LOCUS       gnlProkkaCCCDCJJA_52   13797 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CCCDCJJA_52.
ACCESSION   gnlProkkaCCCDCJJA_52
VERSION     gnlProkkaCCCDCJJA_52
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:56:36
            Original ID  :: gnl|Prokka|CCCDCJJA_52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13797
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13797
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3452:3797]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3453..3797
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13797
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13797
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             232..1743
                     /locus_tag="ctg10_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1816..2883
                     /locus_tag="ctg10_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSTEPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSKSSSDKKTAPAPTVLSKIANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTRD
                     KEEKTFTVRLTPDREFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2907..3191
                     /locus_tag="ctg10_3"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLSEGREASRLRRERANDKLKHLNRTNEPYPLP
                     NTTPEEMGRIIHDSEKKKEKDSNYFVWGTLIIMGVLIATAVIFWAIFLN"
     CDS             complement(3453..3797)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_4"
                     /sec_met_domain="PqqD_RRE (E-value: 3.1e-10, bitscore:
                     32.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-17, bitscore: 55.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPAGMSKELHVRLEEHGTAVWELIDGKRTVREIIEELADHFQNEAGYESRVSAYLSQMQ
                     KDGFIKLFIN"
     CDS             complement(3893..5281)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 95.3; E-value: 4.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg10_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGYTDEGGAFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSLMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5529..5924)
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5931..6704)
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6710..7237)
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7224..8465)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 389.3; E-value:
                     4.4e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPVIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQVGTVVTTPVVTTHQPSVPA
                     IIHTMQPAVCKDDDDIQDTEEYVEEPPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8475..9569)
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9574..10614)
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10633..11643)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_12"
                     /sec_met_domain="PF04055 (E-value: 1.3e-17, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
