LOCUS       c00058_gnlPro..        16467 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OHIDOHOF_86.
ACCESSION   c00058_gnlPro..
VERSION     c00058_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:29:18
            Original ID  :: gnl|Prokka|OHIDOHOF_86
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16467
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16467
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3124:6682](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3125..6682
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16467
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16467
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(552..1706)
                     /locus_tag="ctg58_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDRKFSPWGWDPALRKRLMTLGADQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1886..3091
                     /locus_tag="ctg58_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             3125..6682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_3"
                     /sec_met_domain="PFOR_II (E-value: 5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.1e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.8e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.6e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6807..6995
                     /locus_tag="ctg58_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(7006..7866)
                     /locus_tag="ctg58_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7894..8724)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg58_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.9e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8721..9947)
                     /locus_tag="ctg58_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10420..11706
                     /locus_tag="ctg58_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFIRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFMAIFTLPQQFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVTMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSAGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPIPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11669..12001)
                     /locus_tag="ctg58_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGAPQ
                     CSRMVGRALKEVPDELSIPCHRVVNSTGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(12029..14782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 7.4e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPRFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAEPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
     CDS             complement(15115..16341)
                     /locus_tag="ctg58_11"
                     /transl_table=11
                     /translation="MFFFLIVPLFLALFYKPIAYLCGRFLNNKSKRENYFMKHISNFLR
                     SKSWNVFLFLYLALPLFAQKEYKIDQVSVVNVGDGRLLFQELKTEKALNGEHRIIDGYH
                     SAYVLASFKDGFYDGGYKEYVDNILITEGSYKEGRKDGLFKINSKFDGKLKEEKSYKEG
