact tcccgaagga ttcaaagaat tctgtgcaaa ggtttctatc gacacttctt
     1441 ctatccagta cgaaaacgac gacctgatgc gtgaagtacg tcagtccgac gactacggaa
     1501 tcgcctgctg cgtatcatac caggaaatag gcaagcagat tcagttcttc ggtgcccgtt
     1561 gcaacctggc caaagccctg ttgcttgcca tcaacggcgg acgttgcgag aataccggta
     1621 cagtcatggt gaagaacatc cccgtactga ccagtgacac gctgaagttc gaagaagtaa
     1681 tggacaacta caagaaagta ctgatcgaaa tcgcccgcgt atacaacgaa gcgatgaaca
     1741 tcatccacta tatgcacgac aagtattatt acgagaaagc ccagatggct cttgtagata
     1801 cgaacccgcg cataaacctt gcttacggtg tagccggact ttccatcgca ctcgattcac
     1861 tgtctgccat caaatatgcg aaagtaactg cccgccgcaa cgatatcggt ctgacagaag
     1921 gcttcgacat cgaaggagaa ttcccttgct tcggtaacga caacgacaag gtagaccacc
     1981 ttggcgtaga cctggtatac ttcttcagcg aagaattgaa gaaattgcct gtttacaaga
     2041 atgcccgtcc taccctctcc ttgctgacta tcacttccaa tgtgatgtac ggcaaaaaga
     2101 ccggtgctac tcccgacgga cgtgccaaag gtgttgcctt cgctccgggt gccaacccga
     2161 tgcacggacg cgacaagaat ggtgcgatcg cttctctgag ctctgtagcg aaacttcgtt
     2221 accgtgactc acaggacggt atcagcaaca ccttctctat cgttccgaaa tcactgggtg
     2281 ctacggacga agaccgtatc gagaacctcg taacgatgat ggacggttac ttcaccaaag
     2341 gtgcccacca cctgaacgta aacgtactga accgtgatat gctatacgat gccatggagc
     2401 atccggagaa ctatccgcag ctgaccatcc gcgtttccgg ttatgccgta aacttcgtga
     2461 agttgagccg cgaacaccaa ctggaagtta tcagccgtag cttccacgaa cgtatgtaat
     2521 ctattactct atatgatgat aaacgtacat tcatacgaaa gtatgggaac attcgacggg
     2581 ccgggcttac ggctcgtcgt ttttcttcaa ggatgcaact tccgctgcct ctattgcgcc
     2641 aatccggata cgatagcagg aaagggaggc acgcctaccc caccggaaga aatcgtccgc
     2701 atggcaatga gccagcgccc cttcttcggg aaacgaggag gaatcacttt ctctggaggc
     2761 gaaccgacgt ttcaggcgaa agcactcgtc ccgctggtcc gcgaactgaa agaaagaggc
     2821 atccatgtct gtctggacag caacggagga ctttggaacg aagacgtaga agaattattc
     2881 aagctgaccg atcttgtgtt attggatata aaggaattca atcccaaccg ccatcagacg
     2941 ctcaccggaa gaagcaacga gcaaaccatc cgcacggccg cctggctgga agaacaggga
     3001 aaacctttct ggctgcgtta tgtgctagtg cccggataca gcgattttga agaagacata
     3061 cgcgcactgg gagaagcact cggaaaatac aagatgatcc aacgggtgga aatactgcct
     3121 taccatacac tgggcgtaca taagtacgaa gcgatgggac aggaatacaa gatgaaaggg
     3181 gtaaaagaaa atacccccga acagcttgaa aaagctgcgg aggtattcaa agagtatttc
     3241 actacggtag tagttaatta atggagaatt ctccaatgac ctcaaagcaa gggcattctt
     3301 taatccgttc ccaaggatct acgatcccat tatagttggt gtcgggactt aaatcccgat
     3361 gccctactac tttagcttcc ggataacgct gcaacaattc gtgtaccaag cgatgtagcg
     3421 cctccttctg acggggtgta cgcgtatccg ccgcttttcc attctcatcc agaccgccct
     3481 catagcatac acctaagctg atcgcattgt agccacgtgc atgagctccg accgtatctt
     3541 catcccgcat cggctcaatc tcgcccgact tgcgtatata ataatgatac ccccagcacg
     3601 aaaagccacg ataacggtga gccgtatcca catcctttgc cgtaaagtcg caatcgacac
     3661 gggtggcgga acaatggatc acaatcagac taatctttct catgttcctt ttccctttcc
     3721 gtcgttttca ctttgcacac ctccttacaa gtagtatgat agcgcacttc tctcaccacc
