LOCUS       c00008_gnlPro..        16322 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BBNPNEOG_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 05:51:30
            Original ID  :: gnl|Prokka|BBNPNEOG_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16322
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16322
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2770:6322](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2771..6322
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16322
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16322
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(198..1397)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MTKKALYIFNPEHDLALASGETNYMAPASARQMASELALLPMWYA
                     EEGSVVLAPSAYNLDYVKKIQELLGLSVDLMTEPELASERNLDIRPWGWDIAIRKRLLD
                     LGVEESELPSIEQLDKLRFCSHRSCAVGLLPQLQLGACFCGESFYLTFPEEWKSFVESH
                     DTCLLKAPLSGSGKGLNWCKGVYTPSISGWCSRIGNQQGGVIGEPLYNKVEDFAMEFRS
                     SGNGRFGFAGYSQFRTGGSGAYEGNLLISDAAIERNLLEYIPVEEIYKLRDRLEQELSL
                     RFGTIYNGYLGVDMMICRFPESPVYRIHPCVEINLRMNMGVVARHIYDHYIYPTSTGAF
                     QISYYPTEGTAWRAHKEMEEAYPLEIEQGRIKSGYLSLVPAHKKSSYRAWVFISKSVFL
                     "
     CDS             1560..2738
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     RELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             2771..6322
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="PFOR_II (E-value: 6.3e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.4e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.4e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.5e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 4.1e-08, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0002, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-24, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(6283..6432)
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="MNSSGKKVVLFMLDRVHTIKNGNLLQDYRFLFIGYYYYSAPQFSL
                     AKRL"
     CDS             complement(6474..7346)
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MHVRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAM
                     SHLAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEF
                     LGEVYGEARVGLVVPQYVTIQSINELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGL
                     DGYTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEI
                     HAIAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVD
                     SWIPKSENK"
     CDS             complement(7364..8188)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-28, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLATLAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(8185..9411)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGD
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(9710..10048)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             10132..11427
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPNKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKRITDLNIPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANISKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQKNQRWWNKPKTNKLIMN"
