LOCUS       gnlProkkaCGFNCKLL_186  14008 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGFNCKLL_186.
ACCESSION   gnlProkkaCGFNCKLL_186
VERSION     gnlProkkaCGFNCKLL_186
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 04:46:12
            Original ID  :: gnl|Prokka|CGFNCKLL_186
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14008
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14008
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3657:4008]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3658..4008
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14008
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14008
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             667..2178
                     /locus_tag="ctg156_1"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWEVLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHALTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             2251..3318
                     /locus_tag="ctg156_2"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETMYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKAAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKIPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             3355..3639
                     /locus_tag="ctg156_3"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(3658..4008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg156_4"
                     /sec_met_domain="PqqD_RRE (E-value: 1e-10, bitscore: 32.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-17, bitscore: 54.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQYEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVV"
     CDS             complement(4106..5494)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg156_5"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(5743..6138)
                     /locus_tag="ctg156_6"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPAAETPAPAAE"
     CDS             complement(6145..6918)
                     /locus_tag="ctg156_7"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQSAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(6924..7451)
                     /locus_tag="ctg156_8"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(7438..8679)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg156_9"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(8689..9783)
                     /locus_tag="ctg156_10"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQTNFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(9788..10828)
                     /locus_tag="ctg156_11"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             complement(10847..11881)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg156_12"
                     /sec_met_domain="PF04055 (E-value: 4.4e-18, bitscore: 57.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYPLLGMTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDD
