LOCUS       c00089_gnlPro..        14079 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NOMNIANF_156.
ACCESSION   c00089_gnlPro..
VERSION     c00089_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:47:57
            Original ID  :: gnl|Prokka|NOMNIANF_156
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14079
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..105)
                     /locus_tag="ctg89_1"
                     /transl_table=11
                     /translation="MKKIFILLFVSLALFSCEKEEDNKIFEYQLLPSEN"
     protocluster    1..14079
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1108:4079]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1109..4079
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14079
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14079
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             1109..3337
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_2"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-45, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             3351..4079
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_3"
                     /sec_met_domain="Radical_SAM (E-value: 3.3e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(4072..4521)
                     /locus_tag="ctg89_4"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(4508..4675)
                     /locus_tag="ctg89_5"
                     /transl_table=11
                     /translation="MKEIVNRILDVIMYLIPFFGKRKRDKVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(4735..5238)
                     /locus_tag="ctg89_6"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             5432..5662
                     /locus_tag="ctg89_7"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             5749..7863
                     /locus_tag="ctg89_8"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     NYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGTPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIAGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYPCTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMAKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(7933..8235)
                     /locus_tag="ctg89_9"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVENGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(8201..8554)
                     /locus_tag="ctg89_10"
                     /transl_table=11
                     /translation="MEKKRKIRTYGGYFEAFMETLTEKEQDKIQYGLLLLKTQERLSAK
                     FVKFIRDGVFELRTEYNNNIYRVFFIFDDGNIVVLFNGFQKKSQKTPGHEIDKAVKIKE
                     EYYADKQSSNSRL"
     CDS             8571..8987
                     /locus_tag="ctg89_11"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRRKIGKTQPSFFNFPPHFQISPPIEADFRKYLLSL
                     MCKRSKESDMDNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(9103..9414)
                     /locus_tag="ctg89_12"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(9940..10074)
                     /locus_tag="ctg89_13"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLELIDQKKELSSN"
