LOCUS       c00019_gnlPro..        16540 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EKFECMEK_27.
ACCESSION   c00019_gnlPro..
VERSION     c00019_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 09:36:03
            Original ID  :: gnl|Prokka|EKFECMEK_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 80393
            Orig. end    :: 96933
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16540
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[90393:93366]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16540
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16540
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             709..2463
                     /locus_tag="ctg19_66"
                     /transl_table=11
                     /translation="MIMKKYIFLIVTVVCLFACKDGDEVRQTTSPEASFSIDKEEYTVG
                     DIVYLTDESVKTEGEIVEYFWHFGFEGEGNRATTKDASVLYKRAGTYVIKLTVTDEFGG
                     YATASHTVVIRPTNMPPVTNFSYSPAICKVNEKVQFTDKSVDEDGEIVSYEWDFGNGQT
                     SQEKDPEITFTTTGFVTVKLTATDDRGATNTKQATLYVRDTSISGVTVLWDKTFEVSSS
                     LRSISPAVGDNGDVYVSSNALHLFAYSPSGEQKWMFDLSKDGGAGDQGSSPMIGADGTI
                     YMGASTTDKNISSSLYAIHPDGTQKWRYELGIGTNIPYISPALSRDGNILIGNRGTDGS
                     VHMVDRSSGRQLWRRKSPNGGANGGISVGQNGVIYSALSGANGFARTTQDGVNLSPNLG
                     KGNTAAAVYPAIDAQGNVYVAFSEGVVAAYDNQGNELWRYPASGTMGKIDQGGPAIGAD
                     GTIYVGTKNPNAQVVALTKGGAKKWSYSSVAEIGTTPAIDSDGNIHICDDDGNYIILNA
                     DGTEKYKRQLGSKIWSSPVIADYGIVYVTYEDNGACKLIAIDCGIEGPANSPWAQRGQN
                     AKRNALQK"
     CDS             2470..3375
                     /locus_tag="ctg19_67"
                     /transl_table=11
                     /translation="MLRKINILIALTLLIIGGLEAQNHSDKIIANLQKPASNSVLVVSH
                     RADWRNAPENSLQAIQNCIDMGVDVIEIDLKKTKDGHLILMHDKKIDRTTTGKGYPADY
                     TLEELRQFRLKSGTGHKTAHLIPTLEEVMSLCKGKILVNIDKGYDYFKDVYAVLKETGT
                     VQQCIIKAGLPYEQVKAENGDVLDKVIFMPIVQLHKDGAEAVIDSYQTHMKPAAYELVF
                     DSDSPEILNLIKKVRNTGSNLFINTLWPELCGGHDDDRAVELHQPDESWGWIIGQGAKL
                     IQTDRPALLLEYLREKKLHD"
     CDS             3389..4744
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 154.9; E-value: 8.8e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg19_68"
                     /sec_met_domain="MFS_1 (E-value: 1.2e-47, bitscore: 154.9,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKQLINFYKVSSPRPCNGEALSSSDARRLKFLKWSTFLSATFGY
                     GMYYVCRLSLNVVKKPIVDEGIFSETELGIIGSVLFFTYAIGKFTNGFLADRSNINRFM
                     TTGLLITALVNLCLGFTNSFILFAILWGISGWFQSMGAASCVVGLSRWFTDKERGSYYG
                     FWSASHNIGEALTFLIIASIVSVLGWRYGFFGAGIVGLIGALIVWKFFHDTPESMGFPS
                     VNVPKQKKEMSETETADFNKAQRQVLLMPAIWILALSSAFMYISRYAINSWGVFYLEAQ
                     KGYSTLDASFIISICPVCGIIGTMFSGVISDKLFGGRRNIPALVFGLMNVIALCLFLLV
                     PGAHFWIDVLAMVLFGLGIGVLICFLGGLMAVDIAPRNASGAALGVVGIASYIGAGLQD
                     VMSGILIEGQKTVQNGVDVYDFTYINWFWIGAALLSVLFALLVWNAKSKEVD"
     CDS             4871..5005
                     /locus_tag="ctg19_69"
                     /transl_table=11
                     /translation="MENSLNDKLLCSLKDELREVTAQINVHSEKLMDLLDQKKESLVN"
     CDS             5014..5259
                     /locus_tag="ctg19_70"
                     /transl_table=11
                     /translation="MSHLTPVIIEYRGNPKQYVSVVLDAINLGRLTYDGVANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             5309..5671
                     /locus_tag="ctg19_71"
