LOCUS       c00021_gnlPro..        32782 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LIPNJIEB_21.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 05:38:41
            Original ID  :: gnl|Prokka|LIPNJIEB_21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 32782
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..32782
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7526:22782]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7527..22782
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..32782
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..32782
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             134..352
                     /locus_tag="ctg21_1"
                     /transl_table=11
                     /translation="MIEFKIRAYGRMELAQLYSPELTGIAAYRKMNKWIVRCPGLQERL
                     SDLGYQPQHRSYTPLEVRVIVDALGEP"
     CDS             complement(572..2410)
                     /locus_tag="ctg21_2"
                     /transl_table=11
                     /translation="MTDIESLRLLTEAVETAGADIAPTYAEYVQLAFAIATDCGEAGRE
                     FFHRLCRISAKYQSAHAERMFSNALTKQQGAIHLGTAFHLAESTGVKICREDRKEVMNN
                     RTGTVGTESSPHNFSTHAHVYNKVEEEKSESEELLEGSDPHHPLPTFTLEDWPKLLLRI
                     ISYGTTATQKDVLLLGALTALGATMERYVRCHYAGKYQSPCMQSFIVAPAASGKGVLSL
                     IRLLVMPIHDDIRQQVEKEMNVYKKAKVAYEMMGKERAKAEIPEIPLNRMFLISGNNTG
                     TGILQNIMDNNGTGLICETEADTISTAIGSEYGHWSETLRRAFDHDWLAYNRRTNQEYR
                     ENKKSYLSLLLSGTPAQVKPLIPSVENGLFSRQLFYYMHGIYQWINQFDENETDLEAIF
                     TSIGLEWKKLLNLLKEHGLHTLRLTDEQKQEFNDLFSELFTRSTIANGREMNSSIARMA
                     VNICRIMSVVAMLRAFENPQPYQYQASSHPLLTPDKEIATDNIKDGIITRWDMTITPED
                     FKAVLNLVKPLYQHATHILSFLPPSEVSHRANADRDAFFEALGIQFTRAQLLEQATTMG
                     IKPNTALTWLKRLVKQGLIVNLDGKGTYAHARVCVC"
     CDS             complement(2477..3103)
                     /locus_tag="ctg21_3"
                     /transl_table=11
                     /translation="MQNFFRMSYFMPPIAPIRNEQGQTVTPATLTPFCEVSVEQVYQMI
                     TCNENLKALTEQVRSAEDIRMAKTSLLPYVTPCGTFIRRNSKFFASPSGLVVVDIDNLD
                     SYQKAVEMRRTLFDDPFLHPVLAFISPSNRGVKTFVPYSNLYTDDQSRNVRESMSWAME
                     YVEMTYGSEMNNSIETVQKAVDTSGKDIVRACFLSHDPQALFREY"
     CDS             3257..3406
                     /locus_tag="ctg21_4"
                     /transl_table=11
                     /translation="MENKIVHPKLGEFIEKVLKVAHVNLSKMCQEIHMGPATYQKVKKG
                     KKKL"
     CDS             3571..5133
                     /locus_tag="ctg21_5"
                     /transl_table=11
                     /translation="MEDLQRLYPIGIQTFSKIREGNFLYVDKTEYVYRMTHSASSYMFL
                     SRPRRFGKSLLTSTLHSYFSGREELFRGLAMEKLEKEWIQYPVLHFDMSMAKHVDKDKL
                     MNLLDFMLTEHERTLGIDAAGTDPNLRLTNLIKRAYEQTGRKVVVLIDEYDAPLLDVVH
                     ERENLGVLRDVMRNFYSPLKACDPYLRYVFLTGITKFSQLSIFSELNNIKNISMDEPYA
                     AICGITENEILTQMKEDVDRMAVKLNITAEEVLAKLKENYDGYHFTYPSPDIYNPFSLL
                     NAFADGKFNSYWFGSGTPTYLIKMLDKFGVEPSEIGNKLAAVEEFDAPTETMSSITPLL
                     YQSGYVTIKDYDKELELYTLDIPNKEVRVGLMRSLLPYYVTNDTREATNMVAFISRDIR
                     KGDMDAALRRLQTFLSTIPQCDHTKYEGHYQQVFYIIFSLLGYYVDVEVRTSRGRVDVV
                     LRTEATLYVMELKLDKNATVAMEQINLKNYPERFALCGLPVVKVAVNFDSESGTLGDWM
                     IEK"
     CDS             5409..5669
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_gamma"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_6"
                     /sec_met_domain="OAD_gamma (E-value: 8.4e-14, bitscore:
                     44.1, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENIETAILLMVVGMATVFVILLIVIYLGKLLITLVNKYAPEEVI
                     PAKKEALQGPAPIPGNIMAAITAAVNVVTLGKGKITKVEKL"
     CDS             5698..7527
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 59.8; E-value:
                     5.7e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_7"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.8e-19, bitscore:
                     59.8, seeds: 40, tool: rule-based-clusters)"
                     /sec_met_domain="HMGL-like (E-value: 7e-21, bitscore: 66.9,
                     seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 4.8e-25, bitscore:
                     80.5, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKREVKFSLVFRDMWQSAGKYVPRVDQLVKVAPAIIEMGCFARVE
                     TNGGGFEQVNLLFGENPNRAVREWTKPFHEAGIQTHMLDRALNGLRMSPVPADVRKLFY
                     KVKKAQGTDITRTFCGLNDVRNIAPSITYAKEAGMISQCSLCITHSPIHTVEYYTNMAL
                     ELIKLGADEICIKDMAGIGRPVSLGKIVANIKAAHPEIPIQYHSHAGPGFNMASILEVC
                     EAGCDYIDVGMEPLSWGTGHADLLSVQAMLKDAGYQVPEINMEAYMKVRALIQEFMDDF
                     LGLYISPKNRLMNSLLIGPGLPGGMMGSLMADLESNLESINKYKAKHNLPFMTQDQLLI
                     KLFNEVAYVWPRVGYPPLVTPFSQYVKNLAMMNVMAMEKGKERWGMIADDIWDMLLGKA
                     GRLPGTLAPEIIEKAEREGRKFFEGNPQDNYPDSLDKYRKLMKENKWEVGEDDEELFEY
                     AMHPAQYEAYKSGKAKEDFLADVAKRRAEKDKSPEEDAKPKTLTVQVDGQAYRVTVAYG
                     DAELLAAPVAAAPAGEGKDVLSPLEGKFFLVKNAQESALKVGDAVKEGDVLCYVEAMKT
                     YNAIRAEFSGTITAICANPGDTVSEDDVLMKIG"
     CDS             7527..8762
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_8"
                     /sec_met_domain="OAD_beta (E-value: 1e-142, bitscore:
                     467.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEIFENLYDMTAFSNIIAEPQFLIMYAIAFVLLYLGIKKQYEPL
                     LLVPIAFGVLLANFPGGDMGVIQADENGMVMINGVMKNIWEMPLHDIAHELGIMNFIYY
                     MLIKTGFLPPIIFMGVGALTDFGPMLRNLHLSIFGAAAQLGIFTVLLVAILMGFTPQEA
                     ASLGIIGGADGPTAIFTTIKLAPHLLGPIAIAAYSYMALVPVIIPLVVKLFCTKKELSI
                     NMKEQEKKYPSKTEIKNLRVLKIIFPIVVTTIVALFVPSAVPLIGMLMFGNLVKEIGSN
                     TFRLFDAASNSIMNAATIFLGLSVGATMTAEAFLNWTTIGIVIGGFLAFALSITGGIFF
                     VKLVNLFSKKKINPLIGATGLSAVPMASRVANEIALKYDPKNHVLQYCMASNISGVIGS
                     AVAAGVLISFLA"
     CDS             complement(8878..10158)
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="MKEMKTQLILFSLLLLGSTAWAQQPCLSQDAYREKVEAYSQILKQ
                     QKLKTLASSEARKIAHTGFLPKIDVNADGTLNMSDLSAWNEPVGEYRNHTYQGVFVVSQ
                     PLYTGGALNAQHQIAKADEKLNQLNEELTLDQIHYQSDAVYWNASASKAMLQAADKYQS
                     IVKQQYDIIQDRFDDGMISRTDLLMISTRLKEAELQYIKARQNYTLALQQLNILMGEAP
                     NTPVDSLYNIGMISAPVRILPLEDVLQRRADYASTEVNIMKSQAQRKAALSQFNPQLNM
                     YFSGGWATATPNLGYDVSFNPIVGVNLNIPIFRWGARFKTNRQQKAYIGIQKLQQSYMT
                     DNINEELSAALTKLTETESQVKTAKENMSLANENLDLATFSYNEGKASMVDVLSAQLSW
                     TQAHTNLINAYLAEKMAVAEYKKVTSE"
     CDS             complement(10201..13239)
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MNLAKYSLDNTKIIYFFLAVLLIGGITSFGKLGKKEDAPFVIKSA
                     VIMTRYPGAEPAEVERLITEPISREIQSMSGVYKIKSESMYGLSKITFELQPSLSASSI
                     PQKWDELRRKVLNIQPQLPSGASTPTVSDDFGDVFGIYYGLTADDGFTYEEMRNWAERI
                     KTQVVTADGVMKVALFGVQTEVVNIFVSTNKLVGMGIDPKQLANLLQSQNQIINTGEIR
                     AGVQQLRVTANGMYANIDDIRNQVITTKAGQVKLGDIAVIEKGYLDPPSNIMHVNGKRA
                     IGIGVSTDPQRDVVQTGENVKVKLNELLPLMPVGLELQSLYLENEIANEANNGFIINLI
                     ESILIVIVIIMLVMGLRAGLLIGSSLIFSIGGTLLIMSFFGVGLNRTSLAGFIIAMGML
                     VDNAIVVTDNAQIAIARGVNRRKALIDGATGPQWGLLGATFIAICSFLPLYLAPSAVAE