                     KLDGTSKSYFITGKVESERNFRMGKEHGKQLSYESDGTLRKEHNYKDGKQVGKQYTFLK
                     GTYDLYETVYFNEEGFQDGEYSSVFTFGSPRILGSYKNGKKNGRWTTFAESGDTLMIET
                     YLDGKEDGLHVSFANGSGVRQKEYYMKNDRKDGLYREYNLENGELRYEATYQAGRLHGK
                     ERRLIVSNRFDYWETSTYVNGRQNGPFEARYVKNDQLRECGEYKNGHRVGRWKRYTIDG
                     KLEKEWDEN"
ORIGIN
        1 cagtattacc acaatatgac ttttccgatg ttcaccaatt ccaatttagc agtatcttca
       61 aagagtttcc attgcttgaa accagagttt catcggtgtg aaactgtagt ttcatcggtg
      121 agaaactaga gtttcatacg cttgaaactt tagttccaaa cgctcgaaac tatctgaaac
      181 tactgttgat ttgattgact taaccgcatg ttccaatcac attgaacgca tcagctactt
      241 caatagtact gctctctctg aaaacattaa atcatatatc agtcaataat acataaatta
      301 tcagtcctta atacttgatt tctcaattat taatatctga gaaatcaaac gttaacagtt
      361 gagatatcag atattaacat cctgtaaatc aaagaataac acagtaaaaa cggtatttat
      421 caggacgatg cagagtgaga gcaagtcctt gctctcactc tgctaccact ggatctctaa
      481 cagctaaaac atcgatgaat aaagggatac agacgaactg ttagagcatg agagcaaaag
      541 cactatcttt ttcactgggg gagagtaagc aaaagaaacg cacgataccg gctttgaggc
      601 gtcaccggta ctaacggcaa atatccggca cacacccgat tattctctac ggacaaaggg
      661 aacgaagccg acatctgccg atgttcctcc aaagcctgac cggctaaagg ataataatca
      721 atccgaaaaa ctccttccgc atccgcagcc aaataacgat ccgtcaagag ccatgccacc
      781 acccccatat tcattcgcag attaatttcg acacaaggat gaatccggta aacaggcgct
      841 tcatccggaa aatgacaaat catcatatcc actcccaagt atccatgata aaagccaccg
      901 aacaaagctg acaattcttc ttccaaacga gtccgcagcc tgataaattc ttcttgtggc
      961 acataagccg atagtttctg cagaatcttc tcgtcagaca gcaagtcatt ccctgcatac
     1021 atcccactcc cacccgtgtg gaagaccgaa tatccggcaa aaacaaccct tcctctcccg
     1081 tcagcataaa actccatagc gaaatcttcc accttattat atataggttc gcctaccacc
     1141 ccaccctgag aagcagcgac acgggcacac caaccggaaa taaaagtagt aaatatgcct
     1201 ttacaccaat tcaatccttt cccgcttccg gaaagcggag cttttaacaa gcacgcttcc
     1261 cgcccttcga cgaacgcact gcactccgcc aaagtactca aataaaaaga ttctccacag
     1321 aagtattcat tcaaccgcaa cccaggcaac aactttaccg cctgcagacg atgcgaatgc
     1381 tctctcagaa tattcatata atccgcagaa ggcagctccg tctgatctgc ccccaatgtc
     1441 atcaaacgct tccgcaaagc agggtcccac ccccacggag agaacttccg gtctttaccg
     1501 tcagccactt ccggttccgt caacaaggcc acatccatgc ccaaaagttc actctttgtt
     1561 ttcaggaagt ccgcattata agcagacggt gcaagcaccg cacttcccgc ttcggcatac
     1621 cacataggaa gcaacgccag gtcactcgcc atctgtcggg cggaagccgg cgccatatag
     1681 ttcgtctcac cgcttgccaa cgccatatca tgctccggat tgaatatata aacaggtctt
     1741 ttcgtcatgt caaagatgga ttcaacacat tattctgcaa atatatacag gaaataatca
     1801 ggaacttaca caataaagag aaacttataa attaaagcac atttttgcta tctctacttt
     1861 gcaaatccta aaaaaagcac tatatttgcc agccgaaaaa caaagaaacg aaatggaatc
     1921 attctatcgc acacacgcct acctcgttga gcacaccaat gcccccgttc gccgcgatct
     1981 tatggacgag atcgactgga gtgaccgtct gattggtatc aaagggacac gtggcgtagg
     2041 aaaaaccact ttcctcctgc agtacgccaa agagaaattc ggcaccgacc gttcctgtct
