LOCUS       c00039_gnlPro..        16453 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOMNIANF_106.
ACCESSION   c00039_gnlPro..
VERSION     c00039_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:47:57
            Original ID  :: gnl|Prokka|NOMNIANF_106
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16453
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16453
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9805:13363](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(9806..13363)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16453
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16453
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             147..1373
                     /locus_tag="ctg39_1"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFTTGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
     CDS             1706..4459
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_2"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             4487..4819
                     /locus_tag="ctg39_3"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(4782..6068)
                     /locus_tag="ctg39_4"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             6541..7767
                     /locus_tag="ctg39_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             7764..8594
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg39_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             8622..9482
                     /locus_tag="ctg39_7"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVIPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(9493..9681)
                     /locus_tag="ctg39_8"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(9806..13363)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_9"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             complement(13397..14602)
                     /locus_tag="ctg39_10"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             14782..15936
                     /locus_tag="ctg39_11"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
ORIGIN
        1 caactaaact ctcctccttc ctgaaggagg ggaatttagt tgcttttgac acatcttctt
       61 ttctgtttct tatttcagta aatgtccccc ttccctgtgt tttgatttac tacttaatct
      121 gttaattatt agaatgataa taacagatgt tcttttttct aattgtcccc ctctttcttg
      181 ccttgtttta taagccgatt gcctatcttt gcggcaggtt tttaaataat aaatcaaaaa
      241 gagaaaacta ctttatgaaa cacatttcga acttcctcag atcaaaaagc tggaacgtat
      301 ttttgttttt atatcttgct cttcctttgt ttgcgcaaaa ggaatataag atcgatcagg
      361 tatctgttgt taatgtaggc gatggcagac tgttgtttca ggaactgaaa acggaaaaag
      421 cattgaatgg cgaacatcgc atcatagatg gttatcattc cgcctatgtg ctggcatctt
      481 ttaaagatgg tttttatgat ggcggataca aagaatatgt ggacaatata ttaataacgg
      541 aaggaagtta taaagaaggg cggaaggatg gcctcttcaa gattaactcc aagtttgacg