                     IVKPLFVVLAISLGLSWVLALTQTTVFGNFILKAKTGDSTKDPYDKPFYHKFAFVLGVL
                     IRKKAVTLVSMVILFIISLIIMGTMPQNFFPSLDKPYFRADVFYPDGYSINDVVKEMKS
                     VEEHLAKQPEVKKVSITFGSTPLRYYLASTSVGPKPNFANVLVELTDSKYTKEYEEDFD
                     GYMKANYPSAITRTSLFKLSPAVDAAIEIGFIGPNVDTLVSLTNQAIAIMHQNPDLINI
                     RNSWGNKIPVWKPVYSPERAQPLGVSRQGMAQSIQIGTTGMTLGEYRQGDQVLPILLKN
                     NQLDSFRINDLRTLPVFGTGNETTSLEQVVSEFDFQYRFSNVKDYNRQMVMMAQCDPRR
                     GTNAISAFNQVWSQVQQEIKIPEGYTMKYFGEQESQVESNEALAKNLPLTFFLMFVTLL
                     FLFKTYRKPTVILLMLPLIFIGIVLGLLVLGKSFDFFSILGLLGLIGMNIKNAIVLVDQ
                     IDLETAAGKKPLDAVISATTSRIIPVAMASGTTILGMLPLLFDAMFGGMAATIMGGLLV
                     ASALTLFVLPVAYCAIHRIKGEQ"
     CDS             complement(13236..14288)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_11"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 7.3e-12,
                     bitscore: 37.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIYVIALAAILFQGCGQKKEMTAPATRPVKTTIVESRSVIRKD
                     FSGIVEAVEYVKLAFRVSGQIISLPVIEGEKVKKGQLIAAIDPRDIALQYAATKSAYET
                     ASAQVERNKRLLSRQAISVQEYEISLSNYQKAKSEYELSSNNMRDTKLTAPFDGSIEKR
                     LVENYQRVNSGEGIVQLVNTQNLRIKFTIPDAYLYLLRAKDPRFLVEFDTFKGHVFKAR
                     LEEYLDISTEGTGIPVSITIDDPSFDRDLYAVKPGFTCSIRFTADVGPLVQDSWTIIPL
                     SAVFGESDGNNMYVWVVEDNKVHKRKIVVNAPTGEAQVLVSEGLKPGEQIVIAGVYQLV
                     EGESIKSIDK"
     CDS             complement(14934..15188)
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSKSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             15589..16593
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAE"
     CDS             complement(16673..18007)
                     /locus_tag="ctg21_14"
                     /transl_table=11
                     /translation="MKRIILLAFLCTTTLVMAQRINHVQEAIANYDYEAALTLIAKEKP
                     TIPLLLQKGKAQRGLGMNTEALSTYQEIITNDTANTRAYIEAAECCRSLAKYQQALKYY
                     EQALDLNPENKYVRIQYIGLLLSLQKFQDALGESSLMTEKDSSAIALHLQAQSFEGMGE
                     LLPATGCYYNIQEKYPDDYLAAAKLAALNIAGSYFNEAIEATEKYRQIDTTNIAVNRQN
                     ALAYCLNKDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAEEKYYEAHDFLEAARKHDP
                     ENVNLLYYLGRACAKTSWKKLGVEYLEKALDLTIPKDSNMVRLYIGMTDCYKMAQMPKE
                     QIESIRERYRKYDKQNHKLLYDMAFIYFYSLKDKKNTERCLEAFLKTRPKEDKEEEAKL
                     NERGELVLGTKNYYNAAANWLKDIQSKQKIEDFFLGGNVPAQKPE"
     CDS             complement(18221..19381)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_15"
                     /sec_met_domain="OAD_beta (E-value: 6.8e-153, bitscore:
                     500.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATGGHIAMIIIGLGFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(19383..19817)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.7; E-value:
                     4e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_16"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.1e-21, bitscore:
                     66.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKAT
                     PKPAVVRPMPNSPAAPTTPVVKPAAPSTGKSGVKSPLPGVILDIKVNVGDTVKRGQTII
                     ILEAMKMENNINADKDGKVTAINVNKGDSVLEGNDLVIIE"
     CDS             complement(19842..20762)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_17"
                     /sec_met_domain="OAD_gamma (E-value: 1.8e-14, bitscore:
                     46.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLLLNEVLIDNQNNFQD
                     DYGLHSAWIEIFNKSYGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGRKLLDQVVIPAGTLGPNQSYARISDGAADW
                     EVKGGSKDKYVTPSTNNKTLDSNAKMEKFEEHDSVGIGMSISAMSVVFCGLILLFIAFK
                     VVGKVAVNLSKRNAMKAKGIDKVEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRENPNRK"
     CDS             complement(20794..22347)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_18"
                     /sec_met_domain="CT_Btheta (E-value: 2.1e-290, bitscore:
                     955.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYLFAQDFTVTAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGLALIRTLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPN
                     KPYDMYEVISAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKFLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(22378..22782)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_19"
                     /sec_met_domain="Glyoxalase_4 (E-value: 6.7e-24, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(22956..23954)
                     /locus_tag="ctg21_20"
                     /transl_table=11
                     /translation="MPLKLTTYYRGKDIPDLPGTNTFHSKELFQIYESTPGYTPLLIVA
                     TEEGRPVARLLAAIRKTKKWLPSSLVKQCVVYGAGEFLDTSLPASKEKEEEIFGEMLEH
                     LTQEASRTCILIEFRNLDNSMFGYRFFRKNDFFPVNWLRVRNSLHSTQKAEDRFSPSRI
                     RQIRKGLKNGAKVVEAHTVEEIKEFSRMLHKVYSSRIRRYFPANDFFRHMNSMLIRGKQ
                     AKIFIVKYKEKIIGGSVCIYSGENAFIWFSGGMRKTYALQSPGILAVWKALEDAHERGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRISWPWLNNLLVKFYV"
     CDS             24203..27397
                     /locus_tag="ctg21_21"
                     /transl_table=11
                     /translation="MRENAFVEAWKTQHRRVSMILGLTLLCAPSAISVYAENGVNDITV
                     QAVMQTKTVKGTVLDENGEPLIGVSIVVKGTSTGTITDFDGKFSINLPGGSKELVVSYI
                     GYKEQAIIVSGNAPLNIKMVPDTQALDEVVVIGYGTVKKRDLTGAVASVKSEDITMNPG
                     VNPMDALQGKIAGLDITNSSGQAGSSPTVQLRGTRSLQLDEDGNISSDAFKPTYIIDGM
                     PGDIATLNPNDIESIEVLKDASSTAIYGSSGANGVIIVTTKGSKSGKPVINFNAYAGTT
                     MGARVPKMRTGDSYINYIKDSYKPVGTTNEEEIFGERYDAIKNNQWVNWGDEVLHSGLK
                     QNYSISVAGGTEKTKAYFSLNYTDEKSMYENDDYKVYSTRVRIDQEINKWMNAGINVQA
                     SFSNKNSRNAVLERALFATPLGVPYNEDGSITEFPIPGSSSDPNPLADEQDGVYKNNTK
                     AGRAYVDAYLEWKPVKGLSVKSQLGGSYSQSRAGKFMGEGSYNVLKGSTVAYGEATNKT
                     GYNYKWENIVTYHNTFNKDHDLTVTGVTSWNYNQSEEYYVYGENPATNDMLWYALQNAD
                     NKKLNSKYLMSKGMGFIGRVNYSYKGKYLFSASSRYEADSRLSKDNRWNLFPAVSVGWR
                     ISDEAFMAGTKSWLDNLKLRVGYGVAGTTAGIAEYSSMASLENVTTSLGGMTVPSAKFT
                     EYITNRNLTWEKTHDLNIGIDASFLNNRIDLTVDLYRTKTTDVILSQALPTSIMGNYTG
                     STTYKMNKNAAETENRGIELALNTRNIVKKDFTWSSTVTFTANKEKIKSLIEGQDMMFN
                     AKKGDMVFKVGEGVGSFYRYKVLGIWQYSEKETAALFGCEPGDIKLDLPSVKKDGNGYY
                     YMNPEGERVDITAENPYGVRADYDRQVIGRNTPDWTLGFKNNFRYKDFDLSVFLYARWG
                     QMMNYGSVIGKYSPNPDYNIPTYFTYYDKTIEADQNVLFYAIDKSKDRSAYEGYDSMYY
                     VDGSFFKLKNVTLGYTLPGKLTKRFGISNLRVYATMTNLFTYSPNKYVKNYDPEMNGSI
                     NFPLSRDCIFGLNLTF"
     CDS             27409..29364
                     /locus_tag="ctg21_22"
                     /transl_table=11
                     /translation="MKKIYSLVLLVAGVFSWGSCSLDEVNPNNSGQFSDGSYTLETYKA
                     FTNSCYTALINNIYQSSDYLVCTEAGTDIWEEPKSGSSYQRYHSYNGMKTDDSYYYKVW
                     QYSYLCINSCNIVIDGAENVTGDENEINECVAQARCLRAYYYMNLVEQFGNVDLQLKAA
                     DSENISFDAHRSTVPEIYAAIIEDLKFAVENLPVSFSDYYSRVTKKSAMGLLARAYING
                     AGYDLKDIDGVSFLEKAYDTATTMINNKAIYEWYMHPAFADVFNENNNRNNEEALFIAA