                     MTNLSLKHRELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGYTANLTASQIMNQIHSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALELLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAE
                     LMPAEKAFSITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRV
                     NLIRFHAIPGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEK
                     NNES"
ORIGIN
        1 atgtgatgca cattatctat ctccaaagat aacattttta tcggaaacgg caaataatca
       61 aaggcttaat caggggaggg ggcgtatcaa aagtttgttc aagaaggtat gaagatgaag
      121 gaaaccgtaa ccacacatga ggcatatagc ttaatagtgc ctaatgtcgg cactatacga
      181 caattttgaa gttgggttat taatagacaa ctgaagtcag ctacttagtc aactccagtc
      241 gaccatgtag ccgacagtag tcatctaagt agccaactac agttggctaa tatcatgcca
      301 actatttcaa tccggtcttc aatcatattc gttctcctat gtctttccat attgaagaaa
      361 cacctaagct tttgttttga ccgggcttct ttcttaaggg cgcgaacagt gtgaaagatg
      421 tgaagggtta aaaagagaac cttaaatcac aacaaacatc tgtcacacta caacttacgt
      481 gtccgtgaaa cttgtgaaag gtacaaaatg attattttta ataaatcaaa ccaccacgaa
      541 tttgattcat ttccctgccc ccaacaagtc atctccttat gattaacaag ttttcttccc
      601 acaacaaacg ggaaaagtca gaagaatcat gtacatttgt aatccgaaaa ctaaaagaac
      661 atcgcaatga aaatatttcc aagcagcagt atcaagaaat tggacgctta taccattgag
      721 aacgaaccta ttgcatcaat cgatctgatg gaacgtgcag caaccgtatt aacaaaagcc
      781 atcacagaca gatggaatac ggaaacgccg gtcactatct ttgccggacc ggggaataat
      841 ggcggagacg ctctcgccgt agcccgcatg atggctgaaa aaggatataa aatcgaggta
      901 tttctcttca acacaaaagg agaactttca cccgactgcc agaccaataa agaactggta
      961 gaaatgatgg aagaagtaaa attccacgag atcagtaccc aattcgtacc tcccgccctg
     1021 acgcccgacc atctggtaat cgacggatta ttcggttcag gtctgaacaa accgttgagc
     1081 ggcggattcg ctgccgtagt gaaatacatc aattcctccc ctgccatggt agtagccatc
     1141 gacattcctt ccggactgat gggagaagaa aatacattca acgtaaaagc taatattatc
     1201 cgtgccgacg taactttcag tctgcaactg ccgaagctcg cctttctttt cgcagagaac
     1261 acggaatttg tcggagaatg ggaagtgctg gatatccaat tgagcgaaga cggtattgaa
     1321 gagatggaga ctaactacga aatgttggaa atagagcaaa tccgttcact catcaagcca
     1381 cgcaaacagt ttgcccacaa agggaacttc ggccatgcac tattgattgc cggttcaaaa
     1441 ggaatggcag gagcctctgt tctcgctgcc cgcgcctgcc tccgttcggg agtagggttg
     1501 ctgactgtcc atgcgccaat gtgcaacaac gacatcttgc aaacctccat acccgaagca
     1561 atcgtagaaa ccgacatcaa cgaaacctgt tttgccgtac ctaccgacac ggacgactat
     1621 caagcagtcg gcatcggccc aggactggga cgaaacgagg aaacggaagc tgctttattg
     1681 gagcaactgg aacattgcca gactcctgtt gtggtggatg ccgacgcact taatatcctt
     1741 gccaaccacc gccatgccct tacccacctg ccgaagggtt ccatcctcac cccgcatccg
     1801 aaagaactgg aacgtctgac cggcaaatgc caggactctt acgaacgtct gatgaaggct
     1861 tgcgaattgg ctcgtgccgc ccatgttcac attattttaa aaggagccta ctccgccatc
     1921 atcaccccag aaggtaaatg cttcttcaac ccaaccggaa atccgggaat ggcaaccgga
     1981 ggtagcggtg acgtactgac cggagtaatc ctggcactgc ttgcccaagg ttaccccacc
     2041 gaggaagccg ctaaaatcgg cacttacatt cacggattgg cgggcgatgt cgctcaaaag