ORIGIN
        1 agaaatcttt ttcagggaga aataaaagta agttcataat ggtgcagcat tgaattattt
       61 tttggcggag ttattctaac acttaatagt tcaaaagcag atatttcttt gaccaaaaga
      121 tagaactaat gatgaattaa aagttgcaat tatggttttc ttcccacaac aaacgggaaa
      181 agtcagaaga atcatgtaca tttgtaatcc gaaaactaaa agaacatcgc aatgaaaata
      241 tttccaagca gcagtatcaa gaaattggac gcttatacca ttgagaacga acctattgca
      301 tcaatcgatc tgatggaacg tgcagcaacc gtattaacaa aagccatcac agacagatgg
      361 aatacggaaa cgccggtcac tatctttgcc ggaccaggga ataatggcgg agacgctctc
      421 gccgtagccc gcatgatggc tgaaaaagga tataaaatcg aggtatttct cttcaacacg
      481 aaaggagaac tttcacccga ctgccagacc aataaagaac tggtagaaat gatggaagaa
      541 gtaaaattcc acgaaatcag tacccaattc gtacctcccg tcctgacgcc cgatcatctg
      601 gtaatcgacg gattattcgg ttcaggtctg aacaaaccgt tgagcggtgg attcgctgcc
      661 gtagtgaaat acatcaattc ctcccctgcc atggtagtag ccatcgacat tccttccgga
      721 ctgatgggag aagaaaatac attcaacgta aaagctaata ttatccgcgc cgacgtaact
      781 ttcagtctgc aactgccgaa gctcgccttt cttttcgcag agaacactga atttgtcgga
      841 gaatgggaag tgctggatat ccaattaagc gaagacggta ttgaagagat ggagactaac
      901 tacgaaatgt tggaaataga agaaatccgt tcactcatca agccacgcaa acagtttgcc
      961 cacaagggga acttcggcca tgcactattg attgccggtt caaaaggaat ggcaggagcc
     1021 tctgttctcg ctgcccgcgc ctgcctccgt tcgggagtag ggttgctgac tgttcatgca
     1081 ccaatgtgca acaacgacat cttgcagacc tccatacccg aagcaatcgt agaaaccgac
     1141 atcaacgaaa cctgttttgc cgtacctacc gatacggacg actaccaagc agtcggcatc
     1201 ggcccgggac tgggacgaaa cgaggaaacg gaagctgcct tgttggagca actggaacac
     1261 tgccagactc ctgttgtagt ggatgccgac gctcttaata tcctcgccaa ccaccgccat
     1321 acccttaccc acctgccgaa gggttccatc ctcaccccgc atccgaaaga actggaacgt
     1381 ctgaccggca aatgccagga ctcttacgaa cgtctgatga aggcttgcga actggcccgt
     1441 gccgcccatg tccacattat tttaaaagga gcctactccg ccatcatcac ccccgaaggt
     1501 aaatgtttct tcaacccaac cggaaatccg ggaatggcaa ccggaggtag cggtgacgta
     1561 ctgaccggag taatcctggc gctgcttgcc caaggttatc ccaccgaaga agccgctaaa
     1621 atcggcactt acattcacgg attggcgggc gatgtcgctc aaaagaagca aggaatgatc
     1681 ggaatgatcg caagcgatat tatcacctgt ctgccgacag catggcgact tgtaagcgaa
     1741 taaaagttaa gaacttacag ttttttcaat aacttcatta actttgtttt caaaaccagt
     1801 taaaaagaac cgaatatgaa aaagttgatt atagcagcag gactacttat gacaacgtcc
     1861 gcctatgcac aaaccgaagt actgacaggg gttacccggg gaaaagatta cggagtagtc
     1921 tacagtcttc ccaaaaccca aatagagctt gaaataaaag ccaacaaagt caactatact
     1981 ccaggagaat tcagcaaata cgctgatcgt tacctgcgat tgaccaacgt ctccaccgaa
     2041 cccgaagagt attgggaact ggctagtgtg aaggtgaaat ccgtaggtgt acccaacagc
     2101 gaaactactt acttcgtaaa attgaaggat aaaacagtag caccactcat ggaactgaca
     2161 gaggacggca tcgtgaaaac catcaatgtg ccttacagta aaagcagttc agacaagaaa
     2221 acagctcctg ctcccactgt cctctcaaaa atagcgaatc cccgcgaatt cctgaccgaa