     CDS             complement(10192..11550)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 153.4; E-value: 2.6e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg89_14"
                     /sec_met_domain="MFS_1 (E-value: 7.4e-47, bitscore: 153.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDPERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     WGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPSNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(11566..12486)
                     /locus_tag="ctg89_15"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKKDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQAPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 attctcactt ggcagcaact gatattcaaa aattttatta tcttcttctt tttcacagga
       61 aaataatgct aaggaaacga acagaagaat gaatattttt ttcatattaa tactatttag
      121 tttttgcaaa ttaaaggatt tttcctgcac aataaaatac caattaattg gtattttatc
      181 acaaataacc attcaatttc attattatgc ccaaagcatg aaaataaaag tataacatac
      241 aagagctgta aacaaatcca ctatcaacac aataaaataa atcgtttttg catctttgcg
      301 atatgcattt atgcaaaatc atacaaattt ctttatcagt aaaataccca ttaattagta
      361 tttcattgac aaaatgaaat gtactttaaa agcccaaagt tatattcaat tcataaccta
      421 aatgcctatc caatataaaa ataatgcgtt tagcaccaag atacaaacag aataacacaa
      481 aatcaagctc taaaggaatg tattactatt ataaaagaca gaattattcg ggagattccc
      541 tactctaaaa aagttaaaga aagaaaatga ttcaaataaa tattagtgta acaatatcag
      601 caacaacaca atatcccctt ttcaaattat acaataaata atagttaagc aaccaaagac
      661 agtgcaaagc caaataagta ataaaagaac aaagtattaa ataaagcaaa acacccaatt
      721 ttacttttta gggtgtaaaa ttgggtgttt ttcttgtaaa tcactgattt tcagcgttta
      781 ttgcggagag acagggattc gaaccccggg tacctcgcgg tacaacggtt ttcaagaccg
      841 ccgcaatcga ccactctgcc acctctccaa aacttcctta tcagaagtgc ttttcgttaa
      901 aagcggtgca aagatacgaa gatattttaa acttgcaaga gttttcacta aaaatttaat
      961 ctaatctttt cctaaggata gcaattaata ggtattttat gttgaaaagc ataaaataga
     1021 gcatatttat gctgattata tgaaaaatga ttgtaacttt gtgcgctcta aagaatagga
     1081 taactacaac ctctaatttt atcattttat ggaattaaac aagatcttta aagacggtct
     1141 ttggagcagc gaaatcaacg tcagagattt cgtaagtcat aacatcactc cgtattacgg
     1201 agatgcttca ttcctcgaag gacctacaga acgtaccaaa gccgtatgga accgctgcct
     1261 cgaagcactg gcagaagaaa gagaaaacaa cggtgtccgc tcattagata atgttaccgt
     1321 atcaaccatc acttcccaca aggccggata tatcgacaag gaaaacgaac tgatcgtcgg
     1381 cctgcagaca gacgaacttc tgaaacgtgc catcaagcct ttcggaggta tcaacgtagt
     1441 cagcaaagcc tgtcacgaaa acggcgtgga agtggacgac cgcgtaaaag atattttcac
     1501 tcactaccgc aagacgcaca acgacggagt attcgacgta tatacggaag aaatccgttc
     1561 cttccgttcg ctgggattcc ttaccggact tcccgacaat tatgcacgcg gacgcatcat
     1621 cggtgactac cgccgtatgg ctctttacgg catcgaccgt ctgatcgaag caaagaagga
     1681 agatttgcac aacctcaccg gtccgatgac agaggcccgc atccgcctgc gcgaagaagt
     1741 ggcagaacag atcaaggcac tgaaagacat gaaagtgatg ggcgaatact acggtctcga
     1801 cctgagccgt cctgcttaca cggcacaaga agccgtacag tgggtatata tggcttacct