     3781 ttgtcccgct ttctctttcc gaagaaagga atcagataca tgatcacatc taaaatccgg
     3841 tttactattt ctttcatctt atcaaaatat taatggaagt tattctaatt cgttattacc
     3901 ttgacccgtc tgccaattat accgtagggt ccggagcctc ttcatcaccg gagccatcac
     3961 caccggaatc cggattcttg tcagggtctt ctcccccgcc atcgcctgca cccgcctgcg
     4021 ccaccgcacg agtcagcact tgctggtaac tcagaatctt catcaattcc gccagcgttt
     4081 taccggggcg gaaaataaga tgcgccccct taatcatcga accggaaaat tccttgaccg
     4141 atgccgcacc ttcactgttc agtcctatct gcaaactgcc caaatcaccc agtctcgcaa
     4201 ttcttcctgc cttcaacgca cgcttcactt cgtaaagaat acccgaaata gccgcacgta
     4261 catccgtttc cgtacaagta gaacgactgg tgatcgcttc gcacaactct tcaaagtcca
     4321 gctcacccga cgcctgcgcc tgtgcataat actttgccgg ttcactcttt tttgcaggat
     4381 tcttgcgcgg caccactgaa taagatactg tcattgccat aataaaataa ttttaaagtt
     4441 tataatacgt aggatgcatc cctttcttgt taacagcaca aagataagga tagccggaca
     4501 agccatattc cccaacgaag tttcttgatt cccaacgaat aaaaatgaag tcaaaccttt
     4561 gaaaaacaag gaattttatg taactttata gcataaaaca agaagaaaac atcatgaatt
     4621 acaaagaaga ttctttcctt atccgcacct ataccaaagc ggaactggct cacctttaca
     4681 atccccatgt ctgcctcaaa gttgctttac aaatacttcg tcgttggatt atttacaacc
     4741 tccctctcct gcacgaactc gaacaggaag gctaccgcgc acgcaaccgt ctcctttcgc
     4801 cgaaacaagt ggcaactatc atacactttt tgggcgaacc gtagtaactt attgccattt
     4861 tatacaaagt tcctttacac atttccgcaa agaagttcct ttgcatcgac aaacaataat
     4921 caaaataaaa atgaaacatt tcaccatatt tcaaggtttc tactacgcaa tagcagagat
     4981 gaccgaagaa gaaatagtgt ccactatcgg cagttttacc taccgggaaa aagtcgaaga
     5041 aatacgccgc atctttgcag agcaaggaga aaaggctgcc aatgagaaga aaaaagaatt
     5101 gccggcaatc gccttctccg ccagctaccg aggaaggcgt accaaagtga acctcgtcaa
     5161 atatctggga cacatcgtga tagacatcga ccacctcagc aaagaagaat tggcacgcat
     5221 cctccctatc atcaagagat gcgattacac ccgcatcgcc tttatcagtc ccaaagggat
     5281 gggcgtgaaa atcatagtgc gcgcatgcca tccggatgag acattgcccg aaacccttca
     5341 ggaaatagaa gacttccatc atgcagctta caccagactc gtttcttttt acaccgaact
     5401 ctgtcggata gaaatcgaca cctccggtca ggatgtggca cgcacttgtc tgttctctta
     5461 cgatccggag atctatttca atccgaacgc tgacgctttt cttgtagatc aacctcaggc
     5521 atcctacaag atttcaaatc gtaaaaatct ctccggcagt aaacaacaga ctcctccgga
     5581 cggcaccccg acgaatgaag acacagcact caacgcccat tccgccaacg cttctttggt
     5641 gttgacttta acttactatc acaacaagtc cgaaaaatac atagcaggca accggaacaa
     5701 ttatctgcac catctctcat gtaccttcaa tcgctacggc attccgcagg aggaaacatc
     5761 cgcctttatc aaaagccagt ttacagactt tccggcggac gagacagtct ctttgatcaa
     5821 tagcgcctac gctcataccg acgaatttaa tacctgtaaa ctgaatggca cgcagaaacg
     5881 aatattacgg atagaacaat atatcagcga gcactacgaa acacgctaca atgaagtgct
     5941 gcatatcatg gaatatcgca gaaggcgtcc cgacaccgag aaaccggagc ctttccgcat
     6001 cttggatgag atgatggaaa acagtatctg gatagaaatc aacgagctgg gatatccctg
     6061 cactgtcaaa acaatcgaaa atctgattta ctccgatttc agccagtcgt atcatcccat
