LOCUS       gnlProkkaJFPAIJLH_20   10551 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JFPAIJLH_20.
ACCESSION   gnlProkkaJFPAIJLH_20
VERSION     gnlProkkaJFPAIJLH_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 05:19:14
            Original ID  :: gnl|Prokka|JFPAIJLH_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10551
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10551
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1237:5551]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1238..5551
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10551
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10551
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             26..1174
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSASKKDDKMTLESYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTIPAGGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             1238..1957
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.3e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.8e-17, bitscore:
                     52.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             1978..3279
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 209;
                     E-value: 1.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.7e-122, bitscore:
                     395.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-63, bitscore:
                     204.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             3296..4420
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 61.4;
                     E-value: 1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.7e-20, bitscore:
                     63.3, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.9e-21, bitscore:
                     65.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKTMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIARGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4430..5551
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 4.8e-34.
                     Score: 109.7. Matches aSDomain:
                     nrpspksdomains_ctg20_5_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.5; E-value:
                     3.1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_5"
                     /sec_met_domain="Aminotran_5 (E-value: 3.4e-31, bitscore:
                     98.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGSLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKVSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4520..5527
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_5_Aminotran_5.1"
                     /evalue="4.80E-34"
                     /label="ctg20_5_Aminotran_5.1"
                     /locus_tag="ctg20_5"
                     /protein_end="366"
                     /protein_start="30"
                     /score="109.7"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGSLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKVSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5548..5682
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MIAEILLKIRLFYFSLRGIHFHSESVISGVPIRSFRLVGKYSNI"
     CDS             5895..7379
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_7"
                     /sec_met_domain="Polysacc_synt (E-value: 1.6e-32, bitscore:
                     103.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSAPLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSNNSKDN"
