LOCUS       c00023_gnlPro..        16164 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EEEOBLMJ_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:46:49
            Original ID  :: gnl|Prokka|EEEOBLMJ_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16164
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16164
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3193:6164]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3194..6164
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16164
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16164
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             231..1226
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MNYSHFVGLDVGKKTFDASLMSADEKELSHKSFDNTPTGIQSLLD
                     WIAGYHLSLSKLLFCAENMGSYVTELSVSSVSMGFSLALVCPLTIKKSIGLQRGKNDRI
                     DAKRIANYAVLHYRKLELYKLPDKDLVRLRGWIIIRDNLVKQKVSSIKLLETFSWMAKL
                     ADVTESISFLEEQLKSIKERILEVEEDMEQLIAASTSLYTNYLLLRSIKGIGIINAIVL
                     LCVTDNFQRFDNPRKFACYCGVAPFEHTSGISIRGKTQTSSLANKEVKVYLTRAAITAI
                     SWDPQMKAYYKRKIAEGKHKASVINAVRAKIIARSFAVIRRQTPFVTLAV"
     CDS             complement(1405..2628)
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MERTTFCLLFYIRRTKLNRNGEAPIMMRITVNGVRVDASVKKTIL
                     PEFWSAAKGKALEKKREYKELNLYLDSIRLRIMKIQRELEIEEVSVSANSVLDRFLGKD
                     APVQRTLFEVFREHNDKCVQLSGTDMAPATVQRYETSLKHTRDFVWETYHKKDVLLDEV
                     SRQFIEDYEFWLKTEKKCCHNTATKYLKNFKKIIRIALAKGWMKNDPFLEIRFSLDKVE
                     PDFLEDSEIQKLISKEIDIPRLSQVRDIFVFCCFTGLAFSDIHGLRKEHIVEDSNGVRW
                     IRKGRQKTKIMCNIPLMEIPLKILEKYSTNEYCKKHGVLFPVLCNQKMNAYLKELADIC
                     GIKKTLTTHVGRHTFATFALANGVSIESVAKMLGHTNVQMTRHYARVLDRTVIREMSQI
                     KMDFHISI"
     CDS             3194..5422
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_3"
                     /sec_met_domain="Gly_radical (E-value: 1.5e-45, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTDARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLIEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             5436..6164
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.7;
                     E-value: 6.1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.8e-29, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFKLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQGKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(6157..6606)
                     /locus_tag="ctg23_5"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(6593..6760)
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDKVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(6820..7323)
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVLTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             7517..7747
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             7834..9948
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCRIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKISNRKNLSGSKQQTPPDGTPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEETSAFIK
