LOCUS       gnlProkkaAKNPCAJD_130  12306 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AKNPCAJD_130.
ACCESSION   gnlProkkaAKNPCAJD_130
VERSION     gnlProkkaAKNPCAJD_130
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 09:25:19
            Original ID  :: gnl|Prokka|AKNPCAJD_130
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12306
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12306
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4759:6394]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4760..6394
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12306
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12306
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             162..440
                     /locus_tag="ctg83_1"
                     /transl_table=11
                     /translation="MQEHFGNTMNLARIKLMTYVINTFCIVQTVSLHKLVATIPTTVKR
                     DSNMRRFQLFFAKYALNLYLIARMIFRMLTRLKAVVLAFPAVSSIHV"
     CDS             complement(350..619)
                     /locus_tag="ctg83_2"
                     /transl_table=11
                     /translation="MALFKEQLESYKEKIGKGKAESTYCGLVADYKSLLLFMKTKKNIE
                     DIAIDELEKTFIEDCYTWMLETAGKANTTAFNRVNILKIILAIR"
     CDS             complement(746..943)
                     /locus_tag="ctg83_3"
                     /transl_table=11
                     /translation="MRSILKVLFYTEKAVCKNDKAPVMGHITINGTQAGFSCKKEVSFT
                     LCDVKINWAKGKSEEAPTLN"
     CDS             1504..2037
                     /locus_tag="ctg83_4"
                     /transl_table=11
                     /translation="MVKTRVVNIRKETCDVYIGRAGHGKDGYFGNPFRLEVTMARGSTL
                     DRYRKYFYHRLGTDDEFRKRIGKLQGKTLGCFCKPNPCHGDIIKEYLDRLAENADEVVI
                     GKIHWKGCSYPVREIDTDNRTFRVSVESLRDEMINDIRNGIYETMEACEEIDGYCTDEE
                     LCTLSDVELYKMYC"
     CDS             2087..2326
                     /locus_tag="ctg83_5"
                     /transl_table=11
                     /translation="MERFHEILIGHGLDATNVGINHIRIFLDGKKLFDYYPLKMKLFDY
                     HNWHQLTYPSFLEGVDKWETELDGIIKKLMVSPQ"
     CDS             complement(2586..4763)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 283.3; E-value:
                     6.5e-86)"
                     /gene_kind="transport"
                     /locus_tag="ctg83_6"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.3e-36, bitscore:
                     115.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRVSYQHDSMQCGAACLRMVCKHYGKEYALDFLSEQCGCMIDG
                     VSLQAIRETAEDLGFRTFAVSVGLSELQAGWCPCILHWERNHFVVLYRIHKDKYHVADP
                     AKGTVIYRKEDFLKRWAGDGEQGIALLLEPTQAFYDFSSGMEPKVPSPFRFLWRYIASY
                     KKAFASVALTLLVGSLVQLVLPLLAQMMVDKGIGHKNIPLVYLILGGQLVLVLGSAAME
                     FVRNRLLLFVGMHVNISLITDFFAKLFRLPISFFETRTTGDLLQRIVDHRRVQDFLTGQ
                     VLSVLFSVMVLCIFMGVLFSYNSFLFLVFLAGSIGYGLWTMCFLHKRKLFDYMIFEKQS
