Select genomic region:
Overview
3.1
5.1
12.1
15.1
57.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaLCCNBEID_3 (original name was: gnl|Prokka|LCCNBEID_3)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | RRE-containing | 173,005 | 193,792 |

gnlProkkaLCCNBEID_5 (original name was: gnl|Prokka|LCCNBEID_5)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | arylpolyene | 139,016 | 160,516 | flexirubin | Other | 24%

gnlProkkaLCCNBEID_12 (original name was: gnl|Prokka|LCCNBEID_12)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | thiopeptide | 137,769 | 164,090 |

gnlProkkaLCCNBEID_15 (original name was: gnl|Prokka|LCCNBEID_15)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 15.1 | arylpolyene | 51,379 | 77,589 | flexirubin | Other | 24%

gnlProkkaLCCNBEID_66 (original name was: gnl|Prokka|LCCNBEID_66)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 57.1 | RiPP-like | 40,646 | 52,820 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | RRE-containing | 173,005 | 193,792 |
Region 5.1 | arylpolyene | 139,016 | 160,516 | flexirubin | Other | 24%
Region 12.1 | thiopeptide | 137,769 | 164,090 |
Region 15.1 | arylpolyene | 51,379 | 77,589 | flexirubin | Other | 24%
Region 57.1 | RiPP-like | 40,646 | 52,820 |

No secondary metabolite regions were found in these records:
  gnlProkkaLCCNBEID_1 (original name was: gnl|Prokka|LCCNBEID_1)
  gnlProkkaLCCNBEID_2 (original name was: gnl|Prokka|LCCNBEID_2)
  gnlProkkaLCCNBEID_4 (original name was: gnl|Prokka|LCCNBEID_4)
  gnlProkkaLCCNBEID_6 (original name was: gnl|Prokka|LCCNBEID_6)
  gnlProkkaLCCNBEID_7 (original name was: gnl|Prokka|LCCNBEID_7)
  gnlProkkaLCCNBEID_8 (original name was: gnl|Prokka|LCCNBEID_8)
  gnlProkkaLCCNBEID_9 (original name was: gnl|Prokka|LCCNBEID_9)
  gnlProkkaLCCNBEID_10 (original name was: gnl|Prokka|LCCNBEID_10)
  gnlProkkaLCCNBEID_11 (original name was: gnl|Prokka|LCCNBEID_11)
  gnlProkkaLCCNBEID_13 (original name was: gnl|Prokka|LCCNBEID_13)
  gnlProkkaLCCNBEID_14 (original name was: gnl|Prokka|LCCNBEID_14)
  gnlProkkaLCCNBEID_16 (original name was: gnl|Prokka|LCCNBEID_16)
  gnlProkkaLCCNBEID_17 (original name was: gnl|Prokka|LCCNBEID_17)
  gnlProkkaLCCNBEID_18 (original name was: gnl|Prokka|LCCNBEID_18)
  gnlProkkaLCCNBEID_19 (original name was: gnl|Prokka|LCCNBEID_19)
  gnlProkkaLCCNBEID_20 (original name was: gnl|Prokka|LCCNBEID_20)
  gnlProkkaLCCNBEID_21 (original name was: gnl|Prokka|LCCNBEID_21)
  gnlProkkaLCCNBEID_22 (original name was: gnl|Prokka|LCCNBEID_22)
  gnlProkkaLCCNBEID_23 (original name was: gnl|Prokka|LCCNBEID_23)
  gnlProkkaLCCNBEID_24 (original name was: gnl|Prokka|LCCNBEID_24)
  gnlProkkaLCCNBEID_25 (original name was: gnl|Prokka|LCCNBEID_25)
  gnlProkkaLCCNBEID_26 (original name was: gnl|Prokka|LCCNBEID_26)
  gnlProkkaLCCNBEID_27 (original name was: gnl|Prokka|LCCNBEID_27)
  gnlProkkaLCCNBEID_28 (original name was: gnl|Prokka|LCCNBEID_28)
  gnlProkkaLCCNBEID_29 (original name was: gnl|Prokka|LCCNBEID_29)
  gnlProkkaLCCNBEID_30 (original name was: gnl|Prokka|LCCNBEID_30)
  gnlProkkaLCCNBEID_31 (original name was: gnl|Prokka|LCCNBEID_31)
  gnlProkkaLCCNBEID_32 (original name was: gnl|Prokka|LCCNBEID_32)
  gnlProkkaLCCNBEID_33 (original name was: gnl|Prokka|LCCNBEID_33)
  gnlProkkaLCCNBEID_34 (original name was: gnl|Prokka|LCCNBEID_34)
  gnlProkkaLCCNBEID_35 (original name was: gnl|Prokka|LCCNBEID_35)
  gnlProkkaLCCNBEID_36 (original name was: gnl|Prokka|LCCNBEID_36)
  gnlProkkaLCCNBEID_37 (original name was: gnl|Prokka|LCCNBEID_37)
  gnlProkkaLCCNBEID_38 (original name was: gnl|Prokka|LCCNBEID_38)
  gnlProkkaLCCNBEID_39 (original name was: gnl|Prokka|LCCNBEID_39)
  gnlProkkaLCCNBEID_40 (original name was: gnl|Prokka|LCCNBEID_40)
  gnlProkkaLCCNBEID_41 (original name was: gnl|Prokka|LCCNBEID_41)
  gnlProkkaLCCNBEID_42 (original name was: gnl|Prokka|LCCNBEID_42)
  gnlProkkaLCCNBEID_43 (original name was: gnl|Prokka|LCCNBEID_43)
  gnlProkkaLCCNBEID_44 (original name was: gnl|Prokka|LCCNBEID_44)
  gnlProkkaLCCNBEID_45 (original name was: gnl|Prokka|LCCNBEID_45)
  gnlProkkaLCCNBEID_46 (original name was: gnl|Prokka|LCCNBEID_46)
  gnlProkkaLCCNBEID_47 (original name was: gnl|Prokka|LCCNBEID_47)
  gnlProkkaLCCNBEID_48 (original name was: gnl|Prokka|LCCNBEID_48)
  gnlProkkaLCCNBEID_49 (original name was: gnl|Prokka|LCCNBEID_49)
  gnlProkkaLCCNBEID_50 (original name was: gnl|Prokka|LCCNBEID_50)
  gnlProkkaLCCNBEID_51 (original name was: gnl|Prokka|LCCNBEID_51)
  gnlProkkaLCCNBEID_52 (original name was: gnl|Prokka|LCCNBEID_52)
  gnlProkkaLCCNBEID_53 (original name was: gnl|Prokka|LCCNBEID_53)
  gnlProkkaLCCNBEID_54 (original name was: gnl|Prokka|LCCNBEID_54)
  gnlProkkaLCCNBEID_56 (original name was: gnl|Prokka|LCCNBEID_56)
  gnlProkkaLCCNBEID_65 (original name was: gnl|Prokka|LCCNBEID_65)
  gnlProkkaLCCNBEID_67 (original name was: gnl|Prokka|LCCNBEID_67)