                     SQFTDFPADETVSLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRRPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(10018..10323)
                     /locus_tag="ctg23_10"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(10304..10636)
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             10653..11069
                     /locus_tag="ctg23_12"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPTKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFDFSPHFQINPPIEADFRKYLLSL
                     MCKRSKESDMGNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(11226..11480)
                     /locus_tag="ctg23_13"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYISVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGDFK"
     CDS             complement(11498..11632)
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSEKLLELIDQKKELSSN"
     CDS             complement(11750..13108)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 152.2; E-value: 5.8e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_15"
                     /sec_met_domain="MFS_1 (E-value: 2.3e-46, bitscore: 152.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDSERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     RGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPCNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(13124..14044)
                     /locus_tag="ctg23_16"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKNDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQVPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 ttttgacaca tttacatttg cagtattaaa tatcacaaca aaatataagt gtatatttga
       61 aaagtagagt tgcagtgaac taactttgac actagtctta aatgactata ggctgaatca
      121 gactgcaact ctcttaatag gagaacctag ccagttagaa ttgtaggctc acgacctaat
      181 aaatgtatta gctgtttctc cttcatgttt aatactgtaa atacaaagtt atgaattatt
      241 ctcattttgt aggtcttgat gtaggaaaaa aaactttcga tgcatcatta atgtccgcag
      301 acgaaaaaga gttgtctcac aagtcttttg ataacactcc aactgggatc caatctttat
      361 tggattggat agctggttat catctctctt tatccaaact cttgttctgt gctgaaaaca
      421 tgggaagtta tgtcacagag ttatctgttt ccagtgtctc catgggattt tccctggctt
      481 tggtttgccc gttgaccatc aagaagtcca taggcttgca acgaggcaaa aatgaccgca
      541 ttgacgccaa aagaatagcg aactatgcgg tattacacta tcgaaaactg gagttataca
      601 aattgcctga caaagacttg gtgagactgc ggggatggat tattatacgt gacaatttgg
      661 tcaagcaaaa agtatcaagc ataaagttat tggaaacatt ctcctggatg gctaagttgg
      721 ctgatgtgac agaatccatt tcttttttgg aagagcagct caagtcgata aaagaaagaa
      781 tcctggaggt ggaagaggat atggagcaac taatagccgc cagtacatcg ctttacacaa
      841 actacttgct attaagaagt ataaaaggaa taggaattat caatgccatt gtattactgt
      901 gtgttactga caattttcaa agatttgaca acccgaggaa atttgcctgc tattgtgggg
      961 tcgccccatt tgaacatact tcaggtattt ccatacgggg aaaaacgcag acttcttcat
     1021 tggctaacaa agaagtaaaa gtatacctta cccgggcagc tattactgcc atctcttggg
     1081 atccgcagat gaaagcatac tataaaagga aaatagcaga ggggaaacat aaagcatctg
     1141 taatcaatgc tgtaagagcc aaaatcatag caaggtcttt tgctgtgata cgaaggcaga
     1201 ctccatttgt aacattagcc gtataataaa aaggtcctta acttcgaaaa tatcttaggt