                     ASNNKVYQLLTFMQEIKLQGGEGRRAGEWEALQKELLDIQMRSLSLQQFQQTGGIFISQ
                     SKNLVVTVIAAVSVIEGEMTLGMLLAVQFIIGQLNIPIEQLMQFLYNFQNVRLSIERIS
                     AIHGKAEERTGKEIPEQPEISRKDIRIEHLDFKYNLHGKAKVLDDITLTIPAQRTTAIV
                     GASGSGKTTLVKLLLGYFAPTSGNIFLGDTPLQDYDMTSWRHSCGVVLQDSHVFSESLA
                     RNIAVEDKHIDRTRLRTAARQANLEEFIEKLPLKYQTMVGAEGVGLSRGQEQRIFIARA
                     LYKDPSFVFLDEATNSLDANNERIITGNLLDFCKGRTVLIVAHRLSTIRHADKIVVLHK
                     GRIVEEGTHDELCARHGYYYELINNQLIAMG"
     CDS             complement(4760..6394)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg83_7"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     6.4e-22, bitscore: 68.1, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKTNKFPLVKLFTVDGASCYLYDGRANMFLSLSETEKNLVCE
                     YMASYGTSEGEPCPASFPSGAAAFIARLNGNGILLPGPLEARTPSGMRGEEQLWQQWEE
                     EAIPKKLTLEMTNTCNLRCRYCPYTINEQRGQGKMHASHHLKEEDARKAISDYFHEYTR
                     VFRKVEPEHRTLFLKRNPPAVSFYGGEALLRFSLLEPLVKYVLSLPWEEHHIPAEKVVF
                     HITTNATLLTREMVEFFIRYHFTLAISFDGPPEENDKYRVFKNGQGTGTVVERALDMIH
                     EVSEEYLLNHVHIQAVLAPEYDHDKVGRYFEGRSLNGCYGGVRQFSYLEFSDYSESKKT
                     DKQLAQFNIRERIKELYEKGLSPEERYQYILRDPLISAWLRYVYAILTKVGDAPSHKAR
                     YFNSCYIGRTNLLLDTYGNLHLCERSDFSMPVGEVNSGINRTAVRQMYRDFFEKTDSPS
                     CRSCWAGRFCTLCTAALIKNGAVQEPDRSICRSLRHAQEKQIEDLLYIKEYYPEILEQM
                     ERMYFQANDITLGAFHAYVKEQQDVAP"
     CDS             complement(6435..6629)
                     /locus_tag="ctg83_8"
                     /transl_table=11
                     /translation="MGKQIAKLGIRPEDLKDKTVTSEQLEKTKGGKAAGSEECVCYCGC
                     YTDDSAFGVDFNWWSRDWD"
     CDS             complement(7051..7716)
                     /locus_tag="ctg83_9"
                     /transl_table=11
                     /translation="MEEIVYLSVRIGCAGYLLYKLWNQKKRIRKICGLLYPPGKKEKEE
                     EGTSCGTGSGDVMGATRFVYLDENAGTFAAPYMSQPLETGNDYLGEEEAVPENEVECGL
                     PLEEMRLLKEEQERLDEQAPGTEGIAPVITSDDLLNAGDVLLNLDGAQMDEEKKRRAAV
                     TLHAIRETDMFELISSQVENKSLIEELIDQYIGNDGNVLPVKRKKKEGQPEHAWRQFL"
     CDS             complement(7704..8156)
                     /locus_tag="ctg83_10"
                     /transl_table=11
                     /translation="MATKRRTDYQVDEEALKRMMAGDVTALDKMASPAEAPETKSRPAP
                     SQEKQEKNFAGSPKQQIRKSTDEASGPDEYRRRFLKERLSGSRRQTYIHDALYRTVAKL
                     LPVIAPDMSVPMFLGSVLSDHLERYQDVINEIYNQEANQNPLEWKK"
     CDS             complement(8165..8926)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 76.9; E-value: 3.1e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg83_11"
                     /transl_table=11
                     /translation="MKKEPLFVALSNQKGGVGKSTFTVLLASYFHYLKGYNVLVVDCDY
                     PQHSISTMRDWEVGTIEKNVHLQNQLVEQFGTSGRKVYSILNSTPEEARETAGRFLEKS
