LOCUS       c00045_gnlPro..        24528 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IPJFCJKB_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:47:27
            Original ID  :: gnl|Prokka|IPJFCJKB_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 230842
            Orig. end    :: 255370
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24528
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[240842:245370]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14528
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24528
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24528
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             581..1102
                     /locus_tag="ctg45_197"
                     /transl_table=11
                     /translation="MSFLELARKRCSIRKYAPKNVEQEKIDYILEAARLAPSAVNYQPW
                     YFVWVQSAEGKAKLQECYPREWFKQAPYYLIVCGDHQQSWKRSDHKDHMDIDTAIATEH
                     ICLAAAEQGLGTCWVCNFDTELCRKHFKIPETIEPVVLIPFGYPSDPALFDETPKKRKP
                     IEEIIKRESF"
     CDS             1104..1670
                     /locus_tag="ctg45_198"
                     /transl_table=11
                     /translation="MLYIEVLLLAIGLSMDSLAVSVTGGAVLKNNCTAGNIIKIASVLG
                     IFQAGMTVIGYTMGLGFEKYICAFDHWIAFTLLLYLGGKMIYDSTKEEEEDGKFDPLCN
                     RTLCGLGIATSIDALAVGISLAILKSPLLLQASTIGVVTFAISAFGVYFGNRFGKRIDL
                     KLDLIGGLILIGIGTKILIEHVFFS"
     CDS             1715..3439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ILVD_EDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_199"
                     /sec_met_domain="ILVD_EDD (E-value: 3e-182, bitscore:
                     600.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSQQLRKLAPELDSLRLGSGWKIDELSKPQIIVESSYGHSHPGS
                     AHLDKLMDEAGIGIKEKGGRAANYFVTDICDGEAQGHDGMNYSLVSRDIMAAMMEIHVK
                     ATPFDAGVFIASCDKSVPAHLMAIARLDMPAIFMPGGIMKAGPNLLTLEQIGTYSAQYE
                     RKEITEEQFMVYKRDACPDCGACSFMGTASTMQVMAEALGIALPGSALIPAHLPELKET
                     ARKAGEHALGLAREELKPSDIMTIQAFENAIMVHAAIAGSSNSLLHLPAIAHELGIQLS
                     PDLFDKIHRKIPYLLNIRPSGFWPGEYFWYAGGVPAIMKEIKEFLHLDVKTVTGRTLGE
                     NLKDLQLNGFYENCHKYLPALGVKVGDIIKPLHTPIKAQGAIAILKGNLAPEGAVVKHS
                     AISPRLMQVTLKARVFDCEENAIEAVLQKKIHPGEAVFIRYEGPKGSGMPEMFYTTEAI
                     ASDPELVETIALITDGRFSGATRGPAIGHVSPEASEGGPIALVENDDLIRIDIPARRLD
                     IIGTGGIERSAEEIEKILSERRAHWIKPESQYKKGILDIYTHNSVSPMKGAYMEFFM"
     CDS             3465..4493
                     /locus_tag="ctg45_200"
                     /transl_table=11
                     /translation="MRKNISILVSLLILSLTACSDKGQYFEESGSVFHTSYHIKYKAKQ
                     ILTDKIDSELQRFNLSLNPFNPNSTIAKVNNNEDVEVDEWFTEVFIKAEEISKKSGGAF
                     DITCAPLINLWGFGFSKMDSVTPQMIDSIKAFVGYQKVRLEGKKIIKEDPRILLNCSSI
                     AKGYACDVIARLLEKEGVKNYMVEIGGEVTMKGVNQQGDCWRVGINKPEIGTSGVTNDV
                     EEIVQLCQKGGVATSGDYRNFYIKDGKKYAHTINPATGYPAGQNILSATIVAEDCMTAD
                     AYATTFMVLGVEKAKLLAQSIPQIEYFIIYADNNGQQKVTYSKGMLEYLPNRKTLAILE
                     NP"
     CDS             4502..4879
                     /locus_tag="ctg45_201"
                     /transl_table=11
                     /translation="MKRYLNQLECKILRAGDSLFNSTTTDNLLIFVFSGKLIIYSQEGT
                     HIAEVAKDHFMLLAQNTNHKVIASAPTRLILIHAGSLSDMIINDPEWNVEKPVVLPIPP
                     ALAHTLNQIEYYMKDKYFTLN"
     CDS             complement(4882..5463)
                     /locus_tag="ctg45_202"
                     /transl_table=11
                     /translation="MLENLKKYKIVLASNSPRRRNLLSGLDIDFEVRVISDIDESYPDS
                     IDSMEIPLYIARSKAEAYKPTMADDELLITADTIVWTFDGVMGKPANREEAYAMLHALS
                     DHVHQVITGVCIMTKDKNVGFSVESAVCFAKLGDEEINYYLDKYKPYDKAGGYGIQEWI
                     GYIGVEAINGSFYNVMGLPVQKLYQELKHF"
     CDS             complement(5501..6022)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_203"
                     /sec_met_domain="HAD_2 (E-value: 1.6e-07, bitscore: 25.4,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSINYDLRKIKAFVFDVDGVLSCDVIPLHPNGDPMRTVNIKDGY
                     ALQLAVKKGYEVAIITGGYTEAVQIRFSRLGIQHIYMRSAVKVHDFKDFMEKTGLSPEH
                     IMYAGDDIPDYEVMTRVGLPVAPADAAPEIKEIAKYISSRRGGEGVARDVIEQTMRAQG
                     HWFGEEAFGW"
     CDS             complement(6015..6782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_204"
                     /sec_met_domain="F420_oxidored (E-value: 2e-08, bitscore:
                     28.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVFVGAGNLATRLSLEMRKSGMSIGQVYSHTSEHAKILADELG
                     CGWTVIPEEIVEDADLYVFSLKDAVLQDVIARVKPNNGLWVHTAGSMPISVFEGLTARY
                     GVVYPLQTFSKSREVDFKKIPFFLEANSSEDEKVLGEVARALSSDVRFLSSEKRKNLHL
                     AAVFACNFTNHMYALAEKILEEQQIPGEVLLPLIDETAAKVHVMSPVRAQTGPAIRYDE
                     NVINKHMAMLKDPDMRNLYELISRSIHKEARHE"
     CDS             complement(6779..7339)
                     /locus_tag="ctg45_205"
                     /transl_table=11
                     /translation="MESFATLIQNRRSTRKFTEQLLSPEQVELILKAALMAPASKRSNP
                     WQFVVVEDKEMLKKLAGCKKNGSAFLEGCALAVVVLANVMESDVWIEDASVASIYMQLQ
                     AEDLGLGSCWCQIRNRVTEDEEDSNNYVRSLLDIPYQLDVLSIIGIGYKDQVRKPFDES
                     HLQWEKIHIGKFSLPEENKETGE"
     CDS             7461..9872
