LOCUS       gnlProkkaCFLJKNLG_60   13748 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CFLJKNLG_60.
ACCESSION   gnlProkkaCFLJKNLG_60
VERSION     gnlProkkaCFLJKNLG_60
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 09:29:24
            Original ID  :: gnl|Prokka|CFLJKNLG_60
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13748
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13748
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3397:3748]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3398..3748
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13748
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13748
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             232..1743
                     /locus_tag="ctg16_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPVLTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEEIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             1816..2883
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELTSVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPTVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             2920..3204
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3398..3748)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_4"
                     /sec_met_domain="PqqD_RRE (E-value: 1.5e-10, bitscore:
                     33.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.2e-17, bitscore: 55.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPAGMSKELHVRLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(3846..5234)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 95.3; E-value: 4.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg16_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGYTDEGGAFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSLMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMTIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5482..5877)
                     /locus_tag="ctg16_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             complement(5884..6657)
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGFELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETIKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6663..7190)
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPSQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSTQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7177..8418)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 385.8; E-value:
                     4.8e-117)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="MTRAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQVGTVVTTPVVTTHQPSVPA
                     IIHTMQPAVCKDDDDIQDTEEYVEEPPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8428..9522)
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9527..10567)
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQNQIPLGEASKE
                     AEQTNK"