                     ELDYDLVLFDLPGTVNVPGVFRSVINMDYVFTPVTQERMVMRSSMAFVLAIREYMHRHK
                     DVPLRGIYMFWNRMDKRVSKDLYNSYTEIFRSLKLPAMETVIPSAERYNKDFGMKGFFF
                     RSTLFPPTPSALRGSNLDLLATEIETILKLQ"
     CDS             9463..9735
                     /locus_tag="ctg83_12"
                     /transl_table=11
                     /translation="MERNTLRRTTARRERRAAIRRRRILCSNEQSKLCPCPTKSLLSDK
                     DQLARPGRGNPLQSRGFWKRKKVQTNNLMHYGENNRDKDRQETQE"
     CDS             9689..10111
                     /locus_tag="ctg83_13"
                     /transl_table=11
                     /translation="MEKTTGTRTGRKPKNDPADRKYSFRLNAEENTRFERLLADSGARD
                     RTLFIKKSIFSGQIKVVRIDKATMDYYIKLTEFHKQFQAIGNNYNQVVRALKNNFGEKR
                     AMSLLYRLEKLSVELMLLCKKITALTQEYERKWLQR"
     CDS             10096..11352
                     /locus_tag="ctg83_14"
                     /transl_table=11
                     /translation="MVAKISHGASLYGALAYNHNKVATGAAGILSGNRMISDRLGLPSE
                     DIRLALLSFENYLLANRNTEKPVLHISLSPAPEDRLTDDQLAELADRYMRKMGYGDQPY
                     IAYKHADTHNAHIHIVSVCVDEQGKKISDSYEHRRSMTACRELEADFGLRNGADTEERN
                     PKAELKKVDASLGDVRHQIGNTLKAVLESYRFQTFGEYSALLSTLNIEAKQVRGEYHGV
                     PYTGIVYAATDDAGKVVSPPFKSSRFGKRFGNEQLEKRMLLNLKALKEGKWAPSIQADI
                     ARALQQADSRQRFVEQLGQKRIGVVFRENEQGRIYGVTFIDHDRREVFNGSRMGKEFSA
                     NVFNDYFRWLDGIPENDRNGHTATELWQHHRHKAGPESALEQAAGILSLETNPRDYEEE
                     AFARRMKKRKKAKRKSRGI"
     CDS             11392..12306
                     /locus_tag="ctg83_15"
                     /transl_table=11
                     /translation="MQQEDDLRALAKIMEFGRAVSIFLLVVHVYVYCYPSITAWNLNLE
                     VTDRILVNFNNTTGIFNCILWTKLLAVTLLAISCLGTHGVKGEKITWPKIYAALVAGCV
                     LFFLNWWLLDLSLPHMTSTILYVVTLTAGYLGLLMAGLWMSRLYRHNLMGDVFNIENES
                     FQQETRLLENEYSVNLPTSFRFQGKQHDGWINVVNPFRATIVLGTPGSGKSYAVVNNYI
                     RQMISKGYSCYIYDYKFDDLSTIAYNTLLNNMDKYKVKPRFYVINFDDPRRSHRCNPIN
                     PEFMTDISDAYEASYTIMLNLNRT"
ORIGIN
        1 tgacaaaaat tgaaattatt atttctaaat atccaaatct caaatagttt tttctaatta
       61 ttgatatcta gcaatttaaa agaaaagttt gtcgactttt ctccataaga actactaaaa
      121 gatccaagga cttagtcaaa gttaaccaaa ttcttccgat tatgcaagag catttcggaa
      181 atacaatgaa tctggcacgc ataaagttga tgacatacgt aatcaatacc ttttgcattg
      241 tccagactgt cagtcttcat aagttggtcg caaccatacc tacaaccgtg aaacgggatt
      301 ccaatatgcg aaggtttcaa ctcttttttg caaaatacgc cctcaatctt taccttatag
      361 caaggatgat tttcaggatg ttgacacggt tgaaggctgt ggtgttagct tttcctgccg
      421 tttcgagcat ccatgtatag cagtcctcaa tgaacgtttt ttcaagttca tcaatagcta
      481 tatcttcaat gttctttttg gttttcatga aaagcaaaag gcttttgtag tcagcaacca
      541 gtccacagta ggtgctttcc gcttttcctt tacctatctt ttccttatac gattcaagtt
      601 gttctttgaa aagtgccata agcgtgtgat agtcttcacc aaaaccaacg taacggttat