     CDS             complement(11569..14451)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62; E-value: 2.1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 3.8e-19, bitscore:
                     62.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLLCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLHRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDILEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQR
                     RMLLLVQRNVNILLRLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAAARKKH
                     IHFSFDYMPDTDYRTLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIR
                     FTVANTGSMISAEHIRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQG
                     TIFTVDLPVQTCETVVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLN
                     DALTYEEEELEKSYDSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAADGSEGIRKAMK
                     YVPDLIISDVMMPGMDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYI
                     SKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGD
                     SNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGY
                     EVGFSSPSYFTKCYREQFGESPTDLLKRKG"
ORIGIN
        1 taggttttaa aaaatattga gtaaactaac ttaggtataa caagcgaagt tgtcaactaa
       61 atccagtaca gtacatcaca tggcatgtga ttacttgttt catgcaatga aactttttgt
      121 ttctcggtgt ggaaccaatg gtttcactgc atgaaactat cagtttcaca ccgagaaacc
      181 ataacttcga tataatatca caaaaacacg ctttttgaga taaacaccca cgcccgataa
      241 ctactctttt tatgagccgg caccaatgac aaatagcctg attttattct tccttgttct
      301 atttccaaag gataagcctc ctccatttct ttgtgtgctc tccaggctgt tccttccgta
      361 gggtaatagc ttatttgaaa agctcctgtt gaagtaggat agatataatg gtcataaata
      421 tgacgcgcta ctactcccat attcatcctc aagttgattt ccacgcaagg atgaatccga
      481 taaacaggag attctggaaa gcgacagatc atcatatcca ctcccaaata accattataa
      541 atggttccga aacggaggga taattcttgt tcaaggcggt cgcgcaattt ataaatttct
      601 tcgacaggga tatattccaa aagattccgt tcgatggctg catctgaaat cagcagatta
      661 ccttcgtacg ccccacttcc acccgtacgg aattgagagt atccggcaaa gccaaatcga
      721 ccattacccg aagaacgaaa ttccatagca aaatcttcca ccttattata tagaggttcg
      781 ccaataacac ctccttgctg gttgccaatg cgtgagcacc aaccggaaat ggaaggagta
      841 tatacacctt tgcaccaatt caaccctttt ccgctaccgg ataaaggagc tttcagtaaa
      901 caagtatcat gtgattctac aaatgacttc cattcttcgg gaaacgtcag gtaaaaagac
      961 tctccacaaa aacaggctcc cagttgtagc tgtggtaata atcccacagc gcaggaacga
     1021 tgggaacaga aacgcagttt atccaattgc tcaatagaag gaagctcgct ttcttccact
     1081 cccaaatcca acagtcgttt tcttattgct atatcccagc cccaaggacg aatatccaaa
     1141 ttccgctccg aagcaagttc aggttctgtc atcaaatcaa ccgaaagtcc taataattcc
     1201 tgtatcttct tcacatagtc gagattataa gcggaaggag ccaatacaac acttccctct
     1261 tctgcatacc acatcggcaa caaagccaat tcggatgcca tctgccgggc ggaagccggt
     1321 gccatatagt ttgtttcacc gctggctaac gccaaatcat gttccggatt gaatatataa
     1381 agagcctttt ttgtcatttt aaacgaattc aaaactttat tctgcaaata tatacaggaa