     6121 tcgcgagtat tttgaattac tgcccgaatg ggacggaacc gactatatcc gtatcctggc
     6181 ggatagtgtc cagacgagtc atcaggagtt ttgggcggaa tgcctggaac gttatctggt
     6241 ggcgatgtgc gcagcggcta ctcaggagaa tattgtcaat cacacggtac ttctgctatg
     6301 cagcgagata cagaacatag gaaagactac ctttatcaat aatctcctgc ctcccgaact
     6361 gcgtgcttat ctctctaccg gactaatcaa ttcgaacaat aaagatgatt tagccaaaat
     6421 aacgcaggcc atgctgatca atctcgacga gtttgaaggg atgagcggtc gggaactgaa
     6481 tgcattcaaa gatttggtaa cgcgcaaagt gatcagtttc cgtctgccat atgcacgccg
     6541 ttcgcaaaac ttccctcata cggcctcttt tgcaggaacc tgcaattatc aggaagtgct
     6601 tcacgacacg acaggcaacc ggcgtttcct ttgttttcat ccttattcca tccaatttat
     6661 taccatcaat tatgcgcagc tctatgctca gatcaaatat ctgctgaata agccggggta
     6721 ccaatactgg ttcacgcaag cggacaatga acggcttgaa gagaataacg aggctttcat
     6781 ctttcattca ccggaagaag aaatggttct tacgcatatc cgcaagccgg aacgttttga
     6841 gaaggtttat tatctgactg tcagtgagat tgcggaacta atacgtgagc gtaccggtta
     6901 tcagtattcc atcggatcaa aaatacagtt ggggaaggtg atgactaagc accattttga
     6961 atctaaaaaa ggaaataacg ggcgccgata tgccgtattt attatagata tcgagcaggt
     7021 aaaatcaaac aggctgtatg aatagaagcg ggaaagcctt gtgaatatag caaaatgcag
     7081 agtcatcttg acagatactc tgcatttatt gtttttacaa aatcattgaa aattcgattt
     7141 tacagcctaa cgcattcatt atacgataga aagtagatac tttaggctct gtctgaccac
     7201 tttctactct tgaaatataa gaacggtcag agccgatacg ccgggctaat tcagcctgag
     7261 tgattttagc cttttttctt gcgtcctcga taatctgtcc tgtataaaag gcgtaggcct
     7321 tttcttctgc ctctgcacga gaagctgttc cttccttacc aaaacgctca tctattaatg
     7381 cactgacatt aaagaattcc tcatttgttt ttgcttccat aatactcctt tcttaatatc
     7441 tttgctttat caatttcttt ctttggtgtt ttttcggttt tcttttgaaa accgttaaac
     7501 agaatcacaa tacgcccttc gtcgaaacaa aagaatattc tatatatatt gctttggtac
     7561 tcgatacgaa gttcataaag tccttcttct atcaaccgca taaatttcaa aggtattctg
     7621 tcttgtgtct gcaataacat tagcacatac aatatcttat cttgggtgcc agcatctaaa
     7681 ttttcaaaga attctttgaa gtatccttta tatgctatta tttctctttt cataacgcaa
     7741 atataagaaa tgttgttcaa ctatacaaca catttcctcg ttttatatta tttttcatca
     7801 tcttcaccca caaaagtgag aggagtgaga gaggaattga aactttttct attttatttc
     7861 tttatttcta ctttctatat ttctctaaaa aaaatacgaa tgttagaaat cctctctcac
     7921 tcctctcact ttttaccttt tctttctcca aaaagacggc gggaaatcgg aaaaacacaa
     7981 ccgtcttttt tcgatttctc accgcatttt caaatcaacc caccaattga agcagacttc
     8041 aggaaatatt tgttatcttt gatgtgcaaa agatcaaaag aatcagatat gggcaacttg
     8101 atgcgtaaac ttcctattgg aatacaaacc tttgaagata tacgaaggaa gaatatctta
     8161 ttgtaaagat cggagtggaa tttagttcag aaagccggaa cttaaaccgt tggttaatag
     8221 agactattga gtaatagaaa cccaagtggc ggcaatctgc aacaagtttc catccagatt
     8281 tccgccactt ttttaattca accgttcagc gatggaaaca gattatttaa aatctccctc
     8341 cgaataatct gaaaactccc cggcacgttc tttcttctca tacgagacca acgtttcgat
     8401 actaagcgct ttcccgttct tagggcttat gacatctatc acacttgaca aggaccggaa
     8461 cgtctgttcg caattcgcgt ctccattata cgtcaacctc ccccggtcaa tagcacctag