     2281 gaaattctga tggccagctc taccgcgaag atggctgaac tggtggctaa agagatctat
     2341 aacatccgcg aaagcaagaa tgccttattg cgcggacaag ctgacaatat gccttcagac
     2401 ggagcacagc ttaaaattat gcttgataat ctgaatgcac aggaagaagc aatgacgcaa
     2461 atgttctccg gcactcgtga taaggaagag aagacattca ccgtccgcct tactccggac
     2521 agggaattca acaacgaagt tgctttccgc ttctccaaga aactgggtgt agttgccaac
     2581 aatgatctag caggaactcc gttttatatc agcttgaaag acctgaaatc agtcaagatc
     2641 ccacaggaag acggtaagaa gaagaaagat ttggatggaa tcgcctacaa cgtgcccgga
     2701 caagcaatgg ttacattgac cgacggtaaa aagaaacttt acgaaggtga actccctatt
     2761 actcaattcg gtgtgataga atatctggct cctgtcttat tcaataagaa ttctacaatc
     2821 aaagtttatt ttgatccgaa tacgggagga ttgttaaaag tggatagaga agaaggcaaa
     2881 tagtaaactt ctaaagggca aagaatatgg gtggtgaagg acacatgctc gacatgatac
     2941 gtcggcttag cgaagggcga gaggcttccc gtctacgccg tgaacgtgcc aacgacaaac
     3001 tgaagcactt aaaccgcacc aacgagcctt atccactgcc caacaccact cccgaggaaa
     3061 tgggacgtat catccacgac tcggagaaaa agaaagaaaa ggacagcaat tatttcgttt
     3121 gggggacgct tattatcatg ggagtcctca ttgcaactgc cgtgatattc tgggctattt
     3181 tccttaatta gataatttat tagatgatag ttgataaatg atagatggga gatgcttcct
     3241 aaatgataag ggatattcag taaataagaa atataagtaa ctaaagatat tctcaaaata
     3301 ctaaaaaggt aactacatca ttacgaatca gttgcctttt ttcatatctt taaacgggat
     3361 atttgataaa cctccttagg aggctgcact atcatataac tagctattat gccgcatagt
     3421 aactatcatt tatcacctat catctaataa agtcaattaa taaaaagttt tataaaccca
     3481 tctttctgca tttgagaaag ataagccgat acacgagact cgtatcccgc ttcattttga
     3541 aaatgatctg cgagttcttc tatgatttca cgaacagtac gttttccatc tatcagttcc
     3601 catacagccg taccgtgttc ttccaatcgc acatgaagtt ctttcgacat tcctgccggt
     3661 acaaggaagc gttgcatcca cggatattta aaacggggaa aggagagcac aatcgtctcc
     3721 ccttcccttt ctgctgtaat atgttcactg cgacagggaa tgacctctaa caggttgatt
     3781 ttctctttgg cagccataat tctttttttt atttcagagc attaatacta accctctttt
     3841 attttcaaac cttatactct cgaatttata acgttacttc gaattgtaac tgttacttct
     3901 ggatatttgc ctcttccaaa ccatatcctt tcttcttgtt ctctgctttc aacatcaaag
     3961 caacaatcag agcaagtaca ccaaagagag caaaaatagt catcggcaat gtgtaatcat
     4021 aagtctgtgc accgtctacc accggacctt tgcaataagt attcaatacc catccgatta
     4081 acaaaggaac acccatcagg ccccagttct gtacccagaa aatcaaagcg taagcagtac
     4141 ccagctgttt ttccggaata atcttcggaa cagaaggcca catagccgaa ggcaccaatg
     4201 agaaagcaaa tcccaatata atcattataa tagtagcaaa ccaccatata ttcagtatag
     4261 gcagggcaaa catggtatgt acaaaaatta gcatcaatga tccgatcacc atcaatgtgg
     4321 ctcctttacc gatacggtca tataacgaac cgaacaacgg agtcaggata attgcaccaa
     4381 tcggcaacaa tccgggaatc gttcccgcca gtttcggatc tacattatat ttctgcacca
     4441 tcaagtcggc agcatatttg ataaaaggga agacggccga gtagaacaat acgcacagca
     4501 atgcgatcaa ccagaatccc ttattggtaa tgatatacac aatatctttc atacggaacg
