LOCUS       c00061_gnlPro..         5131 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOHANEMP_61.
ACCESSION   c00061_gnlPro..
VERSION     c00061_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 10:06:49
            Original ID  :: gnl|Prokka|AOHANEMP_61
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5131
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5131
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[848:5129]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      849..5129
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5131
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5131
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             131..802
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="MESTISAAPQISIDREKTLRSHRRYWVLRRAQDIVFSLLALILLA
                     PLALLISLAIVLDSPGDGAIFRQRRVGRDGKLFWLYKFRTMCPDAEEQLNELLSQNQMD
                     GPVFKIKGDPRITRVGRFLRKTSLDELPQLLNVLQGDMSIVGPRPALPREVELYSDYQR
                     QRLYVTPGLSCYWQIAPHRNEMSFDEWVALDMKYIQERSFWVDWKIIFLTVRAMLMKYG
                     E"
     CDS             complement(849..2507)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="ILVD_EDD (E-value: 1.1e-224, bitscore:
                     735.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELERPLIGVVSAYSEIVP
                     GHMNLDKIAEAVKAGVQMAGGTPILIPAIGVCDGIAMGHVGMKYSLASRELICDSVETM
                     LMAHQLDGLVLVPNCDKIVPGMVMAAVRMDVPAVVCSGGPMLAGTYGGEEVSLSKMFEA
                     VGAYKAGMITDEQLEDCTCNCCPSCGSCSGMYTANSMNCLCEAIGIALPGNGTIPAVYS
                     KRLQLAKHAGMAVMEMVRKGITARQIINERSIRNALTCDMALGCSTNTVLHLLAIAYEA
                     GVPIDLKLFNEISAKTPNLCHLAPAGPTHMPDLYAAGGIPAVQAELAKKGLLDLDVPTV
                     TGKTLGENIKGAHILNEKAIRPIENPYSETGGLQILWGNIAPDGCVVKRSAVAPEMQQH
                     SGPARVFNSEEEAIAAIYAGKIVPGDVVVIRYEGPKGGPGMREMLNPTSALAGMKLDKT
                     VALITDGRFSGASRGAAIGHVSPEAASGGPIGLIEEGDTISIDIPNASITLEVSDAVLA
                     ERKAKYVAPEPNIKTGWLSRYARMVTSANLGAVLK"
     CDS             complement(2673..3692)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="IlvN (E-value: 2.5e-75, bitscore: 240.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.7e-66, bitscore: 210.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAKRRMEAELPIEKVGAELRSMMSWLKK"
     CDS             complement(3792..4355)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_4"
                     /sec_met_domain="ALS_ss_C (E-value: 6.4e-29, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKALERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             complement(4371..5129)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-52, bitscore:
                     165.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SELGKNVDVDLAIAGDVFYVLSGMLPLIEEKKHPDWMKMIHEWQA
                     QDYHPVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSRGFITSGG
                     LGTMGFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIITVIFNNSV
                     LGMVRQWQTNFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFADALQQKG
                     PTWIECIIDKDEKVLPMIPGGGDINDIIME"
ORIGIN
        1 ttttttcact ttttttcagc aggcttactg tcccccgccc gccgcgcttc atccggttga
