LOCUS       c00222_gnlPro..        11379 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JAJNCFGE_222.
ACCESSION   c00222_gnlPro..
VERSION     c00222_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:31:36
            Original ID  :: gnl|Prokka|JAJNCFGE_222
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11379
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11379
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[966:3437]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      967..3437
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..11379
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11379
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             52..927
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg222_1"
                     /sec_met_domain="Arginase (E-value: 8.3e-78, bitscore:
                     251.5, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPNVETFIGCDSSYRAASIVLYGAPYDSTTSYRPGARFGPAAIR
                     HESYGLETYSPYQNADLTDFDVFDSGDLELCFGSSELALADIEARAEEILKDGKFPLLL
                     GGEHLVTLGAVRAAVKKYPDLHIVHFDAHADLRDDYLGAKLSHACVLRRCHELVGDGHI
                     HQFCIRSGDRAEFEFAAQHTEMHKFDFTGLAELTAQLCESKVPVYLTIDLDCLDPSCFP
                     GTGTPEAGGVSFLQLLEAIRTVTKANIIGADLNELAPTLDTTGVSTATACKVLRETLIA
                     LDKGWPGFQV"
     CDS             967..2226
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg222_2"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 3.9e-45, bitscore:
                     144.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.4e-33,
                     bitscore: 105.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVLIIGCGGVASVAIHKCCQVPEVFTEICIASRTKAKCDKLAA
                     ELAPTTTTKITTAQVDADKVEEVIALIKAYQPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPENTDDPEWRAIYEKRCKEAGFSAYFDYSWQWAYAKKFEEAGLTALLGSGFDP
                     GVTQAYCAYAKKHEFDTIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPAMSIKREYNFDQVGDKDMYLLHHEEIESLAKNIPEAKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPVNFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGKKDGKDK
                     TYYIYNVCDHQECYKEVGSQAISYTTGVPAMCGALMLLTGKWTTKGVHTVEEFDPDPYL
                     DALDKYGLPRSESHNPALVD"
     CDS             2226..3437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg222_3"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 8.3e-15,
                     bitscore: 44.9, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRDSRPPFAGLANLSEEQLHRLPTPCYLLDEAQLRRNGEILLG
                     VQQRTGCRILLAQKAFSNFNVYPVLAPYLAGTEASGLYESRLGREELPEKENHVFCAAY
                     RTDEFEELLQYADHIVFNSPSQLAKFGPAAKAAGKSIGLRINPECSTQEGHEIYDPCAP
                     GSRLGTTRAQWDAAVAAHPELPALLDGLHFHTLCEQDADALAVTLAAVEKKFADLLPRM