                     /locus_tag="ctg45_206"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISIIYSCLGYNKAERIIPSAQADMRLNVQMNYTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKRPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYDP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPNDDASA
                     AMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRKVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRGFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             10001..10411
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_207"
                     /sec_met_domain="Glyoxalase_4 (E-value: 5.3e-26, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             10448..12001
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_208"
                     /sec_met_domain="CT_Btheta (E-value: 2e-291, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12023..12910
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_209"
                     /sec_met_domain="OAD_gamma (E-value: 5.5e-12, bitscore:
                     40.1, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLFALLISFGAKAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCYLTDDKNNPMKYPIPKGDVLTQIQPRQHTLFWADGQP
                     DRGTFHVNFVLDPSKENYIALYDADGKTLIDEVTIPAGQMADISYGRVIDGKDEWAQLK
                     KVTPSTNNLTLDSNEKIDNFKQNDSLGIGMTITAMAVVFLGLFLLYIIFKQIGRLSISA
                     SKRNAQKAAGTTSVSVDAGQESGEIFAAIATALYEMSDDNHDIEHTVLTIHKVQRTYSP
                     WSSKLYGLRQTPHK"
     CDS             12932..13363
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.8; E-value:
                     1.6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_210"
                     /sec_met_domain="Biotin_lipoyl (E-value: 6e-20, bitscore:
                     64.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIADVEVNGTPYQVKLEKPAKKQ
                     MVTLKRPAQAPTTASGDPVVTRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLII
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             13368..14528
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_211"
                     /sec_met_domain="OAD_beta (E-value: 1.8e-152, bitscore:
                     501.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLTFLGENLQLFLTYTGVYNATPGHLIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYTIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKLFNLILKDGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(14595..14741)
                     /locus_tag="ctg45_212"
                     /transl_table=11
                     /translation="MRKKSVNTLLVFGVVVAIILLMIWLFLGTTLVEDTSTEISPVPIE
                     QAN"
     CDS             complement(14810..15526)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_213"
                     /sec_met_domain="Peptidase_M22 (E-value: 6.8e-27, bitscore:
                     88.7, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYME
                     EALEAAKSKGMKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILASAA
                     IRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGKVCF
                     FGDGAAKCEMVITSPNACFMAGIYPLAVNMASLSQKAYDDGRFENVAYFEPFYLKEFQA
                     TIAKNKVLNEALGKNK"
     CDS             15728..16588
                     /locus_tag="ctg45_214"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMEL
                     RSLLLQSLERGKVEFNIFIEYIGKDTPTQINLAAVENYYNQIKEIAEKLNISVPNDWFQ
                     TLLRMPDAIKSETVEPDESEWGVVLETVKDAIKHLCDFRIQEGAMLQKLFEQKIANIAT
                     LLKEVEKYEGERIEKIKARIMDNLQKIAEKDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
     CDS             16603..17169
                     /locus_tag="ctg45_215"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINYLLKQDLHLRFSISATSRAPRGTE
                     KNGVEYYFLTPEEFRSRIANGDFLEYEEVYTDKYYGTLKSEVERILNEGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPCIDDLRKRLEGRGTDSPEVIESRIAKAEYELGFTGQFD
                     KVVVNDDLETAQKDALKIIREFLNK"
     CDS             17173..17352
                     /locus_tag="ctg45_216"
                     /transl_table=11
                     /translation="MSNIFKNTRFMMGLSIVCGIASLVLGGISLYYKEYIIGGALIFNI
                     FICFINYKGWQKKG"
     CDS             17364..17939
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_217"
                     /sec_met_domain="CTP_transf_like (E-value: 1.7e-23,
                     bitscore: 77.3, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKTGIYSGSFNPIHIGHLALANWLCEFEGLDEVWFVVTPHNPL
                     KKKDDLLDDSLRLEMAQAAIDGCPKFRVCDIEFYLPKPSYSIDTLRTLSRNYPNRDFYF
                     IMGADNWQLFPRWKEHEKILQDYKLLIYPRLGFDISIPAIYPNVKKVDAPLMEISSTFI
                     RNAYQTGKDIRFFLPEGVRPYFGSVANQ"
     CDS             18858..19037
                     /locus_tag="ctg45_218"
                     /transl_table=11
                     /translation="MIYLLFLVTLLLISCNPDQAKDNGKDETIEYFIPLSHRVEKDVDE
                     MFEEYRYVPLGNKG"
     CDS             18988..19974
                     /locus_tag="ctg45_219"
                     /transl_table=11
                     /translation="MKCLRNIGMSPLETRDDALIDVLYNVKNIAIFQEDIYIGSGEQLI
                     VWDKYGKFKRVLSKKGNDPQSYLHFNHFMIWPNGDLSIASPIEIVTYSNSHQFINKKRC
                     ENVGYIEAITLLNDSLYIIKCMPTPEQLRYRIINHHTGAIINSYDSIINCNRYISSFTN
                     SFERYEGHIISHGYQSNDILECTLDSSKIRYKINVDNRIPPAGFYTQEGKEGMQLIQEE
                     AEKGYIGHIPDYVESKETILLSFKGKREDLNGIALIDKKDGNARVLENIKFDDNFRWLP
                     KQFFSLDEGWCAMLMYPEDVLKKEEFARRFPGLDEESNPVLFIGKLR"
     CDS             19994..20506
                     /locus_tag="ctg45_220"