      661 agactttctt ggctgtaacg aaaccatcat ggtcgcaaat atactgatag tgcttggcaa
      721 tttgcgcctt gatattatca agttcctaat taagagtagg ggcttcttcg gatttacctt
      781 ttgcccagtt gattttaaca tcgcacaacg taaaggatac ttctttctta caactgaaac
      841 ctgcctgagt tccattgatg gtgatatgcc ccataacagg tgccttatcg tttttacaaa
      901 ctgctttttc tgtgtaaaat aacactttta atatacttct cataactcaa ctttttttgt
      961 tacaaattta ttgaaaatca gtacactgta ttcattttag gggattttgg aggtgagtta
     1021 cgatttggta acgtaactcc ctccaaaata tgctttcctt tgctttcttt ccccatcctc
     1081 gctaaaaaat acaaaaatat attttataac tatttgattt tttagtatgg ttgcgttgtt
     1141 tttgtgtgcc tttttgaaac actaagtttc acaataatag aacaactgac tttcaggata
     1201 ttgtggatta ataaaacgta ttaaaatgaa cctgatttac gacacctgat tccgcaggaa
     1261 gaaagtgata agaaataaaa tcagacagac cgctttttta tttcagcctg caaagttcgt
     1321 cccgtgcctg tcaggattga gcaaggccgg gcccttgcgg gtttccgaaa aaatcttccg
     1381 cgctccgctt gcggtatttt cccggaaagc cttgcacaat ccggcacgga acggtatagc
     1441 aggcaggaaa taaaatatcg gctcacgaac cggtgaaatg tttaacagaa taaaaagatg
     1501 attatggtca aaacaagagt tgtaaatatc cgcaaggaaa cttgtgacgt gtacataggc
     1561 agagcaggac atggtaagga tggttatttc ggaaatccgt tcaggttgga agtaacaatg
     1621 gcaagaggca gcacgcttga ccgttacagg aaatattttt atcatcgtct gggtacggat
     1681 gacgagttcc gcaaacggat cgggaaattg caaggcaaga cattgggatg tttctgcaag
     1741 ccgaatcctt gccacggaga cattattaaa gaatatctgg accggctggc tgaaaatgca
     1801 gatgaagtag tcattggaaa gattcattgg aaaggatgtt cttatcccgt cagagaaata
     1861 gatactgaca accgtacatt cagggtatca gtggagagcc tgcgggacga aatgataaac
     1921 gatatacgta acggcatata tgagacaatg gaagcgtgcg aagagattga cggttactgt
     1981 accgatgaag aattgtgtac gctatcggat gtcgaattgt ataaaatgta ttgttaaaac
     2041 aaattgcaat aaaggaatta tgaaaaaaag aagcaacttc acaccaatgg aaagattcca
     2101 tgagattctt atcgggcatg gtctggacgc gacgaacgtg gggattaacc atatccgcat
     2161 tttcttggat ggtaaaaaac tcttcgacta ctatcctctg aaaatgaaac tgttcgatta
     2221 ccacaactgg caccaactaa cttatccgtc ttttctcgaa ggtgtggaca aatgggaaac
     2281 ggaacttgac ggaatcatta aaaaattaat ggtatcaccg caataagtat tccggttacg
     2341 aaggaaaaca ataacacaac gctcgtttgg gacaacattc ctgaatgagc gttttttcat
     2401 tggtcaagtg taatgagaag ccagaagtag cactctaagg gttgatgcaa ctggttccat
     2461 tatataatag agattgtttt ttagatatag tttatactct attgtcaaaa tacggaaaac
     2521 aaagaaaaaa gcaagacctt gacgaaaagg cttttttgac atataaaagt taaaaaatac
     2581 tatcttcacc ccatagcaat caactggtta ttaatcaact cataataata cccatggcgg
     2641 gcgcacaatt cgtcatgggt accctcttcg acaatcctgc ctttatgcag aacgactatc
     2701 ttgtcagcat gacggatggt gcttaaccgg tgggccacta tcaggaccgt ccttcctttg
     2761 cagaaatcca gcagattccc ggtaatgatt ctttcattgt tggcatccag cgagttggta
     2821 gcctcatcaa gaaacacgaa cgaagggtcc ttatagagcg cacgggcgat aaagatacgc
     2881 tgttcctgtc cccggctcag ccccacgcct tcagccccca ccatcgtctg gtatttcaag
     2941 ggcagtttct ctatgaactc ttccaggttg gcctgacggg cggcggtccg gagacgtgta