                     /transl_table=11
                     /translation="LQYGKPQRNLRTYGGYVEAFMETLTEKEQDKIQYGLLLLKTQERL
                     STKFVKFVQDGVFELRTEYNGNIYRVFFIFDDGNIVVLFNGFQKKSQKTPGSEIDKALK
                     IKEEYYADKQSSNSRL"
     CDS             5637..5939
                     /locus_tag="ctg19_72"
                     /transl_table=11
                     /translation="MQINNHQIVDYDAVLDAKFGAEGTPERAEAEEKAYAFYTGQIIED
                     ARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             5957..6187
                     /locus_tag="ctg19_73"
                     /transl_table=11
                     /translation="MVGNLKKITVFFKFPTVFLRKKKEKVRVGEGKFLTFVFFLEENRR
                     IEIRNIKMKSCKSTLTNPHLFACEGDEILFI"
     CDS             complement(6176..8293)
                     /locus_tag="ctg19_74"
                     /transl_table=11
                     /translation="MDHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHASLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRMLQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSITYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPSNKDDLAKIAQAMLINLDEFEGMNGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVNSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(8381..8611)
                     /locus_tag="ctg19_75"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             8805..9308
                     /locus_tag="ctg19_76"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             9329..9496
                     /locus_tag="ctg19_77"
                     /transl_table=11
                     /translation="MKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATHKEVCNVKT
                     TEREKDDEKD"
     CDS             9483..9929
                     /locus_tag="ctg19_78"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVSELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIEEFES"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_79"
                     /sec_met_domain="Radical_SAM (E-value: 3.1e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10745..12973)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_80"
                     /sec_met_domain="Gly_radical (E-value: 3.5e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSSELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             complement(13127..14269)
                     /locus_tag="ctg19_81"
                     /transl_table=11
                     /translation="MEIDLISAKNRAEESNRLKSAFLANMSHEIRTPLNAIVGFSGILA
                     STEEEEEKREYVSIIENNNTLLLQLISDILDLSKIEAGTMDFLYTDFELNKVMEELEQS
                     LRLKLSPDREVTLTLTTPQPECYIHAERNRISQIIINLVTNAIKFTETGSIHFGYEIRE
                     KEILYFYVTDTGCGISEDKQESVFGRFVKLNSFVQGTGLGLSICQTLIQQMGGEIGVHS
                     KTGKGSTFWFTLSYHPTLQAPQQEAAEEPVKIKKQKICILVAEDHSSNYRLIESILKKD
                     YNLVHAWNGEEAVTLFKEHNPQLILMDINMPVMDGYEATKEIRKYSQRVPIIAVTAFAY
                     ASDEQRVMENGFDAYMPKPINANQLKGQISSILMKHITFM"
     CDS             complement(14305..16245)
                     /locus_tag="ctg19_82"
                     /transl_table=11
                     /translation="MRSIFKVSILFLCLLTHSFLSAGNLPEKNIKHILIISAYADSNPW
                     SNSFITPIVTMASQDSTIGVYTINLKMFAVQKNSVNVEKFEEGICEKLPQYTPKMVVFI
                     GNASFVFCDNLNKIWPDIPMLLCGERDYTGPDSLIIEAHPLTPQQRIPISDLQKTMNLT
                     MMHAKLYMEENLQLMKQLIPQMKKVIYIADGTYMCQQNNYDLSTIIKEKYPELDYQLIS
                     AEDTSTDSLFAILNQQNPRTTGLIFSSWLRRKDYEDNLVMTTNSHRIIATSPVPLFSFR
