LOCUS       c00155_gnlPro..        16926 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LANLAPFM_155.
ACCESSION   c00155_gnlPro..
VERSION     c00155_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 07:37:01
            Original ID  :: gnl|Prokka|LANLAPFM_155
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4863
            Orig. end    :: 21789
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16926
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14863:18203]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13340
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..16926
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16926
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             2106..2663
                     /locus_tag="ctg155_7"
                     /transl_table=11
                     /translation="VYGEGFYMVDVAVNRLSNYMDYIPLMISERLIDVNEDMVGQNIYV
                     TGQFRSFNRHEEKKNRLVLSVFVRELEFLDEIDDEVKSNQIFLDGYVCKEPIYRKTPLG
                     REIADLLIAVNRSYGKSDYIPCICWGRNARFASGFDVGGHVQIWGRIQSREYVKKLSET
                     QTEKRVAYEVSVSKIDFLEELD"
     CDS             3082..3948
                     /locus_tag="ctg155_8"
                     /transl_table=11
                     /translation="VAIVTPMKNNEEVNYDRLEQMIEYQINQGTDCIIIAGTTGESSTL
                     TTEEHAEVIKAAVKFAKHRIPVVAGTGSNCTREAIHLSEEAEKAGVDGLLCVTPYYNKA
                     TQGGLIRYYTEIANSVKLPIIMYNVPSRTGCNILPETAAKLYHDVENIVAIKEATGNVA
                     QAAKTMYLTDGKLDLYSGEDGIVVPLMSIGAIGVISVWSNVAPKDVHDMCMAFFDGDTK
                     KAMEIQLKAQPLIEALFSEVNPIPVKKALNLMGMEAGPLRSPLTEMTDANAAKLAEAMK
                     NYGIKLA"
     CDS             4053..4820
                     /locus_tag="ctg155_9"
                     /transl_table=11
                     /translation="MIRAIMSGCNGKMGQVITGICKEDADIEIVAGIDLYDGIKNDYPV
                     FPNISVCDVAADVIIDFSNAKAVDDLLVYSVDKQIPVVLCTTGLSEEQLKKVDGASKKV
                     AVLKSANMSLGINMLMELLKQAATILAPAGFDMEIVEKHHNQKLDAPSGTALALADSMN
                     EALDNAYTYTYDRSKERKKREKTEIGISAVRGGSIVGEHEVIFAGLDEVIEFKHTAYSR
                     SVFAKGAVQAAKFLSGKPAGFYDMGDVIKATIA"
     CDS             4917..6881
                     /locus_tag="ctg155_10"
                     /transl_table=11
                     /translation="MGQTDLRYLKSLSNQYPTIATAATEIINLQAILSLPKATEHFITD
                     VHGEYDQFLHVLKNGSGAIKRKIEDEFGNAISAAEKKAIATLIYYPEQKLEQVLKTEDN
                     LEDWYKVTLYRLIRICKNASSKYTRSKVRKALPKDFAYVIEELLTGRQEISDQEAYYNE
                     IIRSVIRTGRAAELVIAFCNLIRRLVVDHLHVVGDIFDRGPYPNLIMDTLMEHHSVDIQ
                     WGNHDVYWMGAASGSAACICNVIRISAKYGNLDLLEDGYGINLVPLARFAMKWYDKDSC
                     DCFKLDYREDEYDVHDAFLDEKMHKAITIMQFKLEGQLIKENPEFEMEKRLLLDKINIE
                     KGTVCVEETEYPLKDVSFPTIDWEDPYRLSEDEADVMERLVTAFVNCEKLQRHVRFLYT
                     QGSLYKVYNGNLLYHGCVPLNEDGTFTRVNVFGKEYAGKELYDVLEGYARKGYYAIDPK
                     EKKKGQDILWFIWENQNSPVFGKAKMTTFERYFIADKKTHQEPKNPYYRLLEKEEVVNR
                     ILEEFGLEGAEAHIINGHIPVEAKKGESPVKCNGKLLIIDGGFSKAYQPKTGIAGYTLI
                     YNSYGLVLAAHEPFESVEKAVQDGSDIVSHTVLVQQVVRRKTVADTDIGKSLKESIHDL
                     EELLAAYRAGTIVEKNRAE"
     CDS             6965..7792
                     /locus_tag="ctg155_11"
                     /transl_table=11
                     /translation="MLIGNHLSASKGYVAMGKAALALDANTFAFFTRNPRGGKAKEIDE
                     KDVEKFLNFAKEHEFGKIVAHAPYTMNLCAAKEDVRSFSKEMLLDDLKRMEYTPYNYYN
                     FHPGSHVGQGAEKGIALIEEALNEALKPEQTTTVLLETMAGKGTEVGRTFEELREILDR
                     VELNDKMGVCLDTCHVWDGGYDIVNDLDGVLNEFDRVIGLDRLKAVHFNDSMNDCGSHK
                     DRHAKIGEGKIGAEAMRRVALHPLLEGRPFILETPNDDEGYRREIQMVREWTR"
     CDS             complement(7724..7888)
                     /locus_tag="ctg155_12"
                     /transl_table=11
