LOCUS       c00066_gnlPro..        14889 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CDBDLICO_94.
ACCESSION   c00066_gnlPro..
VERSION     c00066_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 11:04:53
            Original ID  :: gnl|Prokka|CDBDLICO_94
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14889
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14889
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[677:4889](-)"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(678..4889)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14889
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14889
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(53..511)
                     /locus_tag="ctg66_1"
                     /transl_table=11
                     /translation="MFKAVFGSIVMSLMPKIQDIVKQDIPFMERLSMILDEYIELFTSN
                     PCLPRFICGEIQRDVNHLLATAKELQFGDALSQVKDSILTAMEDGKLKKVPIHIVFLTV
                     YSLLSYPFLAKNLIVSLFLEDEAAFADFLQEWKQNIINQLQNLLCYEE"
     CDS             complement(678..4889)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_2"
                     /sec_met_domain="HGD-D (E-value: 4.9e-22, bitscore: 70.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.1e-33, bitscore:
                     108.0, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAYKVGLDIGSTTAKMVVLDKDGTTVLFSGYKRHQAKIQECLLG
                     FLYQIKEQLGDIPLSFHITGSVGMGISEKCSLPFVQEVVAATNYVRREHPHTATMIDIG
                     GEDAKVVFFQDGQATDLRMNGNCAGGTGAFIDQMAILLGVSIDELNELALRSNQVYSIA
                     SRCGVFCKTDIQNLIAKNISKENIAASIFHAVAVQTTVTLARGCNIVAPVLLCGGPLTF
                     IPALRKAFANYLNLSQDTDFILPEKGNLIPAWGAALAENNEESIHLSNLIQVIENKLSV
                     TSPFQSDLSPIFDSEEEYRSWKKEKDQYKIQYASLRPGLQEATIGIDSGSTTTKIVVLD
                     NNHRILYSYYHDNNGNPIKTVENGLQKLYEECRRRGTTLRIKGGCSTGYGEDLIKAAFH
                     MDAGIIETIAHYAAAKHISKEVSFILDIGGQDMKAIFVNDGVINRIEINEACSSGCGSF
                     ISTFAQSLDYSVEDFAKAACFSQAPCDLGTRCTVFMNSKVKQVLREGASVADIAAGLSY
                     SVVKNCLYKVLQLKDTEILGDHIVVQGGTMRNDSIVRSLEKLTGKQTFRSNCPELMGAL
                     GCALYAKQIENARVTELNEMLQWAQYTSKQLQCRGCENQCAIMRYTFNSENHYFSGNRC
                     EKVFSNKGSHADKGINTYDKKLELLFDRSADIPQPLFTIGIPRILNMYEEYPFWHTLFT
                     ACGIQVQLSEPSTFSKYETAAGMVMSDNICFPAKLVHSHIRNLTQQNVNRIFMPFVVFE
                     KKDKQQQNSYNCPIVSGYSEVIKSVQEENIPIDAPTITFKDEALLYKQCYEYLKSLGIR
                     DEVCKNAFSRALQEQYAFEEKIATYNQEVLNEGREKHKLIILLAGRPYHSDPLIQHKVS
                     DMIAAMGVYVITDDIVRQQEISLEKTHYLSQWAFTNRILKATKWAAMQEGDIQYMQMTS
                     FGCGPDAFLIDEVRNLLKRYSKNLTLLKIDDVNNIGSIKLRVRSLVESLNFSLKHSQTK
                     DPEPFVSTAPFTKKDKKKKILAPFFTPFISPLIPSIMKVAGYEMETLPLSDTASCDWGL
                     KYSNNEVCYPATLIVGDIVKAFKSGRYDPANTCVAITQTGGQCRASNYISLIKKALIEN
                     GYTNTPVVSLAFGSGIENEQSGFKVNWLKVLPIILASVLYSDCIAKFYYAAVVREKERG
                     QAARLRDLYLDTAQPIIQKNKPEDLLSYSYLAARDFNKICEQRSCHKVGIVGEIFLKFN
                     PFAQKDVTSWLINQKIEVIPPLISDFFMQGFVNLKVRQNQHLQRKLTPDFVIDWLYKKV
                     QKQINKVNEIGKNFNYFTPFESIFEKAEKAKQVISLGTQFGEGWLISGEILSFASQGVN
                     HVISLQPFGCIANHIVEKGIEKRIKSLCPQMNILSLDFDSSVSDVNITNRLLLFIDNIN
                     N"
     CDS             complement(5514..5636)
                     /locus_tag="ctg66_3"
                     /transl_table=11