                     KVGIQEEGGIVGGYIYNEKKYIDRMLKTIKDILHGQQPRYTPIYHAEDATPIFNYQSLI
                     QRNLDPKRCPGNTIFYNAPPTFWEKYEYTIIGIACLVILLLLFFQYHRVRVLEKMKRIQ
                     HKELESTGKYYNIINNMPILYMVEELIKNDDGRIVDTMYVDVNKHFEKKFFEKHQIIGK
                     RGSEIFPESLPQFLHFMNIALKEKRSITFSYYYKEIDTFYDVVVNASNDGRFMDVFCMD
                     STELHHAQMQMRSINHKLSMALDIANIIPWKWDLKTHTIHYDVNKALSNENQEINDEQL
                     SMSDEQYFAKIHAEDLPKVKEICTNFITGHCKKAKLEYRVLNNVNGAKRIDWIETQIAI
                     DSYDENGQPKL"
ORIGIN
        1 tagggggagc tgtagatatt gtagaagtag atcctcgcat gacaaaggat ggagtaattg
       61 tgttgatgca tgatgaaacc atagacagga caactacagg gaaggggaaa gtgaaagatt
      121 tgacttatga gcagctccag tcttatcgtc tgaagctggc agacggcaca gtaaccaatc
      181 acacggtccc ctctttgtat gacgcattgg ttgcagggcg gggaaagatc ttttttgatt
      241 tggacttctt gaataaagtg tctcctaaag aactgtatga tgttgtgaaa agctgtggga
      301 tgttagaccg tgtgttcttt tatacatcta ataatcggga tgtcttgcag aatattttgg
      361 attattcgcc ggctcctata ccttatccgc agtgtgaaaa cgaggagcat gcagatttcc
      421 tttcacagca accaggagtg atgtttgccc agatatcttt gtcgaaaaca ttaaatggcg
      481 ggctctcgac agccatatct tcaaaagggc tgtttgtctc gactaatatg ttagatatga
      541 atggttatac ctatgataca cagatgacac aaggaaacta tacaggagtg gacttgattt
      601 tgtcgaaggg gattaatttg atacagacag accatcccca gttgctggat gcctatctga
      661 aacagagagg taaaagataa ttggttttaa tcttaaataa tgaatagaat gattatgaag
      721 aaatatatat tcctgatagt gacagtcgtt tgtctatttg catgtaagga cggcgatgaa
      781 gtgcggcaga caacctcccc ggaggcttct ttttctatag ataaagaaga atatacggtc
      841 ggtgatatcg tttatctgac tgatgaatca gtaaagacgg aaggagagat agtagagtat
      901 ttctggcatt ttggatttga gggggaaggg aatagggcta ctactaaaga tgcgtccgtt
      961 ttgtataaga gggctggaac ctatgttatt aaattaaccg tgacagatga attcggagga
     1021 tatgcaactg catcccatac tgttgtgatt cgtccgacga atatgcctcc ggttacaaac
     1081 ttcagctata gccctgccat ttgtaaagtg aatgagaaag ttcaatttac cgataagtct
     1141 gtggatgagg atggagaaat tgtttcttac gagtgggatt ttggcaatgg gcagacttct
     1201 caagaaaaag acccggaaat aactttcacg acaacaggat ttgtaactgt aaagctgaca
     1261 gctactgatg atcgtggagc tacaaataca aagcaagcta ctttatacgt tcgtgatact
     1321 tctatatccg gagtaactgt cctttgggat aagacgtttg aggtatcctc ttctttacgg
     1381 tctatctctc ctgctgtagg tgacaacggg gatgtatatg tgtcatccaa tgcactccac
     1441 ctttttgctt attcgccgtc tggagagcaa aaatggatgt ttgatttaag taaggacgga
     1501 ggagctggag atcaaggttc gtctcctatg ataggtgcgg acggaactat ttatatgggt
     1561 gcgagtacaa cagacaaaaa cataagcagc agtctgtatg ctattcatcc ggatggaaca
     1621 caaaagtgga gatatgaact aggtattggt actaatattc cctatatttc tcccgctttg
     1681 tctcgtgatg gcaatatctt gattggaaat agagggaccg atggttctgt acacatggtt
     1741 gaccgtagtt ccggcagaca actttggaga cgcaaatctc ccaatggtgg tgctaatggt
     1801 ggtatatcgg ttggacagaa tggagttatc tattcagcct tgtcgggagc gaacggattt
     1861 gcccgtacta cgcaagatgg tgtgaacttg tctcctaatc tagggaaagg aaatacggct
     1921 gctgctgtat atcccgctat tgatgcgcaa ggaaatgtat atgtggcatt ttcagaggga
     1981 gtggttgctg cttatgataa ccagggtaat gagctatgga gatatccggc gagtggtact
     2041 atgggcaaga ttgaccaggg aggaccggct atcggtgctg acggaaccat ctatgtgggt
     2101 acaaagaatc cgaatgccca agttgttgcc ctgactaaag gaggagcaaa gaaatggagt
     2161 tattcctctg tcgctgaaat aggaacaaca ccggctatag acagtgacgg aaatattcac
     2221 atctgtgatg atgacggtaa ctatataata ttgaatgctg atggtacgga gaaatataag
     2281 agacaattag gttctaaaat ttggtcgtca ccagtcattg ctgactatgg tattgtgtat
     2341 gtcacgtatg aggataatgg tgcctgcaaa ttgatagcta ttgattgtgg tattgaaggg