     2101 gttcatcaat atgaacaact tttatttctc cggtcacagc cttgttgact tcgccaacga
     2161 gtttcagaaa cgtggcggaa aagtactgct gatcgaccag gtgttcaaac atcccgaatg
     2221 gagcaaagag ctacgaatgt gctatgaccg tttccccagc ctgaagattg tcttcaccgg
     2281 ttcttccgtc atgcgactca aagaggaaaa cctcgaattg cgtgacattg cgaaaagtta
     2341 taacctgcgc ggattctctt tccgtgaatt tctgaacctg cagacaggaa tgaaattccg
     2401 ggcatacagc ctcgaagaaa tcctcagtac acatgaacag atagccaaag gagtactttc
     2461 caaagtacga ccgctggatt attttcagga ttacctgcat catggtttct accctttctt
     2521 ccttgaaaaa cgtaatttct cggagaatct gctgaaaaca atgaacatga tggtagaagt
     2581 ggatatcttg ctgatcaaac aaattgagct gaaatatctt tcaaagataa aaaaattact
     2641 atatttgttg gctgtggacg gaccgaaagc tccgaacgtg agccaactgg caagtgacgt
     2701 acagacatcc cgcgctacgg taatgaacta tatcaagtat ctggcagacg cgcgtctgat
     2761 taatctggtt tacccgaaag gagaagaatt cccaaagaaa ccgtcaaaga ttatgatgca
     2821 caactctaac ctgatgtact ccatttatcc ggtgaaagtg gaagaacagg atgtactcga
     2881 cacgttcttc gttaacactt tatggaaaga ccataaggta cataaaggag ataaaaacgt
     2941 ctctttcatg gtagacgaag tgatgccgtt caaaatttgt gcggaaggta caaaaataaa
     3001 gaataacccg gacgtgacgt atgcgttgca aaaggctgag ataggccgcg gcaaccaaat
     3061 acctctttgg atgttcggat tcttatacta aaaagattta tttacttaaa tatttaattt
     3121 agttatgact aaacagaaga aattcatcac atgtgatggt aaccaagctg cagcacatat
     3181 ctcgtatatg ttctctgaag tagcagctat ctaccccatc actccttctt cgactatggc
     3241 tgagtacgta gacgaatggg ctgccgcagg acgtaagaac atcttcggcg aaacagtatt
     3301 ggtacaggaa atgcaatctg aaggtggtgc tgccggtgca gttcacggtt ctcttcaggc
     3361 tggtgcattg actactactt acactgcttc tcagggtctt cttttgatga tccctaacat
     3421 gtacaagatt gccggtgaat tcttgccttg tgtattccac gtttctgctc gtacactggc
     3481 ttctcacgca ttgtgtatct tcggtgacca tcaggacgta atgtcagctc gtcaaaccgg
     3541 cttcgctatg ttggcagaag gttctgtaca ggaagttatg gatttggcag gtgttgctca
     3601 tctggctact atcaaatcac gcgttccgtt catgaacttc ttcgatggtt tccgtacttc
     3661 tcacgaaatc cagaagatcg aaatgttgga aaacgacgac ctcgctccgc tgatcgacca
     3721 ggaagctttg gctgaattcc gtgcccgtgc actgaatccg atgaagccgg ttgcccgtgg
     3781 tatggctgaa aaccccgacc acttcttcca acatcgtgaa tcatgcaata actactatga
     3841 agcagttcct gctatcgtag aagaatacat gaacgaaatt tccaagatca caggccgcaa
     3901 atacggtttg ttcgattact acggtgcaga agatgcagaa cgcgtaatta tcgcaatggg
     3961 ttctgtaact gaagctgccc gcgaagctat cgaccacttg gtagcaaacg gcgaaaaagt
     4021 aggtatggtt gccgtacact tgtatcgtcc gttctctgct aaacacttcc tggctgctgt
     4081 acccaagact gcaaagagca tcgcagtgct tgaccgtaca aaagaaccgg gtgctaacgg
     4141 cgaacctctt taccttgacg ttaaagactg cttctatggc gcagaaaatg ctcctgttat
     4201 cgttggcggt cgctacggtc tgggttcaaa agatacaact ccggcacaga tcatctctgt
     4261 attcgaaaac ttggctatgc caatgccgaa gaaccacttc actatcggta tcgtagacga
     4321 cgttacgttc acttctcttc ctcagaaaga agaaatcgct ctgggcggtg aaggtatgtt
     4381 cgaagctaaa ttctacggtc tgggtgctga cggtactgta ggtgccaaca agaactctgt
     4441 taagattatc ggtgacaaca ccgacaaaca ctgtcaggct tacttctctt acgactccaa