                     /translation="MSNVTRPIKAKLTEYLKFEDHLQNMIWNHFISESLSDTEN"
     CDS             5974..6210
                     /locus_tag="ctg66_4"
                     /transl_table=11
                     /translation="MKRIVICIVGICSFSFLSAQNSADNVMAERGDSLRISTTTNFSRR
                     LDKFSSSRFYQMTYIGVPLIVGGLIVKREDDHF"
     CDS             6337..7233
                     /locus_tag="ctg66_5"
                     /transl_table=11
                     /translation="MLVSDAFSALLMGGVVNTLKQTTNVERPDGSNKHSFPSGHTATAF
                     MTATMFTKEYGHKSPWVGVGAYSVATATGLMRMANNKHWLSDVLTGAGIGILSTEVGYY
                     FADLIFREKGINRFANENMFDRMDKPSFVSLYLGLNIPLSGYDINEEMEFRTSSGSSAG
                     VEGAYFFNPYVGVGGRFTVSNTLIIVNEERAENNTFDAISLCGGSYFSYPLSSRWLIGS
                     KLLGGYVHYPQLELTDRSVSSRSGFCMGSGVSLTFKAKEYYGIRFFLDYNLLPSHSRNS
                     GEYMNMLTLGSSFMITF"
     CDS             7502..7849
                     /locus_tag="ctg66_6"
                     /transl_table=11
                     /translation="MCAKLPMAADGIVRLSKIEVYPEYLEEYMKYATEVGEVSLRTEPG
                     VLTMYAVSEKENPGRITILETYASQEAYKSHIASEHFQKYKQGTLHMVKTLVLSDQMPL
                     NPANCINNFIQ"
     CDS             7861..8688
                     /locus_tag="ctg66_7"
                     /transl_table=11
                     /translation="MNKLLLFSVFSILTLNVMAQEKIVQTAGRDQLGTFAPKFAELNDD
                     VLFGEVWSRTDKLGLRDRSLVTITSLISMGITDNSLVYHLQSAKKNGITRTEIAEIITH
                     IGFYAGWPKAWAAFNLAKGVWSEDIVGEDAKTAFQREMIFPIGEPNTAYAQYFIGNSYL
                     APVSREQVNISNVTFEPRCRNNWHIHRATKGGGQMLIGVAGRGWYQEEGKPAVEILPGT
                     VIHIPANVKHWHGAAADSWFAHLAFEVSGENTSNEWLEPVTDDEYNKLEQTKR"
     CDS             8917..9480
                     /locus_tag="ctg66_8"
                     /transl_table=11
                     /translation="MKQIIFIFMSLLCFSCSSKAQNQTADTNVQSDKKILVAYFSCTGT
                     TEKAADAIAKTVGGKLYQITPATAYTSADLDWNNKSSRSSIEMTTENSRPELGGEALNL
                     KDYDVIFLGYPIWWNLCPRPVNTFLEKYDFSGKTVIPFATSGGSSITNSVKQLKKLYPK
                     IVWGESRLLNGSVKQAGEWAKGVI"
     CDS             9586..10164
                     /locus_tag="ctg66_9"
                     /transl_table=11
                     /translation="MLLEKLLKEFNFSTNIFNWEEFKLFDQYFERILVSKGTFLIKEGE
                     TERYSYFVFDGILRCWLLNHNGEEQTFWFCKEGTFSMSNISFTLQTRSAFNVQTIVDSV
                     IYRIDKKQVNELYTAIPKVKTVFEDLNAILLNKLLKRNIDLIKYSPEQYYLQMMEEYGI
                     TLNYIPLKDIASYLGITPQALSRIRKRIF"
     CDS             10229..10651
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_10"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_10"
                     /sec_met_domain="Acetyltransf_10 (E-value: 2.9e-18,
                     bitscore: 57.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKIKVTDYPRLMEIWESAVLSTHDFLKEEDFLYYKERLPVYFQ
                     YVNLFGFEQEGILIGFMGIAEGNLEMLFIDNKYRGAGIGKKLITYAIDNLQVTKVDVNE
                     QNVQAVGFYKYMGFNIYKRSNLDGEGKEYPILHMQL"
     CDS             11515..12372
                     /locus_tag="ctg66_11"
                     /transl_table=11
                     /translation="MMTTAKLLLHCPDKPGILAEVTDFITVNKGNIIYLDQYVDHVENI
                     FFMRIEWELKDFLVPQEKIEDYFRTLYGQKYEMDFRLYFSDVKPRMAIFVSKLSHCLFD
                     MLARYTAGEWNVEIPLIISNHPDLQHVAERFGIPFYLFPITKETKEEQERKEMELLAKH
                     KITFIVLARYMQVISEQMINAYPNKIINIHHSFLPAFVGAKPYHAAFQRGVKIIGATSH