     CDS             complement(10586..11620)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_12"
                     /sec_met_domain="PF04055 (E-value: 7.9e-18, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 agaaatcttt ttcagggaga aataaaagta agttcataat ggtgcagcat tgaattattt
       61 tttggcggag ttattctaac acttaatagt tcaaaagcag atatttcttt gaccaaaaga
      121 tagaactaat gatgaattaa aagttgcaat tatggttttc ttcccacaac aaacgggaaa
      181 agtcagaaga atcatgtaca tttgtaatcc gaaaactaaa agaacatcgc aatgaaaata
      241 tttccaagca gcagtatcaa gaaattggac gcttatacca ttgagaacga acctattgca
      301 tcaatcgatc tgatggaacg tgcagcaacc gtattaacaa aagccatcac agacagatgg
      361 aatacggaaa caccggtcac tatctttgcc ggaccgggga ataatggcgg agacgctctc
      421 gccgtagccc gcatgatggc tgaaaaagga tataaaatcg aggtatttct cttcaacacg
      481 aaaggagaac tttcacccga ctgccagacc aataaagaac tggtagaaat gatggaagaa
      541 gtaaaattcc acgaaatcag tacccaattc gtacctcccg tcctgacgcc cgatcatctg
      601 gtaatcgacg gattattcgg ttcaggtctg aacaaaccgt tgagcggtgg attcgctgcc
      661 gtagtgaaat acatcaattc ctcccctgcc atggtagtag ccatcgacat tccttccgga
      721 ctgatgggag aagaaaatac attcaacgta aaagctaata ttatccgcgc cgacgtaact
      781 ttcagtctgc aactgccgaa gctcgccttt cttttcgcag agaacactga atttgtcgga
      841 gaatgggaag tgctggatat ccaattaagc gaagacggta ttgaagagat ggagactaac
      901 tacgaaatgt tggaaataga agaaatccgt tcactcatca agccacgcaa acagtttgcc
      961 cacaagggga acttcggcca tgcactattg attgccggtt caaaaggaat ggcaggagcc
     1021 tctgttctcg ctgcccgcgc ctgcctccgt tcgggagtag ggttgctgac tgttcatgca
     1081 ccaatgtgca acaacgacat cttgcagacc tccatacccg aagcaatcgt agaaaccgac
     1141 atcaacgaaa cctgttttgc cgtacctacc gatacggacg actaccaagc agtcggcatc
     1201 ggcccgggac tgggacgaaa cgaggaaacg gaagctgcct tgttggagca actggaacac
     1261 tgccagactc ctgttgtagt ggatgccgac gctcttaata tcctcgccaa ccaccgccat
     1321 acccttaccc acctgccgaa gggttccatc ctcaccccgc atccgaaaga actggaacgt
     1381 ctgaccggca aatgccagga ctcttacgaa cgtctgatga aggcttgcga actggcccgt
     1441 gccgcccatg tccacattat tttaaaagga gcctactccg ccattatcac cccagaaggt
     1501 aaatgtttct tcaacccaac cggaaatccg ggaatggcaa ccggaggtag cggtgacgta
     1561 ctgaccggag taatcctggc gctgcttgcc caaggttatc ccaccgaaga agccgctaaa
     1621 atcggcactt acattcacgg attggcgggc gatgtcgctc aaaagaagca aggaatgatc
     1681 ggaatgatcg caagcgatat tatcacctgt ctgccgacag catggcgact tgtaagcgaa
     1741 taaaagttaa gaacttacag ttttttcaat aacttcatta actttgtttt caaaaccagt
     1801 taaaaagaac cgaatatgaa aaagttgatt atagcagcag gactacttat gacaacgtcc
     1861 gcctatgcac aaaccgaagt actgacaggg gttacccgag gaaaagacta tggagtggtt
     1921 tacagtcttc ccaaaaccca aatagaactt gaaataaaag ccaacaaagt caactatact
     1981 ccgggagaat tcagcaaata tgctgatcgt tacctgcgac tgaccaacgt ctccgccgac
     2041 cctgaagagt actgggaact gactagcgta aaagtgaaat ccgtaggtgt gcccaacagc
     2101 gaaacgacgt atttcgtaaa attgaaggat aagacagtag caccgctcat ggaactgaca
