LOCUS       gnlProkkaEEEOBLMJ_48   13094 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EEEOBLMJ_48.
ACCESSION   gnlProkkaEEEOBLMJ_48
VERSION     gnlProkkaEEEOBLMJ_48
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 04:33:02
            Original ID  :: gnl|Prokka|EEEOBLMJ_48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13094
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13094
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2806:3094]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2807..3094
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13094
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13094
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..350
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MLLRRSCWYITRCPSSSRMTATRFTRPLWVTSPALAMASSRVMRS
                     PSTEKVPVLPTAPRTEYLKLRNSSDTSGSLIYFPSMMRLRIRAVTSLTFSPSTCSLPRM
                     GKLMFPSTSTR"
     CDS             296..649
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MQLAQDGETNVPFHVHTVAFLHGSGLRHRAVGTHREGPAARVERD
                     GQLGVLAAHGDVQAVVGMHHRLIPGVIRIAEPHLHVLQVDEFLRRTAGGEQEHCHRHNP
                     KTVFSFHCFLCFI"
     CDS             complement(667..1023)
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MVSVYGTPWSGKTPCYRNERRPVAGIVRLQQSGTNRFTPLEGPEA
                     FAALLPSCSAIRQDIRLHDELCRILIRVTEQVPVGRLECLPDREAAWLCFESLYVRDAK
                     AREVRDGLPENGGL"
     CDS             1093..1665
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MPGVRALARAALAEEKVAPAFQADAGGMDGNGVPPECRLGVEDAE
                     HGRQYLPHGRVLHPEEGRGIVKSSVHSHEMCATIHRAVTYLRPVTAGNAQKAYMPHVVG
                     RLVQQLRAFPVIRKGTGVGKQPENPFPFRAFPAPERTEGGQQRLCVQPTGKDDGECQPR
                     HPEKIFVSHLRFPIISLTEIQNASLRA"
     CDS             complement(1605..2612)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_5"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.3e-33, bitscore:
                     108.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVRQTVTGIVCRGLHHLPEALLPGDALMIRWVAETDRIERKNRR
                     MDAVVCLLAQRMGRNGLHPVLLKGQGVAAFYEHPLTRECGDIDLCFLSEEEEREAAELM
                     RRVGCRTEKQPDGSNCYSWQGVEVEHHTRLFDLHNPLLKVYLSALVREHGFTEFRPGGR
                     DGLPEGNQSGEFPATISVPSPLPNLLLLNAHLLKHLLGHGVGLRQFCDMARAYHTLCGS
                     YSPEGLEAVYRRTGLLRWSAQLHTFLTEYLGLHRAELPYADTDACSSPELLRIVLEGGN
                     FGQYGGTKGKASQARWERKLRTFLSFWKHRGFSSAYARKEAFWISVRLIIGNLR"
     CDS             complement(2748..2852)
                     /locus_tag="ctg48_6"
                     /transl_table=11
                     /translation="MGEDGAAVPAGHRRLNAYTERTKASCDPLPECLL"
     CDS             complement(2807..3094)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_7"
                     /sec_met_domain="PF05402 (E-value: 1.8e-14, bitscore: 45.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.5e-09,
                     bitscore: 27.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKSNLKLRRIGNRHMIVEVSDSCVNLTNVYSLNGTAARLWEMV
                     CNGEGRTAGELAEGLCKTYDVEYGRALRDVERQIEEWEKMGLLSRRGTGD"
     CDS             complement(3084..4106)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_8"
                     /sec_met_domain="Glycos_transf_4 (E-value: 6.3e-25,