       61 attgcgtcct gttttatgtt aaaataatgt aaagattcta cacattttac aggcaggagt
      121 gggtcattgc atggagtcaa caatcagcgc cgccccgcaa atttctatcg accgggaaaa
      181 gacgctgcgc agccaccggc gttactgggt gctgcggcgt gcacaggaca tcgtattctc
      241 cctgctggcg ctgatcctgc ttgcgccgct ggcactgctg atcagccttg ccatcgtgct
      301 ggacagcccc ggagacggag ctattttccg gcagcggcgg gtaggacggg acggcaagct
      361 gttctggctg tataagtttc gtaccatgtg cccggacgcc gaggagcagc tgaatgagct
      421 gctgagccag aaccagatgg acggcccggt gttcaagatc aagggcgacc cccgcattac
      481 ccgggtggga cgttttctgc gcaagaccag tctggacgag ctgccacagc tgctcaacgt
      541 gctgcagggc gatatgagca tcgtggggcc gcgccccgca ctgccccggg aggtagagct
      601 gtacagcgac taccagcgcc agcggctgta cgtcaccccc ggactgagct gctactggca
      661 aatcgcaccc caccgtaacg agatgagctt tgacgagtgg gtggcgctgg atatgaaata
      721 catccaggag cgcagcttct gggtggactg gaagatcatc ttcctcaccg tccgcgccat
      781 gctcatgaaa tacggagagt gacaaaagcg cctgttgtgc atccgcacaa caggcgcttt
      841 cgttacgttt atttcagcac tgcacccaga tttgcactgg tgaccatgcg ggcgtaacgg
      901 ctcagccagc cggtcttgat gttgggctcg ggcgcaacgt actttgcctt gcgctcggcc
      961 agcactgcat cgctgacctc cagcgtgatg gaggcgttgg ggatatcaat ggaaatggta
     1021 tccccttctt cgatcaggcc gatggggccg ccggaggccg cctccgggct gacatggccg
     1081 atggcagcac cgcgggatgc gccggagaag cggccgtcgg tgatgagggc caccgtctta
     1141 tccagcttca tgcctgccag cgcagaggtg gggttgagca tctcccgcat gcccgggccg
     1201 cccttggggc cttcgtagcg gatgaccacc acatcgcccg ggacgatctt gcccgcgtag
     1261 atggcggcaa tggcctcctc ctcgctgttg aacacccgcg ccgggccgga atgctgctgc
     1321 atctccgggg cgacagcgct gcgcttgaca acgcagccgt ccggggcaat gttgccccac
     1381 aggatctgca gaccgccggt ctcagagtag gggttctcga tgggacggat ggccttttcg
     1441 ttcaggatat gggcaccctt gatattctcg ccaagggtct tgccggtgac ggtgggcaca
     1501 tccagatcca gcaggccctt cttggccagc tccgcctgta ctgccgggat gccgcccgct
     1561 gcgtacagat ccggcatatg ggtgggacct gccggtgcca gatggcacag gttgggggtc
     1621 ttggcgctga tctcgttgaa cagcttcagg tcgataggca caccggcctc gtaggcgata
     1681 gccagcaggt gcagcaccgt gttggtggag cagcccagcg ccatatcaca ggtcagtgcg
     1741 ttgcggatgg agcgctcgtt gatgatctgg cgcgcggtga tgcccttgcg caccatctcc
     1801 attacggcca taccggcgtg ctttgccagc tgcagacgct tggagtacac agccgggatg
     1861 gtgccgttgc cgggcagggc aatgccgatg gcctcgcaca ggcagttcat gctgttggcg
     1921 gtgtacatac cggagcagct gccgcagctg ggacagcagt tgcaggtgca gtcctccagc
     1981 tgctcgtcgg tgatcatacc ggccttatag gcacccacgg cctcgaacat cttggaaagg
     2041 ctcacttcct cgccgccgta agtaccggcc agcatggggc cgccggagca gaccacggcg
     2101 ggcacatcca tgcgcaccgc tgccatcacc atgccgggca cgatcttatc gcagttgggc
     2161 accagcacaa ggccgtccag ctggtgtgcc atcagcatgg tctccacgct gtcgcagatc
     2221 agttcacggg aggccaaaga gtacttcatg cccacatgac ccatagcgat gccatcgcat
     2281 acaccgatgg cggggatcag gatgggggta ccaccggcca tctgcacacc ggccttgaca
     2341 gcctcggcga tcttatccag attcatgtgt ccgggcacga tctcgctgta ggcgcttacc
     2401 acgccgatga gggggcgctc cagttcctcc ggggtgtagc ccagcgcata aaacaggctg
     2461 cggttgggcg cgcgctccga gcccttggtc acgttgtcac ttctcattgc aaatcctctt
     2521 ttctgataaa gccctctccg tcacggttgc gccgtgccac ctctcccgag agggagaggt