     2161 gaggatggca ttgtgaaaac gatcaatgtt ccttacagca acagcagtgt aggcaaaaaa
     2221 gccgctcccg ctcccacagt cctccaaaag aaagcaaatc ctcgtgaatt cctgaccgaa
     2281 gagattctga tggctagctc taccgccaag atggccgaac tggtggctaa agaaatctat
     2341 aacatccgcg aaagcaaaaa tgccttattg cgcggacagg ctgacaatat gccttcagac
     2401 ggagcacagc ttaagattat gctcgacaat ctgaatgcac aggaagaagc catgacgcaa
     2461 atgttctccg gcacctgcaa caaggaagag agaacattca ctgtccgcct tacccctgac
     2521 aaggaattta acaatgaagt tgctttccgc ttctcgaaga agttaggtgt agttgccaac
     2581 aatgatttgg caggaactcc gttttatatc agtctgaaag acctgaaatc ggtcaagata
     2641 ccacaggaag atggtaagaa gaagaaagat ttggatggaa tcgcctacaa cgtacccgga
     2701 caagctatgg ttacattgac cgacggcaaa aagaaacttt acgaaggtga acttcctatt
     2761 actcaatttg gtgtgataga atatctggct ccggttttgt tcaacaagaa ttctaccatc
     2821 aaagtttatt ttgatccgaa tacgggagga ttgctcaaag tggacagaga agaagggaaa
     2881 tagaaaaacg agaaagtgaa cttctaaaaa acaaagaata tggttggtga aggacatgca
     2941 ttcgacatga tacgccgaat aaaagaggga cgggaagctt cccgcctacg tcgtgaacgt
     3001 gctaacgaca agttgaagca tttaaaccgt gcaaacgaac cttatccact acccaatacc
     3061 actcccgaag aaatggaacg tatcatccac gactcggaga aaaagaaaga gaaagacagc
     3121 aattattttg tttggggaac gcttattatc atgggagtcc tgatagcaat tgccgtcata
     3181 ctttgggctg tatttatcaa ataaataata ataaattcac cacagaggac acggaggaca
     3241 cggaggacac agaggtttaa tcttttttat tcactataga gtaacacaga gtctcacgta
     3301 ttgagaatcg tatttatcgc tctgttttac ttgcggaaag agagagagaa gaactctgtg
     3361 tcctccgtgt cctctgtggt gaaatataaa ttcctattta tgcgactggt atcaccagtt
     3421 ttataaatcc atctttctgc atttgagaaa gataagccga tacacgcgac tcgtagccct
     3481 cttcattttg aaaatggtct gcgagttttt ctataatctc acgaacattg cgttttccat
     3541 ctatcagttc ccatacagcc gtaccgtgtt cttccaatcg cacatgaagt tctttcgaca
     3601 ttcctgccgg tacaaggaag cgttgcatcc acggatattt aaaacgggga aaggagagca
     3661 caatcgtctc cccttccctt tctgctgtaa tatgttcact gcgacaggga atgacctcta
     3721 acaggttgat tttctctttg gcagccatac ttcttatttt ttatttcaga gtattcatac
     3781 tgataccctt ttgtttacac cttgatacaa aattcctttg ttactttagg tattgaattt
     3841 cccagttact tttggatatt cgcctcttcc agaccgtatc ccttcttctt gttctctgcc
     3901 ttcaacatca aagccacaat cagagcaagt acaccaaaga gagcaaaaat agtcatcggc
     3961 aatgtgtaat cataagtctg tgcaccgtct accaccggac ctttgcaata agtattcaat
     4021 acccatccga ttaacaaagg aacacccatc agtccccagt tctgtaccca gaaaatcaaa
     4081 gcgtaagcag tacccagctg tttttccgga ataatcttcg gaacagaagg ccacatagcc
     4141 gaaggcacca atgagaaagc aaatcccaat ataatcatta taatagtagc aaaccaccat
     4201 atattcagta taggcagggc aaacatggta tgtacaaaaa ttagcatcaa tgatccgatc
     4261 accatcaatg tggctccttt accgatacgg tcatataacg aaccgaacaa cggagtcagg
     4321 ataattgcac caatcggcaa caatccggga atcgttcccg ccagtttcgg atctacatta
     4381 tatttctgca ccatcaagtc ggcagcatat ttgataaaag ggaagacggc cgagtagaac
     4441 aatacgcaca gcaatgcgat caaccagaat cccttattgg taatgatata cacaatatct
