LOCUS       gnlProkkaBMOFPBML_72   15161 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMOFPBML_72.
ACCESSION   gnlProkkaBMOFPBML_72
VERSION     gnlProkkaBMOFPBML_72
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 08:59:09
            Original ID  :: gnl|Prokka|BMOFPBML_72
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15161
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15161
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4810:5161]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4811..5161
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15161
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15161
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..131
                     /locus_tag="ctg51_1"
                     /transl_table=11
                     /translation="MAIDVFRNRQREKVARANPLRKQYYEKRDDSDKLKLDTVDED"
     CDS             141..1382
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 387.1; E-value:
                     2e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg51_2"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESLLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             1369..1896
                     /locus_tag="ctg51_3"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1902..2675
                     /locus_tag="ctg51_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2682..3077
                     /locus_tag="ctg51_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             3325..4713
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4.1e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg51_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4811..5161
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_7"
                     /sec_met_domain="PqqD_RRE (E-value: 1.5e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.5e-18, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(5344..5628)
                     /locus_tag="ctg51_8"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(5665..6732)
                     /locus_tag="ctg51_9"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6805..8316)
                     /locus_tag="ctg51_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPITSIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCLTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             9379..9603
                     /locus_tag="ctg51_11"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9797..11341
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 47.2; E-value: 2e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg51_12"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWSFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             11382..11918
                     /locus_tag="ctg51_13"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVID"
     CDS             11978..12547
