LOCUS       gnlProkkaJHDJLGCA_83   11896 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JHDJLGCA_83.
ACCESSION   gnlProkkaJHDJLGCA_83
VERSION     gnlProkkaJHDJLGCA_83
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 05:26:11
            Original ID  :: gnl|Prokka|JHDJLGCA_83
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11896
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11896
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2582:6896]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2583..6896
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11896
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11896
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             2..1360
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 72.3;
                     E-value: 4.8e-22)"
                     /gene_kind="transport"
                     /locus_tag="ctg37_1"
                     /transl_table=11
                     /translation="MRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIR
                     GAVYRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIM
                     DGTSPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGL
                     KEAASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRR
                     SPGYQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANAS
                     EKKRMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVI
                     SIPKNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTK
                     VKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             1371..2519
                     /locus_tag="ctg37_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             2583..3302
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.5e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             3323..4624
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1e-12, bitscore:
                     40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             4641..5765
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.7e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5775..6896
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg37_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.1e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5865..6872
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg37_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg37_6_Aminotran_5.1"
                     /locus_tag="ctg37_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6893..7036
                     /locus_tag="ctg37_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             7239..8723
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.2e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             8677..9936
                     /locus_tag="ctg37_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             9945..10694
                     /locus_tag="ctg37_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             10694..11734