                     GAERNSDAYTNGNYSQSEMFRHFLPSLGTYTDLGLVDKTSNFVYGRPNSNIFLPSKYLM
                     DCFAADMNDSRFRYSFISAYSSYSIPAWGATYEYGGSACAKEITSTLATKFGIPASNIG
                     KKVYPHFNLESNSTADANYCQLAIWNADGTAKTTQDKTDGNILHPAMPLDPAEAHQYAV
                     YCSLKTLTEEEKAQYPGLVLNVFDLYDENGTARATYDKPSAASALWLSIYPALSKFNMP
                     GNKFVGRDVQRKTVDVMIMRMAEVYLIAAEASVRLNKGDAAKYINVLRTRAGAGTVSES
                     QVDLNYIFDEYARELCGECGRWYLLKRNAAFETRLAAYNKRAAEHFKKEFYLRPIPTKY
                     LDAINNPAEFGQNAGY"
     CDS             29551..30093
                     /locus_tag="ctg21_23"
                     /transl_table=11
                     /translation="MIEEMLAYNREFVKNEGYKEYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EEMLEKMKARGINADYIHMMSFCGVDFHSWLDGFEDTEKSVRGTVDFIVHHPLIPSDVK
                     VHGFIIDSTTGELTRIV"
     CDS             30309..31028
                     /locus_tag="ctg21_24"
                     /transl_table=11
                     /translation="VSVLFDFCLTAGFTIRFDVIVLCNSFFHNEYISQCKDTISFLITI
                     GLRYLCIHKSNENGNNMENFSELIKNRRSMRKFTDEELTQDEVVALMKAALMSPSSKRS
                     NSWQFVVVDDKEKLKELSHCKEQASSFIADAALAIVVMADPLASDVWIEDASIASIMIQ
                     LQAEDLGLGSCWVQVRERFTATGMPSDEFVHGILDIPLQLQILSVIAIGHKGMERKPFN
                     EEHLQWEKIHINKFGGK"
     CDS             31031..31366
                     /locus_tag="ctg21_25"
                     /transl_table=11
                     /translation="MGAVKANNNKDTYKATAVAFIVIGTLFLINKLLPFASIGLPWVMN
                     KDNLLLYASISFLIFKRDKSVGFVLLGLWLVMNIGLVMSLLGSLSGYLLPLALLIIGII
                     LFWVSKR"
     CDS             31374..32168
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Shikimate_DH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_26"
                     /sec_met_domain="Shikimate_DH (E-value: 2.7e-10, bitscore:
                     32.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="F420_oxidored (E-value: 1.5e-12, bitscore:
                     40.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPVVFLGAGNLATNLAKALYRKGFRIMQVYSRTEESAR
                     TLANEVEAEYITDLKGVSNEARLYIISLKDAAFVELLPQITDGKQHALLVHTAGSIPMN
                     IWEGHAERYGVFYPMQTFSKQREVDFREVPFFIEAKRPEDAELLKAVAGTLSDKVYEAD
                     SEQRRSLHLAAVFTCNFTNHMYALAAELLEKYHLPFDVMLPLIDETARKVHELAPRDAQ
                     TGPAVRYDENVMNKHLSMLADSQALQEIYKLMSKSIHEHHQL"
     CDS             32149..32670
                     /locus_tag="ctg21_27"
                     /transl_table=11
                     /translation="MSTINYDLSRIKALAFDVDGVLSSTTVPLHPSGEPMRTVNIKDGY
                     AIQLAVKKGLHIAIITGGRTEAVRIRFAALGVKDLYMGSAVKIHDYRDFRDKYGLSDDE
                     ILYMGDDVPDIEVMRECGLPCCPKDAVPEVKSVAKYISYVDGGRGCGRDVVEQVLKAHG
                     KWMAEDAFGW"
ORIGIN
        1 gaatcggttg tgtacagtga gagtcggtaa tgtgcaattg ttgtcagtta tagtctgtta
       61 ttccctgata aaacgtaggt aatgtgaata tattttgtta cttttgtgac agtaaaacag
      121 aaacttattt gtcatgatag aattcaaaat acgtgcttat ggtcgtatgg aactggcaca
      181 gctttattct cccgaactta ctggcattgc cgcttaccgc aaaatgaata aatggattgt
      241 ccgctgtccc ggtcttcagg aacgcctgtc cgatttaggt tatcagccgc agcaccgttc
      301 ttacactccg ctggaggtaa gggtgattgt ggatgcattg ggagaaccat gagcaggtaa
      361 taagtattag gtaacaggta ataagtgttg tagactgcga ggggcgtttt gtattagcta
      421 aagctaagct ttagaggcca taaagcaccg ctttagaagt cgtaaagcat agctttagcc
      481 aatacaaaac gctatactct gattttcata aagaaacgat aaaagacgat gttatcaaca
      541 ggtacagtag gtacactttt ccggcccttc cctaacacac gcacacgcgt gcgtgcgcgt
      601 aagtaccttt accgtcaaga ttgacaatca gtccctgttt taccagtcgt ttcagccagg
      661 tgagggcagt gttgggcttg attcccatag tcgtagcctg ctccaacaac tgtgcacggg
      721 taaattggat acccagtgcc tcaaagaatg cgtcacggtc ggcattggcc ctatggctga
      781 cttctgaagg aggaaggaaa gacaagatat gcgtggcatg ctgatagagt ggtttcacaa
      841 ggttcaacac agccttaaaa tcttcgggag tgatcgtcat atcccaacgg gtaatgatac
      901 cgtctttgat attatcagtg gcgatttcct tgtccggtgt aagcagggga tgagaagatg
      961 cctggtattg atacggctga ggattttcaa aagcacgaag catggccact actgacatga
     1021 tacggcagat gttgacagcc attcgggcga tggaactgtt catttctctg ccattggcaa
     1081 tcgttgaccg ggtgaacagt tcggaaaaga gatcattgaa ctcctgtttc tgttcatctg
     1141 tgagccggag tgtgtggaga ccatgttcct tgagtaagtt caagagcttt ttccattcca
     1201 gaccaatgga ggtgaagatg gcttccaagt ccgtttcgtt ctcgtcaaac tgattgatcc
     1261 attgatagat gccgtgcata taatagaaca gctggcgtga aaaaagtccg ttctctactg
     1321 aaggaatgag tggtttcacc tgtgcgggtg tccccgaaag caggagagag aggtaacttt
     1381 tcttgttttc ccggtactcc tgattggtac gtcggttgta tgctaaccag tcatggtcga
     1441 atgctctgcg aagcgtctca ctccagtgac cgtattccga accgatggcg gtagagatcg
     1501 tatccgcctc ggtttcgcag atgaggcctg ttccgttgtt atccataata ttttgaagga
     1561 taccggtacc ggtattgttg ccggagatga ggaacattct gtttaaaggt atttcgggga
     1621 tttccgcttt ggcacgctct ttgcccatca tttcgtaggc gacttttgcc tttttgtaga
     1681 cattcatctc tttttcaact tgttggcgga tatcatcgtg gataggcata acgagcaggc
     1741 ggatgagtga tagtactccc ttgcccgagg ctgccggagc tacaatgaag gattgcatgc
     1801 agggcgattg gtatttgccg gcataatgac atctcacgta tcgttccatg gtggcaccca
     1861 gggcagtcaa tgctccgagc aagagtacgt ctttttgagt ggcggtagtg ccataactta
     1921 tgatacgtag cagtagcttc ggccagtctt ctaaggtgaa agtaggtaat gggtgatgcg
     1981 ggtcgctgcc ttccagcagt tcttctgatt cactcttttc ttcttctact ttattatata
     2041 cgtgcgcgtg tgtggaaaaa ttgtgcggtg aactttctgt acctactgta cccgtccggt
     2101 tgttcataac ttccttccgg tcttccctgc agatttttac tcctgtcgat tcagcgaggt
     2161 gaaatgccgt tccgagatgt attgctccct gctgtttcgt gagtgcattg gaaaacattc
     2221 gttcggcatg ggcggattga tacttggcgg aaatccggca caggcgatga aaaaactccc
     2281 gtcctgcttc accacagtcc gttgcgatgg cgaatgctaa ttgtacgtac tcggcgtaag
     2341 tgggtgcaat gtcggcacct gctgtttcga ctgcttcggt gaggaggcgt aaagattcaa
     2401 tatcggtcat tttttgataa ttgacaattg acaaatgata attgacaatt gaagtttgat
     2461 cattcgtgat tataatttaa tattctctga atagtgcttg tgggtcatgg ctgaggaagc
     2521 aggctcttac gatgtctttg ccggaggtgt ctacggcttt ttgaactgtt tcgatggagt
     2581 tgttcatttc tgatccgtag gtcatttcta cgtattccat tgcccagctc atactctctc
     2641 ttacattacg gctctgatcg tctgtgtaca ggttgctgta aggtacgaat gttttcacac
     2701 cccggttgct gggactgata aatgcgagta cagggtggag aaaaggatcg tcgaacagtg
     2761 tacgacgcat ttctacggct ttctgatagg agtcgaggtt atctatatct accactacga
     2821 gtccggaagg agatgcgaag aatttactgt tccggcggat gaatgtgccg cacggagtca
     2881 cgtatggcag caaggatgtt ttcgccattc gtatatcttc ggcgctgcgc acctgttcgg
     2941 tcagtgcttt gagattttca ttgcaggtga tcatctgata tacttgctct actgagactt
     3001 cgcagaaggg agtgagagtg gcgggtgtaa cggtttgtcc ttgttcgttc ctgatgggag
     3061 caatcggggg catgaaataa gacattctga aaaagttttg catagaatac ttctattagg
     3121 acgtttaata aatgactttg actttcaaag catggtgcga aagtaagaca aataaaataa
     3181 gtcgagttca gatatgtctg aagtagtgtg aaaatgttta atatataaga cgtgttttta
     3241 actaataata agaaaaatgg aaaataaaat cgtgcatcct aaactcggtg agtttattga
     3301 aaaggtgctt aaagtagcac atgtgaatct ttcaaaaatg tgtcaagaga tacatatggg
     3361 acctgctact taccaaaagg taaaaaaggg gaagaaaaag ctctgattca ttatgagcgt
     3421 attcttgaat attattatag gactcgcacc gaagaagagt ttttggagaa agtgaatgag
     3481 tgggcaaaac tttatattcg atataagaag gagaagaatg acatttgaat attggaattt
     3541 tttagtagct ttgtgaaaaa gaaagttgtt atggaagatt tgcagagatt atatcctata
     3601 gggatacaga cattttctaa gattcgtgag ggaaatttcc tctatgtaga taagacagaa