                     /locus_tag="ctg51_14"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAVDKL"
     CDS             12637..13803
                     /locus_tag="ctg51_15"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVILLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYDDNVDDDDDDIDYEYEEEDWEEK"
     CDS             13800..14612
                     /locus_tag="ctg51_16"
                     /transl_table=11
                     /translation="MISLTKNNELKGYKSLDVYPEVAHFVTTRHEGISTGAYGSFNCSP
                     YTNDSCMNVNRNQSWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLEMRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDHLNQKF
                     GTQGEDVVACIGPSISLESFEVGDEVYDAFKESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNAGVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRILSGIMIRK"
ORIGIN
        1 atgttgccat cgatgtgttc cgtaatcgtc agcgggaaaa agtggctcgt gccaatccgt
       61 tgcgtaaaca gtattacgag aaacgtgacg atagtgataa actgaagctg gatacagtag
      121 acgaagatta aaaacgagtg atgacgagag cagagataca acaagtgaaa caacgtttcg
      181 gtattatagg taataccgaa gcattgtcgc gcgccataga tgttgccatt caggtagctc
      241 ctaccgattt gtctgtgctg attaccggag aaagtggagt cggaaaagaa agttttccgc
      301 agattattca tcaatatagc cggaggaagc atggacagta tattgctgtc aactgtggtg
      361 ctattccgga gggcacgatt gattccgaac tgttcgggca tgagaagggt gcgtttaccg
      421 gtgcgattgg cgaacggaaa gggtattttg gcgaagccga cggtggtact attttccttg
      481 atgaagtagg ggagttgccg atgcctaccc aggcgcgttt gctccgtgtg ttggagagtg
      541 gcgagtttat aaaagtaggt tcgtccaaag tgcaaaagac ggatgttcgt attgtggcag
      601 ctaccaatgt caatctgaca caagcgattg cagaaggacg tttccgtgaa gatttatatt
      661 accggttgaa tacggtgcct atccaaatac cgcctttgcg tgaacgtggt gacgatgtac
      721 ttttgttgtt ccgtaagttt tccgcagact ttgcagagaa ataccggatg cctgctatcc
      781 agttgacgga ggatgcgaag aaagagttat tggcttaccc gtggcccggc aacgttcgtc
      841 agttgaagaa catcaccgag caaatatcta tcattgaaac caacagggag atctctgctg
      901 ctatcttgca gaattatctt cctgcacaaa atacgcaacg tcttcccgcg ctgatgggaa
      961 cgcgtgagag taaaggcttt gagagcgaac gggagattct ttattctgtt ctgttcgata
     1021 tgcgccagga agtggcggag ctgaagaaga tggtgcacaa cctgatggcg gaacgtgccg
     1081 gacaggtggg gcaggtaggg caaatgggaa cggtggttac tactccggta gtgacggcac
     1141 atcaaccttc ggtacctgct atcattcaca ccatgcagcc tacggtttgc aaggatgacg
     1201 atgacataca agacacggaa gaatatgtag aagaatctct tttgtcactg gacgaagtgg
     1261 agaaagaaat gatacgcaag gcacttgaga ggcatcatgg aaagcggaag agtgcggcca
     1321 aggacttgaa tatttccgag cgtacacttt atagaaaaat aaaagaatat gaattggatt
     1381 aagaaaataa tacgcccttt gctactgttc ggcttgccgt tggtagtcat tgcgtgcact
     1441 gtttcctata agtttaacgg atcgtctatc aattatgata aggtaaagac catttcgata
     1501 gccgacttcc cgatcaagtc ggagtatgta tatgctccgt tggcaaccaa attcaatgag