     4501 gaagtcgggt ggtttcactt gttctcactt gcgtttcggt gatactccga tccgttctac
     4561 ttacttggta aatactccga acttcgttgc ttgtcacgtt caggcttacc tgcacatgta
     4621 cgacgtaaca cgtggtttgc gtaagaacgg ttctttcttg ctgaatacca tctgggaagg
     4681 cgaagaactg gctaagaacc tgcctaacaa ggtgaagaaa tactttgcac agaacaacat
     4741 ctctgtatac tatatcaacg caactcagat tgcaatggaa attggtttgg gcaaccgtac
     4801 caatacaatc cttcagtctg cattcttccg tatcacaggc gtaatccctg tagatcaagc
     4861 tgttgaacag atgaagaaat tcatcgttaa gtcttacggc aagaagggtg aagacgttgt
     4921 taacaagaac tacgctgctg tagaccgcgg tggtgaatac aagactctga ctgtcgatcc
     4981 tgcttgggct aacctgccgg atgatgcaaa agcagaaaac aatgatcctg ctttcatcaa
     5041 cgaagtagtt cgtccgatca atgcacagga cggtgacttg ctgccggtat ctgcattcaa
     5101 gggtatcgaa gacggtactt ggtatcaagg tacttccaaa tacgaaaaac gtggtgtagc
     5161 tgcattcgtt cccgaatgga atgctgaaaa ctgtattcag tgtaacaagt gtgcttacgt
     5221 ttgtcctcac gcttctatcc gtccgttcgt actcgatgct gaagagcaga agggtgctaa
     5281 gttcgagcaa ctgaaagctg taggtaaagc attcgatggt atgacattcc gtattcaggt
     5341 agacgttctc gattgtctgg gttgcggtaa ctgtgccgac atctgtccgg gtaatccgaa
     5401 gaagggtggc aaggcattga ccatgaaaca ccttgaaagc cagttggccg aagctgataa
     5461 ctggacttac tgcgctgaaa acgtgaagag caaacaacac ctggtagaca tcaaggctaa
     5521 cgtgaagaac tctcagttcg caactccgtt gtttgagttc tcaggcgctt gctccggttg
     5581 tggtgaaact ccgtacgtga aactgatttc tcagttgttc ggtgaccgtg aaatggttgc
     5641 taacgctaca ggatgttctt ctatctactc cggttcagtt ccttctactc cgtacactat
     5701 gaacgaaaag ggtcacggtc ctgcatgggc taactccttg ttcgaagact tctgtgaatt
     5761 tggtctgggt atggaactgg ctaacgaaaa gatgcgtgcc cgtctggtga aagtaatgaa
     5821 cgaagctatc gcttctgatt gctgcccggc tgaatacaaa gaagtatttg ctgaatggat
     5881 caacaatatg ctggatgcag aaaagactaa ggaactggcc gaaaagatca ttccgatggt
     5941 agaagctgct aaagataaat gcaaccactg caagcaaatc gctgatctgc aacaatatct
     6001 tgttaaacgc agccaatgga tcatcggtgg tgacggtgct tcttatgata tcggttacgg
     6061 tggtcttgac catgtaatcg cttccggtaa ggacgttaac atccttgtat tggatactga
     6121 ggtttactct aacacaggtg gtcagtcttc taaagctact ccggtaggcg ctatcgctaa
     6181 gtttgctgct gcaggtaagc gtgtacgtaa gaaagacctc ggtctgatgg ctactactta
     6241 cggttatgta tatgttgctc agattgctat gggtgctgac caggctcaga ctctgaaagc
     6301 tatccgtgaa gctgaagcat atccgggacc atcactgatc atcgcttacg ctccatgtat
     6361 caaccacggt ctgaaagccg gtatgggtaa gagccaggaa gaagaagaaa aggctgttaa
     6421 gtgcggttac tggcacttgt ggcgttacaa ccctgctttg gaagaagaag gcaagaatcc
     6481 gttccaactg gatagcaaag aacctaactg ggaagacttc caaggtttct tgaagggtga
     6541 agttcgttac gcttctgtaa tgaaacaata tcctgctgaa gctgaagaac tgtttaaagc
     6601 tgctgaagaa aacgctaaat ggcgttacaa cagctacaaa cgtcttgcca gagaaaactg
     6661 gggagctgat acagctgaat aataagtaga aatactttgt acataataaa aggcaggaat
     6721 cctggaaaca gattcctgcc ttttttgttt atatcttaga agtaacgatt acttctcacg
     6781 aagatattca ttaaaactct aaagatatga tcggatttgt tatttggatt atcggtttga
     6841 tactgacttt cagagctgcc atagagattt ggaatataaa tgcggctgta gagaaaagac