Compact view
gnlProkkaLCCNBEID_3 - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 173,005 - 193,792 nt. (total: 20,788 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaLCCNBEID_5 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 139,016 - 160,516 nt. (total: 21,501 nt) Show pHMM detection rules used
Region on contig edge.
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
NRPS/PKS substrates
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg5_102: X
  AMP-binding (70..293): X
  nrpys: Asp, Asn, Glu, Gln, Aad
  SVM prediction details:
    Predicted physicochemical class:
      N/A
    Large clusters prediction:
      Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      YMRMVITSSK
    Nearest Stachelhaus code(s):
    Stachelhaus code match:
      0% (weak)

gnlProkkaLCCNBEID_12 - Region 1 - thiopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 137,769 - 164,090 nt. (total: 26,322 nt) Show pHMM detection rules used
thiopeptide: ((YcaO or TIGR03604) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Thiopeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Thiopeptide predictions
Lists the possible core peptides for each biosynthetic enzyme. Predicted tail sequences are also shown, if present.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.
No core peptides found.
Thiopeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its possible molecular weights and the scores for cleavage site prediction and RODEO. If relevant, other features, such as macrocycle and amidation, will also be listed.
No core peptides found.
gnlProkkaLCCNBEID_15 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 51,379 - 77,589 nt. (total: 26,211 nt) Show pHMM detection rules used
Region on contig edge.
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaLCCNBEID_66 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 40,646 - 52,820 nt. (total: 12,175 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.