                     bitscore: 79.7, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIERLVALLLLFAGEFAYLRIADRFNIIDRPNQRSSHKKNVLRG
                     GGIIFLLGVWMYAFLNTTGYPLFIGGMTLIASVAFIDDVCSLSPRFRFFVQFVAMFLLL
                     QEAGMLVENKVWFLLPTMILGVCIINAYNFMDGINGMTGAFSLMVLFTFWLLNREMAFI
                     DATLIELLMISALVFCFFNFRNQAICFAGDVGSVGMAYCVIFILLKLVLFTGNVTYLLF
                     LVVYGIDTVLTIFHRLLLHENLLQPHRKHLFQLLANEGGHSHVTVSITYVLLQLAISLG
                     YIYLPIDKWLYSVIVTIGLVTAYLIIERKLYPKHKEYLKSLSCAVMDEGYSEKCLRNEN
                     "
     CDS             complement(4127..5302)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 151.5;
                     E-value: 6.4e-46)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_9"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.2e-38,
                     bitscore: 122.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCVHGGNCLKNYCLLPFESAMKILHLGKFYPLKGGMEKAILDIVR
                     GISMQGVTCDLLCVSTEKAGVFPLNEHAHIYAMPSVCNVNSVRISPLLIPTLRKLCPNY
                     DIIHIHCPNPMANLALYLSGYRGKVVLHWHSDILKQKYALKLYKPLQTWLIRRADVIIG
                     TSPVYLENSPFLRGMEHKFRIVPLGCEAIVPSADRVSDIRKQYKGKRIIFALGRLIAYK
                     GFRFLIEAARYLDDGYVVLIGGTGPLYNKLLKQINEENLQGKVCLLGYVTDDEVAQYYG
                     ACDVFCLSSVWKTEAFGLVQIEAMSCGKPVVATNIEGSGVPWVNRNGYSGLNVEPENPE
                     ALAKAIMKITSSEEAYRTYSRQARAHYNKMFVKERMLAGYEQVYASLYHEK"
     CDS             complement(5250..6440)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_10"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.2e-12,
                     bitscore: 39.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTSGKCTVRYNESLLYFLFYSNMGNNAKLIVVSAVGLRQGGTLT
                     ILKECLQYLSTCVREGHVRVIAIVHDRRLAEFNGIEYIELPDVIKSWTRRLWCEYITMH
                     RISQRLPGIDLWLSLHDTTPRVIAKRQAVYCQTSFPFYKRTWRDFYFNYKIALFSLFTR
                     YAYRINVHRNQYMIVQQSWLREGLSRMLGVGKEKFIVAPPRRMAVKVETESVNLPCFTF
                     LYASAPDCHKNFEVLCQAARLLEKEKGKGCFKVVVTLSGKENRYTRWLYKNWHDVNSIE
                     FAGYMNKEKLYGYYQAAHCLVHASKVETWGLPISEFGETGKPMLLADLPYAHATASGFH
                     AVGYFNEHKPEELKRLMKEMLEGDHRSLSSQPSTAIKGLYVCSWRELFEKLLPASI"
     CDS             complement(6424..7491)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 172.4;
                     E-value: 2.8e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_11"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.3e-46,
                     bitscore: 149.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNKANYLAAHGYEVTIVTTDQRGRRPFFALDGRIECVDLDVNYE
                     TNNGKSFFNKLVHYPFKQLKHKRRLTKVLNLIKPDITVSMFCNDVAFLPSIQDGSKKVL
                     EVHFSRFKRLQYDRKGLWRLADKWRNRNEQRQVACFDKFVVLTHEDKDYWEGHANIEVI
                     PNAQTFACDVPAALESKTVVAVGRYTYQKGFDMLLRAWRRVCDSIDDWQLHIVGEGEMK
                     ESLQQQILDLSLEDRVELCPATSDIQSVYREASVLVLSSRYEGFGMVLLEAQTAGVPTV
                     SFDCKCGPSDIVADGVTGYLVPANDIPALAEKLLVLMRDETLRKQMGRNAFADASRFSE
                     KAVMQRWTDLFENFR"
     CDS             complement(7548..8840)
                     /locus_tag="ctg48_12"
                     /transl_table=11
                     /translation="MIHFIAIILTGIACSLYMFPFSFTFLPVGNTKIYLAVCGLVLFFL
                     NQIRNRQQVSSHFMVTVSLAAFVVSLICIVSLLYNETNDTTYAIYIIQMWVWTGGAYFV