     1441 atagtcagga atggctacaa taaacagaaa gttctaatta aactcacaat tttgccatct
     1501 ctactttgca aatcctaaaa aaagcagtat atttgccacc cgaaaaacaa agaactgaaa
     1561 tggaatcatt ctatcgcaca cacgcctacc tcgttgagca caccaatgcc cccgttcgcc
     1621 gcgatcttat ggacgagatc gactggagcg accgcctgat tggtatcaaa gggacacgtg
     1681 gcgtaggaaa aaccactttc cttctccaat acgccaaaga aaaatttggg aacgaccgct
     1741 cctgcctgtt catcaacatg aacaacttct acttctctgg ccacagcatt gtagactttg
     1801 ctaacgaatt ccagaaacgt ggtggaaaag tattgttgat cgaccaagtg ttcaaacacc
     1861 cggaatggag cagagagttg cgcatgtgtt acgaccgttt tcctaatttg aaaattgtct
     1921 ttaccggctc atctgtaatg cgactgaaag aggaaaatct tgaattgcgt gatattgcaa
     1981 aaagctataa cctgcgcgga ttttctttcc gcgaatacct gaacttacaa acaggcatga
     2041 aattcagggc ctacagtctc gaagaaattc ttagcactca cgaacagatt gccaaaggag
     2101 tactctctaa agttcgtccg ctggattact tccaggatta cctgcatcat gggttctatc
     2161 cattcttcct cgagaagcgt aacttttcgg agaatttgct gaaaacgatg aacatgatgg
     2221 tggaagtaga tatcctgctc atcaaacaaa ttgaactgaa atatctttca aagataaaaa
     2281 aattactata tttgctcgct gtcgacggac cgaaggctcc caatgtgagt caactggcaa
     2341 gcgacataca gacatctcgc gccacggtga tgaactatat caagtatctg gcagatgcgc
     2401 gactcattaa tctggtttat ccgaaaggag aagaatttcc taaaaaacct tccaagataa
     2461 tgatgcacaa ctccaacctg atgtattcca tctatcccgt gaaagtggag gagcaggatg
     2521 tactcgacac attctttgca aattctttat ggaaagacca taaggtacat aaaggagata
     2581 aaaacgtctc ttttatggtg gacgaagtaa tgccgttcaa aatttgccag gaaggagcaa
     2641 agatcaagaa caatccgaat gtgacgtacg cgttgcataa ggctgaaata ggtcggggca
     2701 accagatacc tctctggatg ttcggctttt tatattaaaa gatttattta cttaaatatt
     2761 taatttagtt atgactaaac agaagaaatt catcacttgt gatggtaacc aggctgcagc
     2821 gcatatctcg tatatgttct ctgaagtagc tgctatctac cccatcactc cttcttcgac
     2881 tatggctgag tacgtagacg aatgggctgc cgcaggacgt aagaacatct tcggcgaaac
     2941 agtattggta caggaaatgc aatctgaagg tggtgctgcc ggtgcagttc acggttctct
     3001 tcaggctggt gcgttgacta ctacttacac tgcttctcag gggcttctcc tgatgatccc
     3061 taatatgtac aaaattgccg gtgagttctt gccttgcgta ttccatgtat ctgctcgtac
     3121 attggcttct cacgcattgt gtatcttcgg tgaccaccaa gacgtaatgt cagctcgtca
     3181 gactggcttt gcgatgttgg ctgaaggctc tgtacaggaa gttatggatt tggctggtgt
     3241 tgctcacttg gctaccatca aatctcgcgt tccgttcatg aacttcttcg atggtttccg
     3301 tacatctcac gaaatccaga agattgaaat gttggaaaat gatgatcttg ctccgctgat
     3361 cgatcaggaa gctttggctg aattccgtgc ccgcgcactg aatccgatga atccggttgc
     3421 tcgtggtatg gctgaaaacc ccgaccactt cttccaacat cgtgaatcat gtaacaacta
     3481 ctatgaagca gttcctgcta tcgtagaaga atacatgaat gaaatttcta agattacagg
     3541 tcgtaaatac ggtttgttcg attactatgg tgcagaagat gcagaacgcg taattatcgc
     3601 tatgggttct gtaacagaag ctgcccgcga agctatcgac cacttggtag caaatggcga
     3661 aaaagtgggt atggttgccg tacacctgta tcgtccgttc tctgctaaac acttcctggc
     3721 tgctgtacct aagactgcca agactatcgc agttcttgac cgtactaaag aaccgggcgc
     3781 taacggcgaa cctctttacc ttgacgttaa agactgcttc tacggcgcag aaaatgctcc
     3841 ggttatcgtt ggcggtcgct acggtttggg ttcaaaagat actactcctg ctcaaattct