                     /transl_table=11
                     /translation="MEHDNLFIQILEILSIKYTEDFTIRFYESHPHKNNLFGLSEMLRY
                     YNIENVAAEIQKTQENLSSLDVPFVAYVDHEFVLVRHVSTEAIIYSWRGKNITLSIPVF
                     LERWSGIVLLFESTDESINRIIKNIERILTTADSNRMFRIITSIINRVCPYHQQRNGDR
                     NLGVMGC"
     CDS             20472..21539
                     /locus_tag="ctg45_221"
                     /transl_table=11
                     /translation="MEIGIWGLWGVNVIGASFCGILLSREILGSDKYVNKICSLFLKSS
                     DCNGTLDSQASHFLGISWSVFGLGYFLSAILFIALLPQYVIYAETLNIIALPYTAWSVW
                     YQKFRVKQWCALCLSVQATVWITFLISLFAIGMDFNQWDLFDFTTIGCVYGLVILSLHF
                     TVTLYVKEKQIQRSNNKLSSIKLNASVFKSLLNEQPQYDIDKNTGILLGNRDAKEWITI
                     ISNPHCAPCVKLHLQIEKLLKEYKEEICIQIILTSFSKELEPSAMLLTSMYLLNNESDY
                     LRFLSDWYAKGRHKKEDCYKRYRLNPNDKDMLANFQAQNEWVRRNTISSTPTVLTNGYL
                     LPEEYELKDMSYLIN"
     CDS             21569..22570
                     /locus_tag="ctg45_222"
                     /transl_table=11
                     /translation="LIGSLHTSYPFGLAHGKMGSLIYLYHLYDYTQEAIYKEKAERLLD
                     DLLENDLSKNAELTVEEGLCGVALGLDYIVKKQFVDGDINDLLSGIDDLLFKKLVFGNM
                     ESRYSLSQLIHFLYYIYKRLEIQTNDNERFPFEGLAIKLVNQLADLIDASFFEESYTFS
                     IYQYHVPILMKTLSCLIQYDFYKDRIQKVLEQLSLYMFSHLPHLHLNRLYLLWGILPLR
                     NCSPDWQRYVNELRKSINLDIIYNREIKGKDIYISNGYASLYFLLEGLKRDFPEYTIPF
                     NPHLIYDRIISSDAWDALMENEYYYNIHRGLLNGFPGTVLALLNIKQRYLCE"
     CDS             22561..23250
                     /locus_tag="ctg45_223"
                     /transl_table=11
                     /translation="MRIDLTDTTFIIPVRIDSMIRLENLLMSVDSIVRYFRTRILILEA
                     SSYQNEIIPSLIKDDTVKYTFLVDKDPVFYKTKYLNILAKQVDTPLVCIWDADVILDHL
                     QILDAVKQLRTRTSDVAYPYDGNFLDTSDILREHYWLHRDLDFLKKHQAKMNSLYTVEG
                     VIGAVGGAVFAQTEKYLQAGMENEDFYGWGLEDGERHYRWLSFGYRIYRSEGCLFHLSH
                     PRDQNGM"
ORIGIN
        1 aaagatatga cccgttgtct aagacgatcc ccacgaaatt attcaacgcg acagctcgta
       61 aattctcggg aataaagaac ttacacgatt tcaattgcgg attgaaagcg tataagaatg
      121 ttgtcattaa aaatatagag gtgtataacg atatgcaccg ttacatacct tatttagcta
      181 agattgccgg atttcacaag attggcgaga aagtagtgaa acatcaagcc cgcaagtacg
      241 gaactactaa attcgggttg gatcgcttcg tgaacggtta tcttgatttg atcacgcttt
      301 ggtttacttc caaattcgga aagaaaccga tgcacttctt cggtttatgg ggaagcgcta
      361 tgttcttcat tggttttatc gctctagtaa tcgtactcag catgaaattg atctcgatgt
      421 actctggaga tctaagacct ttggttacaa gttcccctta tttctatatt tcattgacag
      481 cgatgattct gggaacccag atgttcctag cgggctttat cggggagttg atttcccgca
      541 attctccgaa tcgcaataac tataaaatag aggatgagat atgagtttcc tagaattagc
      601 gagaaaacgt tgctctatcc gaaagtatgc ccccaaaaac gtagagcaag aaaagattga
      661 ttatatccta gaagcagctc gtttggcccc ttcggcggta aattatcaac cttggtattt
      721 tgtatgggtt caaagtgcgg aaggaaaagc taaattacaa gaatgctatc cccgggaatg
      781 gttcaagcaa gcgccttatt acttgatcgt ttgcggagat catcagcaat cttggaaacg
      841 gagcgatcat aaggatcata tggatatcga tacggctatc gccacggaac acatttgttt
      901 agccgctgcc gaacaaggat tgggtacttg ttgggtttgc aatttcgaca cggagctttg
      961 ccgtaaacat tttaaaattc cggaaacgat cgagcctgtt gtactgatac cgttcggcta
     1021 tccttccgac ccggcattat tcgatgagac tccaaagaaa cgtaagccca tagaagaaat
     1081 tattaaacgg gaatcattct agtatgttat acattgaagt tctgctacta gcgatcggct
     1141 tatccatgga tagcctagca gtatcagtta ccggcggcgc agttcttaag aacaactgca
     1201 ccgccggtaa tattattaag atagcgagcg tgctcggtat attccaagcc ggaatgaccg
     1261 tgattggtta tacgatggga ttaggattcg aaaaatacat ttgcgccttc gatcattgga
     1321 tcgcatttac cctcttgctt tacttaggtg gaaaaatgat atacgatagc acgaaggaag
     1381 aggaggaaga cgggaaattc gatcctctat gtaaccggac attatgcgga ttgggaatag
     1441 cgacaagtat cgatgccctc gccgtaggaa tctctctggc gatcttaaaa tcaccgctct
     1501 tgctgcaagc ctcgactatc ggtgttgtca ccttcgctat ctctgccttc ggcgtctatt
     1561 tcggtaaccg attcggcaag agaatcgact tgaagctgga cctcatcgga ggtttaatct
     1621 taatcggtat cggtacaaag attttgatag agcatgtatt ctttagctag ggatacctta
     1681 ttgaataaat aaccttatac attaattaat agacatgaaa agccagcaat tacgaaaact
     1741 agcgccggag ctggattcac tccggctagg cagcggttgg aaaatcgacg aattgagtaa
     1801 accgcaaatc attgtagaaa gcagttacgg acatagccat ccgggaagcg cccatctgga
     1861 taaattgatg gacgaggccg gaatcggtat aaaggaaaag gggggacgtg ccgcaaacta
     1921 cttcgtcact gatatttgtg atggagaggc gcagggacac gatggtatga actactcatt
     1981 agtctcccgt gatatcatgg ccgccatgat ggagattcat gtaaaagcga ctcctttcga
     2041 cgctggtgtc tttatagcca gttgcgacaa atccgtccct gcgcatttga tggcgatagc
     2101 ccggctagat atgcctgcta tattcatgcc tggtggtata atgaaagccg gtcccaacct
     2161 actcacgtta gaacaaatcg gtacctatag cgcccagtac gagcgaaaag aaataacgga
     2221 agaacaattc atggtttata agcgtgacgc atgtccggat tgtggagctt gctctttcat
     2281 gggcactgcc tctacgatgc aagtaatggc agaagcgcta ggcatcgctt taccgggttc
     2341 cgccttgatc cccgcccatt tacccgagtt aaaagaaacc gcccgtaaag ccggagaaca
     2401 tgcgctcgga ctggcgagag aagagttaaa accctccgat atcatgacga tacaagcgtt
     2461 tgaaaatgcg atcatggtac atgccgccat agcgggttcc agcaacagcc tgcttcatct
     2521 tccagctatc gcccatgaac tgggaatcca gttatcaccg gatttgttcg acaagataca
     2581 tcgtaagatc ccctaccttt taaatatacg tcccagcggt ttttggcccg gcgaatattt
     2641 ctggtatgcg ggaggcgtac cggcgatcat gaaagaaatc aaggaattcc tccatctcga
     2701 tgtcaagacc gttaccggca gaacattggg agaaaactta aaagatttac agctcaacgg