     1561 gacctgaaag atatcttcat ccggcagacc cgtctgcaac tgctcaagcc gagtcaaaat
     1621 gccgacttgc agattgacgg agaaatcaca gggtacaatc agtacaacca ggcagtatct
     1681 gccgacggtt attcttcgga gacgaagttg actatcaccg tcaatgtgcg ttttgtcaac
     1741 aacaccaatc atgccgaaga ctttgaacaa cagttttctg cgttccgtac ctacgactct
     1801 acccagttgt tgactgccgt acaggacgga ttgattgctg aaatgtctaa agagatcacc
     1861 gaccaaattt ttaatgcaac tgtagcaaac tggtaatata aatgacttct gttaactttc
     1921 aacaatggat tcagcatccc gagacgctga atagggatac tttgtacgaa ctgcgcaatc
     1981 ttcttgcgag gtatccgtat tttcagtcac ttcgtctgtt gtatctgaag aatctgtata
     2041 ttctccatga tattagtttc ggtggagaac tgcggaaagc agttctttac attgcagaca
     2101 gacggcagtt gttccggttg attgaaggtg accgctatga tgtgcaggcg cggaaaaagg
     2161 gagtacctct cacggaggtg ctgaaagacg aaccgtccgt agaccgcaca ttagcattga
     2221 tcgacgcttt cttgtccaca gtacccgaag aggtgactgc ccggaccagt ttcgactatt
     2281 cgatggatta cacctctttc cttttggagg agactccggc cacggaacag ccggctgaag
     2341 aaacgcccaa actcaaaggc ttcgaactga ttgacgattt tatagaaaag agcgagagcg
     2401 actctcccct ctgcatgaaa cctttaagag aagaaatgcc atcttcgcca acctcttcgg
     2461 acgaacttac cgaagaagaa acgataaagg aagaagagga agatgacagc tgttttacgg
     2521 aaactttggc aaaaatctat gttaaacagc aacgatattc aaaagctctt gaaataatta
     2581 aaaaattaag cttgaaatat ccaaaaaaaa atgcttactt tgcagaccaa atcagatttt
     2641 tggagaaatt gattattaac gctaattcaa aataactaaa aatgtactta ttattcgtta
     2701 tcttaatggt tattgcagcc ttgttgatgt gtttcatcgt gctgattcag aactcaaaag
     2761 gaggcggact tgcttctggt ttctcttcat ctaacgccat catgggcgtg cgcaagacta
     2821 cagactttct ggaaaaagca acatggggcc tggccatctt tatggttgta atgagcattg
     2881 ctactgctta tgtagttcct cgctctgctg ttgctaaaga cgcagtgttg gaacaggcac
     2941 agaaagaaca acagactaac ccgtataact tacccgcagg tacggctgcg ccgcaaactg
     3001 aagctcctgc taccaatgca cctgctacag aaactccggc accggctact gaaactcctg
     3061 ctcctgcagc agagtaattc actccgtcgt caagtaagac tttggggtaa aaccattaat
     3121 gggaaggtgc agacggatgc tgcatttctt tgatatttaa gtgcggatta cgcagattac
     3181 acggattttc aatgttccgc gtggtcagtg taatccgcac ttaacttttt cttgtaaaaa
     3241 caatctcttt gtgatagaaa caaacgagat ttaactacct ttgttggctg tataagatta
     3301 ttaactactt ttttaaatat aacaatgaca gaacatttga aacagaaatt gaatgactcc
     3361 gccgtactcc gatggagtgt tctagcattg gtcgcattta ctatgctatg cggctatttc
     3421 ctcaccgacg taatgtctcc tctaaaaccc atgcttgaga aagaactact atgggacagt
     3481 cttgattatg gtttcttcac aagtgcttac gggtggttta atgtattcct attgatgctg
     3541 atcttcggtg gtatcatttt ggataagatg ggagttcgtt tcaccggaat gggggcttgc
     3601 ttattgatgg tgtttggttg tggattgaaa tactatgcga tttctactac ttttccggaa
     3661 ggtgccatgc tcttcggatt caaaacacag gtgacgttgg ctgcattggg atatgctatc
     3721 tttggtgtag gtgtggagat tgctggtatc actgtttcca agattatagt gaaatggttc
     3781 aagggcaagg aaatggcatt ggctatggga cttgaaatgg ctacggcacg tatcggaaca