     3901 ttcagtattc gaaaacttgg ccatgccaat gccgaagaat cacttcacta tcggtatcgt
     3961 agacgacgtt actttcactt ctcttcctca aaaagaagaa atcgctttag gcggtgaagg
     4021 aatgttcgaa gctaaattct acggtttggg tgctgacggt acagtaggtg ctaacaagaa
     4081 ctctgtaaag attatcggtg acaacactga caaacactgc caggcttact tctcttatga
     4141 ctctaagaag tcaggtggtt tcacttgttc tcacttgcgt ttcggtgata ctccgatccg
     4201 ttccacttat ttggtaaata ctccgaactt cgttgcttgt cacgttcagg cttacctgca
     4261 catgtacgat gtaactcgtg gtttgcgtaa gaacggttct ttcttgctga acactatctg
     4321 ggaaggtgaa gaactggcta agaacctgcc taacaaggtt aagaaatatt ttgcacagaa
     4381 caacatttcc gtatactata tcaacgcaac acagattgca ttggaaattg gtttgggtaa
     4441 tcgtaccaac actatccttc aatctgcatt cttccgtatc acaggtgtta ttcctgtaga
     4501 ccaggctgtt gaacagatga agaaattcat cgttaagtct tacggtaaga agggtgaaga
     4561 cgttgttaac aagaactatg ctgccgttga ccgtggtggt gaatacaaga ctttagctgt
     4621 tgatcctgct tgggctaacc tgccggatga tgcaaaagct gaaaacaacg atcctgcatt
     4681 catcaacgaa gtagttcgtc cgatcaatgc acaagatggt gacttgctgc ctgtatctgc
     4741 attcaagggt atcgaagacg gtacttggta tcaaggtact tctaaatacg aaaaacgtgg
     4801 tgtagccgca ttcgttcctg aatggaatcc agaaaactgt atccagtgta acaagtgtgc
     4861 atacgtttgt cctcacgctt ctatccgtcc gttcgtactc gatgctgaag agcagaaggg
     4921 tgctaagttc gaacaattga aagcagtagg taaagtattc gacggtatga cattccgtat
     4981 ccaggttgac gttctcgact gtctgggttg cggtaactgt gctgacatct gtccgggtaa
     5041 tccgaagaag ggtggcaaag cattgacaat gaaacacctc gaaagccaat tggctgaagc
     5101 tgacaactgg acttactgtg ctgaaaacgt gaagactaaa caacatcttg ttgatatcaa
     5161 gtctaacgtg aagaactcac agttcgctac tccgttgttt gagttctctg gtgcttgctc
     5221 tggttgtggt gaaactccgt atgtgaaatt gatttctcaa ttgttcggtg accgtgaaat
     5281 ggttgctaac gctaccggat gttcttctat ctactctggt tcagttcctt ctactccgta
     5341 tactacgaac gaaaacggtc acggtcctgc ttgggctaac tcactgttcg aagacttctg
     5401 tgaattcggt ttgggtatgg aattggctaa tgaaaagatg cgtgctcgta tcgtgaagtt
     5461 attcaacgaa atccttgctg ccgacaacgc ttcacctgaa gcaaaagaag tgctgaaagc
     5521 atggattgaa aacatgtacg atgctgacaa gactaaagaa ttggctcctc aagtgaaagc
     5581 agtgattgaa gaaggtcttt ctcacggatg tcctatttgc aaagaactga aaggactgac
     5641 tcaatatctt gtaaaacgca gccaatggat cattggtggt gacggtgctt cttacgatat
     5701 cggttatggt ggtcttgacc atgtaatcgc ttccggtaag gacgttaaca tcctcgttct
     5761 ggatactgaa gtttactcta acacaggtgg tcagtcttct aaggctactc cggtaggtgc
     5821 tatcgctaag ttcgctgctg ctggtaagcg cgtacgtaag aaagacctcg gtctgatggc
     5881 tactacttac ggttatgtat atgttgcaca gatcgctatg ggtgctgacc aagctcaaac
     5941 tctgaaagct atccgtgaag ctgaagcata tccgggacca tctttgatta tcgcttacgc
     6001 tccatgtatc aaccacggtc tgaaagcagg tatgggtaag agccaggaag aagaagaaaa
     6061 ggctgttaag tgcggttact ggcacttgtg gcgttacaac ccggctctgg aagaagaagg
     6121 caagaatcca ttccaattgg atagcaaaga accgaactgg gaagatttcc aaggtttctt
     6181 gaaaggtgaa gttcgttacg cttctgtaat gaaacaatat cctgctgaag ctgaagaact
     6241 attcaaagct gccgaagaaa acgctaaatg gcgttacaac agctacaaac gtttggctag
     6301 agaaaactgg ggtgctgaat aatagtaata ccctataaat aaaaaacggt aatcttgtag
     6361 aagattaccg ttttttattg tatgaactct gtccaacata aacagtacta cctttttccc