     4501 ttcatacgga acggttcttc cggttccaaa ccttctgcat ccaaagaagc atccaatttc
     4561 ttatcgtaga aagtataaag gaagaaagca atagtaccta cacacagcat aatcagacaa
     4621 aacagaatag gagcaggaat attggtatgg aatgcaccac cctcgtccgt atatccgaag
     4681 aagtctgcca aaggaactgt caacaccatc gccagagttg tcccaatacg tgccgtagcc
     4741 atttcaagtc ccatagccaa tgccatttcc ttgcccttga accatttcac tataatcttg
     4801 gaaacagtga taccagcaat ctccacacct acaccaaaga tagcatatcc caatgcagcc
     4861 aacgtcacct gtgttttgaa tccgaagagc atggcacctt ccggaaaagt agtagaaatc
     4921 gcatagtatt tcaatccaca accaaacacc atcaataagc aagctcccat tccggtgaaa
     4981 cgaactccca ttttgtccaa aatgatacca ccgaagatca gcatcaacaa gaatacgtta
     5041 aaccaaccgt aagcgcttgt gaagaatcca taatcaagac tatcccataa tagttctttc
     5101 tcaagcatgg gttttagagg agacattacg tcggtgagga aatagccgca tagcatagta
     5161 aatgcgacca atgctagaac actccatcgg agtacggcgg agtcattcaa tttctgtttc
     5221 aaatgttctg tcattgttat atttaaaaaa gtagttaata atcttataca gccaacaaag
     5281 gtagttaaat ctcgtttgtt tctatcacaa agagattgtt tttacaagaa aaagttaagt
     5341 gcggattaca ctgaccacgc ggaacattga aaatccgtgt aatctgcgta atccgcactt
     5401 aaatatcaaa gaaatgcagc atccgtctgc accttcccat taatggtttt accccaaagt
     5461 cttacctgac gacggagtga attactctgc tgcaggagca ggagtttcag tagccggtgc
     5521 cggagtttct gtagcaggtg cattggtagc aggagcttca gtttgcggcg cagccgtacc
     5581 tgcgggtaag ttatacgggt tagtctgttg ttctttctgt gcctgttcca acactgcgtc
     5641 tttagcaaca gcagaacgag gaactacata agcagtagca atgctcatta caaccataaa
     5701 gatggccagg ccccatgttg ctttttccag aaagtctgta gtcttgcgca cgcccatgat
     5761 ggcgttagat gaagagaaac cagaagcaag tccgcctcct tttgagttct gaatcagcac
     5821 gatgaaacac atcaacaagg ctgcaataac cattaagata acgaataata agtacatttt
     5881 tagttatttt gaattagcgt taataatcaa tttctccaaa aatctgattt ggtctgcaaa
     5941 gtaagcattt ttttttggat atttcaagct taatttttta attatttcaa gagcttttga
     6001 atatcgttgc tgtttaacat agatttttgc caaagtttcc gtaaaacagc tgtcatcttc
     6061 ctcttcttcc tttatcgttt cttcttcggt aagttcgtcc gaagaggttg gcgaagatgg
     6121 catttcttct cttaaaggtt tcatgcagag gggagagtcg ctctcgctct tttctataaa
     6181 gtcgtcaatc agttcgaagc ctttgagttt gggcgtttct tcagccggtt gttccgtggc
     6241 cggagtctcc tccaaaagat aagaagtgta atccatcgaa tagtcgaaac tggtccgggc
     6301 agtcacctct tcgggtactg tggacaagaa agcgtcgatc aatgctaatg tgcggtctac
     6361 ggacggttcg tctttcagca cctccgtgag aggtactccc tttttccgtg cctgcacatc
     6421 atagcggtca ccttcaatca accggaacaa ctgccgtctg tctgcaatgt aaagaactgc
     6481 tttccgcagt tctccaccga aactaatatc atggagaata tacagattct tcagatacaa
     6541 cagacgaagt gactgaaaat acggatacct cgcaagaaga ttgcgcagtt cgtacaaagt
     6601 atccctattc agcgtctcgg gatgctgaat ccattgttga aagttaacag aagtcattta
     6661 tattaccagt ttgctacagt tgcattaaaa atttggtcgg tgatctcttt agacatttca
     6721 gcaatcaatc cgtcctgtac ggcagtcaac aactgggtag agtcgtaggt acggaacgca
