LOCUS       c00036_gnlPro..        15377 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PIPAHMHK_40.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:25:39
            Original ID  :: gnl|Prokka|PIPAHMHK_40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15377
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15377
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2421:5377]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2422..5377
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15377
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15377
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             282..1040
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="MKRHNYNIAIAITISCILFFINGYHNYIKDKRKDNLEKYKAGYYD
                     NVTVKNKNIEPSTTKNYVPPKNWTKYIIANAFSISVPPTVELRKSNDSYTKDIKNLNWH
                     GHKINSNNVVFQQKGLSVNTPEAHQTYCRIIIDIQKGSLGEYPKFSDYEDLTIEDIHTF
                     QELAKQNSYEYKILGQPEVRWIKIEDTYGIEVEYVRNGANNSRTHVCNYYFFNDNLFAT
                     IILSYRQDDIRKWETDFSNIIKTFKWNNKK"
     CDS             1044..1703
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="MEKISFMRRLSSSLIDKVLILVLFIISALCISPYGMASHLGSYYA
                     LLDAVPSSYPAQDTYKAMHSVYDNTIYESTEKWVQCYKEISQKPELIAPHKGETLSWDL
                     QITGLFIIVNFIYYLLWEWIFRASLGKFLCGLTVASDNNQPTTEKEIIKRCFLLLLLMI
                     AAVGLRFTFDINYYMTILLFFLIVDTSVIIKGKSLIDIMTNTYITKRKIYKNENLK"
     CDS             2422..4650
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="Gly_radical (E-value: 9.7e-46, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1169.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTDPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4652..5377
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 75.5;
                     E-value: 1.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="Radical_SAM (E-value: 2.6e-30, bitscore:
                     99.5, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCPFRCLYCANPDTIDVKGG
                     TPTTPEEILQMAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICLDSNG
                     GIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFWLRYV
                     LVPGYSDSEEDTRLLGESLGKYQQIQRVEILPYHRLGVHKYEAMGWDYKLKEVKENTPE
                     QLERAEKLFKEYFTNVITN"
     CDS             complement(5446..7650)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 84.6; E-value: 1.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg36_5"
                     /sec_met_domain="Fn3-like (E-value: 3.6e-26, bitscore:
                     84.6, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 6.4e-74, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 1.3e-51,
                     bitscore: 168.9, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRNKVVTLYDALVRKGLEVSYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALKQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKAAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNVGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(7681..10143)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.1; E-value: 3.4e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="Fn3-like (E-value: 9.6e-25, bitscore:
                     80.1, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 1e-55, bitscore:
                     182.8, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 6.5e-50,
                     bitscore: 163.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQVEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGILSASTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             complement(10320..11633)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     MIPFRRWAVAAAAVLLVAVSSVSLWLLQSPVGNEMRHTSVPALAVAPDVLPEQTVPAIR
                     TNSIEPAYRAHGNASAPNKEASHPLVAQHIRISVGEEQQEEMLPVETADEVVGIGQQAE
                     EPVVEDTDHETTMQTEEPETREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVGNTGG
                     FSLANEGEANVMSDYMPGSPIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREKK
                     IADIDHKQPLSFGVSVRKNLAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIPV
                     RANWNFVDAKNFTMYVSAGGAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRVG
                     LYVEPGVSYFFDDGSSIQTIRKENPCNFTLQAGIRLTY"
     CDS             complement(11646..12194)
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             12375..13079
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MKKLRMTLATSMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVTDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
ORIGIN
        1 taaccccatc ggtcaagact ttttaagggg gcattgttga atgttttaag ggggcagaat
       61 cgcttggttt tagggggcag cttacactgg attttccacc attacccaaa ggttataata
      121 gacttctcat tgtttttgct tgtcttatta ttgtttatac cgtacatgaa tatcctgaaa
      181 aggttaacac ttttttcttc acgctgctag ttgagattat tacttatata gctactatat
      241 ggatttatcg tggatttaaa gaattaccct aaaataaaaa tatgaaaaga cataattata
      301 atattgcaat agctatcaca attagttgta ttcttttttt tattaatggt taccataact
      361 atataaaaga taaaagaaaa gataacttag aaaaatataa agccggatac tatgacaatg
      421 taacggtcaa aaacaaaaat atagaaccta gtacaacaaa aaactatgtt cctcccaaga
      481 attggactaa atacataata gcaaatgctt tttctattag tgtacctcct actgttgaac
      541 taagaaaaag taatgattca tacactaaag atattaaaaa tctgaattgg catggacaca
      601 aaataaatag caataatgtt gtttttcaac agaaagggtt atctgttaat acccccgaag
      661 cgcatcaaac atattgccga attataatag atatccaaaa aggaagtcta ggagaatacc
      721 ctaaattttc agattacgaa gatttgacta tagaagacat ccatacattt caagaactag
      781 caaaacagaa ctcttatgaa tataaaattt taggtcaacc agaagtgcgc tggattaaga
      841 ttgaagatac ttacggaata gaagttgaat atgtgcgaaa tggagcaaac aattcccgta
      901 ctcacgtctg caattattat ttctttaatg acaatctatt tgcaacaata atattatcat
      961 atagacaaga tgatataaga aaatgggaaa cagatttttc aaatataatt aaaacattta
     1021 agtggaataa taaaaaatga gttatggaaa aaattagttt tatgcgaaga ttatcaagtt
     1081 ctttaataga caaagtctta atcctggtat tatttattat tagtgcttta tgtatatctc