                     /translation="MANAITYSVKFWYFLFYFVLGYFYFLFRFAAILPRPLPDHLYLPS
                     VPLIIVRCL"
     CDS             complement(7969..8319)
                     /locus_tag="ctg155_13"
                     /transl_table=11
                     /translation="MFFPDITVRLKNAKKEQASITCSSIVVIIIVILYVIYLHSAKTIF
                     SRVRVGTIASKYLRILLLLTVSQVILDSGYHPRNQLIKFELLTQSITRLTPQSAVAPPV
                     RMGLTNLLVGKQ"
     CDS             8377..9831
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg155_14"
                     /sec_met_domain="OKR_DC_1_C (E-value: 2.1e-12, bitscore:
                     37.9, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 1.1e-130,
                     bitscore: 426.2, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKEQQMRAPVYEALEKLKKRRVVPFDVPGHKRGRGNPELVELLG
                     EKCVSLDVNSMKPLDNLCHPVSVIKEAEELAAEAFRAEHAFFMVGGTTSSVQGMVLSCC
                     KAGDKIILPRNVHKSVINALVLCGAIPVYVNPEVDVKLGISLGMQVSEVERAILENPDA
                     VAVLVNNPTYYGICSDLRSIVRVAHEHHMLVLVDEAHGTHLYFGENLPVCAMDAGADMA
                     SVSMHKSGGSLTQSSLLLTGKGVNWEYVSQIINLTQTTSASYLLMSSLDISRRNLALRG
                     KESFAKVAQMAEYARDEINSIGGFYAYGKDMVNGGSVYDFDVTKLSVYTRDIGLAGIEV
                     YDLLRDEYDIQIELGDIANILAYISIGDRIQDIERLVGALADIKRLYSKDPAKMLNTEY
                     INPKVLVSPQVAFYSQKESMPVRQTAGRICGEFVMCYPPGIPILAPGEMITPEIIEYIV
                     YAKEKGCSMQGTEDPEVENLNVLAKK"
     CDS             10001..10762
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg155_15"
                     /sec_met_domain="Spermine_synth (E-value: 3.7e-52,
                     bitscore: 166.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VFDSDEFGRFLSSDGSIVFSEKDEFVYDEMIVHVPMAVHPHVKKV
                     LVIGGGDGGVARELGYYDEIEQIDVVEPDRVFVEVCKEFFPDNACGLSDERVTVYYEDG
                     LKFLRMKHDEYDLIINDAIDPLGHTAGLFTKEFYGNCFRALKDDGIMVYQHGSPFYDED
                     EESCRGMHRKASHSFPISRVYQAHIPTCSSGYWLFGFASKKYHPLDDLDAKRWKERKIK
                     TWYYTTNLHKGAFMLPRYVEDMLEEEEGRKK"
     CDS             11037..12119
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg155_16"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 6.9e-45, bitscore:
                     144.5, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 4.4e-20,
                     bitscore: 62.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VDADNTEELIALIKKYQPDAVLNVALPYQDLTIMDACLACKVDYI
                     DTANYEPEDTDDKEWRAIYEKRCKEEGFTAYFDYSWQWAYREKFKEAGITALLGSGFDP
                     GVTSVFTAYALKHYFDEIETIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWENGH
                     WVETKPMEIKREYNFPQVGEKDMYLLHHEEIESLAKNVPGVKRIRFFMTFGQSYLTHMK
                     CLENVGMLSTSPIEYEGREIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGKKDGKEK
                     TIYIYNVCDHQECYKEVGSQAISYTTGVPAMIGAALVVDKVWDKDGVFNIEEFDPDPFM
                     DMLNQYGLPWVVDENPQTVA"
     CDS             12240..13340
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg155_17"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 2.3e-13,
                     bitscore: 40.7, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVDEKKLKQNLKILQNLEQETGCHVLLAQKAFSMFSLYPLIGQYI
                     SGTTASGIFEARLGKEEMGKENHVFAPAYKEKDMEELVQICDHVIFNSFAQYEKYQHYF
                     LQQECTASAGIRVNPECSTQEGHEIYDPCGPGSRLGVVKSEFPDQLPEGIEGLHFHTLC
                     EQNADDLITTWHAFEEKFGSYLKQVKWLNLGGGHHITRADYQLDELKKLICEIRRKYNV
                     RVYLEPGEAIALNAGYLVTEVMDIVHNGMDILILDASAACHMPDVLEMPYRPPLKDGYL
                     PGEKPHTCRLSSMTCLAGDVIGDYSFAQKKQVGDRLVFEDMAIYSMVKNNTFNGMPLPG
                     IAVLREDGDVEMIKEFGYEDFKGRLS"
     CDS             13312..14535
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg155_18"
                     /sec_met_domain="PAD_porph (E-value: 2e-117, bitscore:
                     382.4, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISKADCPEMIKDTTPVQDGFFMPGEFEQHQGCIMIWPERPGSW