     6781 gaaaactgtt gttcaaagtc ttcggcatga ttggtgttgt tgacaaaacg cacattgacg
     6841 gtgatagtca acttcgtctc cgaagaataa ccgtcggcag atactgcctg gttgtactga
     6901 ttgtaccctg tgatttctcc gtcaatctgc aagtcggcat tttgactcgg cttgagcagt
     6961 tgcagacggg tctgccggat gaagatatct ttcaggtcct cattgaattt ggttgccaac
     7021 ggagcatata catactccga cttgatcggg aagtcggcta tcgaaatggt ctttacctta
     7081 tcataattga tagacgatcc gttaaactta taggaaacag tgcacgcaat gactaccaac
     7141 ggcaagccga acagtagcaa agggcgtatt attttcttaa tccaattcat attcttttat
     7201 ttttctataa agtgtacgct cggaaatatt caagtccttg gccgcactct tccgctttcc
     7261 gtgatgcctt tcaagtgctt tgcgtatcat ttctttttcc acttcgtcca gtgacaaagg
     7321 aggttcttct acatattctt ccgtgtcttg tatgtcgtca tcatccttgc aaaccgcagg
     7381 ctgcatggta tgaatgatcg caggtaccga aggctggtgt gtcgtcacta ccggagtagt
     7441 aaccaccgtt cccacttgtc ctacctgccc cacctgtccg gcacgttccg ccatcaggtt
     7501 gtgcaccatc ttcttcagct ccgccacttc ctggcgcata tcgaacagaa cagaataaag
     7561 aatctcccgt tcgctctcaa agcctttact ctcacgcgtt cccatcagcg cgggaagacg
     7621 ttgcgtattt tgtgcgggaa gataattctg caagatagca gcagagatct ccctgttggt
     7681 ttcaatgata gatatttgct cggtgatgtt cttcaactga cgaacgttgc cgggccacgg
     7741 gtaagccaat aactctttct tcgcatcctc cgtcaactgg atagcaggca tccggtattt
     7801 ctctgcaaag tctgcggaaa acttacggaa caacaaaagt acatcgtcac cacgttcacg
     7861 caaaggcggt atttggatag gcaccgtatt caaccggtaa tataaatctt cacggaaacg
     7921 tccttctgca atcgcttgtg tcagattgac attggtagct gccacaatac gaacatccgt
     7981 cttttgcact ttggacgaac ctacttttat aaactcgcca ctctccaaca cacggagcaa
     8041 acgcgcctgg gtaggcatcg gcaactcccc tacttcatca aggaaaatag taccaccgtc
     8101 ggcttcgcca aagtaccctt tccgttcgcc aatcgcaccg gtaaacgcac ccttctcatg
     8161 cccgaacagt tcggaatcaa tcgtgccctc cggaatagca ccacagttga cagcaatata
     8221 ctgtccgtgc ttcctccggc tatattgatg aataatctgc ggaaaacttt cttttccgac
     8281 tccactttct ccggtaatca gcacagacaa atcggtagga gctacctgaa tggcaacatc
     8341 tatggcgcgc gacaatgctt cagtatttcc aataataccg aaacgctgtt tcacttgttg
     8401 tatctctgct ctcgtcatca ctcgttttta atcttcgtcc actgtatcca gcttcagttt
     8461 atcactatcg tcacgtttct cgtaatactg tttacgcaac ggattggcac gagccacttt
     8521 ttcccgctga cgattacgga acacatcgat ggcaacatag attgcctgac ggaaagaatc
     8581 ttcacaagcc aatcccttgc ctgcaatatc gtatgccgtt ccatgagccg gagaagtacg
     8641 tactaccggc aggcctgccg tatagttcac cccgtcttcc atagccaagg ccttgaacgg
     8701 agccagcccc tgatcgtgat acatcgccag gataccgtca aaatgagtat aattgcccga
     8761 acccataaag ccgtcggccg cataaggacc gtagcaaagg attcctttct cttccatttc
     8821 tttcatggca gggataatca cttcctgctc ttccattccc aacaaaccac cgtctccggc
     8881 atgaggattg agagagagca ccgcaatacg cggagcgccg ataccgaaat cctgtttcag
     8941 acaacgatgg aatatcatca gtttctcctg aatcagttct ttggtaatcg tagtcgcgat
     9001 ctctctgaca gggatatgtg tcgtcaccaa agccacccgg aagtcattct tcatcaaaat
     9061 catcaatgac ttatcaccat tgcccagacg ttcttcgata tattccgtat gtccggggaa