      601 gtaagctgaa agaagaaaag tcctataagg aaggtaagct ggacggtacg agcaaaagtt
      661 actttactac cggaaaagtg gaaagtgaaa gaaacttccg gatggggaaa gagcacggga
      721 agcaactgtc gtacgaatct gacggtactt tgcggaaaga gcataattac aaggacggga
      781 agcaggtagg caaacagtat acttttctga aaggtacata tgatttgtat gagaccgttt
      841 atttcaatga agaaggtttt caggacggtg aatattcgtc cgtgtttacg tttggctcgc
      901 cacgtatact gggtagttat aagaatggaa agaagaatgg tcgttggact acttttgctg
      961 aaagcggaga tacgctgatg attgaaacct atctggatgg aaaagaagat ggactccatg
     1021 tctcatttgc caacggaagt ggggtaaggc agaaagaata ttatatgaag aacgatcgta
     1081 aagacggttt ataccgtgaa tataatttgg aaaatggtga attgagatat gaagctacct
     1141 atcaggccgg cagattgcat ggcaaggaac gacggctgat agtgagcaac cgctttgatt
     1201 attgggaaac ttctacctat gtgaacggaa ggcagaacgg accgttcgaa gctcgttatg
     1261 taaagaatga ccagcttcgt gaatgtgggg aatataagaa tggtcaccgt gtaggacgat
     1321 ggaaacgcta cactattgat ggtaaactgg aaaaggaatg ggatgaaaac taaccggtag
     1381 atgaaaggtc agagcataaa aaaaggagca acgccttgct ccaacctttg ttaaccttaa
     1441 atctaatact atgaaaaaca cagtgcaaag atacggactt ctgtgaaatc tgcaaattat
     1501 ccaagtaaaa cgctatgttt tataacattg attaagtgtt tgttttacgc tttatacttt
     1561 tgttaatact ttccgatggt ctgaaagagg actgctttcc ttctttttag aataataaat
     1621 agctgaagtt agagaacttt acagtattat ttcttatttt tgttcttaat tggattacag
     1681 aaagaactat gaaatgatga gatggatgaa gacgatgaga tatctgaagt ggatgctggt
     1741 gctgtttggt ttaatcggga tgacggcttg ccggcaggat acaccccgtt ttcgtattgg
     1801 ggtggctcaa tgcagcgatg attcatggcg acataagatg aatgatgaga ttcttcggga
     1861 agcgatgttt tataatggtg tttcggtgga aatccgttcg gcaggggatg ataacagtaa
     1921 gcaggcggaa gatgtccatt attttatgga cgaaggagtc gatctgctga ttatttccgc
     1981 taacgaagct gctcctatga ctccgattgt agaagaagct tatcagaaag gcatccccgt
     2041 tattcttgta gaccggaaga ttctttcgga taaatatact gcctatatcg gagccgataa
     2101 ttatgaaatc ggtcgttcgg taggaaacta tattgcctcc agtctgaaag ggaagggaaa
     2161 tatagtagaa ctgacaggat tgagcggttc gactcctgca atggaacggc atcagggatt
     2221 tatggctgcc atcagtaaat tcccggatat aaagctgatt gataaagcgg atgctgcgtg
     2281 ggaacgtggt ccggcagaga tagaaatgga tagtatgctt cggaggcatc ctaagattga
     2341 tgctgtgtat gcccataatg accgtatcgc tccgggtgcc tatcaggcag caaagatggc
     2401 agggcgggag aaggaaatga tttttgtcgg catagatgcc ttgccgggta agggaaacgg
     2461 actggaactg gtactggaca gtgtgctgga tgccaccttt atctatccga ccaatggcga
     2521 taaggtactg caactggcta tggacattct ggagaagaaa ccctatccca aagaaacggt
     2581 gatgaatacc gctgttgtgg accgtaccaa cgcacacgtc atgcagttgc agaccacaca
     2641 catttccgaa ctcgacaaaa agattgaaac gctcaacgga cgtatcggtg gctatctctc
     2701 tcaggtagct acacaacagg tcgttttata cggcagtctg attatccttt tattggtagc
     2761 cggcttatta ttggtcgttt ataaatcact ccgctctaag aatcgcttga ataaagagct