                     RNGAEEAETAFSAVIRAIAASETVYVAAGKKGLDHAKAFAESLKKEENLHPVVVFEMET
                     DDSWARDVAPTFLVNRTDGKISDLTAAGNGTAQTGDDVKNSQVRGVNWSFNAWGGEVDG
                     LYASYEKDNAFAWNFCRKFEFDCYDAEPFVLEGGSIHSDGEGTLLVTESCLLSAGRNPS
                     LTKEQIEEQLKCYLGVEKVLWLPRGIYQDETNEHVDNVCAFLRPGEVVLAWTNNQNDPQ
                     YAMSKASFDYLSSVRDAKARKLIIHKLPIPDIPVCITKEELEGYEFEEGEDVREVGERL
                     AASYVNFYFSNNAVVMPVFGGENEESDLRAQQIMAKLCPDRKIIPVYARDILTGGGNIH
                     CITQQIPL"
     CDS             14691..15503
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg155_19"
                     /sec_met_domain="CN_hydrolase (E-value: 9.3e-48, bitscore:
                     153.1, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKAAAEGANIILLPELFEREYFCQQRRYDFYSYARTVEESEAV
                     AMGVRLAKELGVVLPISFYERDVNNLYNSIACIDGDGTILGVYRKTHIPDDHYYQEKFY
                     FTPGDTGFKVFDTKYGCIGIGICWDQWFPETARAMALLGAELLFYPTAIGSEPILECDS
                     MPHWRRCMQGHAAANLMPVIAANRIGREVVQPCAENGGQESALEFYGSSFLTDETGEVI
                     LSASRDKEEILSQTYELDELRAKRLEWGLFRDRRPEYYGIIAGEKNGR"
     CDS             complement(15739..16749)
                     /locus_tag="ctg155_20"
                     /transl_table=11
                     /translation="MEHLIIPKDYHSELNLHDTQIAIKTVKDFFQNLLALRLNLSRVSA
                     PLFVDPLSGLNDNLNGIERPVTFDIKEQNGKEAEVVQSLAKWKRYALKKYGFDYGEGLY
                     TDMNAIRRDEDTDNIHSIFVDQWDWEKIIHKEDRNIETLKETVTTVYNCLRKTEKYMAI
                     QYDYIEEILPHDIFFITTQELEEMFPDNTPKEREYYITKTKGAVCIMKIGDTLENGEPH
                     DGRAPDYDDWSLNADIVVYYPVLDIALEISSMGIRVDKKALLSQLKKAGCEERAKLPFQ
                     KAIINEELPYTIGGGIGQSRICMFFLRKAHIGEVQSSLWPEAIAKECEKNGIQLL"
ORIGIN
        1 atgaagtcaa gtgcctgctc taagcttaaa acttttggcg gaaccagtgt cagtgcttca
       61 tcagcagaag aagaacgtgt attggtaaga tgttttttct tacatacgtt taactcgata
      121 tcctcagctc ttgcacagga accgatgacc attccggcat aaactttttc gccaggtccg
      181 ataaataaag taccgcggtc ctgggcagag aacagaccat aagttacgga ttcgccggat
      241 tcaaatgcga tcagggaacc aagtttacgg tatgcgatct caccacggta aggagcatag
      301 ccgttgaaaa tggtattgat gataccgttt cctttggtgt ctgtcatgaa atctccacgg
      361 taaccgatga gaccacggga tggaatatta aactccagac gggtgtaacc gccggtgatc
      421 ggtttcatat tgacaagctc acctttacgc tggcttaatt tatcgataac agtaccggta
      481 aactcatccg ggacatcgac gtaagcgatc tccataggct ctgtcttttt accgttctcg
      541 tctgtgtggt ataaaacttc tgctttgctg actgcaaact cataaccttc acggcgcatg
      601 ttctcaacta aaacggataa gtgaagctca ccacggccgg atactttgta gcagtccgga
      661 ctctctgtct cttctacacg cagagaaaca tcggtattta attctttgaa cagacggtct
      721 cttaaatggc gggaagtgat gaatttacct tcctgtccgg cgagcgggct gtcgtttacc
      781 atgaagttca tggaaagcgt aggctcagaa atcttctgga acggtattgc aaccggattt
      841 tccggtgcac agatcgtatc tccgatgtgg atatctgcga taccggagat tgctacgatc
      901 gatccgatct ttgcttctgc gacatctact ttatttaagc cgtcaaattc atataatttg
      961 ctgatgcgga cttttttctg tttgtccggt tcatgatggt ttaccacaac agcttcctga
     1021 tttactttta agcatccgtt gtcgacttta ccgataccga tacgtccgac atactcgttg
     1081 taatcgatgg tactgatgag tacctgtgtg tttgcatccg gatcaccttc tggagccgga
     1141 atgtaatcaa tgatggtctc aaacagaggt gtcatatctt ttttgttatt tacaagatcc
     1201 ccgatctcgc gaacggcata accgtctctt gcagatgcaa acaggaacgg acagtctaac
     1261 tgctcatcgg atgcgtctaa gtccatgaat aactcaagta cttcatcgac aacctcgttc
     1321 gggcgggctt ccggacggtc tactttattt aaacatacga taaccggaag agaaagttct
     1381 aatgctttca tcagtacgaa tttggtctga ggcataacac cctcgaatgc gtcaacgaca
     1441 aggataacac cgtttaccat tttaaggaca cgctcaacct caccaccaaa gtccgcatga
     1501 ccaggagtat cgatgacatt gatctttgta cctttatagg taatggctgt gttttttgaa
     1561 aggatcgtga taccacgttc tctctcgata tcattggagt ccatgacacg ttcctgaact