     9121 ggagaactct tccgactgaa tcgtatgttt gttgatcgga gctgttacga taacgtctat
     9181 cagcccttcg cgatattctt cgatggcacg ttccaaagcc ccaagcgcag ctttaccggc
     9241 ttcgggatcg ggtttggaaa attccacttt cacctcatca tccgtacagt tcaccacgct
     9301 caaacggttg taccccgctt cggtagcaga gttgacaatg ctgaaattgg tctgtatatc
     9361 cagcgctttg cgatgataag ccgctacttt cggtgagcca taaatgatcg gagtacatag
     9421 ttccaacatc gtagggtcgg aaaatgtctt aagaatcacc tcatagccca ccccgttaat
     9481 atctccttgg gtgataccta tccttatctt gttatcttcc atgtttttat ttattagttt
     9541 gttccgcttc cttagatgct tctcccaatg gaatctgatt ctgctgaact tcattcggaa
     9601 gtttcagtgt atacagagat gcttccatct ggcgtaccag gttgcgtttc attttatcag
     9661 gtgaataaac aaatatttct gctgttataa ttcgttggtt tttctcgtcc agacgagtat
     9721 gagatacata cgggccaccc ataaagtcgc ccttcatacg ccacaggcca cgtgcttcca
     9781 ttgtgtagct gttctgtaca ttgatcggac ggacatcggt cagcaaacta tcggtcgaca
     9841 tataaacgcc ttccttgaat ccggggatat tggctttcat cacggagtca cgtttgtgca
     9901 caaaatattc tttggtaaac gtatccttgt cagtgtacgg ataagagtac atcacaaagt
     9961 tacggtcggc actacctgtg ttggtagagg cccaaaagaa atcatccccg gtctttgaat
    10021 tagccagttc ggcatccacc cagatgtcgc atccgaacaa actgtccact ttctgcgaaa
    10081 tgaagttact atgcttccct tccaggaacg taatctgacg gttcatttcc gcgcgggtaa
    10141 agaagtcgac aatcgtcttt ttgttctctt ccacaaactt ctcaaactct tcttcgttcg
    10201 gagcctggat agtcaatatc atctgcggat tggcatacac gtccttcgca tatttgaacg
    10261 aggctttcgt atatatatcc tgtatatcta caataataat gttacgtatc aacttcagcg
    10321 tagaatcata atctttcggc gaagtataca taatccggaa agaaggttcc gactgcggca
    10381 aaccgggcat atcagcatcg agcgcatcat gtaaagccct tccggcagca cgatcccaaa
    10441 caccgtgatc tactacaacc aaaagctcgt aagcacgacc actagaggtg tgatttcctt
    10501 tcagaccaca agatgcaacg acaaaggcta ccaaagcgat gcataaaata aaagagtact
    10561 ttttcatgat gttcggtttt atatattaac tttcattatt tttctcctgt ttcgctgtcg
    10621 acagcatacc gcaagcggca aaaatatctt cgcccctgga tgaacggata gtggtgaaaa
    10681 gtccgtgtga cgtcagataa tcacgaaaac gggtcatcgt atccatatcc gccccctcga
    10741 ggtctacccc cggtatggca tgaaaacgaa tcagattcac cctgcaatcc agcccgcgaa
    10801 gaagtttcag caactctttg gcatagacct gcgaatcatt gagcccttta aaaacaatat
    10861 attcaaacga aagtcgacgt tgtttactaa aatcatagtt ttttaacagt tccaccattt
    10921 cggtgattga aaacgccttt tccgccggca ttaattcagc acgctgaacg gtcagcggag
    10981 agtgaaggct gatggcaagg tggcagtcat tttcttcaat aaaacgctgc aatcctttcc
    11041 gtagcccgac tgtagaaagc gtgatacgtt tcggactcca tgcgtaaccg taggtagcgg
    11101 tcagtagttc caatgctttc aatacctcat ccaggttatc gagcggctcg cccattccca
    11161 tcattacgac attagtcagt ttgtcccgtt ccggcagcga atgaatctga ttcatgatct
    11221 ggctggcggt caggttagcg gtatacccct gtttaccggt catacagaac ttacagttca
    11281 tcttgcaacc tacttgtgac gacacgcaca acgttgcccg gtcatcatcc ggaatataaa
    11341 ccgactctac aaaatggttc tcacccactt tataaagata cttcaccgta ccatctacag
    11401 agcgcatttc atctaccgga gcttccgctc ccacctcata gttctgcttg agcaactccc