     3001 cggtctatat gcttgtcctc cactgctata ttccttgcca gagattcgga aaacacatgg
     3061 ctgtcttgca gcactacgcc gcagctgtgc ctccacgatg tcatatcata atcctgcaag
     3121 ggagtgtccc ccagaaagat atttccgctt gtaggagcaa aatagcccag caacagtttg
     3181 acaagggtgg tctttccgct tccgcttgcg cccacgatgg cggtggtacg ttgcgccgga
     3241 atggtcagcg ttatgtcatc cagcaccttg gctttgccat gcaggttata tttaaaatcc
     3301 aggtgttcaa tccggatatc ctttcgggaa atctccggct gttccggtat ctctttcccc
     3361 gttctttcct ccgccttccc atgaatcgcg ctgatacgct cgatgcttag ccgcacattc
     3421 tggaaattat agagaaactg catcagctgt tcaatcggga tgttcaactg cccgataatg
     3481 aattgcacgg caagcagcat acccaaagtc atctcccctt caatgacaga aacggcggca
     3541 atgaccgtca caaccaggtt cttggactgg ctgataaata tcccgcccgt ctgctggaac
     3601 tgttgcaggc tcaaagacct catctggatg tcaagaagct ccttttgcaa cgcctcccat
     3661 tccccggcgc gccttccctc gccgccttgc agctttatct cctgcatgaa agtaaggagc
     3721 tggtatacct tgttgttgct ggccgactgt ttctcgaaaa tcatatagtc aaacaacttg
     3781 cgtttatgca ggaaacacat ggtccacagg ccgtagccga tacttcccgc cagaaagaca
     3841 aggaacagga agctgttata tgaaaacagg acgcccatga atatgcacaa gaccattacc
     3901 gagaacaaga cggagagaac ctgtccggta agaaaatcct gcaccctgcg gtgatcgacg
     3961 atacgctgca aaagatcccc ggtggtcctt gtctcgaaga atgaaatcgg caggcggaac
     4021 agtttggcga agaagtcggt tatcaatgat atattgacat gcatccccac aaacagcaga
     4081 agacggttgc ggacaaactc catggcggca gaaccaagca caagcaccag ctggccgccg
     4141 agaatcagat agacaagcgg gatattttta tgaccgatac ctttgtcgac catcatttgc
     4201 gcaagcagcg gaagcaccag ctgtacgaga ctgccgacaa gcagggtcaa ggcgaccgat
     4261 gcaaatgctt ttttataaga agctatgtac ctccataaaa aacggaaagg ggacgggact
     4321 tttggttcca tgcccgaaga gaagtcataa aaagcctgtg tgggttcaag caacaaggcg
     4381 attccctgtt ccccgtctcc cgcccaacgc ttcaggaaat cttctttccg gtatatgacc
     4441 gtccctttgg ccggatcggc aacatgatac ttatccttat gaatcctgta caggacgaca
     4501 aagtgattac gctcccaatg aaggatacag ggacaccatc cggcctgcaa ttcggacaga
     4561 ccgaccgata cggcgaatgt ccggaatccc aggtcctccg ccgtctcgcg gatggcctgc
     4621 aaggaaaccc cgtcaatcat gcagccgcat tgctcggaaa ggaagtcaag ggcatattcc
     4681 tttccgtaat gcttgcagac catacggaga cacgccgcac cgcactgcat ggagtcatgc
     4741 tggtaggaca ccctgaacct catggggcga cgtcttgttg ttccttgacg taggcatgga
     4801 aagcgccgag cgttatgtca ttcgcctgga aatacatacg ttccatctgt tccagaattt
     4861 ccggataata ctccttgata tacagcaagt cctctatctg tttctcctgt gcgtgccgca
     4921 agctcctgca aatggaacgg tcaggttcct gaaccgcacc gttcttgata agcgcggcgg
     4981 tgcagagggt acagaagcgg ccggcccagc aggaacggca ggacgggctg tctgtcttct
     5041 caaaaaaatc acggtacatt tgccggacgg cggtacggtt gatgcccgag ttcacctcac
     5101 cgacaggcat ggagaaatcc gaccgttcgc agagatgcag gttgccgtat gtgtcaagca
     5161 acagattggt acgcccgata tagcatgaat tgaaatatct ggctttgtgt gagggtgcgt
     5221 caccgacctt ggtcagaatg gcgtacacat accgcagcca tgcgctgatc agagggtcac
     5281 gaagaatata ctggtaccgt tcctccggag agaggccctt ttcataaagt tccttgatcc