     1261 ttaggaagta gctatacact tctgaagagt aggtatgtct atatacaaac ttacccaagg
     1321 atacgttaat gttcgtaaac ttgggtaaga ttttatagat attgtttgga gaggacttag
     1381 aattcaacct cctaccagat aattctaaat agagatatga aaatccatct ttatctgtga
     1441 catctcacgt atcactgtac gatccagcac acgtgcataa tgacgggtca tctggacatt
     1501 ggtatgccct aacatcttag caacgctctc tatcgagaca ccattggcca gagcaaatgt
     1561 ggcaaaagta tgacgcccaa catgggtggt caatgttttt ttaataccac aaatatcagc
     1621 cagttccttg aggtatgcat tcattttttg attacaaagc accggaaaaa gcacaccatg
     1681 tttcttacaa tattcattgg tggaatactt ttccaaaatc ttcaatggta tttccattaa
     1741 tggaatatta cacatgattt tggtcttctg tctccccttt cgtatccacc tgacaccgtt
     1801 cgagtcctcc acgatatgtt cctttctcaa accatgaata tccgagaaag ccaaaccagt
     1861 gaaacaacag aacacaaaaa tatcccgtac ctgacttaac cgtggaatat caatttcctt
     1921 cgatatcagc ttctggattt ctgaatcttc caaaaagtcc ggttccacct tatccaatga
     1981 gaatctaatt tctaaaaacg gatcgttctt catccatccc ttagccaaag caatacggat
     2041 aatcttctta aaattcttca aatatttggt ggctgtgtta tgacaacact ttttctctgt
     2101 cttaagccaa aactcgtaat cctcaataaa ctggcgggaa acttcatcca aaagaacatc
     2161 tttcttatga tatgtctccc agacaaaatc ccgggtatgc ttcaaggatg tctcataacg
     2221 ctgcacggtt gcaggcgcca tgtccgtacc ggacaattgg acacatttat cattatgctc
     2281 acggaaaacc tcaaacagag tacgttgtac gggggcatcc ttacccagga aacgatccag
     2341 aacactgttg gcagaaacgg atacctcctc tatttccagt tcacgttgaa tcttcattat
     2401 cctcaaacgg atagagtcaa gatacagatt cagttccttg tactcacgct tcttttccag
     2461 ggcctttcct tttgccgcac tccagaactc cggaagaatt gttttcttca ctgaagcatc
     2521 aacccggact ccattcactg taattctcat cattatcgga gcctcaccgt tccgattcaa
     2581 tttcgtccta cgaatgtaga acaatagaca aaatgttgtt ctttccatct tacttgtttt
     2641 ttaatcacaa aactaaattt ccaagagcaa caagtcaaga tgcaaagcac tgataaacaa
     2701 tgaattattt acttaatagg tgtacctggc attgaaggca atcaggtaca ccgaatagta
     2761 caccgaaaga atgctttgat atgcttattt ttgctatgta ccaaaaacaa aaaatccccg
     2821 taaagtatta atttacaggg attttctttg ttttgcaatt ctttccagcg gagagacagg
     2881 gattcgaacc ccgggtacct cgcggtacaa cggttttcaa gaccgccgca atcgaccact
     2941 ctgccacctc tccaaaactt ccttatcaga agtgcttttc gttaaaagcg gtgcaaaggt
     3001 acgaagatat tttaaacttg caagagtttt cactaaaaat ttaatctaat cttttcctaa
     3061 ggatagcaat taataggtat tttatgttga aaagcataaa atagagcata tttatgctga
     3121 ttatatgaaa aatgattgta actttgtgcg ctctaaagaa taggataact acaacctcta
     3181 attttatcat tttatggaat taaacaagat ctttaaagac ggtctttgga gcagcgaaat
     3241 caacgtcaga gatttcgtaa gtcataacat cactccgtat tacggagatg cttcattcct
     3301 cgaaggacct acagaacgta ccaaagccgt atggaaccgc tgcctcgaag cgttggcaga
     3361 agaaagagaa aacaacggtg tccgctcatt agataatgtt accgtatcaa ccatcacttc
     3421 ccacaaggcc ggatatatcg acaaggaaaa cgaactgatc gtcggcctgc agacagacga
     3481 acttctgaaa cgtgccatca agcctttcgg aggtatcaac gtagtcagca aagcctgtca
     3541 cgaaaacggc gtggaagtgg acgaccgcgt aaaagatatt ttcactcact accgcaagac
     3601 gcacaacgac ggagtattcg acgtatatac ggaagaaatc cgttccttcc gttcgctggg
     3661 attccttacc ggacttcccg acaactatgc acgcggacgc atcatcggtg actaccgccg