     3841 actctggcga tggtattgac agttcctttg gcagactttt tcggatctac ggatgagagt
     3901 ggcacattcc atacaaatat tcctgctccg attttgtttt gtctgattat gttgtgcgtg
     3961 ggtacgattg cttttttcct ttatactttc tatgataaga agttggatgc ttctttggat
     4021 gcagagggat tggaaccgga agaaccgttc cgtatgaaag atattgtgta tattattacc
     4081 aataaaggat tctggttgat tgcattacta tgtgtattgt tctactcggc tgtattcccc
     4141 tttatcaagt atgctgccga cttgatggtg cagaaatata acgtagatcc gaagttggcg
     4201 ggaacgattc ccggattgtt gccgattggt gcgattatcc tgactccgtt gttcggttcg
     4261 ctttatgacc gtatcggtaa gggagccaca ttgatgataa tcggatcagt gatgcttatt
     4321 tttgtgcata cgatgtttgc tctgcctata ctgaatatat ggtggtttgc tactatcatc
     4381 atgattatat tgggatttgc cttctcgttg gtgccttcag ctatgtggcc gtctgttccg
     4441 aagattattc cggaaaaaca gttgggtacc gcatacgcat tgattttctg ggtacagaac
     4501 tggggattga tgggtgttcc tttgttgatc ggatgggtgt tgaatactta ttgcaaaggt
     4561 ccggtagtag acggtgcaca gacttatgac tacacgttgc cgatgactat ttttgctctc
     4621 tttggtgtac ttgctctgat tgtggctttg atgttgaagg cagagaacaa gaagaaggga
     4681 tacggtctgg aagaggcgaa tatccaaaag taactgggaa attcaatacc taaagtaaca
     4741 aaggaatttt gtatcaaggt gtaaacaaaa gggtatcagt atgaatactc tgaaataaaa
     4801 aataagaagt atggctgcca aagagaaaat caacctgtta gaggtcattc cctgtcgcag
     4861 tgaacatatt acagcagaaa gggaagggga gacaattgtg ctctcctttc cccgttttaa
     4921 atatccgtgg atgcaacgct tccttgtgcc gaaaggaatg tcgaaagaac ttcatgtgaa
     4981 attggaagaa cacggtacgg ctgtatggga actgatagat ggaaaacgca atgttcgtga
     5041 gattatagaa aaactcgcag accattttca aaatgaagag ggctacgagt cgcgtgtatc
     5101 ggcttatctt tctcaaatgc agaaagatgg atttataaaa ctggtgatac cagtcgcata
     5161 aataggaatt tatatttcac cacagaggac acggaggaca cagagttctt ctctctcttt
     5221 ccgcaagtaa aacagagcga taaatacgat tctcaatacg tgagactctg tgttactcta
     5281 tagtgaataa aaaagattaa acctctgtgt cctccgtgtc ctctgtggtg aatttattat
     5341 tatttatttg ataaatacag cccaaagtat gacggcaatt gctatcagga ctcccatgat
     5401 aataagcgtt ccccaaacaa aataattgct gtctttctct ttctttttct ccgagtcgtg
     5461 gatgatacgt tccatttctt cgggagtggt attgggtagt ggataaggtt cgtttgcacg
     5521 gtttaaatgc ttcaacttgt cgttagcacg ttcacgacgt aggcgggaag cttcccgtcc
     5581 ctcttttatt cggcgtatca tgtcgaatgc atgtccttca ccaaccatat tctttgtttt
     5641 ttagaagttc actttctcgt ttttctattt cccttcttct ctgtccactt tgagcaatcc
     5701 tcccgtattc ggatcaaaat aaactttgat ggtagaattc ttgttgaaca aaaccggagc
     5761 cagatattct atcacaccaa attgagtaat aggaagttca ccttcgtaaa gtttcttttt
     5821 gccgtcggtc aatgtaacca tagcttgtcc gggtacgttg taggcgattc catccaaatc
     5881 tttcttcttc ttaccatctt cctgtggtat cttgaccgat ttcaggtctt tcagactgat
     5941 ataaaacgga gttcctgcca aatcattgtt ggcaactaca cctaacttct tcgagaagcg
     6001 gaaagcaact tcattgttga attccttgtc aggggtaagg cggacagtga atgttctctc
     6061 ttccttgttg caggtgccgg agaacatttg cgtcatggct tcttcctgtg cattcagatt