     4561 gttcttccgg ttccaaacct tctgcatcca aagaagcatc caatttctta tcatagaaag
     4621 tataaaggaa gaaagcaatc gtacccacgc acaacataat cagacaaaac aaaataggag
     4681 caggaatatt ggtatggaat gcaccaccct cgtccgtata tccgaagaag tctgccaaag
     4741 gaactgtcaa caccatcgcc agagttgtcc caatacgtgc cgtagccatt tcaagtccca
     4801 tagccaatgc catttccttg cccttgaacc atttcactat aatcttggaa acagtgatac
     4861 cagcaatctc cacacctaca ccaaagatag catatcccaa tgcagccaac gtcacctgtg
     4921 ttttgaatcc gaagagcatg gcaccttccg gaaaagtagt agaaatcgca tagtatttca
     4981 atccacaacc aaacaccatc aataagcaag ctcccattcc ggtgaaacga actcccattt
     5041 tgtccaaaat gataccaccg aagatcagca tcaataggaa tacattaaac cacccgtaag
     5101 cgcttgtgaa gaaaccataa tcaagactat cccatagtag ttctttctca agcatgggtt
     5161 ttagaggaga cattacgtcg gtgaggaaat agccgcatag catagtaaat gcgaccaatg
     5221 ctagaacact ccatcggagt acggcggagt cattcaattt ctgtttcaaa tgttctgtca
     5281 ttgttatatt taaaaaagta gttaataatc ttatacagcc aacaaaggta gttaaatctc
     5341 gtttgtttct atcacaaaga gattgttttt acaagaaaaa gttaagtgcg gattacactg
     5401 accacgcgga acattgaaaa tccgtgtaat ctgcgtaatc cgcacttaaa tatcaaagaa
     5461 atgcagcatc cgtctgcacc ttcccattaa tggttttacc ccaaagtctt acctgacgac
     5521 ggagtgaatt actctgctgc aggagcagga gtttcagtag ccggtgccgg agtttctgta
     5581 gcaggtgcat tggtagcagg agcttcagtt tgcggcgcag ccgtacctgc gggtaagtta
     5641 tacgggttag tctgttgttc tttctgtgcc tgttccaaca ctgcgtcttt agcaacagca
     5701 gagcgaggaa ctacataagc agtagcaatg ctcattacaa ccataaagat ggccaggccc
     5761 catgttgctt tttccagaaa gtctgtagtc ttgcgcacgc ccatgatggc gttagatgaa
     5821 gagaaaccag aagcaagtcc gcctcctttt gagttctgaa tcagcacgat gaaacacatc
     5881 aacaaggctg caataaccat taagataacg aataataagt acatttttag ttattttgaa
     5941 ttagcgttaa taatcaattt ctccaaaaat ctgatttggt ctgcaaagta agcatttttt
     6001 tttggatatt tcaagcttaa ttttttaatt atttcaagag cttttgaata tcgttgctgt
     6061 ttaacataga tttttgccaa agtttccgta aaacagctgt catcttcctc ttcttccttc
     6121 atcgtttctt cttcggtaag ttcgtccgaa gaggttggcg aagatggcat ttcttctctt
     6181 aaaggtttca tgcagagggg agagtcgctc tcgctctttt ctataaagtc gtcaatcagt
     6241 tcgaagcctt tgagtttggg cgtttcttca gccggctgtt ccgtggccgg agtctcctcc
     6301 aaaaggaaag aggtgtaatc catcgaatag tcgaaactgg tccgggcagt cacctcttcg
     6361 ggtactgtgg acaagaaagc gtcgatcaat gctaatgtgc ggtctacgga cggttcgtct
     6421 ttcagcacct ccgtgagagg tactcccttt ttccgtgcct gcacatcata gcggtcacct
     6481 tcaatcaacc ggaacaactg ccgtctgtct gcaatgtaaa gaactgcttt ccgcagttct
     6541 ccaccgaaac taatatcatg gagaatatac agattcttca gatacagcag acgaagtgac
     6601 tgaaaatacg gatacctcgc aagaagattg cgcagttcgt acaaagtatc cctattcagc
     6661 gtctcgggat gctgaatcca ttgttgaaag ttaacagaag tcatttatat taccagtttg
     6721 ctacagttgc attaaaaatt tgatcggtga tctctttaga catttcagca atcaatccgt
     6781 cctgtacggc agtcaacaac tgggtagagt cgtaggtacg gaacgcagaa aactgttgtt
     6841 caaagtcttc ggcatgattg gtgttgttga caaaacgcac attgacggtg atagtcaact