     1621 tcctgattcg cgcggaatac gccgctctgc tttagcagct catcgaccag agttgtttta
     1681 ccgtggtcaa cgtgtgcaat aatggcaata ttacggacat cttcacgttt cattttcata
     1741 tacaaaatct ctctttcctg tgtgaaatgt attaactgta acataaggtt aaaaaaccaa
     1801 cctatatatt ttatcatatt tgtggaattc tgcaatattt ttttattcaa aaacctgaca
     1861 aaagttgtca ttacattcgt tttcttatcg acatgttcca tgaaaatttg aatgtgatac
     1921 atggtaaaaa tattatgtca ggcaggtcat accgggcaga aacggttcga aaagaaaaaa
     1981 cgcacaaaaa aatataggtg tatgaccgca aggaagggag aatattcatg gcagataaaa
     2041 tgtttgaaaa caaccaggtg tcgatcgtgg gggagattgt atcggatttc cggttcagcc
     2101 acgaagtgta cggagaggga ttttatatgg tcgacgtggc agtcaaccgt ctcagcaatt
     2161 atatggatta cataccattg atgatttcgg aacgattgat cgatgtcaat gaggacatgg
     2221 tcggacagaa tatttatgtg acaggacagt tccgctcatt caaccggcac gaggaaaaga
     2281 aaaaccggct tgtactttcc gtttttgtga gagaactgga atttttagac gagattgacg
     2341 atgaggtaaa gagcaaccag atctttttag acggctatgt atgtaaggag ccaatttacc
     2401 ggaaaacacc gcttggaaga gagatcgcag atcttctgat cgctgtgaac cgctcttatg
     2461 gaaaatcaga ttacattccg tgcatctgct ggggacgaaa tgcaagattt gcctccggtt
     2521 ttgatgtggg cggacatgtg cagatctggg gcaggatcca gagccgcgaa tatgtcaaaa
     2581 aattatcgga gacgcagacg gaaaaaaggg ttgcatacga agtatccgtc agcaaaattg
     2641 attttttaga ggaattggat tgacagtaga aatagatggt gctatgattg ctaaaagata
     2701 catattgctt gatagaggtt gcgtgcttta agagtagttt tccggatgtg gcagaagcag
     2761 aggatggagg ataaaaggaa agaacgccga aggagtatat ttgctgcgga tatgttcctg
     2821 ggcataaggt aaagaacctt atgactgtca tcttaagctg aaatggcaga aagatggggc
     2881 gctatcggat tcgacatata ctgggtaata catatgatta gaatttacga accggctcat
     2941 cagagtcggt ttttttaatt catagggaaa ttacgtccta tgaataaata aaataccgtg
     3001 tgcacaaagc agtgtatcct aacgtatcat aatacaggaa ccaggaggat tattaatatg
     3061 tctattttta aaggagccgg tgtggcaatc gtaacaccaa tgaaaaacaa tgaggaagta
     3121 aattatgaca gattagagca gatgatcgag tatcagatca atcagggaac ggactgtatc
     3181 attatcgcag gtacaacagg tgagagctct acgctgacga cagaagagca tgcagaggtg
     3241 atcaaagctg ctgttaaatt tgcaaaacac cgtattccgg tcgttgcagg aaccggttca
     3301 aactgtacaa gagaggcaat ccacctttcg gaagaagcgg aaaaagccgg cgtggatgga
     3361 ctgctctgcg taactccata ttataacaaa gcaacacagg gaggtctgat ccgctactac
     3421 acagagattg caaattctgt aaaacttcct attatcatgt acaatgttcc aagccgtacc
     3481 ggatgcaata tccttccgga gacagctgca aaactgtacc atgatgttga aaacatcgtt
     3541 gcgatcaaag aggcaaccgg aaatgttgca caggcagcaa agaccatgta tttaacggat
     3601 ggaaagcttg atctgtattc cggcgaggat ggaatcgtag taccgttaat gtcgatcgga
     3661 gcaatcggtg tgatctccgt atggtcaaac gtggcaccga aggatgtaca tgatatgtgt
     3721 atggcattct ttgacggaga tacgaaaaaa gcaatggaga tccagctaaa ggcacagccg
     3781 ctcattgagg cgctgttctc cgaagtgaac ccgatccctg ttaagaaagc gctgaatctg
     3841 atgggcatgg aggcaggacc gcttcgttcc ccgctcacag agatgacaga tgccaatgct
     3901 gcaaaacttg cggaagcaat gaagaattat gggatcaagc tggcgtaagg ggcagtggaa
     3961 cacggaaagc cagatttgaa aaaacaccgg aaatgttggt tcgcagcgtt tccggtgttg
     4021 ctttaaataa agaaaagaga ggaaaaaaca atatgataag agcaattatg agtggatgta
     4081 acggaaaaat gggacaggtg atcacaggaa tctgcaagga agatgcagat attgagatcg
     4141 tggcaggaat tgacctctac gatggcatca aaaacgatta cccggtattt ccaaatattt
     4201 ctgtctgtga tgtggcagcg gatgtgatca ttgatttttc caacgcaaaa gcagtggatg
     4261 atcttttggt atacagtgtg gacaagcaga tcccggtcgt actctgcacg accggactct
     4321 ccgaggagca gttaaaaaag gtggacgggg catcgaaaaa agttgccgta ttaaaatctg
     4381 ccaacatgtc gcttggaatc aatatgttaa tggagctgtt aaaacaggct gcaaccattt
     4441 tagcaccggc cggttttgat atggagatcg tcgaaaaaca ccacaaccag aaactggatg
     4501 cgccgagcgg tacggcactt gcacttgccg attccatgaa tgaggcactt gacaatgcat
     4561 atacctatac ttatgaccgc agcaaagagc gcaaaaagag agaaaaaaca gagatcggta
     4621 tctctgcagt gcgtggcggc agcatcgtag gagaacatga ggtgatcttt gcaggacttg