     6121 gtcgagcata atcttaagct gtgctccgtc tgaaggcata ttgtcagcct gtccgcgcaa
     6181 taaggcattt ttgctttcgc ggatgttata gatttcttta gccaccagtt cggccatctt
     6241 ggcggtagag ctagccatca gaatctcttc ggtcaggaat tcacgaggat ttgctttctt
     6301 ttggaggact gtgggagcgg gagcggcttt tttgcctaca ctgctgttgc tgtaaggaac
     6361 attgatcgtt ttcacaatgc catcctctgt cagttccatg agcggtgcta ctgtcttatc
     6421 cttcaatttt acgaaatacg tcgtttcgct gttgggcaca cctacggatt tcacttttac
     6481 gctagtcagt tcccagtact cttcagggtc ggcggagacg ttggtcagtc gcaggtaacg
     6541 atcagcatat ttgctgaatt ctcccggagt atagttgact ttgttggctt ttatttcaag
     6601 ttctatttgg gttttgggaa gactgtaaac cactccatag tcttttcctc gggtaacccc
     6661 tgtcagtact tcggtttgtg cataggcgga cgttgtcata agtagtcctg ctgctataat
     6721 caactttttc atattcggtt ctttttaact ggttttgaaa acaaagttaa tgaagttatt
     6781 gaaaaaactg taagttctta acttttattc gcttacaagt cgccatgctg tcggcagaca
     6841 ggtgataata tcgcttgcga tcattccgat cattccttgc ttcttttgag cgacatcgcc
     6901 cgccaatccg tgaatgtaag tgccgatttt agcggcttct tcggtgggat aaccttgggc
     6961 aagcagcgcc aggattactc cggtcagtac gtcaccgcta cctccggttg ccattcccgg
     7021 atttccggtt gggttgaaga aacatttacc ttcgggggtg atgatggcgg agtaggctcc
     7081 ttttaaaata atgtggacat gggcggcacg ggccagttcg caagccttca tcagacgttc
     7141 gtaagagtcc tggcatttgc cggtcagacg ttccagttct tttggatgcg gggtgaggat
     7201 ggaacccttc ggcagatggg taagggcatg acggtggttg gcgaggatat taagagcgtc
     7261 ggcatctact acaacaggag tcaggcagtg ttccagttgt tccaataagg cagcttccgt
     7321 ttcctcgttt cgtcccagtc ccgggccgat gccgactgct tgatagtcgt ccgtgtcggt
     7381 aggtacggca aaacaggttt cgttgatgtc ggtttctacg attgcttcgg gtatggaggt
     7441 ctgcaagatg tcgttgttgc acattggcgc atgaacagtc agcagcccta ctcccgaacg
     7501 gaggcaggcg cgggcagcga gaacagaggc tcctgccatt ccttttgaac cggcaatcaa
     7561 tagtgcatgg ccgaagttcc ccttgtgggc aaactgtttg cgtggcttga tgagtgaacg
     7621 gatttcttct atttccaaca tttcgtagtt agtctccatc tcttcaatac cgtcttcgct
     7681 taattggata tccagcactt cccattctcc gacaaattca gtgttctctg cgaaaagaaa
     7741 ggcgagcttc ggcagttgca gactgaaagt tacgtcggcg cggataatat tagcttttac
     7801 gttgaatgta ttttcttctc ccatcagtcc ggaaggaatg tcgatggcta ctaccatagc
     7861 aggggaggaa ttgatgtatt tcactacggc agcgaatccg ccgcttaacg gtttgttcag
     7921 gcctgaaccg aataatccgt cgattaccag atggtcgggc gtcagggcgg gaggtacgaa
     7981 ttgggtactg atttcgtgga attttacttc ttccatcatt tctaccagtt ctttattggt
     8041 ctggcagtcg ggtgaaagtt ctcctttcgt gttgaagaga aatacctcga ttttatatcc
     8101 tttttcagcc atcatgcggg ctacggcgag agcgtctcca ccattattcc ccggtccggc
     8161 aaagatagtg accggcgttt ccgtattcca tctgtctgtg atggcttttg ttaatacggt
     8221 tgctgcacgt tccatcagat cgattgatgt aataggttcg ttctcaatgg tataagcgtc
     8281 caatttcttg atactgctgc ttggaaatat tttcattgcg atgttctttt agttttcgga
     8341 ttacaaatgt acatgattct tctgactttt cccgtttgtt gtgggaagaa aaccataatt