     6421 actagagttc atgtctattt tatatttaaa attaagaata acaatgctcc aatctattta
     6481 ttctctgact tcggaatcca actatccacc aacagccgat gctcatccct ccatttacgg
     6541 gctatttctt cttcatccat cctggcatcc ttcatagctg tcataaaaga gctaagttct
     6601 tctgtcgtta gtttgatgtt gccaaagaac tcggcagcaa acggatcttt ctcactgaat
     6661 cctttccatg caatagcatg tatttcttcc aagtctccat atactttctt cggatcatcc
     6721 aagaatttca agtcaaactg gtcgaacatc caatgcggtg tccaccccgt aatgacaatc
     6781 cattctcctt tgtccatcgc ttttttcaaa gaagccagca tggtggaact acttgaagtc
     6841 atgagggtat acccatcaag tccgtaagca gcaatggcct tatcggtcgt cttcattatc
     6901 cctgctcccg catcaattcc tactatttca gaagaaaaac ggtctttatt agcttccagc
     6961 tcattaatag actggatcgt aacatattga ggaacaacca gtccgacgcg agcttctccg
     7021 tatacctccc ccaaaaattc gatgctgtct ccatactgat ccatataatc tttcatcgtt
     7081 attggtaacc aggcatccag aaacacatct gatttctttc ctgacataga tacaaaaata
     7141 ggggcaagat cagcattttg caattcaacc tcatatccat gctcttccaa taccacctta
     7201 gccaaatgac tcatggcaat accttccagc caattggcat aggctatttt tactttcttt
     7261 ttctctaagt ctgaattagt acaggaagct agcaaaagca tagccgaaag cactattcct
     7321 actattttat atattctcac atgcattttt attcctttcc gttttagttc ttattttttc
     7381 gtcctgccat tccttgtgtg atacggtcta agatgatagc taaaataaca acagctatac
     7441 caccttcaaa cccaagtccg attttcattt gggtaatacc tttcaataca atttctccca
     7501 gaccaccggc agcaatcatg gcagcaatga caaccataga aagcgacatc ataattgtct
     7561 ggttgacacc tgtcagaatg gtgggcaacg ccaaaggaag ctgcacttta tacaataact
     7621 gccaacgggt agccccgaac gaacgggaag cttccactac atttttagga acttgccgaa
     7681 ttcccaatcc ggtaaggcgg actacaggag gcatagcaaa gataatggta gcaaacactc
     7741 ccggcactgc tcccaatccg aaaaacaaaa cagcaggaat cagataaaca aaagcaggca
     7801 tcgtctgcat caagtcgaga acaggacgaa gtattttctc tgcacgcgga ctgtttgccg
     7861 tccacactcc taaaggtaca ccaacaatca gagccagaca ggtagatgaa aaaacgagag
     7921 ccagggtttg catagtagcc tcccagaatc ccattccata gatcagtaat aatcccaatg
     7981 cggtgaaaat tgccgtaccg cgtcctgctt tcatccatgc gagtgtagca agtaccaaaa
     8041 tggttatata aaaaggtatt ccgaaaagta tgtgttggaa tcctataata aaactaccga
     8101 tgcccgcatt cacggcatca aagaaagtgg aaaaatgtac catcatccaa ttgatggcca
     8161 tctctatata ttgtcctata tttatcataa atctattgcg ttttgaatta tttcgtttat
     8221 ttcttctttg tctttcccgg tcacttcgat gattaaggat gaaagcggga ttgttcctaa
     8281 aaactcgcgc gtctcatcaa tcacccatac cggcgaattg ctctttgtca ttagaggaag
     8341 tatatcctcc aacaccgtat cctccaacac agaatgtact tctgtacgca caatcgtttc
     8401 aatggatttt tcctgtttgc tacgtaactt aagcaagtcg ttcagacgta cttctccgac
     8461 cagtttatca tcggcgtcta tgacaggtaa tacggtgata ttcttcgcac gcatcttacg
     8521 aatcaatact tcgggacctt ctttcttcag acgggccacc aacggtttgt caatcattaa
     8581 agaagaggcg gtaataattt tgctcctatc cacgttttca acaaaacggg ctacataatc
     8641 gttagccggt tcagtcagga tttcctccga agtacctacc tgcaccactt ctccgtcttt
     8701 catgatggca atacggtcac ctagcttaat tgcttcactc aagtcgtggg taataaaaac
     8761 aatcgtcttt ttcatctttg attgcaaggc cagtagttca tcctgcatct gtacgcgaat
     8821 cagaggatcg agagcagaga aagcctcatc cattaaaagc acttcaggat tattagccag