                     /locus_tag="ctg37_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 tgtccgtcag aatggtgagg aatacgaagt caacacagtc aaagatatag attacaacat
       61 ttataaaatg cgtaacggtg acgtagtaac cgccgaagcc atccttaacc gcttcacaaa
      121 caaactggaa atccgtggcg ctgtctatcg tcccggtatc taccagctca gcggtaaact
      181 gaacacgatc cgcgaacttg tccatgaagc tcagggtctg accggtgacg ctttcctgaa
      241 tcgtgccgtc ctctatcgcc agcgtgaaga cctgaccagt gaagttgttc agatagacat
      301 taagtctatc atggacggca cttccccaaa ccttgcccta atgaagaatg acatcctcta
      361 cattccaagt atccatgacc tggaagaccg gggtaatgtc acagttcacg gtgaggttgc
      421 ccaccctgat tcctatcctt atgcggataa catgacactt gaggatctga tcattcaggc
      481 cggtggcttg aaagaagccg cctctactgt ccgtattgat atatcgagac gaatcaagaa
      541 tcctcgtagt actgcggata atgatacgat tggtcagatg tataccttct ctttaaagga
      601 tggttttgta atagatggtc agcccggttt tatccttgag ccttatgatc aggtttatgt
      661 ccgtcgcagt ccgggctatc aggcacaaca gaatgtagcc attgaaggtg aaatcctttt
      721 cggaggaaat tacgccatga ccagccgtga ggaacgtctt tccgatttag tgaataaagc
      781 cggtggtccg accaattatg cctatctgcg tggtgcgaaa ctgacccgtg tggctaacgc
      841 tagtgaaaag aaacgtatgg gtgatgtaat tcgccttatg agcaggcaat tgggcgaagc
      901 catgattgac tctttgggta ttcgtgttga agatactttt acggttggaa tagatttgga
      961 aaaagccttg agcaatccta aaagtaatgc cgatcttgtc ttacgtgaag gtgatgtgat
     1021 ctccatacct aagaatacta atactgtaac tatcaatggt gctgtcatgg ttccgaatac
     1081 ggtttcttat atgaagggaa agaatgtgga ttattacctg aatcaggccg gtggctgttc
     1141 tgataatgca aggaagagta agaagttcat tgtttacatg aatggtcagg tgacgaaggt
     1201 taagggtagt ggtaagaaac agattgagcc ggggtgtgag attattgtgc ctggtaaggc
     1261 taagaagaaa gggaacatag ctaatatttt aggttatgct acttccttca gttctttggg
     1321 aatgatgatt gcttctattg ctaatttgat aaagaaataa atgacctatt atgattgaaa
     1381 agcaatctta tcaagaaccg ttttctgaag tggataaaag gaaagatgat gaaatggaaa
     1441 tagacttgat ggctattttt tataagatta ttactgttcg tggagtacta tgcaaagctg
     1501 ctggagtggg agtaataatt gctatagtgg tggcattgag cattcccaag caatatacag
     1561 taaaggttac cctttctcct gaaatgggta atgcgaaggg aagtaatggt ttagccggac
     1621 ttgctgcctc gtttttggga gatggggctc taatagggga aagcacagat gccttgaacg
     1681 cttctctttc agcagatatt gtttcttcaa ctcctttttt attggaactt ttagaaatgg
     1741 aagtctccgt ttctaaaaag gatgataaaa tgactttggg gtcttatctc gatgaagagt
     1801 catctccttg gtgggattat cttataggtt ttccgggcat agtaatagga ggagttaaat
     1861 cattattcgg agaagatacg gttcctgcca gtggagggcg gcaaggaact atcgaattga
     1921 cgaaagaagt aaatgagaag attaattttc ttaaaaagaa gattagtgca tccattgata
     1981 agaaaaccgc cataacgagc attacggtca ccttacaaaa tccgcagatc actgcggtta
     2041 tagcagattc tgtcgttcat aaattacagg aatatattat tgggtatcga acttcaaaag
     2101 taaaagaaga ctgtgcgtat ttggaacggt tgtttaaaga acgtcagcag gaatattatg
     2161 ctgctcaaag aaaatatgcg gattatgtag acgcccatga taatgtggtt cttcaaagtg
     2221 tacgtgctga gcaggagcgt ttacagaacg acatgagttt ggcttatcag atatatagtc