     2761 cttctatgag aattgccata aatatcttcc tgccctagga gtaaaggttg gcgatattat
     2821 caaacctctt cacacaccga tcaaggcaca aggagccatc gctatattga aaggaaattt
     2881 agcgcccgaa ggggcagtcg taaaacattc ggcgatttca ccccgcttga tgcaagtcac
     2941 cctgaaagcg agggtattcg attgtgagga gaacgctatt gaggcggtat tacaaaagaa
     3001 aatccacccg ggagaagcgg tatttatccg ttatgaagga ccgaaaggaa gtggaatgcc
     3061 agaaatgttt tatacgacag aagcgatcgc ctccgatcct gagttggtag agaccatcgc
     3121 attgatcacc gacggtcgtt tctccggagc gacccgaggc ccggcgatcg gacatgtatc
     3181 cccggaggct tccgaggggg gaccgatcgc cttggtagag aacgatgact tgatccgtat
     3241 cgatattcca gcgagaagat tggatataat cggtaccggc ggtatcgaga gaagcgcgga
     3301 agaaatagaa aagatcctat ccgaaaggcg tgcacattgg ataaaaccag agtcacaata
     3361 taaaaaagga atccttgata tttatacaca caatagcgtc tcccccatga aaggggcata
     3421 tatggaattt tttatgtaag ttcgcgacat aaaatttcat aatgatgcgc aagaatattt
     3481 ccatattagt cagcctgttg atcttatcgc ttacggcttg ctcggacaag ggccaatatt
     3541 tcgaagagag tggttctgtt tttcatacaa gttaccacat caaatacaag gccaagcaaa
     3601 tcctaaccga taagatcgac agcgagctgc aacgttttaa cctctcctta aatcctttca
     3661 accccaactc cacgatcgct aaagtcaata ataacgagga tgtggaggta gatgaatggt
     3721 ttaccgaagt attcattaag gcggaagaaa tctccaaaaa atcaggagga gcttttgata
     3781 ttacttgcgc tccattaatt aatctatggg gattcggatt cagtaagatg gacagcgtaa
     3841 ccccgcagat gatcgatagc atcaaggctt tcgtcggtta tcaaaaagta agattggaag
     3901 gaaagaaaat catcaaagaa gatccccgga ttctattgaa ttgttcgtcc atcgcaaaag
     3961 gttatgcttg cgatgttatc gcccgcctgc tggaaaaaga aggcgtaaag aactacatgg
     4021 tagaaatagg tggtgaggtc accatgaaag gcgtaaatca acaaggtgac tgttggcgag
     4081 tcggcatcaa caagccggaa atagggacaa gtggcgtaac aaatgatgtt gaagagatcg
     4141 tacaattatg ccaaaaaggg ggggtggcta cttctggtga ctaccgaaac ttctacatca
     4201 aggatggtaa gaaatatgcc catacgatca atccagcgac cggttatccc gctggacaaa
     4261 atattcttag tgcgacaatc gtggcggaag attgtatgac agcagacgct tacgctacga
     4321 ctttcatggt tttgggagtc gagaaagcga agctactggc acaatccatc ccccaaatag
     4381 agtatttcat tatttatgcg gacaacaacg gacaacagaa agtcacctac tcaaaaggta
     4441 tgttggaata ccttcctaac agaaaaacat tggctatcct cgaaaatcct taagttccta
     4501 catgaagcgt tatctaaatc aacttgaatg caaaatactg agagccggag attccctgtt
     4561 taattccaca accacggata acctattaat cttcgtattt tcgggaaaac ttattattta
     4621 cagccaagaa gggacacata tagcggaagt ggcaaaagat catttcatgc tacttgcgca
     4681 aaacaccaat cataaggtta tagcctcagc ccctacccgc cttatcttaa tacatgcggg
     4741 cagtctatcc gacatgatca taaatgaccc ggaatggaat gtggagaaac cggtcgtctt
     4801 accgattccc ccagccttag cgcacacatt aaatcagata gaatattata tgaaggataa
     4861 atactttacc ttgaattgag attaaaaatg tttcaattcc tgataaagct tttgcacagg
     4921 taatcccatc acgttataaa aactaccatt gatagcctct accccgatat aaccgatcca
     4981 ctcctgaatg ccataccctc ccgctttatc ataaggttta tatttatcca aataataatt
     5041 aatctcttca tcacccaatt tagcgaaaca aaccgcagat tcgacggaaa agcctacatt
     5101 tttgtccttc gtcatgatac aaacaccggt tattacctga tgtacatgat ccgacaaagc
     5161 atgaagcata gcataagctt cctctcgatt cgcaggcttt cccataaccc cgtcaaacgt
     5221 ccaaacgatc gtatctgccg tgattagcaa ttcatcatcc gccatagtcg gtttataggc
     5281 ctccgctttc gaacgggcaa tatataaagg gatctccatg gagtcaatag aatccggata
     5341 agactcgtca atatccgaaa ttaccctcac ctcgaagtcg atatccagac cagataacaa
     5401 attccgtcgt ctcggagaat tagaggctaa gacgatcttg tactttttta aattctctaa
     5461 cataacctat tcgattaagc gttacacatt caccaaaatt ttaccaccca aaagcctcct
     5521 cgccgaacca gtgtccttga gcccgcatcg tttgctcgat cacgtcccta gctacgcctt
     5581 cgccacctcg ccgggaggat atatatttcg ctatctcctt gatctccgga gccgcatccg
     5641 caggcgccac cggcaatccg actcgcgtca ttacctcata atcaggaata tcatcacccg
     5701 catacatgat gtgctcagga gacaagcccg ttttttccat gaaatcctta aagtcatgca
     5761 cctttacagc gctacgcata taaatatgtt gtattcctaa acgagaaaag cgaatctgta
     5821 cggcttccgt atatccgccc gtaattatag cgacctcata acctttcttc acggccaatt
     5881 gcaaggcata gccatccttg atattgacag tacgcatcgg atcgccattc gggtgaagcg
     5941 gaatcacatc gcaggatagc accccgtcta catcaaagac aaaagccttt atttttctca
     6001 aatcatagtt tatactactc atgtcgagcc tccttatgta tacttcggct aatcagctca
     6061 tatagatttc gcatatccgg atctttaagc atagccatat gtttgtttat cacattctcg
     6121 tcatatcgta tagctggtcc cgtttgggct cgcaccggcg acattacatg taccttagcg
     6181 gctgtctcgt ctatcaaagg tagcaagacc tctcccggta tttgctgttc ttccaagatc
     6241 ttttcagcta gcgcatacat atgattcgta aaattacaag cgaaaaccgc cgctaaatgt
     6301 aagttctttc gcttctcgga ggagaggaaa cggacatcac tggagagcgc cctagccacc
     6361 tcgcccagca ccttctcatc ttcagacgag ttcgcctcta aaaagaacgg tattttcttg
     6421 aaatccactt ccctactctt actaaacgtt tgtaacggat aaaccacccc atatctagcc
     6481 gtaagacctt caaatacaga gataggcata ctccctgccg tatgcaccca caaaccgtta
     6541 ttcggtttta cacgggcgat aacatcttgg agcacggcat ctttcaaaga gaaaacatac
     6601 aagtcggcat cttccacaat ctcttccggg atcacggtcc acccacatcc caattcatca
     6661 gctaaaatct tagcatgctc gcttgtgtga ctatatactt gcccgatact cattccagac
     6721 ttacgcattt ccaacgaaag ccgggtagct aagtttccgg caccaacaaa tacgactctc
     6781 attctcccgt ctctttattt tcttccggaa gagagaactt tcctatatgt atcttctccc
     6841 attgtaaatg ggattcatca aaaggcttac gaacctgatc cttataaccg ataccaatga
     6901 tagacaagac atccaattga taagggatat ccagcaacga acgaacataa ttattcgaat
     6961 cctcctcgtc ctctgttacc cggttccgga tctgacacca gcaactgccc aatcccaaat
     7021 cctctgcttg caattgcata taaatagaag cgaccgaagc gtcctcgatc caaacatcgc