     2821 ttttaagcag aagcagcaat tggaagagca gcgtgacaaa ctggaagaac agcgtgacca
     2881 attgatacag ctctctcatc aactggaaga agctacccat gccaagctgg tctttttcac
     2941 caatatttct cacgacttcc gtactccgtt gacattggtt gccgacccgg tagaacattt
     3001 gttggcggac aagacactga gcggagatca gcaccggatg ctcatgctga ttcagcggaa
     3061 tgtgaacatt cttctgcgtc tggtcaatca gattctggat ttccgtaaat atgaaaacgg
     3121 caagatggaa tatactccgg ttacggtgga tgtcctttct tctttcgaag gatggaatga
     3181 gtcttttcag gcggcagccc gtaagaagca tatccatttt tcttttgata gtatgccgga
     3241 tacggattat catacactgg cagacatgga gaagctggaa cgtatttatt tcaatcttct
     3301 gtccaatgcc tttaagttta caccggaaaa cgggaaaata gccgtccgtc tgtcttccct
     3361 tagtaaagag gacaagcgat ggatacgttt cacggtggca aataccggtt ctatgatttc
     3421 tgccgaacat attcgcaatg tattcgaccg tttctataag atcgatatgc accataccgg
     3481 ttcgggaatc ggactggcat tggtaaaagc cttcgtagaa atgcacggtg gtatgatctc
     3541 cgtagagagc gatgagaaac agggcacggt ctttaccgtt gaactgcctg tacagtcttg
     3601 tgaggctgtt gctgccgaac cggataccac ccttgtttct gcggattccc gtacaacaga
     3661 tgttctattg gcggaagagg aagaactgga aaaaggatat gactcttcca aaccgtccgt
     3721 actgattatt gatgataatg aggatatccg ttcgtatgtc catacgttgt tgcatacaga
     3781 ctatacggtg attgaagcgg cagacggctc cgaaggaatc cgtaaggcta tgaagtatgt
     3841 tccggacctg atcatttctg atgtgatgat gccgggcatt gatggcattg aatgttgccg
     3901 ccggctgaaa agtgagttac agacctgtca tattccggtt attctgctga cagcgtgttc
     3961 actggacgaa cagcgtattc agggatatga cggtggtgcg gattcttata tttcaaagcc
     4021 gttcagttca cagctgttgc tggcacgtgt ccgcaatctg atcgattctc accgtcgtct
     4081 gaaacagttc tttggtgacg ggcagacatt ggcaaaagaa gatgtctgcg atatggacaa
     4141 ggattttgta gaaagattca agtcattgat tgaagagaaa atgggagact ccggtttgaa
     4201 tgtggaggac ttgggcaaag acatgggact aagccgtgtg cagctttatc gcaagattaa
     4261 atcattgact aactactctc cgaatgaatt gctccgtatc gcccgtttga agaaggcagc
     4321 ttctttgctt gcttcttcgg acatgaccgt agcggagatt ggttatgaag tcggtttcag
     4381 ttcaccttct tatttcgcca agtgctataa agagcagttt ggagagagcc cgacagattt
     4441 cctgaaaagg aaaggatgat ttcattgata tcgtaaagag ggatatatga aagattataa
     4501 agtagataaa gagagctttt ccgaatcctt tcggaaggaa gtgtacgaag tcgtatccca
     4561 gatacctgtg ggaaaagtat ctacttatgg aggtattgct ttgctgttgg gggcacccca
     4621 atgctcgcgg atggtgggac gtgcattgaa agaagtgccg gatgaattat ccattccctg
     4681 ccatagagtt gtaaattcca ccggaaggct ggtgcccggt tgggtggaac aaaaacaact
     4741 cttgctggca gaagaagttt ctttcaaagc taacggatgc gttaatctga aagaacattt
     4801 gtggcacgtg gatgaatgaa ggatgcaagg aaggtaagcc atatcatccg tatccataca
     4861 ataaagaaaa cccatacatg aagccataag gtcctggtaa tgaaatctct gatgggtata
     4921 gggacgaata tgtcgatagg aacgatacat aacagcacaa aacagcacca aaatagaatc
     4981 ttgtctgttg cggtacgtgt tggtctgctc caataccaga gcatgaaacc tgccaatgcg
     5041 ataatatagg tatgcttctc ggcggagtca ctcagtaata ctacccagcc catgagaatg