     2281 aggttgctaa tcagttgcag gtatccagag ccaaagtaca ggaggaaaag ccagtctttg
     2341 cagtagttga gcctgccgtt gtacctttga aaccttcagg tatgggactc aaaatttata
     2401 ttttattatt tgtgttcctg tccgtatctg gtactctcgt gtgggtgttt tttggcaaaa
     2461 gtctgctggc tagcttgaga aaagaactga aaaataagga gatagaacag gataaatgat
     2521 gctaaaacgt cgtttacaac attcttacat caattaaatt cacttactat attattaaac
     2581 gaatgatacg tacagctatg ataatggctg cgggcatggg aacccgtttt ggccaatata
     2641 cagaattgat acctaaaggg ttcgtcaaag tgggaggtat tccaatgata gttcgttcta
     2701 ttgatacttt gttatcatgt gacattgagc gaattgtaat cggtacagga tataaacaag
     2761 aagtttatga agaattgaag acagactatc ctatgcttga aacctgtttt agtcctcgtt
     2821 atgctgaaac aaatagtatg tatactttat ataatacgcg ggagattctg ggcaatgatg
     2881 attttttatt gttagagtca gatttgattt ttgagaaaca agcaataatg agcttattgg
     2941 agtgtcctgc ggcagatgca atgctaataa ctccagtgac aaagtttcaa gatcagtatt
     3001 atgtggaaca tgatgataat tttcgccttt cttcatgttc tgtcaataag aataaactaa
     3061 acgctaaagg cgaattggtc ggcatccata aactatccgg ttccttttac aaaataatgt
     3121 gtgctgatta tgcgagtatt gttgatgaac aacccaattt gggatatgag tatgaattac
     3181 tacgaatatc ttgttctcaa tctcctgttt atgtgcataa agtagaaggg ctgaaatggt
     3241 atgaaatcga tgacatatca gatttggaat atgcagagaa atatattgtt ccgtattgtt
     3301 aattaaaata atatatcaaa ttatgagtaa gacagtttat attgggatga ctgcggatat
     3361 tatgcatcca ggacttatcc gcattattaa tgaggctact aaatacggtg atgttataat
     3421 tggtcttctt acagataaag ctattgcgga gcataaacgc cttccttatc tgacctatga
     3481 acaacgaaaa gaggtagttc agaatattaa aggcgtatgt aaagttgttc ctcaagaaga
     3541 atggagctat gttgagaatc tcaaacgcat taaacctgac tatataattc atggtgacga
     3601 ctggaaaacc gggcctttac gtgaagaacg tgtgcgcgta tttgaagtga tgaatgaaca
     3661 gggaggaaag gttatcgaaa ttccatatac tttgggaatt aattcatctt ctttggataa
     3721 agatattaag gctataggta caacccctga tgtacgttta aaatcacttc gtcgtttgat
     3781 aaatgccaaa cccgtagttc gtattttgga agctcatgat ggactatgtg gcttgataat
     3841 tgaaaatcag gaaatattaa aaggggataa gagggaagta tttgacggaa tgtggtctag
     3901 tagccttacg gattcaacca gtaaaggtaa acctgatatt gaggcggttg atttaactac
     3961 ccgattgcaa gatttgaata atattctgga gtgtactact aaacctatta tttttgatgg
     4021 agatacaggt ggtaaaattg aacatttcgt atttacagta cgcactttag aacgtcatgg
     4081 aatttcagct ataataattg aagataaagt tggattaaaa aagaattcat tgtttggtac
     4141 agatgttatt caaactcaag atacaatcga aggtttctgt aataagatca aagcaggaaa
     4201 ggcatctcag attactgatg attttatgat tatcgctcgt attgagagcc ttatagcggg
     4261 aaagccggta agtgatgctt tagagagagc ttttgcatat gtccaagcgg gagcggacgg
     4321 tattatgata catagcaaaa ataagtcggg tgaagatata aaagaatttt gtttggcgtt
     4381 tcgaaaacag tatgctcatg tacctatcgt ggttgtgcct actacatatg atcatattta
     4441 tgagtctgaa ttgtgtgatt ggggtgtgaa tataattatt tatgctaatc atatgcttcg
     4501 tgccgcttat cctgctatga tgaatgtcgc aaagataata ttagagaatg aacgtgcttt
     4561 agaggtgcgc gaactgtgta tgcccataaa agaaatattg gaactgattc caggtactaa
     4621 ataaaaagag gaatatcatt atgttaagcg tagaaaaagt ttatgaaacg tttctgagtc