     3721 tatggctctt tacggcatcg accgtctgat cgaagcaaag aaggaagatt tgcacaacct
     3781 caccggtccg atgacagatg cccgtatccg tctgcgcgaa gaagtggcag aacagatcaa
     3841 ggcactgaaa gacatgaaag tgatgggcga atactacggt ctcgacctga gccgtcccgc
     3901 ttacacggca caagaagccg tacagtgggt atatatggct taccttgccg ccgtcaaaga
     3961 acaagacggt gccgccatgt cactgggtaa cgtttcttct ttcctcgata tctatctgga
     4021 atatgaactg agcaaaggaa ccatcaccga atcgttcgcg caagagctga tcgaccagtt
     4081 tgtcatcaaa ctgcgtatgg tccgccacct gcgtatgcaa tcatacaacg acatctttgc
     4141 aggcgacccg acctgggtaa ccgaatctct gggcggacgt ctcaacgacg gacgtaccaa
     4201 agtgacaaag acctccttcc gtttcctgca gacattgtac aacctcggcc cttcaccgga
     4261 accgaacctg accgtactct ggagcccgga acttcccgaa ggattcaaag aattctgtgc
     4321 aaaggtttct atcgacactt cttctatcca gtacgaaaac gacgacctga tgcgtgaagt
     4381 acgtcagtcc gacgactacg gaatcgcctg ctgcgtatca taccaggaaa taggcaagca
     4441 gattcagttc ttcggtgccc gttgcaacct ggccaaagcc ctgttgcttg ccatcaacgg
     4501 cggacgttgc gagaataccg gtacagtcat ggtgaagaac atccccgtac tgaccagtga
     4561 cacgctgaag ttcgaagaag taatggacaa ctacaagaaa gtactgatcg aaatcgcccg
     4621 cgtatacaac gaagcgatga acatcatcca ctatatgcac gacaagtatt attacgagaa
     4681 agcccagatg gctcttgtag atacgaaccc gcgcataaac cttgcttacg gtgtagccgg
     4741 actttccatc gcactcgatt cactgtctgc catcaaatat gcgaaagtaa ctgcccgccg
     4801 caacgatatc ggtctgacag aaggcttcga catcgaagga gaattccctt gcttcggtaa
     4861 cgacaacgac aaggtagacc accttggcgt agacctggta tacttcttca gcgaagaatt
     4921 gaagaaattg cctgtttaca agaatgcccg tcctaccctc tccttgctga ctatcacttc
     4981 caatgtgatg tacggcaaaa agaccggtgc tactcccgac ggacgtgcca aaggtgttgc
     5041 cttcgctccg ggtgccaacc cgatgcacgg acgcgacaag aatggtgcga tcgcttctct
     5101 gagctctgta gcgaaacttc gttaccgtga ctcacaggac ggtatcagca acaccttctc
     5161 tatcgttccg aaatcactgg gtgctacgga cgaagaccgt atcgagaacc tcgtaacgat
     5221 gatggacggt tacttcacca aaggtgccca ccacctgaac gtaaacgtac tgaaccgtga
     5281 tatgctatac gatgccatgg agcatccgga gaactatccg cagctgacca tccgcgtttc
     5341 cggttatgcc gtaaacttcg tgaagttgag ccgcgaacac caactggaag ttatcagccg
     5401 tagcttccac gaacgtatgt aatctattac tctatatgat gataaacgta cattcatacg
     5461 aaagtatggg aacattcgac gggccgggct tacggctcgt cgtttttctt caaggatgca
     5521 acttccgctg cctctattgc gccaatccgg atacgatagc aggaaaggga ggcacgccta
     5581 ccccaccgga agaaatcgtc cgcatggcaa tgagccagcg ccccttcttc gggaaacgag
     5641 gaggaatcac tttctctgga ggcgaaccga cgtttcaggc gaaagcactc gtcccgctgg
     5701 tccgcgaact gaaagaaaaa ggcatccatg tctgtctgga cagcaacgga ggactttgga
     5761 acgaagacgt agaagaatta ttcaagctga ccgatcttgt gttattggat ataaaggaat
     5821 tcaatcccaa ccgccatcag acgctcaccg gaagaagcaa cgagcaaacc atccgcacgg
     5881 ccgcctggct ggaagaacag ggaaaacctt tctggctgcg ttatgtgcta gtgcccggat
     5941 acagcgattt tgaagaagac atacgcgcac tgggagaagc actcggaaaa tacaagatga
     6001 tccaacgggt ggaaatactg ccttaccata cactgggcgt acataagtac gaagcgatgg
     6061 gacaggaata caagatgaaa ggggtaaaag aaaatacccc cgaacagctt gaaaaagctg
     6121 cggaggtatt caaagagtat ttcactacgg tagtagttaa ttaatggaga attctccaat
     6181 gacctcaaag caagggcatt ctttaatccg ttcccaagga tctacgatcc cattatagtt