     5101 cccaaagcct gggcacggaa ggcaaaagac gaccatttgc ggaaattccc caaaaagagc
     5161 agagtcagca agccgagcat tcctatctga agtgcacgga agtgtggcaa tgtccatgct
     5221 gcaatggggc gggcatagaa aaatgaatca taagctccgg cggactgatg aacagcaaga
     5281 ctatggcacc attcttcata ataggggagc aaatctgcag gagctatttt gattaacggt
     5341 aatgcaagca atacaatgcc cattgtaacg gcatagccaa agttacgcca tacgtgagga
     5401 tagcacagca acaatgccag ttcgaaaatt ccatatactt tggtacatcc cgaaatcatg
     5461 attaacagaa cagccagaaa tccacggtct ttttccaata acgtataggc gaataagaat
     5521 aaataggcta ccgttatgtt atactgaaat gaaagtaaac tttgtcctaa aatcagtaac
     5581 agaaaaagga acatacggca tttctgctgc tgggtgaatt gttggggcag cgtgaagatc
     5641 gccataaaga acagcgaata attgaataga ttccacgcga aaggtcccag ccatgcaggc
     5701 agatacgcaa acggagcgaa caataccgtg aaaactggag aataaaggaa gtagcgtccg
     5761 tgagcttcta caaattcagt tgtgtatggg ctgatgcctt gccagaagaa ttgagtagcg
     5821 tccgagaaga ccataaagtt ttgatgccgt cctcgtataa attcgagcag agtcactata
     5881 aaagcgagca ggaaacctat catgtagaga ttccgccggc tatagaaaaa cggcattttg
     5941 gggttctttt tactaaggaa ctgtacttgg cttttgtcgt ctagtgtggc agtacctgtt
     6001 tgtttttctt ttgttgtgta atgacaatta tccttcccca ggaaaattgt aatagccctg
     6061 ttgaacatat aaatctagtt tagttattga cgccaaatat acggtgttta agtgaaatat
     6121 tcaaacttat tttatattta tctgccggtt tgttctattt tgctgagtga taggggaata
     6181 ttacccggaa actttccata tcattacaaa taaagccctc tgtatgcccc ggattttgaa
     6241 tataatttgt atgtttaatc cgttttttgt atctttgtgc cagcaagata ctggaacagg
     6301 ctgtttttat acataaaaat gctatttttt gctattcgtt gaaaggatta tcttatcaaa
     6361 ttctattcct tttttaatta ctcagtctgt caataatcat tttattaatt atttcgggat
     6421 tcattgttat ttgtccctta tttaaatcag aactttatac gatataaaga aagattcctg
     6481 ttatcgtttg ttcttgtctt gctgtgtata ttattttaat aacctaaacc attttattgt
     6541 atgagtaaaa tagaaattaa agatctctat ctggtttttg gcaatgagaa gcagaaggct
     6601 ttgaagatgt tgaaagaagg taaaacaaaa agtgaaatat tgaaagcgac cggatgtaca
     6661 gttgcggtga aagatgcgaa tctttccatt aatgaaggcg aaatattcgt cattatgggg
     6721 ctgtccggta gtggaaagtc cactttactc cgctgcatca accgtttgat acgccctact
     6781 tccggagaag tgattatcaa tggaacagac atagccaaag tgtcggataa ggaactgttg
     6841 cagattcgcc ggaaagaact ggctatggtc tttcagaact tcggtctgct tcctcaccgt
     6901 tctgtcttgc ataatatagc tttcgggctc gaactacagg gagtaaaaaa gggagaacgg
     6961 gagcagaaag cgatggaaag tatgcaactg gtggggctga aaggctacga gaatcagatg
     7021 gtaagtgaac tgtcgggtgg gatgcagcag cgtgtcgggc tggcgcgggc tttggccaat
     7081 aatcccgaag tcctgttgat ggatgaggcc ttctcggcac tcgatccttt gatccgtgtg
     7141 cagatgcagg atgaactgct gactttgcag tcgaagatga aaaaaacgat tgtctttatt
     7201 actcacgacc tgagtgaagc gattaaattg ggtgaccgga ttgctatcat gaaggatgga
     7261 gaaattgtac aaatcggtac atcggaagaa atcctgaccg aacctgccaa cgcttatgta
     7321 gaacgatttg tggagaatgt agatcgaagc aagattataa cagcttcctc tgttatggta