     7081 tttccatcac attcgccaag acaaccacgg ccaaggcaca accctccaga aaagcggaac
     7141 catttttctt acacccggca agtttcttca acatttcctt atcttccacg accacgaact
     7201 gccaaggatt actacgtttt gaggccggag ccatcaacgc cgccttcaag atcagttcta
     7261 cctgctcggg tgaaagtagt tgttcggtaa acttacgtgt acttcttcta ttttgtataa
     7321 gtgttgcaaa actctccatt tttttcgttc tttgtactct tttaatatta agattcgcaa
     7381 atataaatat aattttttgc acccatatat acgtatcgtt cttttttctc gttagtattt
     7441 ttataattga acaatagatt atgaagattc gtgcgatagc cgcgctgcta tttatactta
     7501 tttccgtgag tgcctttggc gaaggccgca taaaaatcac tggttatgtc cgtgacgccg
     7561 acggtaaccc tctggaatta gtgaatgtcc gggttaagaa cacgttgatc ggctccatga
     7621 ccaacgagaa gggatattat tccttttcca tatcgccggg ggattctatc tccattattt
     7681 actcttgtct gggatataat aaagctgaac gtatcattcc ttcagcacaa gccgatatgc
     7741 gcctgaacgt acagatgaac tatacctcat ttgatttagg ggaagtatct gttactgcca
     7801 tccgcaagca gaccacgacc atggagtccc taaatgcgga caaaatcaag ttattgcccg
     7861 atccttccgg aggtagtata gagagcttgg tcgttacgtt tgccggagta tcgtccaata
     7921 acgagttaag ttcccagtat tccgtacgtg gaggtagtta tgatgaaaat atcgtttatg
     7981 tgaatgggat cgaggtattc cgtccacttc tgattcgctc gggacaacaa gagggcctta
     8041 gctttatcaa tccggaccta acggaggcgg tcaatttcgc cgccggtggc ttcgaggctc
     8101 gttacggaga caagatgagt tctgtgctgg atattaccta taaaagacct aagatattcg
     8161 aaggctcggc ttctgcgagc ttgttgggcg cgaatgctta tgtaggcagt tctatcggta
     8221 aatttaccca agtaacgggt ttccgcttta aaagcggtcg gtctattttg ggtaccatgg
     8281 atacagacgc agaatacgac cctaaattta tcgatttgca aacttacatc acgtaccaat
     8341 tggcccctaa atgggaaatc aatttcttgg gaaacctcgc taacaataat tataaattca
     8401 ccccttatag ccgggaaacc tctttcggta cagccgagca tcccaagaac ttcaaagtct
     8461 atttcgacgg aagggaaaga gaccgtttcc aaaccttatt cggtgcgctt acattgaaac
     8521 acaaccccaa tgagaacaca gagttgggac ttcaagcctc cgctttcaaa agcaaggaag
     8581 aagagggata cgatatcgcc ggagaatatt ggctgagcga gaacggagcg gaaaatccga
     8641 atgacgacgc gtcagccgcc atgtccgtag gccgttatca cgagcacgca cgaaaccgtt
     8701 tgaactccac cgtcatgaat gtcgggcact atgggatggc ccgcctttta aacaatacgt
     8761 tgaaatgggg agccacggta caaatggaga aaatcaatga taagatcagt gaatgggaaa
     8821 aaagggattc ctcaggttat tctttgcccc aaaccggtaa taacgtaagt gtatattcga
     8881 acctcttttc tgataatcag atagaaagca cacgcttttc cgcttatgcg caagacgcat
     8941 tcaaattcag gaccaagcaa ggtctgttca cgttagtcgc aggggttaga ggtagttatt
     9001 ggacttataa taaggagttc cttttcagtc cccgtgcctc attgggcttt atcccgaact
     9061 tcgaccaaga cttgacgctc cgtttcgcca ccggactgta ttatcaatcg cccttctaca
     9121 aggaattacg taaagtagac aaagataaga acggcaataa tatcacggta ttgaacaaag
     9181 atctaaagtc acaacgctcc atccatttca tattgggagg agattatacg ttccgtgccg
     9241 tagaccggaa tttcaaggtg accgccgaga tgtactataa aaagctggac aatctgaatc
     9301 cctacaccgt agataacgtc aagatccgct attacggtga gaactgcgcc aaaggttacg
     9361 ccatgggact cgatgtcaaa ttcttcggag aattcgtacc gggtaccgac tcatggatca
     9421 gcttctcctt gatgaaagcc cagcaaacca tccgggaaac aacgaccgtt cctatggcca
     9481 atagccaagg ctacaacatc tcactcttct tccaagatta tttcccgggc tataaacgag
     9541 tcaagctaaa tctgaaagga gttctatccg gaggacttcc ccagacaatc ccgggcaaag
     9601 gatacgaagc cggctatttc cgtacgcccg cctacaaacg tgtagatatc ggcctctcct
     9661 atcaattggc aggaggcacg gacgctatca tggacagggg cttcttccgc catttgaaaa
     9721 acatttggct aggtctggat gtgtttaaca tattagacat caaaaacgtt agttcctact
     9781 attggataac agatgtatat aatgtccaat acgcagttcc aaactatctg accggacgtc
     9841 aattgaacgt tcgtctgatt gtcgattttt aataaaatgt atctttaaac acatttactg
     9901 ggagataaaa acaaaaaatt atttcctcat tcataaaaag tagtgtacat ttgcacacaa
     9961 tagaaacaaa catttactaa atctttaaat tattattgac atggaactta cacatatcga
    10021 acatttaggt atcgcagtga agagtatcga ggcttgttta ccctattatg aaggcgttct
    10081 tggattaaaa tgctacaata tcgaagtagt agcagaccaa aaagtaaaaa ccgcattttt
    10141 caaggtagga cagactaaga ttgaactact agagccgacc agcgaagata gcacgatcgc
    10201 gaaatttatc gagaaaaaag gtgaaggtat ccaccatatc gcattcgcgg tacctgatgt
    10261 acaggcagct ttgaacgagg ctgaggaaaa aggcgttaaa ttaatcgata aagctcctcg
    10321 tggtggcgcg gaaggcttga acatcgcttt ccttcacccg aaatcaactt gcagcgtatt
    10381 gacagaactt tgcatgccgg gcaacaaata attaatccgt tcatttctaa caacaaatca
    10441 aaatacaatg agtaaccagc ttgaaaaagt aaaagagctc atcgcacttc gtgagcaagc
    10501 tcgcttgggt ggaggagaga aaagaatcga atcacagcac aaaaaaggca aatataccgc
    10561 tcgtgagcgt atcgccatgt tgcttgacga aggtagtttc gaggaattcg acatgtttgt
    10621 tcaacaccgt tgtacaaact tcggtatcga gaaaactaaa tatttaggcg atggtatcgt
    10681 aacaggttat ggtacgatcg acggacgttt ggtatatatc ttcgctcaag atttcaccgt
    10741 attcggtgga gccttgtctg aggctttggc tatgaaaatc tgtaaagtaa tggatcaagc
    10801 catgaagatg ggcgctcccg ttatcggttt gaacgactct ggtggagctc gtatccaaga
    10861 aggtgtaaac gccttggcag gatacgcaga gattttccaa cgtaacatct tggcttccgg
    10921 tgttgttcct cagatttccg gtatcttcgg cccttgcgcc ggtggagccg tttattctcc
    10981 ggctttgaca gacttcaaca tcatgacacg tggtaccagc tatatgttct tgactggtcc
    11041 gaaagtcgta aaaaccgtaa caggtgagga tgtaacccaa gagcagttgg gtggagccag
    11101 cgtacacact acaaaatcgg gtgtagccca tttcgctgtt gatacggaag aggatggttt
    11161 gcaattgatt cgtaaattgc tcagcttctt acctcagaac aacttagagg aaacgccgtt
    11221 agttgagtgt aaagacccga tcgatcgttt ggacgatgta ttgaatgata tcattcccga
    11281 taacgctaac caatcttacg atatgtatga ggttatcggt acaatcgtcg ataacaacga
    11341 gtttctagag gttcatgcgg attacgctaa gaatatcatc gtaggtttcg ctcgtttcaa
    11401 cggacaatct gtcggtatcg tagccaacca gccgaaggtt atggcaggat gcttggatag