     6901 tcgtctccga agaataaccg tcggcagata ctgcctgatt gtactgattg taccctgtga
     6961 tttctccgtc aatctgcaag tcggcattct gattcggctt gagcagttgc agacgggtct
     7021 gccgaatgaa gatatctttc aggtcctcat tgaatttggt tgccaacgga gcatatacat
     7081 actccgactt gatcgggaag tcggctatcg aaatggtctt taccttatca taattgatag
     7141 acgatccgtt aaacttatag gaaacagtgc acgcaatgac taccaacggc aagccgaaca
     7201 gtagcaaagg gcgtattatt ttcttaatcc aattcatatt cttttatttt tctataaagt
     7261 gtacgctcgg aaatattcaa gtccttggcc gcactcttcc gctttccgtg atgcctttca
     7321 agtgctttgc gtatcatttc tttttccact tcgtccagtg acaaaggagg ttcttctaca
     7381 tattcttccg tgtcttgtat gtcatcgtca tccttgcaaa ccgcaggctg catggtatga
     7441 atgatcgcag gtaccgaagg ctggtgtgtc gtcactaccg gagtagtaac caccgttccc
     7501 acttgtccta cctgccccac ctgtccggca cgttccgcca tcaggttgtg caccatcttc
     7561 ttcagctccg ccacttcctg gcgcatatca aacagaacag aataaagaat ctcccgttcg
     7621 ctctcaaagc ttttactctc acgcgttccc atcagcgcgg gaagacgttg cgtattttgt
     7681 gcgggaagat aattctgcaa gatagcagca gaaatctccc tgttggtttc aatgatagat
     7741 atttgctcgg tgatgttctt caactgacgc acgtttccgg gccacgggta agccaacaac
     7801 tctttcttcg catcctccgt caactgaata acaggcatcc ggtatttctc tgcaaagtct
     7861 gcggaaaact tacggaacaa caaaagtaca tcgtcaccac gttcacgcaa aggcggtatc
     7921 tggataggca ccgtattcaa ccggtaatat aaatcttcac ggaaacgtcc ttctgcaatc
     7981 gcttgcgtca gattgacgtt tgtagctgcc accacacgca catccgtttt ttgtactttg
     8041 gacgaaccta ctttcataaa ctcgccactc tccagtacac ggagcaaacg tgcctgggta
     8101 gacatcggca actcccctac ttcatcaagg aaaatagtac caccgtcggc ttcgccaaag
     8161 taccctttcc gttcgccaat cgcaccggta aacgcaccct tctcatgccc gaacagttcg
     8221 gaatcaatcg tgccctccgg aatagcacca cagttgacag caatatactg tccgtgcttc
     8281 ctccggctat attgatgaat aatctgcgga aaactttctt ttccgactcc actttctccg
     8341 gtaatcagca cagacaaatc ggtaggagct acctgaatgg caacatctat ggcgcgcgac
     8401 aatgcttcag tatttccaat aataccgaaa cgctgtttca cttgttgtat ctctgctctc
     8461 gtcatcactc gtttttaatc ttcgtctact gtatccagct tcagtttatc actatcgtca
     8521 cgtttctcgt aatactgttt acgcaacgga ttggcacgag ccactttttc ccgctgacga
     8581 ttacggaaca catcgatggc aacatagatt gcctgacgga aagaatcttc acaagccaat
     8641 cccttgcctg caatatcgta tgccgttcca tgagccggag aagtacgtac taccggcagg
     8701 cctgccgtat agttcacccc gtcttccata gccaaggcct tgaacggagc cagcccctga
     8761 tcgtgataca tcgccaggat accgtcaaaa tgagtataat tgcccgaacc cataaagccg
     8821 tcggccgcat aaggaccgta gcaaaggatt cctttctctt ccatttcttt catggcaggg
     8881 ataatcactt cctgctcttc cattcccaac aaaccaccgt ctccggcatg aggattgaga
     8941 gagagcaccg caatacgcgg agcgccgata ccgaaatcct gtttcagaca acgatggaat
     9001 atcatcagtt tctcctgaat cagttctttg gtaatcgtag tcgcgatctc tctgacaggg
     9061 atatgtgtcg tcaccaaagc cacccggaag tcattcttca tcaaaatcat caatgactta
     9121 tcaccattgc ccagacgttc ttcgatatat tccgtatgtc cggggaagga gaactcttcc