     7381 gataaaccca tagtggcacg tttgaagaaa gaaggcccgg aggtgctgat ccgtaagatg
     7441 cgcgaacgga atctgaccgt tcttccggta gtcgattcca ataatctgtt agtaggagag
     7501 gtgcggttga atgacttgct gaaactacga aaagagcaaa tccgctccat cgagtccgta
     7561 gtaaggcatg aagttcattc agtgctgggt gatacggtgc tggaagatat tcttccgttg
     7621 atgacaaaaa cgaactcgcc aatctgggtc gtaaatgaga atcgggagtt tgaaggcgta
     7681 gtgccacttt cctcattgat catcgaagta acgggaaaag ataaagaaga aattaatgaa
     7741 atcattcaaa acgcaataga attatgataa atatcggaca atatatagag actgccatta
     7801 attggctcac agaacatttt gcttcctttt ttgatgctct cagcatgggg atcggaggat
     7861 tcatagacgg ttttcagcac gtactgtttg gaataccttt ttatatcaca attgcagtgc
     7921 tggctgcgct cgcctggttt aagtcgggta aggggacagc cgtatttacc ctcttgggtt
     7981 tattgcttat ttacggcatg ggcttttggg aagaaacgat gcagacattg gcattggtac
     8041 tttcttccac ttgtctggca ttgcttttag gcgttccgtt gggaatctgg actgccaaca
     8101 gtgatcgttg taacaagata atgcgccctg tcctcgactt tatgcagaca atgcctgcct
     8161 ttgtctatct gattcctgcc gttctattct tcggattggg aactgtgccg ggagcttttg
     8221 ccaccatcat ctttgcaatg cctcctgtgg ttcgtctgac tggtctgggc attcgtcagg
     8281 ttcctaaaaa tgtagtagaa gcctcccgtt cttttggagc tactccctgg cagcttcttt
     8341 ataaggtgca attgcctttg gcattgccta ctattctgac gggaatcaat cagacgatca
     8401 tgatgtcact ttcgatggta gtgattgccg ccatgatttc tgcgggaggg ttgggagaaa
     8461 tcgtgctgaa aggtatcacc caaatgaaaa tcggactcgg atttgaaggc ggtatcgcag
     8521 tcgtgatatt ggcgatcgtg ctggaccgca tcactcaggg tatggcagat aacagaaaaa
     8581 gtaaaaagaa ataagaatca caccaaagaa aggaataatc aatgaataag ataaaaatga
     8641 ttgcggcaat gtttattgcc ggcatactct taaccttcgt ttcctgcgga gacaacggaa
     8701 agagtaagaa gataagtatc gcttatgcca actggtcgga aggtattgca atgacaaacc
     8761 ttgccaaagc gatttttgaa gatcaggggt acgatgtaaa gttgctgaat gccgaccttg
     8821 cacctatatt tacctctatc tcccgtaaga aagcagacgt atttatggat gtctggatgc
     8881 ctgtcactat ggaagattat atgaaacaat acggggataa actcgaagtt atcggggata
     8941 tttatgatgg tgcccgtatc gggctggtga ttccggatta cgttacgatc aactcaatcg
     9001 aagaactgaa cgcggaaaag gaacgtttct ccggtcagat tgtcggtatt gatgccggag
     9061 ccggtattat gaaagctacc gatcaggcca tcaaagacta tggattggat tataaactga
     9121 tgacttcgag cggacctgcc atgactgctt ccctaaagaa agcgattgat aagaaagact
     9181 ggattgtcgt gacgggatgg acgcctcact ggatgttcga ccgtttcaag ctgaaagttc
     9241 ttcaggaccc gaagctgata tatggaaata cggaatccat tcataccata gcatggaaag
     9301 gttttagcga gaaagaccct tttgctgccg aacttttggg caacattcgt ctgacagatg
     9361 cggaaatcag ctctttaatg actgctctgg aagaggcgca gacaacggaa agacaggctg
     9421 cccgtcaatg gatggaagaa catcaggaac tggtaaacag ttggattcct gagaaagatt
     9481 gatatgcaaa cactacttca accatcctgc cattctttct ttaccataga agtagtagaa
     9541 aagtagtccc agccagctgg taagaacgat taatacaatc gctataagtc ttttctctac
     9601 agccgcattt atattccaaa tctctatggc agctctgaaa gtcagtatca aaccgataat