    11461 caacgcatct cgtaaagcag gtcgcttcgt tcgtttctgc gacgctttca atattccttt
    11521 ggtaacattg gttgacgttc cgggattcct tccgggtaca ggtcaggaat acaacggtgt
    11581 aatccttcat ggcgctaaat tgctttacgc ttatggtgag gccaccgttc ctaagattac
    11641 cgttacattg cgtaagtctt acggtggagc ttattgcgtg atgagttcta aacatttacg
    11701 tggtgatatg aattacgcat ggccgacagc cgagatcgct gttatgggcc cgagcggtgc
    11761 cgtagaggtt atcttcgcca aggaagtagc agccgctgaa gatccgaaag catgcgcagc
    11821 agagaaagaa gctgaatata agaaagcatt cgctaatcct tataacgcag ctcaatacgg
    11881 ttatatcgac gatgttatcg aaccacgtaa cactcgtttc cgtattattc gtgctttgca
    11941 gcaattgcag actaagaagt taagcaatcc tgctaagaaa catgataacc tgcctctata
    12001 atccgtaaaa caggagatga atatgataaa taagaaaata ggggtattgc tactgttcgc
    12061 tttgctcatt tcattcgggg caaaggcaca gcgcgcaacc tccatgcgaa ttaatgaagt
    12121 attggttatc aacgaggata acttcgttga tgactatggc aaacgtcatg gctggattga
    12181 gttgttcaac acttcggccg gaacggtaaa tatcgcggga tgttatttga cagacgacaa
    12241 aaacaatccc atgaaatatc cgatcccgaa gggagacgta ttaactcaga tccaaccccg
    12301 ccagcacaca ctattttggg ctgacggaca gccggacaga ggtacattcc acgttaactt
    12361 cgtattagat ccctctaagg agaattatat agctctgtat gatgcagatg gtaaaacatt
    12421 gatcgacgaa gttacgatcc ctgccggaca aatggctgat atcagttacg gtagagtgat
    12481 cgatggtaaa gatgaatggg cacagctgaa gaaagttact cccagtacga ataacctaac
    12541 attggattct aatgagaaaa tcgataattt caaacagaat gactctttag gtatcggtat
    12601 gaccattacc gctatggctg tagtgttctt gggattattt ttgttataca tcatctttaa
    12661 gcagatcggt agattgtcta tatccgcaag caaacgtaac gctcagaaag ctgcgggaac
    12721 aacaagtgta tcggttgacg ccggacaaga gtctggtgag atcttcgccg ctatcgctac
    12781 cgctttgtac gagatgagtg atgacaatca tgacatcgag cacacggttc ttacgatcca
    12841 caaggtacaa aggacttatt ctccttggag ttcaaaactc tacggtttgc gtcaaacccc
    12901 acataagtaa ttatctaaaa acgaacaaag aatgaaaagt tttaaatata ccattaacgg
    12961 taacgtatat aaagtacaca tcaattctgt agtggatgac atcgcagatg ttgaagtaaa
    13021 tggtacacct tatcaagtaa aattagagaa accggcgaag aaacaaatgg ttacattgaa
    13081 acgtccggct caagcaccga caacagcaag tggcgaccct gtagttactc gtccggcagc
    13141 ctctactaca caaggcgctg ttaagactcc gctaccaggt gttatcttgc aggttaagtg
    13201 caacgtaggt gatacagtga agagaggtca aacattgatt atccttgagg ctatgaagat
    13261 ggagaacaac atcaacgcag accgtgacgg taagattata gaaattaaag tacacaaggg
    13321 agactctgtg ctagaaggtg ctgatctcgt agtaatcgga taagactatg caagagagct
    13381 ttttaacatt cttaggtgag aacttacaac tgttccttac ctatacaggt gtatacaacg
    13441 ctactccggg acatctcatc atgattctgg taggtctgtt gtttatattc ctggcgatta
    13501 aatatgagtt tgaaccgatg cttttgatcc ctatcggatt tggtatcttg atcggtaata
    13561 ttcctttcaa ggacgcaggt cttcaggtag gtatttatga gcaagggtct gtactgaaca
    13621 tcctctatca gggtgtgacc tctggatggt atccgccatt gatcttcctc ggtatcgggg
    13681 ccatgaccga cttctccgca ttgatctcca atcctaagtt gatgttgatc ggtgcagcgg
    13741 ctcagttcgg tatctttggt gcttatacga ttgctcttca aatgggattt gagccgaacc
    13801 aagcaggtgc tatcggtatt atcggtggtg ctgacggtcc gacggctatc ttcctttctt
    13861 ctaagttagc gccaaactta atgggtgcga tcgcggtatc cgcttactca tacatggcgt
    13921 tggttcctat tatccaaccg ccgttcatga gattgcttac gactaagaaa gagcgtttga
    13981 tccgtatgaa accgccgaga gccgtttctt ccacggaaaa aattatcttc ccgatcgttg
    14041 gtttgttgct tacttgcttc ttggttccgt ccggtttacc attgttaggt atgctattct
    14101 tcggaaactt attgaaagaa agtggcgtga ctcgtcgttt ggcagagact gctcgtggtc
    14161 cgctgatcga tacaatcacg atcttattgg gtatcacggt aggtgcttct acccaagcta
    14221 ctcaattctt aacattgaac tctatcaaga tcttcggttt aggagcattg tctttcgtga
    14281 tcgcgacttg tgccggtgta ttgttcgtta aattgttcaa tttaatattg aaagacggta
    14341 acaagattaa cccgcttatc ggtaacgctg gtgtatctgc tgttccagac tcagctcgta
    14401 tctctcaagt cgtaggtttg gaatatgacc cgaccaacta cttgttgatg catgctatgg
    14461 gtccgaacgt agcaggtgta atcggttccg ctgtagctgc cggtatcttg ctaggattcc
    14521 ttggttaata aaacaactat ctatattaaa aaaggcgagg tccgaaagga tcccgccttt
    14581 ttatgttatt gttctcagtt agcttgctct ataggaaccg gactaatctc cgtactcgta
    14641 tcctccacca acgttgtccc gaggaacaac cagatcatca aaaggattat agcgacaacc
    14701 acaccaaata ccaatagcgt attcacactt ttctttctca tgtctttaac tgatttattc
    14761 attttagaat aaacagccgg aacatgaatt tggttgtgta cccttactct tatttgtttt
    14821 tccctaacgc ctcgttcagc actttgttct tagcgatcgt tgcttggaat tctttcaaat
    14881 agaaaggctc aaaataagcc acattctcaa aacggccatc atcatatgct ttctgcgaca
    14941 aggatgccat atttacagcc aatggataga taccagccat aaaacaggcg ttcggagaag
    15001 tgattaccat ctcacattta gcggcaccgt ctccaaagaa acaaacctta ccgttctcta
    15061 aaaaagaagc atacgaatca gcatctacga tatcagcagt cgtggcacgt atcgtgttga
    15121 gatgggaatc ataaatcgaa gagtagactt ccatacggcg ggcatccaac atagcgcaat
    15181 acaagcaatc ggcctcctcc ttatttttcc ggatagcggc agacgctaaa atatccagcg
    15241 tatgaatacc gatcaaagga ataccatacc caaagcataa tcctttagcc acagacaccc
    15301 cgatgcgtaa tcccgtataa gatccgggtc cgctacttac cgccacggca tccagtttca
    15361 tccctttcga cttcgcggcc tctaatgcct cttccatata aacgcccaat aacgccgcat
    15421 gagacggccc ctcaaaggaa gccttctcaa agaccacctc ctccccttcc gacagggcta
    15481 ctgaacatac ggaagtggat gtctcgatat ttaagatcaa tgacataata attaactatt
    15541 aacaattgat aattgaacga acaaacaatc tcaatccttc aatctgatta ggttgcgaag
    15601 gtatacaaaa attcattata ctatcaaggc agccctatga gaaacatcta tttatgagaa
    15661 aataaacatc aaatctaaaa ggaaaccact atctttgcgc aaacttttga gaaaaatgat
    15721 acaatcaatg actgggttcg gtaaggttac tgccgagctc ccttcaaaaa aagtaaccgt
    15781 agagataaag gctttaaaca gtaagcaatt ggatttgtcc acccgtatcc cttccatata