     CDS             7333..8592
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="MKILKKIFLIIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVVKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEYRRHISLLM
                     NKFQDDNSTERICDIFLNEI"
     CDS             8601..9350
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             9350..10390
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEGLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKENVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ttgataaaga aataaatgac ctattatgat tgaaaagcaa tcttatcaag aaccgttttc
       61 tgaagtggat aaaaggaaag atgatgaaat ggaaatagac ttgatggcta ttttttataa
      121 gattattact gttcgtggag tactatgcaa agctgctgga gtgggagtaa taattgctat
      181 agtggtggca ttgagcattc ccaagcaata tacagtaaag gttacccttt ctcctgaaat
      241 gggtaatgcg aagggaagta atggtttagc cggacttgct gcctcgtttt taggagatgg
      301 ggctctaata ggggaaagca cagatgcctt gaacgcttct ctttcagcag atattgtttc
      361 ttcaactcct tttttattgg aacttttaga aatggaagtc tccgcttcta aaaaggatga
      421 taaaatgact ttggagtctt atctcgatga agagtcatct ccttggtggg attatcttat
      481 aggttttccg ggcatagtaa tagggggagt taaatcatta ttcggagaag atacgattcc
      541 tgctggtgga gggcggcaag gaactatcga attgacgaaa gaagtaaatg agaagattaa
      601 ttttcttaaa aagaagatta gtgcatccat tgataagaaa accgccataa cgagcattac
      661 tgtcacctta caaaatccgc aaatcactgc ggttatagca gattctgtcg ttcataaatt
      721 acaggaatat attattgggt atcgaacttc aaaagtaaaa gaagactgtg cgtatttgga
      781 acggttgttt aaagaacgtc agcaggaata ttatgctgct caaagaaaat atgcggatta
      841 tgtagacgcc catgataatg tggttcttca aagtgtacgt gctgagcagg agcgtttaca
      901 gaacgacatg agtttggctt atcagatata tagtcaggtt gctaatcagt tgcaggtatc
      961 tagagccaaa gtacaggagg aaaagccagt ctttgcagta gttgagcctg ccgttgtacc
     1021 tttgaaacct tcaggtatgg gactcaaaat ttatatttta ttatttgtgt tcctgtccgt
     1081 atctggtact ctcgtgtggg tgctttttgg caaaagtctg ctggctagct tgagaaaaga
     1141 actgaaaaat aaggagatag aacaggataa atgatgctaa aacgtcgttt acaacattct
     1201 tacatcaatt aaattcactt actatattat taaacgaatg atacgtacag ctatgataat
     1261 ggctgcgggc atgggaaccc gttttggcca atatacagaa ttgataccta aagggttcgt
     1321 caaagtggga ggtattccaa tgatagttcg ttctattgat actttgttat catgtggcat
     1381 tgagcgaatt gtaatcggta caggatataa acaagaagtt tatgaagaat tgaagacaga
     1441 ttatcctatg cttgaaacct gttttagtcc tcgttatgct gaaacaaata gtatgtatac
     1501 tttatataat acgcgggaga ttctgggcaa tgatgatttt ttattgttag agtcagattt
     1561 gatttttgag aaacaagcaa taatgagctt attggagtgt cctgcggcag atgcgatgct
     1621 aataactcca gtgacaaagt ttcaagatca gtattatgtg gaacatgatg ataattttcg
     1681 cctttcttca tgttctgtca ataagaataa actaaacgct aaaggcgaat tggtcggcat
     1741 ccataaacta tccggttcct tttacaaaat aatgtgtgct gattatgcga gtattgttga
     1801 tgaacaaccc aatttgggat atgagtatga attactacga atatcttgtt ctcaatctcc
     1861 tgtttatgtg cataaagtag aagggctgaa atggtatgaa atcgatgaca tatcagattt
     1921 ggaatatgca gagaaatata ttgttccgta ttgttaatta aaataatata tcaaattatg
     1981 agtaagacag tttatattgg gatgactgcg gatattatgc atccaggact tatccgcatt
     2041 attaatgaag ctactaaata cggtgatgtt ataattggtc ttcttacaga taaagctatt
     2101 gcggagcata aacgccttcc ttatctgacc tatgaacaac gaaaagaggt agttcagaat
     2161 attaaaggcg tatgtaaagt tgttcctcaa gaagaatgga gctatgttga gaatctcaaa
     2221 cgcattaaac ctgactatat aattcatggt gacgactgga aaaccgggcc tttacgtgaa
     2281 gaacgtgtgc gcgtatttga agtgatgaat gaacagggag gaaaggttat cgaaattcca