     9661 ccaaataaca aatccgatca tatctttaga gttttaatga atatcttcgt gagaagtaat
     9721 cgttacttct aagatataaa caaaaaaggc aggaatctgt ttccaggatt cctgcctttt
     9781 attatgtata aagtatttct acttattatt cagctgtatc agctccccag ttttctctgg
     9841 caagacgttt gtagctgttg taacgccatt tagcgttttc ttcagcagct ttaaacagtt
     9901 cttcagcttc agcaggatat tgtttcatta cagaagcgta acgaacttca cccttcaaga
     9961 aaccttggaa gtcttcccag ttaggttctt tgctatccag ttggaacgga ttcttgcctt
    10021 cttcttccaa agcagggttg taacgccaca agtgccagta accgcactta acagcctttt
    10081 cttcttcttc ctggctctta cccataccgg ctttcagacc gtggttgata catggagcgt
    10141 aagcgatgat cagtgatggt cccggatatg cttcagcttc acggatagct ttcagagtct
    10201 gagcctggtc agcacccata gcaatctgag caacatatac ataaccgtaa gtagtagcca
    10261 tcagaccgag gtctttctta cgtacacgct tacctgcagc agcaaactta gcgatagcgc
    10321 ctaccggagt agctttagaa gactgaccac ctgtgttaga gtaaacctca gtatccaata
    10381 caaggatgtt aacgtcctta ccggaagcga ttacatggtc aagaccaccg taaccgatat
    10441 cataagaagc accgtcacca ccgatgatcc attggctgcg tttaacaaga tattgttgca
    10501 gatcagcgat ttgcttgcag tggttgcatt tatctttagc agcttctacc atcggaatga
    10561 tcttttcggc cagttcctta gtcttttctg catccagcat attgttgatc cattcagcaa
    10621 atacttcttt gtattcagcc gggcagcaat cagaagcgat agcttcgttc attactttca
    10681 ccagacgggc acgcatcttt tcgttagcca gttccatacc cagaccaaat tcacagaagt
    10741 cttcgaacaa ggagttagcc catgcaggac cgtgaccctt ttcgttcata gtgtacggag
    10801 tagaaggaac tgaaccggag tagatagaag aacatcctgt agcgttagca accatttcac
    10861 ggtcaccgaa caactgagaa atcagtttca cgtacggagt ttcaccacaa ccggagcaag
    10921 cgcctgagaa ctcaaacaac ggagttgcga actgagagtt cttcacgtta gccttgatgt
    10981 ctaccaggtg ttgtttgctc ttcacgtttt cagcgcagta agtccagtta tcagcttcgg
    11041 ccaactggct ttcaaggtgt ttcatggtca atgccttgcc acccttcttc ggattacccg
    11101 gacagatgtc ggcacagtta ccgcaaccca gacagtcgag aacgtctacc tgaatacgga
    11161 atgtcatacc atcgaatgct ttacctacag ctttcagttg ctcgaactta gcacccttct
    11221 gctcttcagc atcgagtacg aacggacgga tagaagcgtg aggacaaacg taagcacact
    11281 tgttacactg aatacagttt tcagcattcc attcgggaac gaatgcagct acaccacgtt
    11341 tttcgtattt ggaagtacct tgataccaag taccgtcttc gatacccttg aatgcagata
    11401 ccggcagcaa gtcaccgtcc tgtgcattga tcggacgaac tacttcgttg atgaaagcag
    11461 gatcattgtt ttctgctttt gcatcatccg gcaggttagc ccaagcagga tcgacagtca
    11521 gagtcttgta ttcaccaccg cggtctacag cagcgtagtt cttgttaaca acgtcttcac
    11581 ccttcttgcc gtaagactta acgatgaatt tcttcatctg ttcaacagct tgatctacag
    11641 ggattacgcc tgtgatacgg aagaatgcag actgaaggat tgtattggta cggttgccca
    11701 aaccaatttc cattgcaatc tgagttgcgt tgatatagta tacagagatg ttgttctgtg
    11761 caaagtattt cttcaccttg ttaggcaggt tcttagccag ttcttcgcct tcccagatgg
    11821 tattcagcaa gaaagaaccg ttcttacgca aaccacgtgt tacgtcgtac atgtgcaggt
    11881 aagcctgaac gtgacaagca acgaagttcg gagtatttac caagtaagta gaacggatcg