     4681 acgaggtgat cgagtttaag catactgcat attccagaag tgtatttgca aagggcgctg
     4741 tgcaggcggc aaaattcctg tccggaaaac cggcgggatt ctatgatatg ggggatgtga
     4801 tcaaggctac gatcgcgtag agcattgaca ataaattaac gttggttgcc cccgctcatt
     4861 tcctatgata agataaaaaa gcagcaaatg aacgtgaaaa agaaatgagg aatactatgg
     4921 ggcagaccga cctgcgttat ttaaaaagtt tatcaaatca gtatccgacc attgccacag
     4981 cggcgacaga gattatcaat ttacaggcga ttcttagcct gccaaaagca acagaacatt
     5041 ttatcacaga tgtgcacggg gagtacgacc agtttttaca tgtgctaaaa aatggatccg
     5101 gtgccatcaa gcggaaaata gaggatgaat ttggcaatgc aatcagcgcg gcggagaaaa
     5161 aagcgatcgc cacgctgatc tattacccgg aacagaagtt ggaacaggtg ttaaagacgg
     5221 aagataattt ggaggactgg tacaaagtca ccttataccg cctgatccgc atctgtaaaa
     5281 atgcatcttc caagtataca aggtcaaaag tgcggaaagc acttccaaaa gactttgcct
     5341 atgtgattga ggaacttttg accggcagac aggagatatc cgatcaggag gcatattata
     5401 atgaaattat ccggtcggtc atccgcaccg gaagggcggc ggagcttgtg atcgcgttct
     5461 gtaatctgat ccgccggctt gttgtggatc atctgcatgt ggtcggggat atttttgaca
     5521 ggggaccata tccgaatctg atcatggaca cactgatgga gcatcactct gtggacatcc
     5581 agtggggcaa tcacgatgtg tactggatgg gagcggcgtc gggcagtgcg gcatgcatct
     5641 gtaatgtgat ccgcatttct gcaaaatatg gaaaccttga tctgttagag gacggttacg
     5701 ggattaatct ggtgccgctg gcaagatttg cgatgaagtg gtatgataag gattcctgtg
     5761 actgttttaa gctggattac cgggaagatg aatatgatgt gcacgacgca tttttagatg
     5821 aaaaaatgca taaggcgatc acgatcatgc agtttaaact ggaaggtcag ctgatcaaag
     5881 aaaacccgga atttgagatg gagaaaagac ttcttctcga taagatcaac atcgaaaagg
     5941 ggaccgtgtg tgtggaggaa accgagtatc cgctcaagga tgtcagtttt ccgacaatcg
     6001 actgggaaga tccatatcgt ctctcagaag atgaggcgga tgtgatggag cgtcttgtga
     6061 ctgcatttgt gaactgtgaa aaactgcagc gtcatgtgcg ttttttgtat acacagggaa
     6121 gtctttacaa agtatataat ggaaaccttc tctaccatgg ctgcgtgccg ctgaatgagg
     6181 atggcacgtt taccagagtt aacgtttttg gaaaagaata tgccggaaaa gagctttatg
     6241 atgtgcttga gggctacgcg cgaaaaggct attatgcgat cgacccgaag gagaagaaaa
     6301 agggacagga cattttatgg tttatctggg aaaaccagaa ttccccggtg tttggaaagg
     6361 caaagatgac gacgtttgag cgttatttta ttgcagataa aaaaacgcat caggagccga
     6421 aaaatcctta ttacaggctg cttgaaaaag aggaagtggt caaccgtata ctagaggaat
     6481 tcgggcttga aggtgcggag gcgcacatca ttaacggtca tattccggtg gaggcaaaaa
     6541 aaggagagtc tccggtcaaa tgtaacggaa agcttctgat cattgacggc ggtttttcca
     6601 aggcatatca gccaaagaca gggattgccg gatatacgct gatttataat tcttatggtc
     6661 tggtgcttgc ggcgcatgaa ccgtttgaat cggtagaaaa agcggtgcag gacggaagcg
     6721 atatcgtatc ccatacggtt ctggtgcagc aggtcgtgcg gagaaaaacg gttgccgata
     6781 cagatatcgg aaaaagttta aaagagtcga tccatgatct tgaggagctg ctcgcggcat
     6841 acagagcggg cacgatcgtg gagaagaacc gggcagaata aaagagcatt cgcgtataca
     6901 gacaggagta ttattgtgca caaaattaag gtgcgcgaag cgcagtgcag aaatgaggat
     6961 tgatatgtta ataggaaatc atttatccgc atccaaagga tatgtggcga tgggaaaggc
     7021 agcgctggcg ttagatgcca atacctttgc tttttttaca agaaatccgc gtggcggtaa
     7081 ggcaaaagaa atcgatgaaa aagatgtgga aaagttttta aattttgcga aggagcacga
     7141 atttggaaag attgttgcgc atgcgccata tacgatgaac ctctgcgctg caaaagagga
     7201 tgtccgttct ttttcaaagg aaatgctgct tgatgactta aaacgcatgg agtatacacc
     7261 gtacaattat tataattttc atccgggttc ccatgtggga caaggggcgg aaaaagggat
     7321 cgcattgatt gaggaagcat taaatgaagc cttgaaaccg gagcagacaa cgaccgtttt
     7381 acttgagacg atggcgggaa aaggaactga ggttggaaga acgtttgagg agttaagaga
     7441 aatcttagac cgtgtggaat taaacgataa aatgggagtc tgcctcgata cctgccatgt
     7501 gtgggatggc ggttatgaca ttgtaaacga ccttgacggt gtgttaaatg agtttgaccg
     7561 tgtgatcggg ctcgaccggc tgaaggcagt tcactttaat gacagcatga acgactgtgg
     7621 ctcccacaag gaccgtcatg cgaagatcgg tgagggaaag atcggtgcag aggcgatgcg
     7681 gcgcgttgca ttgcacccgc ttttagaagg aagaccgttt atcttagaga caccgaacga