     6241 ggtgtcggga cttaaatccc gatgccctac tactttagct tccggataac gctgcaacaa
     6301 ttcgtgtacc aagcgatgta gcgcctcctt ctgacggggt gtacgcgtat ccgccgcttt
     6361 tccattctca tccagaccgc cctcatagca tacacctaag ctgatcgcat tgtagccacg
     6421 tgcatgagct ccgaccgtat cttcatcccg catcggctca atctcgcccg acttgcgtat
     6481 ataataatga tacccccagc acgaaaagcc acgataacgg tgagccgtat ccacatcctt
     6541 tgccgtaaag tcgcaatcga cacgggtggc ggaacaatgg atcacaatca gactaatctt
     6601 tctcatgttc cttttccctt tccgtcgttt tcactttgca cacctcctta caagtagtat
     6661 gatagcgcac ttctctcacc accttgtccc gctttctctt tccgaagaaa ggaatcagat
     6721 acatgatcac atctaaaatc cggtttacta tttctttcat cttatcaaaa tattaatgga
     6781 agttattcta attcgttatt accttgaccc gtctgccaat tataccgtag ggtccggagc
     6841 ctcttcatca ccggagccat caccaccgga atccggattc ttgtcagggt cttctccccc
     6901 gccatcgcct gcacccgcct gcgccaccgc acgagtcagc acttgctggt aactcagaat
     6961 cttcatcaat tccgccagcg ttttaccggg gcggaaaata agatgcgccc ccttaatcat
     7021 cgaaccggaa aattccttga ccgatgccgc accttcactg ttcagtccta tctgcaaact
     7081 gcccaaatca cccagtctcg caattcttcc tgccttcaac gcacgcttca cttcgtaaag
     7141 aatacccgaa atagccgcac gtacatccgt ttccgtacaa gtagaacgac tggtgatcgc
     7201 ttcgcacaac tcttcaaagt ccagctcacc cgacgcctgc gcctgtgcat aatactttgc
     7261 cggttcactc ttttttgcag gattcttgcg cggcaccact gaataagata ctgtcattgc
     7321 cataataaaa taattttaaa gtttataata cgtaggatgc atccctttct tgttaacagc
     7381 acaaagataa ggatagccgg acaagccata ttccccaacg aagtttcttg attcccaacg
     7441 aataaaaatg aagtcaaacc tttgaaaaac aaggaatttt atgtaacttt atagcataaa
     7501 acaagaagaa aacatcatga attacaaaga agattctttc cttatccgca cctataccaa
     7561 agcggaactg gctcaccttt acaatcccca tgtctgcctc aaagttgctt tacaaatact
     7621 tcgtcgttgg attatttaca acctccctct cctgcacgaa ctcgaacagg aaggctaccg
     7681 cgcacgcaac cgtctccttt cgccgaaaca agtggcaact atcatacact ttttgggcga
     7741 accgtagtaa cttattgcca ttttatacaa agttccttta cacatttccg caaagaagtt
     7801 cctttgcatc gacaaacaat aatcaaaata aaaatgaaac atttcaccat atttcaaggt
     7861 ttctactacg caatagcaga gatgaccgaa gaagaaatag tgtccactat cggcagtttt
     7921 acctaccggg aaaaagtcga agaaatacgc cgcatctttg cagagcaagg agaaaaggct
     7981 gccaatgaga agaaaaaaga attgccggca atcgccttct ccgccagcta ccgaggaagg
     8041 cgtaccaaag tgaacctcgt caaatatctg ggacacatcg tgatagacat cgaccacctc
     8101 agcaaagaag aattggcacg catcctccct atcatcaaga gatgcgatta cacccgcatc
     8161 gcctttatca gtcccaaagg gatgggcgtg aaaatcatag tgcgcgcatg ccatccggat
     8221 gagacattgc ccgaaaccct tcaggaaata gaagacttcc atcatgcagc ttacaccaga
     8281 ctcgtttctt tttacaccga actctgtcgg atagaaatcg acacctccgg tcaggatgtg
     8341 gcacgcactt gtctgttctc ttacgatccg gagatctatt tcaatccgaa cgctgacgct
     8401 tttcttgtag atcaacctca ggcatcctac aagatttcaa atcgtaaaaa tctctccggc
     8461 agtaaacaac agactcctcc ggacggcacc ccgacgaatg aagacacagc actcaacgcc
     8521 cattccgcca acgcttcttt ggtgttgact ttaacttact atcacaacaa gtccgaaaaa
     8581 tacatagcag gcaaccggaa caattatctg caccatctct catgtacctt caatcgctac
     8641 ggcattccgc aggaggaaac atccgccttt atcaaaagcc agtttacaga ctttccggcg