     1861 tgccgccgtc aaagaacaag acggtgccgc catgtcactg ggtaacgttt cttctttcct
     1921 cgatatctat ctggaatatg aactgagcaa aggaaccatc accgaatcat tcgcgcaaga
     1981 gctgatcgac cagtttgtca tcaagctgcg tatggtccgc cacctgcgta tgcaatcata
     2041 caacgacatc tttgcaggcg acccgacctg ggtaaccgaa tctctgggcg gacgtctcaa
     2101 cgacggacgt accaaagtga caaagacctc cttccgtttc ctgcagacat tgtacaacct
     2161 cggcccttca ccggaaccga acctgaccgt actctggagc ccggaacttc ccgaaggatt
     2221 caaagaattc tgtgcaaagg tttctatcga cacttcttct atccagtacg aaaacgacga
     2281 cctgatgcgt gaagtacgtc agtccgacga ctacggaatc gcctgctgcg tatcatacca
     2341 ggaaataggc aagcagattc agttcttcgg tgcccgttgc aacctggcca aagccctgtt
     2401 gcttgccatc aacggcggac gttgcgagaa taccggtaca gtcatggtga agaacatccc
     2461 cgtactgacc agtgacacgc tgaagttcga agaagtaatg gacaactaca aaaaagtgct
     2521 gaccgaaatc gcccgcgtat ataacgaagc gatgaacatc atccactata tgcacgacaa
     2581 gtattactac gagaaggccc aaatggctct tgtagatacg aacccgcgca tcaacctggc
     2641 ttacggtgta gccggacttt ccatcgccct cgattcactg tctgccatca aatatgcgaa
     2701 agtaactgcc cgccgcaatg atatcggtct gacagaaggc ttcgacatcg aaggagaatt
     2761 cccttgcttc ggtaacgaca acgacaaggt agaccacctt ggcgtagacc tggtatactt
     2821 cttcagcgaa gaattgaaga aattgcctgt ttacaagaat gcccgtccta ccctctcctt
     2881 gctgactatc acttccaatg tgatgtacgg caaaaagacc ggtgctactc ccgacggacg
     2941 tgccaaaggt gttgccttcg ctccgggtgc caacccgatg cacggacgcg acaagaatgg
     3001 tgcgatcgct tctctgagct ctgtagcgaa acttcgttac cgtgactcac aggacggtat
     3061 cagcaacacc ttctctatcg ttccgaaatc actgggtgct acggacgaag accgtatcga
     3121 gaacctcgta acgatgatgg acggttactt caccaaaggt gcccaccacc tgaacgtaaa
     3181 cgtactgaac cgtgatatgc tgtacgatgc catggagcat ccggaaaact atccgcagct
     3241 gaccatccgc gtttccggct atgccgtaaa cttcgtgaag ctgagccgcg aacaccaact
     3301 ggaagttatc agccgtagct tccacgaacg tatgtaatct attactctat atgatgataa
     3361 acgtacattc atacgaaagt atgggaacat tcgacgggcc gggcttacgg ctcgtcgttt
     3421 ttcttcaagg atgcaacttc cgctgcctct attgcgccaa tccggatacg atagcaggaa
     3481 agggaggcac gcctacccca ccggaagaaa tcgtccgcat ggcaatgagc cagcgcccct
     3541 tcttcgggaa acgaggagga atcactttct ccggaggcga accgacgttt caggcgaaag
     3601 cactcgtccc gctggtccgc gaactgaaag aaaaaggcat ccatgtctgt ctggacagca
     3661 acggaggact ttggaacgaa gacgtagaag aattattcag actgaccgat cttgtgttat
     3721 tggatataaa ggaattcaac cctaaccgcc atcagacgct caccggaaga agcaacgagc
     3781 aaaccatccg cacggccgcc tggctggaag aacaggagaa acctttctgg ctacgctacg
     3841 tgctagtgcc cggatacagc gattttgaag aagacatacg cgcactggga gaagcactcg
     3901 gaaaatacaa gatgatccaa cgggtggaaa tactgcctta ccatacactg ggcgtacata
     3961 agtacgaagc gatgggacag gaatacaaga tgaaaggggt aaaagaaaat acccccgaac
     4021 agcttgaaaa agctgcggag gtattcaaag agtatttcac tacggtggta gttaattaat
     4081 ggagaattct ccaatgacct caaagcaagg gcattcttta atccgttccc aaggatctac
     4141 gatcccatta tagttggtgt cgggacttaa gtcccgatga cctactacct tagcttccgg
     4201 ataacgctgc aacaattcgt gtaccaagcg atgtaacgcc tccttctgac ggggtgtacg
     4261 cgtatccgcc gcttttccat tctcatccag accgccctca tagcatacac ctaagctgat