     4681 atgacgttga tttttttaca ggagttccag actcattact aaaaaatatt tgtgcctata
     4741 tcacagacca tacttcacgt gagaaacata tcatagctgc taatgaaggt gcggctgtag
     4801 gaattgcttc aggttattat atggcatcag gtaaggttcc tgtggtttat atgcaaaatt
     4861 ccggcttggg taatactgtt aatcctctgc tgtctcttgc agatgaacaa gtatacagtt
     4921 ttccaatgct tttgatgatt ggctggcgtg gtgaaccggg aacaaaagat gaacctcagc
     4981 ataaaaaaca gggtgaggta actttagatt tgttgaaagc aatgcggatt ccttatataa
     5041 ttcttgattc aaatgagaat gatgcattta ttcagctcca tgatatcata caatcagcaa
     5101 aaactaagaa tattcctcat gcaataatta ttcggaaaga tgtttttggc aaatataaac
     5161 ttcaaaaaga gttcggatgt aattatcctt tatctcgtga ggatgctttg caaatagttg
     5221 tggattatct gcctgaaaat tcagtggtcg tttctactac tggcaagctt tctcgtgagt
     5281 tatttgaata tcgagaaatg aaagagcaag gtcatgaaca tgattttctc acggtaggct
     5341 ctatgggaca tagttcatca atctctttgg gtattgctat agcaaagcaa gatagacctg
     5401 tttattgctt ggatggtgat ggagcattta ttatgcattt aggggcaatt agtaacattg
     5461 gcgatttatc tcctaaaaac tattatcata ttttgtttaa caatggtgct cacgagtctg
     5521 taggaggaca gcctacttta ggatttagtt tagatattcc ggctattgtc cgggggagcg
     5581 gatataagca tacttatact gtttgtacaa aagttgaaat tgaagaagca atgaagcagc
     5641 ttccaaagtt atgtggtcct gttttgttgg aaataaaggt taaaatagat tctcgggaga
     5701 atttgggacg tcccacgact actcctatag agaataagga gcattttatg gattttttaa
     5761 aataaatata ttcgatgaaa atagaaagaa aaatattatt aaatcctggg cctgccacta
     5821 ctactgacag tgtaaaaatg gcacaagttg ttccggatat ttgtcctcgc gagaaagaat
     5881 tcgcaggtat gatgaaacaa cttcgggacg atttggtcag agttgctcat gggaatttgg
     5941 aaaaacatac cgctgtatta ttttgtggct caggaaccat caatattgat atatgtctaa
     6001 attctcttct tcctgaagac aaaagggtgc ttatagtgaa taatggggca tatagtaccc
     6061 gtgctgtaga agtgtgtcaa tattatggtt tgcctcatat taatttggaa ttttccgttt
     6121 acgaacgtcc tgatttatcg gtggtggaaa atgtgttgca agaaaatcct gatatagcta
     6181 tggtttatac tactcatcac gagacgggta caggaattct gaaccctatt cgcgagatgg
     6241 gcgctatagc tcataaatat caggctaaat ttgtcgtcga tactacttct tctttgggca
     6301 tgattccttt tgatatagag aaagataatg tggatttttg tatggcatct gctcaaaaag
     6361 gacttcaagc gatgacaggt ctttctttta ttataggcaa tgaggaacag attaagtttt
     6421 caaaaaaata tcccaagcgt tcttactatt gtaatcttta tttgcagtat gagaattttg
     6481 agagaacagg tgaaatgcat tttactccac cggtacaaac tatttacgcc actcgtcagg
     6541 cattaaatga atattttgaa gtgggtgaag aagctaagtt tgcccgtcac aaaagagttt
     6601 ttgaggctat tcattcaggt ataaatgaaa ttggtcttaa aagtgtaata aagcgtgaat
     6661 ggcagtcagg actggttgtc tcagttcaat acccagaaga tcccaactgg gattttgaga
     6721 aaatacatga ttattgttat gagcgtggat ttacgattta tccaggtaag atatcaactg
     6781 aggatacttt tagaatctgt gctttaggag agatagaagt agatgatatt gagaacttct
     6841 ttaaagtact aaaagctgca ttaaatcatt ataacgtcac attaccgatg tcatgattgc
     6901 agaaatatta ttgaagattc gtcattttta tttttccctt cgtggtatac acttccatcc
     6961 ggaaagtgtt atttctggag tgcctattcg tagctttcgc ttagtaggca aatatggcaa
     7021 tattaatttg aggtgatgca ttaggagttc tttattctta taaaaaggca tcggtagtta