     8701 gacgagacag tctctttgat caatagcgcc tacgctcata ccgacgaatt taatacctgt
     8761 aaactgaatg gcacgcagaa acgaatatta cggatagaac aatatatcag cgagcactac
     8821 gaaacacgct acaatgaagt gctgcatatc atggaatatc gcagaaggcg tcccgacacc
     8881 gagaaaccgg agcctttccg catcttggat gagatgatgg aaaacagtat ctggatagaa
     8941 atcaacgagc tgggatatcc ctgcactgtc aaaacaatcg aaaatctgat ttactccgat
     9001 ttcagccagt cgtatcatcc cattcgcgag tattttgaat tactgcccga atgggacgga
     9061 accgactata tccgtatcct ggcggatagt gtccagacga gtcatcagga gttttgggcg
     9121 gaatgcctgg aacgttatct ggtggcgatg tgcgcagcgg ctactcagga gaatattgtc
     9181 aatcacacgg tacttctgct atgcagcgag atacagaaca taggaaagac tacctttatc
     9241 aataatctcc tgcctcccga actgcgtgct tatctctcta ccggactaat caattcgaac
     9301 aataaagatg atttagccaa aataacgcag gccatgctga tcaatctcga cgagtttgaa
     9361 gggatgagcg gtcgggaact gaatgcattc aaagatttgg taacgcgcaa agtgatcagt
     9421 ttccgtctgc catatgcacg ccgttcgcaa aacttccctc atacggcctc ttttgcagga
     9481 acctgcaatt atcaggaagt gcttcacgac acgacaggca accggcgttt cctttgtttt
     9541 catccttatt ccatccaatt tattaccatc aattatgcgc agctctatgc tcagatcaaa
     9601 tatctgctga ataagccggg gtaccaatac tggttcacgc aagcggacaa tgaacggctt
     9661 gaagagaata acgaggcttt catctttcat tcaccggaag aagaaatggt tcttacgcat
     9721 atccgcaagc cggaacgttt tgagaaggtt tattatctga ctgtcagtga gattgcggaa
     9781 ctaatacgtg agcgtaccgg ttatcagtat tccatcggat caaaaataca gttggggaag
     9841 gtgatgacta agcaccattt tgaatctaaa aaaggaaata acgggcgccg atatgccgta
     9901 tttattatag atatcgagca ggtaaaatca aacaggctgt atgaatagaa gcgggaaagc
     9961 cttgtgaata tagcaaaatg cagagtcatc ttgacagata ctctgcattt attgttttta
    10021 caaaatcatt gaaaattcga ttttacagcc taacgcattc attatacgat agaaagtaga
    10081 tactttaggc tctgtctgac cactttctac tcttgaaata taagaacggt cagagccgat
    10141 acgccgggct aattcagcct gagtgatttt agcctttttt cttgcgtcct cgataatctg
    10201 tcctgtataa aaggcgtagg ccttttcttc tgcctctgca cgagaagctg ttccttcctt
    10261 accaaaacgc tcatctatta atgcactgac attaaagaat tcctcatttg tttttgcttc
    10321 cataatactc ctttcttaat atctttgctt tatcaatttc tttctttggt gttttttcgg
    10381 ttttcttttg aaaaccgtta aacagaatca caatacgccc ttcgtcgaaa caaaagaata
    10441 ttctatatat attgctttgg tactcgatac gaagttcata aagtccttct tctatcaacc
    10501 gcataaattt caaaggtatt ctgtcttgtg tctgcaataa cattagcaca tacaatatct
    10561 tatcttgggt gccagcatct aaattttcaa agaattcttt gaagtatcct ttatatgcta
    10621 ttatttctct tttcataacg caaatataag aaatgttgtt caactataca acacatttcc
    10681 tcgttttata ttatttttca tcatcttcac ccacaaaagt gagaggagtg agagaggaat
    10741 tgaaactttt tctattttat ttctttattt ctactttcta tatttctcta aaaaaaatac
    10801 gaatgttaga aatcctctct cactcctctc actttttacc ttttctttct ccaaaaagac
    10861 ggcgggaaat cggaaaaaca caaccgtctt ttttcgattt ctcaccgcat tttcaaatca
    10921 acccaccaat tgaagcagac ttcaggaaat atttgttatc tttgatgtgc aaaagatcaa
    10981 aagaatcaga tatgggcaac ttgatgcgta aacttcctat tggaatacaa acctttgaag
    11041 atatacgaag gaagaatatc ttattgtaaa gatcggagtg gaatttagtt cagaaagccg
    11101 gaacttaaac cgttggttaa tagagactat tgagtaatag aaacccaagt ggcggcaatc
    11161 tgcaacaagt ttccatccag atttccgcca cttttttaat tcaaccgttc agcgatggaa