    15841 caaggataag gaaatggagc ttcggagcct gttacttcaa tctttggagc ggggaaaagt
    15901 tgagttcaat atctttatag aatatatagg caaagatact cctacacaga tcaatcttgc
    15961 cgccgtagag aattattaca accaaatcaa ggagatcgca gagaaactga atatcagcgt
    16021 tccgaacgat tggttccaga ccttgctccg gatgccggac gcaatcaagt ccgagaccgt
    16081 agaaccggac gaatccgaat ggggggtggt tttagaaacg gtaaaggacg ctatcaagca
    16141 cctgtgtgat ttccgtatcc aagaaggagc catgcttcaa aagctttttg agcaaaagat
    16201 agccaatatc gccactctgt tgaaagaagt ggagaaatac gagggggaac gtatcgagaa
    16261 aatcaaagct cgtatcatgg ataacctgca aaagatagcc gagaaggact atgacaagaa
    16321 tcgtttcgaa caagaaatga tctattacat cgagaagctg gatgtcaacg aggaaaagaa
    16381 ccgtttggac aaccacttga aatattttat ctcaaccatg gaatccggtc acggccaagg
    16441 caagaagctc ggttttatcg ctcaggaaat ggggcgtgag atcaatacgc tcggatcaaa
    16501 gagcaaccac gccgagatgc agaagatcgt ggtccagatg aaagacgagt tggaacaaat
    16561 caaggaacag gtactaaacg tattataata agattaacga gaatggctgg caaattaatt
    16621 atcttctccg caccctcggg ttccggaaaa tcaaccatta ttaattatct tttgaaacaa
    16681 gatttacacc ttcgtttctc catctcggct accagccggg ctccgcgggg aaccgagaag
    16741 aatggtgtgg aatattattt ccttacgccg gaagagttcc gcagtcgtat cgctaatgga
    16801 gacttcttgg aatatgagga ggtgtatacc gataaatatt acggtacgtt aaagagcgag
    16861 gtagagcgta tcttgaacga aggggataac gtgattttcg atgtggatgt ggtaggcgga
    16921 tgcaatatca agaaattcta tggagaccgt gccctgtctg tctttatcca acctccttgc
    16981 atcgatgacc tacggaagcg attggaagga cggggaacag acagcccgga agttatcgaa
    17041 agccgtatcg ccaaggctga gtatgaatta gggttcacgg gacagtttga taaggttgtc
    17101 gtaaacgatg atctggagac tgcccaaaaa gacgcgttga agatcattcg tgagttctta
    17161 aacaaatagt ctatgtctaa tatattcaag aatacccgtt ttatgatggg gctttctatc
    17221 gtttgtggga tagcgagcct cgtattaggt ggtattagcc tgtattataa ggagtatatc
    17281 atcgggggtg ccctgatatt taatatattc atttgtttca tcaactataa gggttggcaa
    17341 aagaagggct aagtaaaaat cgtatgggac tcaagaccgg gatttacagt ggatcattca
    17401 atcccattca cataggccat ctcgccttgg cgaactggct atgtgagttc gagggattgg
    17461 atgaggtgtg gttcgtagtc acgcctcaca atccgctgaa gaaaaaggat gacctgctcg
    17521 atgactcact acggctggaa atggcccaag ccgctattga cggatgtcct aaattcaggg
    17581 tctgcgatat tgagttctac ctaccgaaac cttcttattc cattgatacc ctacgaacct
    17641 tatcccgtaa ctatccaaat cgggactttt attttatcat gggagccgat aactggcagc
    17701 tttttccccg atggaaagaa cacgaaaaaa tactccaaga ctacaaactg ctgatttatc
    17761 cccgcctagg attcgacatc tcgatccctg ccatttatcc gaacgtgaaa aaggtagacg
    17821 ctcccttgat ggaaatctcc tccacattta tccgtaacgc ttaccaaacc ggcaaggata
    17881 tccgtttctt cctgccggaa ggagtgcggc cttatttcgg gtcagtagca aatcagtgac
    17941 atacctgcga tagaagatat acttacttgg gctatgaagt atatatccta tgccacttga
    18001 agtatatatt cttcgagaag ggaagttata ccgtgattat ttacagcttt gccatcttag
    18061 ggcaatctgc caaaattccc attaaaacat gttttacagc acagccgtta aagatgatcc
    18121 ccgtaacatc aaaacaggct cacccgataa tctttttgga gtatccaaat atataatttg
    18181 agccttgtca agtgaataac taatggctag tcaagtgaat aactaacggt taggggtagc
    18241 cgttagttat tcacttggga agtgattagt tattcatttg ggaggctttg tacctatagc
    18301 ttacgctatt acataaaaca ctattacata acaaattaca tcaatacaat aagtcatttc
    18361 tcgaacaaat taaacgtggg acagaacaat cgaattcaca tagctaactt atatgcatat
    18421 ctccactaat tttctactgt agcaatagaa agacaatata cattaaacaa caataaaaaa
    18481 gacataatat accccatgtt tgatattttt taattttctt tgtaatatca aagtattaca
    18541 catctattaa ctttttaaat ctttcaaatt atggacaaac tcaaaaaaac tgacaaaagt
    18601 cgtactaaac caacaaagta aagttcttcc aaaagaacaa atgatgaaaa tcttaggggg
    18661 aggaagtgcg tattgtcatt gtcataatct ttcttcctca attgaagtaa caagctgctc
    18721 tgaatgcagt aataaatgct caaattatgg cggcgtacaa aactgtaaca ctacaggagg
    18781 ttagcaacaa aagaaagggc tggttttagc tggtgatatc tgctaaaacc agcttttttc
    18841 ttaaaacaaa aatgaccatg atctatcttc tatttttagt cactcttttg cttatcagtt
    18901 gtaatccgga tcaagccaag gataatggca aggacgaaac aatcgagtat tttattccac
    18961 tctcacatcg ggtagaaaaa gacgtggatg aaatgtttga ggaatatcgg tatgtccccc
    19021 ttggaaacaa gggatgacgc attgatagat gtgctttaca atgttaaaaa catcgctatc
    19081 tttcaagagg atatttacat aggctccgga gagcaattaa tcgtttggga taaatatgga
    19141 aaattcaaac gagtcttatc caaaaaggga aatgatccgc aatcatacct ccactttaac
    19201 catttcatga tatggcccaa tggagatcta tcgatcgctt ctcccattga aatcgtaacc
    19261 tattcaaatt cacaccaatt catcaacaaa aagcgttgcg agaatgtcgg ctatatagag
    19321 gcgatcactc ttttgaacga tagtctatac atcataaaat gtatgcctac ccccgaacag
    19381 ctacgatacc gtatcatcaa ccatcatacg ggagccatta taaactcgta tgattccatc
    19441 atcaactgca atcgatatat cagttcattc acaaactcat ttgaacggta tgaaggacat
    19501 attatctctc atggttatca aagcaacgac atccttgaat gcactttgga tagttcaaaa
    19561 atacgataca aaataaacgt agataacagg ataccgcccg ccggctttta cacgcaagag
    19621 ggaaaagaag gcatgcaact catacaggaa gaagcggaga aaggatacat cggccatatc
    19681 ccggactacg tggagtccaa ggaaacgata ttgctctcct ttaaggggaa aagagaagac
    19741 ctaaacggaa tagccttaat cgacaaaaaa gacggaaacg caagagtttt agagaacatc
    19801 aagttcgatg acaacttccg gtggttgccc aaacagttct tctcgttaga tgagggctgg
    19861 tgcgccatgc tgatgtatcc ggaagacgtt ttgaagaagg aagagttcgc aaggcgtttc
    19921 cccggactgg acgaggagag taacccggtg ttgttcattg gtaaactaag gtaatcatta
    19981 aagacctaaa gcaatggaac atgacaatct attcatccaa attttagaaa tcttatcgat
    20041 aaagtacacg gaagatttta ccataagatt ctacgagagc catccacaca aaaacaatct
    20101 gtttggactg tccgagatgc tacgttatta taatatagag aatgtagcgg ccgaaattca