     2401 cctgcaaatt caccatgggc acagcgcgga cagaatgcaa aaagaaatgc tttacaaaaa
     2461 taaaaagata tgcttagaaa gataaatata ttaatagctt taacccttct gataatagga
     2521 gggttagagg cacagaatca ttcggataaa ataattgcga atctacagaa gcctgcaagt
     2581 aattcagttt tagttgtttc tcatcgagct gactggcgta atgctccgga gaactccctg
     2641 caggctatcc agaattgtat tgatatgggg gtagatgtaa ttgaaatcga tctgaagaaa
     2701 accaaggatg gacatctgat tttgatgcat gacaagaaaa ttgatcgtac tacaacagga
     2761 aaaggttatc cggcagacta tacattggaa gaattacgtc agttccgttt gaaaagtggt
     2821 acagggcata aaacagctca tttgataccg acattggaag aagtaatgtc attatgtaaa
     2881 ggtaagatcc ttgttaatat tgataaaggc tatgattact tcaaagatgt atatgctgtt
     2941 ttgaaagaaa caggaactgt tcagcaatgt attattaaag ccggacttcc ttatgaacaa
     3001 gtcaaggctg aaaacggtga tgtattggat aaggtaatct tcatgcctat tgtacaactt
     3061 cataaagacg gggcggaagc tgtcattgat agttatcaga cacatatgaa acctgctgct
     3121 tatgaattag tgtttgatag tgacagtccg gagattctta atttgataaa gaaagtacgt
     3181 aatacaggct ctaatctttt tataaatacg ctttggcccg aactatgtgg cgggcatgac
     3241 gacgaccgtg cagtagaact tcatcagccg gatgaaagtt gggggtggat aattggccag
     3301 ggagccaagc taattcaaac agaccgccca gctctattat tagagtatct acgcgaaaag
     3361 aaacttcacg actaaacgca ctttcttcat gttgaaacaa ctaatcaatt tttacaaggt
     3421 ctcttcgccg agaccttgta acggagaagc tttgtcttca tccgatgctc gccgtctgaa
     3481 gtttctgaaa tggtctactt tcctttctgc gacttttggt tacggtatgt attatgtgtg
     3541 ccgtcttagc ctgaatgtcg taaagaaacc tattgtagat gaaggcattt tttcggaaac
     3601 agagttaggc atcataggtt ccgtattgtt tttcacctat gccatcggaa aattcacgaa
     3661 cggtttcctt gccgaccgta gtaatatcaa ccgttttatg actaccggtt tattgataac
     3721 tgctttggtt aacctctgtc tcggttttac taattctttt atcctgttcg ctatcctttg
     3781 ggggattagc ggctggtttc aatctatggg agcagcctct tgtgtagtag ggctttctcg
     3841 ttggttcacg gacaaagagc gcggttcata ctatggcttt tggtctgcga gccataatat
     3901 cggcgaagcg ttgacttttc tgataatagc ctcaattgtc agtgtgttgg gctggcggta
     3961 tggtttcttc ggagccggta tagtgggatt gataggagcg ttgatcgtct ggaagttctt
     4021 ccatgatact cccgaaagca tgggatttcc ttcggtgaat gttcccaaac agaaaaagga
     4081 aatgagtgag acagaaacgg ctgattttaa taaagcacag cgtcaggtat tgctgatgcc
     4141 tgccatttgg atactggctc tttcgagtgc ttttatgtat atcagtcgtt atgctatcaa
     4201 tagttggggc gttttttatt tggaagctca aaaggggtac tctacattgg atgccagttt
     4261 tatcatttct atttgtccgg tctgtggtat aatcggtact atgttttcag gtgttatttc
     4321 tgataagtta tttggtggac gtcgtaatat tccagcttta gtatttgggt tgatgaatgt
     4381 aatagcactt tgtttgtttc tcttagttcc gggagctcat ttttggatag acgtgttggc
     4441 aatggttctt ttcggtttag gtatcggagt tttgatctgt tttctgggtg gtttgatggc
     4501 agtggatatt gctccccgta atgcttcggg tgctgcattg ggagtagtcg gcattgccag
     4561 ttacatcggt gccggattgc aggacgtgat gagcggtata ctgatagaag ggcaaaagac
     4621 tgttcagaat ggagtagatg tttatgactt cacctatatc aattggtttt ggattggtgc
     4681 tgctttgctt tctgtgttgt ttgctttgct ggtatggaat gcaaaatcaa aagaagtgga
     4741 ttaaagtgag tacattaggt tagaatataa gtctttgttt tcgaggtatt agacaccatt
     4801 ccgggaagta agtaatgatt gcttatcttt ctggaatggc ttttttataa tcaattaaat
     4861 aaaaagtttt atggaaaatt cattgaatga taaattattg tgttcattga aagatgaact
     4921 tcgtgaagta actgcacaaa tcaatgtgca tagtgaaaaa ttaatggatc tgctcgacca
     4981 aaaaaaagaa tcgttggtca actgactcga gagatgtcgc atctcacgcc tgtcatcatc
     5041 gagtatcggg gaaatccgaa gcaatatgtc tctgttgtgc tcgatgccat caatctgggt
     5101 aggttgacgt atgacggagt agcaaattgc gaacagactt ttcgtgcgtt agcaagcgtt
     5161 gtagatgtga taagccctaa gaatgggaaa acgcttagtg tagagacgct ggtgtcttat