                     YVTTELDAGPIIEQDVVRITHKDAIEDLVNKGKDLEKIVLSRAVQKHIERKVLAYKNKT
                     VIFS"
     CDS             12372..12962
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_12"
                     /sec_met_domain="GATase (E-value: 5.9e-24, bitscore: 76.1,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVAVVKYNAGNIRSVDYALKRLGVEAVITADKEELQSADKVIFP
                     GVGEAETTMNHLKATGLDELIKNLRQPVFGICLGMQLMCRHSEEGEVDCLNIFDVDVKR
                     FVPQKHEDKVPHMGWNTIGKTNSKLFEGFTEEEFVYFVHSFYVPTCDFTAATTDYIHPF
                     SAALHKDNFYATQFHPEKSGKTGEKILTNFLNL"
     CDS             12981..13700
                     /locus_tag="ctg66_13"
                     /transl_table=11
                     /translation="MIEIIPAIDIIDGKCVRLSQGDYDSKRVYNENPVEVAKEFEANGV
                     RRLHVVDLDGAASHHVVNYRVLEQIAVRTSLVIDFGGGVKSDEDLKIAFESGAQMVTGG
                     SIAVKDPELFCHWLEIYGSEKIILGADVKEHKIAVNGWKDESACELFPFLENYIDKGIR
                     KVICTDISCDGMLSGPSIDLYKEMLAKFPDLYLMASGGVSKMDDIVALDEAGVPGVIFG
                     KALYEGHITLQDLRIFL"
     CDS             13804..14559
                     /locus_tag="ctg66_14"
                     /transl_table=11
                     /translation="VLAKRIVPCLDIKDGQTVKGTNFVNLRQAGDPVELGRAYSEQGAD
                     ELVFLDITASHEGRKTFTELVKRIAANINIPFTVGGGINELSDVDRLLNAGADKISINS
                     SAIRNPRLVDEIAKNFGSQVCVLAVDAKQTENGWKCYLNGGRIETDKDLFEWTKEAQER
                     GAGEILFTSMNHDGVKAGYANEALAALADQLSIPIIASGGAGCKEHFRDVFLQGKADAA
                     LAASVFHFGEIKIPELKSYLCGEGITIRG"
ORIGIN
        1 taatctgcgt tttattattc attatgacac acctccttat atagtatcta tactattcct
       61 cataacacaa taagttctgc aattggttga tgatgttttg tttccattct tgcaggaagt
      121 cagcaaaagc ggcttcatct tccaagaata aagatactat caggttcttg gcaagaaatg
      181 gatagctcaa taggctgtag acagtcagaa atacaatatg tatcggaacc tttttaagtt
      241 taccgtcttc cattgctgtc agtatactgt ctttcacttg ggataaagca tctccgaact
      301 gaagttcttt tgcagtggca agcaagtggt ttacatcacg ctgtatttct ccgcaaatga
      361 atctgggaag acagggatta cttgtgaaaa gctcaatata ctcatccaga atcatgctta
      421 gtcgctccat aaatgggata tcctgtttta ctatatcctg tattttcggc attaaagaca
      481 tgactatcga gccgaacacg gctttgaaca tcttatcttt ggttctgaaa taataatgta
      541 aagtgggtcg gttgattcct accgttgcag caatatcact catgctggtc tccacaaatc
      601 ctttttctat aaaaagttgt tgggcagttt ttattatttg ctgctctaaa tcgctatgtt
      661 ccgttgtagc cataatttta gttgtttatg ttgtcaataa aaagtaataa tctgtttgtt
      721 atgttcacat cgctgacgct actgtcaaag tctaaagata gtatattcat ttgagggcac
      781 agcgatttta tacgtttttc tattcctttt tctacaatgt gattggcaat gcatccgaaa
      841 ggttgcaagc taatgacatg attgactcct tgggaagcaa aggatagtat ttcaccggat
      901 atcagccaac cctctccaaa ctgggtgccc agggagatga cttgtttagc tttttctgcc
      961 ttttcaaaga ttgattcgaa cggcgtgaag taattgaaat ttttgccgat ttcattcact
     1021 ttattaatct gcttctggac tttcttgtat aaccagtcga taacaaagtc gggagtgagt
     1081 tttcgctgca agtgttggtt ctgtctcact ttcaggttga caaatccctg catgaagaaa
     1141 tcacttatca gtggcggaat cacttcgatc ttctggttga tgagccatga ggtgacgtcc
     1201 ttttgagcaa aagggttgaa cttcaggaat atttccccaa caatacctac tttgtgacag
     1261 gatctctgtt cacagatttt gttgaagtct ctggcagcga gatatgagta gctcaacaag
     1321 tcctccggtt tatttttctg gatgatgggc tgtgctgtat ccagataaag atcgcgcaga
     1381 cgggcggcct gtccccgttc tttctcacga acgacagctg cataatagaa tttggcaatg