                     TRCMKSVHGNVTVELIAFYVVGVCAIQCFFALMNEFIPVFKGWVDTYVEQETANLNRLD
                     RMYGIGASLDTGGSRFACALILLSHILMRYANKNNGRIILLAFLFIFIFITGNMVARTT
                     LAGGIIAILYLLYCLREGINGSAQKVFLLFAAVLAVTIPILTSLYYSSVEVKDMFRFAF
                     EAFFNLSEKGSIKTGSTNDLLLMWQQVPQELRTWIIGDGYFLSPHFTNPYYTGHLYGAY
                     HMGTDVGYLRFIFYFGITGLLAFAYFFVLCTRECRKKYPAHKVLFILLLVMNYVLWIKV
                     ATDLFFIYALFLVADDSMAEEDECSTVRQVA"
     CDS             complement(8837..9421)
                     /locus_tag="ctg48_13"
                     /transl_table=11
                     /translation="MPMPCYADAETALRGMLSGTMRWNLWLYMIKRDLYLMNDIHFMEG
                     ENVGEDMLVLIKLFSHAKSIGFVKDAFYHYVKQNENSLTRLSPEQQMKRQMRNLQAATD
                     YLVTHFIGKYEKEINFFKLNAKMPLLISNDKNSYRTWTACFPEANKYIMANKRQTLRMR
                     LVQLMAAKRQFWLVELYYQLVFKFVYGILYK"
     CDS             9434..9820
                     /locus_tag="ctg48_14"
                     /transl_table=11
                     /translation="MPKTEIPPASYNILLPLFRSHHHLLYRIRLYPIVRIHPIHILSRC
                     GSQPCFPCSSYTTIRLVMKYSDLLLKLRIAFGHLQEHLYTPVRATIIYEYIFYLRITLS
                     EKRIGTSCNEVLYLVKWCDDTNNH"
     CDS             complement(9817..10788)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 79.9; E-value: 3.9e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_15"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-40,
                     bitscore: 129.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQGKVSVIVPAYNAARLLERCVRSITGQTYPALEVIVVDDGSKD
                     DTGKIADQLAAEDSRIRVVHKTNGGVSAARNDALKLVEGEWITFVDSDDYLEPDFLRSL
                     LDGEVADLVIGGYHTVGANEIPSANYPTDTAHSPEAIKRALEARLTDMTFLCPWGKLFR
                     TSLVRSLRLIFNTEMKVGEDVVFVWSYLAHCSSLAFKQGQGYDYYTEPGADFKYALDET
                     VSLQTIERILGVLDGLKRNFGMDTEHARCHVLNYYIWLFKLYVNRNYLLRDLARMKNFF
                     YYPLILDYYKTYRRTSKDKLLVYLLLKLRLSGVLYLMIKLYY"
     CDS             complement(10800..11735)
                     /locus_tag="ctg48_16"
                     /transl_table=11
                     /translation="MTSVLNSFWLGIKVPLRKAVYWLQYNLLKRKRNAFNILMAEETID
                     YIVKHECSVCRYGDGEIDMITCLKEGFDESRKSDFQTYDEKLAWRLKQILGNGSDEELN
                     LIVCIPYVWKSHRSLSFTARRFIERSFVNNREMIFASIHPTRLYGDSYFTRFYIDARNK
                     KKKGSYIQHCRQIWQGRDLCIIEGEQSRLGVGNDLFDNAQSIERILCPALDAFAKYDEI
                     MKAACTVNKAKLVLIALGHTATVLAYDLAEVGYQAIDIGHIDIEYEWFLMRAPKKVPVP
                     HKYVNEVPEGRQFSEERNKEYLSQIIYSVK"
     CDS             complement(11744..12220)
                     /locus_tag="ctg48_17"
                     /transl_table=11
                     /translation="MFRRKAMISTGGFVAFPLAFFTDDATWSKLSGNGVACSMQPLFMF
                     RFSGINISSNKETSDRMLLKLKACFLYADWMKTYLKRIECKNEQEKAFMQNILMGLKYK
                     QLEWINWTTCRTNFKDFMKVYRNKEYRNICGTARWFVLLLRNINERFFVRKDYY"
     CDS             complement(12285..12710)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_18"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.8e-22,
                     bitscore: 70.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPFVSVVLPAYKATCLKEAVHSILSQTYRDFELIIVNDASPENVK
                     EVVAKFQDERLAYYENEYNVGGKDLVKQWNDYCLPKTSGEWVVMASDDDMYAPTYLEEM
                     VKLTEKYSQYDLFHCRVNKINIFFWGGNRYVCTFSRI"
ORIGIN