     8401 gcaactttta attcatcatt agttctatct tttggtcaaa gaaatatctg cttttaaact
     8461 attaagtgtt agaataactc cgctaaaaaa taattcaatg ctgcaccatt atgaacttac
     8521 ttttatttct ccctgaaaaa gatttcttca tttcatttct catattctca ttgtttttcg
     8581 ataaacgaaa gataatcaaa tagatatctt atgagaaaca ctttttcaaa acggtatttc
     8641 tcataagttc tcccatgttt tggctcaaaa gccaccttat tctcatcgta tttcagggta
     8701 tttctcatag tcaaaagcca ttctttcttc cttttttctt tcagcctgcc ttatttttat
     8761 caggaaatga agctactatt tagataaaat agtggctttt tgcttggaga tgctcgttgt
     8821 tctcgattgt cccatatatt gtgggaaagt attctcgtat attgaaggaa aactttccca
     8881 caaaataagg gaatactttc ccaagcctta gggaatcttt tcccacaata tgtgggacta
     8941 agacactgtg tatggaagca agcaaaagga atatatagtt ctatttattc aatgtcagct
     9001 tccggcacgc tacactatga gaaatgaagc aaaatccggg ttattttgcg aagaaactat
     9061 gagaaatgcc tgttttaaaa tcatttctca tagtctatct tattagttta ctgccacttg
     9121 tgccttattt atgagaatat gagaaatgaa aatgaaaaat ctttttctgt agaggggcgg
     9181 atggaaattg tgtttagttt atctccatac cttcttaaac aaatttttaa tgcggttccc
     9241 ttgattaagc ctttgattat ttgccgtttc cgataaaaat gttatctttg gagatagata
     9301 atgtgcatca cattattttc cagtgctcac aatgaattag aatctaaata acggattgtt
     9361 taatcttcta aagtttgcat gatggaaaag acaaaaattg gcttgaatgc cgggaaagta
     9421 tggcgcatct taaatgaaaa aggtgaactt tcaatgttcg atttgtgccg tgaattaagt
     9481 ttgacgtttg aagacgtagc tcttgctatt ggttggctgg cccgagaaga caaaatcttt
     9541 ttgaggaaaa gagaaggaat gctttttgcc agtatcgaaa atgtcgaatt tacttttggc
     9601 taaggtggta gctaacctat atttaagatg gatctccact ttgttattta cacagctaaa
     9661 aaaataatga agtggatcag taggattttt tatgcccatt tttattattc cccctattat
     9721 tctgtttgat aagagaagca tctaatctac tttttctgta cctttgcacc ccataaacta
     9781 ctaaacacat aaattcatga gtgcattgaa agggcatccg aaaggccttt atctgatttt
     9841 cgcgacaagc acggcagaac gtttcagtta ttacggtatg cgtgcgatct ttattctttt
     9901 cctgacgcag gcattattgt ttgacaaaga agcggcagca tccatctacg gcagctatac
     9961 cggactagtt tatttaaccc cgttgattgg cggatacatt gccgataaat attggggaat
    10021 tcgtcgttcc gtgttttggg gagcggtgat gatggcagtc ggacaattcc tgatgtttat
    10081 gagtgcttcc actttagata atacgaacct tgcccactgg atgatgtatg gcggactagg
    10141 cttcctgatc ttgggcaatg gttgcttcaa acccactgtc tcttctctgg taggtcagct
    10201 ctacgaaccc ggagacaggc ggctggatgc tgcatacacc attttttata tgggagtgaa
    10261 tgtaggttct tttgctgctc ctttgatttg tggttatctg ggtgataccg gtgatccgca
    10321 tgactttaaa tggggatttc ttgcagccgg aatcatgaca ctgttcaccg ttgttctttt
    10381 cgagactcaa aagaataaat atcttttttc tccttccgga gaaccgattg gtattattcc
    10441 cgatgctaaa cgtgaaaaga aagaagacaa ggccgaccat atctcacacc cgaagatgga
    10501 caaacgtacc aaagtacgta atacccttgt aatcacaatt cttaccattg ctttaatagc
    10561 cttctttaac tatgcatttg aaggcgattg ggtgagtatc ggcattttta ccgcctgcat