     5221 gagaagaaaa agcgtgcagg agaatttgag gaaaaataat ataaaataaa aagatgattg
     5281 ttgtatagtt gaacaacaat tcgcatattt gcagtatgga aagcctcaac gtaacctccg
     5341 tacatacgga ggttacgttg aggctttcat ggagacttta accgaaaagg aacaagataa
     5401 aatccagtat ggactactct tgttgaaaac acaagaaaga ctctctacta aatttgtaaa
     5461 atttgttcag gacggagttt ttgaacttcg tacagaatat aatggtaata tataccgggt
     5521 atttttcatt tttgatgatg gaaatattgt agtgttgttt aatggctttc aaaagaagtc
     5581 gcaaaaaaca ccgggtagtg aaatagataa agcattaaaa ataaaggagg aatattatgc
     5641 agataaacaa tcatcaaata gtagattatg acgctgttct tgatgcgaaa tttggagcag
     5701 aaggtactcc cgaacgtgcg gaagcagaag aaaaagcgta tgctttctac accgggcaaa
     5761 ttatcgaaga cgcaaggaaa aaggctaaga ttactcaagc agagttagcc cggcgtatcg
     5821 gttccgaccg ttcttatatt tcaagagtgg aaagtggtca gacagaacct aaggtttcta
     5881 ccttctatcg tatcatgaat gcgttaggtt gtaggataga attttcgatg tctttataag
     5941 aagcgattaa aaaaacatgg tgggaaattt gaaaaagata actgtctttt tcaaatttcc
     6001 caccgttttt ttgaggaaga aaaaggaaaa ggtgagggta ggtgagggta aatttctaac
     6061 attcgtattt tttttagaag aaaatagaag aatagaaata agaaatataa aaatgaaaag
     6121 ttgcaaaagt accctcacca accctcacct ttttgcgtgc gaaggagatg aaatcttatt
     6181 catatagcct gtttgatttc acctgttccg tatcaataat gaatacagtg tatcttctcc
     6241 cgttttttcc cttatgaaat tcgaagccgt gtttggacat cacttttcct agttgggctt
     6301 tggttccgtg agaatattga taccccgtcc gttcgcgaat caattccgca atttcagtga
     6361 ccgtcagata atgcaccttt tcgaaacgtt ccggtttgcg gatatgtgtc aacaccagtt
     6421 cttcttccgg tgagtggaaa atgaaatcct cgttgttttc ttcaatccgt gagttttccg
     6481 actgggtgaa ccaatactga taccccggct tgttgagcag atacttgatt tgtgcataca
     6541 actgcgcgta gtttattttg ataaactcca tcgagttgac atgaaagcag agaaaacggc
     6601 ggttacctgt ggtgtcgtga agcacttcct gataattgca tgtgccggca aaagaagccg
     6661 tgtgaggaaa gttctgcgaa cgccgcgcgt atggcaggcg gatgctgatt actttgcggg
     6721 taactaaatc cttgaagata ttcagttccc gtccgttcat cccttcaaac tcatccagat
     6781 tgataagcat tgcctgcgct attttggcta gatcatcctt gttgctcggg ttgataagac
     6841 cggtagaaag ataggcgcgc aattcgggcg gcagcaggtt gttgataaac gtagtctttc
     6901 cgatgttctg tatttcgctg caaagcaaca aaacagtgtg gttcaccaca tcatcttgtg
     6961 tggcggcagc gcacattccc accagataac gttccagaca ttctacccaa aatttctggt
     7021 gactagtatg cacgctgttg gcaaggatac cgatataatc cgttccgtcc cattcaggca
     7081 gcgagtctaa atactcgcga ataggatggt aggtgatgct gaagtcggag tagatcagat
     7141 tctgaatcgt cttgacggtg cacgaatagc ccagttcgtt catctccatc caaatgctgt
     7201 tttccatcat ttcgtcgaga atatggaaag gttccggttg ctccgtgtcc gttttccttc
     7261 tgcgatattc catgatatga agcacttcgt tgtagcgtgt atcgtaattt tctttgatat
     7321 gttgctcaat ctgtaacatt cgcttctgcg tactattcag cttgcgggtg tcgaattcct
     7381 cgttgtgtcc gtaagcactc ccgatcagtg cgtccatttc atccgcggga agatcggtga
     7441 actggctctt gataaaagct gccgcctctt cctgggggac gccgtagcga ttgtacatac
     7501 aagccaggca atgcaggtag ttgttccggt tgccggtgac gtacttttcg gatttattgt
     7561 gataatagtt cagagtcacc attaaggaag cgtgcgagga atggtagttg agtgccactt
     7621 gttcggtgag gggattgttg tctggtgctg tcgtcttttt ctttttgccg gatgcccttt
     7681 tcttcttttg agacttgaag aacatcggtg gctgttccac gatgacagct gtggcatcgg
     7741 gattgaaata aatatccgga tcgtaagaga acaggcaagt gcggctaaca tcctgcccgg
     7801 aagtgtcgac ctcaactccg cagagctggg cataaaagga agcgattttg tgataagcag
     7861 catgatggaa atcttcaatt tcctgaattg tttcgggcaa tgtcccgtct gtccggcata
     7921 cacgtaccac gattttcagt cccattcctt tggggctgat gaaagcgatg cgggtgtggg
     7981 cacacttttt tgccagtgcg aggatgcgtg ccaatgcttc ctgtgtctga tggtcgatgt