    11461 ggtgtttcaa tgacaaatta gtcatatcat caatcgaggc taccttcttt tcgtaaagcc
    11521 aggatgcaat ctgcttggca gcaaagccgg gcatacccag tctttttgtc aatgattgaa
    11581 gctctacaag agtcattcct aaaaggggat atttagacat tcttctttct gttgatagtt
    11641 tatatctgca aatgtaagga aataaagtcg atttccgtat agcaggaatg taaaagttaa
    11701 caaaaaaggg aagtatgcct ccgttatgat tcaaccacgc tgatatattg aagtagcttt
    11761 tgcgccattt cagaatcctc gccattcttt ttcacttcat gaccgtacgc ctcacggaaa
    11821 caagccagcg cctcttcccg ttcattacaa aagctgtaca aaacccctaa gttctgacaa
    11881 gccagaatcg tatcttcttc ctcccatccc aaatacttct ttcgcagttc gaactctctg
    11941 aagaaagcct ctttcgccat tggataattc tccaacttca cataagcctg tgctttgtaa
    12001 taatatacca gacaggaagc attagggtca gcatcatcgt gaatatccaa agacgtcgca
    12061 atacgaatca cgttatcata gtctttattc atgtaatact gctgcataat atcacatctc
    12121 aatgcctcat atcggacagt cagttccgcc agacgcggtt tttcgctgaa atacatttca
    12181 tgcagaagag actcacggaa gaataaagta gacgcctgct catcgccacg ttcattcatc
    12241 atccgtttga attccctgca tagataatac aactgtttat gacaagcgac gatctgtttt
    12301 ttattatcta tctgtatagc aatgtccaac gcctgattca tcagcatcca tgcttcatcg
    12361 tatcgtttga tataataaag acatttaccc tgcatacgca aacatttagc cactccaccg
    12421 gacagtctgc cattcaacga ctcgtgcatt tcagctactt tccggaattt ctcggcagca
    12481 ctctcttcct catccttata gtaatcacaa taagccagat attcggaaag ttcaatgact
    12541 tctgcctgac tcttctcgtc agcagaagcc gcatgataat caagcgccct attcagatag
    12601 atcactgctt cattgtattg ctcattgtag taatatgcca gagctagatt tcggcaggtg
    12661 ttggcaatct ccagttccgg agtcggtaca atgttttcct gcatcaccaa tgctttcagg
    12721 aaacagtcgc atgccgtttc gtattcttca ttacgggcat accggcatcc ctcattcatc
    12781 ttcaataccg acttggcaat gagtggcatg gcagcacctt ccatactctt ctcactcaca
    12841 gcagctgccg ccttcgtcag atggaaagaa ctgctcaaga aagtagccat atcattagca
    12901 atgacaggaa ttaaaaaaga atcgatctca tcaaagtcca attcggcata gacttcaggc
    12961 gtaacttcag gattgtcgtt catgatcgcc ttccagctat cttccaacaa agaacgattc
    13021 gtgcgataca gaatctcgaa aatctccaca tcacaaatcc aatccttcaa tatatcccat
    13081 tcttgcatct tatagcattg ataggtaatc tccactttat agcgatacga atcatggtag
    13141 cagaactgtt tcatgcgata gttataatcg gcaaaagtca acggatggga aaggatttct
    13201 tcctcatcca gcagagcgga aataatttca tggcgactat catctataca ttcgtcatct
    13261 tgagcgaaat agcgttcgat cgcctctacc atttgtgtgt caccaatgca atatcgtcct
    13321 cctttgttgg tgagccagct gctcatttcc actctcaact gcgaccaaag tatctgatta
    13381 atgtctgcca tgctcttcac ttcatcttcg gtaaatcctt ctaaagtaag tgaaagcatc
    13441 agaagcgttc ttccaatctc ttcggaacca taatcagccg acaaacgccg tagcacactg
    13501 tcatagaatt gcccaacctc attgagccgg caatatccac gcatatattc attgagagca
    13561 tcgtactgac cgaacgaaac cagctcgttg agcaatacac ttaaacagcg cggttgttta
    13621 gccagcaccc acgaagcaag aatatcttcc tgctgtgcag acaaagcctt ggagtaagta
    13681 gacaaatatt gctttgagaa cgacttggca tccgcctgtg aaaagccatt caactggaaa
    13741 tgagcgca
//