     4321 cgcattatag ccacgtgcat gagctccgac cgtatcttca tcccgcatcg gctcaatctc
     4381 gcccgacttg cgtatataat aatgataccc ccagcacgaa aagccacgat aacggtgagc
     4441 cgtatccaca tcctttgccg taaagtcgca atcgacacgg gtggcggaac aatggatcac
     4501 aatcagacta atctttctca tgttcctttt ccctttccgt cgttttcact ttgcacacct
     4561 ccttacaagt agtatgatag cgcacttctc tcaccacctt gtcccgcttt ctctttccga
     4621 agaaaggaat cagatacatg atcacatcta aaatccggtt tactatttct ttcatcttat
     4681 caaaatatta atggaagtta ttctaattcg ttattacctt gacccgtctg ccaattatac
     4741 cgtagggtcc ggagcctctt catcaccgga gccatcacca ccggaatccg gattcttgtc
     4801 agggtcttct cccccgccat cgcctgcacc cgcctgcgcc accgcacgag tctgcacttg
     4861 ctgataactc agaatcttca tcaactccgc cagcgtctta ccggggcgga aaataagatg
     4921 cgccccctta atcattgaac cggaaaattc cttgaccgat gccgcacctt cactgttgag
     4981 tcctatctgc aaactgccca aatcgcccag tctcgcaatt cttcctgcct tcaacgcacg
     5041 tttcacttcg taaagaatac ccgaaatagc cgcacgtaca tccgtttccg tacaagtaga
     5101 acgactggtg atcgcttcgc acaactcctc aaagtccagc tcacccgacg cctgcgcctg
     5161 tgcataatac tttgccggtt cgctcttttt tgcaggattc ttgcgcggca ccactgaata
     5221 agatactgtc attgccataa taaaataatt ttaaagttta taatacatag gatgcatccc
     5281 cttcttgtta acagcacaaa gataaggata gccggacaag ccatattccc caacgaagtt
     5341 tcttgattcc caacgaataa aaacgaagtc aaacctttga aaaacaagga attttatgta
     5401 actttatagc ataaaacaag aagaaaacat catgaattac aaagaagatt ctttccttat
     5461 ccgcacctat accaaagcgg aactggctca cctttacaat ccccatgtct gccttaaagt
     5521 tgctttacaa atacttcgtc gttggattat ttacaacctc cctctcctgc acgaactcga
     5581 gcaggaaggt taccgcgcac gcaaccgtct cctttcgccg aaacaagtgg caactatcat
     5641 acactttttg ggcgaaccgt agtaacttat tgccatttta tacaaagttc ctttacacat
     5701 ttccgcaaag aagttccttt gcatcgacaa acaataatca aaataaaaat gaaacatttc
     5761 accatatttc aaggtttcta ctacgcaata gcagagatga ccgaagaaga aatagtgtcc
     5821 actatcggca gttttaccta ccgggaaaaa gtcgaagaaa tacgccgcat ctttgcagag
     5881 caaggagaaa aggctgccaa tgagaagaaa aaagaattgc cggcaatcgc cttctccgcc
     5941 agctaccgag gaaggcgtac caaagtgaat ctcgtcaaat atctgggaca catcgtgata
     6001 gacatcgacc acctcagcaa agaagaattg gcacgcatcc tccctatcat caagagatgc
     6061 aattacaccc gcatcgcctt tatcagtccc aaagggatgg gcgtgaaaat catagtacgc
     6121 gcatgccatc cggatgagac attgcccgaa acccttcagg aaatagaaga cttccatcat
     6181 gcagcttaca ccagactcgt ttctttttac accgaactct gtcagataga aatcgacacc
     6241 tccggtcagg atgtggcacg cacttgtctg ttctcttacg atccggagat ttatttcaat
     6301 ccgaacgctg acgcttttct tgtagatcaa cctcaggcat cctacaaggt ttcaaatcgt
     6361 aaaaatctct ccggcagtaa acaacagact cctccggacg gcaccccgac gaatgaggac
     6421 acagcgctca acgcccattc cgccaacgct tctctggtgc tgactttaac ctactatcac
     6481 aacaagtccg aaaaatacat agcgggcaac cggaacaatt atctgcacca tctctcatgt
     6541 accttcaatc gctacggcat tccgcaggag gaagcatccg cctttatcaa aagccagttt
     6601 acagactttc cggcggacga gacagcctct ttgatcaata gcgcctacgc tcataccgac
     6661 gaatttaata cctgtaaact gaatggcacg cagaaacgaa tattacggat agagcaatat
     6721 atcagcgagc actacgaaac acgctacaac gaagtgctgc atatcatgga atatcgtaga