     1141 cctacggaat ggcttctcat ttaggaagtt attacgccct attagatgca gtcccatcat
     1201 cttatcccgc tcaggataca tataaagcaa tgcatagtgt ttatgacaat actatttatg
     1261 aaagtacaga aaaatgggtt caatgttata aagaaatatc acagaagcct gaattaatag
     1321 ctccacataa gggtgaaacc ctatcttggg atttacaaat aacggggctt tttataattg
     1381 taaattttat atattatctt ttatgggaat ggatatttcg cgcatcacta ggcaaatttc
     1441 tatgtggact tactgttgct tccgataata atcaaccaac aacagaaaaa gaaattatca
     1501 aacgctgttt cttattacta ctcttaatga tagccgcagt aggtctaaga tttactttcg
     1561 acatcaatta ttacatgact attttattgt ttttcctgat tgtagacaca tctgtaatca
     1621 taaaagggaa atcattaatt gatattatga ctaacacata tatcacaaaa agaaaaatct
     1681 ataaaaacga aaatcttaaa taaaacaaaa cacccagttt tacattatag ggtgtaaaac
     1741 tgggtgtaaa tcttataaac cgctaattat caaggtttat tgcggagaga cagggattcg
     1801 aaccccgggt gcctcgcagc acaacggttt tcaagaccgc cgcaatcgac cactctgcca
     1861 cctctccaaa acttcttttt cagaagtgct tttcttttaa agcggtgcaa agatacaaat
     1921 cattttttat tctacaaact tttctgcaca aaaacagagc aattatacca aaattcttgt
     1981 ttatacccac tacggaacga acataacggc atttaggcta tttgttgaaa tttatcaagg
     2041 gcaagacaga gttttataac ttactggcta tcagtatatt tacaaagagc cacattcagt
     2101 atacgattga accctattca gtatacgact gaatggcatt cactatacga ctgaattagg
     2161 ttcagaatac gactgttcct taaacctaca tcatttgtaa ataatgcaga ttattattcg
     2221 gttcttgttt caattcataa accacatata aagaaagtat taacatctct actcccccgg
     2281 acattcacta cctaataata gttattttat gctgttcaac ataaaaagag aagtatctct
     2341 tataaaatta cggaatttat tcagtatttt tgcgcgctct aaaggataac attatctaac
     2401 ctactaacaa aaacaaattt tatggaattg aacaaaacct ttaccaatgg gctttggaat
     2461 aaagaaatca atgtcagtga tttcgtcagt aaaaacatcg caccctatac cggggatgca
     2521 tctttcttgc agggacctac cgaacgtacc aaacgtatct gggacatctg tctgaaggct
     2581 ctcgaagaag aaaggaacaa caatggcgtc cgttcactgg acaataccac cgtatctacc
     2641 atcacttctc ataaagccgg gtatattgat aaggacaatg aacttattgt cggtttgcag
     2701 actgatgaac tgttgaaacg atccatcaaa cctttcggag gcatcaacgt ggtagcaaaa
     2761 gcatgccgtg aaaacggagt ggaagtggac gataaagtaa aagacatctt cacccattac
     2821 cgcaaaacac ataacgacgg cgtattcgat gtatataccg aagaaatccg ttccttccgc
     2881 tcactgggat tccttaccgg attgcccgac aactatgccc gcggacgtat catcggcgac
     2941 taccgccgat tggctctcta cggcatcgac cgtctgattg aagccaagca ggaggacttg
     3001 cgcaacctca ccggcccgat gaccgaagca cgcatccgtc tacgcgaaga agtggcagaa
     3061 caaatcaaag ctttgaagga catcaaggtt atgggcgaat attacggact cgacctcagc
     3121 catccggcta catcagctca agaggccgtg caatgggtat acatggcata tcttgctgcc
     3181 atcaaagagc aggacggagc agccatgtca ctgggtaacg tatcttcgtt cctcgatata
     3241 ttcattgaat acgatctggc tcacggaaaa atcaatgaga cgtttgcaca ggaactgata
     3301 gaccagttcg tcatcaagct gcgcatggta cgccatctgc gtatgcaatc atacaatgat
     3361 atctttgccg gtgacccgac ttgggtgacc gaagccatcg gaggacgctt caatgacgga
     3421 cgcgtgaagg tcaccaagac ttctttccgc tttttgcaga cgctatacaa cctcggtcct