     7081 taggagataa tgtttgtgta gggtaatttg cttttagtgg gagagaccat attagaattg
     7141 cggtaagggg cgaagaagat aataaccaat tagtgagaat attggaaaaa tataattgat
     7201 atcggtaaat gtagttgttt ttatactgta tttaagtaat ggaaaatcta aagcagaaaa
     7261 ctgtatcagg aataatgtgg agcgctatag aacgtttctc tttacaagga gtacagttta
     7321 taattcaaat aatattagct cgtttgttac taccatcgga ttatggtatg atcgggatgt
     7381 tagctatttt tcttcaagtc gctcaagtat ttatagatag cggttttaca aatgctttaa
     7441 tccagaaaaa agatagaact gaagaggatt ttgccactgt cttttatttt aatattcttg
     7501 tcgcagtatt attctatggt atattgtttt tttcggcttc tttgattgca gacttttata
     7561 atatgccgac tttagttctt gtaattcgtt ttatagcatt gtcgttgata ataaatgctt
     7621 tatcggctat tcacagaacg aaattaatta tttctgtaaa ctttaaaact caatctaaaa
     7681 tttcattagg tgcagctttt atatcaggcg tgattggaat atggatggct tatgtcggtt
     7741 gcggggtttg ggctttagtt tggcaaactc tcttaaatag tataattttg acaattttgt
     7801 tttactgttt agttcattgg aaacctttac atactttctc caaaagttct tttgaaagat
     7861 tattcaattt cggatctaaa ttattgatct caagtcttat caatacagta tatcgtaatc
     7921 tgtataccat tgtaatagga aaaaagtttt ctgttgtaga gcttggttac tatacaagag
     7981 cagaacaatt tgctattttt ccttccaata atttaaatgc tttagtttct agagtagcgt
     8041 atcctatttt aagttccatt caagatgatg ataaatgttt aacaaacgca tatcgaaatt
     8101 atatcagatt atcctcatat ataatttttc ctttaatggt aggtttactt gttttggcta
     8161 atcctattat tagtctattg ttaacagata aatggtctgg ggttgttatt cttttacaga
     8221 tattatgttt ggattggatg tttgatcatt tgagccaaat taatttgaat ttattatggg
     8281 ttaaaggaag atctgatctg tcgttacgtc ttgaaataat aaaaaagacg attgctatat
     8341 tcattctttt tgtgtcaatt ccatttgggc ttgaggtgat gtgttggggt agagttattt
     8401 actctctgat agcgacatat ttgaatacat attatactaa ttctcttatt gatttgacct
     8461 taaagttgca agttaaagat gtatttccaa gtttaatact ctctttcata atggggggga
     8521 tcgtttttat atgtatttct ttctttgaaa ctgatatagt aaaaattgtg attggatgta
     8581 ttactgggat gtccttctat attttacttt cttttctttt taagctagat tctttttttt
     8641 gtattttaac attgatcatt aaaactaaaa acatagatga aaatattaaa aaagattttt
     8701 caagtaatag taaagataat taaccattgt gtgccagttg atagtagatc attgtatttt
     8761 attcctcatc ctaattgtag aacagataaa tatgatatta taaattattc gtcagataat
     8821 gttctcgttc tgttaaatta tttgctaaaa aaagatagtg ctgaatatta taaaatatat
     8881 gttgaaattt atgattcttc tcgtatttca gaatatcaag aatatattta tggcataaat
     8941 cctaatatta ggtgtacttt tttatgtgca tgtgttggac gttttttctt taataaagta
     9001 tcttttaagg atatgttgta tgcctttttt tgtttttgta gagcaagtaa atgttttaca
     9061 gctacttttt attatgattt ttcatttaaa aaacgctctc aacagattat ttgtttgggg
     9121 tattatactc cattcaaaga tgattatcat atgggagatc attcttatga taaatttcgt
     9181 aatacaacat gtaactcatt tgattactct attgctactt cttgtttaag tgctagaata
     9241 atttcaatag attgtggaat ctcatatgat aaattcaaag tcttaggatt tcccagaaat
     9301 gatttgttga tatcgaaaaa taattgcaat gttattaaaa gagaaatttc gaaatttgcg
     9361 ggatatgatg taactaaata tatagtttat actccaactt ttcgtgatta tgagactgtt
     9421 actgaaggta atttgcgttc aatactcgga tatgttgatt gtgatttgtt gaagttatcg