     8521 aatgacagaa atgtaccgtt tcggatctcc ccgatattcg ataacagtgg gcgtcatttg
     8581 ttcttcttcc cgaatcagtt ggacgacaat tctttttttt ggtcaatcag ctccaacagt
     8641 ttttcactat gcacactgat ttgtgcatct acttcacgaa gttcattctt caatgaacaa
     8701 aacaattcat cactcaatga attttccata aaaacgattt ttattaatta taaaaaagcc
     8761 attccggaaa gcacagctat tgcctgcttc ccgaaatggt gactaatacc ttcaaaaaca
     8821 atgactctat ttttacttta atgtactcaa tttatttcac ttcttttctc tcctgcattc
     8881 caaaccaaca aagcaaacac tactgaaagc aaggctgcac caatccaaaa ccaattgata
     8941 tatgtaaaat cgtaaacttc tactccattt tgcaccgtct tctgaccttc gatcagaatg
     9001 ccactcatca catcctgcaa accggctcct atataactcg ctataccgac aactcccaaa
     9061 gcggctcccg aagcattgca gggagcaata tcgaccgcca tcagtcctcc taaaaaacaa
     9121 atcagcactc caatgcccaa accgaagagc accatcgcca aagcatccac ccaaaaatgt
     9181 acccccggaa ccaatagaaa caaacaaaga gcagacacat tcattaatcc gaatatcaaa
     9241 gccggaacat tacgactgcc agcaaaaaac ttatctgaaa taatacctga gaaaaccgta
     9301 cctacaattc cgcatacaga actgatagat ataataaaac tagcatccaa agtagaataa
     9361 cctttttgcg cttccagata gaaaacaccc cagctattga ctgcataacg gctgatatac
     9421 ataaaagcac tggataatgc aagaatccaa atagcaggat tcttcaaaac tgctttctga
     9481 gctttattga attcctcggt ttgtttaccg gaaacggaat gagcatctga cgtcccccgc
     9541 cgatctagca aaaagccctg actttgaggc gtatcacgca taaaagcaag catcatcaga
     9601 aaaccaagca aaccaatcac tcccgcaccg atcatcccat aacgccatcc catccaactg
     9661 accagcaaag cgatggatat aaaagtcaga gcttcaccca aattgtggct ggccgaccaa
     9721 aagccataaa aagtacctcg ctctttacta ctataccaac gagtcagcga cacaactcct
     9781 gatgctgccc ccatcgactg aaaccaacca ttcaaccccc aaaggagaac aaaagcaaag
     9841 aaggaattcg tgaatcccag acataagttg atcagagcag aacacaataa tccggtagac
     9901 ataaaacgct ttacattgct acggtcagca agaaagccat tggtcagctt accgacggca
     9961 tatacgaaaa aaaggcagga accgataatc cccagttggg tttcggtaaa aactccgtct
    10021 tctacaatcg gtttacggat tacattcata ctcaaacgac aaacataata aatgccatat
    10081 ccggtagtgg cagacagaaa ggtagcccaa cgaatacgct tgaaacggac agagcgttcc
    10141 gaatcagtct ctcccccgga caccggagga gagattttat aaaaatccaa tagtttaaat
    10201 cccataaaga agtctatatt ttaatgatac gcatcttgcc cgttttcact acgcttctta
    10261 cgcgattgca aatattccag cagataggca gtacggtctg tctgaatgat ggccgctccg
    10321 agtgtatcga tcagataacc atatccttcg tccggattct ccaacgattt atcatcatca
    10381 tgtccgccag ccatcgtatc ccacaacgta ttataccaga ttttactttt tcctttcaac
    10441 ttcgttttta cttgcttggg gacctggcag gtatccgata caaatagaag ttcaaaagct
    10501 acgggatgca gctccgtcat aaaatcatcc agttgcttca ttgctcccgg cttatccaaa
    10561 tgaatgatag gcatataaat gatacggtcc agatatttac ctaagtcgtt ctttacgtct
    10621 gccacaggct tggaaccttt catgataatc tgatccactg ttcccgtctt ttcgaggatg
    10681 gggaaaatct cgtcaaatat cggatatgct ttatccagat tgaccatcac acgacctttg
    10741 gcaacccata aagcctcttc caaagtaggt acacgatgct tggttttgag tgccgctcca
    10801 ttcttcagat agagtgtccg gatagaatcc aatgtccatt cggctacctt tccttttccg
    10861 gtagtcgttc ggtccagcgt tttgtcatgc atcaggatca attgaccgtc tttggttttc