    10621 tgttttccct gttctgatcc tgttagacgg ttcattgacc aaaatagaac gcagccgtat
    10681 tttcgttatc tatatagtag ccttctttgt catcttcttc tgggcagcct acgaacaggc
    10741 gggagcttct ttaactcttt ttgcgtccga acagacgaat cgtgacattt tcggttggga
    10801 aatgccggct tcgtggtttc aatccttcaa tcctctgttt gttgttgtcc tggcatatat
    10861 aatgccgggt gtgtggagct tcctcaacaa acgaaagatg gaacccgctt ctcctaccaa
    10921 acaagcgatt ggtttgttac tcctttcttt aggttatctt ttcatctgtt tcggagtgaa
    10981 agatgctgtt cccggagtga aagtgagcat gatttggctg acaggacttt actttattca
    11041 taccatgggt gaaattgctt tgtcgcctat cggactttca atggtaaata aattgagtcc
    11101 gctgcgtttc gcctccttga tgatgggaat ctggtatctg tctactgcca cagccaataa
    11161 atttgcggga atgttgagcg ggctctatcc ggaagccgga aaagtgaagt caatctttgg
    11221 ttatcagatt gctaccatgt atgatttctt tatggtattc gtcgtaatgt ccggtgttgc
    11281 ttcgttgatt ctgttccttc tctcgaagaa attacagaag atgatgcacg gggtagaata
    11341 aaaaatcgta tttttgcaag gttattttta aattaccggt tatggatacc attcagataa
    11401 aagacaaatt gtttaccgtt tctattaagg aacaagaaat tcagaaagaa gtgattcgcg
    11461 tagcgaacga aattaaccgc gatttagcag gtaagaatcc gcttttcctt agtgtgttga
    11521 acggttcgtt catgtttacc gctgatttac tgaagcatat caccatccct tgtgaaatct
    11581 catttgtgaa gttggcgtct tatcagggca tcacttccac cggagtgatt aaagaggtaa
    11641 tcggcctgaa tgaagacatt gccggacgta ccattgtaat cgtagaagat attgtagaca
    11701 caggactgac gatgcagcga ctgctcgaaa cattaggtac acgcaatccc gaagctatcc
    11761 atatcgcttc tctgttggtg aaacctgaaa agctcaaggt aaacctcaac attgaatatg
    11821 tagcgatgga aattccgaac gactttatcg taggttacgg actggattat gatggtttcg
    11881 gacgtaatta tcccgatatt tatacagtaa tagattaata ttaaataggt accagtttaa
    11941 atggtaaata gtaaatcgtt aaatagtaaa taacaaaatg ttgaacatcg taattttcgg
    12001 tgctccgggt tcaggaaaag gaacacagag cgaacgtatc gtagaaaagt atggaatcaa
    12061 tcacatctcg acaggagatg tattgcgtgc tgaaatcaag aatggcacag aactgggtaa
    12121 aacagctaaa ggttacatcg accaaggtca attgattcct gatgaattaa tgattgatat
    12181 tctggcaagc gtattcgaca gcttcaaaga tagcaaaggg gtaattttcg acggtttccc
    12241 aagaacaatt gcacaggcag aagctttaaa gaaaatgttg gcagaaagag gacaggacgt
    12301 ttctgtaatg gttgacttgg atgttccgga agaagaactg atggtacgtc tcattaaacg
    12361 tggcaaggat tccggtcgtg ctgatgataa cgaagaaaca atcaagaaac gtctgcatgt
    12421 atatcattca cagactgctc cactgatcga ctggtacaag aacgaaaaga aataccaaca
    12481 tatcaacggc ttgggtacta tggaaggtat cttcgctgaa atctgcgaag cagtagataa
    12541 attgtaataa tacaatatta taaataaata agtcagtagc cggagtgttc taattaactg
    12601 ctctaactac tgactacttt aactctttaa aaaaatatgg ctgaatcgaa ttttgttgat
    12661 tacgtaaaga tatactgtcg ctcgggtaag ggcggaagag gctctacgca catgaggcgc
    12721 gagaaatatt gtcctaacgg aggtcctgac gggggcgatg gtggaagagg aggtcatatc
    12781 atcttgcgcg gtaaccgtaa ttactggaca ttgctgcact tgaagtatga ccgtcatgca
    12841 atggccggtc atggtgaatc ggggagcaaa ggacgtagct tcggaaaaga cggtgcggat