     6781 aggcatcccg acaccgagaa accggagcct ttccgcatct tggatgagat gatggaaaac
     6841 agtatctgga tagaaatcaa cgagctggga tatccctgca ctgtcaaaac aatcgaaaat
     6901 ttgatttact ccgatttcag ccagtcgtat catcccattc gcgagtattt tgaattactg
     6961 cccgaatggg acggaaccga ctatatccgt atcctggcgg atagtgtcca gacgagtcat
     7021 caggagtttt gggcggaatg cctggaacgt tatctggtgg cgatgtgcgc agcggctact
     7081 caggagaata ttgtcaatca cacggtactt ctgctatgca gcgagataca gaacatagga
     7141 aagactacct ttatcaataa tctcctgcct cccgaactgc gtgcttatct ctctaccgga
     7201 ctaatcaatt cgaacaataa agatgattta gccaaaataa cgcaggctat gctgatcaat
     7261 ctcgacgagt ttgaagggat gagcggccgg gaactgaatg cattcaaaga tttggtaacg
     7321 cgcaaagtga tcagtttccg tctgccttat gcacgccgtt cgcaaaactt ccctcatacg
     7381 gcctcttttg caggaacctg caattatcag gaagtgcttc acgacacgac aggcaaccgg
     7441 cgtttccttt gttttcatcc ttattccatc caatttatta ccatcaatta tgcgcagctc
     7501 tatgctcaga tcaaatatct gctgaataag ccggggtacc aatactggtt cacgcaagcg
     7561 gacaatgaac ggcttgaaga gaataacgag gctttcatct ttcattcacc ggaagaagaa
     7621 atggttctta cgcatatccg caagccggaa cgttttgaga aggtttatta tctgactgtc
     7681 agtgagattg cggaactaat acgtgagcgt accggttatc agtattccat cggatcaaaa
     7741 atacagttgg ggaaagtgat ggccaagcac cattttgaat ccaaaaaagg aaataacggg
     7801 cgccgatatg ccgtatttat tatagatatc gagcaggtaa aatcaaacag gctgtatgaa
     7861 tagaagcggg aaagccctgt gaatatagat aaatgcagag tcatcttgac agatactctg
     7921 catttattgt ttttacaaaa tcattgaaaa ttcgatttta cagcctaacg cattcatgat
     7981 acgatagaaa gtagatactt taggctctgt ctgaccattt tctactcttg aaatataaga
     8041 acggtcagag ccgatacgcc gggctaattc agcctgagtg attttagcct tttttcttgc
     8101 gtcctcgata atctgtcctg tataaaaggc gtaggccttt tcttctgcct ctgcacgctc
     8161 gggagtacct tcagcaccaa atttggcatc aaggacagca tcataatcta ctatttgatg
     8221 attgtttatc tgcataatat tcctccttta ttttaactgc tttatcaatt tcatgaccag
     8281 gtgttttttg tgacttcttt tgaaagccat tgaacaacac aacaatatta ccatcatcaa
     8341 atatgaaaaa tacccggtat atattgttat tatattctgt gcgaagttca aaaactccat
     8401 cccgaataaa cttcacaaat ttagcggaga gtctttcttg tgttttcaac aagagtaatc
     8461 cgtattgaat cttatcttgt tccttttcgg ttaaagtctc catgaaagcc tcaaagtaac
     8521 ctccgtatgt acggatctta cgtttctttt ccataacgca aatataagga atgttgttca
     8581 actatacaac acatttcctc gttttatatt atttttcatc atcttcaccc ccaaaagtga
     8641 gaggagtgag agaggaattg aaactttttc tattttattt ctttatttct actttctata
     8701 tttctctaaa aaaaatacga atgttagaaa tcctctctca ctcctctcac tttttacctt
     8761 ttctttctcc aaaaagacgg cggaaaatcg gaaaaacaca accgtctttt ttcaatttcc
     8821 caccgcattt tcaaatcagc ccaccaattg aagcagactt caggaaatat ttgttatctt
     8881 tgatgtgcaa aagatcaaaa gaatcagata tggacaactt gatgcgtaaa cttcctattg
     8941 gaatacaaac ctttgaagat atacgaagga agaatatctt attgtaaaga tcggaatgga
     9001 atttagtgca gaaagccgga acttaaatcg ttggttaatc gaagtgatag gaaagtaaaa
     9061 tatgaaaaac cgaaggatta agatatcctt cggttttttc gactatatac ccatgattgg
     9121 ttttacgatt tcaatcttca atcctaatgc attaataatt cggtagaatg ttcctacact