     2101 aagcaaggaa tgatcggaat gatcgcaagc gatattatca cctgtctgcc gacagcatgg
     2161 cgacttgtaa gcgaataaaa gttaagaact tacagttttt tcaataactt cattaacttt
     2221 gttttcaaaa ccagttaaaa agaaccgaat atgaaaaagt tgattatagc agcaggacta
     2281 cttatgacaa cgtccgccta tgcacaaacc gaagtactga caggggttac ccgaggaaaa
     2341 gactatggag tggtttacag tcttcccaaa acccaaatag aacttgaaat aaaagccaac
     2401 aaagtcaact atactccggg agaattcagc aaatatgctg atcgttacct gcgactgacc
     2461 aacgtctccg ccgaccctga agagtactgg gaactggcta gcgtaaaagt gaaatccgta
     2521 ggtgtgccca acagcgaaac tatgtatttc gtaaaattga aggataagac agtagcaccg
     2581 ctcatggaac tgacagagga tggcattgtg aaaacgatca atgttcctta cagcaatagc
     2641 agtgtaggta aaaaagctgc tcccgccccc gcagtcctcc aaaagaaagc gaatcctcgc
     2701 gaattcctga ccgaagagat tctgatggct agttctaccg ccaagatggc cgagctggtg
     2761 gctaaagaaa tctataatat ccgcgaaagc aaaaatgcct tattgcgcgg acaagctgat
     2821 aatatgcctt cagatggggc acagcttaag attatgctcg acaatctgaa tgcacaggaa
     2881 gaagccatga cacaaatgtt ctccggcacc tgcaacaaag aagaaagaac attcactgtc
     2941 cgccttaccc ctgacaagga attcaacaat gaagttgcct tccgcttctc gaagaagtta
     3001 ggtgtagttg ccaacaatga tttggcagga actccgtttt atatcagtct gaaagacctg
     3061 aaatcggtca aaataccaca ggaagacggt aagaagaaga aagatttgga tggaatcgcc
     3121 tacaacgtac ccggacaagc tatggttaca ttgaccgacg gcaaaaagaa actttacgaa
     3181 ggtgaacttc ctattactca atttggtgtg atagaatatc tggctccggt tttgttcaac
     3241 aagaattcta ccatcaaagt ttattttgat ccgaatacgg gaggattgct caaagtggac
     3301 agagaagaag ggaaatagaa aaacgaggaa gtgaacttct aaaaaacaaa gaatatggtt
     3361 ggtgaaggac atgcattcga catgatacgc cgaataaaag agggacggga agcttcccgc
     3421 ctacgtcgtg aacgtgctaa cgataagttg aagcatctaa accgtgcaaa cgaaccttat
     3481 ccactaccca acaccacccc cgaagaaatg gaacgtatca tccacgactc ggagaaaaag
     3541 aaagagaaag acagcaatta ttttgtttgg ggaacgctta ttatcatggg ggtcctgata
     3601 gcaattgccg tcatactttg ggctgtattt atcaaataaa taataataag ttcctattta
     3661 tacgactggt atcaccagtt ttataaatcc atctttctgc atttgagaaa gataagccga
     3721 tacacgcgac tcgtagccct cttcatattg aaagtggtct gcgagttttt ctataatctc
     3781 acgaacattg cgttttccat ctatcagttc ccatacagcc gtaccgtgtt cttccaattt
     3841 cacatgaagt tctttcgaca ttcctttcgg cacaaggaag cgttgcatcc acggatattt
     3901 aaaacgggga aaggagagca caattgtctc cccttccctt tctgctgtaa tatgttcact
     3961 gcgacaggga atgacctcta acaggttgat tttctctttg gcagccatac ttcttatttt
     4021 ttatttcaga gtattcatac tgatactctt ctgtttacac cttgatacaa aattcctttg
     4081 tcactttagg tattgaattt cctagttact tttggatatt cgcctcttcc agaccgtatc
     4141 ccttcttctt gttctctgcc tttaacatca aagccacaat cagagcaagc acaccaaaga
     4201 gagcaaaaat agccatcggc aacgtgtagt cataagtctg tgcaccgtct actaccggac
     4261 ctttgcaata agtattcaac acccatccga tcaacaaagg aacacccatc aatccccagt
     4321 tctgtaccca gaaaatcaat gcgtatgctg tacccaactg tttttccgga ataatcttcg
     4381 gaacagacgg ccacatagct gaaggcacca acgagaaggc aaatcccaat ataatcatga
     4441 tgatagtagc aaaccaccat atattcagta taggcagagc aaacatcgta tgcacaaaaa