     3661 tacgtttacc ggatgacgca ttctgcttcc agttatatgt tcctgagccg tccgcgtcgt
     3721 tttggtaaat cattgttaac ctctacgttg catagctatt tctccggtcg tgaagaactg
     3781 tttcgtggat tggcgatgga gaagctggag aaagaatgga tacagtatcc ggttctgcac
     3841 ttcgatatga gtatggccaa gcacgtggac aaagataaac tgatgaatct tttagacttc
     3901 atgctaacag aacacgaacg tacactaggg attgatgcag caggtacaga ccctaatttg
     3961 cgcctgacta atctgataaa acgtgcttat gaacagactg gcaggaaggt cgtggtcctt
     4021 attgatgaat atgacgctcc tttgctggat gtggtacacg aacgggagaa cttgggggta
     4081 ttgcgtgacg ttatgcgtaa cttctatagt ccgttgaaag cctgtgatcc ttatttgcgc
     4141 tatgtgtttc ttacaggtat cactaaattc tcacagctca gcattttcag tgaactcaat
     4201 aacatcaaaa atatcagcat ggatgaacct tatgctgcca tttgtggcat aacggagaat
     4261 gagatactta cccaaatgaa agaagatgtg gataggatgg ctgtcaaatt gaatattact
     4321 gcggaggaag tactggctaa gttgaaagag aattatgacg gctatcattt cacttatcca
     4381 tcgcccgaca tctataatcc attcagtctg ctcaatgctt ttgcagatgg gaaatttaat
     4441 tcttattggt ttggtagcgg cactcctacc tatctgataa agatgctgga taagtttgga
     4501 gtagagcctt ctgaaatagg aaataaattg gcggcggtcg aagaatttga tgctcccact
     4561 gaaacgatga gtagcattac tccattgctg tatcaaagcg gctatgtcac tatcaaggat
     4621 tacgataagg aattggaact atatacgttg gatattccta ataaagaggt gagggtggga
     4681 ttgatgcgaa gcttgttgcc ttattatgta accaatgaca cacgtgaggc gacgaacatg
     4741 gtggctttta tttcccgtga tatccggaaa ggtgatatgg acgcggcatt acggcgtttg
     4801 caaacctttc tgtctactat acctcaatgc gatcatacaa agtacgaagg tcattaccag
     4861 caggtattct atatcatatt cagcttgctg ggatactatg tggatgtcga agtacgtact
     4921 tcccgtggtc gtgtggatgt agtgttgcgt actgaggcca cattatatgt gatggaattg
     4981 aaactggata agaatgcgac agttgctatg gaacagataa atttaaagaa ttatccggaa
     5041 cgctttgctc tatgtggact gccagtggtg aaggtggctg ttaattttga tagtgaaagt
     5101 ggcacactgg gggattggat gattgaaaaa tagagattga taagtgaata taaaaagtgt
     5161 aaggacgaag gccattttct ttaattatca gattaataac attttaataa ctccctaaaa
     5221 taaaaagagc cccgcaaggg gcttttcctt tgtcttttta atagacatgc aaagaataat
     5281 gtgttttttc ttattgtaac cttacgattt atactttttt attcctctct taattaattt
     5341 tatcacaaat atttggtatt ttcggacgct ttttggacaa acgacttgaa ttactaatag
     5401 tttattatat ggaaaatatc gaaacagcga tcctgctgat ggtggtcggc atggctaccg
     5461 tatttgttat tctgctgatt gtgatttatt taggtaagtt actgattact cttgtcaaca
     5521 agtatgctcc cgaagaagtg attcctgcga agaaggaagc gctacaaggt cctgcgccta
     5581 ttccgggtaa tataatggcg gctatcacag cagctgtgaa tgtggtgaca ttaggaaaag
     5641 gaaagattac aaaagtagaa aagttataaa cctatcaaaa gtatatcata gaaaaacatg
     5701 aaaagagaag ttaagtttag tctggttttc cgagatatgt ggcaatctgc cggaaaatat
     5761 gtacctcgtg tagaccaact cgtaaaggta gctcctgcca tcattgaaat gggctgtttc
     5821 gcccgtgtag aaacaaatgg cggaggtttt gaacaagtga atttattgtt tggtgaaaac
     5881 ccgaatagag ccgtgcgcga atggacgaag ccgttccacg aagccggcat acagacacac
     5941 atgctcgacc gtgcattgaa cggactccgt atgagccccg ttccggcaga cgtccgcaag
     6001 ttgttctaca aagtaaagaa agcacaaggc acagatatca cccgtacatt ctgcggattg
     6061 aacgacgtac gcaatatcgc tccttccatc acgtatgcca aagaggcagg catgatctca
     6121 cagtgttcac tctgtatcac ccattcgccg atccacacgg tagagtacta caccaatatg
     6181 gcgttagaac ttatcaagct gggggcggac gagatttgca tcaaagacat ggcaggtatc
     6241 ggtcgccccg tttcattggg caagatcgtg gccaatatca aagcggcaca tcctgaaatt
     6301 cctattcagt atcatagtca tgccggtccc ggtttcaaca tggcaagcat cctcgaagta
     6361 tgcgaagccg gttgcgacta cattgacgta ggtatggaac cgctttcatg gggtacggga
     6421 cacgccgatc ttctcagcgt acaggctatg ctgaaagatg ccggatatca ggtaccggaa
     6481 atcaatatgg aagcctacat gaaagtgcgt gcgctgattc aggaatttat ggatgacttc
     6541 ctcggcttgt atatcagccc gaagaaccgt ctgatgaact cgctgctgat cggtccggga
     6601 cttcctggcg gtatgatggg tagtctgatg gctgacctcg aatcgaatct ggaatctatc
     6661 aacaagtata aagccaaaca taacctgccg tttatgacac aggatcagct gctgatcaag
     6721 ctattcaacg aagtggcgta tgtatggccc cgcgtcggtt atcctccatt ggtaactccg
     6781 ttcagccagt acgtgaagaa ccttgccatg atgaatgtga tggcaatgga gaaaggcaag
     6841 gaacgctggg gaatgattgc cgacgatatc tgggatatgc tgctaggtaa agcaggacgc
     6901 ctgccgggta cactggctcc cgaaatcatc gagaaagccg aacgtgaagg acgtaaattc
     6961 ttcgaaggta atccgcagga caattacccc gactcactcg acaagtatcg caagctgatg
     7021 aaggaaaaca aatgggaagt gggagaggac gacgaagaac tcttcgaata tgccatgcat
     7081 ccggctcagt atgaggctta caagagtgga aaagcgaagg aagacttcct ggcagacgtg
     7141 gcaaaacgtc gtgcagagaa agataaatcg ccggaagaag atgcaaaacc aaaaacactg
     7201 actgtacagg tggacggaca ggcttatcgt gtgacggtag catacggaga tgccgaactg
     7261 cttgctgcac ctgtagctgc agctccggca ggagagggca aagatgttct ttctccgctg
     7321 gaaggtaaat tcttcctggt gaagaatgcg caggaatctg ccttgaaagt tggcgatgcg
     7381 gtgaaagagg gcgatgtgct ttgttatgtg gaagcaatga agacttacaa cgctatccgt
     7441 gccgaattta gcggtacgat aactgctatc tgcgctaatc cgggagacac tgtttcagaa
     7501 gatgatgtat taatgaagat aggataatga acgagatatt tgagaactta tatgacatga
     7561 ctgcgttcag caatatcatt gccgaaccgc agtttctgat aatgtatgcc atcgcgttcg
     7621 tcctgcttta tctgggtatc aagaaacagt acgaaccgtt gctgcttgtt ccgattgctt
     7681 tcggtgtgtt gcttgccaac ttccccggag gagatatggg agtgatacag gcagacgaga
     7741 atggtatggt gatgataaac ggtgtgatga agaatatctg ggaaatgcct ttgcatgaca
     7801 ttgcgcatga actgggaatt atgaacttca tctattatat gctgatcaag accggtttcc
     7861 tgcctccgat catctttatg ggggtcggtg cgttgacgga cttcggaccg atgttgcgta
     7921 atctgcatct ttccatcttt ggagctgctg cacagttagg tatctttact gttctgttgg
     7981 tagccatcct gatgggattc actccgcaag aagctgcttc actgggtatt atcggtggtg
     8041 cggacggacc gacagccatc tttacaacga tcaagctggc tccgcatttg ctgggtccga
     8101 tcgctattgc cgcttattct tatatggcac tggtgcctgt gatcattccg ttggtagtga
     8161 agctgttctg tactaagaaa gaactgagca tcaacatgaa ggaacaggaa aagaaatatc
     8221 cttcgaagac ggaaatcaag aatctgcgtg tactgaagat tattttcccg attgtagtga
     8281 ctacgattgt agctctcttc gtcccaagtg cagtaccttt gatcggtatg ctgatgttcg
     8341 gtaatctggt gaaagaaatc ggaagcaata ctttccgtct gttcgacgct gcttccaaca
     8401 gtatcatgaa tgctgctact atcttcctcg gactttcggt aggtgcaacc atgacggctg
     8461 aagccttctt gaactggacg acaatcggta ttgtcatcgg tggtttcctt gcatttgctc
     8521 tttctattac cggtggtatc ttctttgtga agttagtgaa tctattctcc aagaagaaga
     8581 ttaatccgct gatcggagcg accggactga gcgctgttcc gatggcaagc cgtgtggcga
     8641 atgagattgc gttgaaatac gatccgaaga atcatgtatt gcagtattgt atggcaagta
     8701 acatctcagg ggtaatcggc tcggcagtag ctgcgggtgt actgatctcc ttccttgcat
     8761 aataaaaaga acaaccaata aaaattaggc acggattacg cggataaaca cggtttttag
     8821 ttactcaact cttaaaaccg tgaaatccgt gtcatccgtg cctaattttg tttttatcta
     8881 ttcgctggtc accttcttgt attcagccac agccatcttc tctgccagat aagcattgat
     8941 cagattggtg tgtgcttgcg tccatgacaa ctgggcggaa agtacatcta ccatgctcgc
     9001 ttttccttca ttgtaggaga aagtggccag atccagattc tcatttgcca gactcatgtt
     9061 ttctttcgct gttttcacct gagattctgt ttccgtcagt ttggtgagag ctgccgacag
     9121 ttcttcgttg atattgtccg tcatataact ctgttgcaac ttttgtattc cgatatatgc
     9181 cttctgctgt cggttcgtct tgaaacgggc tccccagcgg aaaatgggaa tattcagatt
     9241 gactcctacg atgggattaa aagatacgtc gtatcccaag ttgggtgtgg ccgttgccca
     9301 gccaccgctg aaatacatgt ttaattgggg attgaactgg ctgagagccg ctttacgttg
     9361 tgcctggctc ttcatgatgt ttacttccgt actggcataa tcggcacgtc gttgcaaaac
     9421 atcttccaga ggcagtatcc ggacaggagc ggagatcatt ccgatgttgt acaggctgtc