        1 gctccttgct gcgcaggtcg tgctggtaca tcacccgctg cccgtcctcc tcacggatga
       61 ccgccacacg gttcacccgg cccctttggg tgacatcgcc cgccttggcg atggcctcca
      121 gcagggtgat gcggtcgccc tccaccgaga aggtgccggt gttgcccacc gcgcccagga
      181 cggaatactt gaaattgagg aactccagcg acaccagcgg gtccttgata tacttcccgt
      241 cgatgatgcg gttgcgtatc agggcggtca cctcgctcac cttcagcccc tccacatgca
      301 gcttgcccag gatggggaaa ctaatgttcc cttccacgtc cacacggtag cctttcttca
      361 cggcagcgga ctccgtcacc gcgccgttgg cacccaccga gaaggccccg ccgcccgcgt
      421 tgaacgggat ggacagctcg gggttcttgc tgctcacggt gatgtccagg cggtcgttgg
      481 catgcaccac cgcctcatac ctggtgtcat acggatagcc gagccccatc tccatgtcct
      541 gcaggtagac gaatttcttc gacgaactgc aggaggagag caggagcact gccaccgcca
      601 caatccaaaa acagtctttt cttttcattg ctttctttgc tttatttagg gtttatcaat
      661 catcgttcat agtccgccgt tctccggcag gccgtcccgt acttcccggg ctttcgcatc
      721 ccgcacgtac aggctctcga aacagagcca tgcggcctcc cggtcgggca ggcattccaa
      781 ccgtccgacg ggcacctgtt cggttacccg tatcaggata cggcaaagtt cgtcatgcag
      841 gcggatgtcc tgacggatgg cggagcagga gggcagcaat gcggcgaaag cttccggccc
      901 ctcaagcggg gtgaaccggt tcgtgccgga ctgttgcagg cggacgattc cggccacggg
      961 acggcgctcg ttcctgtagc agggtgtctt cccgctccac ggcgtgccgt agaccgatac
     1021 catgccgtcc tctatccgca gcacgggatt gtcgtcattc agcaggcggc agtccggaaa
     1081 ggcctccagc cattgccggg agtgcgtgct cttgcccgtg ccgctcttgc cgaggaaaag
     1141 gtagcccctg cctttcaggc tgacgcagga ggcatggacg gaaacggcgt cccgcccgag
     1201 tgccgcctgg gcgtagagga tgcggagcat ggacgacagt acctccccca tggacgggtc
     1261 ctccacccgg aggaaggccg tggcatcgtc aaaagcagtg tccacagtca tgagatgtgc
     1321 gccaccatcc atagggccgt aacttatctc cgtccggtaa ccgccgggaa tgcgcagaag
     1381 gcatacatgc cccatgtcgt tggacgactc gtccagcagc tccgcgcgtt tcccgtcatc
     1441 cgcaaaggga cgggtgtcgg caagcagccg gaaaatccgt tccccttccg ggcattcccc
     1501 gcaccggaac ggacggaagg agggcagcag cgtctctgcg tccagcccac cgggaaggat
     1561 gacggagaat gtcagccccg ccaccctgaa aaaatattcg tttctcatct gaggtttcct
     1621 attatcagtc ttaccgaaat ccagaacgcc tccttgcggg cgtaggcgct ggagaagccg
     1681 cggtgtttcc agaaggagag gaaggtacgc agtttccttt cccaccttgc ctgggaagcc
     1741 ttgcccttgg tgccgccgta ctgtccgaag ttccctccct ccagcacgat gcgcagcagt
     1801 tcgggagagg aacatgcatc cgtatccgca taaggaagtt cggcgcgatg cagcccgagg
     1861 tattccgtca ggaatgtatg gagctgcgcg ctccacctga gcaagccggt ccgcctgtaa
     1921 acggcttcca gaccctcggg ggagtagctt ccgcacaggg tgtggtaggc ccgcgccatg
     1981 tcgcagaact gccgaaggcc gacaccgtgc cccagcaggt gtttcaggag gtgggcgttc
     2041 agcaacagca ggttcggcag gggcgacggc acggagattg tcgctgggaa ctccccggac
     2101 tggttgccct ccggcagccc gtcccttccg cccggacgga actccgtgaa cccgtgttcc
     2161 ctgaccagtg cggaaaggta gactttcagc aacgggttat gaaggtcgaa cagccgggta
     2221 tggtgttcca cctccactcc ctgccagctg taacagttgc ttccgtccgg ctgtttctcc
     2281 gtccggcacc cgacccggcg catcagctcc gcggcttccc gttcctcctc ttccgaaagg
     2341 aaacagaggt cgatgtcccc gcattcgcgc gtcagcggat gttcatagaa ggcggccacg
     2401 ccctggcctt tcagcagtac gggatgcagg ccgttacggc ccatccgttg cgccagcagg
     2461 cataccaccg cgtccatcct cctgttcttc cgctcgatgc ggtcggtctc cgccacccaa
     2521 cgtatcatca gggcgtcgcc gggcagcagc gcttccggca ggtggtgcag gccgcggcag
     2581 acaatgcccg tcacggtctg gcgcaccgcc atccggtaca cgttccacca ctgcgcgtcc