                     KWLNFGGGHHITRPGYALDTLESCILSVRQKYGVQVYLEPGEAWALNAGYLVTTVLDTL
                     RNGDTSLAILDMSAACHTPDVIEMPYRPPLLDAGEAGEKAHTVRLGGPTCLAGDIIGDY
                     SFDAPLAEGDKLIFGDMAIYTTCKNNTFNGMPLPPIWLLGADGSCRELVHFGYQDFKMR
                     LGAQ"
     CDS             complement(3453..3611)
                     /locus_tag="ctg222_4"
                     /transl_table=11
                     /translation="MDCKRVTVIRIGPVISTRMKALHGNVWCFFVLSAVHLTSPFMKKA
                     FVAARKP"
     CDS             4098..4967
                     /locus_tag="ctg222_5"
                     /transl_table=11
                     /translation="MTLDYFYGQTGELFSFYRIPKALFQEQRFQSLSTDAKTLYGILLD
                     RMSLSVKNGWLDKQNRVFIIFTIEDVKRALCCADNKATKLLRELEKFGLIERKRRGQGK
                     PSLVYVKNFSAESSKESVKNRDNDDSCGFKIACQDPAKSRCNKTKENDTEMSETNLFYS
                     EESDGMSKRAQLEEYFSQSLEVDLLLRLCPDDEDTIYQIVDLLVDTCATNRKLLHIAGD
                     DRPAEVVRSRFMKLNADHIKFVLKCLAENSSPIRNMKQYLLASLYNAPTTIQLYYQNQT
                     NHDLAKRG"
     CDS             4964..5800
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg222_6"
                     /sec_met_domain="CbiA (E-value: 9.1e-28, bitscore: 86.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKISKKATTIAIVNQKGGTGKTTTCENLGVGLAAEGKKVLLVDA
                     DPQGSLTISMGWQKPDELPVTLSTLMQKAMNDQCIPPGEGVLHHAEGVDLIPASIELAG
                     LEVALVNTMSREKMLKQVLDSAKQDYDYILLDCTPSLGMLTINALAAADTALIPVQAQY
                     LSAKGLEQLLQTINKVHRQINPKLKIEGILLTMTDNRTNYGRQIDTLIRQAYGKHIKVF
                     GQTIPHSVRAAEISAAGKSIFVHDPKGKVAEAYKSLTKEVLADAEKQRKRQSEQLR"
     CDS             5757..6683
                     /locus_tag="ctg222_7"
                     /transl_table=11
                     /translation="MPKSSVNASLSSYDDIFSTEESRQEEQREQVQQIPIGELFPFKNH
                     PFKVLDDDSMSDTVESVKQYGVLSPLIARPRPKGGYEIISGHRRQHAAELAGLETLPVI
                     VRQMDDDAAIILMVDSNLQREHILPSERAFAYKMKLDAMKNQGTRSDLTSTQVVSKLRS
                     NEKLGAENNQSRETVRRFIRLTNLIPELLDMVDNKTVSFNPAVELSYLSPEQQQEVIRA
                     MDDTQNFPSVSQAKRIKKLAQDGTFTTETVIAIMGEEKKSELDTVTIKNDTLRKYFPRS
                     YTPKQMEDTIIKLLEQWQKKRQHSEER"
     CDS             6746..7171
                     /locus_tag="ctg222_8"
                     /transl_table=11
                     /translation="MKNDSNPIIRSEEVTIDMHICAALSESRSSGEIYFAAIAPDMELT
                     VITLDEAPDILPCFDEDDAYLNIPDSSLLLSYNPAQVLKLAGKHYLTGPVILVRTNMDG
                     EFISLTIDQVYLFQKYLMRHSVTLMADGQKLPCICID"
     CDS             7307..7753
                     /locus_tag="ctg222_9"
                     /transl_table=11
                     /translation="MEQNENTLSVLKIAPGQYPQQVEIDPDLKSLQQAVGGNIGASYPF
                     SDPVAIVYNDEGKLMGLPLNRALRDESGEAYDVVAGTFLVVGLGEEDFASLSPELAQKY
