Select genomic region:
Overview
1.1
1.2
3.1
12.1
23.1
37.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | Rnf_complex | E-MGC | 1 | 20,206 | Rnf complex C. sporogenes | RNF | 83%
Region 1.2 | Pyruvate2acetate-formate | SCFA | 40,847 | 63,838 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%

c00003_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_3)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 3.1 | Others_HGD_unassigned | Putative | 13,382 | 44,359 |

c00012_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_12)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 12.1 | acetate2butyrate | SCFA | 91,462 | 117,704 | Acetate to butyrate C. sporogenes | BUT | 100%

c00023_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_23)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 23.1 | Putrescine2spermidine | Aliphatic_amine | 247,941 | 272,183 | Arginine2putrescine R. gnavus | PUTR | 100%

c00037_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_45)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 37.1 | TPP_AA_metabolism | Putative | 161,744 | 190,660 | Threonine to propionate E. coli | PROP | 20%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | Rnf_complex | E-MGC | 1 | 20,206 | Rnf complex C. sporogenes | RNF | 83%
Region 1.2 | Pyruvate2acetate-formate | SCFA | 40,847 | 63,838 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 3.1 | Others_HGD_unassigned | Putative | 13,382 | 44,359 |
Region 12.1 | acetate2butyrate | SCFA | 91,462 | 117,704 | Acetate to butyrate C. sporogenes | BUT | 100%
Region 23.1 | Putrescine2spermidine | Aliphatic_amine | 247,941 | 272,183 | Arginine2putrescine R. gnavus | PUTR | 100%
Region 37.1 | TPP_AA_metabolism | Putative | 161,744 | 190,660 | Threonine to propionate E. coli | PROP | 20%

No primary metabolite regions were found in these records:
  c00002_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_2)
  c00004_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_5)
  c00006_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_11)
  c00013_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_22)
  c00024_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_36)
  c00038_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_56)
  c00039_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_58)
  c00040_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_59)
  c00041_gnlPro.. (original name was: gnl|Prokka|CCMEAMLH_60)

Compact view
c00001_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 20,206 nt. (total: 20,206 nt) Show pHMM detection rules used
Region on contig edge.
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00001_gnlPro.. - Region 2 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 40,847 - 63,838 nt. (total: 22,992 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00003_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 13,382 - 44,359 nt. (total: 30,978 nt) Show pHMM detection rules used
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00012_gnlPro.. - Region 1 - acetate2butyrate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 91,462 - 117,704 nt. (total: 26,243 nt) Show pHMM detection rules used
acetate2butyrate: (not (POR or POR_N or PFOR_II) and minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00023_gnlPro.. - Region 1 - Putrescine2spermidine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 247,941 - 272,183 nt. (total: 24,243 nt) Show pHMM detection rules used
Putrescine2spermidine: (minimum(2, [AdoMet_dc, Spermine_synt_N, Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00037_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 161,744 - 190,660 nt. (total: 28,917 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.