     5341 gctcccggat attgaactgc gccagttgct tgtccgtctt cttgctttca ctgtaatcgc
     5401 tgaattccag gtaggaaaac tggcggaccc cgccataaca accgttcagg ctacgcccct
     5461 caaagtatct gccgaccttg tcatggtcat attcgggggc cagcacggcc tgtatgtgta
     5521 catggttcag caggtactct tccgaaacct catggatcat gtcaagggca cgctccacga
     5581 ccgttcccgt accctgcccg tttttgaaca cgcggtactt gtcattctcc tccggcggac
     5641 cgtcgaagct gatggcgagg gtgaaatgat accgtataaa gaattccacc atctcccgtg
     5701 tcagcagcgt ggcattggtc gttatgtgga atacgacctt ctccgcaggt atatggtgtt
     5761 cctcccaagg aagcgagagc acatatttca ccaacggttc cagcagggaa aaacgcagaa
     5821 gcgcctctcc gccgtagaaa ctgacggcgg gaggattccg tttcaggaac agcgtcctgt
     5881 gttccggttc caccttgcgg aaaacacgtg tgtattcatg gaaataatcc gaaatggctt
     5941 tccgggcatc ctcctctttc aagtgatggg aggcgtgcat ttttccttgt ccgcgttgct
     6001 cgttgattgt ataggggcaa tacctgcaac gcagattgca ggtattggtc atctccagtg
     6061 tcagtttttt gggaatggct tcctcctccc attgttgcca taactgttcc tcaccacgca
     6121 ttcctgaagg tgtcctcgct tccaggggac ccggaagcag gatgccgttt ccgttaagac
     6181 gggcgatgaa agcggcggca ccggaaggga aggaggccgg gcaaggctct ccttcagaag
     6241 ttccatacga cgccatgtat tcacagacaa ggttcttctc agtctcggac agcgacagga
     6301 acatgttcgc tctgccgtca tataaataac aggacgcccc gtcaactgtg aacaatttga
     6361 ccaggggaaa cttattcgtt ttttgttttt ccatagtggc taatctgttt acaaagcatc
     6421 gtacaatgca ggaatcaatc ccagtctctt gaccaccagt tgaaatctac accgaaagcg
     6481 gagtcatcgg tatagcaacc gcagtagcat acacactctt cagacccggc ggctttcccg
     6541 cctttcgtct tttccaactg ttccgaagtg accgtcttgt ctttcaggtc ttccggacgg
     6601 atacctagtt tggcaatctg ttttcccata gcctttaaaa ttggagttag ttcatacttg
     6661 caacatttca ctcctttaaa atattgcaat gccgatatag cttaccggtt attcaaatcc
     6721 catagccgcg atactgacat tcgtttttcc tgataaatca cggctctata attcattttt
     6781 gaaatctgtc tcaaatatac agattccatt caaaaacaca atatttttct tagaaaaaga
     6841 taggataaac gtaatgaatt atttttcatt aacatcttag cttctatttg attccggaaa
     6901 ggaatccgtt accaaccgaa taattaaaat atatggacat ttaaagagcc atgtatgaca
     6961 aaggaaccgg gaacaggcaa ccatgatagc ggtacaaggc aggtgcttcc aaagcctctt
     7021 cctttcgtat cggactgatt gccgccgggt tcagagaaac tgtctccagg catgttccgg
     7081 ctgtccttcc tttttctttc ttttcaccgg caatacattt ccgtcattgc cgatatattg
     7141 gtctatcagc tcctcaatca ggcttttatt ctccacctgg gatgaaatca gttcaaacat
     7201 atccgtttcc cggatggcat gcaaggtgac ggcagcccgg cgttttttct cctcgtccat
     7261 ttgggcgcca tccagattaa gcagcacatc gccggcattg agcaggtcat cggacgtgat
     7321 taccggagcg ataccttccg tgccgggagc ctgttcgtcc agcctttcct gttcctcttt
     7381 caacagtctc atctcttcca ggggaagccc gcactccacc tcattctccg gcaccgcctc
     7441 ttcctctccg agataatcgt tcccggtttc caacggctgg ctcatgtagg gggcggcaaa
     7501 cgtacccgcg ttttcgtcca gatagacaaa tcgggtagcc cccatcacat cacccgatcc
     7561 tgtaccgcac gatgttccct cttcctcctt ctcctttttc ccggggggat agagtagccc
     7621 gcaaatctta cggatccgtt ttttctgatt ccataacttg tataacaagt agccggcaca