     9481 aaaatactat tgaagtttaa tgcggcttta attcttaaat tacatccttt gcagaataaa
     9541 acagtcttaa aaaaagattt acccaaaggt atacttgttt ttgaacaaac atataaatat
     9601 ggattgtatg atcttttgtc attttcagat ggaatgatta ctgattatac ttctacctat
     9661 tttgattttt tattggtaaa taagccagtc atatttaatt tctacgatat tgaagaatat
     9721 cgtagagtaa gaggtttctc atttgagcca atagaatttt tttgtgcagg tgatattgtt
     9781 tacaattata atgaattgat agatgctgtg atgggacttc tggctgggaa agatattcat
     9841 gctgaacatc gacgtcatat ttctttattg atgaatcaat ttcaagatga taattcaaca
     9901 aagagaatat gtgacatatt tttaaatgaa atataataaa taaaatgaat tatgcatttg
     9961 tggtgcaggc acgtttaggt tctacacgtt tgcctggaaa aatattgaaa cctttctatg
    10021 gtaatcaatc gattcttgac ttaatggttc ataagctttc tgctatatcg aatattccag
    10081 taattattgc tacaacaaat tctgttatca atgaacctat tgaaaagaag gcacttgcat
    10141 taggggtaaa gtgcttcaga ggtgaggaga atgatgtttt aaaacgattc attgatgttg
    10201 ctgaatattt tgatatacag ggtatattcc gaatatgttc tgataatcca tttttagatg
    10261 tacatgcggc aaggcaattg gtcgaaatag caatgaaatc ttgtaacgat tatataagtt
    10321 ttgatattga tggtactcca tcaattaaaa ctcatttcgg tttttgggga gaatttgtaa
    10381 cgcttgatgc gctgaagcga gttataggat ttactgatga tttattgtat cgtgaacatg
    10441 ttactaatta tatatatagt catcctgaac tttttaatat tcaatggatt tcaggatctc
    10501 cagtcgtgtc aaaacatcat aatattcgac tcacgattga tacgttagaa gatttttctg
    10561 tagcacagag aatatatagg gatttacaag aaaaaagagt ggaaatatcg atagaagtga
    10621 ttgtagacta tgttcgaaga catgcagaat acattcaact gatgaaacaa caaataaaaa
    10681 aaaattctaa ataatgaaga atacttatat tattggtgaa atagggcaga atcataatgg
    10741 ttctgttgac ttggctaagt tgattattga attaatctca cgacctgtac atgaggatgt
    10801 ttttggtatg gatttcatgc caatgaatgc tgttaaaatg actaaaagag atttatcaga
    10861 agaattggct gtttctcaaa tgaatcaaat atatgacaat cctaattctt ttgggcgtac
    10921 ttatggtgaa catcgtgctt ttcttgagct tgatgatcaa gcgcattttg agatttataa
    10981 atatgctaag tcattaggat tagattttat cgagacgtta tgtgccaaag gatgtctgtc
    11041 tttgcttaaa ctgttcacac cggataggct aaaagttgct agtcgtgatt tgactaactt
    11101 accattgctt gaagcattag cagaaactca tattcctatt atattatcga caggaatggc
    11161 tggtcaaaga gaacttgaca atgcattaga tgtgataacg agatatcata gtaatatagc
    11221 tattctacat tgtgtatctc agtatccaac tcatccaaat aatttgaatc tacgtacaat
    11281 aacatatttg aagaagcatt acaataagtt tgagataggt ttttctgatc atacaatagg
    11341 tatttctgct gctacagctg ctgtagcgat gggagcggaa attatagaaa agcatgtaac
    11401 aattgatcgg catatgaaag gaacagacca gcttggctct ttaggtccag atggggttaa
    11461 tcgtatgatt cgagatattc gcatagcaga gtgttggctt ggtactgaag atctttatat
    11521 agaaaaaggg gtggagaagt ctaagataaa acttgaacgt tctattgcca ctcgaaaata
    11581 tattccagca ggtagtatta ttcaagagtc ggacattcat ttactgagtc ctggtgatgg
    11641 ttataaatgg atagataaaa aaaatgtaat tggtcatttt gctaaacaag atatatcagc
    11701 gaatgaaata atatatcctg attttattga atagatatat tcctactgca acttgtatta
    11761 cggtatagag tactgcctgc tataagctaa gtagtgatta ataaataagg gtaaaatact
    11821 aaaaaaatga aagagataaa gcttatactt acagatattg atggcgtttg gactgatggc
    11881 ggaatgtttt atgatc
//