     4501 taagcatcac tgatccgatt atcatcaacg tagctccctt accgatacgg tcataaagcg
     4561 agccgaacaa cggagtcagg ataatcgcac caatcggcaa caatccggga atcgttcccg
     4621 ccaacttcgg atctacatta tacttctgca ccatcaagtc ggcagcatac ttgataaagg
     4681 ggaatacagc cgagtagaac aatacacata gtaatgcaat caaccagaat cccttattcg
     4741 taatgatata cacaatatct ttcatacgga acggttcttc cggttccaat ccctctgcat
     4801 ccaaagaagc atccaacttc ttatcataga aagtataaag gaagaaagca atcgtaccca
     4861 cgcacaacat aatcagacaa aacaaaatcg gagcaggaat attggtatgg aatgtgccac
     4921 tctcatccgt agatccgaag aagtcggcca aaggaaccgt gagcaccatt gccagagttg
     4981 ttccgatacg tgccgtagcc atttcaagtc ccatagccaa tgccatttcc ttacccttga
     5041 accattttac gataattttg gaaactgtga taccggcaat ttccacacct acaccgaaga
     5101 tagcataccc caatgcggcc agggttacct gtgttttgaa tccaaagagc atggcacctt
     5161 ccggaaaagt agtagaaatc gcatagtatt tcaatccaca accaaacacc atcaataagc
     5221 aagcccccat tccggtgaaa cgaactccca tcttatccaa aatgatacca ccgaaaatca
     5281 gcatcaatag gaatacatta aaccacccgt aagcgcttgt gaagaaacca taatcaagac
     5341 tgtcccatag tagttctttc tcaagcatgg gttttagagg agacattacg tcggtgagga
     5401 aatagccgca tagcatagta aatgcgacca atgctagaac actccatcgg agtacggcgg
     5461 agtcattcaa tttctgtttc aaatgttctg tcattgttat atttaaaaaa gtagttaata
     5521 atcttcatac gaccaacaaa ggtagttaaa tctcgtttgt ttctatcaaa aagagattgt
     5581 ttttacaaga aaaagttaag tgcggattac actgaccacg cggaagattg aaaatccgtg
     5641 taatctgcgt aatccgcact taaatatcaa agaaatgcag catccgtctg caccttccca
     5701 ttaatggttt taccccaaag tcttacctga cgacagagtg aattactctg ctgcaggagc
     5761 aggagtttca gcagccggtg ccggagtttc tgtagcaggt gcattggtag caggagcttc
     5821 agtttgcggc gcagccgtac ctgcgggtaa gttatacggg ttagtctgtt gttctttctg
     5881 tgcctgttcc aacactgcgt ctttagcaac agcagagcga ggaactacat aagcagtagc
     5941 aatgctcatt accaccatga agatagctaa gccccatgtt gctttttcca gaaaatctgt
     6001 agtcttgcgc acgcccatga tggcgttaga tgaagagaaa ccagaagcaa gtccgcctcc
     6061 ttttgagttc tgaatcagca cgatgaaaca catcaacaag gctgcaataa ccattaagat
     6121 aacgaataat aagtacattt ttagttattt tgaattagcg ttaataatca atttctccaa
     6181 aaatctgatt tggtctgcaa agtaagcatt tttttttgga tatttcaagc ttaatttttt
     6241 aattatttca agagcttttg aatatcgttg ctgtttaaca tagatttttg ccaaagtttc
     6301 cgtaaaacag ctgtcatctt cctcttcttc cttcatcgtt tcttcttcgg taagttcgtc
     6361 cgaagaggtt ggcgaagatg gcatttcttc tcttaaaggt ttcttgcaga ggggagagtc
     6421 gctctcgctc ttttctataa agtcgtcaat cagttcgtag cctttgagtt tgggcgtttc
     6481 ttcggccgac tgttccgtgg ccggagtctc ctccaaaaga taagaggtat aatccatcga
     6541 atagtcgaag ctggtgcggg cagtcacctc ttcgggtact gtggacaaga aagcgtcgat
     6601 caatgctaat gtgcggtcta cggacggttc gtctttcagt acctccgtga gaggtactcc
     6661 ctttttccgt gcctgcacat catagcggtc accttcaatc aaccggaaca actgccgtct
     6721 gtctgcaatg taaagaactg ctttccgcag ttctccaccg aaactaatat catggagaat
     6781 atacagattc ttcagataca gcagacgaag tgactgaaaa tacggatacc tcgcaagaag