     1441 caatcactgt ataacacaga cgcaagtatg attggtaaaa ccttgagcca gtttacctta
     1501 aaaccggatt gctcattttc gataccactg ccgaaagcaa gtgataccac cggtgtattg
     1561 gtgtatccat tctcaatcaa tgcctttttt atcagtgaaa tatagttgct ggcacgacat
     1621 tgtccaccgg tttgcgtgat ggcaacgcac gtattggcag gatcataacg tccgctttta
     1681 aaggctttta ctatgtcgcc gacaatcaat gttgccggat aacatacttc attattggag
     1741 tatttcaatc cccagtcgca tgatgcggtg tcgctcaacg gtaaagtttc catttcatat
     1801 ccggccactt tcatgatgga cggaatgagt ggtgagatga aaggcgtaaa aaatggagcg
     1861 aggattttct tctttttgtc tttcttggtg aaaggagcag ttgaaacaaa tggctcggga
     1921 tctttcgttt gagaatgttt caaactgaaa ttcaagcttt ccaccaacga gcggactcgt
     1981 aatttgatgg agccgatatt attaacatcg tctatcttga gcaaagtaag attcttgctg
     2041 tatcgcttca gtaagttacg tacttcatct ataagaaaag catccggacc gcagccaaaa
     2101 gaagtcatct gcatatattg tatgtcaccc tcttgcattg ccgcccactt ggttgctttc
     2161 agaatacggt tggtaaatgc ccattgagag aggtaatgag ttttttccaa tgaaatctcc
     2221 tgctgacgga caatatcatc agttatcaca taaactccca tcgcagcaat catgtccgaa
     2281 accttgtgct gtatcagtgg atcgctatgg taagggcgtc cggcgagtaa gataatcagt
     2341 ttgtgttttt cccgtccctc gttcagaact tcctgattat aggtagcaat tttttcttcg
     2401 aaagcatatt gttcctgtaa tgcgcgtgag aaggcatttt tgcatacctc atccctgata
     2461 cccaaagatt tcagatattc atagcattgt ttatacagca atgcttcatc tttgaaggtg
     2521 atagtcggag catctatcgg tatattctct tcctgtacac ttttgatgac ttccgaataa
     2581 ccggaaacga tggggcaatt atagctgttt tgctgttgct tatccttttt ctcgaaaacg
     2641 acgaacggca taaatatccg gttgacgttt tgttgcgtca gattgcggat atgactgtgc
     2701 acaagtttgg cagggaagca gatgttatca gacatcacca tgccggcagc agtctcgtat
     2761 ttgctgaatg tagagggttc cgacaactgt acctgaatgc cgcaagcagt aaataaggta
     2821 tgccagaaag ggtattcctc atacatgttc agaatacgtg gaatacctat ggtgaatagg
     2881 ggttgtggaa tgtctgcgct ccggtcgaat aataattcca gctttttatc atacgtattg
     2941 atgcctttgt ccgcatggct tcctttattg gaaaacacct tctcacaccg gttgccggag
     3001 aagtaatggt tttcactgtt gaacgtatat cgcatgatgg cgcactggtt ctcgcacccc
     3061 cggcattgaa gttgcttgga agtatattgt gcccattgga gcatctcgtt cagctccgtc
     3121 acccgggcat tttcgatttg tttggcatat agggcacaac caagagcacc catcaattca
     3181 ggacagttac tgcggaaggt ttgtttcccg gtcagctttt ccagacttcg tacgatggaa
     3241 tcattacgca tggttcctcc ctgcacgaca atatggtcgc caagtatctc cgtgtctttt
     3301 aattgcagaa ccttatacag gcagttttta acaacggaat aagataatcc ggcagctata
     3361 tccgctacgg acgctccttc ccgaagtacc tgttttactt tggagttcat gaagactgtg
     3421 caacgtgtac ccagatcaca tggtgcttgc gaaaaacaag ctgctttggc aaagtcctcc
     3481 acactgtaat ccagcgattg cgcaaatgtg ctgataaaag aaccgcaacc ggaggaacag
     3541 gcttcattga tttcgattct gttgattact ccgtcgttca caaagatggc tttcatatcc
     3601 tgccctccaa tatccaggat aaaagaaact tctttgctga tatgtttggc agcagcataa
     3661 tgagcgatgg tttcaatgat tcccgcatcc atgtggaaag ccgcttttat cagatcttct
     3721 ccgtaaccgg tagaacatcc tccttttatg cgcagggtag ttcctcgtct ccggcattct
     3781 tcatatagtt tctgcaagcc gttctctact gtttttatag ggtttccgtt gttgtcgtga
     3841 taataggagt aaaggatacg atgattgttg tcgagtacta cgattttggt ggtagtagag
     3901 ccggagtcta tgccgatagt tgcttcctgt aatccgggac gcagactggc atattgaatt
     3961 ttatactggt ctttttcttt tttccatgac cgatattctt cctcactgtc gaatatagga
     4021 gaaagatcac tctggaaagg tgaggtaaca cttagtttgt tttctattac ctgtatcagg
     4081 ttggagagat gaatactttc ttcattgttc tctgccaatg ctgctcccca ggcagggatc