     8881 agcacgagcc agtccgacac gctgttgcat tccaccggaa agatcgccta ccatctgatt
     8941 ttcatatcct ttcaatccga caagcttcat gctttccatc gctttcttct cacgttcctc
     9001 tttcttcact ccctgaagtt cgaggccgaa cgcgatattg ctcaatacgg aacggtgagg
     9061 taacagaccg aaattctgga aaaccatcgc cagctctttc cggcgaacct gcaataattc
     9121 tttttcggaa attttagata tatctactcc gtttacaagc acttgtccgg cagtaggacg
     9181 tatcagacga ttgatacaac gcagtaatgt cgattttcca cttcccgaga gtcccattat
     9241 cacgaaaaac tctccttcat taattgaaag attggcatct ttcactccta ccgtacaacc
     9301 ggtatctttc agaatttcct ctttactctt atcttttttc aacatcttga gggctttctg
     9361 cttctcgtta ccaaagataa ggtacaaatc ctttatttct attttactca tataatatat
     9421 tggtttagat tataatattt gttttgtttt caactgccgc attccttatt ctcacttacg
     9481 ataaacaagt tgaatgttcg catggttcag tcatgccaca tgataacatg acggtccgac
     9541 gttttttaaa tggttaaaaa aaacagacag agtagtttaa aaggaataga atttgataag
     9601 attatcctct taatgaacag tagaaaatag tattttcata aataaataac agtctgttct
     9661 tgcatattgt tggcacaaag gtaaggaaaa tagattaaat atgcaaattt cattcaggta
     9721 cggagtaatt ccaaagatgc tttttcaagt ctacgcatcc attttgtttg aaagagatcc
     9781 cttcttccaa caagagttgt ttctgctctg tccaacccgg aacaagccgt cccgacgcat
     9841 tgacaacccg atgacaaggc gcagataaat catccggaat ctgtttcaaa gcacgcccca
     9901 ccatacggga acattgagac attcccaata atgcggcaat tcccccatag gtagaaactt
     9961 tacctaccgg aatttctcgg acaacctgat acacctcttg acaaaaggat gcggaaaggc
    10021 tcgccttatc tactttataa tctttcatca ctcaaacatt actttatttc agttccaaaa
    10081 ctagataaaa agaaaagaat ttgcaaataa taaaagcatt tcaaataaaa tatgcaactt
    10141 tatttgcttt atttacaaat aatcccgacc tttgtcccca ataaaagcaa ccctattatt
    10201 aacaaaacaa gcactgctgt tatgaaaaag aaaactatcc tgttcgcttc ttgtttattg
    10261 ggagcactgg ctttcagctc ctgtgagaag aacctttatg atgaaagtaa acaacccgag
    10321 aaagaaaaga gaataacaga cttgaatatt cctgctgact ttgattggaa aggttctcaa
    10381 aatgccaaag tgaaaattgc cagtcaatca actgctacta tttctgtatt tctagaagaa
    10441 aattgcaatg aagaggcttt gatgcttcga atggatgtcg atgccaacat atcaaaattg
    10501 gaactcccaa ttgaaattcc tgcatatata aaaaatgtgt atgtaaaata tggtaatggc
    10561 tctgaaatac aaactgttcc tgttgaaagt aatggtacta tttctatagt agtacctgct
    10621 aacgctacgg cattatccag agttaccaca agagctaata aagaagttga aacgaacaac
    10681 atcttcaatt atccgggata tggcaacgga actattatgt tcgaagatat gtatccagct
    10741 ttaggcgatt atgattttaa tgattttgtt gcatggtata atttccaaat tgacggtttt
    10801 tattggagtc acaatcaatg ttatgcagaa tacttaatga taggattcca aatcagagct
    10861 ataggaggta tatatgacta caatccttat atccgcttgg cagaagtaca atataatgaa
    10921 cttgatttag aagaaactca aatgtatctt gagcgtaaca atcctgaaga ggctgaaaat
    10981 atcaaaatcc taaaaggccc aaaaggggaa ttgattattt cactaaagaa accggccatt
    11041 cctaacggat acaagtatta taatacggag gtaaatgaaa aaacaaagcc taaaaaaatg
    11101 atggccattt acttggtgtt caactcacct gttaacgtta aaagcctaca agacagtaaa
    11161 atggactttt atattgcaaa aactaataaa ggacaagaaa tccacttaaa aggttatagc
    11221 ccggtttatt ataacagcaa cgaaagttat gtaaatgaag acaactttat atggggatta
    11281 aaagtacctg catctttaca tcatgccaga gaagaagtaa acttcttgga agcatatcca