     6841 attgcgcagt tcgtacaaag tatccctatt cagcgtctcg ggatgctgaa tccattgttg
     6901 aaagttaaca gaagtcattt atattaccag tttgctacag ttgcattaaa aatttggtcg
     6961 gtgatctctt tagacatttc agcaatcaat ccgtcctgta cggcagtcag caactggcta
     7021 gagtcgtagg tacggaacgc agaaaactgt tgttcaaagt cttcggcatg attggtgttg
     7081 ttgacaaaac gtacattgac ggtaatagtc aacttcgtct ccgaagaata accgtcggca
     7141 gatactgcct ggttgtactg attgtatcct gtgatttctc cgtcaatctg caagtccgca
     7201 ttctgattcg gcttgagcag ttgcagacgg gtctgccgga tgaagatatc tttcaggtcc
     7261 tcattgaatt tggttgccaa cggagcatat acatactccg acttgatcgg gaagtcggct
     7321 atcgaaatgg tctttacctt atcataattg atagacgatc cgttaaactt ataggaaaca
     7381 gtgcacgcaa tgactaccaa cggcaagccg aacagtaaca aagggcgtat tattttctta
     7441 atccaattca tattctttta tttttctata aagtgtacgc tcggaaatat tcaagtcctt
     7501 ggccgcactc ttccgctttc catgatgcct ctcaagtgcc ttgcgtatca tttctttctc
     7561 cacttcatcc agtgacaaag gagattcttc tacatattct tccgtgtctt gtatgtcatc
     7621 atcatccttg caaaccgtag gctgcatggt gtgaatgata gcaggtaccg aaggttgatg
     7681 cgccgtcact accggagtag taaccaccgt tcccatttgt cctacctgcc ccacctgtcc
     7741 ggcacgttcc gccatcaggt tgtgcaccat cttcttcagc tccgccactt cctggcgcat
     7801 atcgaacaga acagaataaa gaatctcccg ttcgctctca aagcctttac tctcacgcgt
     7861 tcccatcagc gcgggaagac gttgcgtatt ttgtgcggga agataattct gcaagatagc
     7921 agcagagatc tccctattgg tttcaatgat agatatttgc tcggtgatat tcttcaactg
     7981 acgcacgttt cctggccacg ggtaagccaa caactctttc ttcgcatcct ccgtcaactg
     8041 aatagcaggc atccggtatt tctctgcaaa gtctgcggaa aacttacgga acaacaggag
     8101 cacatcgtca ccacgttcac gcaaaggcgg tatctggata ggcaccgtat tcaaccggta
     8161 atataaatct tcacggaaac gtccttctgc aatcgcttgt gtcagattga cgttggtagc
     8221 cgccaccaca cgcacatccg ttttttgtac tttggacgaa cctactttca taaactcgcc
     8281 actctccagt acacggagca aacgtgcctg ggtagacatc ggcaactccc ctacttcatc
     8341 aagaaaaata gtaccgccgt cagcttcgcc aaagtaccct ttccgttcgc caatcgcacc
     8401 ggtaaacgca cctttctcat gtccgaacag ttcggaatca atcgtaccct ccggaatagc
     8461 accacagttg acagcaatat actgcccgtg cttcctccgg ctatattgat gaataatctg
     8521 cggaaaactt tctttcccga ctccactttc tccggtaatc agcacagaca aatcggtagg
     8581 agctacctga atggcaacat ctatggcgcg cgacaatgct tcagtatttc caataatacc
     8641 gaaacgctgt ttcacttgtt gtatctctgc tttcgtcatc actcgttttt aatcttcgtc
     8701 tactgtatcc agcttcagtt tatcactatc gtcacgtttc tcgtaatact gtttacgcaa
     8761 cggattggca cgagccactt tttcccgctg acgattacgg aacacgtcga tggcaacata
     8821 gattgcctga cggaaagaat cttcacaagc cactccctta cctgcaatat cgtatgccgt
     8881 tccatgagcc ggagaagtac gtactaccgg cagtcctgcc gtatagttca ccccgtcttc
     8941 catagccaag gccttgaacg gagccagccc ctgatcgtga tacatcgcca ggataccgtc
     9001 aaaatgagta taattgcctg aacccataaa gccgtcggcc gcataaggac cgtagcaaag
     9061 gattcctttc tcttccattt ctttcatggc agggataatc acttcctgct cttccattcc
     9121 caacaaacca ccgtctccgg catgaggatt gagagagagc accgcaatac gcggagcgcc
     9181 gataccgaaa tcctgtttca gacaacgatg gaatatcatc agtttctcct gaatcagctc