     4141 agatttcctt tttccggtaa tatgaaatct gtatcttgtg acagattcag atagttggca
     4201 aatgctttcc gaagggccgg aataaaagtc aatgggccac cgcagagtaa taccggagct
     4261 acgatattgc aaccgcgtgc aagtgtgaca gtggtctgta cggctactgc atggaaaatg
     4321 gaggctgcta tattttcttt agatatattt ttggctatca gattctgtat gtccgttttg
     4381 cagaatactc cgcagcgtga agcgatagag tatacctgat tggaacgaag tgctagttca
     4441 ttcaattcgt cgatggagac tccaagcaga atagccatct ggtcaatgaa agccccggtt
     4501 ccgccggcgc aatttccatt catgcgcagg tctgtagcct gtccgtcctg aaagaaaaca
     4561 actttcgcat cttctcctcc aatatcgatc atagtggctg tgtgcggatg ctcccggcgc
     4621 acatagtttg ttgcagctac aacctcttgc acaaacggca gagagcattt ctctgaaatt
     4681 cccattccaa cagagcccgt aatatggaaa gataaaggaa tatcacccaa ctgttccttt
     4741 atttgataaa gaaatccgag taaacattct tgtatttttg cctgatgcct tttgtatccg
     4801 gaaaacaaga ctgtagttcc atctttgtcc aatactacca tcttggcggt agtagagcct
     4861 atatctaaac ccactttata tgcattcata taccaaacat cttaaattag acctcgtgtt
     4921 tgacacctgt gtcagacgca aatgtatgta aaaatatggt agatacggca aatcgtaatt
     4981 gaagttttgg gtttaattaa cgaattggga aaaaagaaag atggaatgtg agggaggaaa
     5041 acgattgtgt aaataaagaa gtaaatgaat gattgtatgc ttatattact tgtaaggttg
     5101 tagcagatct tttatggtga atcttagaaa tcttgtttac tctatttttg acaaaaggaa
     5161 acgtggcttt taataaaccc ggattctgtt tataataaac tttttgatag ttttagtaaa
     5221 acggtattcg agtttattat aaactattgt agaacagttt tagaatcaga cgagagattt
     5281 taagctgaat tataaacaaa atggggcaat aatcattcga ctattgcccc atatcgtata
     5341 ggagtggtat tgtaaaatac caggttattt atgatttatg tatgattatt tcttactatt
     5401 ttcatgttgc ttatactttt tcttttctca aagatacaac ataaaaagtc ctttgtcaag
     5461 agtctgatga gaaaagtatc ttatcggttt taaaaataga gtccgcgtgc catttagttt
     5521 tctgtatccg agagggattc gctaataaaa tgattccaaa tcatattttg caggtgatct
     5581 tcgaatttga gatattctgt aagtttggct tttatcggac gtgtcacatt tgacatataa
     5641 gtttcacagc tgtcatgcaa caaacatccc aactgtatat ggttggaaag tcctcgtgtt
     5701 ttagcctctt tgcagcacgc gatagaatgt tgggcaacag aataaaagaa acgggtatga
     5761 ccgtttgcac gacagatcaa agacaaggca tgagcgatgt ctttcatatc aattttttca
     5821 ggaacaggat ggatggggtc gaaatgcttc cccgtaaaag ttgtaatgta actcataact
     5881 atagaattta tagtcatatt tttgtaaatc ttcaaacttt ctacaaagtt gcctgttatc
     5941 tttgtatcct aattcaaaag aaattacgat agcatgaaaa ggattgtaat atgcattgtt
     6001 ggcatttgta gcttttcttt cttatcggct caaaattcgg cagataatgt aatggcagaa
     6061 agaggggata gtttgcgtat ctctacaaca accaatttta gtagaaggct tgataaattc
     6121 tcatcttccc gtttctatca gatgacgtat atcggcgttc cgttaattgt tggtggcttg
     6181 attgtaaaaa gggaggacga tcatttttga ggtttacgta acgaatatct gccccgtttc
     6241 aatcgtcatt tggatgatta tatgcaatat gcccctgctg cggtgatgct tggtatgaaa
     6301 gtagctggag tacaaagtcg cagttcatgg ggtagaatgc tcgtttccga cgctttttct
     6361 gcactgctga tgggtggtgt ggtaaatact ttgaagcaaa cgacgaatgt cgagcgtccg
     6421 gatggctcaa acaaacactc ttttccatcc ggacatacgg ctacggcatt tatgactgct
     6481 accatgttta ctaaggaata cggacataaa agtccgtggg taggtgtcgg agcatatagt
     6541 gtggctactg caaccggtct tatgcggatg gcaaacaaca agcattggtt aagtgatgta
     6601 ttgacgggtg caggaatcgg aatattgtca acggaagtgg ggtattactt tgctgatctg
     6661 atattcaggg aaaaagggat caataggttt gcgaatgaaa atatgttcga caggatggac
     6721 aagccttcat ttgtcagttt gtatctcggg ttgaatattc cgttgagtgg ttatgatatc
     6781 aacgaagaaa tggagttccg tacttcatca ggcagttcgg ccggtgtgga gggggcctat