     9181 tggatttata gctccgcttt caatacgtga gatatacgat ttagttgcat tgattctctt
     9241 tgctaattca gactgagtta cttttgcttc ccgtcgtgca tccaacagta tttgaccagt
     9301 ataaaaagcg tatgcctctt catcgaactt ttcacgttcc ggagtcccag gtgctccgaa
     9361 ctccttatca agttctgcgc tgatatcagt cagcatgttg ttttttgtac tcataatatt
     9421 cctcctttat ttttaatgcc ttatctattt cagatgatgg ggttttctgt tccaagcaat
     9481 gaaagcacat atttcacttt ttgaatttcc ttttctgtca gagtggcaag aaaatccttg
     9541 tagtattgac cgtatgctat tacttttctt ctcattgtgc aaatataata aaagtttcaa
     9601 tatcatacaa cttttaaagt caaatttata ctgctaacgg gcttaaattc cctctcaggt
     9661 actcatttta ttcgaatttc ccttccgaat aatctgaaaa ctccccggca cgttctttct
     9721 tctcatacga gaccaacgtt tcgatactga gcgctttccc gttcttaggg cttatgacat
     9781 ctatcacact tgacaaggac cggaacgtct gttcgcaatt cgcatctcca ctatacgtca
     9841 acctcccccg gtcaatggca cctagaataa cagaaacata ccgtttcgga tctccccgat
     9901 attcgataac agtgggcgtc atttgttctt cttcccgaat cagttggacg acaattcttt
     9961 tttttggtca atcagctcca acagtttttt actatgcaca ctgatttgtg catctacttc
    10021 acgaagttca ttcttcaatg aacaaaacaa ttcatcactc aatgaatttt ccataaaaac
    10081 gatttttatt aattataaaa aagccattcc ggaaagcaca gctattgcct gcttcccgaa
    10141 atggtgacta ataccttcaa aaacaatgac tctattttta ctttaatgta ctcaatttat
    10201 ttcacttctt ttctctcctg cattccaaac caacaaagca aacactactg aaagcaaggc
    10261 tgcaccaatc caaaaccaat tgatatatgt aaaatcgtaa acttctactc cattttgcac
    10321 cgtcttctga ccttcgatca gaatgccact catcacatcc tgcaaaccgg ctcctatata
    10381 actcgctata ccgacaactc ccaaagcggc tcccgaagca ttgctgggag caatatcgac
    10441 agccatcagt cctcctaaaa aacaaatcag cactccaatg cccaaaccga agagcaccat
    10501 cgccaaagca tccacccaaa aatgtacccc cggaaccaat agaaacaaac aaagagcaga
    10561 cacattcatt aatccgaata tcaaagccgg aacattacga ctgccagcaa aaaacttatc
    10621 tgaaataata cctgagaaaa ccgtacctac aattccgcat acagaactga tagatataat
    10681 aaaactagca tccaaagtag aataaccttt ttgcgcttcc agatagaaaa caccccagct
    10741 attgactgca taacggctga tatacataaa agcactggat aatgcaagaa tccaaatagc
    10801 aggattcttc aaaactgctt tctgagcttt attgaattcc tcggtttgct taccggaaac
    10861 ggaatgagca tctgacgtcc cccaccgatc tagcaaaaag ccctgacttt gaggcgtatc
    10921 acgcataaaa gcaagcatca tcagaaaacc aagcaaacca atcactcccg caccgatcat
    10981 cccataacgc catcccatcc aactgaccag caaagcgatg gatataaaag tcagagcttc
    11041 acccaaattg tggctggccg accaaaagcc ataaaaagta cctcgctctt tactactata
    11101 ccaacgagtc agcgacacaa ctcctgatgc tgcccccatc gactgaaacc aaccattcaa
    11161 cccccaaagg agaacaaaag caaagaagga attcgtgaat cccagacata agttgatcag
    11221 agcagaacac aataatccgg tagacataaa acgctttaca ttgctacggt cagcaagaaa
    11281 gccattggtc agcttaccga cggcatatac gaaaaaaagg caggaaccga taatccccag
    11341 ttgggtttcg gtaaaaactc cgtcttctac aatcggttta cggattacat tcatactcaa
    11401 acgacaaaca taataaatgc catatccggt agtggcagac agaaaggtag cccaacgaat
    11461 acgcttgaaa cggacagagc gttccggatc agtctctccc ccggacaccg gaggagagat
    11521 tttataaaaa tccaatagtt taaatcccat aaagaagtct atattttaat gatacgcatc
    11581 ttggccgttt tcactacgct tcttacgcga ttgcaaatat tccagcagat aggcagtacg