     3481 tctccggaac cgaacttgac cgtattgtgg agtcccgaac tgccggaagg cttcaaggat
     3541 ttctgcgcca aagtttctgt agataccagc tccatccagt acgaaaacga caacctgatg
     3601 cgtgaagtgc gcaactgcga cgactacggc atcgcctgct gtgtatccta ccaagccatc
     3661 ggcaaacaaa tccagttctt cggcgcacgt gccaaccttg ccaaggccct gctgctcgcc
     3721 atcaacggtg gacgttgcga aaataccgga actgtcatgg tgaaaggtat tcccgtattg
     3781 accggtgaga cattgaagtt tgaggaagtt atggccaact acaagaaggt actgactgaa
     3841 atagcccgtg tctacaacga ggccatgaat atcatccact acatgcatga taagtattat
     3901 tatgagaaag cccagatggc attcatcgat accgacccac gcatcaatct ggcatacggt
     3961 gttgccggcc tttccatcgc catagactca ctgtccgcca tcaaatatgc caaagtcact
     4021 gcacgccgca acgaaatcgg cctgaccgaa ggtttcgaca ctgaaggttc attcccctgc
     4081 ttcggcaata atgacgaccg tgtggaccac ctgggagtag acctcgttta ctatttcagc
     4141 gaagaactga aaaagctgcc tgtctacaag aatgcccgtc ccaccctttc cttgctgact
     4201 atcacctcca acgtgatgta cggcaagaag accggtgcca ctccggacgg acgcgccaaa
     4261 ggtgttgcct ttgctccggg tgccaaccca atgcacggac gtgacaagaa cggtgccatc
     4321 gcttccttga gctccgtagc caaattgcgc taccgcgact cgcaggacgg catcagcaat
     4381 acgttctcca ttgttcccaa atcactgggc ccgacaccgg aagaacgtgt agagaacctg
     4441 gtaaccatga tggacggcta cttcaccaaa ggtgcccacc atttgaacgt aaacgtactg
     4501 aaccgcgaaa tgctggaaga tgccatggaa catcctgaaa agtatccgca actcaccatc
     4561 cgcgtttccg gctatgccgt gaacttcgtg aagttgagcc gcgagcatca gttggaagtc
     4621 atcagccgtt cattccacga aagaatgtaa tatgataaat gtacactcct acgaaagtat
     4681 gggaacattc gacgggccgg gtctccggct cgtcgttttc ctgcaaggat gtccgttccg
     4741 ttgtctgtat tgtgccaatc cggatacgat tgatgtaaaa ggaggcactc ccaccactcc
     4801 ggaagagatt ctgcaaatgg ctatcagcca aaaggcattc ttcgggaaga aaggaggtat
     4861 tactttctcc ggcggtgagc ctaccctgca agcagaagcg ctgattcctc ttttcaagga
     4921 gctgaaggcg aacggcatcc atatctgtct ggacagtaac ggaggcatct ggaatgaaaa
     4981 ggtggaagag ctctttagcc tgactgacct cgtgctgctg gacatcaagc aattcaatcc
     5041 cgaacgccac cgtacgctga cgggacgaag caacgaacag acactccgca ccgctgcctg
     5101 gctcgaagaa catgaacacc ccttctggct gcgctatgta ctggtccccg gttacagcga
     5161 ttcggaagaa gacacccgcc tgctgggtga aagtcttggc aaataccagc agatacaacg
     5221 ggtggaaata cttccttatc accgtctggg tgttcacaaa tacgaagcca tgggatggga
     5281 ttacaaattg aaagaagtga aggaaaatac tccggaacaa ctggaacggg cagaaaaact
     5341 gttcaaagag tatttcacga atgtgataac caactaaaac agaaaagcaa ggctgtccgg
     5401 atatgattcc agacagcctt gcttttcatt tatagggtaa gaatcctatt ctttcaagtt
     5461 ataggtaatc tgctgtacat catcactact gccacccacc ataaagacga aatcaccagg
     5521 ttctaccata taattcatct cattgtcata gaatcccagt gcatcgtcag ttatctgaaa
     5581 agctacagtt ttgctttcac ccacattcag atgaattttc ctgaagccct tcaattcctt
     5641 tatcggacgc gtaacagagg ctaccttatc ctgcacatac aattgaacta cttcctctcc
     5701 tgcacactta ccggtattag tcacttttac cgacacctcc gtatggacgc ctgcagcctt
     5761 gcccggcagc agtttcaaat cagaatatcc aaaatccgtg tacgaaagcc catatccgaa
     5821 aggataggca ggctcagtgg aagcatcgat ataagatgcc ttataggtct gtttcaatgc