    11221 acagattatt taaaatctcc ctccgaataa tctgaaaact ccccggcacg ttctttcttc
    11281 tcatacgaga ccaacgtttc gatactaagc gctttcccgt tcttagggct tatgacatct
    11341 atcacacttg acaaggaccg gaacgtctgt tcgcaattcg cgtctccatt atacgtcaac
    11401 ctcccccggt caatagcacc tagaatgaca gaaatgtacc gtttcggatc tccccgatat
    11461 tcgataacag tgggcgtcat ttgttcttct tcccgaatca gttggacgac aattcttttt
    11521 tttggtcaat cagctccaac agtttttcac tatgcacact gatttgtgca tctacttcac
    11581 gaagttcatt cttcaatgaa caaaacaatt catcactcaa tgaattttcc ataaaaacga
    11641 tttttattaa ttataaaaaa gccattccgg aaagcacagc tattgcctgc ttcccgaaat
    11701 ggtgactaat accttcaaaa acaatgactc tatttttact ttaatgtact caatttattt
    11761 cacttctttt ctctcctgca ttccaaacca acaaagcaaa cactactgaa agcaaggctg
    11821 caccaatcca aaaccaattg atatatgtaa aatcgtaaac ttctactcca ttttgcaccg
    11881 tcttctgacc ttcgatcaga atgccactca tcacatcctg caaaccggct cctatataac
    11941 tcgctatacc gacaactccc aaagcggctc ccgaagcatt gcagggagca atatcgaccg
    12001 ccatcagtcc tcctaaaaaa caaatcagca ctccaatgcc caaaccgaag agcaccatcg
    12061 ccaaagcatc cacccaaaaa tgtacccccg gaaccaatag aaacaaacaa agagcagaca
    12121 cattcattaa tccgaatatc aaagccggaa cattacgact gccagcaaaa aacttatctg
    12181 aaataatacc tgagaaaacc gtacctacaa ttccgcatac agaactgata gatataataa
    12241 aactagcatc caaagtagaa taaccttttt gcgcttccag atagaaaaca ccccagctat
    12301 tgactgcata acggctgata tacataaaag cactggataa tgcaagaatc caaatagcag
    12361 gattcttcaa aactgctttc tgagctttat tgaattcctc ggtttgttta ccggaaacgg
    12421 aatgagcatc tgacgtcccc cgccgatcta gcaaaaagcc ctgactttga ggcgtatcac
    12481 gcataaaagc aagcatcatc agaaaaccaa gcaaaccaat cactcccgca ccgatcatcc
    12541 cataacgcca tcccatccaa ctgaccagca aagcgatgga tataaaagtc agagcttcac
    12601 ccaaattgtg gctggccgac caaaagccat aaaaagtacc tcgctcttta ctactatacc
    12661 aacgagtcag cgacacaact cctgatgctg cccccatcga ctgaaaccaa ccattcaacc
    12721 cccaaaggag aacaaaagca aagaaggaat tcgtgaatcc cagacataag ttgatcagag
    12781 cagaacacaa taatccggta gacataaaac gctttacatt gctacggtca gcaagaaagc
    12841 cattggtcag cttaccgacg gcatatacga aaaaaaggca ggaaccgata atccccagtt
    12901 gggtttcggt aaaaactccg tcttctacaa tcggtttacg gattacattc atactcaaac
    12961 gacaaacata ataaatgcca tatccggtag tggcagacag aaaggtagcc caacgaatac
    13021 gcttgaaacg gacagagcgt tccgaatcag tctctccccc ggacaccgga ggagagattt
    13081 tataaaaatc caatagttta aatcccataa agaagtctat attttaatga tacgcatctt
    13141 gcccgttttc actacgcttc ttacgcgatt gcaaatattc cagcagatag gcagtacggt
    13201 ctgtctgaat gatggccgct ccgagtgtat cgatcagata accatatcct tcgtccggat
    13261 tctccaacga tttatcatca tcatgtccgc cagccatcgt atcccacaac gtattatacc
    13321 agattttact ttttcctttc aacttcgttt ttacttgctt ggggacctgg caggtatccg
    13381 atacaaatag aagttcaaaa gctacgggat gcagctccgt cataaaatca tccagttgct
    13441 tcattgctcc cggcttatcc aaatgaatga taggcatata aatgatacgg tccagatatt
    13501 tacctaagtc gttctttacg tctgccacag gcttggaacc tttcatgata atctgatcca
    13561 ctgttcccgt cttttcgagg atggggaaaa tctcgtcaaa tatcggatat gctttatcca
    13621 gattgaccat cacacgacct ttggcaaccc ataaagcctc ttccaaagta ggtacacgat