    12901 aaaataatag aagtgccctg cggaacggta gtttataatg ccgagacagg ggagtatctt
    12961 tgtgacgtaa cagaagacgg acaggaagtg atcttgctca aaggcggtcg cggcggtcag
    13021 ggtaactggc atttcaagac ggccacccgt caggctccgc gttttgcgca gccgggagag
    13081 ccgatgcagg aaatgaccgt tatcatggag ctgaaactgc ttgccgatgt cggtctggta
    13141 ggtttcccga atgcgggaaa gtcaactttg ctttcttcca tttcggctgc taaaccgaaa
    13201 attgccgatt acccgtttac tacgctcgaa cccaacttgg gcatcgtttc ctatcacggt
    13261 ggaaaatcct ttgtgatggc ggacataccg ggtattatcg aaggtgccag ccagggaaaa
    13321 ggtttgggac tgcgtttctt gcgtcatatc gagcgtaatt cattactgct gtttatggtt
    13381 ccggcagaca gcgacgacat tcgtaaggaa tacgaagtct tgctgaacga actgcgtact
    13441 ttcaatcctg aaatgttgga caagcaacgt gtgttggctg tcaccaagag cgatatgctc
    13501 gatcaggaat tgatggacga aatagaacct acattgccgg aaggcattcc ccacgtattc
    13561 atatcttctg tttccggttt gggtatctcg gtgttgaaag acattctttg ggaagaactg
    13621 aataaggaaa gcaataagat agaggacatc gttcaccgtc cgaaggacgt aacccgtctg
    13681 caacaggagc tcaaagacat gggcgaagat gaagacatcg tttatgaata tgatgacaat
    13741 gttgatgatg atgacgatga tatcgactat gaatacgagg aagaagattg ggaagaaaaa
    13801 tgatttcact tacaaaaaat aatgagttga agggatataa gtcactggat gtatatcctg
    13861 aggtagctca tttcgtaaca acgcgtcacg aaggtataag caccggagct tacggctctt
    13921 tcaactgttc gccttatacc aacgactcat gcatgaacgt caatcgcaat cagagctggt
    13981 tgtttcagtg catgaatcat cagataaagg agttgtttat tcctgaacag agccatggtt
    14041 gtgccagtct gattatcaat gaatcatttt ttaaagagtc attagaaatg agacggctac
    14101 ttttgcgagg aatggatgcc ttgataacta atgtgccggg gtattgcgtt tgcgtcacga
    14161 cggcggattg tgttcctgta ttgctgtacg acaaaaaaca acacgttgtg gctgccgttc
    14221 atgccggatg gaaaggaact gtgaagcata ttgtcagtca tgtgatggat cacttgaatc
    14281 agaaattcgg gacgcaaggc gaagatgtgg tagcttgcat cgggccgagc atttcgctcg
    14341 aatcatttga agtaggtgat gaggtgtatg atgcttttaa agaaagcggt ttcgatatgt
    14401 ctcttatttc tatgaagaag aaggagacgg gcaaatatca tattgatttg tgggaagcca
    14461 accggattga attactgaat gccggagtgc ctgcagaaca gatagaagta gctggcatct
    14521 gtacctatat tcatcatgat gaattcttct ccgcacgtag actgggaata gattccggtc
    14581 gtatcttgtc gggaataatg attagaaagt aataattggt gtccgtaatt gcaggacgct
    14641 gatgattggt ttatgataag ttatgtttga aataaaagta tctaaagaaa taaaagacgc
    14701 atgcccggtt ttcgccggag ccgccgtgta tgctgcagtg aagaatactg cttacagcga
    14761 aggtctttgg cgtgaaatca atgctttcac cgaacaactg acttccacta cacagatgga
    14821 agacatcaaa catcaacctg ttatctttgc tacccgtgag gcttataaac gttgtggcaa
    14881 agaccccgga cgttatcgtc cgtcagccga agctttgcgt cgccgcctga tgcgcggaat
    14941 ccctttatat cagattgata cactggtaga cctgattaac ctcgtgtctc ttcgtacggg
    15001 acattctatt ggtggtttcg atgcggataa aatacaaggt acacaccttg aactcggtat
    15061 cggcaaagct ggagaaccgt ttgaaggtat cggtcgcggt gtgttgaata ttgaaggatt
    15121 acccgtatat cgcgattcat tcggaggaat cggaacaccg a
//