     5881 ggtagggcgg ccggtgctct tattctgata ataaatggga atctgtccta cgtgtgcagg
     5941 aaatgtcatg ggcaatttag ccgaaggatt atactctccc cacaacacat tgcatatggc
     6001 attgccggcc tcacttccca gccaccaagt acacagtacc gcatcagcat gttcccttat
     6061 ctcattgaag attaccggac gcccacacat gacaagagca atgacaggtt ttccagtctt
     6121 tgccagttcc gacaccagct tctgctgccc ctcgggtatg gctatattca ctttggaagc
     6181 cttctcgcca ctctgaccga atctctcgcc taccgccaca acaatgacat ccgaagcctc
     6241 agcagcctgt aatgcttcct gcaatccggt caactgattg ctcttcatat catagccttc
     6301 agcatagctc acctccagtc ctttccggac caatgcatca tataaggtca ccactttgtt
     6361 ccggtccgta gtggcagccc aagcacctgc catatcgtac tgggattttg agagtcctcc
     6421 tatcaaggct atcttcctcg tctgtgccgt caacggaagc acagattccc tattctccag
     6481 caatacaacg gaacgctcgg ccatacggag cgaagcatta cggacttcgg gcgcattgag
     6541 tattctggcc gctctttccg gattacagta gcgaaaaggg tcctcaaaca atcccaactc
     6601 atatttcttc tccaatatac gccgtactgc atcatcaagc acactctcct ttactttccc
     6661 ttcttgaaca agctccttca gataagtcaa gtagcaggta cttaccatct ccatgtccag
     6721 accagcattc agcgctttgg ctgcggcatc tttcttgtca acagcataac ggtggttcac
     6781 caattcctct accgaattat aatcggacac aacaaatccc ttaaatcccc actgctctct
     6841 caatagccgg ttgagcaaga aatcattggc agtacaagga atattattaa aatcattgaa
     6901 agcactcatc acggtagctg ctcctacctt tatggccgcc ttatagggag gcatataaaa
     6961 attggcaaag tggcccattg acatatccac actattatac tcctttcctg ctatcggtgc
     7021 accatatccg gcaaaatgtt tcatacatgc catgacagtc gtcgtgtctg ccaaatcgtc
     7081 tccttgcaag cctctgacac gcgcctccgc tacccgagaa ccataataag ggtcctcacc
     7141 ggccccttcc atgacgcgtc cccaacgtgc gtcccacgaa atatccacca tcggggcaaa
     7201 aacccagttc aaaccatcag cggcactttc caaagcattg tagcgtgcag cttcctcaat
     7261 catggccaaa tcgaaacttg cagcctcggc aagcggaagc ggaaatccgg tacgatagcc
     7321 gtggataaca tccagtccga aaattaaagg aatgcgcaaa cgcgattgca aagcaagctc
     7381 ttgataacgg cgtatatcct ttactcctat cacattcagc atagagccta ttctgccttg
     7441 ccggacatac tcttctttag gaatatttcc accgtcgggt ccggtaaaat tccctcggta
     7501 ggtgcattgt gcaagctggc ctatcttttc atccagcgtc atctgcttca tcaagcttga
     7561 gatgaatttc tccttctccg tagtttgtgc cgaggtaaag gtgttaccaa gtccccacag
     7621 acaaaccatc agtattatta tctttttcat actgccattc ttgttttgat atttatttta
     7681 tcataaaaca acagttgcct tcaatggtaa atcagctgaa gaaggacctg ccagaatctc
     7741 aaaagtcccc ttttccacta caaaccgatg tgattccaca tcatagtagg caaaggcttc
     7801 ctcatccagc aatatccgaa cgcgcttggt ttcacccttc ttcaagtaaa ccttatcgta
     7861 gcctttcaac tccttcaatg gacgcggaac agaacattcc acatcccgca catatacctg
     7921 agccgcttcc gcagcatcca tctttccggt attcttgatg tcaaagctta ccgtaacccg
     7981 gcttcccccc gtcttctcaa cactcagatt actatattca aaactactgt atgacagtcc
     8041 atacccgaaa ggatagagcg gctgctttcc gttccggtca tatcccctat aacctacgaa
     8101 aacaccttcg gcatactgca cccgtttatg aggtacattg cgattgtcat aataattacc
     8161 atataccgga ttatcttccc atttttcctc gatgctgact ggtagtttgc cacttggcga
     8221 aagcttgccc gtaatgattt cggcaagggc ctttccaccc tcctgccccg gataccatgc