     6901 ttatagcgat tgtattaatc gttcttacca gctggctggg actacttttc tactacttct
     6961 atggtaaaga aagaatggcg ggatggttga agtagtgttt gcatatcaat ctttctcagg
     7021 aatccaactg ttcaccagtt cctgatgttc ttccatccat tgacgggcag cctgtctttc
     7081 cgttgtctgc gcctcttcca gagcagtcat taaggagctg atttccgcat ctgtcagacg
     7141 aatgttgccc aaaagttcgg cagcaaaagg gtctttctcg ctaaaacctt tccatgctat
     7201 ggtatgaatg gattccgtat ttccatatat cagcttcggg tcctgaagaa ctttcagctt
     7261 gaaacggtcg aacatccagt gaggcgtcca tcccgtcacg acaatccagt ctttcttatc
     7321 aatcgctttc tttagggaag cagtcatggc aggtccgctc gaagtcatca gtttataatc
     7381 caatccatag tctttgatgg cctgatcggt agctttcata ataccggctc cggcatcaat
     7441 accgacaatc tgaccggaga aacgttcctt ttccgcgttc agttcttcga ttgagttgat
     7501 cgtaacgtaa tccggaacca ccagcccgat acgggcacca tcataaatat ccccgataac
     7561 ttcgagttta tccccgtatt gtttcatata atcttccata gtgacaggca tccagacatc
     7621 cataaatacg tctgctttct tacgggagat agaggtaaat ataggtgcaa ggtcggcatt
     7681 cagcaacttt acatcgtacc cctgatcttc aaaaatcgct ttggcaaggt ttgtcattgc
     7741 aataccttcc gaccagttgg cataagcgat acttatcttc ttactctttc cgttgtctcc
     7801 gcaggaaacg aaggttaaga gtatgccggc aataaacatt gccgcaatca tttttatctt
     7861 attcattgat tattcctttc tttggtgtga ttcttatttc tttttacttt ttctgttatc
     7921 tgccataccc tgagtgatgc ggtccagcac gatcgccaat atcacgactg cgataccgcc
     7981 ttcaaatccg agtccgattt tcatttgggt gatacctttc agcacgattt ctcccaatcc
     8041 tccggcagaa atcatggcag caatcactac catcgaaagt gacatcatga tcgtctggtt
     8101 gattcccgtc agaatagtag gcaacgccaa aggcaattgc accttataaa gaagctgcca
     8161 gggagtagct ccaaaagagc gggaggcttc tactacgttt ttaggaacct gacgaatgcc
     8221 cagaccggtc agacgaacca caggaggcat tgcaaagatg atggtggcaa aagctcccgg
     8281 cacagttccc aatccgaaga atagaacggc aggaatcaga tagacaaagg caggcattgt
     8341 ctgcataaag tcgaggacag ggcgcattat cttgttacaa cgatcactgt tggcagtcca
     8401 gattcccaac ggaacgccta aaagcaatgc cagacaagtg gaagaaagta ccaatgccaa
     8461 tgtctgcatc gtttcttccc aaaagcccat gccgtaaata agcaataaac ccaagagggt
     8521 aaatacggct gtccccttac ccgacttaaa ccaggcgagc gcagccagca ctgcaattgt
     8581 gatataaaaa ggtattccaa acagtacgtg ctgaaaaccg tctatgaatc ctccgatccc
     8641 catgctgaga gcatcaaaaa aggaagcaaa atgttctgtg agccaattaa tggcagtctc
     8701 tatatattgt ccgatattta tcataattct attgcgtttt gaatgatttc attaatttct
     8761 tctttatctt ttcccgttac ttcgatgatc aatgaggaaa gtggcactac gccttcaaac
     8821 tcccgattct catttacgac ccagattggc gagttcgttt ttgtcatcaa cggaagaata
     8881 tcttccagca ccgtatcacc cagcactgaa tgaacttcat gccttactac ggactcgatg
     8941 gagcggattt gctcttttcg tagtttcagc aagtcattca accgcacctc tcctactaac
     9001 agattattgg aatcgactac cggaagaacg gtcagattcc gttcgcgcat cttacggatc
     9061 agcacctccg ggccttcttt cttcaaacgt gccactatgg gtttatctac cataacagag
     9121 gaagctgtta taatcttgct tcgatctaca ttctccacaa atcgttctac ataagcgttg
     9181 gcaggttcgg tcaggatttc ttccgatgta ccgatttgta caatttctcc atccttcatg
     9241 atagcaatcc ggtcacccaa tttaatcgct tcactcaggt cgtgagtaat aaagacaatc