     6841 ttttttaatc cgtatgtagg cgttggagga cgattcacag tttccaatac tttgattatt
     6901 gtcaatgaag aacgggcaga gaataacacc tttgatgcga tatcgctttg cggaggaagc
     6961 tatttttcat atccgttgtc ttcacgatgg ctgataggca gtaaacttct gggtggatac
     7021 gtgcattatc cacaattgga attaactgac cggtcggttt cttcaagaag tggtttctgc
     7081 atgggaagtg gggtttcctt gacgttcaaa gcaaaggaat attatggaat ccgttttttt
     7141 ctcgattata acttgcttcc gtcacatagc agaaacagtg gtgagtatat gaatatgctt
     7201 actttggggt catcatttat gattacgttc taaatcgtag tatatttaat tcttttattg
     7261 gcaatataat tcatttcatt cgaattatgt acggttcttt attgcagaat cggggatttg
     7321 ggtacaaaaa tccgtaattg atatacaatt ccattcgttt tatcgcagta aatttgcaat
     7381 cagaagttta acaatgaaaa gatagaagat ggtgataaaa acaattctaa gtgttttgtc
     7441 tttattcgtt atgttatcat gcagtatgac agggaaaaag gatataaaac agcagcctgg
     7501 tatgtgcgcc aaattaccta tggcggctga cggtattgtg cggctatcaa aaatcgaggt
     7561 ttatccggag tatcttgaag aatatatgaa atatgcgacc gaagtgggtg aagtctcctt
     7621 gcgtactgaa ccgggagtgc tgactatgta tgccgtcagc gaaaaagaga atcctggcag
     7681 gataactatt cttgaaactt acgcgagtca ggaggcttat aaatctcata ttgcatcgga
     7741 gcattttcaa aagtacaagc aaggaacgct gcacatggtt aagactctcg tactctctga
     7801 ccaaatgccg cttaaccccg caaattgcat taataacttc attcaataaa cgaaatgatt
     7861 atgaataaac tccttttatt ttcagtattt agtattttaa cactcaatgt tatggcacaa
     7921 gaaaagatag tacagacggc aggacgcgac cagttaggaa cgtttgcccc taagtttgcg
     7981 gaacttaatg acgatgttct ctttggagaa gtttggagcc gcactgacaa actcggtctg
     8041 cgtgaccgca gtttagtaac cattacctcc cttatcagta tgggaatcac ggacaattcg
     8101 ctcgtttatc atcttcagtc ggcgaagaag aacggcatca cccgcacgga gatcgcagag
     8161 attatcactc atataggttt ctatgcaggt tggccgaaag cgtgggcagc gttcaatttg
     8221 gcaaaaggag tatggtctga agatattgtt ggtgaggatg ccaaaacagc tttccagcgt
     8281 gagatgattt tccctattgg tgaacccaat acagcctatg cacagtattt tattggtaac
     8341 agttatcttg ctccggtttc gcgcgagcag gtgaatatct ctaacgttac ttttgaacca
     8401 cgttgccgca ataactggca tattcaccgt gcaacgaaag gtggcggaca gatgcttatc
     8461 ggtgtagccg gtcgaggctg gtatcaggaa gaaggtaaac cggcggtaga gattctgcct
     8521 ggtacggtta tccatattcc tgccaatgtg aaacactggc acggagctgc tgccgacagt
     8581 tggtttgctc atctggcttt cgaagtttcc ggtgaaaaca cttccaatga gtggcttgag
     8641 ccggtcacag atgacgagta taacaaactc gaacagacta aacgatgatt tttgctaatc
     8701 ctgctttatc ttttgaaagg aaataatatg actaccgagg aattttaagg aatatgtaaa
     8761 gacgcgcaaa gcgcttaata cagaagaaat acatcgtttg atggacgata tgggcaatta
     8821 tcaaagtaat ggaagaatga aaacgcctgt ggggttactc catcgtgata atgtctaaac
     8881 taattaatga taagaaatat ttaaaatcaa aataaaatga aacagattat attcatattt
     8941 atgagtctcc tttgctttag ctgctcatca aaagcgcaga atcagacagc ggatactaat
     9001 gtacagtccg ataagaaaat cctggttgcc tatttctctt gtactggaac tacagaaaaa
     9061 gccgccgatg ccattgcaaa aacggttggc ggcaaacttt atcagataac tcccgctaca
     9121 gcctatacct cggcagatct cgactggaac aacaagagta gccgtagttc aattgaaatg
     9181 acgactgaaa attcacgtcc ggaattgggg ggagaagcgc ttaatctgaa agattacgac
     9241 gtgatattcc ttggttaccc gatatggtgg aatttatgtc cgcgtccggt caatacattc
     9301 cttgagaaat atgatttctc cggtaaaacc gttattccat ttgctacttc cggaggaagc
     9361 tcaataacta atagtgtaaa acaactcaag aaactttatc caaaaatcgt atggggagaa
     9421 agccgattgt tgaacggaag tgtcaagcag gccggagagt gggcgaaagg agtaatataa
     9481 aaatggctac tgaaaatata ttcactaaat atgagaagtt aaatagggcg gaagtaatag