     8281 catcaaaata gcttgtacac tctgccccca attgcggaaa tctattccac ctccggcatt
     8341 caccaccaca gccacattat catgaagtga agccacttta ttaatgagat attcctgccc
     8401 gtatgacaat gcaaacggac ggtcgaaccc ttcaccttct gtactgctgt tgaacccggc
     8461 acatacaata acattcctgg catgcttcag tgaagaggcc aaacgctcct catccatcat
     8521 tcctgcctgg aaactgacag tcgcctcacc cacattatca aaatattcaa tacgcaaccg
     8581 gtatatctcc cctgcactga cctgcataaa tgcactgcgg gtactgaatg aatggttccc
     8641 ccaatctccg gtaatcagct tatcgtttac aaacagacgg tatccgtcat cgccagccag
     8701 ctggaacttg acagttccat ccttgtcagc cttgtaaact cccgtccaac gggcagaaaa
     8761 ctgatctacc ggcatgccgt cgaacggtgc accgtatttc caggcatggt ctatggcagg
     8821 ctctatggca gcttgaaaga gttctccggt aagattacga gtattataat attcgccctt
     8881 aaaaccgttt tgcgtaaaac tgccatccgt ataaatctgt tgggacatat ccttataaag
     8941 aatgctgtca gacagcagct ctatctgtct gccgcccttc aactgaacca taccgtcata
     9001 gagtgacact accgaataag gggtgacaaa tccgcttcct cctcctgtgg gaataatatc
     9061 ggcattaggc ccgattacca atgttctacc gttccggtaa ggcaacgtac cgttatcatt
     9121 tttcaataag actactcctt ctctcgccaa gtcaagtgca atttccttag actgtgcatt
     9181 gtctttatcg atagatttat cttctctcgg agtatcaagt gctccaaaag caatcaatgt
     9241 ctggagtata tgccggactt tggcgtcaat ggtctcttcc ttcacgatac cattctctat
     9301 tgccggaata agaatttccc tggtcatgaa tttaccgacg ggcatttcca aatccaaccc
     9361 tccattagcg gctcccacac cagaatatac agatgtccag tcagacatca ggataccttt
     9421 aaatccccac tgcttgcgta atacatcaat gttcagccag ctgttttcgg tggcatgtac
     9481 cccgttcagc ggattatagc tatccataac cgcccctact cctgcttcct gcacagcttt
     9541 tcggaacgcg ggaaaataaa tttcctgcag cgtgcgttca tccacatctg agctggcatg
     9601 atgtctgctc cactcctggt tattggccgc aaaatgcttc accgtagcca taactccctc
     9661 ttcctgcact cccaagatat attctttagc agtttcgccc gtcaaataag ggtcttcacc
     9721 aaaatactca tagtttcgcc cgcatagagg agagcggtag atattgactc caggccccaa
     9781 cagaatactt accccacggg cctttgcatc ccgggccaaa ccatgtccca gctctctagc
     9841 caacttacgg ttccatgtcg aagccgacaa gatgccacaa ggatacaagg tactttgagt
     9901 attgttacgt atgccttgcg gaccatcggc catcctgatt tcgggtatgc caagccgggg
     9961 tacagcccgg atataaaaag atttgggacc ggaaatgtaa tcgatttttt cttccagcgt
    10021 catttgagaa accaactccc tggcacgctg ctccacctgg ggagtaatac acacttgtgc
    10081 ttttgccgtg attgcacaac aaagcaatag cccgcttaag gctactttct ttttaatctt
    10141 cattttgtct attttactac gtgtttgtta tattgccggg catgtcccga cctactttct
    10201 ttcttctcaa tcaataaaaa accgtgtccc ttcatccacc aacgaagaaa cacggccgaa
    10261 agttattaag aaaattctga atctacaaga aagtggacaa aaacatgtct gtcctgctat
    10321 caataagtaa gacgtatacc ggcctgcaac gtaaagttac acgggttctc cttgcgtata
    10381 gtctgtatcg acgaaccgtc atcaaagaaa taagatactc ccggttccac atacaggccc
    10441 accctattgc ttatgttata ctgggcaccg acagcaccca tgacagaaag ctgtaccggt
    10501 ttcacagtct cactctcagt accaatcttg ccatacacac atttttcaat ggcacccccc
    10561 gccgaaacgt acatcgtaaa gttctttgca tccacaaagt tccagttggc ccgtaccgga