    20161 aaaaacacaa gaaaacttat cctcattaga tgtacccttt gtggcttacg tagatcatga
    20221 gtttgtattg gtgcgacatg tttctaccga ggcaatcatc tattcatggc gaggtaaaaa
    20281 catcacatta tctatcccgg tattcttgga acgatggtca ggaatcgtcc ttcttttcga
    20341 atccaccgat gaatctatta accggattat aaagaacata gaaagaatac ttacgacagc
    20401 ggatagtaat cgtatgtttc gtatcattac ttctatcatt aatagggtgt gcccttatca
    20461 ccaacagagg aatggagata ggaatctggg ggttatgggg tgttaatgtg atcggagcat
    20521 ctttctgcgg tatcctgctt tctcgagaga tcttaggctc ggataaatat gtcaacaaaa
    20581 tttgttccct gtttttgaaa tccagtgatt gcaacgggac attggattcc caagcatctc
    20641 atttcttggg gatcagttgg agtgtcttcg gcttaggata ttttctttcc gcaatattgt
    20701 ttatcgcctt gttgccccaa tatgttatat atgcagagac tctgaatata atcgcattac
    20761 cttatacagc gtggagcgta tggtaccaaa aatttagggt aaaacaatgg tgcgctttat
    20821 gtttatctgt acaagctacc gtatggatca cctttcttat ctctctattc gcgataggca
    20881 tggatttcaa tcaatgggat ttatttgatt tcactaccat tggatgcgtg tatgggctcg
    20941 tcattctatc actccatttt actgttacat tatacgtaaa agaaaagcaa atccaacgaa
    21001 gcaacaataa acttagcagc ataaaactga atgcctctgt atttaagagc ttattaaacg
    21061 aacagcctca atatgacatt gacaaaaata caggaatatt attgggcaat agggatgcca
    21121 aagagtggat taccattatc tctaatccac attgtgctcc ttgcgtaaaa ttacatctcc
    21181 aaatagaaaa gttactcaaa gaatataaag aagagatttg catacaaatc atcttgacct
    21241 cttttagcaa ggaattagaa cctagcgcca tgctactgac ctccatgtat ctactaaata
    21301 atgaatcgga ttatttacga ttcctatctg actggtatgc aaaagggcgt cataaaaaag
    21361 aggattgcta taaaagatac agattaaatc ctaatgacaa agatatgtta gccaattttc
    21421 aagcacaaaa cgaatgggtt aggcgcaata caataagttc cactccaaca gttttgacaa
    21481 atggttattt attgccggaa gaatatgagt taaaggatat gtcgtattta ataaattagc
    21541 atcacaaata gattcgctaa ataagcattt gataggctca ttacatacaa gctacccttt
    21601 cgggttggct catggcaaaa tgggatcact catctattta taccatttgt atgattatac
    21661 gcaagaagct atttataaag agaaggctga gcgattgctg gacgatctct tggaaaacga
    21721 tctctctaaa aacgcagaac tcaccgtgga ggaaggttta tgcggagttg cgttaggatt
    21781 ggattatatt gtaaaaaagc aatttgtaga cggtgatatt aatgatttgc taagtggtat
    21841 cgatgatttg ctattcaaga agctggtttt cggaaatatg gaatctaggt attccctgtc
    21901 tcaactcatc catttcttat attacattta taaaaggctg gaaatccaga caaacgataa
    21961 tgagcgtttc cctttcgagg gcttagcaat caagttagtt aatcaattgg ccgatttgat
    22021 agacgcctcc tttttcgagg aatcctatac gttttccatt taccaatatc acgtaccgat
    22081 attgatgaaa accctgtcct gtcttataca atatgatttt tacaaggatc ggatacaaaa
    22141 ggttttggaa caactatctc tgtatatgtt ctcccatttg cctcatctgc atttgaaccg
    22201 actatatctg ttatggggca tactaccttt acggaattgt tcgccggatt ggcaaagata
    22261 tgtgaacgaa ctaagaaaat caatcaatct agacataata tataatagag agatcaaagg
    22321 caaggatatc tatatcagta atggatacgc ttctctatat ttcttgttgg agggattaaa
    22381 aagggacttc cccgaataca ccatcccttt caatccgcac ctaatttacg atcggatcat
    22441 ctcgtctgac gcttgggatg ccctaatgga gaacgaatac tactataata tacacagagg
    22501 attgctgaat ggtttccccg gtacggtgtt ggcattgtta aacattaagc aaagatattt
    22561 atgcgaatag acttgacaga tacaacattt attattcctg tacggatcga ttccatgatc
    22621 cgtttggaga atctgttgat gtccgtggac tcaatagtac gttatttccg gacacgcatc
    22681 ttaattctgg aggcctcatc ataccaaaat gagattatcc cctcgttaat aaaagatgat
    22741 acggtgaagt acactttcct cgtggataaa gatcctgtat tctacaagac caaatacttg
    22801 aatatcctcg caaagcaggt tgatactcca cttgtttgta tttgggacgc agatgtgata
    22861 ctggaccacc ttcaaatatt ggatgcggtg aaacagctta gaactaggac ttctgatgtc
    22921 gcttatccat atgatggtaa ttttttagat acgtcagata tattgaggga acattattgg
    22981 ctccatcgtg acttagattt cctaaaaaaa catcaagcaa agatgaactc tttgtacaca
    23041 gtagagggag tgataggcgc agtcggggga gcggtcttcg cccaaacgga aaaatacctg
    23101 caagcgggta tggagaatga ggatttctat ggctggggct tggaggacgg agaaagacat
    23161 taccgttggt tgagttttgg ctaccggatt tatcggagtg agggctgttt attccatttg
    23221 tctcatcccc gggatcaaaa cgggatgtaa agataaaatt attgggtctt aagttcattg
    23281 gcctacaaac ctaagatact tcaccaagga tcctaagata ctttatccat gaactaacaa
    23341 gatcggtgac ctcaaccttt taccacataa gtcagcataa atcagaaata ttttgtactt
    23401 ttgcgccgta ttatacaaaa taatagcata atgaatctat tagaactgag tgaacaggaa
    23461 ataataagac gtaatagcat ggaacagttg cgtcagatgg ggatagagcc ttatcccgca
    23521 gctgagtatg taacgaacgc attttccaaa gagataaaag agacattcaa agatgacgct
    23581 gagccacgcc cggtacgtat cgccggccgt atcatgagcc gtcgtatcat gggaaaagcc
    23641 tctttcatgg agttgcagga ttccgagggc agaatacagg tctatatctc tcgtgacgat
    23701 atttgtccgg acgagaataa agacacatac aatgtcgttt tcaagaaatt actggatatc
    23761 ggtgatttcg tcgggatcaa gggattcgtt ttccgtactc agatgggaga gatttccgtt
    23821 catgcgcaag aattgacagt tctgtctaaa tcacttcgtc cgctaccggt cgttaaatat
    23881 aaggatggtg tcgcttacga cggttttaat gacccggagc ttcgttatcg ccagcgttac
    23941 gtggatttgg tagtaaacga gggtgtaaaa gatattttca tgaaacgtgc ggctatcatc
    24001 aagaccatgc gtaccgcctt ggatgaggcc ggatatacgg aggtagagac tccgatcctg
    24061 caatctatcg ccggaggagc tagcgcacgt ccgtttacga cacatcataa ttccttggat
    24121 atcgatttat atttacgtat cgctaccgag ttgtatttga aacgattgat cgtcggtgga
    24181 ttcgagggtg tatacgagat cggtaagaat ttccgtaacg agggtatgga ccgtacgcac
    24241 aacccggagt tcacctgtat ggaactttat gttcaataca aggactataa ctggatgatg
    24301 agcttcaccg agaagctgtt ggagcgtatc tgtatcgccg tgaacggtac gagcgagagc
    24361 acgatcgacg gtaagacaat cagcttcaag gctcctttcc gccgtttgcc gatcttggag
    24421 gcgatcaagg aaaagacggg ttacgacttg gaaggtaaga gcgaggacga gatccgtacg
    24481 atctgcaagg aattgaagat ggagatcgac gatacgatgg gtaaaggt
//
