LOCUS       gnlProkkaHKHAAPHC_184   2439 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HKHAAPHC_184.
ACCESSION   gnlProkkaHKHAAPHC_184
VERSION     gnlProkkaHKHAAPHC_184
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 05:37:20
            Original ID  :: gnl|Prokka|HKHAAPHC_184
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2439
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..804
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg184_1"
                     /sec_met_domain="APE_KS2 (E-value: 6.6e-18, bitscore: 52.9,
                     seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLGASGIIESIVCMHELKQGILFGTPGYETPGVPMPIPVYATHR
                     SIPMKHCVKTASGFGGCNAAIVLSLPEYTPFKDEDNTLPEIRCTREVRIENSSVFINNE
                     LIFHSEEPDFGTFIRDTYKKTGGNNLKFYKMDDLCKLGYVAAEYLLEGKTFAPLEMGML
                     LANAASSLHTDIRHQQLIDREGDQAASPAVFVYTLPNVVSGEICIRHKIQGENTFFITE
                     AYQPEKLERYARIVMQKGKLNYCIIGWCELWKNTYKAVFKLIEKQ"
     protocluster    1..2439
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[0:2254]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..2254
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..2439
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2439
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             810..1097
                     /NRPS_PKS="Domain: PP-binding (16-79). E-value: 1.5e-10.
                     Score: 33.4. Matches aSDomain:
                     nrpspksdomains_ctg184_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg184_2"
                     /sec_met_domain="PP-binding (E-value: 1e-11, bitscore:
                     33.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELIDKLKVELIEALNLEEITPEDIDSEAPLFGDDGLGLDSIDA
                     LEIILILERNYGIKIENPAKGKEIFYSVRTLADYITAHQKRGRSMSPVWE"
     aSDomain        858..1046
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg184_2_PP-binding.1"
                     /evalue="1.50E-10"
                     /label="ctg184_2_PP-binding.1"
                     /locus_tag="ctg184_2"
                     /protein_end="79"
                     /protein_start="16"
                     /score="33.4"
                     /tool="antismash"
                     /translation="NLEEITPEDIDSEAPLFGDDGLGLDSIDALEIILILERNYGIKIE
                     NPAKGKEIFYSVRTLADY"
     CDS             1160..2254
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (98-360). E-value:
                     1.1e-36. Score: 118.5. Matches aSDomain:
                     nrpspksdomains_ctg184_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 239; E-value:
                     1.6e-72)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg184_3"
                     /sec_met_domain="APE_KS2 (E-value: 1.9e-133, bitscore:
                     433.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKITLFPTALDVPVSEVKQSNEELKKLLSLPSGKTYSRTALLGL
                     WAAQGAARDAELDFTSPRIGLISSTSIGGMDASERFYASFREDNRKGRLRDIISHDCGS
                     STEMIAAYLGVKGTVTTLSTACSSAANAIMLGARLIRHGLLDAVLVGGTDALCRFTLNG
                     FNSLMILDKEHCRPFDRTRAGLNLGEGAGYLVLQSDKSLTKAPYCELSGYANANEAYHQ
                     TGSSPDGDGPFLSMSQAIASAGLTAGAIDYINVHGTGTPSNDASEGKAIRRIFDTRIPP
                     FSSVKAFIGHTLGASEGIEAVYSVLSIRHGLIYPNLNFHLSDEESGLIPETVFRSGLPI
                     RHVLSNSFGFGGNNSSLVFSTLTQ"
     aSDomain        1454..2239
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg184_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.10E-36"
                     /label="ctg184_3_PKS_KS.1"
                     /locus_tag="ctg184_3"
                     /protein_end="360"
                     /protein_start="98"
                     /score="118.5"