     9481 tacaggagta ttcggtgctt ctcccatcag aatattcagc tgttgcagcg ctaatgtata
     9541 attctggcgg gctttgatat actgcagttc cgcttctttc agccgggtgg aaatcatcag
     9601 aagatctgta cggctgatca ttccgtcatc gaaacggtcc tgaataatgt catattgctg
     9661 tttgacaatg ctctggtatt tgtcggctgc ttgtagcatg gcttttgaag cggaggcatt
     9721 ccagtagaca gcatcacttt gatagtgaat ctggtctaac gtgagttcct cgttcagctg
     9781 gttcagcttt tcgtctgcct tcgctatctg atgttgggca ttgagcgcac cgcctgtgta
     9841 gagtggctgt gatacgacaa atactccctg gtaggtatgg ttgcggtatt cgcccaccgg
     9901 ttcgttccat gcgctaaggt cgctcatgtt cagggtaccg tctgcattta cgtcgatttt
     9961 cggcaggaaa cctgtatggg ctatctttcg cgcctccgaa ctggccaatg tctttagttt
    10021 ttgttgtttc aatatctggc tgtaagcctc cactttttcg cggtaggcgt cctgactcag
    10081 gcagggctgt tgcgcccagg ctgtggagcc aaggagcaac agtgaaaata gtatgagttg
    10141 ggttttcatt tctttcatgg ataatctttt aatggataat ggatagttga taatggataa
    10201 ttattgttct cctttgatcc ggtggatggc gcaataggct acaggaagga cgaatagtgt
    10261 caatgccgag gctactaaca gtccgcccat gatggtggcg gccattccgc cgaacatggc
    10321 gtcgaacagt agcggtaaca tacccagaat cgttgttccg gaggccatcg ctaccggaat
    10381 gatgcgactg gtcgtggcac tgatgactgc gtccagcggt tttttgcctg ctgctgtttc
    10441 caaatcgatt tggtctacca gtacgatagc gttcttgatg ttcataccaa tcagacctag
    10501 cagacccaat atggagaaga agtcgaacga cttgccgagt acgagcagtc ccagcacgat
    10561 accgatgaag atcagcggca gcattaacag gatgacggtc ggcttgcgat acgtcttgaa
    10621 caagaagagc agcgtcacaa acatcaggaa gaatgtcagc ggtaagtttt tggccagcgc
    10681 ttcattcgat tccacctgac tttcctgttc gccgaaatac ttcatggtat atccttccgg
    10741 tatttttatc tcttgctgta cttgcgacca tacctggttg aaagcggaaa tcgcattggt
    10801 tccgcgacgc gggtcgcatt gtgccatcat caccatctgc cggttatagt ctttcacgtt
    10861 cgagaaccgg tactggaagt caaattcaga tactacctgt tccaggctgg tcgtctcgtt
    10921 gcctgtcccg aatacgggca gtgtgcgcag atcattgatc cggaatgaat ccagctggtt
    10981 atttttcaat aggataggaa gtacctgatc tccctgccgg tattctccca aagtcattcc
    11041 tgtggtaccg atctgaatgc tctgtgccat tccctgtcgg gatacaccca gcggttgtgc
    11101 ccgttccggg ctgtaaaccg gtttccagac gggtatcttg tttccccacg aattgcggat
    11161 attaattaaa tccggattct ggtgcataat ggctattgcc tgattggtaa gtgatacaag
    11221 cgtatccaca ttcggaccga taaagccgat ttcgatagcc gcatccactg cgggggacag
    11281 tttgaacaag ctggtccgtg tgattgcact cggataattg gctttcatat atccgtcaaa
    11341 atcttcttcg tattctttcg tatatttact gtctgtcagt tcgacgagta cattggcaaa
    11401 attcggtttc ggacctacgg aagtggaggc aaggtaatac cttagcgggg tgctgccgaa
    11461 tgtgatggat acctttttta cttctggctg cttcgccagg tgctcttcta ccgatttcat
    11521 ctctttcact acgtcattga tgctgtatcc gtccggatag aatacatccg cccggaaata
    11581 aggcttatcg agcgacggga agaagttctg cggcatcgtt cccataataa tgagcgagat
    11641 gatgaagagg atcaccatgg ataccagtgt cactgctttc ttgcggatca atactccgag
    11701 aacgaaagcg aacttatgat agaacggctt gtcgtatgga tctttcgtgc tgtcgcctgt
    11761 tttggctttc agaatgaaat ttccgaatac ggtagtctgc gtcagggcaa gtacccagct
    11821 cagtcctagt gaaatggcaa gtaccacaaa cagcggtttt acgatttccg ctacagcaga
    11881 gggagcaagg taaagcggca ggaaggagca gatggcaatg aaagttgctc cgagcaagcc
    11941 ccattgtggt ccggttgctc cgtctatcag ggctttccgt cggtttacac ctcgggcaat
    12001 ggctatttgg gcgttgtccg tcactacgat ggcgttgtcc accagcatac ccatggcgat
    12061 gataaatcct gccaaggacg ttctgttgag tccgacgccg aagaaagaca tgatgagcag
    12121 tgtacctccg atagagaaaa tcagcgaaga gccgatgagc agaccggcac ggagtcccat
    12181 caccagcatg ataatgacaa tcacgatcag gatggattcg atcaggttga tgataaatcc
    12241 gttgttggct tcgttggcga tctcgttttc gaggtagagg ctttgcagtt ccagtcccac
    12301 aggcatgagg gggaggagct cgttcagttt tacttttacg ttctcacccg tctgcactac
    12361 atctctttgc gggtcggtgg aaacaccgat gccgatagcc cgtttcccgt tcacatgcat
    12421 gatgttggat ggagggtcga gataaccttt ctcgatcacg gctatgtcgc ccagtttcac
    12481 ctgtccggct ttggtggtga ttacctggtt gcggatatcg tctatgttgg catacattcc
    12541 gttggctgtc acccgtaact gctgtacgcc tgcacggatt tctccggtgt tgataatctg
    12601 gttctgcgat tgcagcaggt tggccagctg tttgggatcg atccccattc ccaccagttt
    12661 gttggtagaa acgaagatgt tgactacttc cgtctgtacg ccgaacagcg ctactttcat
    12721 cacgccgtct gctgtgacaa cctgcgtctt gatccgttcc gcccagttgc gcatttcctc
    12781 ataggtgaag ccgtcatctg ccgtcagtcc ataataaatg ccgaatacgt cgccgaaatc
    12841 atcggagacg gtcggggtgg aagcaccgct gggcagctgc ggctgaatat tgagcacttt
    12901 gcgtcgcagc tcgtcccatt tctgagggat ggaactggcg gaaagtgagg gttgcagttc
    12961 gaacgtgatt ttggagagcc cgtacatgga ctctgatttt atcttgtaca cgccgctcat
    13021 actttgtatc tcacgggaga taggctctgt gatcagccgt tctacttctg ccggttcggc
    13081 tcccggatag cgtgtcatga tgaccgctga tttgataacg aagggggcat cttctttctt
    13141 gcccagcttt ccgaaggagg taatacctcc aatcagcagt acggcaagga agaaatagat
    13201 gatcttcgtg ttatccagtg aatattttgc taaattcatt tgtctattga tttaatactt
    13261 tctccttcta ccaactggta tactcctgct atgacgattt gttctccggg tttcagtcct
    13321 tcggacacga gtacttgcgc ctctcctgtg ggggcattga cgacgatttt gcgtttgtgc
    13381 actttgttgt cctctactac ccagacatac atgttgtttc cgtcactttc gccgaaaaca
    13441 gcactgagcg ggatgattgt ccagctatcc tgcaccaatg ggcctacatc ggctgtgaaa
    13501 cggatgctgc aagtgaagcc gggcttcacg gcatataagt cccggtcgaa tgaagggtcg
    13561 tcgatagtga tgctgaccgg aatacccgtt ccttcggtgg atatgtccag atattcctcc
    13621 agtcttgcct tgaatacatg gcccttgaag gtatcaaact ctacaaggaa acggggatct
    13681 ttggcacgga ggagataaag atatgcatcc ggtatggtga acttgatacg caggttctgt
    13741 gtgttgacca gttgtacgat cccttctcct gaattgacac gctggtagtt ctccaccagc
    13801 cgcttctcga tagaaccgtc gaaaggggcc gtcagtttgg tgtcacgcat gttgttgctg
    13861 gacagttcgt actccgattt tgctttctga taattggaaa ggctgatttc atactcctgc
    13921 acggagatcg cttgccggga gagcaggcgc ttgttgcgtt ccacttgtgc ggaagccgtt
    13981 tcgtaggcag acttggtggc agcatactgc aatgcgatat ctctgggatc gatagctgca
    14041 atcagttgcc cttttttcac tttctctcct tcgataacag gcaggctgat gatctgtccg
    14101 ctgacgcgga atgccagttt gacatactcc actgcttcta caatgccgga gaagtctttt
    14161 ctgattactg accttgattc gacaatagtt gtcttaacag gtcgggtggc gggtgccgtc
    14221 atctcttttt tttgcccgca gccttgaaat aggatggctg cgagtgcaat cacatagata
    14281 tttttcataa gtcgttcatt gtttgggaag taaacaattt gatacttgac tatgttcagt
    14341 agagacgggt atattagaaa tgtgaaatta gtatcaacat taaaggaaaa tgattgttta
    14401 tagataaaaa atgccttttc tgttgatttt atcagagatt attcccactt ttgcaccgca
    14461 ctagtattac agtcgcggaa tgcgatatga gaatttaatt ctcgaattta agctacgagc
    14521 atgtgggaat atgctcgtgg cttccttaga tatacggttc tgtcccccgt gtggagcgtt
    14581 aatgcgccca ctgtatctca tccctcgtgg actgtaatat gtagtgcaac gggtcagcag
    14641 gaccgtcttt tttgcctgct gaatattatt atatataata ggaagtattt ctcctgaata
    14701 gtactattta ataaaccatc atttttcagg agatcagaca atataatggt atggtatatt
    14761 cccttaacta taccattttt atattacctg gtaatagttc cccttagcca gttaatatac
    14821 ggaccgcact actctgtgaa gaatggtgcg gtcctttagt ttatctatga aacgaaaaag
    14881 aggaaatttc caaccggaaa tctcctcttt tttcatctta acgaaagatt gaattatttc
    14941 ttcttacggt caccgtaacg gctcatgaac ttatcaacgc gacctgcagt atctaccaat
    15001 gtagatttac ctgtatagaa cgggtgagaa gtgttagaga tttcaatctt cagcaacgga
    15061 taagtttcac cttcgaattc gatggtttct ttagttgcta cagttgattt agacaaaaac
    15121 atatcaccat ttgacatatc tttgaatact accggacggt atgattctgg atgaaggcct
    15181 tttttcattt cagtatctgt ttttttaatt tatattctgt tactattttg gtaagaaata
    15241 gtgtaatggt cattttcaga gcgcaaagat agcacatttc tccggaatag aaaaaacttt