     2641 gtaagcggga agggtgacag gtcgtccggc tccctctccc acagccccgc acgcagcagg
     2701 ctgaacaacg ccttatgttc cgaagaaagc tccatggaat ccgttttcta aagcaggcac
     2761 tccggtaagg gatcacaaga tgcctttgtc ctttcagtgt aagcattcaa tcgccggtgc
     2821 cccgccggga cagcagcccc atcttctccc attcctctat ctggcgttcc acatcgcgca
     2881 gggcgcgccc gtattccaca tcatacgtct tgcagagtcc ctccgccagt tcccccgctg
     2941 tacggccttc cccgttgcag accatctccc agagccgggc ggcggtcccg ttcaagctgt
     3001 acacgttcgt caggttcacg caactgtcgg agacttccac aatcatgtgg cggttgccta
     3061 tcctgcggag tttcaggttt gatttaattt tcattacgca agcatttttc tgagtaccct
     3121 tcatccataa ctgcacatga caatgattta agatactcct tatgtttcgg atataatttt
     3181 cgttctataa tcagatatgc cgtaaccaaa ccgatggtaa caattacgga gtacagccac
     3241 ttgtcaatcg gcaggtatat atagcctaac gatatggcca attgcaaaag cacataagta
     3301 atagagactg tcacatgtga atgtccccct tcattagcca acaactgaaa caggtgcttg
     3361 cggtgcggct gaagcaggtt ttcgtgcaac agcaaacgat ggaaaatcgt caacaccgtg
     3421 tcaataccgt ataccaccag aaataacaga taagtgacat tcccggtgaa aagcaccagt
     3481 ttcagcaaaa taaagattac acaatacgcc attcctacag aaccgacatc acccgcaaaa
     3541 cagatggcct ggttcctgaa attaaagaag cagaatacca aagcggatat catcagcaat
     3601 tctatcaatg tggcatctat gaaagccatt tccctgttga gcagccagaa agtgaacaat
     3661 accatcagac tgaatgctcc ggtcataccg ttgattccgt ccatgaagtt gtaggcattg
     3721 atgatgcaaa cacccagtat catggtaggc agtaaaaacc aaaccttgtt ttctacaagc
     3781 attccggctt cctgtaatag caggaacatt gccacaaact ggacgaaaaa gcgaaacctg
     3841 ggagacaggg aacatacatc gtctataaaa gccacactcg caatcaaggt cattcctcct
     3901 atgaacagag gataaccggt cgtattcaga aaggcataca tccagactcc taacagaaag
     3961 atgatacctc ctccccgtaa tacgttcttc ttgtgtgagc tgcgttggtt gggacggtct
     4021 atgatgttga atctgtccgc aattctcaga taagcgaatt caccggcaaa cagcaacaac
     4081 aatgcaacta atcgttctat aaacatatat ctttagattt tagagtttac ttttcatgat
     4141 acagggaagc gtacacttgt tcatatccgg ccaacatacg ttccttgacg aacatcttgt
     4201 tataatgtgc acgtgcctga cgggaataag tgcggtatgc ctcttccgag cttgtaatct
     4261 tcataatggc ttttgccaag gcttccggat tctccggttc cacattaagg ccggaatatc
     4321 catttctatt cacccaggga actcccgaac cttctatatt ggtcgccacc acaggcttac
     4381 cacacgacat ggcttcgatc tgtaccaaac cgaacgcttc ggttttccat acggaactca
     4441 ggcagaacac gtcacaggca ccataatatt gcgccacttc atcatcggta acatatccta
     4501 aaaggcaaac tttcccttga agattctcct catttatctg tttcaataat ttgttgtata
     4561 gaggcccggt accaccgatc aacacaacat aaccgtcatc caaataccta gcggcctcta
     4621 taagaaagcg gaaccccttg taggcaatca gacgtcctaa agcaaatatg attcttttcc
     4681 ctttatattg ttttctgata tcgctaaccc tatctgctga cggaactatg gcctcacacc
     4741 ccaaaggaac gattctgaac ttgtgttcca ttccgcgcaa aaacggtgaa ttctctagat
     4801 ataccggtga cgtgccgatt atcacatccg ccctccttat caaccatgtc tgtaacggct
     4861 tgtaaagttt cagggcatat ttctgtttca atatgtcgct atgccaatgc aatacgacct
     4921 tacctctgta accggacaga taaagtgcca gattggccat aggattcggg caatgaatat
     4981 ggataatgtc gtaattcggg caaagctttc tgagtgtggg tatcaataag ggggaaatcc
     5041 tcactgaatt gacattacaa acagaaggca tggcataaat atgggcgtgt tcatttaacg
     5101 gaaacacacc ggctttttct gttgaaacac ataacaggtc acacgtgacg ccttgcattg
     5161 agatacctct tacaatatcc agtatggctt tctccattcc tcctttcaac ggatagaatt