     9541 tgaatatatt aaatgagtaa gtatattacg aatcatattt agattatgct tttagaaaaa
     9601 ctacttaaag aatttaattt tagtactaat atttttaatt gggaggagtt taagttattc
     9661 gaccaatatt ttgaacgaat attagttagt aaaggtacat ttttgattaa ggaaggagaa
     9721 acagagaggt atagttattt cgtttttgat ggaatattac gctgttggct tttaaatcat
     9781 aacggggaag aacaaacttt ctggttttgt aaagagggta cgttttcaat gtcaaacata
     9841 tcttttacat tacaaactag gtctgcattt aatgtgcaaa caattgtaga tagtgttatt
     9901 taccgaatag acaagaagca agtaaatgaa ctatataccg ctatccctaa agtaaaaact
     9961 gtatttgaag atttaaatgc tatattgttg aataaacttt tgaaaagaaa tatcgacttg
    10021 attaaatatt ctcctgaaca gtattatcta cagatgatgg aagaatatgg tattacatta
    10081 aactatatac cattaaaaga tatagcttct tatttgggta tcacaccgca agcactaagc
    10141 agaatccgta aacgtatttt ttaacttggg ttcagtgttt tgaatgtata agtaacgaac
    10201 tttgcggctt taaattgcaa ttacaagtat gattagaaaa attaaagtta cggattatcc
    10261 acgtttgatg gaaatttggg aaagtgcagt attgagtaca catgattttc ttaaagagga
    10321 agatttttta tattataagg aacgacttcc ggtatatttt cagtatgtta atctattcgg
    10381 atttgaacaa gagggaatct taatcggatt tatgggaatt gcagaaggaa atcttgaaat
    10441 gttatttatt gacaataagt atcgaggcgc aggaatcgga aaaaaattaa taacttatgc
    10501 catagataat ttgcaagtaa ctaaagttga tgtgaatgag caaaatgttc aagctgtcgg
    10561 tttttataaa tatatgggtt ttaacatata taaaaggtcg aatttggacg gagaaggtaa
    10621 ggaatatcct attttacaca tgcagttgta gtctctgttc aattataaac agatgcttag
    10681 tataggtacc tttaattgaa gatgtaatgt tacatttgaa taaaatgatt ggttaaaaaa
    10741 tcattgtaga gtttgaatgg gcacatctat cgcctactta aactctgttt taaatgaact
    10801 gaagaaaaag aaaaaagctc tgaatttctt gaatttcaga gctttgcttt aatttactat
    10861 ttgctttcgc ggtgcgtacg ggactcgaac ccgtgacccc atgcgtgaca ggcatgtatt
    10921 ctaaccaact gaactaacgc accaaatttt aattggatta actcatttct atttctctct
    10981 gcttcttagt gaaagaagcg gtgcgtacgg gactcgaacc cgtgacccca tgcgtgacag
    11041 gcatgtattc taaccaactg aactaacgca ccagaatttc aatttattaa tctgcatctc
    11101 tctcgattgc gggtgcaaag gtagttgttt tttgtaaacc tgcaagcgtt ttgagaaaag
    11161 tttttttcaa gaaaaaacaa gaaaaatgct tagtgtctca ttttgagtac ttttgtaatg
    11221 aaaaaaaata ttcgtttttc ttctcttcgg atagtgacgg tatctgatcg ttatagtgac
    11281 gctatcacga tggaataccg tcactatccg aaggcaatgg catcactatc ctaaagtttg
    11341 tcattctttt cattgaaaat aactctcgat atctttctat ctgtaagaaa tcaccgtttt
    11401 tatatcaact ttctgcttga ataattcgta attttgcaat aaatcgttat ttttgcggac
    11461 taaaattaga aaggtagaaa ataatctgcc tagaatcgtt aattagtaga aagaatgatg
    11521 acaacagcca aactgttatt gcactgtccc gacaaaccgg gaatcctagc ggaagtgaca
    11581 gactttatta cggtaaacaa aggaaatatt atctatctgg atcagtatgt agatcatgta
    11641 gagaacatct tcttcatgcg tattgaatgg gaactgaaag attttctggt tccacaggaa
    11701 aaaattgaag attatttcag aacactctac gggcaaaaat atgaaatgga ttttcgtctt
    11761 tatttctctg atgtaaaacc acgtatggct attttcgtat ccaagctgtc acactgtctt
    11821 ttcgatatgt tagcccggta tacggcagga gagtggaatg tagagatacc tcttattata
    11881 agtaatcatc cggatttgca gcacgtagca gaacgtttcg gaattccttt ctatctgttc
    11941 cctatcacca aggagacgaa agaagaacag gagcgcaaag agatggaatt gcttgccaaa
    12001 cataagatta catttattgt attggcacgc tatatgcagg tgatctccga acagatgatt
    12061 aatgcttatc cgaataagat tatcaatatt catcattctt tccttcctgc gtttgtaggg
    12121 gcgaagcctt atcacgcagc tttccagaga ggggtgaaaa ttattggtgc aactagtcat