     8041 ctactacgat gtatcccaga tacttgacga gagttgcgtt tgaacgtcct ccccggtagt
     8101 tggctgaaaa ggtgatttcc ggtagttcta ttttcttttc gttggctgct ttctcgcctt
     8161 gttccgcgaa gattcggcgc acgtcctcca ccgtttcccg gtatgtgccg ttgctgatgg
     8221 ccgatacgat ttcttcttct gtcatttcgg ctatgacgcg gtaaaagtct tgaaagatgg
     8281 taaaatgatc catgttggtt tgttcttttt aatttgcggt tgcaaagaaa tttgtttgta
     8341 aaataataga atggaacttt tcgttttttt gattaagttc ctagggttct cccaaatagc
     8401 gtatgatcgt tgccacttgc cggggagaga gaaggcggtt gcgggcacga tagccttctt
     8461 gttcgagttc ttgcaggagc ggaaggttgt agacaatcca acgacgtagt atttgtaagg
     8521 ctactttaag gcatacgttg gggttgtaaa gatgagctag ttccgacttt ttataagtgc
     8581 ggatatgaaa cggctgatcc ggataataca tgatgaatgg tatttggttt atgctataaa
     8641 gttactgaaa attaatggct tattaaaaga ataacgtcat tattattcat agagtatcag
     8701 gaaacttcgt tggggaatcc ggaggatgga aaatgtgtta tctttatgtc gttaacaaat
     8761 aaggaacgcg ttcgaaatgt atgaaaattt aaaattattt tattatggca atgacagtaa
     8821 cttattcagt agtgccgcgc aagaatcctg ccaaaaagga tgagtcggca aagtattatg
     8881 cgcaggcaca ggcttcggga gagttggatt ttgaagagtt gtgcgaggga atcaccagcc
     8941 ggtctacctg tacggagaca gatgtgcgtg ccgccatttc gggtattctt tatgaggcga
     9001 agcgtgcgtt gaaagcggga agaatagtcc ggctgggtga tttgggtagt ttgcagatcg
     9061 ggttgaacag tgaaggagct gtgtcggtca aggagttttc aagttcgctg attacggctg
     9121 cccatattat ttttcgtccc ggaaagacgt tggcggacat cacgaagatt cttagctacc
     9181 agcaggtaac gacgcgtgcg gtggcccaaa cgggcggtag cggcaatgaa ggagaagacg
     9241 atgacaaagg ttccggtggt ggttcagacg gtggtggaag cggagaagct ccggatccgg
     9301 cagcatgata actttaatat tagatcaaat gaaagaaatt gtaactaaga ttttggatgt
     9361 aatcatgttc cttgtgcctt tcttcggaaa aagaaagcgg aacagaattg tgagagaggt
     9421 gcgcttcaat gctacccata aggaagtgtg taatgtgaaa acgacggaaa gggagaagga
     9481 cgatgagaaa gattagtctg attgtgattc actgctctgc tacccgtgtc gatcgcgact
     9541 tcacggcgaa ggatgtggac actgcccatc gctttcgggg cttttcgtgt tgggggtatc
     9601 attattatat ccgcaagtcg ggacagatag aaccgatgag ggatgaagat acggtgggtg
     9661 ctcatgcacg cggttttaat gcgattagtt taggggtgtg ctatgaaggc gggctggatg
     9721 agaacggaaa ggcagcggat acacgtactt cccgccagaa agaggcgatg catcgtctgg
     9781 taagcgagtt gttgcagcgt tatccggatg caaaggtggt cggtcaccgg gacttgagcc
     9841 ctgacaccaa ctacaacgga attgtagacc cctgggaacg gatcaaagaa tgtccctgtt
     9901 ttgaggtgat tgaagaattt gagagttgag aatggagagt tgagagttgg ctgcgcactg
     9961 ttatactgca tagttaactc tcaattctca acttcttcaa ctaattgacc accacagtag
    10021 tgaaatactc tttaaatacc tccgcggctt tttcaagttg ttcgggggta ttttctttta
    10081 cgtctttcag tttgtattcc tgctccatcg cttcatactt atgtacgcct aatgtatgat
    10141 aaggcaggat ttccactcgt tgcaccatct tatattttcc cagagcctct cctaaacggc
    10201 ggatgtcttc ttcgaaatcg ctgtatccgg gcactaatac ataacgcagc cagaaaggtt
    10261 tctcgttttc ttccagccat gctgccgtgc ggatggtttg ctcgttactt cttccggtca
    10321 gtgcctgatg gcgtgccgga ttgaactctt taatatccag caatacaaga tccgtcagtt
    10381 tgaaaagttc ttctacttct tcgttccaga taccgccgtt gctgtctatg catacatgta
    10441 ttcccttttc tttcagttca cgcaccaggg gaaccagtgc tttggcctga aacgtaggtt
    10501 ctcctccgga gaaagtgact cctccgcgtt tcccgaaaaa aggacgttgg ctcatagcca
    10561 tgcggacgat ttcttccggt ggggtaggtg tacctccttt tccggctatc gtgtcgggat
    10621 tggcacaata caggcagcgg aaattgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcgtcata ttgagtagat
    10741 ctgattacat acgttcgtgg aagctacggc tgattacttc caattgatgt tcgcggctca
    10801 acttcacgaa gtttacggca taaccggaaa cacggatggt aagctgcgga tatttttccg
    10861 gatgctccat ggcgtcgtaa agcatctcac ggttcagcac atttacgttc aagtggtgag