     9181 gactgaatcg tatgtttgtt gatcggagct gttacgataa catctatcaa cccttcgcga
     9241 tattcttcga tggcacgttc caaagccccc agcgcagctt taccggcttc gggatcgggt
     9301 ttggaaaatt ccactttcac ctcatcatcc gtacagttca ccacgctcaa acggttgtac
     9361 cccgcttcgg tagcagagtt gacaatgctg aaattggtct gtatatccag cgctttgcga
     9421 tgataagccg ctactttcgg tgagccataa ataatcggag tacatagttc caacatcgta
     9481 gggtcggaaa atgtcttaag aatcacctca tagcccaccc cgttaatatc tccttgggtg
     9541 atacctatcc ttatcttgtt atcttccatg tttttattta ttagtttgtt ccgcttcctt
     9601 agatgcttct cccaatggaa tctgcttctg ctgaacttca ttcggaagtt tcagtgtata
     9661 cagagatgct tccatctggc gtaccaggtt gcgtttcatt ttatcaggtg aataaacaaa
     9721 tatttctgct gtaataattc gttggttttt ctcgtccaga cgagtatgag acacatacgg
     9781 accacccata aagtcgccct tcatacgcca caggccacgt gcttccattg tgtagctgtt
     9841 ctgtacattg atcggacgga catcggtcag caaactatcg gtcgacatat aaacgccttc
     9901 cttgaatccg gggatattgg ctttcatcac ggagtcacgt ttgtgcacaa aatattcttt
     9961 ggtaaacgta tccttgtcag tgtacggata agagtacatc acaaagttac ggtcggcagt
    10021 acctgtgttg gtagaagccc agaagaaatc atccccggtc tttgaattag ccagttcggc
    10081 atccacccag atgtcgcatc cgaacaaact gtccactttc tgcgaaatga aattactgtg
    10141 tttcccttcc aggaacgtaa tctgacggtt catttccgca cgggtaaaga agtcgacaat
    10201 cgtctttttg ttctcttcca caaacttctc gaactcttct tcgttcggag cctggatagt
    10261 caatatcatc tgcggattgg catatacgtc cttcgcatat ttgaacgagg ctttcgtata
    10321 tatatcctgt atatctacaa taataatgtt acgtatcaac ttcagcgtag aatcataatc
    10381 tttcggcgaa gtatacataa tccggaaaga aggttccgac tgcggcaaac cgggcatatc
    10441 agcatcgagc gcatcatgta aagcccttcc ggcagcacga tcccaaacac cgtgatctac
    10501 tacaaccaaa agctcgtaag cacgaccact agaggtgtga tttcctttca gaccacaaga
    10561 tgcaacgaca aaggctacca aagcgatgca taaaataaaa gaatactttt tcatgatgtt
    10621 cggttttata tattaacttt cattattttt ctcctgtttc gctgtcgaca gcataccgca
    10681 agcggcaaaa atatcttcgc ccctggatga acggatagtg gtgaaaagtc cgtgtgatgt
    10741 cagataatca cgaaaacggg tcatcgtatc catatccgcc ccctcgaggt ctacccccgg
    10801 tatggcatga aaacgaatca gattcaccct gcaatccagc ccgcgaagaa gtttcagcaa
    10861 ctctttggca tagacctgcg aatcattgag ccctttaaaa acaatatatt caaacgaaag
    10921 tcgacgttgt ttactaaaat catagttttt taacagttcc accatttcgg tgattgaaaa
    10981 cgccttttcc gccggcatta attcagcacg ctgaacggtc agcggagagt gaaggctgat
    11041 ggcaaggtgg cagtcatttt cttcgataaa acgctgcaat cctttccgta acccgacagt
    11101 agaaagcgtg atacgcttcg gactccatgc gtaaccgtag gtagcggtca gtagttccaa
    11161 tgctttcaat acctcatcca ggttatcgag cggctcgccc attcccatca ttacgacatt
    11221 agtcagtttg tcccgttccg gcagcgaatg aatctggttt atgatctggc tggcggtcag
    11281 gttagccgta tacccctgtt taccggtcat acagaactta cagttcatct tgcaacctac
    11341 ttgtgacgac acgcacaacg ttgcccggtc atcatccggt atataaaccg actctacaaa
    11401 atggttctca cccactttat aaagatactt caccgtacca tctacagagc gcatttcatc
    11461 taccggagct tccgctccca cctcatagtt ctgcttgagc aactcccggt gtttcaatga