    11341 gactttgaac aatgggtaac atcgggaggt caaaagaacc aaagatggtg gaataagcca
    11401 aaaacgaata agttgattat gaattaataa atatacagta aatcatatac tgaattaaat
    11461 aagaggtaag gtatgtcaat agatttcctt acctcttatt tttatcatat gaattccata
    11521 gaagtataaa cagataaatg ctcaccatca aattttgcag attctatcct atcctttcct
    11581 cttcaacaaa tctgtcggac tctctccaaa ctgttctcta taacatttag taaaataaga
    11641 aggagaacta aaaccaactt cataacctat ctctgccact gtcatatccg acgaggcaag
    11701 cagagaagca gctttcttca aacgagctat acgaagcagt tcattcggag aataattagt
    11761 cagagattta atcttgcggt aaagttgcac acgacttaat cccatatcct tacccaaatc
    11821 ttctacattc aaatttgaat ctcccatctt tgcctcaatc agagctttga atttttccac
    11881 aaagtcttta tccatatcac agacatcctc tttcgccaac gtttgtccgt caccaaaaaa
    11941 ctgtttcagg cggcggtgtg aatctatcag attacgaacg cgtgccaata gtaattgcga
    12001 actgaaaggc ttggagatat aagaatctgc accaccatca tacccttgaa ttcgttgttc
    12061 atccaaagaa caagctgtca ataggataac aggaatatga caggtttgta attcgctttt
    12121 caagcgacga caacattcaa ttccatccat tccgggcatc attacatcgg agataatcaa
    12181 gtccgggaca tatttcatag ctttacgaat accttccgag ccgtctgcag cttctataac
    12241 agtataatca gtgtgaagca atccatgcac atataagcga atatcagcgt tatcatcaat
    12301 aatcagaacg caaggtttgg aagagtcgta acttttttcc aattcctctt cttcgtaagt
    12361 taaagcatca ttcaagctcg aagaaccgga ataaccagaa gttgcaggag ttacgggagc
    12421 cccagcaacg gcagaggttg cagcatcggt ggaggttaca gaagtagcag ggacagagaa
    12481 tgccggagag ttttcagaaa caacagtctc gcaagtctgt acaggcaaat caacggtaaa
    12541 gatagttcct tgcttttcat cactttccac tgtgatggta cctttatgca attccacaaa
    12601 agcctttacc aatgccagtc caatacccga accggcatgg tgcatatcta tcttatagaa
    12661 acggtcgaaa atattccgga tatgctccgc agaaatcatt gagccggtat tggcaacagt
    12721 aaagcgaatc caacaatgat cgtctttagt cagggaagat aagcgtacag ttacttttcc
    12781 attctccgga gtaaatttga aagcgttgga aaggaggttg aaatagatgc gttccaactt
    12841 ttctacatct gccaatgtgc ggtaatccgt atccggcata taatcgaatg agaaatgaat
    12901 atgtttcttc cgggctgctg ccatgaaaga ctcgttccat ccctcaaaag aagaaagaat
    12961 gtctaacgaa ataggagtat attccatttt tccattctcg tatttacgaa aatccagaat
    13021 ctgattgaca agacgcaaga ggatattcac gtttcgctga actaacaata acattcggcg
    13081 ctgatcttca ctcaaagacg aatcagccag taaatgctct accgggtcgg caactaatgt
    13141 cagtggagta cgaaaatcgt gagatatatt tgtgaagaaa accagcttgg catgagtcgc
    13201 ttcttccagt tgatgagaaa gctggataag ctgatcccgc tgttcttcga gtttgtcacg
    13261 ctgttcttca agaatatccc gttgctcttc gagtttatcg cgctgttgct ctacttgttt
    13321 cttctgttcg gacaactctt tattcaggcg attcttggaa cggagggatt tatagactac
    13381 caacaacaat cccgctacta ataaaagaat aaccaagccg ccatacatca cgacctgctg
    13441 cgtagctaca cgcgacagat acccaccgat acgtccgttc aatgtttcaa tcttctgatc
    13501 cagttccgag atatgggtag tctgaagttg cataacgtgc gcgttcgtgc ggtctacaac
    13561 ggcagtattc atgaccgttt cgcgaggata agacttcttc tcaagaatat tcatggccag
    13621 ttgcatcact ttgtccccat tagtcggata aataaaagtt gcatcgagca cattgtcaag
    13681 caccaattca agcccgtttc ctttgccggg cagggcatca atgccaacaa aaatcatttc
    13741 cttttcacgt ccggctttct tcgcagcctg ataggctccc ggagcgatac ggtcgttatg
    13801 tgcatacacc gcatcaatct tcggatgacg gtgaagcata ctatccattt ccacttctgc