    12181 tatgtaacga cagagctgga tgccggaccg attattgaac aggatgtagt gcgcattact
    12241 cataaagatg ctattgaaga cctcgtaaat aaaggaaagg atttggaaaa aatcgttctt
    12301 tcgcgtgcag tgcagaagca catcgagcgc aaagttttag cttataaaaa taaaacagta
    12361 atatttagct gatgaaagta gcagttgtaa aatacaatgc cggcaatatt cgttctgtgg
    12421 attatgcttt aaagcggttg ggggtagaag cggtgattac tgctgataaa gaagaactcc
    12481 aatcggccga taaagttatt tttcccggag tgggagaggc ggaaactacc atgaaccact
    12541 tgaaggcaac gggactggac gaactgatta agaatctccg tcagcctgta tttggaattt
    12601 gtctcggcat gcagttgatg tgccggcatt ccgaagaagg agaagtcgat tgtttgaata
    12661 tctttgatgt ggatgtgaaa cgttttgtcc cgcagaaaca tgaggataaa gtgccgcaca
    12721 tgggatggaa caccattgga aaaacgaata gcaaattgtt tgaagggttc accgaagaag
    12781 agtttgtcta ttttgtgcat agcttctatg tgccgacctg cgactttact gctgctacaa
    12841 ctgactatat tcacccgttc agtgctgcgc tccataaaga taacttttat gctacccagt
    12901 tccatccgga aaaaagtggt aagacaggag agaagattct gacaaacttt ttaaacctct
    12961 aagatacaaa tagtaaatag atgatagaaa ttattccagc cattgatatt attgatggaa
    13021 agtgcgtacg cctttcccag ggagattacg atagtaaaag ggtgtataat gagaacccgg
    13081 tggaagttgc aaaggagttt gaagcgaacg gtgttcgcag gctccatgtg gtagacttgg
    13141 acggtgctgc ttctcatcat gtcgttaact atcgggtgtt ggaacagatt gctgtacgca
    13201 cttctcttgt catagatttt ggtggaggag taaagagtga tgaagatttg aaaattgctt
    13261 ttgagagcgg tgcgcagatg gtaaccggag gaagcattgc agtgaaagat ccggaattat
    13321 tctgtcattg gctggaaata tacggcagtg agaagattat tttgggggca gatgtaaaag
    13381 aacataagat agccgtcaat ggttggaaag atgaaagtgc ctgtgaactt tttccatttc
    13441 tcgaaaatta tatagataaa ggtatacgaa aagtaatctg tacggatatt agctgtgacg
    13501 gaatgttgag tggtccttct atcgatttgt ataaagagat gctggcaaaa ttccctgacc
    13561 tttatctgat ggctagtggc ggggtgagca agatggatga tattgttgcc ttggatgagg
    13621 ccggtgttcc cggagttatt ttcggtaagg cattatacga aggacatatc accttacaag
    13681 atttgagaat ctttctataa tgagcgtatc ggaataaata agataccttt attataagga
    13741 agataagaat cgagcttcag gaatatagat tataaattgt tgaacaataa ataaaatagg
    13801 attgtgttag caaaaagaat agtaccttgt ttggatataa aagacggaca aaccgtgaaa
    13861 ggaacgaatt ttgtcaactt gcgtcaagct ggtgatccgg tggagctagg ccgtgcttac
    13921 agtgaacagg gagcagatga acttgttttc ctggacatta ctgcaagcca tgaaggacgt
    13981 aagactttta cggaattggt aaaacggatt gctgctaata tcaatatccc atttaccgta
    14041 ggtggtggaa tcaatgaatt aagtgatgta gaccgtctgc tgaatgcagg ggcagataag
    14101 atttctatca attcttccgc tatccgtaat ccccggttgg ttgacgagat agcaaagaat
    14161 ttcggctcac aagtttgtgt gttggctgta gatgccaaac agaccgaaaa cggttggaaa
    14221 tgttacctga acggaggacg catcgaaacg gataaagatc tgttcgagtg gactaaagaa
    14281 gcacaggaac gcggagcagg agaaatactc ttcacaagca tgaatcacga tggtgtaaaa
    14341 gccggttatg caaatgaagc acttgccgct ttagcggatc aactctccat tcccatcata
    14401 gcttcaggag gtgcgggctg taaggagcac ttccgtgatg tctttttaca gggaaaggca
    14461 gatgctgcat tggctgccag tgtttttcac ttcggagaaa ttaaaattcc cgaattaaaa
    14521 tcgtatcttt gcggcgaagg aattaccatc agggggtgag gcaccccggc cgggttttcc
    14581 tgcggatgga ttatatagtc agataaatat aggaactgtc tgcaaaagaa ttccgtaggc
    14641 gaataggtag taattgtaaa ttggaatagt aattagaact tatataaaaa tggaattgga
    14701 tttcgataaa atgaacggac tcgttccggc tatcatacag gacaacgaga cacgtaaggt
    14761 cttgatgctg ggtttcatga ataaagaagc ttatgataaa acggtggaaa ccggaaaagt
    14821 tacattcttt agccgtacga agaatcgttt atggacaaaa ggcgaagaaa gcggtaactt
    14881 ccttcatgt
//