     5221 ttcctagatg tagaattttc atagcagatt caaatggaag caggcagtaa tttttcaaac
     5281 agttcccgcc atgaacacac atagagtccc tttatggcag tcgaaggttg ggatgataga
     5341 gacctatgat ccccctccag catttctttc ataagtcttt tcaattcttc cggtttgtgt
     5401 tcattgaagt agcctacggc atgaaagccc gaagctgtag catgagcata aggaagatct
     5461 gcaagtaaca tgggtttgcc cgtttcaccg aattcggaaa tcggcaagcc ccaggtttct
     5521 actttggaag catgtaccaa acaatgtgcg gcctgatagt aaccatataa cttttcctta
     5581 ttcatatatc cggcaaactc gattgagttc acatcgtgcc agtttttata aagccagcgg
     5641 gtataacggt tttcttttcc ggacagcgtg accaccactt taaaacagcc ttttcctttt
     5701 tccttctcca aaagcctggc ggcctgacat aatacctcga aattcttgtg acagtccggt
     5761 gcggaagcat ataggaatgt gaaacaaggc aaattcacgc tctccgtttc cactttgact
     5821 gccatacgtc ggggcggtgc tacgataaat ttctctttgc ccacgcctaa catcctgcta
     5881 agtccctccc ttagccatga ctgctgtact atcatatact gattacggtg aacattaatc
     5941 ctgtaagcat aacgggtgaa cagtgaaaat agggctatct tatagttgaa ataaaaatca
     6001 cgccacgtcc gcttataaaa aggaaaagaa gtctggcaat agaccgcctg tcgtttggct
     6061 atcacacgag gggtggtgtc atgcagtgaa agccataaat caatcccggg taatcgttga
     6121 gaaatgcggt gcatggttat atattcgcac cataaccggc gagtccaact tttgatgaca
     6181 tccggcaatt caatatactc aatgccgttg aactccgcga gccttctgtc gtgtacaatg
     6241 gctatcacac gtacatgccc ctcacgtaca caggtagaaa gatattgcag gcactctttc
     6301 agaatagtca aagtacctcc ctgacgcaat ccgacagcag acacgactat gagttttgca
     6361 ttgtttccca tattagaata aaaaagaaaa tataaaagac tttcgttgta acggactgta
     6421 catttaccgg aagttttcaa ataaatccgt ccatcgttgc atgacagcct tttccgaaaa
     6481 gcgggatgcg tcggcaaaag cattacgtcc catctgtttg cgcaaggttt catcacgcat
     6541 taatacaagc agtttctctg ccaaagccgg tatgtcattt gccggcacca aataaccggt
     6601 tactccgtcg gcaacaatat cggaagggcc gcacttgcaa tcaaagctga ccgtaggtac
     6661 acctgcggtc tgcgcttcga gcaataccat accaaagccc tcgtaacggg acgacagaac
     6721 tagcacggaa gcttcccgat aaacgctttg aatatcgctg gtggcaggac atagctcgac
     6781 acgatcttcc aacgataaat ctaaaatttg ctgttgcagg ctttctttca tttccccttc
     6841 acccacaata tgcagctgcc aatcatcgat tgagtcgcac acccgtctcc atgctcgcaa
     6901 cagcatatcg aaccctttct gataggtgta acggcctact gccaccaccg ttttactctc
     6961 caaagcggcg ggaacatcac acgcaaatgt ctgtgcatta ggaataacct ctatatttgc
     7021 atgcccttcc caataatcct tatcctcatg cgtgagaacc acaaatttat caaaacaagc
     7081 cacttgcctc tgctcattcc ggtttctcca tttatcagcc agcctccaaa gtcctttgcg
     7141 gtcgtactgc aaacgcttga agcgggagaa atgcacctca agcactttct tgcttccatc
     7201 ctggatggaa ggcaaaaaag cgacatcgtt acaaaacatg gaaacagtaa tatccggttt
     7261 gatgagattc aatacctttg tcagacgacg tttatgtttg agttgcttga acggataatg
     7321 aaccaactta ttgaaaaagg attttccgtt gttggtctca tagttcacat ccagatccac
     7381 acactcaatc cgcccatcca aagcaaaaaa aggtctgcgt cccctctggt ctgtggtcac
     7441 aatggttact tcataaccat gtgctgccag ataattggct ttgttactca atacacgctc
     7501 cataccaccg gaattgcagg tgccggatat gcaatatacg attctcatta tgcaacctgt
     7561 ctgactgttg aacattcatc ttcttctgcc atagaatcat ctgccaccaa gaacagagca
     7621 taaataaaga agagatcggt agccactttt atccacaata cataattcat caccagcagg
     7681 agtatgaata acaccttatg tgccggatat tttttacgac attcgcgtgt gcacaacaca
     7741 aagaaatagg caaaagccaa taatcccgtt atgccaaaat aaaatataaa acgaagatac
     7801 cccacgtccg tgcccatgtg gtatgcccca tacaaatgcc cggtataata aggatttgta