    11941 gagtatcacc gaaacgcaag tgagaacaag tgaaaccacc cgacttcttg gagtcgtaag
    12001 agaagtaagc ctgacagtgt ttgtcggtgt tgtcaccgat aatcttaaca gagttcttgt
    12061 tggcacctac tgtgccgtca gcacccagac cgtagaattt agcttcgaac ataccttcac
    12121 cgcccagagc gatttcttct ttctgaggaa gagaagtgaa cgtaacgtcg tctacgatac
    12181 cgatagtgaa gtggttcttc ggcattggca tagccaagtt ttcgaataca gagatgatct
    12241 gtgccggagt ggtatctttt gaacccagac cgtagcgacc gccaacgata acaggagcat
    12301 tttctgcgcc atagaagcag tctttaacgt caaggtaaag aggttcgccg ttagcacccg
    12361 gttcttttgt acggtcaagc actgcgatgc tctttgcagt cttgggtaca gcagccagga
    12421 agtgtttagc agagaacgga cgatacaagt gtacggcaac catacctact ttttcgccgt
    12481 ttgctaccaa gtggtcgata gcttcgcggg cagcttcagt tacagaaccc attgcgataa
    12541 ttacgcgttc tgcatcttct gcaccgtagt aatcgaacaa accgtatttg cggcctgtga
    12601 tcttggaaat ttcgttcatg tattcttcta cgatagcagg aactgcttca tagtagttat
    12661 tgcatgattc acgatgttgg aagaagtggt cggggttttc agccatacca cgggcaaccg
    12721 gcttcatcgg attcagtgca cgggcacgga attcagccaa agcttcctgg tcgatcagcg
    12781 gagcgaggtc gtcgttttcc aacatttcga tcttctggat ttcgtgagaa gtacggaaac
    12841 catcgaagaa gttcatgaac ggaacgcgtg atttgatagt agccagatga gcaacacctg
    12901 ccaaatccat aacttcctgt acagaacctt ctgccaacat agcgaagccg gtttgacgag
    12961 ctgacattac gtcctgatgg tcaccgaaga tacacaatgc gtgagaagcc agtgtacgag
    13021 cagaaacgtg gaatacacaa ggcaagaatt caccggcaat cttgtacatg ttagggatca
    13081 tcaaaagaag accctgagaa gcagtgtaag tagtagtcaa tgcaccagcc tgaagagaac
    13141 cgtgaactgc accggcagca ccaccttcag attgcatttc ctgtaccaat actgtttcgc
    13201 cgaagatgtt cttacgtcct gcggcagccc attcgtctac gtactcagcc atagtcgaag
    13261 aaggagtgat ggggtagata gctgctactt cagagaacat atacgagata tgtgctgcag
    13321 cttggttacc atcacatgtg atgaatttct tctgtttagt cataactaaa ttaaatattt
    13381 aagtaaataa atctttttag tataagaatc cgaacatcca aagaggtatt tggttgccgc
    13441 ggcctatctc ggccttttgc aacgcatacg tcacgtccgg gttattcttt atttttgtac
    13501 cttccgcaca aattttgaac ggcatcactt cgtctaccat gaaagagacg tttttatctc
    13561 ctttatgtac cttatggtct ttccataaag tgttaacgaa gaacgtgtcg agtacatcct
    13621 gttcttccac tttcaccgga taaatggagt acatcaggtt agagttgtgc atcataatct
    13681 ttgacggttt ctttgggaat tcttctcctt tcgggtaaac cagattaatc agacgcgcgt
    13741 ctgccagata cttgatatag ttcattaccg tagcgcggga tgtctgtacg tcacttgcca
    13801 gttggctcac gttcggagct ttcggtccgt ccacagccaa caaatatagt aattttttta
    13861 tctttgaaag atatttcagc tcaatttgtt tgatcagcaa gatatccact tctaccatca
    13921 tgttcattgt tttcagcaga ttctccgaga aattacgttt ttcaaggaag aaagggtaga
    13981 aaccatgatg caggtaatcc tgaaaataat ccagcggtcg tactttggaa agtactcctt
    14041 tggctatctg ttcatgtgta ctgaggattt cttcgaggct gtatgcccgg aatttcattc
    14101 ctgtctgcag gttcagaaat tcacggaaag agaatccgcg caggttataa cttttcgcaa
    14161 tgtcacgcaa ttcgaggttt tcctctttga gtcgcatgac ggaagaaccg gtgaagacaa