    15301 gctgaaaaaa cttctgtgaa ttatgctatt tctatgaatt atatgattgg cacgaaaaga
    15361 atgtcttgtg ctttttatgg tataatacct gttttgggat agaacctttc agccgtttat
    15421 ttgctaggtg gacattacaa tctaatgtca gacccgctta cggatgaata tttgctgatc
    15481 gatttaaacc tttttctatt atatttttct ttccgatgct cgttattcgg tggataatgc
    15541 ttacttttgc gtagaatttt aattcactaa caataaactt taaacaaaat ggttaattac
    15601 aaagacttag gattggtaaa cacaagagac atgtttgcta aggctattaa gggtggatac
    15661 gctatcccag cattcaactt caacaatatg gaacagatgc aggctatcat caaggctgca
    15721 gtagaaacaa aatctccggt gattcttcag gtttctaaag gtgctcgtca gtatgctaac
    15781 gctactttgt tgcgttacat ggctcagggt gctgtagagt acgcaaaaga attaggttgc
    15841 gcacatcctg aaatcgttct tcaccttgac cacggagata cttttgaaac ttgcaaatct
    15901 tgcatcgatt caggtttctc ttcagttatg atcgacggtt ctcatcttcc ttacgaagaa
    15961 aatgttgctt tgactaagaa ggtggttgaa tacgctcatc agttcgacgt aacagttgaa
    16021 ggtgaacttg gtgtattggc aggtgtagaa gatgaagttt cttctgacca ccacacatac
    16081 actgaccctg aagaagtaat cgatttcgct actcgtacag gttgtgactc attggctatc
    16141 tctatcggta cttctcacgg tgcttataag tttactccgg aacagtgcca catcgatccg
    16201 gctaccggtc gtatggttcc tcctccattg gctttcgaag tattggatgc tgtaatggaa
    16261 aaacttccgg gattccctat cgtacttcac ggatcatctt cagttcctga agaagaagtt
    16321 gaaacaatca acaagtttgg tggtgctctg aaagctgcta tcggtattcc tgaagaagaa
    16381 ttgcgtaaag ctgccaagtc tgctgtttgc aaaatcaaca tcgactcaga ctctcgtctg
    16441 gctatgactg ctgctatccg taagactttc gctgaaaaac cagctgaatt cgacccacgt
    16501 aagtatcttg gtccggctcg tgacaacatg gaaaaactgt acaagcacaa aatccttaac
    16561 gtgctgggtt cagacaacaa attggctgaa taatcacaga ttatcctatt atatagaaag
    16621 gctgcaatcg tttgacggtt gcagcctttt ttacgtaata tcctttatct gcttattccg
    16681 gtttctgagc gggcacattt cctcccaaga agaaatcttc tatcttttgc ttactttgaa
    16741 tgtctttcag ccagttggct gcagcattat aataattctt agtgcctaaa acgagttcgc
    16801 ctcgttcgtt tagtttcgct tcttcttcct tatcttcttt cgggcgtgtt tttaagaatg
    16861 cttccagaca gcgttcggta tttttcttgt ctttcagcga atagaaataa atgaaagcca
    16921 tatcatagag cagtttatga ttttgtttat cgtatttccg gtagcgttct ctgatcgatt
    16981 caatctgctc tttaggcatc tgtgccattt tgtagcagtc ggtcatgcca atatagagcc
    17041 gtaccatatt actgtctttg ggaatagtca gatcaagcgc tttttcgaga tactctacgc
    17101 ctaacttctt ccatgaagtc ttggcgcagg cacggccgag ataataaagc aggtttacgt
    17161 tttcaggatc atgttttcgg gcggcttcca gaaagtcatg tgcttcgtaa tatttctctt
    17221 ctgcataata gctgataccc agataataac aggtatgaaa agaactgtcg ccctggctca
    17281 ccaggtattc ataacgctgg atagcggtag gataatcctt attcagacaa tatgccagtg
    17341 cattctgacg gttgacagcg atattggtgg tatcaatctg ccgatatttc tccgtggctt
    17401 caattgcttc gttgaaataa gaaccggcta tgttcagtgc ggcgagcttg gcggcggcaa
    17461 gatagtcgtc ggggtatttc tcttgtatat tatagtagca ccccgtggcg gggagaagct
    17521 ctcccatacc ttcgaaactt tgggcctgca gatgcaaggc gatggcggaa ctgtctttct
    17581 ctgtcatcag actactttct cctaaagcat cctgaaactt ctgtaaagag agcagtagtc
    17641 cgatgtattg aatacgcaca tatttgtttt ccggattcag atcaagtgcc tgttcataat
    17701 atttcagtgc ctgttggtat ttggccaatg aacggcagca ttcggctgct tcgatatatg
    17761 cacgggtatt ggcagtgtca ttggttatga tttcctgata agtggaaagt gcttctgtat
    17821 tcatcccaag tccccgttgt gctttacctt tttgcaagag taggggaatt gtcggctttt
    17881 ctttggcaat gagagtgaga gctgcctcgt aatcgtagtt tgctattgct tcctgaacat
    17941 gattgatgcg ctgcgccatc accagggtgg tggtacaaag gaaggcgagg agaataatcc
    18001 gtttcataaa tatttatttt agtgtgtcgt aacaaagacg caagatgcta aaaaatatcg
    18061 tatttacgaa ttattcgtag cctttttgga atagattaac ggaatgataa gagaagataa
    18121 cataatgata agtgcggata ttgcatctaa aacagcaata tccgcaccta atattttgtc
    18181 ccggcattcc gaatggaaac ctgacagggg caccttgtcc ctacattaag aatcctaaca
    18241 ggataccggc agcaacagcc gaaccgatta cacctgctac gttcggaccc atagcgtgca
    18301 tcagcaagta gttggtagga tcatattcca gaccgacaac ttgtgagata cgtgcagagt
    18361 cgggaacggc agatacacct gcattaccga tcaacggatt gatcttattg cccttcttga
    18421 ggaagaggtt gaagatctta acgaagatca cacctgatgc ggtagcaatg ataaatgaca
    18481 gagcaccgag ggcgaagatc ttgatggagt cgagtgtcag gaactcagaa gcctgagtag
    18541 aagcacctac ggtcaaacct aacaggatag tgattgtgtc aatcagcgga ccgctggctg
    18601 tgttagccag acgacgggtt acaccacttt ctttcaacag gttaccgaag aacagcatac
    18661 ccaacagagg cagaccggaa ggaaccagga agcaggtcag caacagaccg ataatcggga
    18721 aaatcacttt ctctgtatga gaaacggcac gtggcggttt catacggata acgcgttcgt
    18781 gtttggtggt gagcagacgc atgataggcg gctgtatcac cggaactaac gccatatagg
    18841 agtaggcgga taccgcaatg gctcccatta agttaggtgc cagcttggac gaaaggaaga
    18901 tagccgtcgg accatctgct ccaccgatga taccgatagc accggcctgc atcgggtcaa
    18961 atcccatttc caatgcgatc atgtatgcac cgaagatacc aaactgggca gccgcaccga
    19021 tcagcatcag cttcggattg gagattagcg ccgagaagtc tgtcatggca ccgataccta
    19081 agaagatgag cggtggatac cagccggacg ttactccctg atacaatatg ttcaatacag
    19141 aaccttcttc atatataccg acttttagtc cggcgtccat attgaaaggt atattaccga
    19201 tcagaatacc gaatccgata ggaattaaca acatcggctc gaactctttg gctacagcta
    19261 agtaaataaa gcctaaaccg ataatgatca tagcaatatg tccacctgtc gcgttggcaa
    19321 atcccgtgta ggtccagaaa tcggcaaggt tatttcctaa aaagttaata aaatctccca
    19381 tattattcaa taattacgag gtcattacct tcaagaacag aatctccctt gttgacattg
    19441 atggcagtca ctttaccgtc tttgtctgca ttgatattgt tttccatctt catggcttcc
    19501 aatataatga tagtctgtcc tcttttcact gtatcaccta catttacttt gatgtcaagg
    19561 ataacgcctg gcagtgggga cttaacgcct gatttgccgg tagaaggagc agccggtttt
    19621 actaccggtg tggtaggagc agccggtgag ttaggcatag ggcgtactac tgccggtttg
    19681 ggagtagctt tcggttgttt ctccatttct actttgtaat gcgtaccgtt cacttctaca
    19741 tgagcgatat tatcttcaat atctccgatg gttactttgt atgagttacc gttgatttta
    19801 tatttatatt ctttcatcgt tttatctttt tagggaatga tttactttct gttaggattt
    19861 tcacgcaagg tgtaaatctt cgaactccac ggtgaataac tgcgcttcac acgagtgatg
    19921 gtcagcaccg tttcttctac gtcgtgtacc tcatcctgca tttcgtgtaa tgccattgaa
    19981 atagcagcat aaacttcacc cggagcctgt gaaagctctt tcgcttcgac tttatcgatg
    20041 cctttagcct tcatcgcatt gcgtttgctc aggttgacag caactttacc taccaccttg
    20101 aaggcaatga agagaagaat caatccgcag aatactacgc tcatggctga aatagacata
    20161 ccgataccga ctgagtcatg ttcttcgaac ttttccatct tggcattact gtcaagggtt
    20221 ttgttgttcg tgctcggggt tacgtatttg tctttgcttc cgccttttac ttcccagtct
    20281 gctgctccgt cgcttatgcg tgcataagac tggttgggac ctaaagttcc tgctggtatg
    20341 acaacttgat caagtagctt tctgcctgaa tcaaaaagac cgacccaatt ggctgtttcg
    20401 ggattcagtt tgaagctggt atggaaggtt ccacgattag gttcgccatc tgcccaaaat
    20461 aacgcatgtt ggcgtggctt tactaatgta agtatgtcac cttttgggat aaaataggtt
    20521 actgtatcgc ccggctggct gcttactttc aataaacaag ctgctaagtc tgcgctaccg
    20581 tatgatttgt tgaatatttc aatccatgca ctgtgcaagc cgtagtcatc ctgaaagttg
    20641 ttttgattgt ctatcaggac ttcattcagc aatagcttat tgttcgactt ttgctctccg
    20701 caggaagtca atccaatcag caacagcaga gaaaggaata ttccgatttt ggttttgttc
    20761 ataatcgttc ttgttttaat gtgaaaagtt ggattacaac ggaatattac catgtttctt
    20821 cgccggatta gacagtttct tagtctgcaa ctgctgcaaa gcacggatca cgcggaaacg
    20881 tgtgttacgg ggttcgatga catcatcgat gtaaccatac ttagctgcat tataagggtt
    20941 ggcaaacagt tttgtatatt ctgcttcttt ttcggcaagg aactgagccg gattttcctg
    21001 gtctttggct tcacgcgcgt acaatacttc tactgcacct gcaccaccca ttacagcgat
    21061 ttcagctgtt ggccaagcat agttcatgtc accacgaagt tgtttacaac tcatcacgat