     7861 aaatgtggag aaaggaaata accgtcaccg ataatccatg tccttaactc ttgcggaacc
     7921 tgttgccaca tcaacagtaa gtcatttgtt gaaccggtct tgatgctacc tttttccgac
     7981 aagttaaaga atgcctcaaa ggcaaagcga aacatatcct tgacttccac agaagaatag
     8041 tataaagaag taagaatagg aattgttact gccaacacag ctgcaaataa caaaaaaacc
     8101 ttttgagcag aaccgttaat cccttctctc agacaatata atagatacag aatggcaatt
     8161 atgcctcctg ctaaagtagt acgggccacc atattacccg taataaatat gaaaataaat
     8221 aagaatgcta acagaataat ccgtccattg tttttattcg catatctcat caatatatgc
     8281 gatagcaata tcaacgcaca agcaaaccgg ctacctcctg tgtccaagga agctcctatt
     8341 ccatacatac gatccaatct gttcaagtta gccgtttcct gttccacgta tgtgtccacc
     8401 catcctttaa ataccggaat gaactcattc atcaaggcaa aaaaacattg aatggcgcaa
     8461 acacctacaa cataaaacgc tatcaattct accgtcacgt tgccatgcac tgacttcata
     8521 catcgagtaa cgaaataggc tccacctgtc catacccaca tctgtatgat atagattgca
     8581 taggtggtat cattggtctc gttgtataac agcgacacaa tgcagatcag cgatacgaca
     8641 aaagcagcca gggaaaccgt caccatgaaa tggctggaca cttgttgcct gttacggatc
     8701 tgattcagaa aaaacaatac caacccgcac accgccaaat aaatcttagt attaccaacc
     8761 ggtaagaaag taaatgaaaa cgggaacata tacaaggaac aggcaatccc cgttaatata
     8821 atagctataa aatgaatcat ttgtatagta ttccgtaaac aaatttaaat accagctggt
     8881 aataaagttc caccagccaa aactgccttt tcgcagccat cagttgcacc aatcgcatac
     8941 gcagggtctg ccttttgttc gccataatgt atttgttggc ttcggggaaa caggccgtcc
     9001 atgtccgata agagttttta tcgttactga tgagtagcgg catcttggca ttgagcttga
     9061 agaagttgat ttccttttca tacttcccga taaaatgggt gaccagatag tccgtcgcag
     9121 cctgcaagtt acgcatttga cgtttcatct gttgttcagg actaagcctg gtgaggctat
     9181 tctcgttttg ttttacataa tgatagaatg cgtcttttac gaatccaata ctcttcgcat
     9241 gtgagaataa tttaataagt accagcatat cttcccctac attttcccct tccatgaaat
     9301 gaatatcatt cattaaatac aagtcacgtt ttatcatata gagccacaag ttccaacgca
     9361 tcgttcctga taacattcct ctcagagctg tttctgcatc agcataacaa ggcatgggca
     9421 ttcgccgctc attttgccta aaacagagat accacccgca agctataaca tccttctgcc
     9481 cctgttccga tcgcaccacc atcttctcta tcgcatccgg ctctatccaa tcgtccgcat
     9541 ccacccaata cacatactct cccgttgcgg cagccaaccc tgtttcccgt gcagcagcta
     9601 caccacgatt agactcgtga tgaagtattc tgatttgttg ctgaagttgc ggatagcgtt
     9661 cggccacctg caagagcacc tctacactcc tgtccgagct acaatcatct acgaatatat
     9721 attctatctc cgtataactt tgtcggaaaa gcgaatcggc acatcgtgca atgaagtcct
     9781 ctaccttgta aagtggtgtg atgatactaa caaccattaa taataaagct ttatcattag
     9841 atacaggaca ccggacaacc gcaatttcaa aagcaagtac actaacaatt tgtctttaga
     9901 tgtccggcgg taagttttat aataatcgag tatcaacgga tagtaaaaaa aattcttcat
     9961 ccgcgctaaa tcccttagta gataattacg atttacataa agtttgaaca accatatata
    10021 atagttcagg acatgacaac gggcatgctc tgtatccatg ccgaagttcc gtttcaatcc
    10081 gtccaataca cccaaaatcc gttcaatggt ctgcaaagaa acagtttcat ccaacgcata
    10141 cttgaaatcc gctcccggct cagtataata gtcgtatccc tgtccctgtt tgaaagccaa
    10201 tgaagaacaa tgagccaaat aactccacac gaataccaca tcttcgccca ccttcatctc
    10261 cgtattgaaa atcagcctta acgaccgtac cagagaagtg cggaacagct tcccccacgg
    10321 acacaaaaac gtcatatcag taagccgggc ttccaatgct ctcttaatag cttccggaga
    10381 atgagctgtg tcagtcggat aatttgcact tggtatttca ttggccccta ccgtatgata
    10441 accacctatc accaaatccg caacttcacc gtcaagtagg gatcgcagga aatccggttc