    11521 caaattagtc atatcatcaa tcgaggctac cttcttttcg taaagccagg atgcaatctg
    11581 cttggcagca aagccgggca tacccagtct ttttgtcaat gattgaagct ctacaagagt
    11641 cattcctaaa aggggatatt tagacattct tctttctgtt gatagtttat atctgcaaat
    11701 gtaaggaaat aaagtcgatt tccgtatagc aggaatgtaa aagttaacaa aaaagggaag
    11761 tatgcctccg ttatgattca accacgctga tatattgaag tagcttttgc gccatttcag
    11821 aatcctcgcc attctttttc acttcatgac cgtacgcctc acggaaacaa gccagcgcct
    11881 cttcccgttc attacaaaag ctgtgcaaaa cccctaagtt ctgacaagcc agaatcgtat
    11941 cttcttcctc ccatcccaaa tacttctttc gcagttcgaa ctctctgaag aaagcctctt
    12001 tcgccattgg ataattctcc aacttcacat aagcctgtgc tttgtaataa tataccagac
    12061 aggaagcatt agggtcagta tcatcgtgaa aatccaaaga cgttgcaata cgaatcacgt
    12121 tatcatagtc tttattcatg taatactgct gcataatatc acatctcaat gcttcatagc
    12181 ggacagtcag ttccgccaga cgcggttttt cgctgaaata catttcatgc agaagagact
    12241 cacggaagaa taaagtagat gcctgctcat cgccacgttc attcatcatc cgtttgaatt
    12301 ccctgcacag ataatacaac tgtttatgac aagcgacgat ctgttttttg ctatctatct
    12361 gtatagcaat gtccaacgcc tgattcatca gcatccatgc ttcatcgtat cgtttgatat
    12421 aataaagaca tttaccctgc atacgcaaac atttagccac tccaccggac agtctgccat
    12481 tcaatgactc gtgcatttca gctactttcc ggaatttctc ggcagcactc tcttcctcat
    12541 ccttatagta atcacaataa gccagatatt cggaaagttc aatgacttct gcctgactct
    12601 tctcgtcagc agaagccgca tgataatcaa gcgccctatt caaatagatc gccgcttcat
    12661 tgtattgctc attgtagtaa tatgccaaag ctagatttcg acaggtgttg gcaatctcca
    12721 gttccggagt cggtactatg ttttcctgca tcaccaatgc tttcaggaaa cagtcgcatg
    12781 ccgtttcgta ttcttcatta cgggcatacc gacatccctc attcatcttc aataccgact
    12841 tggcaatgag tggcatggca gcaccttcca tactcttctc actcacagca gctgccgcct
    12901 tcgtcagatg gaaagaactg ctcaagaaag tagccatatc attagcaatg acaggaatta
    12961 aaaaagaatc gatctcatca aagtccaatt cggcatagac ttcaggcgta acttcaggat
    13021 tgtcgttcat gatcgccttc cagctatctt ccaacagaga acgattcgta cgatacagaa
    13081 tctcgaaaat ctccacatca caaatccaat ccttcaatat atcccattct tgcatcttat
    13141 agcattgata ggtaatctcc actttatagc gatacgaatc atggtagcag aactgtttca
    13201 tgcgatagtt ataatcggca aaagtcaacg gatgggaaag gatctcttcc tcatccagca
    13261 gagcggaaat aatttcatgg cgactatcat ctatacattc gtcatcttga gcgaaatagc
    13321 gttcgatcgc ctctaccatt tgtgtatcac caatgcaata tcgtcctcct ttgttggtga
    13381 gccagctgct catttccact ctcaactgcg accaaagtat ctgattaatg tctgccatgc
    13441 tcttcacttc atcttcggta aatccttcta aagtaagtga aagcatcaga agcgttcttc
    13501 caatctcttc ggaaccataa tcagccgaca aacgccgtag cacactgtca tagaattgcc
    13561 caacctcatt gagccggcaa tatccacgca tatattcatt gagagcatcg tactgaccga
    13621 acgaaaccag ctcgttgagc aatacactta aacagcgcgg ttgtttagcc agcacccacg
    13681 aagcaagaat atcttcctgc tgtgcagaca aagccttgga gtaagtagac aaatattgct
    13741 ttgagaacga cttggcatcc gcctgtgaaa agccattcaa ctggaaatga gcgtagc
//