    13861 cggttcacgt tcccaggcag catccgcttt atcaatcagt ttgatatccg gataattgct
    13921 gatagcggcc ataaatccct gatggcgctc catagcaggg gtggaaccac ccagtccggt
    13981 aagctccact acattccctt tccctttcag acttgatgcg atataatttc ctaccgcacg
    14041 acctatttca taattatcgg caccaatata ggcagtatat ttatcagaaa gtatcttccg
    14101 gtctacaaga atgacaggta ttcctttctg ataggcctcc tccacaattg gagtcatggg
    14161 agccgcttca ttggcggaaa ttatcagtaa atcaactcct ttatctataa aataatgaac
    14221 atcttccgcc tgcttacggt tatcatccgc cgccgaacgg atttcaaccg acactccatc
    14281 ataaaacatc gcttcgcgaa gaatctcatc attcatcttg tgcctccaag agtcatcgct
    14341 acattgggcc accccaatac ggaaacgagg cgcatcctgc cgacaggccg ccaagcccaa
    14401 aagacaaagc aagactgtta tccacttcgt atatttcatc gcttcaatca ttccctttct
    14461 ttcgtatatc ttttgtattt ctttctgtaa tccaaatttc tctccccgca ttatttgcat
    14521 tcaccaccgg gaaatacatc agttccactt tcacagggtt cagcgtatat tttccagtaa
    14581 agcgtggaag caaaggaacc gtaaactgat aagtacctac cggtaatttt tcgctaaaga
    14641 taacagtttt ctctttaaaa tactcacgat atacttcaga acgggagaaa ttaacaggtt
    14701 ttgaggcata actacaacct gccggaacag gaacttcgag catcacatat tgcgcaccct
    14761 cctgtttcac ctgcaaggta actgtcaatg taacaggtac acccgccacc aaagagtctt
    14821 tttccaaagt cacctccacc ttgaaagcat cactctgacg agcattcatc acacgcttca
    14881 ttgaatagac actatacaat aaaggctctt ttcccgtttt tgaaataagc agactgtcgc
    14941 ctgctgtcag ccgggcatga taaggaaatt ccgtaattcg ttgatgatcc ttaccgctca
    15001 cagacaccga cgttcctgac atccctccgg aacctgccag caaatcggtc agaacagttg
    15061 ccacagccga agaagcctga tacgtattcc atccgcgctc cttagtccgc aaaatataca
    15121 attgcatatt ttctttcaac ttacacaggg aagggtcatt tttaataatc cggtaggcta
    15181 tcaatgtatt tatcatctga tttccctccc aataataagt acgccgtccg tcgtcacagt
    15241 aaacaccttc cagcatatcc tttttcagat aaggacgtac gctatcaccc acattcaccg
    15301 aatccacctg ttgcttgatt tcccagagaa gcagcttctc tttcaagtat gaaagaggac
    15361 gataatactt gtttctattt gccaacgagt cttctttctg ttccaattgc cggacgaaag
    15421 gttccaataa tctgactgcc gaagaataat ccgcctctac tttccactca tgcagagcat
    15481 gaagtatttc tatatcttcc agtttcattc ctcgataagg acgcgtatga gcatactcca
    15541 ctttcaaacc attcagattc aactccacag gataacctgc atcttgcgcc atcttcaaag
    15601 cccgcagaat atgcgcagac atccagaaag aagtattttc agagttcccc caccacgacc
    15661 ataactgatg tttgttctga tgattcgtca gtcgatggat gataggtcga attgctttat
    15721 ctactttcac cttttcaccc ttactctgca tatactgttg gtaagccaac aaaccggtta
    15781 acttggatgc cagctgctca ttgcacaaat atttgtatcc tgtcaagtaa ttcactgatt
    15841 ctttatagat gtccaactga ttgtcagtga tactcaccat cacttcttca tcctcgccgg
    15901 attgcacttt gaccgtcttt gcatcggaca gaatacccaa tgtgccctcc gccaattcag
    15961 ttccctgtgg cagtatcgga atcgtatatt cctctccatc ctgatagcca tcgtcgcgag
    16021 tgaaaagata gctgatggtc acgctatcgg catgaactgc ctgcatcggc actgtttcat
    16081 gaaatccctc catgaaactc acttcctgcc gtttcaacgt atccgttccg acgcagaact
    16141 gtgtctttcc ggctatgtgc tgcccatcca gataattgcg gatagtcccg accaccgtac
    16201 tctgatcccc ctccaccaag aagcggggag ttttcaactc cgccatcaac ggtttgtaag
    16261 agcggacgaa acgtcggaaa gtacccgtct gcaaacgacg gttcatgcca taaacgacag
    16321 tt
//