    10501 cagataatcg tcggaatcca cgaaagtaat ccattccccc tctactaatt tcaatgcatc
    10561 gttacgggca gcacttactc caccattggt tttatgaacc acccggatac gactatcctc
    10621 cgctgcgagt tgatctgcta tcttacccgt atcatccttg ctgccgtcat ccacaactat
    10681 cacctccaaa gccggatatg tctggcccgt tatgcttcgt acacaacgct ccaataaccg
    10741 agcagcattg taggccggaa caataaccga aactttaccc tgcaacattt ctttcatctc
    10801 tatttcacac tgtatattat ctgagaaaga tactccttgt tccgctcctc cgaaaattgt
    10861 ctgccttccg gcacttcatt cacgtattta tgcgggacag gtactttttt gggcgctctc
    10921 atcagaaacc attcatactc gatgtcaatg tgcccaatat caatagcctg gtatcccact
    10981 tcagctaaat catatgccag aaccgtagcg gtatgtccca aagcaatcaa aacgagtttt
    11041 gccttattca cggtacaagc tgccttcatt atttcatcat acttggcaaa agcatccaat
    11101 gccgggcaaa gtatgcgttc tatactctga gcattatcga acaagtcatt gccgacacct
    11161 aaccggctct gttcaccttc tatgatgcag agatcgcgtc cctgccatat ttggcggcaa
    11221 tgctgtatat agctcccctt ctttttttta ttacgagcgt ctatatagaa ccgggtaaaa
    11281 taggagtctc catagagtcg tgtaggatga atggaagcaa atatcatttc ccggttattt
    11341 acaaagctcc gctcgatgaa ccgtctggct gtaaaagaga ggcttcgatg gcttttccat
    11401 acatagggaa tgcacactat caaattcagc tcttcgtccg atccgtttcc caaaatttgc
    11461 tttaaacgcc atgctaattt ttcatcgtat gtttggaaat cacttttacg actttcatca
    11521 aacccctctt tcagacaagt gatcatgtca atttctccgt caccatatcg gcaaacggaa
    11581 cattcgtgtt taacgatata gtcgatggtt tcctcagcca taaggatatt gaaagcattc
    11641 cttttccgct tcaacaaatt atattgaagc caatacaccg cttttcgcaa aggcactttg
    11701 atacccagcc aaaatgaatt caatacggaa gtcatagtat tgtttaataa taatcctttc
    11761 ttacaaaaaa acgttcgttg atattcctga gcagaagcac gaaccatcta gctgtcccgc
    11821 atatgtttct atactcctta ttccgataga ctttcatgaa atccttaaaa ttagtacggc
    11881 aagtagtcca gtttatccat tctagctgct tatatttcaa tcccattaga atattttgca
    11941 taaaagcttt ttcttgctcg tttttacatt ctattctttt caaataggtc ttcatccaat
    12001 cagcatataa gaaacaagct ttcagtttta gaagcattct gtcagaagtc tctttgtttg
    12061 aagaaatatt gatgccagag aaacgaaaca taaacaaagg ttgcatactg caagctacac
    12121 cgtttcccga taacttactc caagttgcat catcggtaaa gaaagccaaa ggaaaagcga
    12181 caaagccccc cgttgagatc atagcttttc gtctaaacat aaattcttgt acagtttgga
    12241 gccgatggtt gcacaaacgc tgggaaataa aatccaaaca gctttcaaat tctgctgaag
    12301 gtgcagacgt accgattacc cccccaaaaa aaaatgttaa ttttattaac acgacaatga
    12361 aataagtcgt attgggaata tttctcggta agtttcacca tttcttccaa ataagttggc
    12421 gcatacatgt catcatccga agccattacc acccattcgc ccgatgtttt ggggagacaa
    12481 taatcattcc attgctttac caaatcttta ccgccgacat tatactcgtt ctcataatat
    12541 gccagacgtt catcctggaa tttagcaacc acttccttca cattttcggg agatgcatca
    12601 ttgactatga tcaattcaaa atctctataa gtctgtgaaa gaatcgaatg aacagcctct
    12661 ttcagacaag tagctttgta agccggtaat acaactgata cgaatggcat aattattaaa
    12721 atgattattt attcaatgat ctaaaaaaga tgtagccgat gtatttcagg gggagtaggt
    12781 acaagaacaa cttccatcct ctcgacagcc cgatgctttt agcctctttg cgtacctcct
    12841 gcaaaaaagg gtggcgtaaa ttcactcgcc cctgctgagc catgaatgcc gacttcaaag
    12901 cccttacttt ttgaaaggta aacgcttctt ttacctcttc gtagtatccg ccagtcttca
    12961 atgctgaaaa aaggcaatca cagaatcggc tctcatattc caagttggtg cggaaggtgt
    13021 gcgataccga ctctccatat acatgatacc catataccat gtcccggata acggcaattt
    13081 tctttgcctt gttg
//