    10921 cgcctttggt gaagtaacca tccatcattg tcaccagatt ttctacgcga tcctcttcag
    10981 tagctcccag tgatttcgga acgatggaga aggtgttgct gataccgtct tgtgagtcgc
    11041 ggtaacgcaa tttcgctacg gaactcaaag aggcgatagc accgttcttg tcacgtccgt
    11101 gcatcgggtt ggctcccgga gcaaaagcga cacctttggc gcgtccgtcg ggagtagcac
    11161 ctgttttctt gccatacatc acgttggaag tgatggtgag caaagacaga gtaggacggg
    11221 catttttgta aaccggaagt ttcttcaatt cttcgctgaa gaaatagacc aggtcaacac
    11281 ccaggtggtc taccttgtcg ttgtcattac cgaagcaagg gaattcgcct tgaatatcga
    11341 aaccttctgt cagaccgatg tcattgcggc gtgcagtcac tttggcatat ttgatggccg
    11401 acagtgaatc gagggcgata gaaagtccgg ctacaccgta agcaaggttg atgcgcgggt
    11461 tggtatctac aagagccatt tgggcttttt cgtagtaata cttatcatgc atataatgga
    11521 tgatgttcat cgcttcgttg taaacacggg cgatttctgt caataccttc ttgtagttgc
    11581 tcattacttc ttcgaagttc agtgtgtcgc tggttagtac ggggatgttt ttcaccatta
    11641 ccgtgccggt gttttcgcaa cgtccgccgt tgatggcaag cagcagggct ttagccaggt
    11701 tgcaacgtgc gccgaagaac tggatttgtt ttccgatttc ctgataagat acgcagcacg
    11761 cgattccgta gtcgtcagac tggcgtactt cacgcatcag gtcgtcgttt tcatattgga
    11821 tggaagaagt gtcgatagat acttttgcgc agaattcttt gaatccttcc ggcagttccg
    11881 agctccacaa tacagtcagg ttcggttccg gtgaagggcc gaggttgtag agtgtttgca
    11941 ggaagcggaa agaagtcttt gtcaccttgg tgcgtccgtc gttgaggcgt ccgcccagag
    12001 attcggttac ccatgtcggg tcgccggcaa agatgtcgtt gtaagattgc atacgcaggt
    12061 ggcgcaccat acgcagtttg atgacaaact ggtcgatcag ctcctgtgcg aaagattctg
    12121 tgatggttcc tttgctcaat tcatattcca tataaatgtc gaggaacgaa gagacgttac
    12181 ctagtgacat ggcagcaccg tcttgttctt ttacggcagc aaggtaagcc atgtacaccc
    12241 attgtactgc ttcttgtgcg gtgtaggcag gacggctcaa gtcgagtccg tagtattcgc
    12301 ccattacctt catgtccttc aatgccttga tttgctctgc cacttcttcg cgcaggcgga
    12361 tgcgggcttc ggtcatcgga ccggtaaggt tacgcaaatc ttcttttttt gcctcaatca
    12421 gtcggtcgat accatagaga gccatacggc ggtagtcgcc gatgatacgt ccgcgggcat
    12481 agttgtcagg aagtccggtg aggaatccca gagaacggaa cgaacggatt tcttcggtat
    12541 atacgtcaaa tactccgtca ttgtgcgtct tgcggtagtg agtgaatata tcttttacac
    12601 ggtcgtccac ttccacgccg ttttcatggc aggctttgct caccacgttg atacctccga
    12661 aaggtttgat tgcacgtttc agaagttcgt ctgtttgcag accgacgatc agttcgtttt
    12721 ctttgtcgat atatccggct ttatgagaag tgatggttga gacggtgaca ttatccagtg
    12781 agcgtactcc gttattggct ctttcttctg ccagtgcttc gaggcagcgg ttccatacag
    12841 ctttagtgcg ttcggtaggt ccttcgagga aagaagcatc tccataatac ggagtgatgt
    12901 tgtgactaac gaaatctctt acgttgattt ctgtgctcca aagaccgtct ttaaagatct
    12961 tatttaattc cataaatgat aaaattagag gttgtagtta tccttttctt tagagcgcac
    13021 aaagttacaa cgttttttca tataatcagc ataaatatgc tctattttat gcttttcaac
    13081 ataaaatacc tagatattgc tattctttgg aaatgacttc ttatggctac ataaaagtga
    13141 tatgtttcat cagtatggat gaaatttgtc ctttcagttg attggcgtta attggcttag
    13201 gcatataagc gtcaaatccg ttttccatca ctctctgctc gtccgaggca taggcaaaag
    13261 ccgtgacggc tatgatggga acccgttggg agtatttgcg tatttctttg gtagcctcgt
    13321 atccgtccat cactggcatg ttgatgtcca tcaggataag ctgcggattg tgctctttaa
    13381 acaaggttac tgcttcttct ccattccagg catgtactaa gttgtagtct ttcttgagga
    13441 tggactctat caaacggtag ttgctgctat ggtcttctgc caccagaata cagattttct
    13501 gcttcttgat tttaacaggt tcttctgctg cttcctgttg cggtgcttga agcgtaggat
    13561 ggtaagagag agtgaaccag aatgtagatc ctttgcctgt ttttgaatgt acgccgattt
    13621 cacctcccat ctgctggatg agggtttggc aaatggaaag tcccaggcct gtgccttgta
    13681 caaagctgtt cagcttgacg aagcgtccga aaacactttc ttgcttgtct tctgaaatac