                     /tool="antismash"
                     /translation="SHDCGSSTEMIAAYLGVKGTVTTLSTACSSAANAIMLGARLIRHG
                     LLDAVLVGGTDALCRFTLNGFNSLMILDKEHCRPFDRTRAGLNLGEGAGYLVLQSDKSL
                     TKAPYCELSGYANANEAYHQTGSSPDGDGPFLSMSQAIASAGLTAGAIDYINVHGTGTP
                     SNDASEGKAIRRIFDTRIPPFSSVKAFIGHTLGASEGIEAVYSVLSIRHGLIYPNLNFH
                     LSDEESGLIPETVFRSGLPIRHVLSNSFGFGGNNSSLVFS"
     CDS             2258..2437
                     /locus_tag="ctg184_4"
                     /transl_table=11
                     /translation="MCPVYINRIASIHAESRNEKPYFSAQEPDYKEMITNANLRRRMSR
                     MIKMGVACGLECLKD"
ORIGIN
        1 cataccttgg gagcatcggg aatcattgaa agcattgtct gtatgcacga actgaaacaa
       61 ggcatcctgt tcggcactcc gggttacgaa acgccgggag ttcctatgcc gataccggtc
      121 tatgccaccc accggagcat cccgatgaaa cattgcgtaa aaaccgcttc gggattcggc
      181 ggatgcaacg cagccattgt cttatcttta ccggaatata ctccgttcaa agatgaggac
      241 aacaccttgc ccgaaatccg atgtacacgg gaggttcgta ttgaaaacag ttctgtcttc
      301 ataaacaacg aacttatttt tcattccgaa gaaccggatt tcggcacatt tatacgtgat
      361 acctataaaa aaacaggcgg aaacaacctg aaattctata aaatggatga cctttgcaaa
      421 ttgggatatg tggccgccga atacttgctg gaaggtaaga cattcgctcc actggaaatg
      481 gggatgttac ttgccaatgc cgcttcctct ctgcatacgg acatcagaca ccagcaactg
      541 atagaccggg aaggagacca ggcagccagt ccggctgtat ttgtttacac actacccaat
      601 gtagtgtccg gcgagatttg catccgccac aagatacaag gggaaaacac ctttttcatc
      661 actgaagcct atcagccgga aaaactggaa agatacgcac gtatagtcat gcaaaaaggg
      721 aaactgaact attgtatcat cgggtggtgt gaattatgga agaacaccta taaagcagta
      781 tttaaactga ttgaaaaaca ataaagaata tggaagaatt gattgataaa ctgaaagttg
      841 aattaataga agcattgaat ctggaagaaa tcactccgga ggacattgac agtgaagcac
      901 ctttattcgg agatgacggt ctgggccttg actcgattga cgcattagag attatcctga
      961 ttctggaaag gaattatgga atcaagatag agaatcctgc caaaggcaag gaaatattct
     1021 attcggtacg taccctggca gactacatca ccgcccatca gaaacgagga agatctatgt
     1081 caccggtctg ggagtgattt cgggcatagg gaaaggagtg gaagaaaacc tggattcctt
     1141 aaaagccggg aaacacggta tggggaaaat cacccttttc cccaccgcac ttgacgtacc
     1201 cgtgtccgaa gtaaaacaga gcaatgaaga attaaagaaa ctcctgtccc ttccatccgg
     1261 caagacgtat tcacgtacag ccttgctggg cttgtgggca gcccaaggag cggcccgtga
     1321 tgcggaactc gatttcactt ctccccgtat cgggctcatt tcttccactt ccatcggagg
     1381 aatggatgca agcgagcggt tttatgcctc tttccgggaa gataaccgaa aagggagatt
     1441 acgtgacatt atctcccatg actgtgggtc cagtaccgaa atgatagccg cttatttggg
     1501 agtgaaagga acggtgacca ccctcagcac cgcctgttct tccgccgcaa atgccattat
     1561 gttaggggca cgcctcatcc ggcatggtct gctggacgct gtccttgtag gcggaacgga
     1621 tgccttatgc cgtttcacgc tcaacggttt caattcattg atgatactgg acaaagagca
     1681 ctgccgtcct ttcgaccgca cacgtgccgg actaaacctg ggagaaggag ccggatacct
     1741 tgttcttcaa tctgataaat cccttactaa agctccttat tgcgaactca gcggttacgc
     1801 caatgccaat gaagcctacc accagacagg aagttccccc gacggagacg ggcctttcct
     1861 ttccatgagt caggccatag cctctgccgg gctgacagcc ggagccatag actatatcaa
     1921 tgtacatggt acaggcactc ccagcaacga cgcttccgaa gggaaagcca tccggcgtat
     1981 cttcgatacc cgtattcctc ctttcagttc ggtcaaggct ttcatcgggc acaccctggg
     2041 agcctcggaa ggaatagaag ccgtatattc cgtactctcc atccgtcacg gactgattta
     2101 ccctaatctg aacttccatc tgtccgatga agaaagcggc ctcattcctg aaacggtttt
     2161 ccggtcggga cttcccatac ggcatgtatt atccaactcc ttcggattcg gcggcaacaa
     2221 ctcatctctc gtattttcca ctctaaccca atagcgtatg tgcccagtat atatcaaccg
     2281 tatcgcctct atccatgcgg aaagcagaaa tgaaaagcct tatttctccg cacaggaacc
     2341 tgattataaa gaaatgatca ccaacgccaa tctgcggagg cgcatgagcc gcatgatcaa
     2401 gatgggagta gcctgcggac tggaatgtct gaaagatat
//