    11641 gtctgtctga atgatggccg ctccgagtgt atcgatcaga taaccatatc cttcgtccgg
    11701 attctccaac gatttatcat catcatgtcc gccagccatc gtatcccaca acgtattata
    11761 ccagatttta ctttttcctt tcaacttcgt ttttacttgc ttgggggcct ggcaggtatc
    11821 cgatacaaat agaagttcaa aagctacggg atgcagctcc gtcataaaat catccagttg
    11881 cttcattgct cccggcttat ccaaatgaat gataggcata taaatgatac ggtccagata
    11941 tttacctaag tctttcttta cgtctgccac aggcttggaa cctttcatga taatctgatc
    12001 cactgttccc gtcttttcga ggatgggaaa aatctcgtca aatatcggat atgctttatc
    12061 cagattgacc atcacacgac ctttggcaac ccataaagcc tcttccaaag taggtacacg
    12121 atgcttggtt ttgagtgccg ctccattttt cagatagagt gtccggatag aatccaatgt
    12181 ccattcggct acctttcctt ttccggtagt cgttcggtcc agcgttttgt catgcatcag
    12241 gatcaattga ccgtctttgg ttttctgaac atccagctcc actacgtcag ctcccagacg
    12301 aatggaactt tcaatagcgg caagtgaatt ttcgggtgcg taacgccagt ctgcccgatg
    12361 agctacaacc gtgatttctt tattgtcagg gttcgttatc ttcgcataaa tggctttcac
    12421 cggttcgtct gccgacaggc agaaaggaaa tgcgaataag attcctatca ttatatattt
    12481 cttcatatct atatgtacta ttatctgtat cctttagact ttaaatattt ggcagctact
    12541 tcagcatagt ctgtttgcac aatgttgatg cgtttgttaa tcattcccac caaaccggag
    12601 tagttttccg acaacatatt ggtatcattc gctccgacaa tgttggagaa aagaagccag
    12661 cctttatctt taatctcatt aaccatcgtt ccacccatag catctgacgt agacagctgc
    12721 atcatttgta cattatcagt gtaggatgag gagaagtatg tgatgtcatc ggtagctttc
    12781 gccatcgggt gcaacagcaa actactgttg gctgccttca aatcaaatgc ataattgcga
    12841 ttgttggata catacagcaa agtggaacct tccatatcca attttttaag caatgcgacg
    12901 atcgtattta ccgcaacatt cttgttgaca atatccagat tataataaac ttttcctttt
    12961 cctttcttca tcgcttcctc caaagtcggg attcgttcgc cagttatatt gccggatgca
    13021 tctttcagat aaaattgttg taattgctga taagtaaagt ctcccaccgc accgctaccg
    13081 tttgttgtcc ggtcgatggt gttgtcgtgc atcaatacca acacaccgtc agaggtcggc
    13141 cgtgcatcca gctcgatcat ctcaactcct gctttgaccg agtgttctat cgcaggtaac
    13201 gagttttcgg gaatcccctc tttcatccct ttttgggtat ttccacgatg cgcgcagagc
    13261 cacactttat aagaggtgct ttcaaacaga ctctttaaat ctgctttcaa attccccgtc
    13321 acaggcaact gtcctccttc ttctccaccg ggattctctc cattccctcc cgattgggct
    13381 ccggagtgac gtctgtcctt ccctttcatc ggccaggcag aggttgcggc cccggtaatt
    13441 ccctcatctt ccaaagctac caacacgctc tttgtagggt ccaccgtatt ggtgactccg
    13501 atataaatcg ctccatccgg tccgatggta ggcgaactcc agattttacc gattcccgct
    13561 tcccaatctc cttttaaagg agagtcactt tcactaatca acgcagcaag gtcttttttc
    13621 agaatcaatt gttcatccga ttcttccggt ttaatgatat aataattgcc ggactgggtg
    13681 ccgaaatgta tgtttcctgc ttgatcaatt gccgcacaac cgcttacatc ttccgcaatg
    13741 ccgtaatgcc attggatagc tcctcccgga gacaaagaga tgattcctcc ggttgcttcc
    13801 cccggagcac gtttcactgt aacgataatg cttccgtcga gtcctatcac aacaccgcct
    13861 tgatccagcg tgccgacatt gcccaaagga gtacgccact tctccactcc atcacttcct
    13921 atagcaaatg cgctacttcc cattcctgca aacgtagctg ttccgtaaat agtaccagcc
    13981 tcatctactg ccggagaacc gttcatattt tctgacggct tatcatcgcc ggagctaaat
    14041 acctgccaag cccacattac atttccaccg gcattcaac
//