     2341 tatactttgg gaattaattc atcttctttg gataaagata ttaaggctat aggtacaacc
     2401 cctgatgtac gtttaaaatc acttcgtcgt ttgataaatg ccaaacccgt agttcgtatt
     2461 ttggaagctc atgatggact atgtggcttg ataattgaaa atcaggaaat attaaaaggg
     2521 gataagaggg aagtatttga cggaatgtgg tctagtagcc ttacggattc aaccagtaaa
     2581 ggtaaacctg atattgaggc agttgattta actacccgat tgcaagattt gaataatatt
     2641 ttggagtgta ctactaaacc tattattttt gatggagata caggtggtaa aattgaacat
     2701 ttcgtattta cagtacgcac tttagaacgt catggaattt cagctataat aattgaagat
     2761 aaagttggat taaaaaagaa ttcattgttt ggtacagatg ttattcaaac tcaagataca
     2821 atcgaaggtt tctgcaataa gatcaaagcg ggaaaggcat ctcagattac tgatgatttt
     2881 atgattatcg ctcgtattga gagccttata gcgggaaagc cggtaagtga tgctttagag
     2941 agagcttttg catatgtcca agcgggagcg gacggtatta tgatacatag caaaaataag
     3001 tcgggtgaag atataaaaga attttgtttg gcatttcgaa aacagtatgc tcatgtacct
     3061 attgtggttg tgcctactac atatgatcat atttatgagt ctgaattgtg tgattggggt
     3121 gtgaatataa ttatttatgc taatcatatg cttcgtgccg cttatcctgc tatgatgaat
     3181 gtcgcaaaga caatattaga gaatgaacgt gctttagagg tgcgcgaact gtgtatgccc
     3241 ataaaagaaa tattggaact gattccaggt actaaataaa aagaggaata tcattatgtt
     3301 aagcgtagaa aaagtttatg aaacgtttct gagtcatgat gttgattttt ttacaggagt
     3361 tccagactca ttactaaaga atatttgtgc ctatatcaca gaccatactt cacgtgagaa
     3421 acatatcata gctgctaatg aaggtgcggc tgtaggaatt gcttcaggtt attatatggc
     3481 atcaggtaag gttcctgtgg tttatatgca aaattccggc ttgggtaata ctgttaatcc
     3541 tctgctgtct cttgcagatg aacaagtata cagttttcca atgcttttga tgattggctg
     3601 gcgtggtgaa ccgggaacaa aagatgaacc tcagcataaa aaacagggtg aggtaacttt
     3661 agatttgttg aaaacaatgc ggattcctta tataattctt gattcaaatg agaatgatgc
     3721 atttattcag ctccatgata tcatacaatc agcaaaaact aagaatattc ctcatgcaat
     3781 aattattcgg aaagatgttt ttggcaaata taaacttcaa aaagaatttg gatgtaatta
     3841 tcctttgtct cgtgaggatg ctttgcaaat agttgtggat tatctgcctg aaaattcagt
     3901 ggtcgtttct actactggca agctttctcg tgagttattt gaatatcgag aaatgaaaga
     3961 gcaaggacat gaacatgatt ttctcacggt aggctctatg ggacatagtt catcaatctc
     4021 tttgggtatt gctatagcaa agcaagatag acctgtttat tgcttggatg gtgatggagc
     4081 atttattatg catttagggg caattagtaa cattggcgat ttatctccta aaaactatta
     4141 tcatattttg tttaacaatg gtgctcacga gtctgtagga ggacagccta ctttaggatt
     4201 tagtttagat attccggcta ttgcccgggg gagcggatat aagcatactt atactgtttg
     4261 tacaaaagtt gaaattgaag aagcaatgaa gcagcttcca aagttatgtg gtcctgtttt
     4321 gttggaaata aaggttaaga tagattctcg ggagaatttg ggacgtccca cgactactcc
     4381 tatagagaat aaggagcatt ttatggattt tttaaaataa atatattcga tgaaaataga
     4441 aagaaaaata ttattaaatc ctggccctgc cactactact gacagtgtaa aaatggcaca
     4501 agttgttccg gatatttgtc ctcgcgagaa agaatttgca ggtatgatga aacaacttcg
     4561 ggacgatttg gtcagagttg ctcatgggag tttggaaaaa catacagctg tattattttg
     4621 tggctcagga accatcaata ttgatatatg tctaaattct cttcttcctg aagacaaaag
     4681 ggtgcttata gtgaataatg gggcatatag tacccgtgct gtagaagtgt gtcaatatta
     4741 tggtttgcct catattaatt tggaattttc tgtttatgaa cgtcctgatt tatcggtagt
     4801 ggaaaatgtg ttacaagaaa atcctgatat agctatggtt tatactactc atcacgagac
     4861 gggtacagga attctgaacc ctattcgcga gatgggcgct atagctcata aatatcaggc
     4921 taaatttgtc gtcgatacta cttcttcttt gggcatgatt ccttttgata tagagaaaga
     4981 taatgtagat ttttgtatgg catctgctca aaaaggactt caagcgatga caggtctttc
     5041 ttttattata ggcaatgagg aacagattaa ggtttcaaaa aaatatccca agcgttctta