     7681 gccgatcctt actgacaaat aaactatttc ttccattcca aagggttttg atttgcttcc
     7741 tggttatata tttcattgat aacatcctga tatctttcca ggtggtccga caggacactg
     7801 cctaaaaaca tgggaactga catatccggt gcaatgacag gcaataattt ggcaacagtc
     7861 ctgtacaaag catcgtgaat ataggtctgc cttcttgaac cggacagcct ctctttcaga
     7921 aaccgtcgcc ggtattcatc cgggccggac gcctcatccg tggattttct tatctgctgt
     7981 ttgggagaac cggcgaagtt cttctcctgc ttctcttggg aaggggcagg ccggcttttt
     8041 gtttccggag cctcagcggg agaagccatt ttgtccaatg ctgttacatc cccggccatc
     8101 atacgtttca atgcctcctc atccacctgg taatccgttc ttcttttggt agccatgatt
     8161 gttcttattg aagtttcagt atggtttcta tctctgttgc cagcaagtcc agattgctgc
     8221 ccctcaatgc ggaaggggtt ggagggaaca aggtgctgcg aaagaaaaat cccttcatcc
     8281 cgaagtcttt attgtagcgc tccgcactgg gaatgacggt ttccatcgcc ggcaatttta
     8341 gcgagcggaa aatttcagtg tagctgttat acaggtcttt ggacacacgt ttgtccatcc
     8401 ggttccagaa catatagatg ccacgcaagg gcacatcctt atgacggtgc atgtattccc
     8461 ggatggcaag gacgaaagcc atgctgctcc gcataaccat tctctcctgt gtgacgggag
     8521 tgaatacata gtccatattg attacggacc ggaagacacc gggcacattc acagttccgg
     8581 ggaggtcaaa aaggacaagg tcatagtcca gttccgattt ttcaaggaaa cggccggcag
     8641 tttcccgggc ttcctccgga gtggagttca ggatgctgta gactttcctt ccgcttgtcc
     8701 cgaactgttc caccagctgg ttttgcagat gcacgttctt ttcaatggtc cccacttccc
     8761 agtcccgcat ggtgctgata ctgtgctgcg gataatcgca atccaccaca agcacgttat
     8821 atcccttcag ataatggaag taactggcga gcaaaacggt gaacgtggat tttcccacac
     8881 cgcccttctg gttgctcaaa gcgacaaata aaggttcctt cttcataggc ttgaatttag
     8941 agtgtataat ttggtttcat atctgtccgg atatgttttt tctgtttcat tacatgacaa
     9001 tgcatctgtc ggtatatggc aatgatgcac tgcctgcccg cttgcatgaa tacattgcgt
     9061 accctattgc accaatgtat tgccggttac cggagggtat tgccatataa ggtacattgc
     9121 attcatgtaa tacggagtcc aatgtaaccc gtactgtatt gcattcatgc aatgtaaccc
     9181 gccatgcagg atcaccgtgc aacatgtatg gcaatgtacc tacagggatg atattgcatc
     9241 cgtgccatgt accgcctgtg gcaggcaagc aatacacctt acaggacaat gttccaatgt
     9301 atgccctcat gcactgtgcc aaaagtaacg gctatttttg agacttccgc caacatttcc
     9361 ccggcctgac atcagatgtc gtcagatgtc atcaaacgtc atataaaacg ctatttacca
     9421 accggttaac actatctaat tttgcaaaat caaaatccgt caatggagag gaacactctt
     9481 cgtcggacca cagcacgccg tgaacgtcgc gcagcaatcc gacgaaggag gattctctgt
     9541 tcaaacgaac agagcaagtt gtgtccttgt ccgacaaaaa gtcttttgtc cgacaaggac
     9601 caacttgccc gccccgggcg ggggaatccg ctccaaagtc gcggattctg gaaaagaaaa
     9661 aaagtacaaa ccaacaatct catgcattat ggagaaaaca acagggacaa ggacaggcag
     9721 gaaacccaag aatgacccgg cggaccgcaa gtacagcttc cgcctgaacg ccgaggagaa
     9781 caccagattt gaaaggctgc tggcggattc cggagccagg gaccgcacgc tgttcatcaa
     9841 gaaatccatc ttttcgggac agataaaggt agtgagaatc gacaaggcga ccatggatta
     9901 ctacatcaag ctgaccgaat tccacaagca gttccaggcc ataggcaaca actacaacca