     7741 tgatgagggg tacagacggg agatacagat ggtccgggag tggacgcggt aagatcgctg
     7801 caaacctgaa tagaaaataa aaatatccta aaacgaaata aaaaagaaaa taccagaatt
     7861 ttacagaata cgttattgca tttgccatgt gtgtatgcta tacttcaaat cacatgaatg
     7921 cgaaaattgt tttcatgcaa atattcgtta caatagatgg aaaaggatct attgtttgcc
     7981 caccaagaga ttggttaagc ccatacggac aggcggggca actgccgatt gcggtgtaag
     8041 ccgcgttatt gattgagtta gaagctcaaa ttttataagt tgattacggg gatgataccc
     8101 ggaatccaat atcacttgtg aaacggtcaa taagagtagt atacgcaaat atttgctggc
     8161 gatggtgcca acgcggactc tggagaaaat agtttttgca gaatgtagat agattacata
     8221 aagtatgact atgatgataa cgacgataga agaacaggtg atggatgcct gttctttttt
     8281 tgcgtttttc agcctgacgg taatgtcagg gaaaaacatt tgatgaaaag cagagcatgc
     8341 agatttttat ggaagccaag ggggattttt ttagtcatgg acaaagagca gcagatgcgt
     8401 gcgccggttt atgaggcact ggaaaagtta aaaaaacgaa gagtggtgcc gtttgatgtg
     8461 ccgggacata agagaggaag gggaaatccg gagctggtag agctgttggg agaaaaatgt
     8521 gtgagtctgg atgtcaattc catgaagccg cttgacaatc tctgtcatcc ggtttcggtg
     8581 atcaaggaag cggaggagct tgccgcggag gcatttcgcg cggaacatgc attttttatg
     8641 gttggcggaa ccacttcctc cgttcaggga atggtgcttt cctgctgtaa ggcaggggat
     8701 aagatcattt tgccgcgaaa tgtgcacaag agtgtgatta atgcactggt gctctgtgga
     8761 gcgattccgg tttacgtcaa tccggaggtt gatgtgaaac ttggcatttc actgggaatg
     8821 caggtgtcag aggtggaacg tgcgatttta gagaacccgg atgcagtagc agttttagtc
     8881 aacaatccga cttactatgg aatctgttcg gatctgcggt ctatcgtgag agtggcgcat
     8941 gaacatcata tgctggtgct ggtggatgag gcacacggaa cgcatctgta ttttggggaa
     9001 aatcttccgg tatgtgccat ggatgccggg gcggatatgg cgtctgtctc catgcacaag
     9061 tcggggggaa gcctgacgca gagctctctt cttctgaccg gaaagggtgt gaactgggaa
     9121 tatgtcagcc agatcatcaa tctgacgcag acgacgagtg catcttatct tctgatgtcg
     9181 agccttgata tttcgcggag aaaccttgcc ttgcgaggga aggaatcttt tgcgaaagtg
     9241 gcacagatgg cggagtacgc gagggatgag atcaattcta tcggtggatt ttatgcgtat
     9301 ggcaaagata tggtaaacgg tggcagtgtc tatgattttg atgtgacaaa actgtctgta
     9361 tatacgagag atatcgggct tgcaggcatt gaggtctatg atctgctgcg ggatgaatat
     9421 gatattcaga tcgagcttgg agatatcgca aatattcttg cctatatttc catcggtgac
     9481 cggatacagg atattgagcg gcttgtgggt gcacttgcag acatcaaacg gctgtattcg
     9541 aaagatccgg caaaaatgct gaatacggaa tatattaatc cgaaggtttt agtgtcgccg
     9601 caggtggcat tttattcgca aaaggaatcc atgccggttc gtcagacagc gggaaggatc
     9661 tgcggtgaat ttgtcatgtg ctatccgcct ggaattccga ttttagcgcc gggtgagatg
     9721 atcacgccgg agatcattga gtacattgtt tatgcaaaag aaaagggatg ctctatgcag
     9781 ggaacggagg atccggaagt tgaaaatctg aatgtgcttg caaagaaata acagcataga
     9841 tcagcaaaaa taaagattcc tgtgaaaaga agattttttc aaaagaaggg ggaagatcat
     9901 ggaactttgg ttttcggatt atcacacgga aaaagtcaag gtgtcggtca aggtgcagaa
     9961 acagttattt ggtttacaga ccgagtttca gcggatcgat gtgtttgatt cggatgagtt
    10021 tgggcgtttt ttaagttccg acggtagtat tgttttttcg gaaaaagatg agtttgtcta
    10081 tgatgagatg attgtgcatg ttccgatggc ggtgcatccg catgtgaaaa aggtgttagt
    10141 catcggcggc ggtgacggcg gcgtggcacg agagcttggc tattacgatg agatagagca
    10201 gatcgatgtc gtggagccgg atcgtgtatt tgtcgaggtc tgcaaggaat tttttccgga
    10261 caatgcatgc gggttatcgg atgaacgcgt gacggtgtac tatgaggatg gattgaaatt
    10321 tttgcggatg aaacatgacg agtatgatct gatcatcaac gatgcgattg atccgcttgg
    10381 acatactgca ggactgttta ccaaggaatt ttacggaaac tgcttccgtg ccttaaaaga
    10441 tgacggaatc atggtatatc agcatggaag tccgttttac gatgaagatg aggaatcctg
    10501 ccgcggtatg caccggaaag cgagtcatag ctttccaatc agccgcgtgt atcaggcaca
    10561 tataccaacg tgttcttccg gatactggct gttcgggttt gcgtcaaaga aatatcatcc
    10621 gctcgatgat ctggatgcaa agcgctggaa agagcggaag ataaaaacct ggtattatac
    10681 caccaatctg cacaagggag catttatgct gccgcgatat gtggaggata tgttagagga
    10741 agaagaagga cgtaagaaat aataaaaatt aaattaaaat ttattttttc acacgcaaga