                     EEHFHQPEDFIRLGHRMMVVRVPDEAVCPEESKTTPPKDAGFDR"
     CDS             7784..8242
                     /locus_tag="ctg222_10"
                     /transl_table=11
                     /translation="MQEEIEHKTVNFAISTVKLSARTLLKGAQFFLRQYDKSASQGKQS
                     MNRLIRQNRGVTNLEIEKTGIKDFDRYAKRYHIDYAIQKDLSCTPPRYLIFFKAQDTDA
                     LNAAFKEYSASVLSKTERPSVLAKLHNLAQTIANLPDKVRHKEEERGL"
     CDS             8239..10020
                     /locus_tag="ctg222_11"
                     /transl_table=11
                     /translation="MNKKKFTKLLALYLPYLVIGLAATNLGEAWRLAEGKELGDKIVSL
                     MGTLPDTFANPLPSLHPLDILVGICCGAGLRLAVYLKSKNAKKYRHGMEYGSARWGTPA
                     DIAPFIAPKFEDNIILTKTERLMMSNRPPDPKNARNKNVLVVGGSGSGKTRYFIKPNLL
                     QCTSKSHPVSFVVTDPKGGLIQECGLALLKNGYKIRTMNTINFHKSMRYNPFAYIHEEK
                     DILKLVTTLMTNTKGEGQGGDPFWDKAERLLLTSLIAYLHYEAPAEEQNFATLLEMLNT
                     MQVSEEDEDYQNPVDLLFEDLAKKKPNSFAGRQYKLYKLAAGKTAKSILISCGARLSPF
                     DIQEIRDATMYDELELDKLGDRKTALFLIMSDTDSTFNFLISMIYSQLFNLLCDKADDV
                     YGGKLPVHVRCLIDECANIGQIPQLEKLVATIRSREISACLVLQTRSQLKAIYKDNADT
                     IVGNMDSQIFLGGSEPTTLKDLAEALGKETIDSYNNSDTRGNSPSYGTNYQKLGHELMS
                     RDELAVLDGGKCILQLRGVRPFLSDKYDLTQHPNYKMTSDADPKNALDIEKYLSHKEKI
                     RPDDQFVLVDVDSLPPA"
     CDS             10157..10372
                     /locus_tag="ctg222_12"
                     /transl_table=11
                     /translation="MEFFNSAVDVLKTLVVALGAGLGVWGAVNLMEGYGGDNPSAKSQG
                     MKQLMAGGGVALIGITLIPLLSGLFG"
     CDS             10520..10735
                     /locus_tag="ctg222_13"
                     /transl_table=11
                     /translation="MEFFNSAVDVLKTLVVALGAGLGVWGAVNLMEGYGGDNPSAKSQG
                     MKQLMAGGGVALIGITLIPLLSGLFG"
     CDS             10937..11377
                     /locus_tag="ctg222_14"
                     /transl_table=11
                     /translation="VETVLKAISDWIKSLLTAAIMSNLSGLFDDVNTQVGSIAQQVGTK
                     PSNFEPRVFAMIEALSRNVVLPIAGIILTFVACYELIQMITEHNNMANFEPVLLMKWIF
                     KTAISVWMISNTFDIIMAVFDVTQQVVANSSGIISGNTRVNDI"
ORIGIN
        1 ctacctgccg gcttttctgg aggagatgct gcgggaagtg gaggaacact gatgcacccc
       61 aacgttgaga cctttatcgg ctgcgacagc agctaccgcg ccgccagcat cgtgctgtac
      121 ggtgcgcctt acgattccac caccagctac cgccccggtg cacggttcgg cccggcggcc
      181 atccggcacg agagctatgg tctggagact tacagcccct accagaacgc cgacctgacc
      241 gattttgatg tgttcgacag cggcgatctg gagctgtgct tcggctctag cgagctggca
      301 ctggccgata tcgaggcccg ggcagaggag atcctgaagg acggcaagtt cccgctgctg
      361 ctgggcggtg agcatctggt cacactgggt gccgtgcggg ctgcggtgaa gaaatacccc