     9301 gtttttttca tcttcgactg caaagtcagc agttcatcct gcatctgcac acggatcaaa
     9361 ggatcgagtg ccgagaaggc ctcatccatc aacaggactt cgggattatt ggccaaagcc
     9421 cgcgccagcc cgacacgctg ctgcatccca cccgacagtt cacttaccat ctgattctcg
     9481 tagcctttca gccccaccag ttgcatactt tccatcgctt tctgctcccg ttctcccttt
     9541 tttactccct gtagttcgag cccgaaagct atattatgca agacagaacg gtgaggaagc
     9601 agaccgaagt tctgaaagac catagccagt tctttccggc gaatctgcaa cagttcctta
     9661 tccgacactt tggctatgtc tgttccattg ataatcactt ctccggaagt agggcgtatc
     9721 aaacggttga tgcagcggag taaagtggac tttccactac cggacagccc cataatgacg
     9781 aatatttcgc cttcattaat ggaaagattc gcatctttca ccgcaactgt acatccggtc
     9841 gctttcaata tttcactttt tgttttacct tctttcaaca tcttcaaagc cttctgcttc
     9901 tcattgccaa aaaccagata gagatcttta atttctattt tactcataca ataaaatggt
     9961 ttaggttatt aaaataatat acacagcaag acaagaacaa acgataacag gaatctttct
    10021 ttatatcgta taaagttctg atttaaataa gggacaaata acaatgaatc ccgaaataat
    10081 taataaaatg attattgaca gactgagtaa ttaaaaaagg aatagaattt gataagataa
    10141 tcctttcaac gaatagcaaa aaatagcatt tttatgtata aaaacagcct gttccagtat
    10201 cttgctggca caaagataca aaaaacggat taaacataca aattatattc aaaatccggg
    10261 gcatacagag ggctttattt gtaatgatat ggaaagtttc cgggtaatat tcccctatca
    10321 ctcagcaaaa tagaacaaac cggcagataa atataaaata agtttgaata tttcacttaa
    10381 acaccgtata tttggcgtca ataactaaac tagatttata tgttcaacag ggctattaca
    10441 attttcctgg ggaaggataa ttgtcattac acaacaaaag aaaaacaaac aggtactgcc
    10501 acactagacg acaaaagcca agtacagttc cttagtaaaa agaaccccaa aatgccgttt
    10561 ttctatagcc ggcggaatct ctacatgata ggtttcctgc tcgcttttat agtgactctg
    10621 ctcgaattta tacgaggacg gcatcaaaac tttatggtct tctcggacgc tactcaattc
    10681 ttctggcaag gcatcagccc atacacaact gaatttgtag aagctcacgg acgctacttc
    10741 ctttattctc cagttttcac ggtattgttc gctccgtttg cgtatctgcc tgcatggctg
    10801 ggacctttcg cgtggaatct attcaattat tcgctgttct ttatggcgat cttcacgctg
    10861 ccccaacaat tcacccagca gcagaaatgc cgtatgttcc tttttctgtt actgatttta
    10921 ggacaaagtt tactttcatt tcagtataac ataacggtag cctatttatt cttattcgcc
    10981 tatacgttat tggaaaaaga ccgtggattt ctggctgttc tgttaatcat gatttcggga
    11041 tgtaccaaag tatatggaat tttcgaactg gcattgttgc tgtgctatcc tcacgtatgg
    11101 cgtaactttg gctatgccgt tacaatgggc attgtattgc ttgcattacc gttaatcaaa
    11161 atagctcctg cagatttgct cccctattat gaagaatggt gccatagtct tgctgttcat
    11221 cagtccgccg gagcttatga ttcatttttc tatgcccgcc ccattgcagc atggacattg
    11281 ccacacttcc gtgcacttca gataggaatg ctcggcttgc tgactctgct ctttttgggg
    11341 aatttccgca aatggtcgtc ttttgccttc cgtgcccagg ctttgggcat tctcatgggc
    11401 tgggtagtat tactgagtga ctccgccgag aagcatacct atattatcgc attggcaggt
    11461 ttcatgctct ggtattggag cagaccaaca cgtaccgcaa cagacaagat tctattttgg
    11521 tgctgttttg tgctgttatg tatcgttcct atcgacatat tcgtccctat acccatcaga
    11581 gatttcatta ccaggacctt atggcttcat gtatgggttt tctttattgt atggatacgg
    11641 atgatatggc ttaccttcct tgcatccttc attcatccac gtgccacaaa tgttctttca