    14221 tcttcaggct ggggaaacgg tcatagcaca ttcgtagctc tttgctccat tcgggatgtt
    14281 tgaacacctg gtcgatcagc agtacttttc cgccacgttt ctgaaactcg ttggcgaagt
    14341 caacaaggct gtgaccggag aaataaaagt tgttcatatt gatgaacaga caggaacggt
    14401 cggtgccgaa tttctctttg gcgtactgca ggaggaaagt ggtttttcct acgccacgtg
    14461 tccctttgat accaatcaga cggtcactcc agtcgatctc gtccataaga tcgcggcgaa
    14521 cgggggcatt ggtgtgctca acgaggtagg cgtgtgtgcg atagaatgat tccatttcgt
    14581 ttctttgttt ttcggctggc aaatatagtg ctttttttag gatttgcaaa gtagagatag
    14641 caaaaatgtg ctttaattta taagtttctc tttattgtgt aagttcctga ttatttcctg
    14701 tatatatttg cagaataatg tgttgaatcc atctttgaca tgacgaaaag acctgtttat
    14761 atattcaatc cggagcatga tatggcgttg gcaagcggtg agacgaacta tatggcgccg
    14821 gcttccgccc gacagatggc gagtgacctg gcgttgcttc ctatgtggta tgccgaagcg
    14881 ggaagtgcgg tgcttgcacc gtctgcttat aatgcggact tcctgaaaac aaagagtgaa
    14941 cttttgggca tggatgtggc cttgttgacg gaaccggaag tggctgacgg taaagactgg
    15001 aagttctctc cgtggggttg ggaccctgct ttgcggaagc gtttgatgac attgggggca
    15061 ggtcagacgg agctgccttc tgcggattat atgaatattc tgagagagca ttcgcatcgt
    15121 ctgcaggcgg taaagttgtt gcctgggttg cggttgaatg aatacttctg tggagaatct
    15181 ttttatttga gtactttggc ggagtgcagt gcgttcgtcg aagggcggga agcgtgcttg
    15241 ttaaaagctc cgctttccgg aagcgggaaa ggattgaatt ggtgtaaagg catatttact
    15301 acttttattt ccggttggtg tgcccgtgtc gctgcttctc agggtggggt ggtaggcgaa
    15361 cctatatata ataaggtgga agatttcgct atggagtttt atgctgacgg gagaggaagg
    15421 gttgtttttg ccggatattc ggtcttccac acgggtggga gtgggatgta tgcagggaat
    15481 gacttgctgt ctgacgagaa gattctgcag aaactatcgg cttatgtgcc acaagaagaa
    15541 tttatcaggc tgcggactcg tttggaagaa gaattgtcag ctttgttcgg tggcttttat
    15601 catggatact tgggagtgga tatgatgatt tgtcattttc cggatgaagc gcctgtttac
    15661 cggattcatc cttgtgtcga aattaatctg cgaatgaata tgggggtggt ggcatggctc
    15721 ttgacggatc gttatttggc tgcggatgcg gaaggagttt ttcggattga ttattatcct
    15781 ttagccggtc aggctttgga ggaacatcgg cagatgtcgg cttcgttccc tttgtccgta
    15841 gagaataatc gggtgtgtgc cggatatttg ccgttagtac cggtgacgcc tcaaagccgg
    15901 tatcgtgcgt ttcttttgct tactctcccc cagtgaaaaa gatagtgctt ttgctctcat
    15961 gctctaacag ttcgtctgta tccctttatt catcgatgtt ttagctgtta gagatccagt
    16021 ggtagcagag tgagagcaag gacttgctct cactctgcat cgtcctgata aatactgttt
    16081 ttactgtgtt attctttgat ttacaggatg ttaatatctg atatctcaac tgttaacgtt
    16141 tgatttctca gatattaata attgagaaat caagtattaa ggactgataa tttatgtatt
    16201 attgactgat atatgattta atgttttcag agagagcagt actattgaag tagctgatgc
    16261 gttcaatgtg attggaacat gcggttaagt caatcaaatc aacagtagtt tcagatagtt
    16321 tcgagcgttt ggaactaaag tttcaagcgt atgaaactct agtttctcac cgatgaaact
    16381 acagtttcac accgatgaaa ctctggtttc aagcaatgga aactctttga agatactgct
    16441 aaattggaat tgg
//