    21121 gtgagaacca ccgtaagatt tacgcaatgt gattgttact ttaggtacag tagcttcacc
    21181 gtaagcatac agcagtttgg caccatgaag gataacgcca ttgtattcct ggcctgttcc
    21241 cggaaggaat cccggtacgt ctaccaacga cacgataggg atattgaaag catcgcagaa
    21301 acgaacgaaa cgtgcgcctt tgcgagatgc gttgctgtcg agtacaccgg caaggaattt
    21361 aggctgattg gctacaatac ctacagactg accgttgaaa cgggcaaaac cgataatgat
    21421 attcttggca tagtctttct ggatttccag gaattcgccg ttgtctacga tagcgctgat
    21481 aacctcgtac atatcatacg gtttgttggg gctgtcgggg ataatatcgt tcagtgaatc
    21541 ttccagacgg tcgatcggat ctgtgcaatc cacgtatgga gcttcttcga ggttgttttg
    21601 aggaatatag ctcagaagtg tgcggatcaa tgccagacct tcttcttctg ttttggcagt
    21661 gaaatgagta acacccgatt tggtagagtg aacgcttgct ccgccgaggt tttcctggct
    21721 tacgtcttca ccggttacag ttttcacaac tttcggacct gtaaggaaca tataagaagt
    21781 accttccatc atcagtgtga agtctgtcag tgccggagaa taaacagcac cgccggcaca
    21841 aggaccgaag ataccggaaa tctgcggaat gacacccgaa gcgaggatat tgcgctggaa
    21901 gatttctgcg taacctgcca aagcgttaat accttcctgg atacgtgcac cgcccgagtc
    21961 attgataccg atacaaggag cacccatctt cattgcctga tccataatct tacagatctt
    22021 cagtgacatt gtttccgaca gtgaacctgc agtaacggta aagtcctgtg caaaaagata
    22081 tacgagacga ccttcgatag taccgcaacc ggttactaca ccatcacccg gatagtgctt
    22141 tttctccatg ccgaagttcg tgcatctgtg ctcaacgaac atgtccattt cttcgaagct
    22201 accttcatcc aacagcatgg ctatacgctc acgcgctgtg tatttccctt tttcatgttg
    22261 cttcgcaatt gctttttcgc cgcctccgat gcgtgcaacg gcacggcgtt caataagctc
    22321 tttaattttt tcaagttgat tactcatgag ttcttgttgt ttttttagag tttatgatta
    22381 gtgttcgcag agttctgtca gcacacccag tgttgatttc gggtgaagga aagcgatgtt
    22441 cagaccttcg gcacctttgc ggggagcctt gtcaatcaga cggatttctt tgctttctgc
    22501 ttctgccaaa gcattagcta cgccatcttc tacggcaaat gctacgtgat gaacacctgc
    22561 acctttgttt tcaataaatt tagcaatggt gctttcgggg caagtcggct ccaacaattc
    22621 gatttttgtt tcacctacct ttaaaaaagc ggttcttact ttttgatctt ctactgtttc
    22681 gatgttgtaa catttcagac ccaatacgtt ttcgtagtaa ggaagggctt cttcgatgct
    22741 ttttacagca atgcccagat gctcaatgtg tgaaatcttc ataactatat ttttttatat
    22801 ggtttaatta tgtgcttata tggcataaaa cagcacaaag aaagacattt cttgtctaat
    22861 aaagaaatat ttctgcattt aattattggg gaataaagca taaaaaatgc tccggatggg
    22921 tgacaaagac gggttttgta atcttgagat tacatttaga cataaaactt gaccagaaga
    22981 ttattcagcc atggccagct gatacggaac cagcggcggg tactgctttg tttgcctccg
    23041 aaacggagta cgaaatcacg ataaccatgc ttgcggaagg gaagtcctac atccatgaac
    23101 tccatgtgac ggaatccccg ttcatgggca tcttcaagtg ctttccatac tgccagtatg
    23161 ccgggtgact gcagtgcata ggtctttcgc attcctcctg aaaaccagat aaaagcattt
    23221 tcgccggaat agatgcagac ggagccgccg ataatctttt ccttgtattt tacgatgaat
    23281 atttttgcct gttttcctct gataagcatg ctgttcatgt ggcggaaaaa gtcattggca
    23341 gggaaatatc tccgtattcg tgaagaataa actttgtgca gcatccgcga gaattcctta
    23401 atctcttcca ccgtatgggc ttctactact ttggctccgt ttttgagtcc tttccggatc
    23461 tgacggatac gtgacgggct gaaacggtct tccgctttct gcgtactatg cagagagtta
    23521 cggacacgca gccagttgac tggaaaaaag tcgttctttc ggaagaaacg gtaaccgaac
    23581 atggaattat ccagattgcg gaattcaata agaatgcagg tgcgtgatgc ttcttgtgtg
    23641 agatgctcca gcatttcacc gaaaatttct tcctccttct ctttacttgc cggtagagaa
    23701 gtgtccagaa attcacctgc accatatacc acacattgtt tgacaagaga ggagggaagc
    23761 cactttttgg tcttgcgtat ggcggcaagc aggcgtgcta caggtctgcc ttcttctgtt
    23821 gccactatca gtagcggggt atatccggga gtcgattcat agatctgaaa caactccttg
    23881 gaatgaaaag tattggttcc cggtaaatca ggaatgtctt ttccgcgata atatgttgtt
    23941 agtttaagtg gcatccaaat acaaatttac actttttatt cttcattcaa caataaaaaa
    24001 gagaatttgt tggcttagcc taaaatttgt ctttttatcc tttgcatata tttgaggaaa
    24061 aaaaggcttg aaaaagcgaa tttttgtatt attgtcgtcc tttgtgagta cagaagtaaa
    24121 atggaaacgt ctatgtaaaa gattatgcta attgtatttt actaaacaaa ggaaaattaa
    24181 tattaacttt aaattaaaac gaatgagaga gaatgcattt gttgaagcgt ggaagacaca
    24241 gcatagacgc gtttccatga ttttagggct gactttattg tgtgcccctt ctgccatatc
    24301 tgtttatgca gaaaatggtg tgaatgatat tactgtgcaa gccgtcatgc agacaaagac
    24361 agtgaaagga actgttttag atgaaaatgg agaaccgttg atcggtgtct ctattgtggt
    24421 gaaaggtaca agtacaggta cgataactga ttttgacggt aagttctcca ttaatcttcc
    24481 gggcggaagt aaagaactgg ttgtttctta tatcggatat aaagaacagg ctatcattgt
    24541 gagcggaaat gccccgctga atataaagat ggttccggat acacaggctt tggatgaggt
    24601 agtggtcatc ggttacggta cggtaaagaa acgtgatttg acaggtgcgg ttgcttctgt
    24661 gaaatcagag gatatcacca tgaatccggg cgtgaatccg atggatgcgc tgcaaggtaa
    24721 aattgcaggt ctggatatca ctaattcttc aggtcaggca ggttcgtcac cgacagttca
    24781 gttgcgtggt acccgctctt tgcagttgga tgaggatggt aatatttctt ccgatgcatt
    24841 taagccgact tatattatcg atggtatgcc gggtgatatt gctaccttga atcccaatga
    24901 tattgaatct atcgaagtac tgaaagatgc atcttctacg gctatctacg gttcaagtgg
    24961 tgcgaatggt gttattatcg tgactacgaa aggatccaag agtggaaaac cggtcatcaa
    25021 ttttaatgct tatgccggaa cgactatggg tgcccgagtt cctaagatgc gtacgggtga
    25081 ctcatacatt aattatataa aagattctta taagcctgtc ggtactacta atgaggagga
    25141 aattttcggt gaaagatacg acgccatcaa aaacaaccaa tgggtaaatt ggggagatga
    25201 agtattacat tcaggcttga agcagaacta tagtatttcc gttgccggag gtactgagaa
    25261 gacgaaagct tatttctcgt tgaactatac tgatgagaag agtatgtatg agaatgatga
    25321 ctataaagtg tactctaccc gtgtccgtat agatcaggaa atcaataaat ggatgaatgc
    25381 cggtattaat gttcaggcat ctttctccaa caagaattca cgtaatgccg ttttagaaag
    25441 agcattgttt gctaccccat tgggtgttcc ttataatgaa gatggctcta ttacggaatt
    25501 tccgattccc ggttcatcat cagatccaaa tccgttagca gacgaacaag atggagtata
    25561 taagaataat actaaagcag gaagggctta tgttgacgct tatcttgaat ggaaaccggt
    25621 aaaaggattg tctgtcaagt cacagcttgg aggcagttat tctcaatctc gtgccggtaa
    25681 atttatggga gaaggctctt ataatgtgtt gaaaggcagt acggtggcat atggcgaagc
    25741 taccaataag acgggatata attacaaatg ggaaaacata gtaacttatc acaatacatt
    25801 taataaggat catgacctga cggttacagg ggttacttcc tggaattaca atcagagtga
    25861 agaatattat gtctatggtg aaaacccggc gaccaatgat atgttgtggt atgcattgca
    25921 gaatgctgat aataagaaac tgaacagcaa atatctgatg tcgaaaggga tgggctttat
    25981 cggtcgtgtc aactactcat acaaaggtaa atacctgttc tctgcttcca gtcgttatga
    26041 agcggattcc cgtttgtcga aagacaatag atggaattta ttcccggcag tttctgtagg
    26101 ctggagaatc tcggatgaag catttatggc tggtacaaaa agctggttgg ataacttgaa
    26161 actgcgtgta ggctatggtg ttgccggaac tactgccggt attgctgaat acagttctat
    26221 ggcatctttg gaaaatgtga caacttcttt gggaggaatg actgttccgt cagccaagtt
    26281 tacggagtat atcactaacc gtaatctgac atgggaaaag actcatgact tgaatattgg
    26341 tattgacgcc agcttcctca ataatcgtat tgatctgacg gtggatttgt atcggacaaa
    26401 aacaacggat gtaattcttt cgcaggcatt gccgacatct attatgggta attacacagg
    26461 tagcactact tataaaatga acaagaatgc tgctgaaaca gaaaatcgcg gtattgaact
    26521 tgctcttaat acccgtaata ttgtgaagaa agattttact tggagctcaa cagtgacatt
    26581 taccgccaac aaagaaaaaa ttaaatcttt gatcgaaggg caggatatga tgttcaatgc
    26641 aaaaaagggt gatatggtgt tcaaagtcgg cgaaggagtc ggttctttct atagatataa
    26701 agtgttgggt atctggcaat atagcgaaaa ggaaactgct gctttgttcg gatgcgaacc
    26761 gggcgatatt aagctggatt tacctagtgt gaagaaggac ggaaatggtt actattatat
    26821 gaatcctgaa ggagagcgcg ttgatattac ggcagaaaat ccttatggtg tacgtgcgga
    26881 ttatgatcgt caggtaatag gtcgtaatac tccggactgg acattgggct ttaagaataa