    13741 cgcatccggt atcggtcaca tagaaataaa gtatctcttt ttcgcgtatt tcatagccga
    13801 aatgtatgct acctgtttct gtgaatttga tggcgtttgt taccaaattg atgatgattt
    13861 gtgaaattcg gttacgttcg gcatgaatat aacattccgg ttgcggagtt gtgagtgtaa
    13921 gcgtgacttc tctgtcgggg gatagtttta ggcgtaacga ctgttccagc tcttccatta
    13981 ccttgtttag ttcgaagtct gtatagagaa agtccatagt accggcttca atcttcgaga
    14041 ggtcgagaat atcgctgatg agttgtaaaa gcaaggtgtt attgttttcg atgatgctga
    14101 catactctcg tttttcctcc tcctcttcgg tggatgccaa tattccggaa aatccgacaa
    14161 tggcgttgag cggtgtgcgg atttcgtggc tcatgttggc aaggaaagca gatttcaaac
    14221 ggttggattc ttctgcccgg ttcttggcgg aaatcaaatc aatttccata ttcttccggt
    14281 cggtgatggt tagagaagaa cctatcagag tttcggctgt ccgttttcgt cataactgtc
    14341 tattgcgatc tgggtctcta tccagtctat tcgtttcgct ccattcacat tattgagaac
    14401 gcgatattcc aatttggctt ttttgcagtg tcccgttatg aaattggtgc atatttcttt
    14461 cactttaggg aggtcttctg cgtgtatttt tgcgaaatac tgttcgtcgg acatggatag
    14521 ttgttcgtcg tttatttctt gattctcgtt gcttagtgcc ttgtttacat cataatggat
    14581 ggtatgtgtc tttaaatccc atttccaagg gatgatattg gctatgtcga gtgccataga
    14641 cagtttgtga ttgatggaac gcatttgcat ttgggcatga tgcaactctg tactgtccat
    14701 gcagaatacg tccatgaagc gtccgtcatt actggcattt actactacgt cgtagaaagt
    14761 gtctatctct ttataataat aagaaaaggt aatggaacgt ttttccttta aagcgatatt
    14821 catgaaatgc agaaattgtg gcagtgattc tgggaatatt tcacttcccc gcttaccgat
    14881 aatttggtgc ttttcgaaga atttcttttc gaaatgcttg tttacgtcta catacatcgt
    14941 gtctacaatc cgcccgtcat cattctttat aagttcttcc accatgtaga ggataggcat
    15001 gttgttgata atattataat atttaccggt gctttccagt tctttgtgtt ggatacgctt
    15061 catcttttcg agtacacgca cgcgatggta ctggaaaaat agtaataata gaataactag
    15121 gcaggcgatt ccaataattg tgtattcgta tttctcccaa aaggtgggag gagcgttata
    15181 gaagatcgta ttaccgggac aacgtttcgg gtcgaggttg cgctgaatta aggattgata
    15241 attaaatatg ggtgttgcat cctcggcatg atagattggg gtgtaacgtg gttgctgtcc
    15301 gtggagtata tccttgatgg tctttagcat ccggtcgata tacttctttt cattatagat
    15361 atagccgcct acgattcccc cttcttcctg tattcctact tttctgaatg agaacaaagg
    15421 gacaggcgaa gtggctatga tgcggtgtga gttggtggtc atcacaaggt tgtcttcata
    15481 gtcttttcta cgtagccagg aagaaaatat aagtccggta gtacgtggat tctgttgatt
    15541 aagaattgcg aagagactgt cggtggaagt gtcttctgcc gagataagct gataatccag
    15601 ttccgggtat ttttctttga taatagttga gaggtcataa ttgttttgct ggcacatata
    15661 ggtaccgtca gctatataaa tcaccttctt catttgagga atgagttgtt tcataagttg
    15721 caggttttcc tccatgtaga gttttgcatg catcatggtc aggttcattg tcttttgcag
    15781 gtcgctgatt ggaatccgct gttgtggagt gagtgggtga gcctcaatga tgagactgtc
    15841 gggccccgtg tagtctcgtt caccacataa caacatggga atgtccggcc atatcttatt
    15901 caggttatcg caaaatacga aactggcatt tcctataaat accaccattt taggagtgta
    15961 ttggggaagc ttctcacata taccttcttc aaacttctct acatttaccg aattcttctg
    16021 cactgcaaac attttcaagt tgatggtata aactcctatg gtgctgtctt gtgaggccat
    16081 cgtaacgatg ggagtaatga aactgttact ccatgggtta gaatcagcat aagcactaat
    16141 aatcagaata tgttttatat ttttttcggg caggttgcca gccgataaaa aggaatgtgt
    16201 gagcaggcaa agaaaaagaa tacttacctt aaatatactt ctcatgttgt ttttcgctta
    16261 taatatgttt attttgccgt gaaaacaggg cgaagatatg cataaaaagc aaatatacaa
    16321 aagaaatatg agaataaatt tgcgagcggt aaatagacta ctttcacggt cttcatcgtt
    16381 tatgcagaaa atatttccga attttttgtc ttaaaaatat ttgcgtatta aaaaaagagt
    16441 tgtacctttg caccgctttt aacaaaaagc acttctgata aagaagtttt ggagaggtgg
    16501 cagagtggtc gattgcggcg gtcttgaaaa ccgttgtacc
//