      421 gacctgcaca tcgtccactt cgacgcccac gccgacctgc gggacgacta tctgggcgcg
      481 aagctcagcc acgcttgtgt gctgcgccgc tgccacgagc tggtagggga tggccacatc
      541 catcagttct gcatccgcag cggcgaccgg gcagaatttg agtttgctgc ccagcacacc
      601 gagatgcaca agtttgattt taccggcctt gccgaactga ccgcacagct gtgcgagagc
      661 aaggtgccgg tgtacctgac catcgatctg gactgccttg acccctcctg cttcccgggt
      721 accggtaccc cggaagctgg cggcgtaagc tttttgcagc tgctggaggc tatccgcacc
      781 gtgaccaagg ctaacatcat cggcgcagac ctgaacgagc ttgcccccac gctggacacc
      841 accggcgttt ccaccgccac cgcctgcaag gtgctgcgcg agaccctgat cgcgctggac
      901 aagggctggc cgggctttca ggtataaata cgaacctacc attttacaga taaaggagta
      961 accgacatga gcaaagttct gatcatcggc tgcggcggcg tggcctctgt tgccatccat
     1021 aagtgctgcc aggtgcccga ggtgttcacc gagatctgca tcgccagccg taccaaggca
     1081 aagtgcgata agctggctgc tgagctggct cccaccacta ctaccaagat caccaccgca
     1141 caggtggacg cagacaaggt ggaggaggtc atcgccctca tcaaggctta ccagcccgac
     1201 ctcgtgatga acatcgccct gccttatcag gatctgacca tcatggatgc ctgccttgcc
     1261 tgcggcgtca actacatgga caccgccaac tacgagccgg agaacaccga tgacccggag
     1321 tggcgtgcca tctacgagaa gcgctgcaag gaagcaggct tctccgccta ctttgattac
     1381 agctggcagt gggcctacgc aaagaagttt gaggaagccg gcctgaccgc cctgctgggc
     1441 agcggcttcg acccgggtgt gacccaggct tactgtgcct atgccaaaaa gcacgagttc
     1501 gataccattg acaccatcga tattctggac tgcaacggcg gcgaccacgg ctatgccttt
     1561 gccaccaact ttaaccctga aatcaatctg cgcgaggtgt ctgcccccgg cagctactgg
     1621 gagaacggcc actgggtgga gatcccggct atgagcatca agcgggagta caacttcgat
     1681 caggtgggtg acaaggatat gtatctgctg caccacgagg agatcgagtc tctggcaaag
     1741 aacatcccgg aggcaaagcg catccgcttc ttcatgacct ttggccagag ctatctggac
     1801 cacatgcgct gtctggagga cgtgggcatg ctgtccacca cccccgtcaa cttcaacgga
     1861 caggagatcg tgcccatcca gttcctcaag gctctgctgc cggaccccgc cagccttggc
     1921 ccccgcacta agggcaagac caacatcggc tgcatcttta ccggcaaaaa ggacggtaag
     1981 gataagacct actacatcta caacgtctgt gaccatcagg agtgctacaa ggaagtgggc
     2041 agtcaggcca tcagttacac caccggcgtg ccggctatgt gcggcgccct gatgctgctc
     2101 accggcaagt ggaccaccaa gggcgtgcac actgtcgagg agtttgatcc cgatccgtat
     2161 ctggatgcac tggataagta cggcctgccc cgctccgaga gccataaccc ggctctggtg
     2221 gactgatgcg ggtgcgcgac agccgcccgc cctttgcggg gctggcaaac ctgtccgagg
     2281 agcagctgca ccgcctgccc accccctgct atctgctgga cgaagcccag ctgcgccgca
     2341 acggtgagat cctgctgggg gtgcagcagc gcaccggctg ccgcatcctg ctggcgcaga
     2401 aggctttttc caactttaac gtctacccgg tgctggcacc ctatctggca ggtaccgagg
     2461 ccagcggcct gtacgagagt cgcttgggca gggaagagct gccggagaag gagaaccatg
     2521 tgttctgcgc cgcctaccgg acagatgagt ttgaggaatt gctgcaatac gccgaccaca