     5101 ctattgtaat ctttatttgc agtatgagaa ttttgagaga acaggtgaaa tgcattttac
     5161 tccaccggta caaactattt acgccactcg tcaggcatta aatgaatatt ttgaagtggg
     5221 cgaagaagct aagtttgccc gtcacaaaag agtttttgag gctattcatt caggtataaa
     5281 tgaaattggt cttaaaagtg taataaagcg tgaatggcag tcaggactgg ttgtctcagt
     5341 tcaataccca gaagatccca actgggattt tgagaaaata catgattatt gttatgagcg
     5401 tggatttacg atttatccag gtaagatatc aactgaggat acttttagaa tctgtgcttt
     5461 aggagagata gaagtagatg atattgagaa cttctttaaa gtactaaaag ctgcattaaa
     5521 tcattataac gtcacattac caatgtcatg attgcagaaa tattattgaa gattcgtctt
     5581 ttttattttt cccttcgtgg tatacacttc cattcggaaa gtgttatttc tggagtgcct
     5641 attcgtagct ttcgcttagt aggcaaatat agcaatattt aatttgaggt gatgcattag
     5701 gagttcttta ttcttataaa aaggcatcgg tagttatagg agataatgtt tgtgtagggt
     5761 aatttgcttt tagtgggaga gaccatatta gaattgcggt aaggggcgaa gaagataata
     5821 accaattagt gagaatattg gaaaaatata attgatatcg gtaaatgtag ttgtttttat
     5881 actgtattta agtaatggaa aatctaaagc agaaaactgt atcaggaata atgtggagcg
     5941 ctatagaacg tttctcttta caaggagtac agtttataat tcaaataata ttagctcgtt
     6001 tgttactacc atcggattat ggtatgatcg ggatgttagc tatttttctt caagtcgctc
     6061 aagtatttat agatagtggt tttacaaatg ctttaatcca gaaaaaagat agaactgaag
     6121 aggattttgc cactgtcttt tattttaata ttcttgtcgc agtattattc tatggtatat
     6181 tgtttttttc ggctcctttg attgcagact tttataatat gccgacttta gttcttgtaa
     6241 ttcgttttat agcattgtcg ttgataataa atgctttatc ggctattcac agaacgaaat
     6301 taattatttc tgtaaacttt aaaactcaat ctaaaatttc attaggggca gcttttatat
     6361 caggcgtgat tggaatatgg atggcttatg tcggttgcgg ggtttgggct ttagtttggc
     6421 aaactctctt aaatagtata attttgacaa ttttgtttta ctgtttagtt cattggaaac
     6481 ctttacatac tttctccaaa agttcttttg aaagattatt caatttcgga tctaaattat
     6541 tgatctcaag tcttatcaat acagtatatc gtaatctgta taccattgta ataggaaaaa
     6601 agttttctgt tgtagagctt ggttactata caagagcaga acaatttgct atttttcctt
     6661 ccaataattt aaatgcttta gtttctagag tagcgtatcc tattttaagt tccattcaag
     6721 atgatgataa atgtttaaca aacgcatatc gaaattatat cagattatcc tcatatataa
     6781 tttttccttt aatggtaggt ttacttgttt tggctaatcc tattattagt ctattgttaa
     6841 cagataaatg gtctggggtt gttattcttt tacagatatt atgtttggat tggatgtttg
     6901 atcatttgag ccaaattaat ttgaatttat tatgggttaa aggaagatct gatctgtcgt
     6961 tacgtcttga aataataaaa aagacgattg ctatattcat tctttttgtg tcaattccat
     7021 ttgggcttga ggtgatgtgt tggggtaggg ttatttactc tctgatagcg acatatttga
     7081 atacatatta tactaattct cttattgatt tgaccttaaa attgcaagtt aaagatgtat
     7141 ttccaagttt aatactctct ttcataatgg gagggatcgt ttttatatgt atttctttct
     7201 ttgaaactga tatagtaaaa attgtgattg gatgtattac tgggatgtcc ttttatattt
     7261 tactttcttt tctttttaag ctagattctt ttttttgtat tttaacattg atcattaaaa
     7321 ctaaaaacat agatgaaaat attaaaaaag atttttctaa taatagtaaa gataattaac
     7381 cattgtgtgc cagttgatag tagatcattg tattttattc ctcatcctaa ttgtagaaca
     7441 gataaatatg atattataaa ttattcgtca gataatgttc tcgttctgtt aaattatttg
     7501 ctaaaaaagg atagtgctga atattataaa atatatgttg aaatttatga ttcttctcgt
     7561 atttcagaat atcaagaata tatttatggt ataaatccta atattaggtg tactttttta
     7621 tgtgcatgtg ttggacgttt tttctttaat aaagtatctt ttaaggatat gttgtatgcc
     7681 tttttttgtt tttgtagagc aagtaaatgt tttacagcta ctttttatta tgatttttca
     7741 tttaaaaaac gctctcaaca gattatttgt ttggggtatt atactccatt caaagatgat