    10621 atgccaatat aatgcagctt ctggcttatc ttttccgagc tgccctcata ccttacgtca
    10681 gaagcaagat aggtatacgt cagcccgctt tccacagaga aacccttcgc caagtttttc
    10741 cgcaccgaaa caccgaaact gagcggttgt ttatggtcta tatccgcaat tttcttttcg
    10801 cgtctttgca gatagggcat accatcctta aaaaccagtt cctgcccgtc gggaatagta
    10861 acaatgccat tggccgtaga ggataaatct acgttaccgc cataaatagg acttccaggc
    10921 atgtagtccg acatcacatt cgcttcccct tcattcgcca atgaaaaacc tcccgtattt
    10981 cctacggaca agccaaccgc ccatccttta gcatccctac cagaactgtt tttttccgga
    11041 agatgcagtt tgtcccggcc tgacggacga tagcggtctt cccttgtctc cggttcctcg
    11101 gtctgcattg tagtttcatg gtccgtatct tccactaccg gttcttccgc ctgctgtcca
    11161 ataccgacaa cctcatctgc agtttcaacc ggcagcattt cctcctgctg ttcttcgcca
    11221 accgatattc tgatatgttg tgcaaccaaa gggtgacttg cctccttatt gggcgccgat
    11281 gcatttccat gtgcccgata agcaggctct atggaattag tccgtatggc aggtactgtc
    11341 tgttccggca agacgtccgg agccacagcc aaagcgggca ctgacgtatg ccgcatttca
    11401 ttccctaccg gactctgcaa cagccacaga ctgacggacg aaaccgccac cagcaacaca
    11461 gctgccgcgg ccaccgccca gcgacggaaa ggtatcatcc tatgcggtcc ggttatcgga
    11521 gctccggaaa cggacaattc cttctccaac cgctcccatc cggcaaccgg cagcggttcg
    11581 gaatagtctt ccagcttgtc ctttatcttt ttcaaccaca attcatcttc catacgttcc
    11641 ttcatttaat catttctttt catccactca cgtacttttg ccgctaaagt cgctttagca
    11701 cgcgtcaact gcgaggcaga ggatttttca ttaattccca atagtcgagc aatctcctta
    11761 tgggatttct cttcaaaaat atataagttg aatacggtac gatagccggc aggcaattca
    11821 ctgataaact gcattagtac cttttgagga atgacatcta ttgacgaacc ttccggttcc
    11881 tcataagctt caggtgcatt ctccaaggcc gatgactgat tcatcacatc atttttccgc
    11941 aaatactgca acaccgtatt caccattacg cgttccatcc atgcccgcag agaaccctct
    12001 ccccgccaag tgaacttatc gaaagaatca aaaagtttca gaaaaccgtc atgcatcagg
    12061 tcttgggcag tctcccggtc acctgcataa cgaaggcata cgctgagcat gcgtcccgca
    12121 tagcgctcat acagttcttt gcgggcaaga ttgtctcctt gcctacagcg ttctgccaat
    12181 tcctgttctt ccattctctc ttttaacacg tgtttaccct ataaatgcaa tcggcgcaaa
    12241 aatactgcat caggcagaga agaaaatcat actttcattt ctttaacagt atactacgca
    12301 gtatttagct tttcaccgca ttttctgaat acaaaaataa gttttaaaca gaaaagagct
    12361 aaaacctacc acttatgaag aaactgagaa tgacattggc aacatccatg cttttattcc
    12421 tgactgccat tgtattgcaa tcatgcctgg acgattggga tgacaaatat gacactttgt
    12481 tcgccgtagg tacggtaaag gtcatcgaag gaaaagacta ctatttctca ctggacgaag
    12541 gcagtaaact atatcccagt gacacaacct atgttcacga ctatgccgta acagacggcc
    12601 agagggcttt catctacttc cgcgaactgg aagagaaact tccaggctac gaatacaatg
    12661 cccaaataaa gcacatcgaa aatattctga ccaaagacat ctactccatg cctgccgaaa
    12721 aggcggacag tatcggagac gacaacatca acgccacgga tttatggatt acgggtgagt
    12781 atctgaacat caagtatcaa ttctaccaca gtaacaacga agataagaag cacatgctga
    12841 acctggtcat caacgaagca tccaccggcg agaacgacaa accggattac gtcaatctcg
    12901 aattccgcca caatgcctac aatgacagcc agctcacact gggcaccgga ctggcctcct
    12961 tcaagctgga caatatagcg gaacagctga aagagaaaaa aggactgaac atccgcgtca