     2581 tcgtgttcaa ctcgcccagc cagctggcaa agttcggccc ggcggcaaag gcggcgggca
     2641 aaagcatcgg tctgcgcatc aacccggagt gctccacgca ggagggtcat gaaatttacg
     2701 acccctgcgc acccggcagc cgtctgggca ccacccgtgc tcagtgggac gccgccgtgg
     2761 cggcgcaccc ggagctgccc gccctgctgg acggtctgca cttccatacc ctctgcgagc
     2821 aggacgcgga cgcgctggcg gtaacgctgg ccgcagtgga gaaaaagttt gcagacctgc
     2881 tgcccagaat gaaatggctc aacttcggcg gggggcacca tatcacccgc ccgggttatg
     2941 cccttgacac gctggaaagc tgcatcctct cggtgcggca gaagtacggc gtacaggtgt
     3001 atctggagcc cggcgaggct tgggcgctga acgcgggata tctcgtcacc accgtgctgg
     3061 acaccctgcg caacggggat accagtcttg ccattctgga tatgtccgca gcctgccaca
     3121 ccccggatgt catcgagatg ccctaccgcc cgccgctgct ggacgccggc gaggcaggag
     3181 agaaggcgca caccgtccgg ctgggcggcc ccacctgcct tgcgggggat atcatcgggg
     3241 attatagctt tgacgcccct cttgccgagg gcgataaact catcttcggc gatatggcca
     3301 tctacaccac ctgcaagaac aacaccttca acgggatgcc cctgccgcct atctggctgc
     3361 tgggcgcaga cggcagctgc cgggaactgg tgcacttcgg ttatcaggac ttcaaaatgc
     3421 gtctgggcgc acagtaaaat aaaaagcgtt tgtcacggct tgcgggctgc gacaaacgct
     3481 tttttcatga aaggggacgt aaggtgaacg gcagataaaa caaaaaagca ccacacgttt
     3541 ccgtgtagtg ctttcattct ggtggagatt accgggccga ttctgatcac ggtgaccctc
     3601 ttgcagtcca tgcacggcac tctcctgggt gagctaaacc ctcactcgtt tggcagcgac
     3661 aaaaaagcac tacacgtttt tgtgtagtgc tttcgttctg gtggagatta ccgggatcga
     3721 accggtgacc tcttgcatgc catgcaagcg ctctcccgaa cggtatcgaa acacaccccc
     3781 acacgaaagt gcggggacag gcttaatatc gcgttgatac gttctatcca cccaaaaggt
     3841 tcacagttgc atcctgcttc caggaatcat gctccgccta caaggcaatt ttaccaccca
     3901 attttcaagt gtgtcaatgg gttttgctca gagagaaggt catttacgag aaaagttttt
     3961 ttctgacagc ttacttagcg caattttgat tttacacatc aaagttgcgc tttttatttt
     4021 ccccaaaagt attgacaagg aggttttctc aacgatgccg atgtattatc gctgtttttt
     4081 atccatgaac caaccgcatg acccttgact acttctacgg acagactgga gagcttttct
     4141 ccttctaccg cattccaaag gctctttttc aggagcagcg gttccagagc ctgtccacgg
     4201 atgccaaaac cctgtatggt atcctgctgg accgcatgag cctgtcggtg aaaaacggct
     4261 ggctggacaa gcaaaaccgg gtgttcatca tcttcacaat cgaggatgtc aagagggcat
     4321 tgtgttgcgc agataacaaa gcaaccaagc tgctccggga acttgaaaag tttggtctga
     4381 ttgaacgaaa acgccgaggg caaggaaagc caagtttggt atatgtgaaa aacttttcgg
     4441 cagaatcttc aaaagagagt gtcaagaatc gtgataatga cgattcttgt ggcttcaaaa
     4501 tcgcgtgtca agaccctgca aaatcacggt gtaataagac taaagagaat gatactgaaa
     4561 tgagtgagac taatctcttc tattccgaag aatcggatgg gatgagtaag cgcgcccaac
     4621 tggaagaata tttttcgcag tctttggagg tagaccttct gctccggctc tgcccggatg
     4681 atgaggacac catctatcag atcgtagatt tgctggtgga cacctgtgct accaaccgca
     4741 agctgctgca catcgccggg gatgaccgcc ctgccgaggt agtgcgcagc cggtttatga