     7801 tatcatatgg gagatcattc ttatgataaa tttcgtaata caacatgtaa ctcatttgat
     7861 tactctattg ctacttcttg tttaagtgct agaataattt caatagattg tggaatctca
     7921 tatgataaat tcaaagtctt aggatttccc agaaatgatt tgttgatatc gaaaaataat
     7981 tgcaatgttg ttaaaagaga aatttcgaaa tttgcgggat atgatgtaac taaatatata
     8041 gtttatactc caacttttcg tgattatgag actgttactg aaggtaattt gcgttcaata
     8101 ctcggatatg ttgattgtga tttgttgaag ttatcgaaaa tactattgaa gtttaatgcg
     8161 gctttaattc ttaaattaca tcctttgcag aataaaacag tcttaaaaaa agatttaccc
     8221 aaaggtatac ttgtttttga acaaacatat aaatatggat tgtatgatct tttatcattt
     8281 tcagatggaa tgattactga ttatacttct acctattttg attttttatt agtaaataag
     8341 ccagtcatat ttaatttcta tgatattgaa gaatatcgta gagtaagagg tttctcattt
     8401 gagccaatag aatttttttg tgcaggtgat attgtttaca attataatga attgatagat
     8461 gctgtgatgg gacttctggc tgggaaagat attcatgctg aatatcgacg tcatatttct
     8521 ttattgatga ataaatttca agatgataat tcaacagaga gaatatgtga catattttta
     8581 aatgaaatat aataaataaa atgaattatg catttgtggt gcaggcacgt ttaggttcta
     8641 cacgtttgcc tggaaaaata ttgaaacctt tctatggtaa tcaatcgatt cttgacttaa
     8701 tggttcataa gctttctgct atatcgaata tcccagtaat tattgctaca acaaattctg
     8761 ttatcaatga acctattgaa aagaaggcac ttgcattagg ggtaaagtgc ttcagaggtg
     8821 aggagaatga tgttttaaaa cgattcattg atgttgctga atattttgat atacagggta
     8881 tattccgaat atgttctgat aatccatttt tagatgtaca tgcggcaagg caattggtcg
     8941 aaatagcaat gaaatcttgt aacgattata taagttttga tattgatggt actccatcaa
     9001 ttaaaactca tttcggtttt tggggagaat ttgtaacgct tgatgcgctg aagcgagtta
     9061 taggatttac tgatgattta ttgtatcgtg agcatgttac taattatata tatagtcatc
     9121 ctgaactttt taatattcaa tggatttcag gatctccagt cgtgtcaaaa catcataata
     9181 ttcgactcac gattgatacg ttagaagatt tttctgtagc acagagaata tatagggatt
     9241 tacaagaaaa aagagtggaa atatcgatag aagtgattgt agactatgtt cgaagacatg
     9301 cagaatacat tcaactgatg aaacaacaaa taaaaaaaaa ttctaaataa tgaagaatac
     9361 ttatattatt ggtgaaatag ggcagaatca taatggttct gttgacttgg ctaagttgat
     9421 tattgaatta atctcaagac ctgtacatga ggatgttttt ggtatggatt tcatgccaat
     9481 gaatgctgtt aaaatgacta aaagagattt atcagaagaa ttggctgttt ctcaaatgaa
     9541 tcaaatatat gacaatccta attcttttgg gcgtacttat ggtgaacatc gtgcttttct
     9601 tgagcttgat gatcaagcgc attttgagat ttataaatat gctaagtcat taggattaga
     9661 ttttatcgag acgttatgtg ccaaaggatg tctgtctttg cttaaactgt tcacaccgga
     9721 tagactaaaa gttgctagtc gtgatttgac caacttacca ttgcttgaag cattagcaga
     9781 aactcatatt cctattatat tatcgacagg aatggctggt caaagagaac ttgacaatgc
     9841 attagatgtg ataacgagat atcatagtaa tatagctatt ctacattgtg tatctcagta
     9901 tccaactcat ccaaataatt tgaatctacg tacaataaca tatttgaaga agcattacaa
     9961 taagtttgag ataggttttt ctgatcatac aataggtatt tctgctgcta cagctgctgt
    10021 agcgatggga gcggaaatta tagaaaagca tgtaacaatt gatcggcata tgaaaggaac
    10081 agaccagctt ggctctttag gtccagatgg ggttaatcgt atgattcgag atattcgcat
    10141 tgcagagtgt tggcttggta ctgaaggtct ttatatagaa aaaggtgtgg agaagtctaa
    10201 gataaaactt gaacgttcta ttgccactcg aaaatatatt ccagcaggta gtattattca
    10261 agagtcggac attcatttac tgagtcctgg tgatggttat aaatggatag ataaagaaaa
    10321 tgtaattggt cattttgcta agcaagatat atcagcaaat gaaataatat atcctgattt
    10381 tattgaatag atatattcct attgcaactt gtattacggt atagagtact gcctgctata
    10441 agctgagtag ttattaataa ataagggtaa aatactaaaa aaatgaaaga gataaagctt
    10501 atacttacag atattgatgg cgtttggact gatggcggaa tgttttatga t
//