    26941 tttcagatac aaagattttg atttgtctgt cttcctttat gcacgttggg ggcaaatgat
    27001 gaactatggt agtgtgatag gtaaatattc gcctaacccg gattacaata ttcctactta
    27061 ttttacttac tatgacaaga cgatcgaagc agatcagaat gtcttgttct atgctatcga
    27121 taaatccaag gatagaagtg cttatgaagg atatgattcg atgtattatg tggatggatc
    27181 attctttaaa cttaaaaacg taacattggg ttatacgtta cccggtaaac ttacaaaacg
    27241 ttttggtatc agtaatctga gagtttatgc gacaatgacc aacctgttta cttattcgcc
    27301 aaacaaatat gtgaagaatt acgatccgga aatgaacgga agcatcaact tcccattgtc
    27361 tcgtgattgc atatttggtc ttaatttaac tttctaaaaa atagcaatat gaaaaagata
    27421 tatagtttag ttctacttgt tgccggtgtt ttttcttggg gctcttgcag tcttgatgaa
    27481 gtgaacccca acaactcggg tcagttctcc gatggttctt atacattgga aacttataag
    27541 gcattcacca actcgtgcta tacagccttg atcaacaaca tctatcagag tagtgactat
    27601 ctggtttgta cggaagcggg tactgatatt tgggaagaac ctaaatcggg ctccagctat
    27661 cagcgttatc atagttataa cggtatgaaa accgatgata gctattatta taaagtgtgg
    27721 caatattctt atctgtgtat caacagctgt aatattgtga ttgacggagc tgagaatgtg
    27781 acaggggatg agaatgaaat caatgaatgt gtggcacagg ccagatgtct gcgtgcttac
    27841 tattatatga atctggtgga gcagtttgga aatgtcgatt tgcagttgaa ggctgccgat
    27901 agcgagaata tttcttttga tgctcaccgt tctaccgttc ccgaaattta tgctgccatt
    27961 atcgaagacc tgaagtttgc cgtagagaat ctgcccgtaa gtttcagtga ttactatagc
    28021 cgcgttacaa agaaatcggc gatgggatta ttggcacgtg catatattaa tggtgccggt
    28081 tatgatctga aagatatcga tggtgtcagc tttctggaaa aagcctatga tacggcgaca
    28141 accatgatta ataataaagc gatttatgag tggtatatgc atcctgcttt tgccgatgta
    28201 ttcaacgaaa ataataatcg taacaatgaa gaagctctgt tcattgctgc gggtgccgaa
    28261 agaaattcgg acgcttacac caatggtaac tactcacaaa gtgaaatgtt ccgtcacttc
    28321 ttaccttcgt tgggaacata tacggacctg ggtttggtag acaagacttc aaacttcgtt
    28381 tacggtcgtc cgaacagtaa tatcttcctg ccatccaaat atctgatgga ctgttttgct
    28441 gctgatatga acgactctcg ttttcgttat tcatttatct cagcttactc gtcttattca
    28501 ataccggcat ggggggcgac ttatgaatat ggaggttcag cgtgtgccaa agaaatcaca
    28561 agcacacttg ctactaaatt tggtattccc gcatctaata taggtaagaa agtttatcct
    28621 cattttaact tggaatccaa tagtacagcc gatgctaatt actgccagct ggctatctgg
    28681 aatgcagatg gaacagcgaa gactactcag gataaaacag atggtaatat tcttcatcct
    28741 gctatgcctt tagatccggc agaagctcat caatatgccg tttattgttc tttgaagacg
    28801 ctgacagaag aggaaaaagc tcaatatccg gggttggttc ttaatgtttt cgatctttac
    28861 gatgagaatg gaacagccag ggctacctat gacaagccta gtgctgccag tgctttgtgg
    28921 ttatctattt atccggctct ttctaaattc aatatgccgg gtaataagtt tgtcggcaga
    28981 gacgttcaga gaaaaactgt ggatgtgatg atcatgcgta tggcggaagt ttacctgatt
    29041 gctgctgaag catcggtacg cttgaacaag ggagatgctg ccaaatatat taatgtactc
    29101 cgtacgcgtg ccggtgccgg tacggtcagt gagtcgcaag tggatctgaa ttatattttc
    29161 gatgaatatg cccgtgaact ttgtggcgaa tgtggccgct ggtatttgct gaaacgtaat
    29221 gctgcttttg agactcgttt ggctgcttat aataagcgtg ctgccgagca ctttaagaaa
    29281 gaattctatt tgcgtcctat tcctacgaaa tatctggatg cgatcaataa tccggcagaa
    29341 ttcggacaaa acgccggtta ttaatcagtt aattaataat caagcataat taataggagc
    29401 cgggcaggag atttctcttg tccggctctt tgtttccata cctgtatcct gcgtaaaagt
    29461 ttaaaaagga tttccggtat attttcattg tttcctgata cagcttttta ttattttctt
    29521 tatttttgtg tgtccaaaca aaatagcgct atgatagaag aaatgcttgc ttataacaga
    29581 gagttcgtta agaacgaggg atataaagaa tatataacga ataagtatcc cgataaaaag
    29641 attgctatct tatcctgtat ggatacacgt ctgacagctt tactcccggc cgcactaggc
    29701 attaagaacg gagacgttaa aatgatcaag aatgcaggag gcgtcatttc ccatcctttc
    29761 ggtagtgtga ttcgcagtct gcttgtcgct atcttcgagt taggtgtgga ggaaataatg
    29821 gtgattgccc attctgattg tggagcctgc catatgcaca gtgaagaaat gcttgagaag
    29881 atgaaggcac ggggtattaa tgccgattat attcatatga tgagtttttg tggagtcgat
    29941 tttcattctt ggctagatgg ctttgaagat acggagaagt cggtaagggg aacggtcgat
    30001 tttatagttc atcatccttt gattccgtcg gacgtgaaag tgcacgggtt tatcatagac
    30061 tccactactg gagaactgac gcgaattgta taggaaatcg ccctttctgc ctatcaggaa
    30121 ctgcataaaa catggtgtca ctatcgcaac aggatagtgt cactatcact gtctcatggt
    30181 gtcactatgt cattgggata ccgacactat cccaaatgaa aaaaataagg cagcttttta
    30241 tcggctgcct ttatctttct acggttatat actttctttg actcatgcac tcgtttgtaa
    30301 caaacggggt gtccgtgctc tttgatttct gcctcacggc tggctttacg attcgctttg
    30361 atgtaatcgt cttgtgtaat tcgttttttc ataatgaata tatttctcag tgcaaagata
    30421 caatttcatt tcttattacg atcggtttgc gctatctttg catacataaa tcaaatgaaa
    30481 acggaaataa tatggaaaat ttcagtgaac tgataaagaa tcgccgcagt atgcgcaaat
    30541 ttacggatga ggagttaaca caggatgagg ttgtggcact gatgaaagct gccttaatgt
    30601 ctcccagttc caaacgtagt aatagctggc agtttgtggt agtcgatgat aaagaaaagt
    30661 tgaaagaact gtctcactgc aaagaacagg cttcttcttt cattgcagac gctgctttgg
    30721 cgattgtcgt gatggcagat ccattggcga gcgatgtctg gattgaagat gcttctattg
    30781 cttccatcat gatacagttg caggcggaag atttggggct gggaagctgt tgggtacagg
    30841 ttcgcgaacg tttcactgca accggaatgc cgtctgacga gtttgttcat ggaattttgg
    30901 atattccttt gcaactgcag attctttccg tgattgccat tggacataag ggaatggaac
    30961 gtaagccttt caacgaagaa cacctccagt gggagaaaat tcatattaat aagttcggag
    31021 gaaaataacg atgggagctg tcaaagcaaa taataataaa gatacttata aggctactgc
    31081 cgtcgctttt attgtcatcg gaactctttt cctgataaat aaactgctcc cctttgcttc
    31141 tataggtttg ccttgggtga tgaataagga caatttgttg ttgtatgcct ctatcagttt
    31201 tcttattttc aagcgtgaca agtcggtcgg ctttgtgctg ttgggactgt ggctggtaat
    31261 gaatatcggt ctggtaatgt cattgctcgg ttccttgtcc ggttatctgt tgccattggc
    31321 actgttgatc atcggaatta ttttattttg ggtttcaaaa cgttaaagaa acaatgaaaa
    31381 gaagtattga agatacgccc gttgtgtttc tcggtgccgg aaatctggca actaatctgg
    31441 cgaaagcgct ttaccggaaa ggattccgta tcatgcaggt gtacagccga acggaagaat
    31501 cggctcgtac gttagccaat gaagtggaag cggaatatat cactgattta aaaggcgtat
    31561 cgaatgaagc gagattatat attatttcat tgaaagatgc cgctttcgtc gaactgttgc
    31621 ctcagatcac tgatgggaag cagcatgcgc tgctggtaca tacggcaggt agcatcccga
    31681 tgaatatttg ggaaggtcat gcggaacgct acggagtatt ttatccgatg cagacgttca
    31741 gcaaacaacg tgaagttgat tttcgggaag tacctttctt tattgaggca aaaagaccgg
    31801 aagatgccga gctgctgaaa gcggttgccg gtacgctctc tgataaggtg tacgaagccg
    31861 attcggagca acgcagaagt cttcatctgg cagctgtctt tacctgtaac tttaccaacc
    31921 atatgtatgc tcttgccgcc gaattgctgg aaaaatatca tttgccattt gatgtcatgc
    31981 ttcccctgat tgacgaaacg gcacgcaaag tgcatgaact cgctcctcgt gatgcgcaga
    32041 ccggaccggc tgtacgctat gacgagaatg tgatgaataa gcatctttct atgctggcag
    32101 acagtcaggc attgcaggaa atttataaat taatgagtaa aagtatccat gagcaccatc
    32161 aattatgatc tatcccgcat caaagcactg gcttttgatg ttgacggagt attgagttcg
    32221 acaacagtcc cgttgcatcc ttccggagaa ccgatgcgta cagtgaatat caaagacggt
    32281 tatgccattc agctggcggt aaagaaagga cttcatattg ctatcattac cggtggacgg
    32341 acagaagcgg tacgtatccg gtttgcagca ttgggtgtga aggatctgta tatgggttct
    32401 gcggtgaaaa ttcatgatta ccgtgatttc cgtgataaat acggtctgtc tgatgacgaa
    32461 attctgtata tgggcgatga tgtgcctgat atagaagtga tgcgtgagtg cgggttgcct
    32521 tgttgtccca aagatgcagt tccggaagtt aagtcggttg caaagtatat atcttatgtc
    32581 gatggcggtc gtggctgtgg acgtgatgtg gtggaacaag tattgaaagc tcatggcaag
    32641 tggatggcgg aagatgcttt cggctggtga gttgtaaatc actaaatgat aaataaaact
    32701 atgcttggaa atttagataa atatcagatt atattagcct ccaattctcc ccgccggaaa
    32761 gaactgatgt caggcttggg ag
//