    13021 aaagtctata tgacggtgaa cggttcatga ccatagacat taaaaaagaa aacaactaaa
    13081 tctcctgaaa acacattttt caacatctca atgagaagcg gagtaacatt tcaatatgtt
    13141 gctccgcttt gtttttccat aacttatcag aattcattgt tcaagcaagt cagcctcaac
    13201 gaagcgttga acgcttcggc agacaatcgc gtcctgacct gtacctgcac gctgctcttc
    13261 ggctggacat caaaataatt gtcgctatat acactttcat tgtcagcaac ggacaagcat
    13321 acggcacggg caaacttgtc tgttgatacc gtcacttcat atccgccttc aatggaacgg
    13381 acttcggtct gcaaatccac tttcggataa ttcatattct tctgcttgtc cagacagtag
    13441 ttgttatggt acaccctgcc cgatttgtcc gtatagtcta cgcggacata taccgttcct
    13501 ctatctgccc cctccagcag cttggcaagc ggtgcggaaa aacagacacg gctgtcatta
    13561 ccggaaatgc cgacagattt gtcccagtga taaaccacag tgccgtcgaa ccggcagacc
    13621 tggagctgca gccggccgga agtattctcc aagcggtcgg acactgcata tactttcaaa
    13681 tcatccccct ccactaccgg agaaatcagg atgtcatcat agaccttgcg agtataatag
    13741 tgctgcgcct tccagcgtcc gtaatagtca cggctcgccc aggaagctac gggccaacag
    13801 tcgttgtgct gccagaaaag cgtccccata ttatacggca tctggcggcg gtgcgactcg
    13861 atggccgtct tgatggcatc tccctgcagc acatggttca tataaaggaa tgcccggaaa
    13921 tcacgcggct ttttatattc attcaatagg taagtctcaa tcagcccgtt ggcatggtcg
    13981 ccaccacgct gatgggacat catcacctcg gaacgtatat cccagtcttc ggggtaagga
    14041 gcatagcgct tgacggagtc gaactctgga aaagactgaa agccgtactc gctgaaaaag
    14101 cgggatttct cgctgtcata atcggaaatg ggtgctttac catgccagac actccaatag
    14161 tgacggtccc cgtcagtagt accggacatc tctccctcga atgcgaacgg agaagaaggc
    14221 caatagaagg ttccgggtgc atactccctg accaccccgg gtaaggtgac atgatactgc
    14281 tgccggtact gtgcccaaat cttgtcggca tattccttgt tctgccgttc tatctcgcac
    14341 ttccagcccc agcccagcca ggcatcctgg cattcattgt ttccacacca caaagcaatg
    14401 caggcatgat tgcgcaaacg tttcacattg tccaccgcct cctgatggat attatcgagc
    14461 agggcgcctt ctgccggata catgctgcag gcaaacataa agtcctgcca aatcataatt
    14521 ccatgctcat cacacaaatc atagaagaca tcgttctcat agatacctcc gccccagaca
    14581 cgcaacatat tcatgtttac accggcggca tcgagaatcg tccttttata attctcggga
    14641 gtgacgcgcg gcaggaagtt atccgaaggg atgtaattgg ctcctttggc aaaaaccgga
    14701 cgcccgttca gctctatata gaaagtatgc ccgtccttat ccggctgatg caccaccttc
    14761 aaagagcgta tgcccaccct ttcggtttta gagtccaaca attccccgcc tgcaatgata
    14821 tccgtacgga aacggtaaag gaaaggctcc cccagtccat tactccacca cagcttcggc
    14881 ttgtgaagga cgaaatcaac ggtcacccga ttggtgcctc gcttcaaatc cgcttgccac
    14941 tcgccaagca ctcttccggt agcctcgtct gttatcgtga ccagcactcc gtccatatcc
    15001 ttatcggcat ccagctccac atgtccggca atcacggccc tgcctgcacc gacttccttc
    15061 tgctcgataa acacatcgtt gattctcaaa tcgctccaag ccctgatata caccggacgc
    15121 cagatgccgg aggtaaccag acgtgggccc cagtcccagc cataatgata acccgcctta
    15181 cgggcaaaaa tgcttatctt cttgttgaac aagcctccgt tttcagactg gtcattggat
    15241 gccggatact ggtaaggaag tgcatcccat ttggggacgt ctatctttac cggcgaatgg
    15301 aagtacacct tcaatatatt attctcctcc ctgatgtact gcctaacggg gatagaccag
    15361 cggcgaaaca tattgtc
//