     4801 agctgaacgc cgaccacatc aaatttgtgt tgaagtgcct tgcagagaac agcagcccaa
     4861 tcaggaacat gaagcaatac ctgctcgctt ctctgtacaa cgcaccgacc accatacagc
     4921 tttactatca gaatcagacc aaccacgatt tagcgaaacg ggggtgataa aaatttccaa
     4981 aaaagcaact acgattgcca ttgtcaacca aaagggaggc actggcaaaa caacaacctg
     5041 tgaaaacttg ggtgtcggtc ttgccgccga gggtaagaag gtcctacttg tagacgctga
     5101 cccgcagggt tcactcacca ttagtatggg ctggcagaag ccggacgaac tgcccgttac
     5161 tctttctacc ctgatgcaga aagccatgaa cgaccagtgc attccgcccg gtgaaggtgt
     5221 gctgcaccat gcagagggtg tagacctcat cccggccagc attgagctgg cagggctgga
     5281 agttgccctt gtcaatacca tgagccggga aaaaatgctg aagcaagtct tggacagtgc
     5341 aaagcaggac tatgactata ttttgttgga ctgcactccc tcccttggga tgctgaccat
     5401 taacgcgctg gcggcggcag acactgctct gatacccgta caggcacagt acctttccgc
     5461 gaaaggtctg gaacagcttt tgcagaccat caacaaggtg catcggcaga tcaacccaaa
     5521 gctgaaaatc gaaggtatcc tgctgacgat gacagataac cgcaccaact atggccgaca
     5581 aatcgacacg ctgatccggc aggcatacgg aaagcacatc aaagtgttcg gtcagacgat
     5641 tccccactcc gtccgtgcag cggaaatcag cgcggcgggt aagagcatct ttgtccatga
     5701 cccgaaaggc aaagtggcag aagcctataa atctctgacg aaggaggtgc tggccgatgc
     5761 cgaaaagcag cgtaaacgcc agtctgagca gctacgatga tattttttcc accgaagaat
     5821 cccggcagga agaacagcgc gagcaggtgc agcagattcc gattggagag ctgtttccat
     5881 tcaagaacca tcccttcaag gttctggacg atgattctat gagcgatacc gtggaaagtg
     5941 tcaagcagta cggtgtgctt tcgccgttga ttgcccgccc cagaccgaag ggcggctatg
     6001 aaattatctc cgggcaccgc cgtcaacacg ctgcggagct ggccggactg gaaaccctgc
     6061 cggtcattgt gcgccagatg gacgatgatg ctgccataat cctcatggta gatagcaatt
     6121 tgcagcgtga gcatattctg cccagcgaga gagcgtttgc gtacaaaatg aagttggatg
     6181 ccatgaaaaa tcaaggtaca aggtcagatt taacttcgac acaagttgtg tcgaagttgc
     6241 ggagcaatga aaagctgggc gcagagaata atcaaagtcg tgagactgtt cgacgtttca
     6301 tccgtctgac caacctcatt cccgaactgt tggacatggt agataacaaa acggtgtcct
     6361 tcaaccctgc cgtggagctt tcctatcttt ctcctgaaca acagcaggaa gtgatccggg
     6421 caatggatga tacccagaac tttccttctg tctcacaagc aaagcgtatc aagaagctgg
     6481 ctcaggatgg aacttttaca acggagacgg tcattgccat tatgggcgag gagaaaaaga
     6541 gcgagcttga tacggtgacc atcaaaaatg acaccctgag aaaatacttt ccccgcagct
     6601 atacgcccaa acagatggaa gataccatca tcaagctgct ggagcagtgg cagaaaaagc
     6661 gtcagcacag tgaagaacgc tgacaggata tgaattggaa agacccggtt gggtcttttt
     6721 ctttagaaaa aaggagaaaa tgcctatgaa aaatgattct aatcccatta ttcgttccga
     6781 ggaagtcacc attgatatgc acatctgtgc ggcactgtcg gaaagcagga gcagtggcga
     6841 gatctatttt gctgccatcg ccccggatat ggaactgaca gtcatcacgc tggacgaggc
     6901 tcccgacatt ctgccctgct ttgacgagga tgatgcgtac ctgaacatcc ccgacagctc
     6961 gctgctgctc agctacaacc cggcgcaggt gctgaaactg gcgggcaagc actatctgac