    10801 tttgtgcccc ggcacaaact tgagatgcgc aaaaagacag cgcaggaaag gagattaaaa
    10861 tgggaagatt attaattatc ggatgtggcg gagttgcagg agttgcgatt cacaaatgct
    10921 gccagaacag caaaactttt acggagatct gcattgcgag cagaacaaaa tcgaaatgtg
    10981 atgccttaaa agaaaaactg gaaaaaacaa cggacactgt catcacaaca gcacaggtgg
    11041 atgcggacaa tacggaggaa ctgatcgccc tgatcaaaaa atatcagccg gatgctgtgt
    11101 taaatgttgc tttgccatat caggatttaa caattatgga tgcctgcctt gcatgcaaag
    11161 tagactatat cgatactgca aattatgagc cggaggatac ggatgacaaa gaatggcgtg
    11221 ccatctatga aaaacgctgt aaagaagagg gatttacagc atattttgac tattcctggc
    11281 agtgggcata ccgtgaaaaa ttcaaagagg caggaattac ggcattgctt ggaagcgggt
    11341 ttgatccggg agtgaccagt gtatttaccg cttatgccct gaaacattat ttcgatgaga
    11401 tcgagacgat tgatatctta gactgtaacg gcggcgacca cggctatccg tttgcaacca
    11461 attttaaccc ggagatcaac ctgcgtgagg tttccgcaaa cggttcttac tgggagaatg
    11521 gtcactgggt agaaacaaaa ccaatggaaa ttaaaagaga atataatttt ccacaggttg
    11581 gcgagaaaga tatgtatctg ctgcatcatg aggaaattga gtcccttgca aaaaatgtac
    11641 ctggagtaaa gcggatccgt ttctttatga cctttggaca gagctatctg acacatatga
    11701 aatgtttaga aaatgtcgga atgctctcaa catcaccgat cgagtatgag ggcagggaga
    11761 tcgtaccaat ccagttctta aaagcactgc ttccggatcc tgcatcatta ggaccgcgca
    11821 cggttggaaa aacaaatatc ggctgtatct ttacgggaaa aaaagacgga aaagaaaaga
    11881 cgatttatat ctataatgtc tgtgaccatc aggaatgtta caaagaagtc ggttcccagg
    11941 caatttctta tacaacaggt gttccggcta tgatcggtgc agcgttagtt gtcgataaag
    12001 tctgggacaa agacggtgta ttcaatattg aagagtttga tccggatccg tttatggata
    12061 tgttaaacca gtatggtctg ccatgggttg tggacgaaaa tccgcagacg gtggcataaa
    12121 ataagaatat gtgtgaaacg ggttggataa aattttaaat ttgtcagctt ttgcgcagcg
    12181 gatttttgca gaaatggaga attatcatga aatggcagga gattcctacc ccgtgttatg
    12241 tggtagatga aaagaagcta aaacaaaatt taaaaatatt gcagaatttg gaacaggaaa
    12301 ccggctgcca tgtgcttctg gcacagaagg cattttccat gttttcactg tatccgctga
    12361 tcgggcagta tatcagcgga acgacggcga gcggaatctt tgaggcgcgc cttggaaaag
    12421 aggagatggg aaaggaaaat catgtatttg caccggctta taaggaaaaa gatatggaag
    12481 aactggtgca gatctgcgat cacgttattt ttaattcctt tgcgcagtat gaaaagtatc
    12541 agcactattt tttgcagcag gagtgcactg caagtgccgg gatccgcgtg aacccggagt
    12601 gctccacaca ggaagggcat gagatctatg atccatgcgg accgggatca aggcttggtg
    12661 tggttaaaag tgaatttccg gatcaactgc cggagggaat cgaaggatta cattttcata
    12721 cactctgcga gcagaatgcg gatgatctga tcacgacctg gcatgcgttt gaggagaagt
    12781 ttggcagtta tttaaaacag gtaaaatggc tgaacttagg cggcggtcat catattacaa
    12841 gagcagacta tcagttggat gaactaaaga agttaatctg tgagatcagg cgaaaatata
    12901 atgtccgggt atacctggaa ccgggtgagg cgatcgcatt aaatgcgggc tatcttgtca
    12961 cggaggttat ggatatcgta cacaatggaa tggatatcct gattctggat gcatcggcgg
    13021 catgccacat gccggatgtg cttgaaatgc catatagacc gccgctaaaa gacggttatc
    13081 tgccgggcga aaagccgcat acctgccggc tttcttccat gacctgcctt gccggcgatg
    13141 tgatcggtga ttacagcttt gcacagaaaa aacaggtggg agaccgtctg gtctttgagg
    13201 atatggcaat ttattccatg gtcaaaaaca atacatttaa cgggatgccg ctgcccggaa
    13261 ttgcagtctt acgggaagat ggagatgtcg agatgataaa ggagtttggt tatgaagatt
    13321 tcaaaggcag actgtcctga gatgataaaa gatacaacac cggtacagga cggatttttc
    13381 atgccgggtg agtttgagca gcatcaggga tgtatcatga tctggccgga gcgacccggt
    13441 tcctggagaa atggcgcgga ggaagcagaa acagcgtttt cagctgtgat ccgtgcaatc
    13501 gccgcgagtg agacagtgta tgtcgctgcc ggaaaaaagg ggcttgacca tgcaaaagca
    13561 tttgcggaaa gtctgaaaaa agaagaaaac ttacatccgg tggttgtctt tgagatggag
    13621 accgatgatt cctgggcgcg ggatgttgcg ccgacctttc tggtaaacag aacggatgga
    13681 aagatttcag acctgacagc agcaggaaat ggtacggcgc agacaggtga tgatgtaaaa
    13741 aactcacagg tgcgcggtgt aaactggtct tttaatgcct ggggcggtga agtggatgga
    13801 ctatatgctt cttatgaaaa agacaatgcg tttgcatgga atttctgcag aaaattcgag