    13681 gcttggtttt gagtgccgct ccattcttca gatagagtgt ccggatagaa tccaatgtcc
    13741 attcggctac ctttcctttt ccggtagtcg ttcggtccag cgttttgtca tgcatcagga
    13801 tcaattgacc gtctttggtt ttctgaacat ccagctccac tacgtcagct cccagacgaa
    13861 tggaactttc aatagcggca agtgaatttt cgggtgcgta acgccagtct gcccgatgag
    13921 ctacaaccgt gatttcttta ttgtcagggt tcgttatctt cgcataaatg gctttcaccg
    13981 gttcgtctgc cgacaggcag aaaggaaatg cgaataagat tcctatcatt atatatttct
    14041 tcatatctat atgtactatt atctgtatcc tttagacttt aaatatttgg cagctacttc
    14101 agcatagtct gtttgcacaa tgttgatgcg tttgttaatc attcccacca aaccggagta
    14161 gttttccgac aacatattgg tatcattcgc tccgacaatg ttggagaaaa gaagccagcc
    14221 ttgatcttta atctcattaa ccatcgttcc acccatagcg tctgacgtag acagctgcat
    14281 catttgtaca ttatcagtgt aggatgagga gaagtatgtg atatcatcgg cggcttttgc
    14341 catcgggtgc aacagcaaac tactgttggc tgtcttcaaa tcaaatgcat aattgcgatt
    14401 gttggataca tacagcaaag tggaaccttc catatccaat tttttaagca atgcgacgat
    14461 cgtatttacc gcaacattct tgttgacaat atccagatta taataaactt ttccttttcc
    14521 cttcttcatc gcttcctcca aagtcgggat tcgttcgcca gttatattgc cggatgcatc
    14581 tttcagataa aattgttgta attgctgata agtaaagtct cccaccgcac cgctaccgtt
    14641 tgttgtccgg tcgatggtgt tgtcgtgcat caataccaac acaccgtcag aggtcggccg
    14701 tgcatccagt tcgatcatct caactcctgc tttgaccgag tgttctatcg caggtaacga
    14761 gttttcggga atcccctctt tcatcccttt ttgggtattt ccacgatgcg cgcagagcca
    14821 cactttataa gaggtgcttt caaacagact ctttaaatct gctttcaaat tccccgtcat
    14881 aggcaactgt cctccttctt ctccaccggg attctctcca ttccctcccg attgggctcc
    14941 ggagtgacgt ctgtccttcc ctttcatcgg ccaggcagag gttgcggccc cggtaattcc
    15001 ctcatcttcc aaagctacta acacgctctt tgtagggtcc accgtattgg tgactccgat
    15061 ataaatcgct ccatccggtc cgatggtagg cgaactccag attttaccga ttcccgcttc
    15121 ccaatctcct tttaaaggag agtcactttc actaatcaac gcagcaaggt cttttttcag
    15181 aatcaattgt tcatccgatt cttccggttt aatgatataa taattgccgg actgggtgcc
    15241 gaaatgtatg tttcctgctt gatcaattgc cgcacaaccg cttacatctt ccgcaatgcc
    15301 gtaatgccat tggatagctc ctcccggaga caaagagatg attcctccgg ttgcttcccc
    15361 cggagcacgt ttcactgtaa cgataatgct tccgtcgagt cctatcacaa caccgccttg
    15421 atccagcgtg ccgacattgc ccaaaggagt acgccacttc tccactccat cacttcccat
    15481 agcaaatgcg ctacttccca ttcctgcaaa cgtagctgtt ccgtaaatag taccagcctc
    15541 atctactgcc ggagaaccgt tcatattttc tgacggctta tcatcgccgg agctaaatac
    15601 ctgccaagcc cacattacat ttccaccggc attcaacgca gaagcagaag ccccgaacaa
    15661 tccattcttt ccgccacccc aaactaaagt gttgtttgcc aatactattc cggcagatac
    15721 tcctccggaa ggacctccgg aattatccgc attcgctacg tatcctaccc gatagccggt
    15781 caccttatct actgcaagca ctgatcctgt agaaccgcca ttacccatat atacatgatt
    15841 ctcaccaatg gcacaggtca ggtaattgat acggggtgtg gaagcgtttc ctttattcca
    15901 gaagcccttt tcagcgtcac ctgccaccag ccatttctta ctcccgtccg gatttattgc
    15961 atacacacgt cctactttgc cactggtgtc tcctgttcct acgtagattg ttccgtctat
    16021 atcaatgctt ggagtagtat gcgtatttcc ggatggtgca tcgccgtcag cagatgtcca
    16081 aaggtcaaat tcccaaagct ggtctcctgt cgctgccgaa aatttacgta aataatgatc
    16141 attggaagtc atatacaccc catt
//