     9241 tttggtaatc gtagtcgcaa tctctctgac agggatatgt gtcgtcacca aagccacccg
     9301 gaagtcattc ttcatcaaaa tcatcaatga cttatcacca ttgcccagac gttcttcgat
     9361 atattccgta tgtccgggga aggagaactc ttccgactga atcgtatgtt tgttgatcgg
     9421 agctgttacg ataacgtcta tcaatccttc gcgatattct tcgatggcac gttccaaagc
     9481 ccccaacgca gctttaccgg cttcgggatc gggtttggaa aattccactt tcacctcatc
     9541 atccgtacag ttcacaacgc tcaaacggtt gtaccccgct tcggtagcag agttgacaat
     9601 gctgaaattg gtctgtatat ccagcgcttt gcgatgataa gccgctactt tcggtgagcc
     9661 ataaatgatc ggagtacata gttccaacat cgtagggtcg gaaaatgtct taagaatcac
     9721 ctcatagccc accccgttaa tatctccttg ggtgatacct atccttatct tgttatcttc
     9781 catgttttta tttattagtt tgttccgctt ccttagatgc ttctcccaat ggaatctgct
     9841 tctgctgaac ttcattcgga agtttcagtg tatacagaga tgcttccatc tggcgtacca
     9901 ggttgcgttt cattttatca ggtgaataaa caaatatttc tgctgtaata attcgttggt
     9961 ttttctcgtc cagacgagta tgagacacat acggaccacc cataaagtcg cccttcatac
    10021 gccacaggcc acgtgcttcc attgtgtagc tgttctgtac attgatcgga cggacatcgg
    10081 tcagcaaact atcggtcgac atataaacgc cttccttgaa tccggggata ttggctttca
    10141 tcacggagtc acgtttgtgc acaaaatatt ctttggtaaa cgtatccttg tcagtgtacg
    10201 gataagagta catcacaaag ttacggtcgg cagtacctgt gttggtagaa gcccagaaga
    10261 aatcatcccc ggtctttgaa ttagccagtt cggcatccac ccagatgtcg catccgaaca
    10321 aactgtccac tttctgcgaa atgaaattac tgtgtttccc ttccaggaac gtaatctgac
    10381 ggttcatttc cgcacgggta aagaagtcga caatcgtctt tttgttctct tccacaaact
    10441 tctcaaactc ttcttcgttc ggagcctgga tagtcaatat catctgcgga ttggcataca
    10501 cgtccttcgc atatttgaac gaggctttcg tatatatatc ctgtatatct acaataataa
    10561 tgttacgtat caacttcagc gtagaatcat aatctttcgg tgaagtatac ataatccgga
    10621 aagaaggttc cgactgcggc aaaccgggca tatcagcatc gagcgcatca tgtaaagccc
    10681 ttccggcagc acgatcccaa acaccgtgat ctactacaac caaaagctcg taagcacgac
    10741 cactagaggt gtgatttcct ttcagaccac aagatgcaac gacaaaggct accaaagcga
    10801 tgcataaaat aaaagagtac tttttcatga tgttcggttt tatatattaa ctttcattat
    10861 ttttctcctg tttcgctgtc gacagcatac cgcaagcggc aaaaatatct tcgcctctgg
    10921 atgaacggat agtggtgaaa agtccgtgtg acgtcagata atcacgaaaa cgggtcatcg
    10981 tatccatatc cgccccctca aggtctaccc ccggtatggc atgaaaacga atcagattca
    11041 ccctgcaatc cagcccgcga agaagtttca gcaactcttt ggcatagacc tgcgaatcat
    11101 tgagcccttt aaaaacaata tattcaaacg aaagtcgacg ttgtttacta aaatcatagt
    11161 tttttaacag ttccaccatt tcggtgattg aaaacgcctt ttccgccggc attaattcag
    11221 cacgctgaac ggtcagcgga gagtgaaggc tgatggcaag gtggcagtca ttttcttcga
    11281 taaaacgctg caatcctttc cgtagcccga ctgtagaaag cgtgatacgc ttcggactcc
    11341 atgcgtaacc gtaggtagcg gtcagtagtt ccaatgcctt caatacctca tccaggttat
    11401 cgagcggctc gcccattccc atcattacga cattagtcag tttatcccgt tccggcagcg
    11461 aatgaatctg gttcatgatc tggctggcgg tcaggttagc ggtatacccc tgtttgccgg
    11521 tcatacagaa cttacagttc atcttgcagc ccacttgtga cgacacgcac aacgttgccc
    11581 ggtcatcatc cggtatataa accgactcta caaaatggtt ctcacccact ttataaagat