    13861 tttgactgtt atgatgccga accgtttgtg ttagagggcg gttctatcca cagcgacgga
    13921 gagggaacat tgcttgtcac ggagtcctgt ctgctcagtg cggggagaaa cccatcgctt
    13981 acaaaggagc agattgaaga acagttaaag tgttaccttg gcgtggagaa agttttatgg
    14041 ctgccacgcg ggatctatca ggatgagacc aacgagcatg tggacaatgt ctgtgcattt
    14101 ctaagaccgg gtgaagttgt gcttgcatgg accaataacc agaatgatcc gcagtatgcg
    14161 atgtcgaaag cgagttttga ttatctaagt tcggtgcggg acgcaaaggc cagaaagctg
    14221 atcatccaca aacttccaat tccggatatt ccggtctgta tcaccaaaga agaactcgaa
    14281 ggatacgaat ttgaggaagg tgaagatgtc agggaagtcg gagaacggct cgccgcctcc
    14341 tatgtaaact tttatttttc caacaatgcg gtagtcatgc ctgtatttgg cggagaaaac
    14401 gaagaaagcg acctgcgtgc acagcagatt atggcaaaac tctgcccgga cagaaaaatc
    14461 ataccggtgt acgcaagaga catattgaca ggcggtggaa acatccactg tattacacag
    14521 caaattccct tatagggaat ttattgtaca accttccata taggagaatt aattcactgt
    14581 gcaaaaataa aaagaacaga aaggatacac gcatgagaca gataaaagca gccgcaattc
    14641 agatgaaatg cgacctggag cacaagaaaa acttacaaaa ggcagaacaa atgatccgca
    14701 aagctgccgc ggaaggcgca aatatcattt tactgccgga actttttgag cgggaatatt
    14761 tctgccagca gcgcagatat gatttttaca gctatgcaag aactgtggag gagagtgaag
    14821 ctgtggcaat gggagtacgt cttgcaaaag aattgggcgt ggtgcttcca atcagctttt
    14881 atgagcgtga tgtcaataac ctctataatt cgatcgcatg cattgatgga gatggaacga
    14941 tcctcggtgt gtatcggaaa acccacatcc cggatgatca ttattatcag gaaaaatttt
    15001 attttacacc gggagatacc ggatttaaag tgtttgatac aaaatacggt tgcatcggta
    15061 ttggaatctg ctgggatcag tggttcccgg agacagcgcg cgcgatggcg ctgctcggtg
    15121 cagaattatt gttttacccg acagcgatcg gctcggaacc gattttagaa tgtgacagta
    15181 tgccgcactg gagacgctgc atgcagggac atgcggctgc gaatctgatg cctgtcattg
    15241 ccgcaaaccg gatcggcagg gaagtagtgc agccatgtgc ggaaaatggc ggacaggagt
    15301 cggcactgga attttatggt tcctcatttc tgacggatga aacaggagag gtgatcttaa
    15361 gtgcttccag agataaagaa gaaatcctga gccagaccta tgaactggat gaacttcggg
    15421 caaaacgact ggaatgggga cttttccggg acagaagacc ggagtattac ggaatcatag
    15481 caggagaaaa aaacgggaga tagtgagaac cagacgggat tgaaaagacc ggaagatagt
    15541 ggaaatcaca cgggactgaa aagaccggaa gatagtggaa accgcacagg actgaaaaaa
    15601 cagaaagatg aaaaaaacag gtatgttttt gtcagcaggg agcagggaaa gctcattgct
    15661 gacatttgaa acatacctgt tttttatcag gcatcagtgt tgatgacagg atatctgcgg
    15721 agcatatgcc cgttcctgtt acaaaagctg aataccgttc ttttcacatt cttttgcgat
    15781 agcttccggc cacagggaag actgtacttc tccaatatgt gccttgcgaa ggaagaacat
    15841 acagatacgg gactgtccga ttccaccacc gattgtataa ggaagctctt cgttgatgat
    15901 cgctttctgg aaaggaagtt ttgcacgctc ctcacagcct gcttttttga gctgggagag
    15961 aagcgctttc ttgtcaaccc ggatacccat ggaagaaatc tcaagtgcga tgtcaagtac
    16021 cggatagtaa acaacgatat ctgcgtttaa ggaccagtca tcgtaatccg gagcacgtcc
    16081 gtcgtgaggc tctccgtttt ccaaagtatc gccgatcttc atgatacata cggcaccttt
    16141 ggtttttgta atataatatt cacgttcctt tggtgtgttg tcagggaaca tttcttccaa
    16201 ttcctgagtc gtgataaaga agatatcatg tggaagaatc tcttctatat aatcgtactg
    16261 gatcgccata tatttttctg tcttgcgcag gcagttataa acagtggtaa ctgtttcttt
    16321 taatgtctcg atattacgat cctctttatg gatgattttt tcccagtccc actggtctac
    16381 gaaaatagag tggatgttat ccgtgtcttc atctctgcgg atcgcattca tatcggtata
    16441 caggccttca ccgtagtcga aaccgtattt ctttaatgcg tagcgtttcc attttgcgag
    16501 agactgtaca acctctgcct ctttcccgtt ctgctctttg atatcgaaag taaccggacg
    16561 ttcaataccg tttaagttgt cattgagacc ggataacgga tcaacaaaaa gtggagccga
    16621 aacgcgggac agattcagac gaagtgcaag caggttctgg aaaaaatctt ttactgtttt
    16681 gattgcaatc tgtgtatcgt gcagatttaa ttctgaatga taatcttttg gaatgattaa
    16741 atgttccatc taaggttctc ctctctggta taaaccgcat gcagcggcat gataccaatc
    16801 ccgtgtgcct gatatatgta tgaaaaagaa aatggcacac taatttatta tagcacagca
    16861 ggtctcattt tcaagaaaag atcatacgat ttcttgaaaa atacatgtat acaatataaa
    16921 ttttag
//