    10921 tgaacatcca gctccactac gtcagctccc agacgaatgg aactttcaat agcggcaagt
    10981 gaattttcgg gtgcgtaacg ccagtctgcc cgatgagcta caaccgtgat ttctttattg
    11041 tcagggttcg ttatcttcgc ataaatggct ttcaccggtt cgtctgccga caggcagaaa
    11101 ggaaatgcga ataagattcc tatcattata tatttcttca tatctatatg tactattatc
    11161 tgtatccttt agactttaaa tatttggcag ctacttcagc atagtctgtt tgcacaatgt
    11221 tgatgcgttt gttaatcatt cccaccaaac cggagtagtt ttccgacaac atattggtat
    11281 cattcgctcc gacaatgttg gagaaaagaa gccagccttg atctttaatc tcattaacca
    11341 tcgttccacc catagcgtct gacgtagaca gctgcatcat ttgtacatta tcagtgtagg
    11401 atgaggagaa gtatgtgata tcatcggcgg cttttgccat cgggtgcaac agcaaactac
    11461 tgttggctgt cttcaaatca aatgcataat tgcgattgtt ggatacatac agcaaagtgg
    11521 aaccttccat atccaatttt ttaagcaatg cgacgatcgt atttaccgca acattcttgt
    11581 tgacaatatc cagattataa taaacttttc cttttccctt cttcatcgct tcctccaaag
    11641 tcgggattcg ttcgccagtt atattgccgg atgcatcttt cagataaaat tgttgtaatt
    11701 gctgataagt aaagtctccc accgcaccgc taccgtttgt tgtccggtcg atggtgttgt
    11761 cgtgcatcaa taccaacaca ccgtcagagg tcggccgtgc atccagttcg atcatctcaa
    11821 ctcctgcttt gaccgagtgt tctatcgcag gtaacgagtt ttcgggaatc ccctctttca
    11881 tccctttttg ggtatttcca cgatgcgcgc agagccacac tttataagag gtgctttcaa
    11941 acagactctt taaatctgct ttcaaattcc ccgtcatagg caactgtcct ccttcttctc
    12001 caccgggatt ctctccattc cctcccgatt gggctccgga gtgacgtctg tccttccctt
    12061 tcatcggcca ggcagaggtt gcggccccgg taattccctc atcttccaaa gctactaaca
    12121 cgctctttgt agggtccacc gtattggtga ctccgatata aatcgctcca tccggtccga
    12181 tggtaggcga actccagatt ttaccgattc ccgcttccca atctcctttt aaaggagagt
    12241 cactttcact aatcaacgca gcaaggtctt ttttcagaat caattgttca tccgattctt
    12301 ccggtttaat gatataataa ttgccggact gggtgccgaa atgtatgttt cctgcttgat
    12361 caattgccgc acaaccgctt acatcttccg caatgccgta atgccattgg atagctcctc
    12421 ccggagacaa agagatgatt cctccggttg cttcccccgg agcacgtttc actgtaacga
    12481 taatgcttcc gtcgagtcct atcacaacac cgccttgatc cagcgtgccg acattgccca
    12541 aaggagtacg ccacttctcc actccatcac ttcccatagc aaatgcgcta cttcccattc
    12601 ctgcaaacgt agctgttccg taaatagtac cagcctcatc tactgccgga gaaccgttca
    12661 tattttctga cggcttatca tcgccggagc taaatacctg ccaagcccac attacatttc
    12721 caccggcatt caacgcagaa gcagaagccc cgaacaatcc attctttccg ccaccccaaa
    12781 ctaaagtgtt gtttgccaat actattccgg cagatactcc tccggaagga cctccggaat
    12841 tatccgcatt cgctacgtat cctacccgat agccggtcac cttatctact gcaagcactg
    12901 atcctgtaga accgccatta cccatatata catgattctc accaatggca caggtcaggt
    12961 aattgatacg gggtgtggaa gcgtttcctt tattccagaa gcccttttca gcgtcacctg
    13021 ccaccagcca tttcttactc ccgtccggat ttattgcata cacacgtcct actttgccac
    13081 tggtgtctcc tgttcctacg tagattgttc cgtctatatc aatgcttgga gtagtatgcg
    13141 tatttccgga tggtgcatcg ccgtcagcag atgtccaaag gtcaaattcc caaagctggt
    13201 ctcctgtcgc tgccgaaaat ttacgtaaat aatgatcatt ggaagtcata tacaccccat
    13261 t
//