    11701 gattaacgca tccgttagct ttgaaagaaa cttcttctgc cagcaagagt tgtttttgtt
    11761 ccacccaacc gggcaccagc cttccggtgg aatttacaac tctatggcag ggaatggata
    11821 attcatccgg cacttctttc aatgcacgtc ccaccatccg cgagcattgg ggtgccccca
    11881 acagcaaagc aatacctcca taagtagata cttttcccac aggtatctgg gatacgactt
    11941 cgtacacttc cttccgaaag gattcggaaa agctctcttt atctacttta taatctttca
    12001 tatatccctc tttacgatat caatgaaatc atcctttcct tttcaggaaa tctgtcgggc
    12061 tctctccaaa ctgctcttta tagcacttgg cgaaataaga aggtgaactg aaaccgactt
    12121 cataaccaat ctccgctacg gtcatgtccg aagaagcaag caaagaagct gccttcttca
    12181 aacgggcgat acggagcaat tcattcggag agtagttagt caatgattta atcttgcgat
    12241 aaagctgcac acggcttagt cccatgtctt tgcccaagtc ctccacattc aaaccggagt
    12301 ctcccatttt ctcttcaatc aatgacttga atctttctac aaaatccttg tccatatcgc
    12361 agacatcttc ttttgccaat gtctgcccgt caccaaagaa ctgtttcaga cgacggtgag
    12421 aatcgatcag attgcggaca cgtgccagca acagctgtga actgaacggc tttgaaatat
    12481 aagaatccgc accaccgtca tatccctgaa tacgctgttc gtccagtgaa cacgctgtca
    12541 gcagaataac cggaatatga caggtctgta actcactttt cagccggcgg caacattcaa
    12601 tgccatcaat gcccggcatc atcacatcag aaatgatcag gtccggaaca tacttcatag
    12661 ccttacggat tccttcggag ccgtctgccg cttcaatcac cgtatagtct gtatgcaaca
    12721 acgtatggac atacgaacgg atatcctcat tatcatcaat aatcagtacg gacggtttgg
    12781 aagagtcata tcctttttcc agttcttcct cttccgccaa tagaacatct gttgtacggg
    12841 aatccgcaga aacaagggtg gtatccggtt cggcagcaac agcctcacaa gactgtacag
    12901 gcagttcaac ggtaaagacc gtgccctgtt tctcatcgct ctctacggag atcataccac
    12961 cgtgcatttc tacgaaggct tttaccaatg ccagtccgat tcccgaaccg gtatggtgca
    13021 tatcgatctt atagaaacgg tcgaatacat tgcgaatatg ttcggcagaa atcatagaac
    13081 cggtatttgc caccgtgaaa cgtatccatc gcttgtcctc tttactaagg gaagacagac
    13141 ggacggctat tttcccgttt tccggtgtaa acttaaaggc attggacaga agattgaaat
    13201 aaatacgttc cagcttctcc atgtctgcca gtgtatgata atccgtatcc ggcatactat
    13261 caaaagaaaa atggatatgc ttcttacggg ctgccgcctg aaaagactca ttccatcctt
    13321 cgaaagaaga aaggacatcc accgtaaccg gagtatattc catcttgccg ttttcatatt
    13381 tacggaaatc cagaatctga ttgaccagac gcagaagaat gttcacattc cgctgaatca
    13441 gcatgagcat ccggtgctga tctccgctca gtgtcttgtc cgccaacaaa tgttctaccg
    13501 ggtcggcaac caatgtcaac ggagtacgga agtcgtgaga aatattggtg aaaaagacca
    13561 gcttggcatg ggtagcttct tccagttgat gagagagctg tatcaattgg tcacgctgtt
    13621 cttccagttt gtcacgctgc tcttccaatt gctgcttctg cttaaaaagc tctttattca
    13681 agcgattctt agagcggagt gatttataaa cgaccaataa taagccggct accaataaaa
    13741 ggataatcag actgccgtat aaaacgacct gttgtgtagc tacctgagag agatagccac
    13801 cgatacgtcc gttgagcgtt tcaatctttt tgtcgagttc ggaaatgtgt gtggtctgca
    13861 actgcatgac gtgtgcgttg gtacggtcca caacagcggt attcatcacc gtttctttgg
    13921 gatagggttt cttctccaga atgtccatag ccagttgcag taccttatcg ccattggtcg
    13981 gatagataaa ggtggcatcc agcacactgt ccagtaccag ttccagtccg tttcccttac
    14041 ccggcaaggc atctatgccg acaaaaatca tttccttctc ccgccctgcc atctttgctg