    11641 acttcaccgt accatctaca gagcgcattt catctaccgg agcttccgct cccacctcat
    11701 agttctgctt gagcaactcc cggtgtttca atgacaaatt agtcatatca tcaatcgagg
    11761 ctaccttctt ttcgtaaagc caggatgcaa tctgtttggc agcaaagccg ggcataccca
    11821 gtctttttgt caatgattga agctctacaa gagtcattcc taaaagggga tatttagaca
    11881 ttcttctttc tgttgatagt ttatatctgc aaatgtaagg aaataaagtc gatttccgta
    11941 tagcaggaat gtaaaagtta acaaaaaagg gaagtatgcc tccgttatga ttcaaccacg
    12001 ctgatatatt gaagtagctt ttgcgccatt tcagaatcct cgccattctt tttcacttca
    12061 taaccgtacg cctcacggaa acaagccagc gcctcttccc gttcattaca aaagctgtgc
    12121 aaaaccccta agttctgaca agccagaatc gtatcttctt cctcccatcc caaatacttc
    12181 tttcgcagtt caagttctct gaagaaagcc tctttcgcca ttggataatt ctccaacttc
    12241 acataagcct gtgctttgta ataatatacc agacaggaag cattagggtc agcatcatcg
    12301 tgaatatcca aagacgtcgc aatacgaatc acgttatcat agtctttatt catgtaatac
    12361 tgctgcataa tatcacatct caatgcctca tatcggacag tcagttccgc cagacgcggt
    12421 ttttcgctga aatacatttc atgcagaaga gactcacgga agaataaagt agacgcctgc
    12481 tcatcgccac gttcattcat catccgtttg aattccctgc acagataata caactgttta
    12541 tgacaagcga cgatctgttt tttgctatct atctgtatag caatgtccaa cgcctgattc
    12601 atcagcatcc atgcttcatc gtatcgtttg atataataaa gacatttacc ctgcatacgc
    12661 aaacatttag ccactccacc ggacagtctg ccattcaatg actcgtgcat ttcagctact
    12721 ttccggaatt tctcggcagc actctcttcc tcatccttat agtaatcaca ataagccaga
    12781 tattcggaaa gttcaatgac ttctgcctga ctcttctcgt cagcagaagc cgcatgataa
    12841 tcaagcgccc tattcaaata gatcgccgct tcattgtatt gctcattgta gtaatatgcc
    12901 agagctagat ttcggcaggt attggcaatc tccagttccg gagtcggcac aatgttttcc
    12961 tgcatcacca atgctttcag gaaacagtcg catgccgttt cgtactcttc attacgggca
    13021 taccggcatc cctcattcat cttcaatacc gacttggcaa tgagtggcat ggcagcacct
    13081 tccatactct tctcactcac agcagctgcc gccttcgtca gatggaaaga actgctcaag
    13141 aaagtagcca tatcattagc aatgacagga attaaaaaag aatcgatctc atcaaagtcc
    13201 aattcggcat agacttcagg cgtaacttca ggattgtcgt tcatgatcgc cttccagcta
    13261 tcttccaaca gaaaacgatt cgtgcgatac agaatctcga aaatctccac atcacaaatc
    13321 caatccttca atatatccca ttcttgcatc ttatagcatt gataggtaat ctccacttta
    13381 tagcgatacg aatcatggta gcagaactgt ttcatgcgat agttataatc ggcaaaagtc
    13441 aacggatggg aaaggatttc ttcctcatcc agcagagcgg aaataatttc atggcgacta
    13501 tcatctatac attcgtcatc ttgagcgaaa tagcgttcga tcgcctctac catttgtgta
    13561 tcaccaatgc aatatcgtcc tcctttgttg gtgagccagc tgctcatttc cactctcaac
    13621 tgcgaccaaa gtatctgatt aatgtctgcc atgctcttca cttcatcttc ggtaaatcct
    13681 tctaaagtaa gtgaaagcat cagaagcgtt cttccaatct cttcggaacc ataatcagcc
    13741 gacaaacgcc gtagcacact gtcatagaat tgcccaacct cattgagccg gcaatatcca
    13801 cgcatatatt cattgagagc atcgtactga ccgaacgaaa ccagctcgtt gagcaataca
    13861 cttaaacagc gcggttgttc agccagcacc cacgaagcaa gaatatcttc ctgctgtgca
    13921 gacaaagcct tggagtaagt agacaaatat tgctttgaga acgacttggc atccgcctgt
    13981 gaaaagccat tcaactggaa atgagcgt
//