     7021 cggtccggtc attctggtgc gcaccaatat ggatggcgag ttcatctcgc tgacgatcga
     7081 tcaggtctac ctctttcaga agtatctgat gcgccatagc gtcaccctga tggctgacgg
     7141 ccagaagctg ccctgcatct gtatcgactg aggtgtgcca tgctgaactt ttttatcggt
     7201 ttcgcatttt ttgaagccgg cgcttttttc ggcttctttg tggcagctct gttgaacgcc
     7261 gcccatgccg ggcaggagat ctctatcaaa ttcgaggagg acgataatgg aacagaacga
     7321 gaacaccttg tcggtgctga aaattgcacc ggggcagtat ccgcagcagg tcgagatcga
     7381 ccctgacctg aaatctttgc agcaggcagt cggcggcaac atcggtgcca gctatccgtt
     7441 cagtgacccg gtagccatcg tctacaacga tgagggtaag ctgatgggtc tgccgctgaa
     7501 ccgtgccttg cgggatgaaa gcggcgaagc ctatgatgtg gtcgccggaa cctttctggt
     7561 ggtcggtctg ggtgaggaag attttgcatc actttccccg gagctggcac agaagtacga
     7621 ggagcatttt catcagccgg aagattttat ccggctgggg catcggatga tggttgttcg
     7681 tgtgcccgat gaagcagtct gcccggaaga aagcaaaacc accccgccga aggatgccgg
     7741 atttgaccgc taaacacgac tttctgcact ggaggtgatg gaaatgcagg aagaaatcga
     7801 gcacaaaaca gtcaattttg ccatttcgac tgtaaaactg tctgcccgca ctctgctgaa
     7861 aggggcgcag ttctttctgc gccagtacga caagagtgca tcgcagggca agcagtccat
     7921 gaatcggctc atacggcaga accggggtgt gaccaatctg gaaatcgaaa agactggcat
     7981 caaggatttt gaccgctacg ctaagcggta tcacatcgac tacgccatcc agaaagacct
     8041 gtcctgcacg ccgccccggt acctgatttt cttcaaggcg caggacactg atgcgctcaa
     8101 tgctgcattt aaggagtatt cggcatcggt gctgagcaag accgagcgtc cctctgtgct
     8161 ggccaagctg cacaatctgg cacagaccat tgccaacctc cccgataaag tacggcacaa
     8221 agaggaggaa cgtggcttat gaacaagaaa aagttcacca agctgctggc cctgtacctg
     8281 ccttatctgg tgattgggct ggctgcgacc aatcttggcg aggcatggcg gctggccgag
     8341 ggtaaggagc tgggcgacaa aatcgtgtcc ctgatgggta cgctcccaga tacatttgcg
     8401 aacccgcttc ctagtctgca tccactggat attctggtgg gcatctgctg cggtgctgga
     8461 ctgaggctgg ccgtctatct gaaaagcaaa aacgccaaaa agtaccggca cggcatggag
     8521 tatggctccg cccgatgggg cacaccggcg gatattgcac catttatagc tccgaaattt
     8581 gaggacaaca tcatactgac caaaacggaa cgcctaatga tgagcaaccg tccacctgac
     8641 cccaaaaatg cacgaaacaa aaacgtgctg gtggtcggcg gctctggcag cggtaaaaca
     8701 aggtacttta tcaagccgaa cttgcttcaa tgtacgtcta aaagccatcc agtttcattc
     8761 gtggtgactg acccaaaagg cggtctcatt caagaatgcg gccttgcctt gctgaagaac
     8821 ggatataaaa tcaggacgat gaacaccata aattttcaca agtccatgcg ctacaatccg
     8881 ttcgcatata tccacgagga aaaggatatt ttgaagctgg tcacgaccct tatgaccaac
     8941 accaaaggtg aaggtcaggg cggcgatccg ttctgggaca aggcggaacg gcttttgctg
     9001 acctcgctga ttgcctatct gcactacgaa gccccggctg aggaacagaa ttttgctacg
     9061 ctgctggaaa tgctcaacac catgcaggtg tccgaggagg acgaggatta tcagaatccg
     9121 gttgatttgc tctttgaaga tttggcaaaa aagaagccaa acagctttgc agggcggcag