     2581 ttcgcggagg agctataagg ttcccttttc aactaaaact ccccctttcg ggggagctga
     2641 ccgccgaaaa gcggtctgag agggttctcc tcttacttct tcagccagct catcatgctg
     2701 cgcagctcag cacccacctt ctcgatgggc agctcagcct ccatgcggcg cttggcaagg
     2761 aagtgcacct tgcggccgcc cttggggctc atctcggtca ggaactcaga agcaaaggtg
     2821 ccgtcctgga tctcggtcag aaccttcttc atctccttgc gggtctcctc ggtaatcagg
     2881 cgcttgccgg tgcggtagtc gccgtactcg gcagtgttgg agatggagta gcgcatcttg
     2941 gagaagccgc cctcgttgat caggtcaacg atcagcttca tctcgtggca ggtctcaaag
     3001 taggccatct cgggctcgta gccggcctcc accagcgtat cgaagccggc gtggatcagc
     3061 tcggaaacac cgccgcacag cacggcctgc tcgccgaaca gatcggtctc ggtctcctcc
     3121 ttgaaggtgg tctgcagaat gcctgcacgg cctgcgccga tgccggaagc ataagccagt
     3181 gcgatatcct tggccttacc ggtgtagtcc tgctccacgc agatcagaga ggggcagccc
     3241 tcgccctcgg tgtacaggcg gcgcacgatg tggccggggc ccttgggagc gatcatgatg
     3301 acgtccacgt tcttgggcgc ggtgatggtc ttgaagtgga tgttgaagcc gtgtgcaaag
     3361 gccagtgcct tgccctcggt catgtaggga gcaacctggg tgttgtagat atcggcgcac
     3421 agctcgtcgg gcaccagcat catgacaaca tcgccggcct tggcagcctc ttccacctcc
     3481 atgaccttga agttgtcatg ggtggcagcg aactcagaag cctttgccca gtgggcagag
     3541 cccttgcgca ggccgaccac aacgttgacg ccgctctcgg ccagattctc agagtgtgca
     3601 tgaccctggc tgccgaagcc gataacagcg acggtcttgc cgtccagcac gccgaggttg
     3661 cagtcggaat cgtagtattt cttgatagcc ataatcgtta gtctcctttt acattaactg
     3721 gttgttttat cttccggtct tgtatgctct gttctatctt tcgctcaccc tgagcggaaa
     3781 agcaatgtga tttatgcccg tcttgcgccc ggcggaggca gctggacgga gcgcacctcc
     3841 tgcggcggtt tctggatatg ctggtgcatc ccgccgcgct ccagtgcggt aacgccggtg
     3901 cggcactgct caaggatgtt gtagccctcg aacattttca ggaaagcgtc cagcttgtcc
     3961 ggccggccga tgagttcaaa gaccatgctg tccggggaaa gatcgatgat ctttgccttg
     4021 tagatgcagg cgatctcccg cagctctgtg cggttgtgca cgtccgattc caccttgagc
     4081 agcagcagct cccgctccag cgctttttcg ctgtccagca cgaacacctg ccgggtgact
     4141 tccagccgct cggtctgcaa taccagctgc tgcaaggcct tttcatcgct ggtaatggtc
     4201 actgtgatgc ggctgactgc cgggtcgttg gtggcggaca ccgtaaggct gtcgatattg
     4261 aagccgcggc ggcagaacag gctggacacc cgggccagaa cgccgctctg gttgtccacc
     4321 agcaggctga tgaccctgcg ctgatcagat tccatgatgc tgtgtcctcc ttattccatg
     4381 atgatgtcgt tgatatcgcc gccgccgggg atcatgggca gcaccttttc gtccttgtca
     4441 atgatgcact cgatccaggt ggggcctttc tgctgcaggg catctgcaaa ggcttcctga
     4501 aactccggca ggttggtgca gcggtagccc ttcaggccaa agccgtctgc cagcttgaca
     4561 aaatcggtct tgcggtgggg gtcggtctgg ctgtaacgct tgccgtaaaa gttggtctgc
     4621 cactggcgca ccatgcccag caccgagtta ttgaagatga ccgtgatgat gggcagctcg
     4681 tagctgacgg cggtgcaggc ttcgttcagg ttcatgtgga aggaggcgtc accggtaaac
     4741 atcaccacac gctgctggcg tcccagtgcc atctgggcac caatggcggc accgtagcca
     4801 aagcccatgg tgccaaggcc gccgctggtg ataaagccgc ggctcttggt gtggcgcagg
     4861 tactgcgccg cccacatctg gtgctgaccc acgtcggtaa catacacggc gtcggggccg
     4921 cactggttgc acacctcgcc gatgacctga tggggcatca ggcgggtggg gtcggacaca
     4981 gggtggtaat cctgtgcctg ccactcgtgg atcatcttca tccagtcggg gtgcttcttt
     5041 tcctcaatga gggggagcat cccgctcaga acgtagaaga catcaccggc aatggcaaga
     5101 tccacatcca cgttcttgcc cagctcactg g
//