    14101 cctgataggc acccggagcg atacggtcat tatgggcata cacagcatca atcttaggat
    14161 gcctccgaag catactatcc atttctatct ctgccggacc acgttcccac gcagcatccg
    14221 ctttatcaat cagctttata tccgggaatt tactgatggc agccataaat ccctgatgcc
    14281 gttccattgc aggagtcgaa ccgctcaatc ctgtcagttc tactatattt cccttccctt
    14341 tcagactgga ggcaatatag tttcctaccg aacgaccgat ttcataatta tcggctccga
    14401 tataggcagt atatttatcc gaaagaatct tccggtctac aagaataacg gggatgcctt
    14461 tctgataagc ttcttctaca atcggagtca taggagcagc ttcgttagcg gaaataatca
    14521 gcagatcgac tccttcgtcc ataaaataat ggacatcttc cgcctgctta ctgttatcat
    14581 cccctgccga acggatttcc accgaaacac cattataaaa catcgcttcc cgaagaatct
    14641 catcattcat cttatgtcgc catgaatcat cgctgcattg agccacccca atacgaaaac
    14701 ggggtgtatc ctgccggcaa gccgtcatcc cgattaaacc aaacagcacc agcatccact
    14761 tcagatatct catcgtcttc atccatctca tcatttcata gttctttctg taatccaatt
    14821 aagaacaaaa ataagaaata atactgtaaa gttctctaac ttcagctatt tattattcta
    14881 aaaagaagga aagcagtcct ctttcagacc atcggaaagt attaacaaaa gtataaagcg
    14941 taaaacaaac acttaatcaa tgttataaaa catagcgttt tacttggata atttgcagat
    15001 ttcacagaag tccgtatctt tgcactgtgt ttttcatagt attagattta aggttaacaa
    15061 aggttggagc aaggcgttgc tccttttttt atgctctgac ctttcatcta ccggttagtt
    15121 ttcatcccat tccttttcca gtttaccatc aatagtgtag cgtttccatc gtcctacacg
    15181 gtgaccattc ttatattccc cacattcacg aagctggtca ttctttacat aacgagcttc
    15241 gaacggtccg ttctgccttc cgttcacata ggtagaagtt tcccaataat caaagcggtt
    15301 gctcactatc agccgtcgtt ccttgccatg caatctgccg gcctgatagg tagcttcata
    15361 tctcaattca ccattttcca aattatattc acggtataaa ccgtctttac gatcgttctt
    15421 catataatat tctttctgcc ttaccccact tccgttggca aatgagacat ggagtccatc
    15481 ttcttttcca tccagatagg tttcaatcat cagcgtatct ccgctttcag caaaagtagt
    15541 ccaacgacca ttcttctttc cattcttata actacccagt atacgtggcg agccaaacgt
    15601 aaacacggac gaatattcac cgtcctgaaa accttcttca ttgaaataaa cggtctcata
    15661 caaatcatat gtacctttca gaaaagtata ctgtttgcct acctgcttcc cgtccttgta
    15721 attatgctct ttccgcaaag taccgtcaga ttcgtacgac agttgcttcc cgtgctcttt
    15781 ccccatccgg aagtttcttt cactttccac ttttccggta ataaagtaac ttttgctcgt
    15841 accgtccagc ttaccttcct tataggactt ttcttctttc agcttaccgt caaacttgga
    15901 gttaatcttg aagaggccat ccttccgccc ttctttataa cttccttccg ttattaatat
    15961 attgtccaca tattctttgt atccgccatc ataaaaacca tctttaaaag atgccagcac
    16021 ataggcggaa tgataaccat ctatgatgcg atgttcgcca ttcaatgctt tttccgtttt
    16081 cagttcctga aacaacagtc tgccatcgcc tacattaaca acagatacct gatcgatctt
    16141 atattccttt tgcgcaaaca aaggaagagc aagatataaa aacaaaaata cgttccagct
    16201 ttttgatctg aggaagttcg aaatgtgttt cataaagtag ttttctcttt ttgatttatt
    16261 atttaaaaac ctgccgcaaa gataggcaat cggcttataa aacaaggcaa gaaagagggg
    16321 gacaattaga aaaaagaaca tctgttatta tcattctaat aattaacaga ttaagtagta
    16381 aatcaaaaca cagggaaggg ggacatttac tgaaataaga aacagaaaag aagatgtgtc
    16441 aaaagcaact aaattcccct ccttcag
//