     9181 tacaagctct ataaattggc tgccggcaag accgcaaaat ccatcctgat ttcctgcggt
     9241 gcccgcctct cgccctttga catccaagaa atccgggatg cgaccatgta cgatgagctg
     9301 gagctggata agctgggcga ccgaaaaaca gccttgttcc ttatcatgtc ggatacggac
     9361 agcacgttca atttccttat cagcatgatc tactcccagc ttttcaattt gctctgtgac
     9421 aaggcagatg atgtgtacgg cggaaagctg cctgtccatg tgcgctgcct gatcgacgag
     9481 tgtgccaaca ttggccagat tccgcagctg gaaaaactgg tggcaaccat ccgcagccgt
     9541 gagatctcgg cgtgtctggt tttgcagacc cgcagccagt tgaaagccat ctacaaggat
     9601 aatgcggata ccatcgtggg caacatggac agccagattt tcctcggcgg cagtgagcct
     9661 accaccctga aagatcttgc cgaagcactc ggcaaggaaa ccatcgacag ctacaacaat
     9721 tctgacaccc gtggcaatag cccaagctat ggaaccaact atcaaaaact cggccacgaa
     9781 cttatgagcc gggatgagct tgcagtgctg gacggcggca agtgcatttt gcagttgcgt
     9841 ggtgtcagac cgtttctttc agacaaatac gatctgaccc agcatccgaa ctataaaatg
     9901 acatcggatg ctgaccccaa aaatgctctg gatattgaaa aatatctgag ccataaagaa
     9961 aaaatccgcc cggacgatca gttcgtcctc gtggatgttg attcactccc gcccgcctga
    10021 caaagacgag cggttatttt ttatcctgac ccaaaaggcg caccagcaaa tcagcccttg
    10081 ccgcagttta cggcagttca caagtgggtt tcgggtgtgc gcaggggcac tttttgccaa
    10141 acaaaggaga cgaaatatgg aatttttcaa tagtgcagtg gacgttctga agactctggt
    10201 ggtcgctctg ggtgccggtc tgggtgtgtg gggggccgtc aacctcatgg aaggttatgg
    10261 cggcgataac ccctctgcga agtcgcaggg catgaagcag ctgatggccg gcggtggtgt
    10321 cgccctcatc ggtatcaccc tgattcctct gctgagcggt ctgttcggct gatacaagcc
    10381 ctcatctgat tcaataaaca acacattttg acccaaaggt ataccagaaa atcagctctc
    10441 gccgcagctt gcgggcagta acaaatggat tttaggcgta tacaggatca ttttttcaag
    10501 gcaaaggaga gatacaacga tggaattttt caatagcgca gtggacgttc tgaaaacttt
    10561 ggtcgtggca ctgggtgccg gtctgggcgt gtggggtgct gtgaacctca tggaaggtta
    10621 cggcggtgat aacccctccg caaagagtca gggtatgaag cagctcatgg ctggcggtgg
    10681 tgtcgccctg atcggcatta ccctgatccc cctgctgagc ggtctgttcg gctaaaaact
    10741 gcgggcggca tctgccgccc atacatattg ctccaactca ccgtggctaa cggtttttgt
    10801 acttgtggag cgaattttca agccatacgt tctatcaaaa aggagatgtt tctatgaatt
    10861 ttttgacgaa cctcatcttt gttctcaacc tgctcaagac cctcatcaac catttctttt
    10921 aaggtggtgg ctctgagtgg aaactgttct caaagcgatt tcagattgga tcaagtcgct
    10981 gctgactgcg gccatcatgt ccaatctgtc cggcctgttt gatgatgtca atacacaggt
    11041 gggcagcatc gcacagcagg tcggcacaaa gccatccaat tttgagccgc gcgttttcgc
    11101 catgatcgag gctctgtccc gcaatgtggt gctgccgatt gctggcatca ttttgacctt
    11161 cgttgcctgt tatgaactga ttcagatgat cacagaacat aacaacatgg caaattttga
    11221 gcctgtcctg ctgatgaaat ggatcttcaa gactgccatt tcggtctgga tgatctccaa
    11281 caccttcgac atcatcatgg cggtgttcga tgtgacgcag caggtggtgg caaattccag
    11341 cggcattatt tccggcaaca cacgggtcaa cgatatcgg
//