     9961 ggtggtgcgt gccttgaaga acaatttcgg agagaaacgg gcgatgtcac tgctctacag
    10021 gctggagaag ctgagcgtcg agctgatgct tctctgcaag aaaatcacgg cactcaccca
    10081 ggaatacgag cggaaatggt tgcaaagata agtcatggcg ccagcctgta cggggcactg
    10141 gcctacaacc ataacaaggt ggcgaccggg gcggcgggga ttctttcggg gaaccgcatg
    10201 atttccgacc ggctgggatt gccaagcgaa gacatacgtc tggcattgct ctctttcgag
    10261 aactacctgc tggcaaaccg caacacggag aagcccgtcc tgcatatctc gctctccccg
    10321 gcaccggaag acaggctgac cgacgaccaa ctggcggaac tggccgaccg gtatatgcgg
    10381 aagatgggct atggagacca gccttatatc gcctacaaac atgccgacac ccacaatgcc
    10441 cacatccata tcgtcagtgt ctgcgtggac gagcaaggga aaaaaatcag tgactcctac
    10501 gagcaccgcc gttccatgac cgcctgtcgg gagctggaag cggacttcgg cctgcgcaac
    10561 ggtgcggaca cggaggaacg gaatccaaaa gcggaactga aaaaagtgga tgcttccctg
    10621 ggggatgtcc gccatcagat cggcaacacc ctcaaggcgg tgctggaaag ctaccgtttc
    10681 cagaccttcg gggagtatag cgccctgctt tccactctca atatcgaggc gaaacaggtc
    10741 aggggggaat accacggcgt gccttacacc ggcattgtct atgcggccac ggatgatgcc
    10801 ggcaaggtgg tcagccctcc gttcaagagc tcccgctttg gaaaacgttt tggcaacgaa
    10861 cagctggaaa aacggatgct tctcaacctg aaggcgctca aggaagggaa atgggctccc
    10921 tccatacagg cggacattgc ccgcgccttg caacaggctg actcacggca acggtttgtg
    10981 gaacagctcg gacagaaacg tatcggcgtg gtgttccggg agaatgagca gggacgcatc
    11041 tacggcgtca ccttcattga ccacgaccgc agggaggtgt tcaacggctc acgcatgggc
    11101 aaggagtttt ccgcaaacgt gttcaacgac tatttcaggt ggctggacgg catccctgaa
    11161 aacgaccgga acggacatac ggcaacggaa ctctggcagc atcaccggca caaggcgggc
    11221 ccggaaagcg cgctcgagca ggcggcgggt atcctctccc tggaaaccaa cccaagggat
    11281 tacgaggagg aggctttcgc acgccgtatg aaaaagagga agaaagccaa acgcaaatcg
    11341 cgcggcattt aaacggaaga caattttcaa aaaccattta tccccatccc tatgcaacag
    11401 gaagacgatt tgagggcact tgccaaaatc atggaatttg gcagggcagt gagcattttt
    11461 cttttggtgg tgcacgtcta tgtgtactgt tatccgagta tcaccgcatg gaacctgaac
    11521 ctggaggtga cagaccggat tctggtgaat ttcaacaaca cgaccggcat tttcaactgc
    11581 atcctctgga ccaagctgct ggctgtgacc ttactggcaa tatcctgcct gggaacacat
    11641 ggagtcaagg gtgaaaaaat cacctggccc aaaatctacg cggcgctggt agccggatgc
    11701 gtgctgtttt ttctgaactg gtggctgctt gacctgtccc tgccccacat gacaagcacc
    11761 atactgtacg tcgtaacact taccgcaggt tacctcggac tgctgatggc ggggttgtgg
    11821 atgagccggc tttacaggca taacctgatg ggcgatgtgt tcaatatcga aaacgaatcc
    11881 ttccaacagg aaacccggtt attggagaac gagtattccg tcaacctgcc caccagcttc
    11941 cgctttcagg gaaaacagca tgacggatgg atcaacgtgg taaacccctt ccgcgccacc
    12001 atcgtgctgg gaacgcccgg ttcaggcaag tcgtatgccg tggtaaacaa ctacatacgc
    12061 cagatgattt ccaaaggata cagttgctac atctacgact acaagttcga cgacctctcc
    12121 accatcgctt acaacacgtt gctgaacaac atggacaagt acaaggtcaa gccccggttc
    12181 tatgtcatca atttcgacga tccgcgcagg tcacaccgct gcaatcccat caatccggaa
    12241 ttcatgacgg atatctccga cgcgtatgag gcgagttaca cgataatgct caacctcaat
    12301 cgcacc
//
